PMC:6194691 / 13747-14264 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/6194691","sourcedb":"PMC","sourceid":"6194691","source_url":"https://www.ncbi.nlm.nih.gov/pmc/6194691","text":"Elimination thus plays a key role in maintenance of the status quo in the brain. The principles involved in balancing inputs and outputs and what is meant by “clearance” are both considered more fully in Sect. 6. The relationship between rates of elimination, clearances, permeability-area products, volumes of distribution and half-lives together with the units used are described in Appendix A. The routes of elimination and the mechanisms by which elimination is brought about are the main subjects of this review.","tracks":[]}