Id |
Subject |
Object |
Predicate |
Lexical cue |
T2186 |
0-4 |
RB |
denotes |
Very |
T2187 |
5-13 |
RB |
denotes |
recently |
T2188 |
30-35 |
VBN |
denotes |
found |
T2189 |
13-15 |
, |
denotes |
, |
T2190 |
15-20 |
NN |
denotes |
Ptdsr |
T2191 |
21-24 |
VBZ |
denotes |
has |
T2192 |
25-29 |
VBN |
denotes |
been |
T2193 |
36-38 |
IN |
denotes |
in |
T2194 |
39-42 |
DT |
denotes |
the |
T2195 |
48-55 |
NN |
denotes |
nucleus |
T2196 |
43-47 |
NN |
denotes |
cell |
T2197 |
55-56 |
. |
denotes |
. |
T2198 |
56-219 |
sentence |
denotes |
Its nuclear localization is mediated by five independent nuclear localization signals, each of which alone is capable of targeting Ptdsr to the cell nucleus [29]. |
T2199 |
57-60 |
PRP$ |
denotes |
Its |
T2200 |
69-81 |
NN |
denotes |
localization |
T2201 |
61-68 |
JJ |
denotes |
nuclear |
T2202 |
85-93 |
VBN |
denotes |
mediated |
T2203 |
82-84 |
VBZ |
denotes |
is |
T2204 |
94-96 |
IN |
denotes |
by |
T2205 |
97-101 |
CD |
denotes |
five |
T2206 |
135-142 |
NNS |
denotes |
signals |
T2207 |
102-113 |
JJ |
denotes |
independent |
T2208 |
114-121 |
JJ |
denotes |
nuclear |
T2209 |
122-134 |
NN |
denotes |
localization |
T2210 |
142-144 |
, |
denotes |
, |
T2211 |
144-148 |
DT |
denotes |
each |
T2212 |
164-166 |
VBZ |
denotes |
is |
T2213 |
149-151 |
IN |
denotes |
of |
T2214 |
152-157 |
WDT |
denotes |
which |
T2215 |
158-163 |
RB |
denotes |
alone |
T2216 |
167-174 |
JJ |
denotes |
capable |
T2217 |
175-177 |
IN |
denotes |
of |
T2218 |
178-187 |
VBG |
denotes |
targeting |
T2219 |
188-193 |
NN |
denotes |
Ptdsr |
T2220 |
194-196 |
IN |
denotes |
to |
T2221 |
197-200 |
DT |
denotes |
the |
T2222 |
206-213 |
NN |
denotes |
nucleus |
T2223 |
201-205 |
NN |
denotes |
cell |
T2224 |
214-215 |
-LRB- |
denotes |
[ |
T2225 |
215-217 |
CD |
denotes |
29 |
T2226 |
217-218 |
-RRB- |
denotes |
] |
T2227 |
218-219 |
. |
denotes |
. |
T2228 |
219-348 |
sentence |
denotes |
Moreover, an additional study performed recently in Hydra showed an exclusively nuclear localization for the Ptdsr protein [30]. |
T2229 |
220-228 |
RB |
denotes |
Moreover |
T2230 |
278-284 |
VBD |
denotes |
showed |
T2231 |
228-230 |
, |
denotes |
, |
T2232 |
230-232 |
DT |
denotes |
an |
T2233 |
244-249 |
NN |
denotes |
study |
T2234 |
233-243 |
JJ |
denotes |
additional |
T2235 |
250-259 |
VBN |
denotes |
performed |
T2236 |
260-268 |
RB |
denotes |
recently |
T2237 |
269-271 |
IN |
denotes |
in |
T2238 |
272-277 |
NNP |
denotes |
Hydra |
T2239 |
285-287 |
DT |
denotes |
an |
T2240 |
308-320 |
NN |
denotes |
