PMC:548520 / 8940-10098 JSONTXT

Annnotations TAB JSON ListView MergeView

    craft-ca-core-ex-dev

    {"project":"craft-ca-core-ex-dev","denotations":[{"id":"T8520","span":{"begin":13,"end":21},"obj":"CHEBI:10545"},{"id":"T8521","span":{"begin":36,"end":39},"obj":"PR_EXT:000005904"},{"id":"T8522","span":{"begin":39,"end":40},"obj":"SO_EXT:sequence_nullness_or_absence"},{"id":"T8523","span":{"begin":41,"end":42},"obj":"SO_EXT:sequence_nullness_or_absence"},{"id":"T8524","span":{"begin":43,"end":49},"obj":"UBERON:0000966"},{"id":"T8525","span":{"begin":81,"end":89},"obj":"CHEBI:10545"},{"id":"T8526","span":{"begin":104,"end":107},"obj":"PR_EXT:000005904"},{"id":"T8527","span":{"begin":107,"end":108},"obj":"SO_EXT:sequence_nullness_or_absence"},{"id":"T8528","span":{"begin":109,"end":110},"obj":"SO_EXT:sequence_nullness_or_absence"},{"id":"T8529","span":{"begin":125,"end":138},"obj":"GO:0001750"},{"id":"T8530","span":{"begin":125,"end":144},"obj":"UBERON:0003926"},{"id":"T8531","span":{"begin":162,"end":174},"obj":"GO:0042384"},{"id":"T8532","span":{"begin":182,"end":195},"obj":"CL:0000210"},{"id":"T8533","span":{"begin":182,"end":204},"obj":"_FRAGMENT"},{"id":"T8534","span":{"begin":212,"end":218},"obj":"UBERON:0001787"},{"id":"T8535","span":{"begin":205,"end":208},"obj":"PR_EXT:000005904"},{"id":"T8536","span":{"begin":208,"end":209},"obj":"SO_EXT:sequence_nullness_or_absence"},{"id":"T8537","span":{"begin":210,"end":211},"obj":"SO_EXT:sequence_nullness_or_absence"},{"id":"T8538","span":{"begin":220,"end":246},"obj":"GO:0032391"},{"id":"T8539","span":{"begin":317,"end":334},"obj":"GO:0032391"},{"id":"T8540","span":{"begin":370,"end":380},"obj":"GO:0005874"},{"id":"T8541","span":{"begin":397,"end":403},"obj":"GO:0005929"},{"id":"T8542","span":{"begin":410,"end":416},"obj":"GO:0005929"},{"id":"T8543","span":{"begin":453,"end":457},"obj":"CL_GO_EXT:cell"},{"id":"T8544","span":{"begin":453,"end":465},"obj":"GO:0005634"},{"id":"T8545","span":{"begin":467,"end":468},"obj":"GO:0005634"},{"id":"T8546","span":{"begin":480,"end":488},"obj":"GO:0030263"},{"id":"T8547","span":{"begin":516,"end":522},"obj":"GO:0031012"},{"id":"T8548","span":{"begin":524,"end":526},"obj":"GO:0031012"},{"id":"T8549","span":{"begin":596,"end":615},"obj":"GO:0031988"},{"id":"T8550","span":{"begin":641,"end":654},"obj":"CL:0000210"},{"id":"T8551","span":{"begin":680,"end":688},"obj":"GO_EXT:biological_release"},{"id":"T8552","span":{"begin":694,"end":708},"obj":"GO:0001917"},{"id":"T8553","span":{"begin":734,"end":761},"obj":"GO:0032391"},{"id":"T8554","span":{"begin":787,"end":790},"obj":"PR_EXT:000005904"},{"id":"T8555","span":{"begin":790,"end":791},"obj":"SO_EXT:sequence_nullness_or_absence"},{"id":"T8556","span":{"begin":792,"end":793},"obj":"SO_EXT:sequence_nullness_or_absence"},{"id":"T8557","span":{"begin":794,"end":807},"obj":"CL:0000210"},{"id":"T8558","span":{"begin":858,"end":869},"obj":"GO:0005874"},{"id":"T8559","span":{"begin":912,"end":920},"obj":"CHEBI:10545"},{"id":"T8560","span":{"begin":941,"end":960},"obj":"GO:0031988"},{"id":"T8561","span":{"begin":997,"end":1011},"obj":"GO:0001917"},{"id":"T8562","span":{"begin":1015,"end":1018},"obj":"PR_EXT:000005904"},{"id":"T8563","span":{"begin":1018,"end":1019},"obj":"SO_EXT:sequence_nullness_or_absence"},{"id":"T8564","span":{"begin":1020,"end":1021},"obj":"SO_EXT:sequence_nullness_or_absence"},{"id":"T8565","span":{"begin":1022,"end":1036},"obj":"CL:0000210"},{"id":"T8566","span":{"begin":1058,"end":1072},"obj":"GO:0001917"},{"id":"T8567","span":{"begin":1089,"end":1096},"obj":"UBERON:0001773"},{"id":"T8568","span":{"begin":1111,"end":1120},"obj":"CHEBI_EXT:26130"},{"id":"T8569","span":{"begin":1121,"end":1131},"obj":"UBERON:0000483"}],"relations":[{"id":"R5180","pred":"_lexicallyChainedTo","subj":"T8534","obj":"T8533"}],"text":"Transmission electron micrograph of Crx-/- retina at P21 (A and B), and scanning electron micrograph of Crx-/- at P10 (C) of outer segment layer. (A) Evidence of ciliogenesis in the photoreceptor layer of Crx-/- retina. Nonmotile connecting cilia were observed in cross section (arrowheads 1,2, and 3, for examples). Connecting cilium 1 (arrowhead 1) demonstrated seven microtuble doublets, while cilium 2 and cilium 3 exhibited nine. In A, a displaced cell nucleus (n) appearing pyknotic and abnormal deposition of matrix (mx) material of unknown identity were seen, along with large amounts of membranous vesicles (arrow) which filled the photoreceptor space and appeared to be released from inner segments. Scale bar = 3.7 μm. (B) Nonmotile connecting cilium in cross section, from a Crx-/- photoreceptor, demonstrating characteristic 9+0 radial array of microtubule doublets. Scale bar = 88 nm. (C) Scanning electron micrograph (SEM) of membranous vesicles (arrow shows one example) shed from inner segments of Crx-/- photoreceptors at P10. Figure shows inner segments viewed from the scleral side with the pigmented epithelium removed. Scale bar = 1 μm."}

