Id |
Subject |
Object |
Predicate |
Lexical cue |
T11506 |
0-2 |
IN |
denotes |
In |
T11507 |
24-35 |
VBP |
denotes |
demonstrate |
T11508 |
3-10 |
NN |
denotes |
summary |
T11509 |
10-12 |
, |
denotes |
, |
T11510 |
12-15 |
PRP$ |
denotes |
our |
T11511 |
16-23 |
NNS |
denotes |
studies |
T11512 |
36-40 |
IN |
denotes |
that |
T11513 |
50-58 |
VBN |
denotes |
required |
T11514 |
41-46 |
NN |
denotes |
Ptdsr |
T11515 |
47-49 |
VBZ |
denotes |
is |
T11516 |
59-62 |
IN |
denotes |
for |
T11517 |
63-69 |
JJ |
denotes |
normal |
T11518 |
77-92 |
NN |
denotes |
differentiation |
T11519 |
70-76 |
NN |
denotes |
tissue |
T11520 |
92-94 |
, |
denotes |
, |
T11521 |
94-104 |
RB |
denotes |
especially |
T11522 |
105-111 |
IN |
denotes |
during |
T11523 |
112-115 |
DT |
denotes |
the |
T11524 |
130-136 |
NN |
denotes |
period |
T11525 |
116-129 |
NN |
denotes |
mid-gestation |
T11526 |
137-141 |
WRB |
denotes |
when |
T11527 |
145-153 |
VBD |
denotes |
observed |
T11528 |
142-144 |
PRP |
denotes |
we |
T11529 |
154-157 |
DT |
denotes |
the |
T11530 |
186-192 |
NNS |
denotes |
delays |
T11531 |
158-162 |
RBS |
denotes |
most |
T11532 |
163-169 |
JJ |
denotes |
severe |
T11533 |
170-185 |
NN |
denotes |
differentiation |
T11534 |
193-195 |
IN |
denotes |
in |
T11535 |
196-203 |
JJ |
denotes |
several |
T11536 |
204-210 |
NNS |
denotes |
organs |
T11537 |
211-213 |
IN |
denotes |
of |
T11538 |
214-219 |
NN |
denotes |
Ptdsr |
T11539 |
220-228 |
NN |
denotes |
knockout |
T11540 |
219-220 |
HYPH |
denotes |
- |
T11541 |
229-233 |
NNS |
denotes |
mice |
T11542 |
233-234 |
. |
denotes |
. |
T11543 |
234-395 |
sentence |
denotes |
The multiple defects in tissue differentiation cannot be explained by failure of apoptotic cell clearance, as this process is normal in our Ptdsr-knockout line. |
T11544 |
235-238 |
DT |
denotes |
The |
T11545 |
248-255 |
NNS |
denotes |
defects |
T11546 |
239-247 |
JJ |
denotes |
multiple |
T11547 |
292-301 |
VBN |
denotes |
explained |
T11548 |
256-258 |
IN |
denotes |
in |
T11549 |
259-265 |
NN |
denotes |
tissue |
T11550 |
266-281 |
NN |
denotes |
differentiation |
T11551 |
282-285 |
MD |
denotes |
can |
T11552 |
285-288 |
RB |
denotes |
not |
T11553 |
289-291 |
VB |
denotes |
be |
T11554 |
302-304 |
IN |
denotes |
by |
T11555 |
305-312 |
NN |
denotes |
failure |
T11556 |
313-315 |
IN |
denotes |
of |
T11557 |
316-325 |
JJ |
denotes |
apoptotic |
T11558 |
331-340 |
NN |
denotes |
clearance |
T11559 |
326-330 |
NN |
denotes |
cell |
T11560 |
340-342 |
, |
denotes |
, |
T11561 |
342-344 |
IN |
denotes |
as |
T11562 |
358-360 |
VBZ |
denotes |
is |
T11563 |
345-349 |
DT |
denotes |
this |
T11564 |
350-357 |
NN |
denotes |
process |
T11565 |
361-367 |
JJ |
denotes |
normal |
T11566 |
368-370 |
IN |
denotes |
in |
T11567 |
