Id |
Subject |
Object |
Predicate |
Lexical cue |
T340 |
330-348 |
NN |
denotes |
phosphatidylserine |
T286 |
0-10 |
sentence |
denotes |
Background |
T287 |
0-10 |
NN |
denotes |
Background |
T288 |
10-122 |
sentence |
denotes |
Phagocytosis of apoptotic cells is fundamental to animal development, immune function and cellular homeostasis. |
T289 |
11-23 |
NN |
denotes |
Phagocytosis |
T290 |
43-45 |
VBZ |
denotes |
is |
T291 |
24-26 |
IN |
denotes |
of |
T292 |
27-36 |
JJ |
denotes |
apoptotic |
T293 |
37-42 |
NNS |
denotes |
cells |
T294 |
46-57 |
JJ |
denotes |
fundamental |
T295 |
58-60 |
IN |
denotes |
to |
T296 |
61-67 |
NN |
denotes |
animal |
T297 |
68-79 |
NN |
denotes |
development |
T298 |
79-81 |
, |
denotes |
, |
T299 |
81-87 |
JJ |
denotes |
immune |
T300 |
88-96 |
NN |
denotes |
function |
T301 |
97-100 |
CC |
denotes |
and |
T302 |
101-109 |
JJ |
denotes |
cellular |
T303 |
110-121 |
NN |
denotes |
homeostasis |
T304 |
121-122 |
. |
denotes |
. |
T305 |
122-285 |
sentence |
denotes |
The phosphatidylserine receptor (Ptdsr) on phagocytes has been implicated in the recognition and engulfment of apoptotic cells and in anti-inflammatory signaling. |
T306 |
123-126 |
DT |
denotes |
The |
T307 |
146-154 |
NN |
denotes |
receptor |
T308 |
127-145 |
NN |
denotes |
phosphatidylserine |
T309 |
186-196 |
VBN |
denotes |
implicated |
T310 |
155-156 |
-LRB- |
denotes |
( |
T311 |
156-161 |
NN |
denotes |
Ptdsr |
T312 |
161-162 |
-RRB- |
denotes |
) |
T313 |
163-165 |
IN |
denotes |
on |
T314 |
166-176 |
NNS |
denotes |
phagocytes |
T315 |
177-180 |
VBZ |
denotes |
has |
T316 |
181-185 |
VBN |
denotes |
been |
T317 |
197-199 |
IN |
denotes |
in |
T318 |
200-203 |
DT |
denotes |
the |
T319 |
204-215 |
NN |
denotes |
recognition |
T320 |
216-219 |
CC |
denotes |
and |
T321 |
220-230 |
NN |
denotes |
engulfment |
T322 |
231-233 |
IN |
denotes |
of |
T323 |
234-243 |
JJ |
denotes |
apoptotic |
T324 |
244-249 |
NNS |
denotes |
cells |
T325 |
250-253 |
CC |
denotes |
and |
T326 |
254-256 |
IN |
denotes |
in |
T327 |
257-274 |
JJ |
denotes |
anti-inflammatory |
T328 |
275-284 |
NN |
denotes |
signaling |
T329 |
284-285 |
. |
denotes |
. |
T330 |
285-410 |
sentence |
denotes |
To determine the biological function of the phosphatidylserine receptor in vivo, we inactivated the Ptdsr gene in the mouse. |
T331 |
286-288 |
TO |
denotes |
To |
T332 |
289-298 |
VB |
denotes |
determine |
T333 |
370-381 |
VBD |
denotes |
inactivated |
T334 |
299-302 |
DT |
denotes |
the |
T335 |
314-322 |
NN |
denotes |
function |
T336 |
303-313 |
JJ |
denotes |
biological |
T337 |
323-325 |
IN |
denotes |
of |
T338 |
326-329 |
DT |
denotes |
the |
T339 |
349-357 |
NN |
denotes |
receptor |
T341 |
358-360 |
FW |
denotes |
in |
T342 |
361-365 |
FW |
denotes |
vivo |
T343 |
365-367 |
, |
denotes |
, |
T344 |
367-369 |
PRP |
denotes |
we |
T345 |
382-385 |
DT |
denotes |
the |
T346 |
392-396 |
NN |
denotes |
gene |
T347 |
386-391 |
NN |
denotes |
Ptdsr |
T348 |
397-399 |
IN |
denotes |
in |
T349 |
400-403 |
DT |
denotes |
the |
T350 |
404-409 |
NN |
denotes |
mouse |
T351 |
409-410 |
. |
denotes |
. |
T352 |