    craft-ca-core-dev

    {"project":"craft-ca-core-dev","denotations":[{"id":"T8482","span":{"begin":13,"end":21},"obj":"CHEBI:10545"},{"id":"T8483","span":{"begin":36,"end":39},"obj":"PR:000005904"},{"id":"T8484","span":{"begin":43,"end":49},"obj":"UBERON:0000966"},{"id":"T8485","span":{"begin":81,"end":89},"obj":"CHEBI:10545"},{"id":"T8486","span":{"begin":104,"end":107},"obj":"PR:000005904"},{"id":"T8487","span":{"begin":125,"end":138},"obj":"GO:0001750"},{"id":"T8488","span":{"begin":125,"end":144},"obj":"UBERON:0003926"},{"id":"T8489","span":{"begin":162,"end":174},"obj":"GO:0042384"},{"id":"T8490","span":{"begin":182,"end":195},"obj":"CL:0000210"},{"id":"T8491","span":{"begin":182,"end":204},"obj":"_FRAGMENT"},{"id":"T8492","span":{"begin":212,"end":218},"obj":"UBERON:0001787"},{"id":"T8493","span":{"begin":205,"end":208},"obj":"PR:000005904"},{"id":"T8494","span":{"begin":220,"end":246},"obj":"GO:0032391"},{"id":"T8495","span":{"begin":317,"end":334},"obj":"GO:0032391"},{"id":"T8496","span":{"begin":370,"end":380},"obj":"GO:0005874"},{"id":"T8497","span":{"begin":397,"end":403},"obj":"GO:0005929"},{"id":"T8498","span":{"begin":410,"end":416},"obj":"GO:0005929"},{"id":"T8499","span":{"begin":453,"end":465},"obj":"GO:0005634"},{"id":"T8500","span":{"begin":467,"end":468},"obj":"GO:0005634"},{"id":"T8501","span":{"begin":480,"end":488},"obj":"GO:0030263"},{"id":"T8502","span":{"begin":516,"end":522},"obj":"GO:0031012"},{"id":"T8503","span":{"begin":524,"end":526},"obj":"GO:0031012"},{"id":"T8504","span":{"begin":596,"end":615},"obj":"GO:0031988"},{"id":"T8505","span":{"begin":641,"end":654},"obj":"CL:0000210"},{"id":"T8506","span":{"begin":694,"end":708},"obj":"GO:0001917"},{"id":"T8507","span":{"begin":734,"end":761},"obj":"GO:0032391"},{"id":"T8508","span":{"begin":787,"end":790},"obj":"PR:000005904"},{"id":"T8509","span":{"begin":794,"end":807},"obj":"CL:0000210"},{"id":"T8510","span":{"begin":858,"end":869},"obj":"GO:0005874"},{"id":"T8511","span":{"begin":912,"end":920},"obj":"CHEBI:10545"},{"id":"T8512","span":{"begin":941,"end":960},"obj":"GO:0031988"},{"id":"T8513","span":{"begin":997,"end":1011},"obj":"GO:0001917"},{"id":"T8514","span":{"begin":1015,"end":1018},"obj":"PR:000005904"},{"id":"T8515","span":{"begin":1022,"end":1036},"obj":"CL:0000210"},{"id":"T8516","span":{"begin":1058,"end":1072},"obj":"GO:0001917"},{"id":"T8517","span":{"begin":1089,"end":1096},"obj":"UBERON:0001773"},{"id":"T8518","span":{"begin":1111,"end":1120},"obj":"CHEBI:26130"},{"id":"T8519","span":{"begin":1121,"end":1131},"obj":"UBERON:0000483"}],"relations":[{"id":"R5179","pred":"_lexicallyChainedTo","subj":"T8492","obj":"T8491"}],"text":"Transmission electron micrograph of Crx-/- retina at P21 (A and B), and scanning electron micrograph of Crx-/- at P10 (C) of outer segment layer. (A) Evidence of ciliogenesis in the photoreceptor layer of Crx-/- retina. Nonmotile connecting cilia were observed in cross section (arrowheads 1,2, and 3, for examples). Connecting cilium 1 (arrowhead 1) demonstrated seven microtuble doublets, while cilium 2 and cilium 3 exhibited nine. In A, a displaced cell nucleus (n) appearing pyknotic and abnormal deposition of matrix (mx) material of unknown identity were seen, along with large amounts of membranous vesicles (arrow) which filled the photoreceptor space and appeared to be released from inner segments. Scale bar = 3.7 μm. (B) Nonmotile connecting cilium in cross section, from a Crx-/- photoreceptor, demonstrating characteristic 9+0 radial array of microtubule doublets. Scale bar = 88 nm. (C) Scanning electron micrograph (SEM) of membranous vesicles (arrow shows one example) shed from inner segments of Crx-/- photoreceptors at P10. Figure shows inner segments viewed from the scleral side with the pigmented epithelium removed. Scale bar = 1 μm."}

    craft-sa-dev

