PMC:6019327 / 380011-380684 JSONTXT

{"project":"2_test","denotations":[{"id":"28506916-27029350-29308911","span":{"begin":162,"end":165},"obj":"27029350"},{"id":"28506916-27029350-29308911","span":{"begin":162,"end":165},"obj":"27029350"},{"id":"T23771","span":{"begin":162,"end":165},"obj":"27029350"},{"id":"T56143","span":{"begin":162,"end":165},"obj":"27029350"},{"id":"T93116","span":{"begin":162,"end":165},"obj":"27029350"},{"id":"T82275","span":{"begin":162,"end":165},"obj":"27029350"}],"text":"One small, prospective, multicenter randomized study was performed to evaluate whether catheter ablation is superior to AAD in patients with HF and persistent AF.529 The main goal of the ablation procedure was PV antrum isolation and LA posterior wall isolation. The results showed that catheter ablation was superior to amiodarone in achieving freedom from AF at the long-term follow-up (70% vs 34%, P \u003c.001). Moreover, ablation improved QOL and exercise capacity, and reduced hospitalization (31% vs 57%, P \u003c.001) and mortality (8% vs 18%, P =.037). These data provide some support for the notion of AF ablation as first-line therapy; however, further studies are needed."}