410-419 |
sentence |
denotes |
Results |
T353 |
412-419 |
NNS |
denotes |
Results |
T354 |
419-605 |
sentence |
denotes |
Ablation of Ptdsr function in mice causes perinatal lethality, growth retardation and a delay in terminal differentiation of the kidney, intestine, liver and lungs during embryogenesis. |
T355 |
420-428 |
NN |
denotes |
Ablation |
T356 |
455-461 |
VBZ |
denotes |
causes |
T357 |
429-431 |
IN |
denotes |
of |
T358 |
432-437 |
NN |
denotes |
Ptdsr |
T359 |
438-446 |
NN |
denotes |
function |
T360 |
447-449 |
IN |
denotes |
in |
T361 |
450-454 |
NNS |
denotes |
mice |
T362 |
462-471 |
JJ |
denotes |
perinatal |
T363 |
472-481 |
NN |
denotes |
lethality |
T364 |
481-483 |
, |
denotes |
, |
T365 |
483-489 |
NN |
denotes |
growth |
T366 |
490-501 |
NN |
denotes |
retardation |
T367 |
502-505 |
CC |
denotes |
and |
T368 |
506-507 |
DT |
denotes |
a |
T369 |
508-513 |
NN |
denotes |
delay |
T370 |
514-516 |
IN |
denotes |
in |
T371 |
517-525 |
JJ |
denotes |
terminal |
T372 |
526-541 |
NN |
denotes |
differentiation |
T373 |
542-544 |
IN |
denotes |
of |
T374 |
545-548 |
DT |
denotes |
the |
T375 |
549-555 |
NN |
denotes |
kidney |
T376 |
555-557 |
, |
denotes |
, |
T377 |
557-566 |
NN |
denotes |
intestine |
T378 |
566-568 |
, |
denotes |
, |
T379 |
568-573 |
NN |
denotes |
liver |
T380 |
574-577 |
CC |
denotes |
and |
T381 |
578-583 |
NNS |
denotes |
lungs |
T382 |
584-590 |
IN |
denotes |
during |
T383 |
591-604 |
NN |
denotes |
embryogenesis |
T384 |
604-605 |
. |
denotes |
. |
T385 |
605-759 |
sentence |
denotes |
Moreover, eye development can be severely disturbed, ranging from defects in retinal differentiation to complete unilateral or bilateral absence of eyes. |
T386 |
606-614 |
RB |
denotes |
Moreover |
T387 |
648-657 |
VBN |
denotes |
disturbed |
T388 |
614-616 |
, |
denotes |
, |
T389 |
616-619 |
NN |
denotes |
eye |
T390 |
620-631 |
NN |
denotes |
development |
T391 |
632-635 |
MD |
denotes |
can |
T392 |
636-638 |
VB |
denotes |
be |
T393 |
639-647 |
RB |
denotes |
severely |
T394 |
657-659 |
, |
denotes |
, |
T395 |
659-666 |
VBG |
denotes |
ranging |
T396 |
667-671 |
IN |
denotes |
from |
T397 |
672-679 |
NNS |
denotes |
defects |
T398 |
680-682 |
IN |
denotes |
in |
T399 |
683-690 |
JJ |
denotes |
retinal |
T400 |
691-706 |
NN |
denotes |
differentiation |
T401 |
707-709 |
IN |
denotes |
to |
T402 |
710-718 |
JJ |
denotes |
complete |
T403 |
743-750 |
NN |
denotes |
absence |
T404 |
719-729 |
JJ |
denotes |
unilateral |
T405 |
730-732 |
CC |
denotes |
or |
T406 |
733-742 |
JJ |
denotes |
bilateral |
T407 |
751-753 |
IN |
denotes |
of |
T408 |
754-758 |
NNS |
denotes |
eyes |
T409 |
758-759 |
. |
denotes |
. |
T410 |
759-889 |
sentence |
denotes |
Ptdsr -/- mice with anophthalmia develop novel lesions, with induction of ectopic retinal-pigmented epithelium in nasal cavities. |
T411 |
760-765 |
NN |
denotes |
Ptdsr |
T412 |
770-774 |
NNS |
denotes |
mice |
T413 |
766-767 |
SYM |
denotes |
- |
T414 |
767-768 |
HYPH |
denotes |
/ |
T415 |
768-769 |
SYM |
denotes |
- |
T416 |
793-800 |
VBP |
denotes |
develop |
T417 |
775-779 |
IN |
denotes |
with |
T418 |