    {"project":"craft-sa-dev","denotations":[{"id":"T8570","span":{"begin":0,"end":12},"obj":"NN"},{"id":"T8571","span":{"begin":22,"end":32},"obj":"NN"},{"id":"T8572","span":{"begin":13,"end":21},"obj":"NN"},{"id":"T8573","span":{"begin":33,"end":35},"obj":"IN"},{"id":"T8574","span":{"begin":36,"end":39},"obj":"NN"},{"id":"T8575","span":{"begin":43,"end":49},"obj":"NN"},{"id":"T8576","span":{"begin":39,"end":40},"obj":"SYM"},{"id":"T8577","span":{"begin":40,"end":41},"obj":"HYPH"},{"id":"T8578","span":{"begin":41,"end":42},"obj":"SYM"},{"id":"T8579","span":{"begin":50,"end":52},"obj":"IN"},{"id":"T8580","span":{"begin":53,"end":56},"obj":"NN"},{"id":"T8581","span":{"begin":57,"end":58},"obj":"-LRB-"},{"id":"T8582","span":{"begin":58,"end":59},"obj":"NN"},{"id":"T8583","span":{"begin":60,"end":63},"obj":"CC"},{"id":"T8584","span":{"begin":64,"end":65},"obj":"NN"},{"id":"T8585","span":{"begin":65,"end":66},"obj":"-RRB-"},{"id":"T8586","span":{"begin":66,"end":68},"obj":","},{"id":"T8587","span":{"begin":68,"end":71},"obj":"CC"},{"id":"T8588","span":{"begin":72,"end":80},"obj":"VBG"},{"id":"T8589","span":{"begin":90,"end":100},"obj":"NN"},{"id":"T8590","span":{"begin":81,"end":89},"obj":"NN"},{"id":"T8591","span":{"begin":101,"end":103},"obj":"IN"},{"id":"T8592","span":{"begin":104,"end":107},"obj":"NN"},{"id":"T8593","span":{"begin":107,"end":108},"obj":"SYM"},{"id":"T8594","span":{"begin":108,"end":109},"obj":"HYPH"},{"id":"T8595","span":{"begin":109,"end":110},"obj":"SYM"},{"id":"T8596","span":{"begin":111,"end":113},"obj":"IN"},{"id":"T8597","span":{"begin":114,"end":117},"obj":"NN"},{"id":"T8598","span":{"begin":118,"end":119},"obj":"-LRB-"},{"id":"T8599","span":{"begin":119,"end":120},"obj":"NN"},{"id":"T8600","span":{"begin":120,"end":121},"obj":"-RRB-"},{"id":"T8601","span":{"begin":122,"end":124},"obj":"IN"},{"id":"T8602","span":{"begin":125,"end":130},"obj":"JJ"},{"id":"T8603","span":{"begin":131,"end":138},"obj":"NN"},{"id":"T8604","span":{"begin":139,"end":144},"obj":"NN"},{"id":"T8605","span":{"begin":144,"end":145},"obj":"."},{"id":"T8606","span":{"begin":145,"end":219},"obj":"sentence"},{"id":"T8607","span":{"begin":146,"end":147},"obj":"-LRB-"},{"id":"T8608","span":{"begin":147,"end":148},"obj":"LS"},{"id":"T8609","span":{"begin":150,"end":158},"obj":"NN"},{"id":"T8610","span":{"begin":148,"end":149},"obj":"-RRB-"},{"id":"T8611","span":{"begin":159,"end":161},"obj":"IN"},{"id":"T8612","span":{"begin":162,"end":174},"obj":"NN"},{"id":"T8613","span":{"begin":175,"end":177},"obj":"IN"},{"id":"T8614","span":{"begin":178,"end":181},"obj":"DT"},{"id":"T8615","span":{"begin":196,"end":201},"obj":"NN"},{"id":"T8616","span":{"begin":182,"end":195},"obj":"NN"},{"id":"T8617","span":{"begin":202,"end":204},"obj":"IN"},{"id":"T8618","span":{"begin":205,"end":208},"obj":"NN"},{"id":"T8619","span":{"begin":212,"end":218},"obj":"NN"},{"id":"T8620","span":{"begin":208,"end":209},"obj":"SYM"},{"id":"T8621","span":{"begin":209,"end":210},"obj":"HYPH"},{"id":"T8622","span":{"begin":210,"end":211},"obj":"SYM"},{"id":"T8623","span":{"begin":218,"end":219},"obj":"."},{"id":"T8624","span":{"begin":219,"end":316},"obj":"sentence"},{"id":"T8625","span":{"begin":220,"end":229},"obj":"JJ"},{"id":"T8626","span":{"begin":241,"end":246},"obj":"NNS"},{"id":"T8627","span":{"begin":230,"end":240},"obj":"VBG"},{"id":"T8628","span":{"begin":252,"end":260},"obj":"VBN"},{"id":"T8629","span":{"begin":247,"end":251},"obj":"VBD"},{"id":"T8630","span":{"begin":261,"end":263},"obj":"IN"},{"id":"T8631","span":{"begin":264,"end":269},"obj":"NN"},{"id":"T8632","span":{"begin":270,"end":277},"obj":"NN"},{"id":"T8633","span":{"begin":278,"end":279},"obj":"-LRB-"},{"id":"T8634","span":{"begin":290,"end":291},"obj":"CD"},{"id":"T8635","span":{"begin":279,"end":289},"obj":"NNS"},{"id":"T8636","span":{"begin":291,"end":292},"obj":","},{"id":"T8637","span":{"begin":292,"end":293},"obj":"CD"},{"id":"T8638","span":{"begin":293,"end":295},"obj":","},{"id":"T8639","span":{"begin":295,"end":298},"obj":"CC"},{"id":"T8640","span":{"begin":299,"end":300},"obj":"CD"},{"id":"T8641","span":{"begin":300,"end":302},"obj":","},{"id":"T8642","span":{"begin":302,"end":305},"obj":"IN"},{"id":"T8643","span":{"begin":306,"end":314},"obj":"NNS"},{"id":"T8644","span":{"begin":314,"end":315},"obj":"-RRB-"},{"id":"T8645","span":{"begin":315,"end":316},"obj":"."},{"id":"T8646","span":{"begin":316,"end":434},"obj":"sentence"},{"id":"T8647","span":{"begin":317,"end":327},"obj":"VBG"},{"id":"T8648","span":{"begin":328,"end":334},"obj":"NN"},{"id":"T8649","span":{"begin":351,"end":363},"obj":"VBD"},{"id":"T8650","span":{"begin":335,"end":336},"obj":"CD"},{"id":"T8651","span":{"begin":337,"end":338},"obj":"-LRB-"},{"id":"T8652","span":{"begin":338,"end":347},"obj":"NN"},{"id":"T8653","span":{"begin":348,"end":349},"obj":"CD"},{"id":"T8654","span":{"begin":349,"end":350},"obj":"-RRB-"},{"id":"T8655","span":{"begin":364,"end":369},"obj":"CD"},{"id":"T8656","span":{"begin":381,"end":389},"obj":"NNS"},{"id":"T8657","span":{"begin":370,"end":380},"obj":"JJ"},{"id":"T8658","span":{"begin":389,"end":391},"obj":","},{"id":"T8659","span":{"begin":391,"end":396},"obj":"IN"},{"id":"T8660","span":{"begin":419,"end":428},"obj":"VBD"},{"id":"T8661","span":{"begin":397,"end":403},"obj":"NN"},{"id":"T8662","span":{"begin":404,"end":405},"obj":"CD"},{"id":"T8663","span":{"begin":406,"end":409},"obj":"CC"},{"id":"T8664","span":{"begin":410,"end":416},"obj":"NN"},{"id":"T8665","span":{"begin":417,"end":418},"obj":"CD"},{"id":"T8666","span":{"begin":429,"end":433},"obj":"CD"},{"id":"T8667","span":{"begin":433,"end":434},"obj":"."