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PMC:548520 / 6408-14858 JSONTXT

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2_test

Id Subject Object Predicate Lexical cue
15676071-10581037-12933274 241-243 10581037 denotes 34
15676071-10744971-12933275 7897-7899 10744971 denotes 10
15676071-10581037-12933276 7900-7902 10581037 denotes 34
15676071-11733058-12933277 7903-7905 11733058 denotes 35
15676071-9020854-12933278 8040-8042 9020854 denotes 29
15676071-6715580-12933279 8043-8045 6715580 denotes 30

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T2133 28-41 GO:0001750 denotes outer segment
T2134 28-47 UBERON:0003926 denotes outer segment layer
T2157 438-443 GO:0007567 denotes natal
T2158 463-466 PR_EXT:000005904 denotes Crx
T2159 466-467 SO_EXT:normal_or_wild_type_or_present denotes +
T2160 468-469 SO_EXT:normal_or_wild_type_or_present denotes +
T2161 470-484 CL:0000210 denotes photoreceptors
T2162 502-516 GO:0001750 denotes outer segments
T2163 534-537 PR_EXT:000005904 denotes Crx
T2164 537-538 SO_EXT:sequence_nullness_or_absence denotes -
T2165 539-540 SO_EXT:sequence_nullness_or_absence denotes -
T2166 541-548 UBERON:0000966 denotes retinas
T2167 577-590 GO:0001750 denotes outer segment
T2168 577-596 UBERON:0003926 denotes outer segment layer
T2169 610-613 PR_EXT:000005904 denotes Crx
T2170 613-614 SO_EXT:sequence_nullness_or_absence denotes -
T2171 615-616 SO_EXT:sequence_nullness_or_absence denotes -
T2172 617-631 CL:0000210 denotes photoreceptors
T2173 636-650 GO:0001917 denotes inner segments
T2174 683-696 CL:0000210 denotes photoreceptor
T2175 717-720 PR_EXT:000005904 denotes Crx
T2176 721-727 SO_EXT:sequence_altered_entity denotes mutant
T2177 737-751 GO:0001917 denotes inner segments
T2178 814-828 GO:0001917 denotes inner segments
T2179 855-870 GO_RO_EXT:developmental_differentiation_process denotes differentiation
T2180 901-913 GO:0005739 denotes mitochondria
T2181 964-977 GO:0001917 denotes inner segment
T2182 989-994 GO:0019835 denotes lysis
T2183 1032-1040 GO:0005773 denotes vacuoles
T2184 1053-1065 GO:0005739 denotes mitochondria
T2185 1645-1646 UBERON:0000483 denotes h
T2186 1646-1647 GO:0001750 denotes o
T2187 1647-1648 GO:0001750 denotes t
T2188 1648-1649 UBERON:0001789 denotes o
T2189 1649-1651 UBERON:0001789 denotes re
T2190 1650-1651 GO:0005634 denotes e
T2191 1651-1657 CL:0000210 denotes ceptor
T2192 1658-1659 GO:0005634 denotes i
T2193 1661-1663 CHEBI:10545 denotes er
T2194 1664-1671 GO:0001750 denotes segment
T2195 1664-1671 UBERON:0003926 denotes segment
T2196 1671-1673 _FRAGMENT denotes s
T2197 1673-1674 GO:0005739 denotes a
T2234 3751-3752 SO_EXT:sequence_nullness_or_absence denotes -
T2235 3753-3760 UBERON:0000966 denotes retinas
T2236 3810-3823 GO:0001750 denotes outer segment
T2237 3810-3829 UBERON:0003926 denotes outer segment layer
T2238 3864-3870 GO:0031012 denotes matrix
T2239 3949-3955 GO:0005634 denotes nuclei
