PMC:6562565 / 37739-38654 JSONTXT

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    MyTest

    {"project":"MyTest","denotations":[{"id":"31244820-23964122-35365963","span":{"begin":30,"end":33},"obj":"23964122"},{"id":"31244820-26317647-35365964","span":{"begin":35,"end":38},"obj":"26317647"},{"id":"31244820-27221704-35365965","span":{"begin":40,"end":43},"obj":"27221704"},{"id":"31244820-24403862-35365966","span":{"begin":45,"end":48},"obj":"24403862"},{"id":"31244820-22116822-35365967","span":{"begin":59,"end":62},"obj":"22116822"},{"id":"31244820-23964122-35365968","span":{"begin":82,"end":85},"obj":"23964122"},{"id":"31244820-27221704-35365969","span":{"begin":87,"end":90},"obj":"27221704"},{"id":"31244820-20080644-35365970","span":{"begin":92,"end":95},"obj":"20080644"},{"id":"31244820-22116822-35365971","span":{"begin":97,"end":100},"obj":"22116822"},{"id":"31244820-27221704-35365972","span":{"begin":109,"end":112},"obj":"27221704"},{"id":"31244820-23964122-35365973","span":{"begin":135,"end":138},"obj":"23964122"},{"id":"31244820-26317647-35365974","span":{"begin":140,"end":143},"obj":"26317647"},{"id":"31244820-27221704-35365975","span":{"begin":145,"end":148},"obj":"27221704"},{"id":"31244820-24403862-35365976","span":{"begin":150,"end":153},"obj":"24403862"},{"id":"31244820-27221704-35365977","span":{"begin":161,"end":164},"obj":"27221704"},{"id":"31244820-22116822-35365978","span":{"begin":183,"end":186},"obj":"22116822"},{"id":"31244820-26317647-35365979","span":{"begin":223,"end":226},"obj":"26317647"},{"id":"31244820-24403862-35365980","span":{"begin":228,"end":231},"obj":"24403862"},{"id":"31244820-22116822-35365981","span":{"begin":233,"end":236},"obj":"22116822"},{"id":"31244820-22116822-35365982","span":{"begin":254,"end":257},"obj":"22116822"},{"id":"31244820-24403862-35365983","span":{"begin":268,"end":271},"obj":"24403862"},{"id":"31244820-22116822-35365984","span":{"begin":284,"end":287},"obj":"22116822"},{"id":"31244820-22116822-35365985","span":{"begin":301,"end":304},"obj":"22116822"},{"id":"31244820-22116822-35365986","span":{"begin":332,"end":335},"obj":"22116822"},{"id":"31244820-24403862-35365987","span":{"begin":414,"end":417},"obj":"24403862"},{"id":"31244820-23964122-35365988","span":{"begin":445,"end":448},"obj":"23964122"},{"id":"31244820-27221704-35365989","span":{"begin":450,"end":453},"obj":"27221704"},{"id":"31244820-20080644-35365990","span":{"begin":455,"end":458},"obj":"20080644"},{"id":"31244820-23964122-35365992","span":{"begin":545,"end":548},"obj":"23964122"},{"id":"31244820-27221704-35365993","span":{"begin":623,"end":626},"obj":"27221704"},{"id":"31244820-27221704-35365994","span":{"begin":641,"end":644},"obj":"27221704"},{"id":"31244820-27221704-35365995","span":{"begin":658,"end":661},"obj":"27221704"},{"id":"31244820-27221704-35365996","span":{"begin":713,"end":716},"obj":"27221704"},{"id":"31244820-26317647-35365997","span":{"begin":735,"end":738},"obj":"26317647"},{"id":