PMC:5848821 / 18578-21256 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/5848821","sourcedb":"PMC","sourceid":"5848821","source_url":"https://www.ncbi.nlm.nih.gov/pmc/5848821","text":"Table 3 Univariable and multivariable analysis\nUnivariable Multivariable\n95% CI 95% CI\nHR P-value Lower Upper HR P-value Lower Upper\nOverall survival\n Sex (male) 1.508 0.322 0.669 3.397 2.438 0.092 0.865 6.871\n Age (continuous) 1.026 0.161 0.990 1.063 1.017 0.395 0.978 1.058\n Myasthenia gravis (yes) 0.234 0.019 0.069 0.790 0.551 0.459 0.114 2.666\n TC vs thymoma 6.315 0.000 2.652 15.040 6.506 0.002 1.956 21.646\n Incomplete resection 3.916 0.001 1.727 8.882 6.696 0.003 1.944 23.060\n Pleural surgery\n  Primary pleural surgery vs pleural surgery for recurrencea 4.392 0.017 1.302 14.813 1.493 0.603 0.330 6.757\n Type of pleural surgery\n  EPP vs LP + TP 2.351 0.040 1.041 5.312 2.491 0.122 0.784 7.913\n Preoperative therapy (yes)b 3.086 0.013 1.271 7.463 1.495 0.427 0.554 4.032\n Postoperative therapy (yes)c 2.558 0.030 1.093 5.988 1.733 0.293 0.622 4.831\nCause-specific survival\n Sex (male) 1.740 0.331 0.569 5.325 3.206 0.128 0.715 14.372\n Age (continuous) 1.041 0.108 0.991 1.093 1.039 0.197 0.980 1.101\n Myasthenia gravis (yes) 0.022 0.110 0.000 2.387 0.000 0.952 0.000 171.39\n TC vs thymoma 12.129 0.000 3.867 38.044 13.144 0.001 2.726 63.370\n Incomplete resection 2.004 0.255 0.606 6.628 2.053 0.387 0.402 10.487\n Pleural surgery\n  Primary pleural surgery vs pleural surgery for recurrencea 2.198 0.239 0.593 8.130 1.213 0.836 0.194 7.576\n Type of pleural surgery\n  EPP vs LP + TP 2.301 0.155 0.729 7.265 1.063 0.934 0.252 4.488\n Preoperative therapy (yes)b 2.179 0.180 0.697 6.803 1.072 0.914 0.593 3.788\n Postoperative therapy (yes)c 2.066 0.203 0.675 6.329 1.020 0.976 0.288 3.613\nFreedom from recurrenced\n Sex (male) 1.541 0.096 0.926 2.566 1.800 0.033 1.050 3.086\n Age (continuous) 1.007 0.523 0.985 1.031 1.009 0.504 0.983 1.036\n Myasthenia gravis (yes) 0.623 0.090 0.361 1.077 0.661 0.208 0.346 1.260\n TC vs thymoma 2.748 0.006 1.330 5.676 2.442 0.027 1.106 5.388\n Pleural surgery\n  Primary pleural surgery vs pleural surgery for recurrencea 1.138 0.629 0.002 1.919 1.131 0.676 0.633 2.024\n Type of pleural Surgery\n  EPP vs LP + TP 1.491 0.165 0.849 2.618 1.467 0.241 0.773 2.784\n Preoperative therapy (yes)b 0.852 0.542 0.508 1.427 0.577 0.068 0.319 1.042\n Postoperative therapy (yes)c 0.750 0.270 0.450 1.250 0.849 0.578 0.476 1.513\nTC: thymic carcinoma; LP: local pleurectomy; TP: total pleurectomy; EPP: extrapleural pneumonectomy.\na Analysis of primary pleural surgery versus pleural surgery for recurrence.\nb Patients received (pseudo-)neoadjuvant therapy, including chemotherapy ± radiotherapy.\nc Patients received (pseudo-)adjuvant therapy, including chemotherapy ± radiotherapy.\nd Freedom from recurrence was analysed only for patients after R0 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