T2240 4026-4032 GO:0005634 denotes nuclei
T2241 4042-4050 GO:0030263 denotes pyknotic
T2242 4102-4117 GO:0000792 denotes heterochromatin
T2243 4137-4151 CL:0000210 denotes photoreceptors
T2244 4220-4234 CL:0000210 denotes photoreceptors
T2245 4279-4292 GO:0001750 denotes outer segment
T2246 4279-4298 UBERON:0003926 denotes outer segment layer
T2247 4319-4327 GO:0031982 denotes vesicles
T2248 4411-4425 GO:0001917 denotes inner segments
T2249 4439-4447 CHEBI:10545 denotes electron
T2250 4512-4526 GO:0001917 denotes inner segments
T2251 4584-4600 _FRAGMENT denotes morphogenesis of
T2252 4608-4622 GO:0008594 denotes photoreceptors
T2253 4601-4604 PR_EXT:000005904 denotes Crx
T2254 4604-4605 SO_EXT:sequence_nullness_or_absence denotes -
T2255 4606-4607 SO_EXT:sequence_nullness_or_absence denotes -
T2256 4608-4622 CL:0000210 denotes photoreceptors
T2257 4639-4652 GO:0001750 denotes outer segment
T2258 4639-4658 UBERON:0003926 denotes outer segment layer
T2259 4682-4690 CHEBI:10545 denotes electron
T2260 4736-4739 PR_EXT:000005904 denotes Crx
T2261 4739-4740 SO_EXT:normal_or_wild_type_or_present denotes +
T2262 4741-4742 SO_EXT:normal_or_wild_type_or_present denotes +
T2263 4743-4750 UBERON:0000966 denotes retinas
T2264 4752-4765 CL:0000210 denotes photoreceptor
T2265 4752-4780 GO:0001917 denotes photoreceptor inner segments
T2266 4782-4798 GO:0032391 denotes connecting cilia
T2267 4826-4839 GO:0001750 denotes outer segment
T2268 4876-4879 PR_EXT:000005904 denotes Crx
T2269 4879-4880 SO_EXT:sequence_nullness_or_absence denotes -
T2270 4881-4882 SO_EXT:sequence_nullness_or_absence denotes -
T2271 4883-4889 UBERON:0000966 denotes retina
T2272 4911-4928 GO:0032391 denotes connecting cilium
T2273 4953-4967 GO:0001917 denotes inner segments
T2274 5065-5073 CHEBI:10545 denotes electron
T2275 5159-5162 PR_EXT:000005904 denotes Crx
T2276 5162-5163 SO_EXT:normal_or_wild_type_or_present denotes +
T2277 5164-5165 SO_EXT:normal_or_wild_type_or_present denotes +
T2278 5170-5173 PR_EXT:000005904 denotes Crx
T2279 5173-5174 SO_EXT:sequence_nullness_or_absence denotes -
T2280 5175-5176 SO_EXT:sequence_nullness_or_absence denotes -
T2281 5177-5191 CL:0000210 denotes photoreceptors
T2282 5212-5226 GO:0001750 denotes outer segments
T2283 5241-5244 PR_EXT:000005904 denotes Crx
T2284 5244-5245 SO_EXT:normal_or_wild_type_or_present denotes +
T2285 5246-5247 SO_EXT:normal_or_wild_type_or_present denotes +
T2286 5248-5262 CL:0000210 denotes photoreceptors
T2287 5324-5328 GO:0045177 denotes apex
T2288 5349-5352 PR_EXT:000005904 denotes Crx
T2289 5352-5353 SO_EXT:sequence_nullness_or_absence denotes -
T2290 5354-5355 SO_EXT:sequence_nullness_or_absence denotes -
T2291 5356-5363 UBERON:0000966 denotes retinae
T2292 5386-5400 CL:0000210 denotes photoreceptors
T2293 5428-5444 GO:0032391 denotes connecting cilia
T2294 5453-5467 GO:0001750 denotes outer segments
T2295 5499-5502 PR_EXT:000005904 denotes Crx