"31244820-24403862-35365998","span":{"begin":740,"end":743},"obj":"24403862"},{"id":"31244820-22116822-35365999","span":{"begin":762,"end":765},"obj":"22116822"},{"id":"31244820-26317647-35366000","span":{"begin":779,"end":782},"obj":"26317647"},{"id":"31244820-24403862-35366001","span":{"begin":784,"end":787},"obj":"24403862"},{"id":"31244820-26317647-35366002","span":{"begin":797,"end":800},"obj":"26317647"},{"id":"31244820-24403862-35366003","span":{"begin":802,"end":805},"obj":"24403862"},{"id":"31244820-22116822-35366004","span":{"begin":827,"end":830},"obj":"22116822"},{"id":"31244820-24403862-35366005","span":{"begin":852,"end":855},"obj":"24403862"},{"id":"31244820-24403862-35366006","span":{"begin":872,"end":875},"obj":"24403862"},{"id":"31244820-26317647-35366007","span":{"begin":884,"end":887},"obj":"26317647"},{"id":"31244820-26317647-35366008","span":{"begin":911,"end":914},"obj":"26317647"},{"id":"31244820-27221704-35366077","span":{"begin":641,"end":644},"obj":"27221704"},{"id":"31244820-27221704-35366077","span":{"begin":641,"end":644},"obj":"27221704"},{"id":"31244820-27221704-35366077","span":{"begin":641,"end":644},"obj":"27221704"}],"namespaces":[{"prefix":"_base","uri":"https://www.uniprot.org/uniprot/testbase"},{"prefix":"UniProtKB","uri":"https://www.uniprot.org/uniprot/"},{"prefix":"uniprot","uri":"https://www.uniprot.org/uniprotkb/"}],"text":"A2BR ➣ Antagonists:\nPSB1115 (292, 315, 359, 398)\nATL-801 (399) ➣ Breast:\n4T1.2 (292, 359, 368, 399)\nE0771 (359)\n➣ Melanoma:\nB16-F10 (292, 315, 359, 398)\nLWT1 (359)\n➣ Bladder: MB49 (399) ➣ Primary tumor expansion rate ↓ (315, 398, 399)\nMature T cells (399)\nT cells (398)\nHost A2BR (399)\nHost CXCR3 (399)\nRetained in A2AR−/− mice (399)\nRetained in mice depleted of MDSCs but lost upon adoptive transfer of MDSCs (398)\n➣ Metastasis formation ↓ (292, 359, 368)\nTumor CD73 (292)\nRetained in RAG−/−cγ−/− mice lacking T cells, B cells and NK cells (292)\nRetained in mice depleted of T cells, NK cells D11c+ DCs or macrophages (359)\n➣ Survival↑ (359)\nTumor A2BR (359)\nRetained in mice depleted of T cells or NK cells (359) ↑ CD8+ T cells (315, 398)↑ CXCR3+ T cells (399)↑ NKT cells (315, 398)↓ MDSCs (315, 398)↑IFN-γ, CXCL10 mRNA (399)↑ IFN-γ, TNF-α, GzB (398)↓ MCP-1, IL-10 (398)↓ VEGF (315)↓ Microvessel density (315)"}

    TEST0

    {"project":"TEST0","denotations":[{"id":"31244820-9-16-3850111","span":{"begin":30,"end":33},"obj":"[\"23964122\"]"},{"id":"31244820-14-21-3850112","span":{"begin":35,"end":38},"obj":"[\"26317647\"]"},{"id":"31244820-19-26-3850113","span":{"begin":40,"end":43},"obj":"[\"27221704\"]"},{"id":"31244820-24-31-3850114","span":{"begin":45,"end":48},"obj":"[\"24403862\"]"},{"id":"31244820-9-16-3850115","span":{"begin":59,"end":62},"obj":"[\"22116822\"]"},{"id":"31244820-7-14-3850116","span":{"begin":82,"end":85},"obj":"[\"23964122\"]"},{"id":"31244820-12-19-3850117","span":{"begin":87,"end":90},"obj":"[\"27221704\"]"},{"id":"31244820-17-24-3