780-792 |
NN |
denotes |
anophthalmia |
T419 |
801-806 |
JJ |
denotes |
novel |
T420 |
807-814 |
NNS |
denotes |
lesions |
T421 |
814-816 |
, |
denotes |
, |
T422 |
816-820 |
IN |
denotes |
with |
T423 |
821-830 |
NN |
denotes |
induction |
T424 |
831-833 |
IN |
denotes |
of |
T425 |
834-841 |
JJ |
denotes |
ectopic |
T426 |
860-870 |
NN |
denotes |
epithelium |
T427 |
842-849 |
RB |
denotes |
retinal |
T428 |
850-859 |
VBN |
denotes |
pigmented |
T429 |
849-850 |
HYPH |
denotes |
- |
T430 |
871-873 |
IN |
denotes |
in |
T431 |
874-879 |
JJ |
denotes |
nasal |
T432 |
880-888 |
NNS |
denotes |
cavities |
T433 |
888-889 |
. |
denotes |
. |
T434 |
889-1213 |
sentence |
denotes |
A comprehensive investigation of apoptotic cell clearance in vivo and in vitro demonstrated that engulfment of apoptotic cells was normal in Ptdsr knockout mice, but Ptdsr-deficient macrophages were impaired in pro- and anti-inflammatory cytokine signaling after stimulation with apoptotic cells or with lipopolysaccharide. |
T435 |
890-891 |
DT |
denotes |
A |
T436 |
906-919 |
NN |
denotes |
investigation |
T437 |
892-905 |
JJ |
denotes |
comprehensive |
T438 |
969-981 |
VBD |
denotes |
demonstrated |
T439 |
920-922 |
IN |
denotes |
of |
T440 |
923-932 |
JJ |
denotes |
apoptotic |
T441 |
938-947 |
NN |
denotes |
clearance |
T442 |
933-937 |
NN |
denotes |
cell |
T443 |
948-950 |
FW |
denotes |
in |
T444 |
951-955 |
FW |
denotes |
vivo |
T445 |
956-959 |
CC |
denotes |
and |
T446 |
960-962 |
FW |
denotes |
in |
T447 |
963-968 |
FW |
denotes |
vitro |
T448 |
982-986 |
IN |
denotes |
that |
T449 |
1017-1020 |
VBD |
denotes |
was |
T450 |
987-997 |
NN |
denotes |
engulfment |
T451 |
998-1000 |
IN |
denotes |
of |
T452 |
1001-1010 |
JJ |
denotes |
apoptotic |
T453 |
1011-1016 |
NNS |
denotes |
cells |
T454 |
1021-1027 |
JJ |
denotes |
normal |
T455 |
1028-1030 |
IN |
denotes |
in |
T456 |
1031-1036 |
NN |
denotes |
Ptdsr |
T457 |
1046-1050 |
NNS |
denotes |
mice |
T458 |
1037-1045 |
NN |
denotes |
knockout |
T459 |
1050-1052 |
, |
denotes |
, |
T460 |
1052-1055 |
CC |
denotes |
but |
T461 |
1056-1061 |
NN |
denotes |
Ptdsr |
T462 |
1062-1071 |
JJ |
denotes |
deficient |
T463 |
1061-1062 |
HYPH |
denotes |
- |
T464 |
1072-1083 |
NNS |
denotes |
macrophages |
T465 |
1089-1097 |
VBN |
denotes |
impaired |
T466 |
1084-1088 |
VBD |
denotes |
were |
T467 |
1098-1100 |
IN |
denotes |
in |
T468 |
1101-1104 |
AFX |
denotes |
pro |
T469 |
1110-1127 |
JJ |
denotes |
anti-inflammatory |
T470 |
1104-1105 |
HYPH |
denotes |
- |
T471 |
1106-1109 |
CC |
denotes |
and |
T472 |
1137-1146 |
NN |
denotes |
signaling |
T473 |
1128-1136 |
NN |
denotes |
cytokine |
T474 |
1147-1152 |
IN |
denotes |
after |
T475 |
1153-1164 |
NN |
denotes |
stimulation |
T476 |
1165-1169 |
IN |
denotes |
with |
T477 |
1170-1179 |
JJ |
denotes |
apoptotic |
T478 |
1180-1185 |
NNS |
denotes |
cells |
T479 |
1186-1188 |
CC |
denotes |
or |
T480 |
1189-1193 |
IN |
denotes |
with |
T481 |
1194-1212 |
NN |
denotes |
lipopolysaccharide |
T482 |
1212-1213 |
. |
denotes |
. |
T483 |
1213-1225 |
sentence |
denotes |
Conclusion |
T484 |
1215-1225 |
NN |
denotes |