},{"id":"T8668","span":{"begin":434,"end":709},"obj":"sentence"},{"id":"T8669","span":{"begin":435,"end":437},"obj":"IN"},{"id":"T8670","span":{"begin":562,"end":566},"obj":"VBN"},{"id":"T8671","span":{"begin":438,"end":439},"obj":"NN"},{"id":"T8672","span":{"begin":439,"end":441},"obj":","},{"id":"T8673","span":{"begin":441,"end":442},"obj":"DT"},{"id":"T8674","span":{"begin":458,"end":465},"obj":"NN"},{"id":"T8675","span":{"begin":443,"end":452},"obj":"VBN"},{"id":"T8676","span":{"begin":453,"end":457},"obj":"NN"},{"id":"T8677","span":{"begin":466,"end":467},"obj":"-LRB-"},{"id":"T8678","span":{"begin":467,"end":468},"obj":"NN"},{"id":"T8679","span":{"begin":468,"end":469},"obj":"-RRB-"},{"id":"T8680","span":{"begin":470,"end":479},"obj":"VBG"},{"id":"T8681","span":{"begin":480,"end":488},"obj":"JJ"},{"id":"T8682","span":{"begin":489,"end":492},"obj":"CC"},{"id":"T8683","span":{"begin":493,"end":501},"obj":"JJ"},{"id":"T8684","span":{"begin":502,"end":512},"obj":"NN"},{"id":"T8685","span":{"begin":513,"end":515},"obj":"IN"},{"id":"T8686","span":{"begin":516,"end":522},"obj":"NN"},{"id":"T8687","span":{"begin":528,"end":536},"obj":"NN"},{"id":"T8688","span":{"begin":523,"end":524},"obj":"-LRB-"},{"id":"T8689","span":{"begin":524,"end":526},"obj":"NN"},{"id":"T8690","span":{"begin":526,"end":527},"obj":"-RRB-"},{"id":"T8691","span":{"begin":537,"end":539},"obj":"IN"},{"id":"T8692","span":{"begin":540,"end":547},"obj":"JJ"},{"id":"T8693","span":{"begin":548,"end":556},"obj":"NN"},{"id":"T8694","span":{"begin":557,"end":561},"obj":"VBD"},{"id":"T8695","span":{"begin":566,"end":568},"obj":","},{"id":"T8696","span":{"begin":568,"end":573},"obj":"IN"},{"id":"T8697","span":{"begin":574,"end":578},"obj":"IN"},{"id":"T8698","span":{"begin":579,"end":584},"obj":"JJ"},{"id":"T8699","span":{"begin":585,"end":592},"obj":"NNS"},{"id":"T8700","span":{"begin":593,"end":595},"obj":"IN"},{"id":"T8701","span":{"begin":596,"end":606},"obj":"JJ"},{"id":"T8702","span":{"begin":607,"end":615},"obj":"NNS"},{"id":"T8703","span":{"begin":616,"end":617},"obj":"-LRB-"},{"id":"T8704","span":{"begin":617,"end":622},"obj":"NN"},{"id":"T8705","span":{"begin":622,"end":623},"obj":"-RRB-"},{"id":"T8706","span":{"begin":624,"end":629},"obj":"WDT"},{"id":"T8707","span":{"begin":630,"end":636},"obj":"VBD"},{"id":"T8708","span":{"begin":637,"end":640},"obj":"DT"},{"id":"T8709","span":{"begin":655,"end":660},"obj":"NN"},{"id":"T8710","span":{"begin":641,"end":654},"obj":"NN"},{"id":"T8711","span":{"begin":661,"end":664},"obj":"CC"},{"id":"T8712","span":{"begin":665,"end":673},"obj":"VBD"},{"id":"T8713","span":{"begin":674,"end":676},"obj":"TO"},{"id":"T8714","span":{"begin":680,"end":688},"obj":"VBN"},{"id":"T8715","span":{"begin":677,"end":679},"obj":"VB"},{"id":"T8716","span":{"begin":689,"end":693},"obj":"IN"},{"id":"T8717","span":{"begin":694,"end":699},"obj":"JJ"},{"id":"T8718","span":{"begin":700,"end":708},"obj":"NNS"},{"id":"T8719","span":{"begin":708,"end":709},"obj":"."},{"id":"T8720","span":{"begin":709,"end":729},"obj":"sentence"},{"id":"T8721","span":{"begin":710,"end":715},"obj":"NN"},{"id":"T8722","span":{"begin":716,"end":719},"obj":"NN"},{"id":"T8723","span":{"begin":726,"end":728},"obj":"NN"},{"id":"T8724","span":{"begin":720,"end":721},"obj":"SYM"},{"id":"T8725","span":{"begin":722,"end":725},"obj":"CD"},{"id":"T8726","span":{"begin":728,"end":729},"obj":"."},{"id":"T8727","span":{"begin":729,"end":879},"obj":"sentence"},{"id":"T8728","span":{"begin":730,"end":731},"obj":"-LRB-"},{"id":"T8729","span":{"begin":731,"end":732},"obj":"LS"},{"id":"T8730","span":{"begin":755,"end":761},"obj":"NN"},{"id":"T8731","span":{"begin":732,"end":733},"obj":"-RRB-"},{"id":"T8732","span":{"begin":734,"end":743},"obj":"JJ"},{"id":"T8733","span":{"begin":744,"end":754},"obj":"VBG"},{"id":"T8734","span":{"begin":762,"end":764},"obj":"IN"},{"id":"T8735","span":{"begin":765,"end":770},"obj":"NN"},{"id":"T8736","span":{"begin":771,"end":778},"obj":"NN"},{"id":"T8737","span":{"begin":778,"end":780},"obj":","},{"id":"T8738","span":{"begin":780,"end":784},"obj":"IN"},{"id":"T8739","span":{"begin":785,"end":786},"obj":"DT"},{"id":"T8740","span":{"begin":794,"end":807},"obj":"NN"},{"id":"T8741","span":{"begin":787,"end":790},"obj":"NN"},{"id":"T8742","span":{"begin":790,"end":791},"obj":"SYM"},{"id":"T8743","span":{"begin":791,"end":792},"obj":"HYPH"},{"id":"T8744","span":{"begin":792,"end":793},"obj":"SYM"},{"id":"T8745","span":{"begin":807,"end":809},"obj":","},{"id":"T8746","span":{"begin":809,"end":822},"obj":"VBG"},{"id":"T8747","span":{"begin":823,"end":837},"obj":"JJ"},{"id":"T8748","span":{"begin":849,"end":854},"obj":"NN"},{"id":"T8749","span":{"begin":838,"end":839},"obj":"CD"},{"id":"T8750","span":{"begin":840,"end":841},"obj":"CD"},{"id":"T8751","span":{"begin":839,"end":840},"obj":"SYM"},{"id":"T8752","span":{"begin":842,"end":848},"obj":"JJ"},{"id":"T8753","span":{"begin":855,"end":857},"obj":"IN"},{"id":"T8754","span":{"begin":858,"end":869},"obj":"NN"},{"id":"T8755","span":{"begin":870,"end":878},"obj":"NNS"},{"id":"T8756","span":{"begin":878,"end":879},"obj":"."