T2296 5502-5503 SO_EXT:sequence_nullness_or_absence denotes -
T2297 5504-5505 SO_EXT:sequence_nullness_or_absence denotes -
T2298 5506-5520 CL:0000210 denotes photoreceptors
T2299 5575-5592 GO:0032391 denotes connecting cilium
T2300 5643-5656 GO:0001750 denotes outer segment
T2301 5743-5757 GO:0001750 denotes outer segments
T2302 5784-5787 PR_EXT:000005904 denotes Crx
T2303 5787-5788 SO_EXT:normal_or_wild_type_or_present denotes +
T2304 5789-5790 SO_EXT:normal_or_wild_type_or_present denotes +
T2305 5853-5856 PR_EXT:000005904 denotes Crx
T2306 5856-5857 SO_EXT:sequence_nullness_or_absence denotes -
T2307 5858-5859 SO_EXT:sequence_nullness_or_absence denotes -
T2308 5860-5874 CL:0000210 denotes photoreceptors
T2309 5891-5907 GO:0032391 denotes connecting cilia
T2310 5958-5961 PR_EXT:000005904 denotes Crx
T2311 5961-5962 SO_EXT:sequence_nullness_or_absence denotes -
T2312 5963-5964 SO_EXT:sequence_nullness_or_absence denotes -
T2313 5965-5979 CL:0000210 denotes photoreceptors
T2314 6173-6186 GO:0001750 denotes outer segment
T2315 6204-6207 PR_EXT:000005904 denotes Crx
T2316 6208-6214 SO_EXT:sequence_altered_entity_or_alteration_process denotes mutant
T2317 6215-6220 NCBITaxon:10088 denotes mouse
T2318 6259-6272 CL:0000210 denotes photoreceptor
T2319 6273-6282 GO:0042995 denotes appendage
T2320 6310-6323 GO:0001750 denotes outer segment
T2341 7820-7825 SO_EXT:0000704 denotes genes
T2342 7832-7842 GO:0010467 denotes expression
T2343 7860-7873 GO_EXT:negative_regulation denotes downregulated
T2344 7881-7884 PR_EXT:000005904 denotes Crx
T2345 7884-7885 SO_EXT:sequence_nullness_or_absence denotes -
T2346 7886-7887 SO_EXT:sequence_nullness_or_absence denotes -
T2347 7888-7895 UBERON:0000966 denotes retinae
T2348 7925-7934 SO_EXT:sequence_alteration_entity_or_process denotes mutations
T2349 7952-7957 SO_EXT:0000704 denotes genes
T2350 8024-8038 GO:0001750 denotes outer segments
T2351 8048-8062 CL:0000210 denotes Photoreceptors
T2352 8078-8084 SO_EXT:sequence_altered_entity_or_alteration_process denotes mutant
T2353 8085-8089 NCBITaxon:10088 denotes mice
T2354 8115-8122 UBERON:0001773 denotes scleral
T2355 8155-8158 PR_EXT:000005904 denotes Crx
T2356 8158-8159 SO_EXT:sequence_nullness_or_absence denotes -
T2357 8160-8161 SO_EXT:sequence_nullness_or_absence denotes -
T2358 8162-8176 CL:0000210 denotes photoreceptors
T8245 1258-1261 UBERON:0001789 denotes onl
T8246 1263-1282 UBERON:0001789 denotes outer nuclear layer
T8247 1269-1276 GO:0005634 denotes nuclear
T8248 1288-1301 CL:0000210 denotes photoreceptor
T8249 1302-1308 GO:0005634 denotes nuclei
T8347 1363-1371 CHEBI:10545 denotes electron
T8348 1390-1403 GO:0001750 denotes outer segment
T8349 1390-1409 UBERON:0003926 denotes outer segment layer
T8350 1413-1416 PR_EXT:000005904 denotes Crx
T8351 1416-1417 SO_EXT:sequence_nullness_or_absence denotes -
T8352 1418-1419 SO_EXT:sequence_nullness_or_absence denotes -
T8353 1420-1426 UBERON:0000966 denotes retina