Conclusion |
T485 |
1225-1360 |
sentence |
denotes |
Ptdsr is essential for the development and differentiation of multiple organs during embryogenesis but not for apoptotic cell removal. |
T486 |
1226-1231 |
NN |
denotes |
Ptdsr |
T487 |
1232-1234 |
VBZ |
denotes |
is |
T488 |
1235-1244 |
JJ |
denotes |
essential |
T489 |
1245-1248 |
IN |
denotes |
for |
T490 |
1249-1252 |
DT |
denotes |
the |
T491 |
1253-1264 |
NN |
denotes |
development |
T492 |
1265-1268 |
CC |
denotes |
and |
T493 |
1269-1284 |
NN |
denotes |
differentiation |
T494 |
1285-1287 |
IN |
denotes |
of |
T495 |
1288-1296 |
JJ |
denotes |
multiple |
T496 |
1297-1303 |
NNS |
denotes |
organs |
T497 |
1304-1310 |
IN |
denotes |
during |
T498 |
1311-1324 |
NN |
denotes |
embryogenesis |
T499 |
1325-1328 |
CC |
denotes |
but |
T500 |
1329-1332 |
RB |
denotes |
not |
T501 |
1333-1336 |
IN |
denotes |
for |
T502 |
1337-1346 |
JJ |
denotes |
apoptotic |
T503 |
1347-1351 |
NN |
denotes |
cell |
T504 |
1352-1359 |
NN |
denotes |
removal |
T505 |
1359-1360 |
. |
denotes |
. |
T506 |
1360-1471 |
sentence |
denotes |
Ptdsr may thus have a novel, unexpected developmental function as an important differentiation-promoting gene. |
T507 |
1361-1366 |
NN |
denotes |
Ptdsr |
T508 |
1376-1380 |
VB |
denotes |
have |
T509 |
1367-1370 |
MD |
denotes |
may |
T510 |
1371-1375 |
RB |
denotes |
thus |
T511 |
1381-1382 |
DT |
denotes |
a |
T512 |
1415-1423 |
NN |
denotes |
function |
T513 |
1383-1388 |
JJ |
denotes |
novel |
T514 |
1388-1390 |
, |
denotes |
, |
T515 |
1390-1400 |
JJ |
denotes |
unexpected |
T516 |
1401-1414 |
JJ |
denotes |
developmental |
T517 |
1424-1426 |
IN |
denotes |
as |
T518 |
1427-1429 |
DT |
denotes |
an |
T519 |
1466-1470 |
NN |
denotes |
gene |
T520 |
1430-1439 |
JJ |
denotes |
important |
T521 |
1440-1455 |
NN |
denotes |
differentiation |
T522 |
1456-1465 |
VBG |
denotes |
promoting |
T523 |
1455-1456 |
HYPH |
denotes |
- |
T524 |
1470-1471 |
. |
denotes |
. |
T525 |
1471-1626 |
sentence |
denotes |
Moreover, Ptdsr is not required for apoptotic cell clearance by macrophages but seems to be necessary for the regulation of macrophage cytokine responses. |
T526 |
1472-1480 |
RB |
denotes |
Moreover |
T527 |
1495-1503 |
VBN |
denotes |
required |
T528 |
1480-1482 |
, |
denotes |
, |
T529 |
1482-1487 |
NN |
denotes |
Ptdsr |
T530 |
1488-1490 |
VBZ |
denotes |
is |
T531 |
1491-1494 |
RB |
denotes |
not |
T532 |
1504-1507 |
IN |
denotes |
for |
T533 |
1508-1517 |
JJ |
denotes |
apoptotic |
T534 |
1518-1522 |
NN |
denotes |
cell |
T535 |
1523-1532 |
NN |
denotes |
clearance |
T536 |
1533-1535 |
IN |
denotes |
by |
T537 |
1536-1547 |
NNS |
denotes |
macrophages |
T538 |
1548-1551 |
CC |
denotes |
but |
T539 |
1552-1557 |
VBZ |
denotes |
seems |
T540 |
1558-1560 |
TO |
denotes |
to |
T541 |
1561-1563 |
VB |
denotes |
be |
T542 |
1564-1573 |
JJ |
denotes |
necessary |
T543 |
1574-1577 |
IN |
denotes |
for |
T544 |
1578-1581 |
DT |
denotes |
the |
T545 |
1582-1592 |
NN |
denotes |
regulation |
T546 |
1593-1595 |
IN |
denotes |
of |
T547 |
1596-1606 |
NN |
denotes |
macrophage |
T548 |
1607-1615 |
NN |
denotes |
cytokine |
T549 |