850118","span":{"begin":92,"end":95},"obj":"[\"20080644\"]"},{"id":"31244820-22-29-3850119","span":{"begin":97,"end":100},"obj":"[\"22116822\"]"},{"id":"31244820-7-14-3850120","span":{"begin":109,"end":112},"obj":"[\"27221704\"]"},{"id":"31244820-9-16-3850121","span":{"begin":135,"end":138},"obj":"[\"23964122\"]"},{"id":"31244820-14-21-3850122","span":{"begin":140,"end":143},"obj":"[\"26317647\"]"},{"id":"31244820-19-26-3850123","span":{"begin":145,"end":148},"obj":"[\"27221704\"]"},{"id":"31244820-24-31-3850124","span":{"begin":150,"end":153},"obj":"[\"24403862\"]"},{"id":"31244820-6-13-3850125","span":{"begin":161,"end":164},"obj":"[\"27221704\"]"},{"id":"31244820-17-24-3850126","span":{"begin":183,"end":186},"obj":"[\"22116822\"]"},{"id":"31244820-34-41-3850127","span":{"begin":223,"end":226},"obj":"[\"26317647\"]"},{"id":"31244820-39-46-3850128","span":{"begin":228,"end":231},"obj":"[\"24403862\"]"},{"id":"31244820-44-51-3850129","span":{"begin":233,"end":236},"obj":"[\"22116822\"]"},{"id":"31244820-16-23-3850130","span":{"begin":254,"end":257},"obj":"[\"22116822\"]"},{"id":"31244820-9-16-3850131","span":{"begin":268,"end":271},"obj":"[\"24403862\"]"},{"id":"31244820-11-18-3850132","span":{"begin":284,"end":287},"obj":"[\"22116822\"]"},{"id":"31244820-12-19-3850133","span":{"begin":301,"end":304},"obj":"[\"22116822\"]"},{"id":"31244820-26-33-3850134","span":{"begin":332,"end":335},"obj":"[\"22116822\"]"},{"id":"31244820-77-84-3850135","span":{"begin":414,"end":417},"obj":"[\"24403862\"]"},{"id":"31244820-26-33-3850136","span":{"begin":445,"end":448},"obj":"[\"23964122\"]"},{"id":"31244820-31-38-3850137","span":{"begin":450,"end":453},"obj":"[\"27221704\"]"},{"id":"31244820-36-43-3850138","span":{"begin":455,"end":458},"obj":"[\"20080644\"]"},{"id":"31244820-68-75-3850140","span":{"begin":545,"end":548},"obj":"[\"23964122\"]"},{"id":"31244820-73-80-3850141","span":{"begin":623,"end":626},"obj":"[\"27221704\"]"},{"id":"31244820-13-20-3850142","span":{"begin":641,"end":644},"obj":"[\"27221704\"]"},{"id":"31244820-12-19-3850143","span":{"begin":658,"end":661},"obj":"[\"27221704\"]"},{"id":"31244820-50-57-3850144","span":{"begin":713,"end":716},"obj":"[\"27221704\"]"},{"id":"31244820-16-23-3850145","span":{"begin":735,"end":738},"obj":"[\"26317647\"]"},{"id":"31244820-21-28-3850146","span":{"begin":740,"end":743},"obj":"[\"24403862\"]"},{"id":"31244820-43-50-3850147","span":{"begin":762,"end":765},"obj":"[\"22116822\"]"},{"id":"31244820-60-67-3850148","span":{"begin":779,"end":782},"obj":"[\"26317647\"]"},{"id":"31244820-65-72-3850149","span":{"begin":784,"end":787},"obj":"[\"24403862\"]"},{"id":"31244820-78-85-3850150","span":{"begin":797,"end":800},"obj":"[\"26317647\"]"},{"id":"31244820-83-90-3850151","span":{"begin":802,"end":805},"obj":"[\"24403862\"]"},{"id":"31244820-108-115-3850152","span":{"begin":827,"end":830},"obj":"[\"22116822\"]"},{"id":"31244820-133-140-3850153","span":{"begin":852,"end":855},"obj":"[\"24403862\"]"},{"id":"31244820-153-160-3850154","span":{"begin":872,"end":875},"obj":"[\"24403862\"]"},{"id":"31244820-165-172-3850155","span":{"begin":884,"end":887},"obj":"[\"26317647\"]"},{"id":"31244820-192-199-3850156","span":{"begin":911,"end":914},"obj":"[\"26317647\"]"}],"text":"A2BR ➣ Antagonists:\nPSB1115 (292, 315, 359, 398)\nATL-801 (399) ➣ Breast:\n4T1.2 (292, 359, 368, 399)\nE0771 (359)\n➣ Melanoma:\nB16-F10 (292, 315, 359, 398)\nLWT1 (359)\n➣ Bladder: MB49 (399) ➣ Primary tumor expansion rate ↓ (315, 398, 399)\nMature T cells (399)\nT cells (398)\nHost A2BR (399)\nHost CXCR3 (399)\nRetained in A2AR−/− mice (399)\nRetained in mice depleted of MDSCs but lost upon adoptive transfer of MDSCs (398)\n➣ Metastasis formation ↓ (292, 359, 368)\nTumor CD73 (292)\nRetained in RAG−/−cγ−/− mice lacking T cells, B cells and NK cells (292)\nRetained in mice depleted of T cells, NK cells D11c+ DCs or macrophages (359)\n➣ Survival↑ (359)\nTumor A2BR (359)\nRetained in mice depleted of T cells or NK cells (359) ↑ CD8+ T cells (315, 398)↑ CXCR3+ T cells (399)↑ NKT cells (315, 398)↓ MDSCs (315, 398)↑IFN-γ, CXCL10 mRNA (399)↑ IFN-γ, TNF-α, GzB (398)↓ MCP-1, IL-10 (398)↓ VEGF (315)↓ Microvessel density (315)"}

    2_test

    {"project":"2_test","denotations":[{"id":"31244820-23964122-35365963","span":{"begin":30,"end":33},"obj":"23964122"},{"id":"31244820-26317647-35365964","span":{"begin":35,"end":38},"obj":"26317647"},{"id":"31244820-27221704-35365965","span":{"begin":40,"end":43},"obj":"27221704"},{"id":"31244820-24403862-35365966","span":{"begin":45,"end":48},"obj":"24403862"},{"id":"31244820-22116822-35365967","span":{"begin":59,"end":62},"obj":"22116822"},{"id":"31244820-23964122-35365968","span":{"begin":82,"end":85},"obj":"23964122"},{"id":"31244820-27221704-35365969","span":{"begin":87,"end":90},"obj":"27221704"},{"id":"31244820-20080644-35365970","span":{"begin":92,"end":95},"obj":"20080644"},{"id":"31244820-22116822-35365971","span":{"begin":97,"end":100},"obj":"22116822"},{"id":"31244820-27221704-35365972","span":{"begin":109,"end":112},"obj":"27221704"},{"id":"31244820-23964122-35365973","span":{"begin":135,"end":138},"obj":"23964122"},{"id":"31244820-26317647-35365974","span":{"begin":140,"end":143},"obj":"26317647"},{"id":"31244820-27221704-35365975","span":{"begin":145,"end":148},"obj":"27221704"},{"id":"31244820-24403862-35365976","span":{"begin":150,"end":153},"obj":"24403862"},{"id":"31244820-27221704-35365977","span":{"begin":161,"end":164},"obj":"27221704"},{"id":"31244820-22116822-35365978","span":{"begin":183,"end":186},"obj":"22116822"},{"id":"31244820-26317647-35365979","span":{"begin":223,"end":226},"obj":"26317647"},{"id":"31244820-24403862-35365980","span":{"begin":228,"end":231},"obj":"24403862"},{"id":"31244820-22116822-35365981","span":{"begin":233,"end":236},"obj":"22116822"},{"id":"31244820-22116822-35365982","span":{"begin":254,"end":257},"obj":"22116822"},{"id":"31244820-24403862-35365983","span":{"begin":268,"end":