PMC:6174286 / 18431-19202 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/6174286","sourcedb":"PMC","sourceid":"6174286","source_url":"https://www.ncbi.nlm.nih.gov/pmc/6174286","text":"Figure 4 Characterization of Ciliary Phenotype in ARL3-Mutant Fibroblasts from Family 2\n(A and C) Affected and control fibroblasts were observed under high-power immunofluorescence for determining ciliary expression of (A) INPP5E and (C) NPHP3. Cilia were localized with anti-ARL13B (red) and anti-PERICENTRIN (magenta) for the identification of the ciliary membrane and the base of cilia, respectively. Scale bars, 10 μm.\n(B) Quantification of ciliary localization of INPP5E (∗∗p \u003c 0.0001, unpaired t test, n \u003e 150 cilia for each group). Total cilia INPP5E in control fibroblast (II:3) cilia is higher than in heterozygous fibroblast (I:1 and II:2) cilia.\n(D) Quantification of ciliary localization of NPHP3 (∗∗p \u003c 0.0001, unpaired t test, n \u003e 150 cilia for each group).","divisions":[{"label":"label","span":{"begin":0,"end":8}},{"label":"p","span":{"begin":9,"end":87}},{"label":"p","span":{"begin":88,"end":422}},{"label":"p","span":{"begin":423,"end":656}}],"tracks":[]}