1616-1625 |
NNS |
denotes |
responses |
T550 |
1625-1626 |
. |
denotes |
. |
T551 |
1626-1762 |
sentence |
denotes |
These results clearly contradict the current view that the phosphatidylserine receptor primarily functions in apoptotic cell clearance. |
T552 |
1627-1632 |
DT |
denotes |
These |
T553 |
1633-1640 |
NNS |
denotes |
results |
T554 |
1649-1659 |
VBP |
denotes |
contradict |
T555 |
1641-1648 |
RB |
denotes |
clearly |
T556 |
1660-1663 |
DT |
denotes |
the |
T557 |
1672-1676 |
NN |
denotes |
view |
T558 |
1664-1671 |
JJ |
denotes |
current |
T559 |
1677-1681 |
IN |
denotes |
that |
T560 |
1724-1733 |
VBZ |
denotes |
functions |
T561 |
1682-1685 |
DT |
denotes |
the |
T562 |
1705-1713 |
NN |
denotes |
receptor |
T563 |
1686-1704 |
NN |
denotes |
phosphatidylserine |
T564 |
1714-1723 |
RB |
denotes |
primarily |
T565 |
1734-1736 |
IN |
denotes |
in |
T566 |
1737-1746 |
JJ |
denotes |
apoptotic |
T567 |
1747-1751 |
NN |
denotes |
cell |
T568 |
1752-1761 |
NN |
denotes |
clearance |
T569 |
1761-1762 |
. |
denotes |
. |
R44 |
T319 |
T317 |
pobj |
recognition,in |
R45 |
T320 |
T319 |
cc |
and,recognition |
R47 |
T322 |
T319 |
prep |
of,recognition |
R48 |
T323 |
T324 |
amod |
apoptotic,cells |
R49 |
T324 |
T322 |
pobj |
cells,of |
R50 |
T325 |
T317 |
cc |
and,in |
R51 |
T326 |
T317 |
conj |
in,in |
R52 |
T327 |
T328 |
amod |
anti-inflammatory,signaling |
R53 |
T328 |
T326 |
pobj |
signaling,in |
R43 |
T318 |
T319 |
det |
the,recognition |
R17 |
T289 |
T290 |
nsubj |
Phagocytosis,is |
R18 |
T291 |
T289 |
prep |
of,Phagocytosis |
R19 |
T292 |
T293 |
amod |
apoptotic,cells |
R20 |
T293 |
T291 |
pobj |
cells,of |
R21 |
T294 |
T290 |
acomp |
fundamental,is |
R22 |
T295 |
T294 |
prep |
to,fundamental |
R23 |
T296 |
T297 |
compound |
animal,development |
R24 |
T297 |
T295 |
pobj |
development,to |
R25 |
T298 |
T297 |
punct |
", ",development |
R26 |
T299 |
T300 |
amod |
immune,function |
R27 |
T300 |
T297 |
conj |
function,development |
R28 |
T301 |
T300 |
cc |
and,function |
R29 |
T302 |
T303 |
amod |
cellular,homeostasis |
R30 |
T303 |
T300 |
conj |
homeostasis,function |
R31 |
T304 |
T290 |
punct |
.,is |
R32 |
T306 |
T307 |
det |
The,receptor |
R33 |
T307 |
T309 |
nsubjpass |
receptor,implicated |
R34 |
T308 |
T307 |
compound |
phosphatidylserine,receptor |
R35 |
T310 |
T307 |
punct |
(,receptor |
R36 |
T311 |
T307 |
appos |
Ptdsr,receptor |
R37 |
T312 |
T307 |
punct |
),receptor |
R38 |
T313 |
T307 |
prep |
on,receptor |
R39 |
T314 |
T313 |
pobj |
phagocytes,on |
R40 |
T315 |
T309 |
aux |
has,implicated |
R41 |
T316 |
T309 |
auxpass |
been,implicated |
R42 |
T317 |
T309 |
prep |
in,implicated |
R54 |
T329 |
T309 |
punct |
.,implicated |
R55 |
T331 |
T332 |
aux |
To,determine |
R56 |
T332 |
T333 |
advcl |
determine,inactivated |
R57 |
T334 |
T335 |
det |
the,function |
R58 |
T335 |
T332 |
dobj |
function,determine |
R59 |
T336 |
T335 |
amod |
biological,function |
R60 |
T337 |
T335 |
prep |
of,function |
R61 |
T338 |
T339 |
det |
the,receptor |
R62 |
T339 |
T337 |
pobj |
receptor,of |
R63 |
T340 |
T339 |
compound |
phosphatidylserine,receptor |
R64 |
T341 |
T342 |
advmod |