},{"id":"T8757","span":{"begin":879,"end":898},"obj":"sentence"},{"id":"T8758","span":{"begin":880,"end":885},"obj":"NN"},{"id":"T8759","span":{"begin":886,"end":889},"obj":"NN"},{"id":"T8760","span":{"begin":895,"end":897},"obj":"NN"},{"id":"T8761","span":{"begin":890,"end":891},"obj":"SYM"},{"id":"T8762","span":{"begin":892,"end":894},"obj":"CD"},{"id":"T8763","span":{"begin":897,"end":898},"obj":"."},{"id":"T8764","span":{"begin":898,"end":1044},"obj":"sentence"},{"id":"T8765","span":{"begin":899,"end":900},"obj":"-LRB-"},{"id":"T8766","span":{"begin":900,"end":901},"obj":"LS"},{"id":"T8767","span":{"begin":921,"end":931},"obj":"NN"},{"id":"T8768","span":{"begin":901,"end":902},"obj":"-RRB-"},{"id":"T8769","span":{"begin":903,"end":911},"obj":"VBG"},{"id":"T8770","span":{"begin":912,"end":920},"obj":"NN"},{"id":"T8771","span":{"begin":932,"end":933},"obj":"-LRB-"},{"id":"T8772","span":{"begin":933,"end":936},"obj":"NN"},{"id":"T8773","span":{"begin":936,"end":937},"obj":"-RRB-"},{"id":"T8774","span":{"begin":938,"end":940},"obj":"IN"},{"id":"T8775","span":{"begin":941,"end":951},"obj":"JJ"},{"id":"T8776","span":{"begin":952,"end":960},"obj":"NNS"},{"id":"T8777","span":{"begin":961,"end":962},"obj":"-LRB-"},{"id":"T8778","span":{"begin":968,"end":973},"obj":"VBZ"},{"id":"T8779","span":{"begin":962,"end":967},"obj":"NN"},{"id":"T8780","span":{"begin":974,"end":977},"obj":"CD"},{"id":"T8781","span":{"begin":978,"end":985},"obj":"NN"},{"id":"T8782","span":{"begin":985,"end":986},"obj":"-RRB-"},{"id":"T8783","span":{"begin":987,"end":991},"obj":"VBN"},{"id":"T8784","span":{"begin":992,"end":996},"obj":"IN"},{"id":"T8785","span":{"begin":997,"end":1002},"obj":"JJ"},{"id":"T8786","span":{"begin":1003,"end":1011},"obj":"NNS"},{"id":"T8787","span":{"begin":1012,"end":1014},"obj":"IN"},{"id":"T8788","span":{"begin":1015,"end":1018},"obj":"NN"},{"id":"T8789","span":{"begin":1022,"end":1036},"obj":"NNS"},{"id":"T8790","span":{"begin":1018,"end":1019},"obj":"SYM"},{"id":"T8791","span":{"begin":1019,"end":1020},"obj":"HYPH"},{"id":"T8792","span":{"begin":1020,"end":1021},"obj":"SYM"},{"id":"T8793","span":{"begin":1037,"end":1039},"obj":"IN"},{"id":"T8794","span":{"begin":1040,"end":1043},"obj":"NN"},{"id":"T8795","span":{"begin":1043,"end":1044},"obj":"."},{"id":"T8796","span":{"begin":1044,"end":1140},"obj":"sentence"},{"id":"T8797","span":{"begin":1045,"end":1051},"obj":"NN"},{"id":"T8798","span":{"begin":1052,"end":1057},"obj":"VBZ"},{"id":"T8799","span":{"begin":1058,"end":1063},"obj":"JJ"},{"id":"T8800","span":{"begin":1064,"end":1072},"obj":"NNS"},{"id":"T8801","span":{"begin":1073,"end":1079},"obj":"VBN"},{"id":"T8802","span":{"begin":1080,"end":1084},"obj":"IN"},{"id":"T8803","span":{"begin":1085,"end":1088},"obj":"DT"},{"id":"T8804","span":{"begin":1097,"end":1101},"obj":"NN"},{"id":"T8805","span":{"begin":1089,"end":1096},"obj":"JJ"},{"id":"T8806","span":{"begin":1102,"end":1106},"obj":"IN"},{"id":"T8807","span":{"begin":1132,"end":1139},"obj":"VBN"},{"id":"T8808","span":{"begin":1107,"end":1110},"obj":"DT"},{"id":"T8809","span":{"begin":1121,"end":1131},"obj":"NN"},{"id":"T8810","span":{"begin":1111,"end":1120},"obj":"VBN"},{"id":"T8811","span":{"begin":1139,"end":1140},"obj":"."},{"id":"T8812","span":{"begin":1140,"end":1158},"obj":"sentence"},{"id":"T8813","span":{"begin":1141,"end":1146},"obj":"NN"},{"id":"T8814","span":{"begin":1147,"end":1150},"obj":"NN"},{"id":"T8815","span":{"begin":1155,"end":1157},"obj":"NN"},{"id":"T8816","span":{"begin":1151,"end":1152},"obj":"SYM"},{"id":"T8817","span":{"begin":1153,"end":1154},"obj":"CD"},{"id":"T8818","span":{"begin":1157,"end":1158},"obj":"."