271},"obj":"24403862"},{"id":"31244820-22116822-35365984","span":{"begin":284,"end":287},"obj":"22116822"},{"id":"31244820-22116822-35365985","span":{"begin":301,"end":304},"obj":"22116822"},{"id":"31244820-22116822-35365986","span":{"begin":332,"end":335},"obj":"22116822"},{"id":"31244820-24403862-35365987","span":{"begin":414,"end":417},"obj":"24403862"},{"id":"31244820-23964122-35365988","span":{"begin":445,"end":448},"obj":"23964122"},{"id":"31244820-27221704-35365989","span":{"begin":450,"end":453},"obj":"27221704"},{"id":"31244820-20080644-35365990","span":{"begin":455,"end":458},"obj":"20080644"},{"id":"31244820-23964122-35365992","span":{"begin":545,"end":548},"obj":"23964122"},{"id":"31244820-27221704-35365993","span":{"begin":623,"end":626},"obj":"27221704"},{"id":"31244820-27221704-35365994","span":{"begin":641,"end":644},"obj":"27221704"},{"id":"31244820-27221704-35365995","span":{"begin":658,"end":661},"obj":"27221704"},{"id":"31244820-27221704-35365996","span":{"begin":713,"end":716},"obj":"27221704"},{"id":"31244820-26317647-35365997","span":{"begin":735,"end":738},"obj":"26317647"},{"id":"31244820-24403862-35365998","span":{"begin":740,"end":743},"obj":"24403862"},{"id":"31244820-22116822-35365999","span":{"begin":762,"end":765},"obj":"22116822"},{"id":"31244820-26317647-35366000","span":{"begin":779,"end":782},"obj":"26317647"},{"id":"31244820-24403862-35366001","span":{"begin":784,"end":787},"obj":"24403862"},{"id":"31244820-26317647-35366002","span":{"begin":797,"end":800},"obj":"26317647"},{"id":"31244820-24403862-35366003","span":{"begin":802,"end":805},"obj":"24403862"},{"id":"31244820-22116822-35366004","span":{"begin":827,"end":830},"obj":"22116822"},{"id":"31244820-24403862-35366005","span":{"begin":852,"end":855},"obj":"24403862"},{"id":"31244820-24403862-35366006","span":{"begin":872,"end":875},"obj":"24403862"},{"id":"31244820-26317647-35366007","span":{"begin":884,"end":887},"obj":"26317647"},{"id":"31244820-26317647-35366008","span":{"begin":911,"end":914},"obj":"26317647"}],"text":"A2BR ➣ Antagonists:\nPSB1115 (292, 315, 359, 398)\nATL-801 (399) ➣ Breast:\n4T1.2 (292, 359, 368, 399)\nE0771 (359)\n➣ Melanoma:\nB16-F10 (292, 315, 359, 398)\nLWT1 (359)\n➣ Bladder: MB49 (399) ➣ Primary tumor expansion rate ↓ (315, 398, 399)\nMature T cells (399)\nT cells (398)\nHost A2BR (399)\nHost CXCR3 (399)\nRetained in A2AR−/− mice (399)\nRetained in mice depleted of MDSCs but lost upon adoptive transfer of MDSCs (398)\n➣ Metastasis formation ↓ (292, 359, 368)\nTumor CD73 (292)\nRetained in RAG−/−cγ−/− mice lacking T cells, B cells and NK cells (292)\nRetained in mice depleted of T cells, NK cells D11c+ DCs or macrophages (359)\n➣ Survival↑ (359)\nTumor A2BR (359)\nRetained in mice depleted of T cells or NK cells (359) ↑ CD8+ T cells (315, 398)↑ CXCR3+ T cells (399)↑ NKT cells (315, 398)↓ MDSCs (315, 398)↑IFN-γ, CXCL10 mRNA (399)↑ IFN-γ, TNF-α, GzB (398)↓ MCP-1, IL-10 (398)↓ VEGF (315)↓ Microvessel density (315)"}