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{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/6194691","sourcedb":"PMC","sourceid":"6194691","source_url":"https://www.ncbi.nlm.nih.gov/pmc/6194691","text":"Cutler and Sipe [301] using anaesthetized cats, Bachelard et al. [308, 309] using anaesthetized rats and Betz et al. [302] using isolated perfused dog brains all found that the influx of glucose measured using tracers could exceed the net flux by two to threefold. This is a direct, experimental demonstration that there is efflux across the blood–brain barrier that can be as large as two-thirds of the influx. This would of course be less under conditions of increased metabolic demand.","tracks":[{"project":"MyTest","denotations":[{"id":"30340614-4930133-30706243","span":{"begin":17,"end":20},"obj":"4930133"},{"id":"30340614-4144557-30706244","span":{"begin":71,"end":74},"obj":"4144557"},{"id":"30340614-4470423-30706245","span":{"begin":118,"end":121},"obj":"4470423"}],"namespaces":[{"prefix":"_base","uri":"https://www.uniprot.org/uniprot/testbase"},{"prefix":"UniProtKB","uri":"https://www.uniprot.org/uniprot/"},{"prefix":"uniprot","uri":"https://www.uniprot.org/uniprotkb/"}],"attributes":[{"subj":"30340614-4930133-30706243","pred":"source","obj":"MyTest"},{"subj":"30340614-4144557-30706244","pred":"source","obj":"MyTest"},{"subj":"30340614-4470423-30706245","pred":"source","obj":"MyTest"}]},{"project":"2_test","denotations":[{"id":"30340614-4930133-30706243","span":{"begin":17,"end":20},"obj":"4930133"},{"id":"30340614-4144557-30706244","span":{"begin":71,"end":74},"obj":"4144557"},{"id":"30340614-4470423-30706245","span":{"begin":118,"end":121},"obj":"4470423"}],"attributes":[{"subj":"30340614-4930133-30706243","pred":"source","obj":"2_test"},{"subj":"30340614-4144557-30706244","pred":"source","obj":"2_test"},{"subj":"30340614-4470423-30706245","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"MyTest","color":"#cd93ec","default":true},{"id":"2_test","color":"#93ecb3"}]}]}}