in,vivo |
R65 |
T342 |
T335 |
advmod |
vivo,function |
R66 |
T343 |
T333 |
punct |
", ",inactivated |
R67 |
T344 |
T333 |
nsubj |
we,inactivated |
R68 |
T345 |
T346 |
det |
the,gene |
R69 |
T346 |
T333 |
dobj |
gene,inactivated |
R70 |
T347 |
T346 |
compound |
Ptdsr,gene |
R71 |
T348 |
T333 |
prep |
in,inactivated |
R72 |
T349 |
T350 |
det |
the,mouse |
R73 |
T350 |
T348 |
pobj |
mouse,in |
R74 |
T351 |
T333 |
punct |
.,inactivated |
R75 |
T355 |
T356 |
nsubj |
Ablation,causes |
R76 |
T357 |
T355 |
prep |
of,Ablation |
R77 |
T358 |
T359 |
compound |
Ptdsr,function |
R78 |
T359 |
T357 |
pobj |
function,of |
R79 |
T360 |
T355 |
prep |
in,Ablation |
R80 |
T361 |
T360 |
pobj |
mice,in |
R81 |
T362 |
T363 |
amod |
perinatal,lethality |
R82 |
T363 |
T356 |
dobj |
lethality,causes |
R83 |
T364 |
T363 |
punct |
", ",lethality |
R84 |
T365 |
T366 |
compound |
growth,retardation |
R85 |
T366 |
T363 |
conj |
retardation,lethality |
R86 |
T367 |
T366 |
cc |
and,retardation |
R87 |
T368 |
T369 |
det |
a,delay |
R88 |
T369 |
T366 |
conj |
delay,retardation |
R89 |
T370 |
T369 |
prep |
in,delay |
R90 |
T371 |
T372 |
amod |
terminal,differentiation |
R91 |
T372 |
T370 |
pobj |
differentiation,in |
R92 |
T373 |
T372 |
prep |
of,differentiation |
R93 |
T374 |
T375 |
det |
the,kidney |
R94 |
T375 |
T373 |
pobj |
kidney,of |
R95 |
T376 |
T375 |
punct |
", ",kidney |
R96 |
T377 |
T375 |
conj |
intestine,kidney |
R97 |
T378 |
T377 |
punct |
", ",intestine |
R98 |
T379 |
T377 |
conj |
liver,intestine |
R99 |
T380 |
T379 |
cc |
and,liver |
R100 |
T381 |
T379 |
conj |
lungs,liver |
R101 |
T382 |
T369 |
prep |
during,delay |
R102 |
T383 |
T382 |
pobj |
embryogenesis,during |
R103 |
T384 |
T356 |
punct |
.,causes |
R104 |
T386 |
T387 |
advmod |
Moreover,disturbed |
R105 |
T388 |
T387 |
punct |
", ",disturbed |
R106 |
T389 |
T390 |
compound |
eye,development |
R107 |
T390 |
T387 |
nsubjpass |
development,disturbed |
R108 |
T391 |
T387 |
aux |
can,disturbed |
R109 |
T392 |
T387 |
auxpass |
be,disturbed |
R110 |
T393 |
T387 |
advmod |
severely,disturbed |
R111 |
T394 |
T387 |
punct |
", ",disturbed |
R112 |
T395 |
T387 |
advcl |
ranging,disturbed |
R113 |
T396 |
T395 |
prep |
from,ranging |
R114 |
T397 |
T396 |
pobj |
defects,from |
R115 |
T398 |
T397 |
prep |
in,defects |
R116 |
T399 |
T400 |
amod |
retinal,differentiation |
R117 |
T400 |
T398 |
pobj |
differentiation,in |
R118 |
T401 |
T396 |
prep |
to,from |
R119 |
T402 |
T403 |
amod |
complete,absence |
R121 |
T404 |
T403 |
amod |
unilateral,absence |
R122 |
T405 |
T404 |
cc |
or,unilateral |
R123 |
T406 |
T404 |
conj |
bilateral,unilateral |
R124 |
T407 |
T403 |
prep |
of,absence |
R125 |
T408 |
T407 |
pobj |
eyes,of |
R126 |
T409 |
T387 |
punct |
.,disturbed |
R127 |
T411 |
T412 |
nmod |
Ptdsr,mice |
R129 |
T413 |
T411 |
punct |
-,Ptdsr |
R130 |
T414 |
T411 |
punct |
/,Ptdsr |
R131 |
T415 |
T411 |
punct |
-,Ptdsr |
R132 |
T417 |
T412 |
prep |
with,mice |
R133 |
T418 |
T417 |
pobj |
anophthalmia,with |
R134 |
T419 |
T420 |
amod |
novel,lesions |
R135 |
T420 |
T416 |
dobj |
lesions,develop |
R136 |
T421 |
T420 |
punct |
", ",lesions |
R137 |
T422 |
T420 |