}],"relations":[{"id":"R5181","pred":"compound","subj":"T8570","obj":"T8571"},{"id":"R5182","pred":"compound","subj":"T8572","obj":"T8571"},{"id":"R5183","pred":"prep","subj":"T8573","obj":"T8571"},{"id":"R5184","pred":"nmod","subj":"T8574","obj":"T8575"},{"id":"R5185","pred":"pobj","subj":"T8575","obj":"T8573"},{"id":"R5186","pred":"punct","subj":"T8576","obj":"T8574"},{"id":"R5187","pred":"punct","subj":"T8577","obj":"T8574"},{"id":"R5188","pred":"punct","subj":"T8578","obj":"T8574"},{"id":"R5189","pred":"prep","subj":"T8579","obj":"T8575"},{"id":"R5190","pred":"pobj","subj":"T8580","obj":"T8579"},{"id":"R5191","pred":"punct","subj":"T8581","obj":"T8582"},{"id":"R5192","pred":"parataxis","subj":"T8582","obj":"T8571"},{"id":"R5193","pred":"cc","subj":"T8583","obj":"T8582"},{"id":"R5194","pred":"conj","subj":"T8584","obj":"T8582"},{"id":"R5195","pred":"punct","subj":"T8585","obj":"T8582"},{"id":"R5196","pred":"punct","subj":"T8586","obj":"T8571"},{"id":"R5197","pred":"cc","subj":"T8587","obj":"T8571"},{"id":"R5198","pred":"amod","subj":"T8588","obj":"T8589"},{"id":"R5199","pred":"conj","subj":"T8589","obj":"T8571"},{"id":"R5200","pred":"compound","subj":"T8590","obj":"T8589"},{"id":"R5201","pred":"prep","subj":"T8591","obj":"T8589"},{"id":"R5202","pred":"pobj","subj":"T8592","obj":"T8591"},{"id":"R5203","pred":"punct","subj":"T8593","obj":"T8592"},{"id":"R5204","pred":"punct","subj":"T8594","obj":"T8592"},{"id":"R5205","pred":"punct","subj":"T8595","obj":"T8592"},{"id":"R5206","pred":"prep","subj":"T8596","obj":"T8592"},{"id":"R5207","pred":"pobj","subj":"T8597","obj":"T8596"},{"id":"R5208","pred":"punct","subj":"T8598","obj":"T8599"},{"id":"R5209","pred":"parataxis","subj":"T8599","obj":"T8589"},{"id":"R5210","pred":"punct","subj":"T8600","obj":"T8599"},{"id":"R5211","pred":"prep","subj":"T8601","obj":"T8571"},{"id":"R5212","pred":"amod","subj":"T8602","obj":"T8603"},{"id":"R5213","pred":"compound","subj":"T8603","obj":"T8604"},{"id":"R5214","pred":"pobj","subj":"T8604","obj":"T8601"},{"id":"R5215","pred":"punct","subj":"T8605","obj":"T8571"},{"id":"R5216","pred":"punct","subj":"T8607","obj":"T8608"},{"id":"R5217","pred":"meta","subj":"T8608","obj":"T8609"},{"id":"R5218","pred":"punct","subj":"T8610","obj":"T8608"},{"id":"R5219","pred":"prep","subj":"T8611","obj":"T8609"},{"id":"R5220","pred":"pobj","subj":"T8612","obj":"T8611"},{"id":"R5221","pred":"prep","subj":"T8613","obj":"T8609"},{"id":"R5222","pred":"det","subj":"T8614","obj":"T8615"},{"id":"R5223","pred":"pobj","subj":"T8615","obj":"T8613"},{"id":"R5224","pred":"compound","subj":"T8616","obj":"T8615"},{"id":"R5225","pred":"prep","subj":"T8617","obj":"T8615"},{"id":"R5226","pred":"nmod","subj":"T8618","obj":"T8619"},{"id":"R5227","pred":"pobj","subj":"T8619","obj":"T8617"},{"id":"R5228","pred":"punct","subj":"T8620","obj":"T8618"},{"id":"R5229","pred":"punct","subj":"T8621","obj":"T8618"},{"id":"R5230","pred":"punct","subj":"T8622","obj":"T8618"},{"id":"R5231","pred":"punct","subj":"T8623","obj":"T8609"},{"id":"R5232","pred":"amod","subj":"T8625","obj":"T8626"},{"id":"R5233","pred":"nsubjpass","subj":"T8626","obj":"T8628"},{"id":"R5234","pred":"amod","subj":"T8627","obj":"T8626"},{"id":"R5235","pred":"auxpass","subj":"T8629","obj":"T8628"},{"id":"R5236","pred":"prep","subj":"T8630","obj":"T8628"},{"id":"R5237","pred":"compound","subj":"T8631","obj":"T8632"},{"id":"R5238","pred":"pobj","subj":"T8632","obj":"T8630"},{"id":"R5239","pred":"punct","subj":"T8633","obj":"T8634"},{"id":"R5240","pred":"parataxis","subj":"T8634","obj":"T8628"},{"id":"R5241","pred":"nmod","subj":"T8635","obj":"T8634"},{"id":"R5242","pred":"punct","subj":"T8636","obj":"T8634"},{"id":"R5243","pred":"conj","subj":"T8637","obj":"T8634"},{"id":"R5244","pred":"punct","subj":"T8638","obj":"T8637"},{"id":"R5245","pred":"cc","subj":"T8639","obj":"T8637"},{"id":"R5246","pred":"conj","subj":"T8640","obj":"T8637"},{"id":"R5247","pred":"punct","subj":"T8641","obj":"T8634"},{"id":"R5248","pred":"prep","subj":"T8642","obj":"T8634"},{"id":"R5249","pred":"pobj","subj":"T8643","obj":"T8642"},{"id":"R5250","pred":"punct","subj":"T8644","obj":"T8634"},{"id":"R5251","pred":"punct","subj":"T8645","obj":"T8628"},{"id":"R5252","pred":"amod","subj":"T8647","obj":"T8648"},{"id":"R5253","pred":"nsubj","subj":"T8648","obj":"T8649"},{"id":"R5254","pred":"nummod","subj":"T8650","obj":"T8648"},{"id":"R5255","pred":"punct","subj":"T8651","obj":"T8652"},{"id":"R5256","pred":"parataxis","subj":"T8652","obj":"T8648"},{"id":"R5257","pred":"nummod","subj":"T8653","obj":"T8652"},{"id":"R5258","pred":"punct","subj":"T8654","obj":"T8652"},{"id":"R5259","pred":"nummod","subj":"T8655","obj":"T8656"},{"id":"R5260","pred":"dobj","subj":"T8656","obj":"T8649"},{"id":"R5261","pred":"amod","subj":"T8657","obj":"T8656"},{"id":"R5262","pred":"punct","subj":"T8658","obj":"T8649"},{"id":"R5263","pred":"mark","subj":"T8659","obj":"T8660"},{"id":"R5264","pred":"advcl","subj":"T8660","obj":"T8649"},{"id":"R5265","pred":"nsubj","subj":"T8661","obj":"T8660"},{"id":"R5266","pred":"nummod","subj":"T8662","obj":"T8661"},{"id":"R5267","pred":"cc","subj":"T