T8354 1435-1452 _FRAGMENT denotes Inner segments of
T8355 1460-1474 GO:0001917 denotes photoreceptors
T8356 1453-1456 PR_EXT:000005904 denotes Crx
T8357 1456-1457 SO_EXT:sequence_nullness_or_absence denotes -
T8358 1458-1459 SO_EXT:sequence_nullness_or_absence denotes -
T8359 1460-1474 CL:0000210 denotes photoreceptors
T8360 1492-1504 GO:0005739 denotes mitochondria
T8361 1506-1507 GO:0005739 denotes m
T8362 1534-1537 PR_EXT:000005904 denotes Crx
T8363 1537-1538 SO_EXT:normal_or_wild_type_or_present denotes +
T8364 1539-1540 SO_EXT:normal_or_wild_type_or_present denotes +
T8365 1558-1567 CHEBI_EXT:26130 denotes pigmented
T8366 1568-1578 UBERON:0000483 denotes epithelium
T8367 1580-1582 GO:0001917 denotes is
T8368 1584-1598 GO:0001917 denotes inner segments
T8369 1600-1603 UBERON:0001789 denotes onl
T8370 1605-1624 UBERON:0001789 denotes outer nuclear layer
T8371 1611-1618 GO:0005634 denotes nuclear
T8520 2545-2553 CHEBI:10545 denotes electron
T8521 2568-2571 PR_EXT:000005904 denotes Crx
T8522 2571-2572 SO_EXT:sequence_nullness_or_absence denotes -
T8523 2573-2574 SO_EXT:sequence_nullness_or_absence denotes -
T8524 2575-2581 UBERON:0000966 denotes retina
T8525 2613-2621 CHEBI:10545 denotes electron
T8526 2636-2639 PR_EXT:000005904 denotes Crx
T8527 2639-2640 SO_EXT:sequence_nullness_or_absence denotes -
T8528 2641-2642 SO_EXT:sequence_nullness_or_absence denotes -
T8529 2657-2670 GO:0001750 denotes outer segment
T8530 2657-2676 UBERON:0003926 denotes outer segment layer
T8531 2694-2706 GO:0042384 denotes ciliogenesis
T8532 2714-2727 CL:0000210 denotes photoreceptor
T8533 2714-2736 _FRAGMENT denotes photoreceptor layer of
T8534 2744-2750 UBERON:0001787 denotes retina
T8535 2737-2740 PR_EXT:000005904 denotes Crx
T8536 2740-2741 SO_EXT:sequence_nullness_or_absence denotes -
T8537 2742-2743 SO_EXT:sequence_nullness_or_absence denotes -
T8538 2752-2778 GO:0032391 denotes Nonmotile connecting cilia
T8539 2849-2866 GO:0032391 denotes Connecting cilium
T8540 2902-2912 GO:0005874 denotes microtuble
T8541 2929-2935 GO:0005929 denotes cilium
T8542 2942-2948 GO:0005929 denotes cilium
T8543 2985-2989 CL_GO_EXT:cell denotes cell
T8544 2985-2997 GO:0005634 denotes cell nucleus
T8545 2999-3000 GO:0005634 denotes n
T8546 3012-3020 GO:0030263 denotes pyknotic
T8547 3048-3054 GO:0031012 denotes matrix
T8548 3056-3058 GO:0031012 denotes mx
T8549 3128-3147 GO:0031988 denotes membranous vesicles
T8550 3173-3186 CL:0000210 denotes photoreceptor
T8551 3212-3220 GO_EXT:biological_release denotes released
T8552 3226-3240 GO:0001917 denotes inner segments
T8553 3266-3293 GO:0032391 denotes Nonmotile connecting cilium
T8554 3319-3322 PR_EXT:000005904 denotes Crx
T8555 3322-3323 SO_EXT:sequence_nullness_or_absence denotes -
T8556 3324-3325 SO_EXT:sequence_nullness_or_absence denotes -
T8557 3326-3339 CL:0000210 denotes photoreceptor
T8558 3390-3401 GO:0005874 denotes microtubule