prep |
with,lesions |
R138 |
T423 |
T422 |
pobj |
induction,with |
R139 |
T424 |
T423 |
prep |
of,induction |
R140 |
T425 |
T426 |
amod |
ectopic,epithelium |
R142 |
T427 |
T428 |
advmod |
retinal,pigmented |
R143 |
T428 |
T426 |
amod |
pigmented,epithelium |
R144 |
T429 |
T428 |
punct |
-,pigmented |
R145 |
T430 |
T423 |
prep |
in,induction |
R146 |
T431 |
T432 |
amod |
nasal,cavities |
R147 |
T432 |
T430 |
pobj |
cavities,in |
R148 |
T433 |
T416 |
punct |
.,develop |
R149 |
T435 |
T436 |
det |
A,investigation |
R150 |
T436 |
T438 |
nsubj |
investigation,demonstrated |
R151 |
T437 |
T436 |
amod |
comprehensive,investigation |
R152 |
T439 |
T436 |
prep |
of,investigation |
R153 |
T440 |
T441 |
amod |
apoptotic,clearance |
R154 |
T441 |
T439 |
pobj |
clearance,of |
R155 |
T442 |
T441 |
compound |
cell,clearance |
R156 |
T443 |
T444 |
advmod |
in,vivo |
R157 |
T444 |
T436 |
advmod |
vivo,investigation |
R158 |
T445 |
T444 |
cc |
and,vivo |
R159 |
T446 |
T447 |
advmod |
in,vitro |
R160 |
T447 |
T444 |
conj |
vitro,vivo |
R161 |
T448 |
T449 |
mark |
that,was |
R162 |
T449 |
T438 |
ccomp |
was,demonstrated |
R163 |
T450 |
T449 |
nsubj |
engulfment,was |
R164 |
T451 |
T450 |
prep |
of,engulfment |
R165 |
T452 |
T453 |
amod |
apoptotic,cells |
R166 |
T453 |
T451 |
pobj |
cells,of |
R167 |
T454 |
T449 |
acomp |
normal,was |
R168 |
T455 |
T449 |
prep |
in,was |
R169 |
T456 |
T457 |
compound |
Ptdsr,mice |
R170 |
T457 |
T455 |
pobj |
mice,in |
R171 |
T458 |
T457 |
compound |
knockout,mice |
R172 |
T459 |
T438 |
punct |
", ",demonstrated |
R173 |
T460 |
T438 |
cc |
but,demonstrated |
R174 |
T461 |
T462 |
npadvmod |
Ptdsr,deficient |
R175 |
T462 |
T464 |
amod |
deficient,macrophages |
R176 |
T463 |
T462 |
punct |
-,deficient |
R177 |
T464 |
T465 |
nsubjpass |
macrophages,impaired |
R178 |
T465 |
T438 |
conj |
impaired,demonstrated |
R179 |
T466 |
T465 |
auxpass |
were,impaired |
R180 |
T467 |
T465 |
prep |
in,impaired |
R181 |
T468 |
T469 |
advmod |
pro,anti-inflammatory |
R182 |
T469 |
T472 |
amod |
anti-inflammatory,signaling |
R183 |
T470 |
T469 |
punct |
-,anti-inflammatory |
R184 |
T471 |
T469 |
cc |
and,anti-inflammatory |
R185 |
T472 |
T467 |
pobj |
signaling,in |
R186 |
T473 |
T472 |
compound |
cytokine,signaling |
R187 |
T474 |
T465 |
prep |
after,impaired |
R188 |
T475 |
T474 |
pobj |
stimulation,after |
R189 |
T476 |
T475 |
prep |
with,stimulation |
R190 |
T477 |
T478 |
amod |
apoptotic,cells |
R191 |
T478 |
T476 |
pobj |
cells,with |
R192 |
T479 |
T476 |
cc |
or,with |
R193 |
T480 |
T476 |
conj |
with,with |
R194 |
T481 |
T480 |
pobj |
lipopolysaccharide,with |
R195 |
T482 |
T465 |
punct |
.,impaired |
R196 |
T486 |
T487 |
nsubj |
Ptdsr,is |
R197 |
T488 |
T487 |
acomp |
essential,is |
R198 |
T489 |
T488 |
prep |
for,essential |
R199 |
T490 |
T491 |
det |
the,development |
R200 |
T491 |
T489 |
pobj |
development,for |
R201 |
T492 |
T491 |
cc |
and,development |
R202 |
T493 |
T491 |
conj |
differentiation,development |
R203 |
T494 |
T491 |
prep |
of,development |
R204 |
T495 |
T496 |
amod |
multiple,organs |
R205 |
T496 |
T494 |
pobj |
organs,of |
R206 |
T497 |
T491 |
prep |