371-374 |
PRP$ |
denotes |
our |
T11568 |
390-394 |
NN |
denotes |
line |
T11569 |
375-380 |
NN |
denotes |
Ptdsr |
T11570 |
381-389 |
NN |
denotes |
knockout |
T11571 |
380-381 |
HYPH |
denotes |
- |
T11572 |
394-395 |
. |
denotes |
. |
T11573 |
395-538 |
sentence |
denotes |
This result therefore indicates that Ptdsr has a novel, hitherto unexpected, role in promoting tissue maturation and terminal differentiation. |
T11574 |
396-400 |
DT |
denotes |
This |
T11575 |
401-407 |
NN |
denotes |
result |
T11609 |
623-634 |
VB |
denotes |
investigate |
T11610 |
635-638 |
DT |
denotes |
the |
T11611 |
639-643 |
NN |
denotes |
role |
T11612 |
644-646 |
IN |
denotes |
of |
T11613 |
647-654 |
JJ |
denotes |
spatial |
T11614 |
674-684 |
NN |
denotes |
expression |
T11615 |
655-658 |
CC |
denotes |
and |
T11616 |
659-667 |
JJ |
denotes |
temporal |
T11617 |
668-673 |
NN |
denotes |
Ptdsr |
T11618 |
685-688 |
CC |
denotes |
and |
T11619 |
689-697 |
NN |
denotes |
function |
T11620 |
698-704 |
IN |
denotes |
during |
T11621 |
705-711 |
NN |
denotes |
tissue |
T11622 |
712-727 |
NN |
denotes |
differentiation |
T11623 |
727-728 |
. |
denotes |
. |
T11576 |
418-427 |
VBZ |
denotes |
indicates |
T11577 |
408-417 |
RB |
denotes |
therefore |
T11578 |
428-432 |
IN |
denotes |
that |
T11579 |
439-442 |
VBZ |
denotes |
has |
T11580 |
433-438 |
NN |
denotes |
Ptdsr |
T11581 |
443-444 |
DT |
denotes |
a |
T11582 |
473-477 |
NN |
denotes |
role |
T11583 |
445-450 |
JJ |
denotes |
novel |
T11584 |
450-452 |
, |
denotes |
, |
T11585 |
452-460 |
RB |
denotes |
hitherto |
T11586 |
461-471 |
JJ |
denotes |
unexpected |
T11587 |
471-473 |
, |
denotes |
, |
T11588 |
478-480 |
IN |
denotes |
in |
T11589 |
481-490 |
VBG |
denotes |
promoting |
T11590 |
491-497 |
NN |
denotes |
tissue |
T11591 |
498-508 |
NN |
denotes |
maturation |
T11592 |
509-512 |
CC |
denotes |
and |
T11593 |
513-521 |
JJ |
denotes |
terminal |
T11594 |
522-537 |
NN |
denotes |
differentiation |
T11595 |
537-538 |
. |
denotes |
. |
T11596 |
538-728 |
sentence |
denotes |
Additional studies with conditionally targeted Ptdsr-deficient mice are required to investigate the role of spatial and temporal Ptdsr expression and function during tissue differentiation. |
T11597 |
539-549 |
JJ |
denotes |
Additional |
T11598 |
550-557 |
NNS |
denotes |
studies |
T11599 |
611-619 |
VBN |
denotes |
required |
T11600 |
558-562 |
IN |
denotes |
with |
T11601 |
563-576 |
RB |
denotes |
conditionally |
T11602 |
577-585 |
VBN |
denotes |
targeted |
T11603 |
602-606 |
NNS |
denotes |
mice |
T11604 |
586-591 |
NN |
denotes |
Ptdsr |
T11605 |
592-601 |
JJ |
denotes |
deficient |
T11606 |
591-592 |
HYPH |
denotes |
- |
T11607 |
607-610 |
VBP |
denotes |
are |
T11608 |
620-622 |
TO |
denotes |
to |
R6871 |
T11506 |
T11507 |
