PMC:55322 / 23980-26740 JSONTXT

{"target":"http://pubannotation.org/docs/sourcedb/PMC/sourceid/55322","sourcedb":"PMC","sourceid":"55322","source_url":"https://www.ncbi.nlm.nih.gov/pmc/55322","text":"Table 3 Ontological classification of 22,339 human gene products\nBiological function Number of transcripts Biological process Number of transcripts\nTranscription factor 958 (306) Carbohydrate metabolism 281 (84)\nTranslation factor 62 (27) Nucleotide and nucleic acid metabolism 173 (51)\nRNA binding 142 (41) DNA replication 240 (126)\nRibosomal protein 232 (130) Transcription 1,059 (651)\nCell cycle regulator 42 (16) RNA processing 204 (59)\nStructural protein 145 (48) Amino acid and derivative metabolism 87 (29)\nCytoskeleton structural protein 329 (181) Protein biosynthesis 264 (162)\nExtracellular matrix 361 (87) Protein modification 235 (88)\nActin binding 66 (25) Protein targeting 26 (5)\nMotor protein 245 (77) Protein degradation 136 (45)\nChaperone 87 (27) Proteolysis and peptidolysis 96 (36)\nEnzyme 2,664 (1,404) Lipid metabolism 424 (187)\nProtein kinase 895 (484) Monocarbon compound metabolism 9 (3)\nProtein kinase inhibitor 19 (12) Coenzyme and prosthetic group metabolism 92 (29)\nProtein phosphatase 43 (7) Steroid compound metabolism 40 (10)\nProtein phosphatase inhibitor 17 (3) Prostaglandin metabolism 12 (3)\nProtease 441 (255) Transport 549 (288)\nProtease inhibitor 92 (37) Electron transport 491 (273)\nEnzyme activator 18 (3) Ion transport 302 (90)\nEnzyme inhibitor 14 (4) Small molecular transport 19 (9)\nAlkyl transfer 17 (3) Neurotransmitter transport 9 (3)\nAmide transfer 15 (3) Ion homeostasis 201 (57)\nCarbonyl transfer 191 (38) Organelle organization and biogenesis 408 (254)\nHydroxyl transfer 13 (6) Nuclear organization and biogenesis 1,380 (647)\nPhosphoryl transfer 823 (281) Cytoplasm organization and biogenesis 42 (20)\nOxireduction 148 (76) Meiosis 15 (2)\nTransmembrane protein 184 (48) Mitosis 25 (6)\nReceptor 921 (478) Cell cycle 271 (100)\nG protein-linked receptor 164 (106) DNA packaging 15 (6)\nDefense/immunity protein 353 (164) DNA repair 132 (41)\nLigand binding or carrier 691 (331) DNA recombination 31 (3)\nIon channel 245 (141) Methylation 185 (53)\nOncogene 128 (42) Signal transduction 1,231 (383)\nTumor suppressor 8 (6) Growth regulation 15 (4)\nGrowth factor 95 (40) Differentiation 24 (6)\nHormone 42 (14) Apoptosis 160 (49)\nCell communication 247 (84) Angiogenesis 11 (4)\nCell adhesion 433 (252) Defense/immunity 112 (49)\nDetoxification 33 (15)\nStress response 90 (41)\nDevelopmental process 278 (99)\nNeurogenesis and regeneration 147 (43)\nPhysiological process 159 (43)\nSensory perception 292 (65)\nFunctionally classified 12,334 (5,204) Process classified 10,005 (4,225)\nEach transcriptional unit and HINT transcript (in parentheses) was assigned to a unique biological function or 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