during,development |
R207 |
T498 |
T497 |
pobj |
embryogenesis,during |
R208 |
T499 |
T489 |
cc |
but,for |
R209 |
T500 |
T499 |
neg |
not,but |
R210 |
T501 |
T489 |
conj |
for,for |
R211 |
T502 |
T503 |
amod |
apoptotic,cell |
R212 |
T503 |
T504 |
compound |
cell,removal |
R213 |
T504 |
T501 |
pobj |
removal,for |
R214 |
T505 |
T487 |
punct |
.,is |
R215 |
T507 |
T508 |
nsubj |
Ptdsr,have |
R216 |
T509 |
T508 |
aux |
may,have |
R217 |
T510 |
T508 |
advmod |
thus,have |
R218 |
T511 |
T512 |
det |
a,function |
R219 |
T512 |
T508 |
dobj |
function,have |
R220 |
T513 |
T512 |
amod |
novel,function |
R221 |
T514 |
T512 |
punct |
", ",function |
R222 |
T515 |
T512 |
amod |
unexpected,function |
R223 |
T516 |
T512 |
amod |
developmental,function |
R224 |
T517 |
T512 |
prep |
as,function |
R225 |
T518 |
T519 |
det |
an,gene |
R226 |
T519 |
T517 |
pobj |
gene,as |
R227 |
T520 |
T519 |
amod |
important,gene |
R228 |
T521 |
T522 |
npadvmod |
differentiation,promoting |
R229 |
T522 |
T519 |
amod |
promoting,gene |
R230 |
T523 |
T522 |
punct |
-,promoting |
R231 |
T524 |
T508 |
punct |
.,have |
R232 |
T526 |
T527 |
advmod |
Moreover,required |
R233 |
T528 |
T527 |
punct |
", ",required |
R234 |
T529 |
T527 |
nsubjpass |
Ptdsr,required |
R235 |
T530 |
T527 |
auxpass |
is,required |
R236 |
T531 |
T527 |
neg |
not,required |
R237 |
T532 |
T527 |
prep |
for,required |
R238 |
T533 |
T534 |
amod |
apoptotic,cell |
R239 |
T534 |
T535 |
compound |
cell,clearance |
R240 |
T535 |
T532 |
pobj |
clearance,for |
R241 |
T536 |
T535 |
prep |
by,clearance |
R242 |
T537 |
T536 |
pobj |
macrophages,by |
R243 |
T538 |
T527 |
cc |
but,required |
R244 |
T539 |
T527 |
conj |
seems,required |
R245 |
T540 |
T541 |
aux |
to,be |
R246 |
T541 |
T539 |
xcomp |
be,seems |
R247 |
T542 |
T541 |
acomp |
necessary,be |
R248 |
T543 |
T542 |
prep |
for,necessary |
R249 |
T544 |
T545 |
det |
the,regulation |
R250 |
T545 |
T543 |
pobj |
regulation,for |
R251 |
T546 |
T545 |
prep |
of,regulation |
R252 |
T547 |
T548 |
compound |
macrophage,cytokine |
R253 |
T548 |
T549 |
compound |
cytokine,responses |
R254 |
T549 |
T546 |
pobj |
responses,of |
R255 |
T550 |
T527 |
punct |
.,required |
R256 |
T552 |
T553 |
det |
These,results |
R257 |
T553 |
T554 |
nsubj |
results,contradict |
R258 |
T555 |
T554 |
advmod |
clearly,contradict |
R259 |
T556 |
T557 |
det |
the,view |
R260 |
T557 |
T554 |
dobj |
view,contradict |
R261 |
T558 |
T557 |
amod |
current,view |
R262 |
T559 |
T560 |
mark |
that,functions |
R263 |
T560 |
T557 |
acl |
functions,view |
R264 |
T561 |
T562 |
det |
the,receptor |
R265 |
T562 |
T560 |
nsubj |
receptor,functions |
R266 |
T563 |
T562 |
compound |
phosphatidylserine,receptor |
R267 |
T564 |
T560 |
advmod |
primarily,functions |
R268 |
T565 |
T560 |
prep |
in,functions |
R269 |
T566 |
T567 |
amod |
apoptotic,cell |
R270 |
T567 |
T568 |
compound |
cell,clearance |
R271 |
T568 |
T565 |
pobj |
clearance,in |
R272 |
T569 |
T554 |
punct |
.,contradict |
R120 |
T403 |
T401 |
pobj |
absence,to |
R46 |
T321 |
T319 |
conj |
engulfment,recognition |
R128 |
T412 |
T416 |
nsubj |
mice,develop |
R141 |
T426 |
T424 |
pobj |
epithelium,of |