8663","obj":"T8661"},{"id":"R5268","pred":"conj","subj":"T8664","obj":"T8661"},{"id":"R5269","pred":"nummod","subj":"T8665","obj":"T8664"},{"id":"R5270","pred":"dobj","subj":"T8666","obj":"T8660"},{"id":"R5271","pred":"punct","subj":"T8667","obj":"T8649"},{"id":"R5272","pred":"prep","subj":"T8669","obj":"T8670"},{"id":"R5273","pred":"pobj","subj":"T8671","obj":"T8669"},{"id":"R5274","pred":"punct","subj":"T8672","obj":"T8670"},{"id":"R5275","pred":"det","subj":"T8673","obj":"T8674"},{"id":"R5276","pred":"nsubjpass","subj":"T8674","obj":"T8670"},{"id":"R5277","pred":"amod","subj":"T8675","obj":"T8674"},{"id":"R5278","pred":"compound","subj":"T8676","obj":"T8674"},{"id":"R5279","pred":"punct","subj":"T8677","obj":"T8674"},{"id":"R5280","pred":"appos","subj":"T8678","obj":"T8674"},{"id":"R5281","pred":"punct","subj":"T8679","obj":"T8674"},{"id":"R5282","pred":"acl","subj":"T8680","obj":"T8674"},{"id":"R5283","pred":"oprd","subj":"T8681","obj":"T8680"},{"id":"R5284","pred":"cc","subj":"T8682","obj":"T8674"},{"id":"R5285","pred":"amod","subj":"T8683","obj":"T8684"},{"id":"R5286","pred":"conj","subj":"T8684","obj":"T8674"},{"id":"R5287","pred":"prep","subj":"T8685","obj":"T8684"},{"id":"R5288","pred":"nmod","subj":"T8686","obj":"T8687"},{"id":"R5289","pred":"pobj","subj":"T8687","obj":"T8685"},{"id":"R5290","pred":"punct","subj":"T8688","obj":"T8686"},{"id":"R5291","pred":"appos","subj":"T8689","obj":"T8686"},{"id":"R5292","pred":"punct","subj":"T8690","obj":"T8687"},{"id":"R5293","pred":"prep","subj":"T8691","obj":"T8687"},{"id":"R5294","pred":"amod","subj":"T8692","obj":"T8693"},{"id":"R5295","pred":"pobj","subj":"T8693","obj":"T8691"},{"id":"R5296","pred":"auxpass","subj":"T8694","obj":"T8670"},{"id":"R5297","pred":"punct","subj":"T8695","obj":"T8670"},{"id":"R5298","pred":"prep","subj":"T8696","obj":"T8670"},{"id":"R5299","pred":"prep","subj":"T8697","obj":"T8696"},{"id":"R5300","pred":"amod","subj":"T8698","obj":"T8699"},{"id":"R5301","pred":"pobj","subj":"T8699","obj":"T8697"},{"id":"R5302","pred":"prep","subj":"T8700","obj":"T8699"},{"id":"R5303","pred":"amod","subj":"T8701","obj":"T8702"},{"id":"R5304","pred":"pobj","subj":"T8702","obj":"T8700"},{"id":"R5305","pred":"punct","subj":"T8703","obj":"T8704"},{"id":"R5306","pred":"parataxis","subj":"T8704","obj":"T8702"},{"id":"R5307","pred":"punct","subj":"T8705","obj":"T8704"},{"id":"R5308","pred":"dep","subj":"T8706","obj":"T8707"},{"id":"R5309","pred":"relcl","subj":"T8707","obj":"T8699"},{"id":"R5310","pred":"det","subj":"T8708","obj":"T8709"},{"id":"R5311","pred":"dobj","subj":"T8709","obj":"T8707"},{"id":"R5312","pred":"compound","subj":"T8710","obj":"T8709"},{"id":"R5313","pred":"cc","subj":"T8711","obj":"T8707"},{"id":"R5314","pred":"conj","subj":"T8712","obj":"T8707"},{"id":"R5315","pred":"aux","subj":"T8713","obj":"T8714"},{"id":"R5316","pred":"xcomp","subj":"T8714","obj":"T8712"},{"id":"R5317","pred":"auxpass","subj":"T8715","obj":"T8714"},{"id":"R5318","pred":"prep","subj":"T8716","obj":"T8714"},{"id":"R5319","pred":"amod","subj":"T8717","obj":"T8718"},{"id":"R5320","pred":"pobj","subj":"T8718","obj":"T8716"},{"id":"R5321","pred":"punct","subj":"T8719","obj":"T8670"},{"id":"R5322","pred":"compound","subj":"T8721","obj":"T8722"},{"id":"R5323","pred":"nsubj","subj":"T8722","obj":"T8723"},{"id":"R5324","pred":"punct","subj":"T8724","obj":"T8723"},{"id":"R5325","pred":"nummod","subj":"T8725","obj":"T8723"},{"id":"R5326","pred":"punct","subj":"T8726","obj":"T8723"},{"id":"R5327","pred":"punct","subj":"T8728","obj":"T8729"},{"id":"R5328","pred":"meta","subj":"T8729","obj":"T8730"},{"id":"R5329","pred":"punct","subj":"T8731","obj":"T8729"},{"id":"R5330","pred":"amod","subj":"T8732","obj":"T8730"},{"id":"R5331","pred":"amod","subj":"T8733","obj":"T8730"},{"id":"R5332","pred":"prep","subj":"T8734","obj":"T8730"},{"id":"R5333","pred":"compound","subj":"T8735","obj":"T8736"},{"id":"R5334","pred":"pobj","subj":"T8736","obj":"T8734"},{"id":"R5335","pred":"punct","subj":"T8737","obj":"T8730"},{"id":"R5336","pred":"prep","subj":"T8738","obj":"T8730"},{"id":"R5337","pred":"det","subj":"T8739","obj":"T8740"},{"id":"R5338","pred":"pobj","subj":"T8740","obj":"T8738"},{"id":"R5339","pred":"nmod","subj":"T8741","obj":"T8740"},{"id":"R5340","pred":"punct","subj":"T8742","obj":"T8741"},{"id":"R5341","pred":"punct","subj":"T8743","obj":"T8741"},{"id":"R5342","pred":"punct","subj":"T8744","obj":"T8741"},{"id":"R5343","pred":"punct","subj":"T8745","obj":"T8730"},{"id":"R5344","pred":"acl","subj":"T8746","obj":"T8730"},{"id":"R5345","pred":"amod","subj":"T8747","obj":"T8748"},{"id":"R5346","pred":"dobj","subj":"T8748","obj":"T8746"},{"id":"R5347","pred":"nummod","subj":"T8749","obj":"T8750"},{"id":"R5348","pred":"