localization |
T2241 |
288-299 |
RB |
denotes |
exclusively |
T2242 |
300-307 |
JJ |
denotes |
nuclear |
T2243 |
321-324 |
IN |
denotes |
for |
T2244 |
325-328 |
DT |
denotes |
the |
T2245 |
335-342 |
NN |
denotes |
protein |
T2246 |
329-334 |
NN |
denotes |
Ptdsr |
T2247 |
343-344 |
-LRB- |
denotes |
[ |
T2248 |
344-346 |
CD |
denotes |
30 |
T2249 |
346-347 |
-RRB- |
denotes |
] |
T2250 |
347-348 |
. |
denotes |
. |
T2251 |
348-481 |
sentence |
denotes |
Most interestingly, the nuclear localization of Ptdsr in Hydra epithelial cells did not change upon phagocytosis of apoptotic cells. |
T2252 |
349-353 |
RBS |
denotes |
Most |
T2253 |
354-367 |
RB |
denotes |
interestingly |
T2254 |
437-443 |
VB |
denotes |
change |
T2255 |
367-369 |
, |
denotes |
, |
T2256 |
369-372 |
DT |
denotes |
the |
T2257 |
381-393 |
NN |
denotes |
localization |
T2258 |
373-380 |
JJ |
denotes |
nuclear |
T2259 |
394-396 |
IN |
denotes |
of |
T2260 |
397-402 |
NN |
denotes |
Ptdsr |
T2261 |
403-405 |
IN |
denotes |
in |
T2262 |
406-411 |
NNP |
denotes |
Hydra |
T2263 |
423-428 |
NNS |
denotes |
cells |
T2264 |
412-422 |
JJ |
denotes |
epithelial |
T2265 |
429-432 |
VBD |
denotes |
did |
T2266 |
433-436 |
RB |
denotes |
not |
T2267 |
444-448 |
IN |
denotes |
upon |
T2268 |
449-461 |
NN |
denotes |
phagocytosis |
T2269 |
462-464 |
IN |
denotes |
of |
T2270 |
465-474 |
JJ |
denotes |
apoptotic |
T2271 |
475-480 |
NNS |
denotes |
cells |
T2272 |
480-481 |
. |
denotes |
. |
T2273 |
481-660 |
sentence |
denotes |
These reports challenge the original hypothesis, according to which Ptdsr is an exclusively transmembrane receptor for apoptotic cell recognition and anti-inflammatory signaling. |
T2274 |
482-487 |
DT |
denotes |
These |
T2275 |
488-495 |
NNS |
denotes |
reports |
T2276 |
496-505 |
VBP |
denotes |
challenge |
T2277 |
506-509 |
DT |
denotes |
the |
T2278 |
519-529 |
NN |
denotes |
hypothesis |
T2279 |
510-518 |
JJ |
denotes |
original |
T2280 |
529-531 |
, |
denotes |
, |
T2281 |
531-540 |
VBG |
denotes |
according |
T2282 |
556-558 |
VBZ |
denotes |
is |
T2283 |
541-543 |
IN |
denotes |
to |
T2284 |
544-549 |
WDT |
denotes |
which |
T2285 |
550-555 |
NN |
denotes |
Ptdsr |
T2286 |
559-561 |
DT |
denotes |
an |
T2287 |
588-596 |
NN |
denotes |
receptor |
T2288 |
562-573 |
RB |
denotes |
exclusively |
T2289 |
574-587 |
JJ |
denotes |
transmembrane |
T2290 |
597-600 |
IN |
denotes |
for |
T2291 |
601-610 |
JJ |
denotes |
apoptotic |
T2292 |
611-615 |
NN |
denotes |
cell |
T2293 |
616-627 |
NN |
denotes |
recognition |