T8559 3444-3452 CHEBI:10545 denotes electron
T8560 3473-3492 GO:0031988 denotes membranous vesicles
T8561 3529-3543 GO:0001917 denotes inner segments
T8562 3547-3550 PR_EXT:000005904 denotes Crx
T8563 3550-3551 SO_EXT:sequence_nullness_or_absence denotes -
T8564 3552-3553 SO_EXT:sequence_nullness_or_absence denotes -
T8565 3554-3568 CL:0000210 denotes photoreceptors
T8566 3590-3604 GO:0001917 denotes inner segments
T8567 3621-3628 UBERON:0001773 denotes scleral
T8568 3643-3652 CHEBI_EXT:26130 denotes pigmented
T8569 3653-3663 UBERON:0000483 denotes epithelium
T8875 6345-6358 GO:0001750 denotes Outer segment
T8876 6359-6372 GO:0009653 denotes morphogenesis
T8877 6376-6379 PR_EXT:000005904 denotes Crx
T8878 6379-6380 SO_EXT:sequence_nullness_or_absence denotes -
T8879 6381-6382 SO_EXT:sequence_nullness_or_absence denotes -
T8880 6383-6397 CL:0000210 denotes photoreceptors
T8881 6408-6416 CHEBI:10545 denotes electron
T8882 6442-6456 CL:0000210 denotes photoreceptors
T8883 6473-6480 UBERON:0001773 denotes scleral
T8884 6495-6504 CHEBI_EXT:26130 denotes pigmented
T8885 6505-6515 UBERON:0000483 denotes epithelium
T8886 6548-6551 PR_EXT:000005904 denotes Crx
T8887 6551-6552 SO_EXT:normal_or_wild_type_or_present denotes +
T8888 6553-6554 SO_EXT:normal_or_wild_type_or_present denotes +
T8889 6573-6576 PR_EXT:000005904 denotes Crx
T8890 6576-6577 SO_EXT:sequence_nullness_or_absence denotes -
T8891 6578-6579 SO_EXT:sequence_nullness_or_absence denotes -
T8892 6606-6609 PR_EXT:000005904 denotes Crx
T8893 6609-6610 SO_EXT:normal_or_wild_type_or_present denotes +
T8894 6611-6612 SO_EXT:normal_or_wild_type_or_present denotes +
T8895 6613-6619 UBERON:0000966 denotes retina
T8896 6630-6646 GO:0032391 denotes connecting cilia
T8897 6651-6653 GO:0032391 denotes cc
T8898 6691-6705 GO:0001750 denotes outer segments
T8899 6720-6723 PR_EXT:000005904 denotes Crx
T8900 6723-6724 SO_EXT:normal_or_wild_type_or_present denotes +
T8901 6725-6726 SO_EXT:normal_or_wild_type_or_present denotes +
T8902 6727-6740 GO:0001750 denotes outer segment
T8903 6771-6785 GO:0001750 denotes outer segments
T8904 6819-6821 GO:0001750 denotes os
T8905 6847-6849 GO:0001750 denotes os
T8906 6855-6858 PR_EXT:000005904 denotes Crx
T8907 6858-6859 SO_EXT:sequence_nullness_or_absence denotes -
T8908 6860-6861 SO_EXT:sequence_nullness_or_absence denotes -
T8909 6862-6876 CL:0000210 denotes photoreceptors
T8910 6882-6898 GO:0032391 denotes connecting cilia
T8911 6938-6954 GO:0032391 denotes connecting cilia
T8912 7003-7016 GO:0001750 denotes outer segment
T8913 7044-7061 GO:0032391 denotes connecting cilium
T8914 7072-7074 GO:0032391 denotes cc
T8915 7108-7111 PR_EXT:000005904 denotes Crx
T8916 7111-7112 SO_EXT:normal_or_wild_type_or_present denotes +
T8917 7113-7114 SO_EXT:normal_or_wild_type_or_present denotes +
T8918 7165-7181 GO:0032391 denotes connecting cilia
T8919 7195-7198 PR_EXT:000005904 denotes Crx
T8920 7198-7199 SO_EXT:sequence_nullness_or_absence denotes -
