PMC:5985360 / 6230-7011 JSONTXT

{"project":"2_test","denotations":[{"id":"29526279-23696374-2046640","span":{"begin":120,"end":122},"obj":"23696374"},{"id":"29526279-19648217-2046641","span":{"begin":174,"end":177},"obj":"19648217"},{"id":"29526279-28484253-2046642","span":{"begin":224,"end":226},"obj":"28484253"}],"text":"African Ancestry\nWe used YFitter to call Y chromosome haplogroups30 and HaploFind to call mitochondrial DNA haplogroups.31 We used projection analysis in ADMIXTURE version 1.332 with a reference panel of 21 global ancestries33 to analyze autosomal ancestry. To determine standard errors for the proportions of ancestral components for each individual, we reran ADMIXTURE with the addition of 200 bootstrap replicates. Accounting for both within and between individual variances, we calculated the proportions for average ancestry by using inverse variance weights. We then calculated 95% confidence intervals for each ancestry and individual, zeroed out any average proportions for which the 95% confidence intervals included 0, and renormalized the remaining averages to sum to 1."}