PMC:6218602 / 21934-22668 JSONTXT

{"project":"2_test","denotations":[{"id":"30425662-22387165-41865363","span":{"begin":260,"end":262},"obj":"22387165"},{"id":"30425662-21115039-41865364","span":{"begin":264,"end":266},"obj":"21115039"},{"id":"30425662-20631176-41865365","span":{"begin":268,"end":270},"obj":"20631176"},{"id":"30425662-21035793-41865366","span":{"begin":272,"end":274},"obj":"21035793"},{"id":"30425662-19164577-41865367","span":{"begin":361,"end":363},"obj":"19164577"},{"id":"30425662-21145042-41865368","span":{"begin":365,"end":367},"obj":"21145042"},{"id":"30425662-25238608-41865369","span":{"begin":730,"end":732},"obj":"25238608"}],"text":"Functional MRI studies have also suggested abnormalities in the connectivity of brain networks in schizophrenia and relate to the structural disturbances that interconnect them. While reduced functional connectivity is a replicated finding among many studies (32, 41, 46, 47), there have also been reports of increase in functional connectivity in the illness (48, 49). The discrepancy may simply be related to non-uniform changes in brain connectivity, such as hyper-synchrony of neuronal ensembles vs. dysregulated networks, fMRI preprocessing errors, or abnormalities in neuronal wiring and oscillatory firing and compensatory hyper-connectivity of important hubs within the association cortex as a consequence of the illness (50)."}