T8921 7200-7201 SO_EXT:sequence_nullness_or_absence denotes -
T8922 7206-7208 GO:0032391 denotes cc
T9180 7253-7261 CHEBI:10545 denotes electron
T9181 7277-7280 PR_EXT:000005904 denotes Crx
T9182 7280-7281 SO_EXT:sequence_nullness_or_absence denotes -
T9183 7282-7283 SO_EXT:sequence_nullness_or_absence denotes -
T9184 7284-7298 CL:0000210 denotes photoreceptors
T9185 7306-7319 CL:0000210 denotes photoreceptor
T9186 7306-7325 UBERON:0001787 denotes photoreceptor layer
T9187 7337-7350 CL:0000210 denotes Photoreceptor
T9188 7337-7359 _FRAGMENT denotes Photoreceptor layer of
T9189 7367-7373 UBERON:0001787 denotes retina
T9190 7360-7363 PR_EXT:000005904 denotes Crx
T9191 7363-7364 SO_EXT:normal_or_wild_type_or_present denotes +
T9192 7365-7366 SO_EXT:normal_or_wild_type_or_present denotes +
T9193 7396-7409 GO:0001750 denotes outer segment
T9194 7443-7456 CL:0000210 denotes photoreceptor
T9195 7443-7473 GO:0032391 denotes photoreceptor connecting cilia
T9196 7475-7477 GO:0032391 denotes cc
T9197 7484-7487 PR_EXT:000005904 denotes Crx
T9198 7487-7488 SO_EXT:sequence_nullness_or_absence denotes -
T9199 7489-7490 SO_EXT:sequence_nullness_or_absence denotes -
T9200 7491-7505 CL:0000210 denotes photoreceptors
T9201 7516-7532 GO:0032391 denotes connecting cilia
T9202 7534-7536 GO:0032391 denotes cc
T9203 7576-7589 GO:0001750 denotes outer segment
T9304 8237-8245 CHEBI:10545 denotes electron
T9305 8260-8270 PR_EXT:peripherin denotes peripherin
T9306 8270-8271 SO_EXT:sequence_nullness_or_absence denotes -
T9307 8272-8273 SO_EXT:sequence_nullness_or_absence denotes -
T9308 8282-8291 PR_EXT:000001245 denotes rhodopsin
T9309 8291-8292 SO_EXT:sequence_nullness_or_absence denotes -
T9310 8293-8294 SO_EXT:sequence_nullness_or_absence denotes -
T9311 8299-8313 CL:0000210 denotes photoreceptors
T9312 8338-8345 UBERON:0001773 denotes scleral
T9313 8360-8369 CHEBI_EXT:26130 denotes pigmented
T9314 8370-8380 UBERON:0000483 denotes epithelium
T9315 8390-8392 GO:0032391 denotes cc
T9316 8394-8411 GO:0032391 denotes connecting cilium
T9317 8413-8415 GO:0001917 denotes is
T9318 8417-8430 GO:0001917 denotes inner segment
T8230 1107-1115 CHEBI:10545 denotes electron
T8231 1140-1146 UBERON:0000966 denotes retina
T8232 1161-1164 PR_EXT:000005904 denotes Crx
T8233 1164-1165 SO_EXT:normal_or_wild_type_or_present denotes +
T8234 1166-1167 SO_EXT:normal_or_wild_type_or_present denotes +
T8235 1176-1179 PR_EXT:000005904 denotes Crx
T8236 1179-1180 SO_EXT:sequence_nullness_or_absence denotes -
T8237 1181-1182 SO_EXT:sequence_nullness_or_absence denotes -
T8238 1183-1190 UBERON:0000966 denotes retinas
T8239 1196-1205 CHEBI_EXT:26130 denotes pigmented
T8240 1206-1216 UBERON:0000483 denotes epithelium
T8241 1218-1220 GO:0001750 denotes os
T8242 1222-1236 GO:0001750 denotes outer segments
T8243 1238-1240 GO:0001917 denotes is
T8244 1242-1256 GO:0001917 denotes inner segments