prep |
In,demonstrate |
R6872 |
T11508 |
T11506 |
pobj |
summary,In |
R6874 |
T11509 |
T11507 |
punct |
", ",demonstrate |
R6875 |
T11510 |
T11511 |
poss |
our,studies |
R6876 |
T11511 |
T11507 |
nsubj |
studies,demonstrate |
R6878 |
T11512 |
T11513 |
mark |
that,required |
R6879 |
T11513 |
T11507 |
ccomp |
required,demonstrate |
R6880 |
T11514 |
T11513 |
nsubjpass |
Ptdsr,required |
R6882 |
T11515 |
T11513 |
auxpass |
is,required |
R6883 |
T11516 |
T11513 |
prep |
for,required |
R6884 |
T11517 |
T11518 |
amod |
normal,differentiation |
R6886 |
T11518 |
T11516 |
pobj |
differentiation,for |
R6887 |
T11519 |
T11518 |
compound |
tissue,differentiation |
R6889 |
T11520 |
T11513 |
punct |
", ",required |
R6890 |
T11521 |
T11522 |
advmod |
especially,during |
R6891 |
T11522 |
T11513 |
prep |
during,required |
R6893 |
T11523 |
T11524 |
det |
the,period |
R6894 |
T11524 |
T11522 |
pobj |
period,during |
R6895 |
T11525 |
T11524 |
compound |
mid-gestation,period |
R6897 |
T11526 |
T11527 |
advmod |
when,observed |
R6898 |
T11527 |
T11524 |
relcl |
observed,period |
R6899 |
T11528 |
T11527 |
nsubj |
we,observed |
R6901 |
T11529 |
T11530 |
det |
the,delays |
R6902 |
T11530 |
T11527 |
dobj |
delays,observed |
R6903 |
T11531 |
T11532 |
advmod |
most,severe |
R6905 |
T11532 |
T11530 |
amod |
severe,delays |
R6906 |
T11533 |
T11530 |
compound |
differentiation,delays |
R6908 |
T11534 |
T11527 |
prep |
in,observed |
R6909 |
T11535 |
T11536 |
amod |
several,organs |
R6910 |
T11536 |
T11534 |
pobj |
organs,in |
R6912 |
T11537 |
T11536 |
prep |
of,organs |
R6913 |
T11538 |
T11539 |
compound |
Ptdsr,knockout |
R6915 |
T11539 |
T11541 |
compound |
knockout,mice |
R6916 |
T11540 |
T11539 |
punct |
-,knockout |
R6917 |
T11541 |
T11537 |
pobj |
mice,of |
R6918 |
T11542 |
T11507 |
punct |
.,demonstrate |
R6920 |
T11544 |
T11545 |
det |
The,defects |
R6921 |
T11545 |
T11547 |
nsubjpass |
defects,explained |
R6922 |
T11546 |
T11545 |
amod |
multiple,defects |
R6924 |
T11548 |
T11545 |
prep |
in,defects |
R6925 |
T11549 |
T11550 |
compound |
tissue,differentiation |
R6927 |
T11550 |
T11548 |
pobj |
differentiation,in |
R6928 |
T11551 |
T11547 |
aux |
can,explained |
R6929 |
T11552 |
T11547 |
neg |
not,explained |
R6931 |
T11553 |
T11547 |
auxpass |
be,explained |
R6932 |
T11554 |
T11547 |
agent |
by,explained |
R6934 |
T11555 |
T11554 |
pobj |
failure,by |
R6935 |
T11556 |
T11555 |
prep |
of,failure |
R6936 |
T11557 |
T11558 |
amod |
apoptotic,clearance |
R6938 |
T11558 |
T11556 |
pobj |
clearance,of |
R6939 |
T11559 |
T11558 |
compound |
cell,clearance |
R6941 |
T11560 |
T11547 |
punct |
", ",explained |
R6942 |
T11561 |
T11562 |
mark |
as,is |
R6943 |
T11562 |
T11547 |
advcl |
is,explained |
R6945 |
T11563 |
T11564 |
det |
this,process |
R6946 |
T11564 |
