PMC:5777449 / 30031-30873 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/5777449","sourcedb":"PMC","sourceid":"5777449","source_url":"https://www.ncbi.nlm.nih.gov/pmc/5777449","text":"Figure 5 kiaa1109 Knockdown in Zebrafish Results in Phenotypes Reminiscent of Probands’ Clinical Features\n(A) Lateral views representing the four classes of observed phenotypes in 2 dpf TU zebrafish embryos injected with sbE4-MO (morpholino) targeting kiaa1109: from top left to bottom right, normal, hydrocephalic or other head defects, curved and curved with head defect.\n(B) Results for uninjected embryos (left) and those injected with equivalent amounts of standard control MO (center) or kiaa1109 sbE4-MO (6.7 ng, right). Phenotyping and scoring were performed at 2 dpf in two independent experiments.\n(C) Results for uninjected embryos (left) and those injected with equivalent amounts of standard control MO (center) or kiaa1109 sbE2-MO (16.9 ng, right). Phenotyping and scoring were performed at 2 dpf in two independent experiments.","tracks":[]}