PMC:6019327 / 82091-82701 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/6019327","sourcedb":"PMC","sourceid":"6019327","source_url":"https://www.ncbi.nlm.nih.gov/pmc/6019327","text":"OSA is caused by repeated upper airway collapse leading to oxygen desaturation and disrupted sleep. Pathogenesis varies; predisposing factors include small upper airway lumen, unstable respiratory control, low arousal threshold, and dysfunctional upper airway dilator muscles. Risk factors include obesity, male sex, age, menopause, fluid retention, adenotonsillar hypertrophy, and smoking. Continuous positive airway pressure (CPAP) is the treatment of choice for OSA, with adherence of 60%–70%. The positive pressure keeps the pharyngeal area from collapsing, and thus helps alleviate the airway obstruction.","tracks":[]}