PMC:6194691 / 144551-145067
Annnotations
{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/6194691","sourcedb":"PMC","sourceid":"6194691","source_url":"https://www.ncbi.nlm.nih.gov/pmc/6194691","text":"In the young, Aβ is present in soluble form and is eliminated as rapidly as it is produced with about 7–8% of the total soluble Aβ being replaced each hour [422, 444]. Monomeric and small oligomeric forms of soluble Aβ are cleared from ISF by at least four routes: incorporation into plaques, metabolism [445–451], efflux across the blood–brain barrier [62, 429, 452–454] and efflux via perivascular routes [25, 85, 128, 455]. The relative importance of each of these routes remains controversial [52, 146, 456–458].","tracks":[{"project":"MyTest","denotations":[{"id":"30340614-21148344-30706463","span":{"begin":157,"end":160},"obj":"21148344"},{"id":"30340614-16799555-30706464","span":{"begin":162,"end":165},"obj":"16799555"},{"id":"30340614-10655101-30706465","span":{"begin":305,"end":308},"obj":"10655101"},{"id":"30340614-12417655-30706465","span":{"begin":305,"end":308},"obj":"12417655"},{"id":"30340614-16457902-30706465","span":{"begin":305,"end":308},"obj":"16457902"},{"id":"30340614-19339974-30706465","span":{"begin":305,"end":308},"obj":"19339974"},{"id":"30340614-22675659-30706465","span":{"begin":305,"end":308},"obj":"22675659"},{"id":"30340614-24305823-30706465","span":{"begin":305,"end":308},"obj":"24305823"},{"id":"30340614-27458370-30706465","span":{"begin":305,"end":308},"obj":"27458370"},{"id":"30340614-11120756-30706466","span":{"begin":354,"end":356},"obj":"11120756"},{"id":"30340614-17077814-30706467","span":{"begin":358,"end":361},"obj":"17077814"},{"id":"30340614-26005850-30706468","span":{"begin":363,"end":366},"obj":"26005850"},{"id":"30340614-26619118-30706468","span":{"begin":363,"end":366},"obj":"26619118"},{"id":"30340614-26705676-30706468","span":{"begin":363,"end":366},"obj":"26705676"},{"id":"30340614-19794399-30706469","span":{"begin":412,"end":414},"obj":"19794399"},{"id":"30340614-24136970-30706470","span":{"begin":416,"end":419},"obj":"24136970"},{"id":"30340614-27234656-30706471","span":{"begin":421,"end":424},"obj":"27234656"},{"id":"30340614-26195256-30706472","span":{"begin":498,"end":500},"obj":"26195256"},{"id":"30340614-24904407-30706473","span":{"begin":507,"end":510},"obj":"24904407"},{"id":"30340614-25205593-30706473","span":{"begin":507,"end":510},"obj":"25205593"},{"id":"30340614-26236233-30706473","span":{"begin":507,"end":510},"obj":"26236233"}],"namespaces":[{"prefix":"_base","uri":"https://www.uniprot.org/uniprot/testbase"},{"prefix":"UniProtKB","uri":"https://www.uniprot.org/uniprot/"},{"prefix":"uniprot","uri":"https://www.uniprot.org/uniprotkb/"}],"attributes":[{"subj":"30340614-21148344-30706463","pred":"source","obj":"MyTest"},{"subj":"30340614-16799555-30706464","pred":"source","obj":"MyTest"},{"subj":"30340614-10655101-30706465","pred":"source","obj":"MyTest"},{"subj":"30340614-12417655-30706465","pred":"source","obj":"MyTest"},{"subj":"30340614-16457902-30706465","pred":"source","obj":"MyTest"},{"subj":"30340614-19339974-30706465","pred":"source","obj":"MyTest"},{"subj":"30340614-22675659-30706465","pred":"source","obj":"MyTest"},{"subj":"30340614-24305823-30706465","pred":"source","obj":"MyTest"},{"subj":"30340614-27458370-30706465","pred":"source","obj":"MyTest"},{"subj":"30340614-11120756-30706466","pred":"source","obj":"MyTest"},{"subj":"30340614-17077814-30706467","pred":"source","obj":"MyTest"},{"subj":"30340614-26005850-30706468","pred":"source","obj":"MyTest"},{"subj":"30340614-26619118-30706468","pred":"source","obj":"MyTest"},{"subj":"30340614-26705676-30706468","pred":"source","obj":"MyTest"},{"subj":"30340614-19794399-30706469","pred":"source","obj":"MyTest"},{"subj":"30340614-24136970-30706470","pred":"source","obj":"MyTest"},{"subj":"30340614-27234656-30706471","pred":"source","obj":"MyTest"},{"subj":"30340614-26195256-30706472","pred":"source","obj":"MyTest"},{"subj":"30340614-24904407-30706473","pred":"source","obj":"MyTest"},{"subj":"30340614-25205593-30706473","pred":"source","obj":"MyTest"},{"subj":"30340614-26236233-30706473","pred":"source","obj":"MyTest"}]},{"project":"2_test","denotations":[{"id":"30340614-21148344-30706463","span":{"begin":157,"end":160},"obj":"21148344"},{"id":"30340614-16799555-30706464","span":{"begin":162,"end":165},"obj":"16799555"},{"id":"30340614-10655101-30706465","span":{"begin":305,"end":308},"obj":"10655101"},{"id":"30340614-12417655-30706465","span":{"begin":305,"end":308},"obj":"12417655"},{"id":"30340614-16457902-30706465","span":{"begin":305,"end":308},"obj":"16457902"},{"id":"30340614-19339974-30706465","span":{"begin":305,"end":308},"obj":"19339974"},{"id":"30340614-22675659-30706465","span":{"begin":305,"end":308},"obj":"22675659"},{"id":"30340614-24305823-30706465","span":{"begin":305,"end":308},"obj":"24305823"},{"id":"30340614-27458370-30706465","span":{"begin":305,"end":308},"obj":"27458370"},{"id":"30340614-11120756-30706466","span":{"begin":354,"end":356},"obj":"11120756"},{"id":"30340614-17077814-30706467","span":{"begin":358,"end":361},"obj":"17077814"},{"id":"30340614-26005850-30706468","span":{"begin":363,"end":366},"obj":"26005850"},{"id":"30340614-26619118-30706468","span":{"begin":363,"end":366},"obj":"26619118"},{"id":"30340614-26705676-30706468","span":{"begin":363,"end":366},"obj":"26705676"},{"id":"30340614-19794399-30706469","span":{"begin":412,"end":414},"obj":"19794399"},{"id":"30340614-24136970-30706470","span":{"begin":416,"end":419},"obj":"24136970"},{"id":"30340614-27234656-30706471","span":{"begin":421,"end":424},"obj":"27234656"},{"id":"30340614-26195256-30706472","span":{"begin":498,"end":500},"obj":"26195256"},{"id":"30340614-24904407-30706473","span":{"begin":507,"end":510},"obj":"24904407"},{"id":"30340614-25205593-30706473","span":{"begin":507,"end":510},"obj":"25205593"},{"id":"30340614-26236233-30706473","span":{"begin":507,"end":510},"obj":"26236233"}],"attributes":[{"subj":"30340614-21148344-30706463","pred":"source","obj":"2_test"},{"subj":"30340614-16799555-30706464","pred":"source","obj":"2_test"},{"subj":"30340614-10655101-30706465","pred":"source","obj":"2_test"},{"subj":"30340614-12417655-30706465","pred":"source","obj":"2_test"},{"subj":"30340614-16457902-30706465","pred":"source","obj":"2_test"},{"subj":"30340614-19339974-30706465","pred":"source","obj":"2_test"},{"subj":"30340614-22675659-30706465","pred":"source","obj":"2_test"},{"subj":"30340614-24305823-30706465","pred":"source","obj":"2_test"},{"subj":"30340614-27458370-30706465","pred":"source","obj":"2_test"},{"subj":"30340614-11120756-30706466","pred":"source","obj":"2_test"},{"subj":"30340614-17077814-30706467","pred":"source","obj":"2_test"},{"subj":"30340614-26005850-30706468","pred":"source","obj":"2_test"},{"subj":"30340614-26619118-30706468","pred":"source","obj":"2_test"},{"subj":"30340614-26705676-30706468","pred":"source","obj":"2_test"},{"subj":"30340614-19794399-30706469","pred":"source","obj":"2_test"},{"subj":"30340614-24136970-30706470","pred":"source","obj":"2_test"},{"subj":"30340614-27234656-30706471","pred":"source","obj":"2_test"},{"subj":"30340614-26195256-30706472","pred":"source","obj":"2_test"},{"subj":"30340614-24904407-30706473","pred":"source","obj":"2_test"},{"subj":"30340614-25205593-30706473","pred":"source","obj":"2_test"},{"subj":"30340614-26236233-30706473","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"MyTest","color":"#93ecd1","default":true},{"id":"2_test","color":"#ecb793"}]}]}}