PMC:6537946 / 34468-35212 JSONTXT

{"project":"testtesttest","denotations":[{"id":"T601","span":{"begin":175,"end":180},"obj":"Body_part"},{"id":"T603","span":{"begin":223,"end":228},"obj":"Body_part"},{"id":"T605","span":{"begin":255,"end":260},"obj":"Body_part"},{"id":"T607","span":{"begin":616,"end":621},"obj":"Body_part"},{"id":"T608","span":{"begin":628,"end":634},"obj":"Body_part"},{"id":"T609","span":{"begin":647,"end":656},"obj":"Body_part"},{"id":"T610","span":{"begin":671,"end":676},"obj":"Body_part"},{"id":"T614","span":{"begin":694,"end":699},"obj":"Body_part"},{"id":"T616","span":{"begin":705,"end":711},"obj":"Body_part"}],"attributes":[{"id":"A601","pred":"uberon_id","subj":"T601","obj":"http://purl.obolibrary.org/obo/UBERON_0000062"},{"id":"A602","pred":"uberon_id","subj":"T601","obj":"http://purl.obolibrary.org/obo/UBERON_0003103"},{"id":"A603","pred":"uberon_id","subj":"T603","obj":"http://purl.obolibrary.org/obo/UBERON_0000062"},{"id":"A604","pred":"uberon_id","subj":"T603","obj":"http://purl.obolibrary.org/obo/UBERON_0003103"},{"id":"A605","pred":"uberon_id","subj":"T605","obj":"http://purl.obolibrary.org/obo/UBERON_0000062"},{"id":"A606","pred":"uberon_id","subj":"T605","obj":"http://purl.obolibrary.org/obo/UBERON_0003103"},{"id":"A607","pred":"uberon_id","subj":"T607","obj":"http://purl.obolibrary.org/obo/UBERON_0000178"},{"id":"A608","pred":"uberon_id","subj":"T608","obj":"http://purl.obolibrary.org/obo/UBERON_0000467"},{"id":"A609","pred":"uberon_id","subj":"T609","obj":"http://purl.obolibrary.org/obo/CL_0000738"},{"id":"A610","pred":"uberon_id","subj":"T610","obj":"http://purl.obolibrary.org/obo/UBERON_0000948"},{"id":"A611","pred":"uberon_id","subj":"T610","obj":"http://purl.obolibrary.org/obo/UBERON_0007100"},{"id":"A612","pred":"uberon_id","subj":"T610","obj":"http://purl.obolibrary.org/obo/UBERON_0015228"},{"id":"A613","pred":"uberon_id","subj":"T610","obj":"http://purl.obolibrary.org/obo/UBERON_0015230"},{"id":"A614","pred":"uberon_id","subj":"T614","obj":"http://purl.obolibrary.org/obo/UBERON_0000062"},{"id":"A615","pred":"uberon_id","subj":"T614","obj":"http://purl.obolibrary.org/obo/UBERON_0003103"},{"id":"A616","pred":"uberon_id","subj":"T616","obj":"http://purl.obolibrary.org/obo/UBERON_0000467"}],"text":"Table 2: Comparing a HTx to a VAD: benefits and limitations\nAdvantages Disadvantages Problems to solve\nHTx Benefit in terms of long-term mortality\nBetter quality of life Organ shortage\nPrecise immunomatching (HLA/ABO)\nOrgan rejection Improvement in organ allocation\nPreservation\nReducing ischaemia-reperfusion injury (e.g. OCS®)\nExpand donor pool to potentially marginal donors\nVAD ‘Unlimited’ availability Durability\nEnergy supply\nBleeding/thrombosis\nInfection\nTechnical malfunction Develop complete and durable intracorporeal devices\nTranscutaneous energy transfer\nLower bleeding/thrombosis risk\nABO: ABO blood group system; HLA: human leucocyte antigen; HTx: heart transplant; OCS: Organ Care System; VAD: ventricular assist device."}