T2294 |
628-631 |
CC |
denotes |
and |
T2295 |
632-649 |
JJ |
denotes |
anti-inflammatory |
T2296 |
650-659 |
NN |
denotes |
signaling |
T2297 |
659-660 |
. |
denotes |
. |
R1094 |
T2275 |
T2276 |
nsubj |
reports,challenge |
R1096 |
T2277 |
T2278 |
det |
the,hypothesis |
R1101 |
T2278 |
T2276 |
dobj |
hypothesis,challenge |
R1105 |
T2279 |
T2278 |
amod |
original,hypothesis |
R1112 |
T2280 |
T2278 |
punct |
", ",hypothesis |
R1115 |
T2186 |
T2187 |
advmod |
Very,recently |
R1116 |
T2281 |
T2282 |
prep |
according,is |
R1117 |
T2187 |
T2188 |
advmod |
recently,found |
R1118 |
T2282 |
T2278 |
relcl |
is,hypothesis |
R1119 |
T2189 |
T2188 |
punct |
", ",found |
R1120 |
T2190 |
T2188 |
nsubjpass |
Ptdsr,found |
R1121 |
T2191 |
T2188 |
aux |
has,found |
R1122 |
T2283 |
T2281 |
prep |
to,according |
R1123 |
T2192 |
T2188 |
auxpass |
been,found |
R1124 |
T2193 |
T2188 |
prep |
in,found |
R1125 |
T2194 |
T2195 |
det |
the,nucleus |
R1126 |
T2284 |
T2283 |
pobj |
which,to |
R1127 |
T2285 |
T2282 |
nsubj |
Ptdsr,is |
R1128 |
T2195 |
T2193 |
pobj |
nucleus,in |
R1129 |
T2196 |
T2195 |
compound |
cell,nucleus |
R1130 |
T2286 |
T2287 |
det |
an,receptor |
R1131 |
T2197 |
T2188 |
punct |
.,found |
R1132 |
T2199 |
T2200 |
poss |
Its,localization |
R1133 |
T2287 |
T2282 |
attr |
receptor,is |
R1134 |
T2200 |
T2202 |
nsubjpass |
localization,mediated |
R1135 |
T2201 |
T2200 |
amod |
nuclear,localization |
R1136 |
T2288 |
T2289 |
advmod |
exclusively,transmembrane |
R1137 |
T2203 |
T2202 |
auxpass |
is,mediated |
R1138 |
T2204 |
T2202 |
agent |
by,mediated |
R1139 |
T2289 |
T2287 |
amod |
transmembrane,receptor |
R1140 |
T2205 |
T2206 |
nummod |
five,signals |
R1141 |
T2206 |
T2204 |
pobj |
signals,by |
R1142 |
T2290 |
T2287 |
prep |
for,receptor |
R1143 |
T2207 |
T2206 |
amod |
independent,signals |
R1144 |
T2208 |
T2209 |
amod |
nuclear,localization |
R1145 |
T2209 |
T2206 |
compound |
localization,signals |
R1146 |
T2291 |
T2292 |
amod |
apoptotic,cell |
R1147 |
T2210 |
T2206 |
punct |
", ",signals |
R1148 |
T2211 |
T2212 |
dep |
each,is |
R1149 |
T2212 |
T2206 |
relcl |
is,signals |
R1150 |
T2292 |
T2293 |
compound |
cell,recognition |
R1151 |
T2213 |
T2211 |
prep |
of,each |
R1152 |
T2214 |
T2213 |
pobj |
which,of |
R1153 |
T2215 |
T2211 |
advmod |
alone,each |
R1154 |
T2293 |
T2290 |
pobj |
recognition,for |
R1155 |
T2216 |
T2212 |
acomp |
capable,is |
R1156 |
T2217 |
T2216 |
prep |
of,capable |
R1157 |
T2218 |
T2217 |
pcomp |
targeting,of |
R1158 |
T2294 |
T2293 |
cc |
and,recognition |
R1159 |
T2219 |