T2135 51-54 PR_EXT:000005904 denotes Crx
T2136 54-55 SO_EXT:sequence_nullness_or_absence denotes -
T2137 56-57 SO_EXT:sequence_nullness_or_absence denotes -
T2138 58-62 NCBITaxon:10088 denotes mice
T2139 114-118 NCBITaxon:10088 denotes mice
T2140 147-150 PR_EXT:000005904 denotes Crx
T2141 150-151 SO_EXT:sequence_nullness_or_absence denotes -
T2142 152-153 SO_EXT:sequence_nullness_or_absence denotes -
T2143 171-178 SO_EXT:sequence_deletion_process denotes deleted
T2144 200-203 PR_EXT:000005904 denotes Crx
T2145 203-204 SO_EXT:sequence_nullness_or_absence denotes -
T2146 205-206 SO_EXT:sequence_nullness_or_absence denotes -
T2147 207-211 NCBITaxon:10088 denotes mice
T2148 306-309 PR_EXT:000005904 denotes Crx
T2149 313-326 CL:0000210 denotes photoreceptor
T2150 313-340 GO:0008594 denotes photoreceptor morphogenesis
T2151 352-359 UBERON:0000966 denotes retinae
T2152 365-368 PR_EXT:000005904 denotes Crx
T2153 368-369 SO_EXT:sequence_nullness_or_absence denotes -
T2154 370-371 SO_EXT:sequence_nullness_or_absence denotes -
T2155 372-376 NCBITaxon:10088 denotes mice
T2156 410-418 CHEBI:10545 denotes electron
T2198 1679-1681 CHEBI_EXT:26130 denotes te
T2199 1681-1691 GO:0001917 denotes r segments
T2200 1692-1695 UBERON:0001789 denotes are
T2201 1692-1694 GO:0005634 denotes ar
T2202 1708-1736 GO:0032391 denotes non-motile connecting cilium
T2203 1789-1800 GO:0005874 denotes microtubule
T2204 1851-1854 PR_EXT:000005904 denotes Crx
T2205 1854-1855 SO_EXT:sequence_nullness_or_absence denotes -
T2206 1856-1857 SO_EXT:sequence_nullness_or_absence denotes -
T2207 1858-1865 UBERON:0000966 denotes retinas
T2208 1894-1910 GO:0032391 denotes connecting cilia
T2209 1956-1972 GO:0032391 denotes connecting cilia
T2210 2020-2031 GO:0005874 denotes microtubule
T2211 2073-2090 GO:0032391 denotes connecting cilium
T2212 2291-2304 GO:0001917 denotes inner segment
T2213 2316-2328 GO:0042384 denotes ciliogenesis
T2214 2355-2358 PR_EXT:000005904 denotes Crx
T2215 2358-2359 SO_EXT:sequence_nullness_or_absence denotes -
T2216 2360-2361 SO_EXT:sequence_nullness_or_absence denotes -
T2217 2362-2376 CL:0000210 denotes photoreceptors
T2218 2390-2393 PR_EXT:000005904 denotes Crx
T2219 2393-2394 SO_EXT:sequence_nullness_or_absence denotes -
T2220 2395-2396 SO_EXT:sequence_nullness_or_absence denotes -
T2221 2397-2404 UBERON:0000966 denotes retinas
T2222 2409-2437 UBERON:0001782 denotes retinal pigmented epithelium
T2223 2417-2426 CHEBI_EXT:26130 denotes pigmented
T2224 3698-3700 GO:0030263 denotes ti
T2225 3703-3704 GO:0031012 denotes t
T2226 3710-3711 GO:0031988 denotes c
T2227 3713-3714 CL:0000210 denotes p
T2228 3715-3716 GO:0005874 denotes e
T2229 3720-3723 GO:0031988 denotes bse
T2230 3724-3726 CL:0000210 denotes ce
T2231 3731-3744 GO:0001750 denotes uter segments
T2232 3746-3749 PR_EXT:000005904 denotes Crx
T2233 3749-3750 SO_EXT:sequence_nullness_or_absence denotes -
T2321 7640-7641 GO:0001750 denotes n
T2322 7642-7643 CHEBI:10545 denotes l