nummod","subj":"T8750","obj":"T8748"},{"id":"R5349","pred":"punct","subj":"T8751","obj":"T8750"},{"id":"R5350","pred":"amod","subj":"T8752","obj":"T8748"},{"id":"R5351","pred":"prep","subj":"T8753","obj":"T8748"},{"id":"R5352","pred":"compound","subj":"T8754","obj":"T8755"},{"id":"R5353","pred":"pobj","subj":"T8755","obj":"T8753"},{"id":"R5354","pred":"punct","subj":"T8756","obj":"T8730"},{"id":"R5355","pred":"compound","subj":"T8758","obj":"T8759"},{"id":"R5356","pred":"nsubj","subj":"T8759","obj":"T8760"},{"id":"R5357","pred":"punct","subj":"T8761","obj":"T8760"},{"id":"R5358","pred":"nummod","subj":"T8762","obj":"T8760"},{"id":"R5359","pred":"punct","subj":"T8763","obj":"T8760"},{"id":"R5360","pred":"punct","subj":"T8765","obj":"T8766"},{"id":"R5361","pred":"meta","subj":"T8766","obj":"T8767"},{"id":"R5362","pred":"punct","subj":"T8768","obj":"T8766"},{"id":"R5363","pred":"amod","subj":"T8769","obj":"T8767"},{"id":"R5364","pred":"compound","subj":"T8770","obj":"T8767"},{"id":"R5365","pred":"punct","subj":"T8771","obj":"T8772"},{"id":"R5366","pred":"appos","subj":"T8772","obj":"T8767"},{"id":"R5367","pred":"punct","subj":"T8773","obj":"T8767"},{"id":"R5368","pred":"prep","subj":"T8774","obj":"T8767"},{"id":"R5369","pred":"amod","subj":"T8775","obj":"T8776"},{"id":"R5370","pred":"pobj","subj":"T8776","obj":"T8774"},{"id":"R5371","pred":"punct","subj":"T8777","obj":"T8778"},{"id":"R5372","pred":"parataxis","subj":"T8778","obj":"T8776"},{"id":"R5373","pred":"nsubj","subj":"T8779","obj":"T8778"},{"id":"R5374","pred":"nummod","subj":"T8780","obj":"T8781"},{"id":"R5375","pred":"dobj","subj":"T8781","obj":"T8778"},{"id":"R5376","pred":"punct","subj":"T8782","obj":"T8778"},{"id":"R5377","pred":"acl","subj":"T8783","obj":"T8776"},{"id":"R5378","pred":"prep","subj":"T8784","obj":"T8783"},{"id":"R5379","pred":"amod","subj":"T8785","obj":"T8786"},{"id":"R5380","pred":"pobj","subj":"T8786","obj":"T8784"},{"id":"R5381","pred":"prep","subj":"T8787","obj":"T8786"},{"id":"R5382","pred":"nmod","subj":"T8788","obj":"T8789"},{"id":"R5383","pred":"pobj","subj":"T8789","obj":"T8787"},{"id":"R5384","pred":"punct","subj":"T8790","obj":"T8788"},{"id":"R5385","pred":"punct","subj":"T8791","obj":"T8788"},{"id":"R5386","pred":"punct","subj":"T8792","obj":"T8788"},{"id":"R5387","pred":"prep","subj":"T8793","obj":"T8783"},{"id":"R5388","pred":"pobj","subj":"T8794","obj":"T8793"},{"id":"R5389","pred":"punct","subj":"T8795","obj":"T8767"},{"id":"R5390","pred":"nsubj","subj":"T8797","obj":"T8798"},{"id":"R5391","pred":"amod","subj":"T8799","obj":"T8800"},{"id":"R5392","pred":"dobj","subj":"T8800","obj":"T8798"},{"id":"R5393","pred":"acl","subj":"T8801","obj":"T8800"},{"id":"R5394","pred":"prep","subj":"T8802","obj":"T8801"},{"id":"R5395","pred":"det","subj":"T8803","obj":"T8804"},{"id":"R5396","pred":"pobj","subj":"T8804","obj":"T8802"},{"id":"R5397","pred":"amod","subj":"T8805","obj":"T8804"},{"id":"R5398","pred":"mark","subj":"T8806","obj":"T8807"},{"id":"R5399","pred":"advcl","subj":"T8807","obj":"T8798"},{"id":"R5400","pred":"det","subj":"T8808","obj":"T8809"},{"id":"R5401","pred":"nsubj","subj":"T8809","obj":"T8807"},{"id":"R5402","pred":"amod","subj":"T8810","obj":"T8809"},{"id":"R5403","pred":"punct","subj":"T8811","obj":"T8798"},{"id":"R5404","pred":"compound","subj":"T8813","obj":"T8814"},{"id":"R5405","pred":"nsubj","subj":"T8814","obj":"T8815"},{"id":"R5406","pred":"punct","subj":"T8816","obj":"T8815"},{"id":"R5407","pred":"nummod","subj":"T8817","obj":"T8815"},{"id":"R5408","pred":"punct","subj":"T8818","obj":"T8815"}],"text":"Transmission electron micrograph of Crx-/- retina at P21 (A and B), and scanning electron micrograph of Crx-/- at P10 (C) of outer segment layer. (A) Evidence of ciliogenesis in the photoreceptor layer of Crx-/- retina. Nonmotile connecting cilia were observed in cross section (arrowheads 1,2, and 3, for examples). Connecting cilium 1 (arrowhead 1) demonstrated seven microtuble doublets, while cilium 2 and cilium 3 exhibited nine. In A, a displaced cell nucleus (n) appearing pyknotic and abnormal deposition of matrix (mx) material of unknown identity were seen, along with large amounts of membranous vesicles (arrow) which filled the photoreceptor space and appeared to be released from inner segments. Scale bar = 3.7 μm. (B) Nonmotile connecting cilium in cross section, from a Crx-/- photoreceptor, demonstrating characteristic 9+0 radial array of microtubule doublets. Scale bar = 88 nm. (C) Scanning electron micrograph (SEM) of membranous vesicles (arrow shows one example) shed from inner segments of Crx-/- photoreceptors at P10. Figure shows inner segments viewed from the scleral side with the pigmented epithelium removed. Scale bar = 1 μm."}