T2218 |
dobj |
Ptdsr,targeting |
R1160 |
T2220 |
T2218 |
prep |
to,targeting |
R1161 |
T2221 |
T2222 |
det |
the,nucleus |
R1162 |
T2222 |
T2220 |
pobj |
nucleus,to |
R1163 |
T2223 |
T2222 |
compound |
cell,nucleus |
R1164 |
T2295 |
T2296 |
amod |
anti-inflammatory,signaling |
R1165 |
T2224 |
T2225 |
punct |
[,29 |
R1166 |
T2225 |
T2202 |
parataxis |
29,mediated |
R1167 |
T2226 |
T2225 |
punct |
],29 |
R1168 |
T2227 |
T2202 |
punct |
.,mediated |
R1169 |
T2296 |
T2293 |
conj |
signaling,recognition |
R1170 |
T2229 |
T2230 |
advmod |
Moreover,showed |
R1171 |
T2297 |
T2276 |
punct |
.,challenge |
R1172 |
T2231 |
T2230 |
punct |
", ",showed |
R1173 |
T2232 |
T2233 |
det |
an,study |
R1175 |
T2233 |
T2230 |
nsubj |
study,showed |
R1176 |
T2234 |
T2233 |
amod |
additional,study |
R1177 |
T2235 |
T2233 |
acl |
performed,study |
R1179 |
T2236 |
T2235 |
advmod |
recently,performed |
R1180 |
T2237 |
T2235 |
prep |
in,performed |
R1182 |
T2238 |
T2237 |
pobj |
Hydra,in |
R1183 |
T2239 |
T2240 |
det |
an,localization |
R1184 |
T2240 |
T2230 |
dobj |
localization,showed |
R1185 |
T2241 |
T2242 |
advmod |
exclusively,nuclear |
R1187 |
T2242 |
T2240 |
amod |
nuclear,localization |
R1188 |
T2243 |
T2240 |
prep |
for,localization |
R1189 |
T2244 |
T2245 |
det |
the,protein |
R1191 |
T2245 |
T2243 |
pobj |
protein,for |
R1192 |
T2246 |
T2245 |
compound |
Ptdsr,protein |
R1194 |
T2247 |
T2248 |
punct |
[,30 |
R1195 |
T2248 |
T2230 |
parataxis |
30,showed |
R1196 |
T2249 |
T2248 |
punct |
],30 |
R1198 |
T2250 |
T2230 |
punct |
.,showed |
R1199 |
T2252 |
T2253 |
advmod |
Most,interestingly |
R1201 |
T2253 |
T2254 |
advmod |
interestingly,change |
R1202 |
T2255 |
T2254 |
punct |
", ",change |
R1204 |
T2256 |
T2257 |
det |
the,localization |
R1205 |
T2257 |
T2254 |
nsubj |
localization,change |
R1206 |
T2258 |
T2257 |
amod |
nuclear,localization |
R1207 |
T2259 |
T2257 |
prep |
of,localization |
R1209 |
T2260 |
T2259 |
pobj |
Ptdsr,of |
R1210 |
T2261 |
T2257 |
prep |
in,localization |
R1211 |
T2262 |
T2263 |
nmod |
Hydra,cells |
R1212 |
T2263 |
T2261 |
pobj |
cells,in |
R1213 |
T2264 |
T2263 |
amod |
epithelial,cells |
R1214 |
T2265 |
T2254 |
aux |
did,change |
R1216 |
T2266 |
T2254 |
neg |
not,change |
R1217 |
T2267 |
T2254 |
prep |
upon,change |
R1218 |
T2268 |
T2267 |
pobj |
phagocytosis,upon |
R1220 |
T2269 |
T2268 |
prep |
of,phagocytosis |
R1221 |
T2270 |
T2271 |
amod |
apoptotic,cells |
R1222 |
T2271 |
T2269 |
pobj |
cells,of |
R1224 |
T2272 |
T2254 |
punct |
.,change |
R1226 |
T2274 |
T2275 |
det |
These,reports |