PMC:6194691 / 163186-163747 JSONTXT

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    2_test

    There are several substances whose ISF concentrations must be kept within narrow limits to ensure correct neuronal function. Na+, Cl− and K+ are good examples. Regulation of Na+ and Cl− amounts and concentrations is inextricably linked to the control of extracellular fluid volume and intracranial pressure and is outside the scope of this review (for some discussion see [41]). The control of K+ and HCO3− ISF concentrations was considered in [4]. The following sections consider the general principles and the control of ISF concentrations of CO2 and glucose.

    MyTest

    There are several substances whose ISF concentrations must be kept within narrow limits to ensure correct neuronal function. Na+, Cl− and K+ are good examples. Regulation of Na+ and Cl− amounts and concentrations is inextricably linked to the control of extracellular fluid volume and intracranial pressure and is outside the scope of this review (for some discussion see [41]). The control of K+ and HCO3− ISF concentrations was considered in [4]. The following sections consider the general principles and the control of ISF concentrations of CO2 and glucose.