PMC:6194691 / 197586-198273 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/6194691","sourcedb":"PMC","sourceid":"6194691","source_url":"https://www.ncbi.nlm.nih.gov/pmc/6194691","text":"Because the amount of a substance is usually much easier to measure than its free concentration, what is reported in studies of elimination is frequently not clearance but rather the rate constant for elimination, k, defined as15 k=Relim/Nwhere N is the amount present in the region and Relim is now the rate of elimination from that region. If the units of rate of elimination are mol min−1 g−1 and those of amount are just mol g−1, the units of the rate constant are min−1. Strictly for Eq. 15 to apply, N must be the amount that can become free as the free concentration is reduced—i.e. it should not include forms that are irreversibly bound, aggregated, or sequestered inside cells.","divisions":[{"label":"label","span":{"begin":227,"end":229}}],"tracks":[]}