T11562 |
nsubj |
process,is |
R6986 |
T11592 |
T11591 |
cc |
and,maturation |
R6987 |
T11593 |
T11594 |
amod |
terminal,differentiation |
R6988 |
T11594 |
T11591 |
conj |
differentiation,maturation |
R6989 |
T11595 |
T11576 |
punct |
.,indicates |
R6990 |
T11597 |
T11598 |
amod |
Additional,studies |
R6991 |
T11598 |
T11599 |
nsubjpass |
studies,required |
R6992 |
T11600 |
T11598 |
prep |
with,studies |
R6993 |
T11601 |
T11602 |
advmod |
conditionally,targeted |
R6994 |
T11602 |
T11603 |
amod |
targeted,mice |
R6995 |
T11603 |
T11600 |
pobj |
mice,with |
R6996 |
T11604 |
T11605 |
npadvmod |
Ptdsr,deficient |
R6997 |
T11605 |
T11603 |
amod |
deficient,mice |
R6998 |
T11606 |
T11605 |
punct |
-,deficient |
R6999 |
T11607 |
T11599 |
auxpass |
are,required |
R7000 |
T11608 |
T11609 |
aux |
to,investigate |
R7001 |
T11609 |
T11599 |
advcl |
investigate,required |
R7002 |
T11610 |
T11611 |
det |
the,role |
R7003 |
T11611 |
T11609 |
dobj |
role,investigate |
R7004 |
T11612 |
T11611 |
prep |
of,role |
R7005 |
T11613 |
T11614 |
amod |
spatial,expression |
R7006 |
T11614 |
T11612 |
pobj |
expression,of |
R7007 |
T11615 |
T11613 |
cc |
and,spatial |
R7008 |
T11616 |
T11613 |
conj |
temporal,spatial |
R7009 |
T11617 |
T11614 |
compound |
Ptdsr,expression |
R7010 |
T11618 |
T11614 |
cc |
and,expression |
R7011 |
T11619 |
T11614 |
conj |
function,expression |
R7012 |
T11620 |
T11611 |
prep |
during,role |
R7013 |
T11621 |
T11622 |
compound |
tissue,differentiation |
R7014 |
T11622 |
T11620 |
pobj |
differentiation,during |
R7015 |
T11623 |
T11599 |
punct |
.,required |
R6949 |
T11565 |
T11562 |
acomp |
normal,is |
R6951 |
T11566 |
T11562 |
prep |
in,is |
R6952 |
T11567 |
T11568 |
poss |
our,line |
R6953 |
T11568 |
T11566 |
pobj |
line,in |
R6955 |
T11569 |
T11570 |
compound |
Ptdsr,knockout |
R6956 |
T11570 |
T11568 |
compound |
knockout,line |
R6958 |
T11571 |
T11570 |
punct |
-,knockout |
R6959 |
T11572 |
T11547 |
punct |
.,explained |
R6961 |
T11574 |
T11575 |
det |
This,result |
R6962 |
T11575 |
T11576 |
nsubj |
result,indicates |
R6968 |
T11577 |
T11576 |
advmod |
therefore,indicates |
R6969 |
T11578 |
T11579 |
mark |
that,has |
R6970 |
T11579 |
T11576 |
ccomp |
has,indicates |
R6972 |
T11580 |
T11579 |
nsubj |
Ptdsr,has |
R6973 |
T11581 |
T11582 |
det |
a,role |
R6974 |
T11582 |
T11579 |
dobj |
role,has |
R6975 |
T11583 |
T11582 |
amod |
novel,role |
R6977 |
T11584 |
T11582 |
punct |
", ",role |
R6978 |
T11585 |
T11586 |
advmod |
hitherto,unexpected |
R6980 |
T11586 |
T11582 |
amod |
unexpected,role |
R6981 |
T11587 |
T11582 |
punct |
", ",role |
R6982 |
T11588 |
T11582 |
prep |
in,role |
R6983 |
T11589 |
T11588 |
pcomp |
promoting,in |
R6984 |
T11590 |
T11591 |
compound |
tissue,maturation |
R6985 |
T11591 |
T11589 |
dobj |
maturation,promoting |