T2323 7647-7648 GO:0001750 denotes t
T2324 7657-7658 UBERON:0001787 denotes l
T2325 7658-7659 CL:0000210 denotes o
T2326 7658-7659 _FRAGMENT denotes o
T2327 7679-7682 PR_EXT:000005904 denotes Crx
T2328 7682-7683 SO_EXT:sequence_nullness_or_absence denotes -
T2329 7684-7685 SO_EXT:sequence_nullness_or_absence denotes -
T2330 7686-7700 CL:0000210 denotes photoreceptors
T2331 7717-7726 PR_EXT:000001245 denotes rhodopsin
T2332 7726-7727 SO_EXT:sequence_nullness_or_absence denotes -
T2333 7728-7729 SO_EXT:sequence_nullness_or_absence denotes -
T2334 7734-7744 PR_EXT:peripherin denotes peripherin
T2335 7744-7745 SO_EXT:sequence_nullness_or_absence denotes -
T2336 7746-7747 SO_EXT:sequence_nullness_or_absence denotes -
T2337 7748-7762 CL:0000210 denotes photoreceptors
T2338 7764-7773 PR_EXT:000001245 denotes Rhodopsin
T2339 7778-7788 PR_EXT:peripherin denotes peripherin
T2340 7797-7810 CL:0000210 denotes photoreceptor
R5117 T8355 T8354 _lexicallyChainedTo photoreceptors,Inner segments of
R5180 T8534 T8533 _lexicallyChainedTo retina,photoreceptor layer of
R5615 T9189 T9188 _lexicallyChainedTo retina,Photoreceptor layer of
R1143 T2252 T2251 _lexicallyChainedTo photoreceptors,morphogenesis of

craft-ca-core-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T1970 28-41 GO:0001750 denotes outer segment
T1971 28-47 UBERON:0003926 denotes outer segment layer
T1972 51-54 PR:000005904 denotes Crx
T1973 58-62 NCBITaxon:10088 denotes mice
T1974 114-118 NCBITaxon:10088 denotes mice
T1975 147-150 PR:000005904 denotes Crx
T1976 200-203 PR:000005904 denotes Crx
T1977 207-211 NCBITaxon:10088 denotes mice
T1978 306-309 PR:000005904 denotes Crx
T1979 313-326 CL:0000210 denotes photoreceptor
T1980 313-340 GO:0008594 denotes photoreceptor morphogenesis
T1981 352-359 UBERON:0000966 denotes retinae
T1982 365-368 PR:000005904 denotes Crx
T1983 372-376 NCBITaxon:10088 denotes mice
T1984 410-418 CHEBI:10545 denotes electron
T1985 438-443 GO:0007567 denotes natal
T1986 463-466 PR:000005904 denotes Crx
T1987 470-484 CL:0000210 denotes photoreceptors
T1988 502-516 GO:0001750 denotes outer segments
T1989 534-537 PR:000005904 denotes Crx
T1990 541-548 UBERON:0000966 denotes retinas
T1991 577-590 GO:0001750 denotes outer segment
T1992 577-596 UBERON:0003926 denotes outer segment layer
T1993 610-613 PR:000005904 denotes Crx
T1994 617-631 CL:0000210 denotes photoreceptors
T1995 636-650 GO:0001917 denotes inner segments
T1996 683-696 CL:0000210 denotes photoreceptor
T1997 717-720 PR:000005904 denotes Crx
T1998 737-751 GO:0001917 denotes inner segments
T1999 814-828 GO:0001917 denotes inner segments
T2000 901-913 GO:0005739 denotes mitochondria
T2001 964-977 GO:0001917 denotes inner segment
T2002 989-994 GO:0019835 denotes lysis
T2003 1032-1040 GO:0005773 denotes vacuoles
T2004 1053-1065 GO:0005739 denotes mitochondria
T2005 1645-1646 UBERON:0000483 denotes h
T2006 1646-1647 GO:0001750 denotes o
T2007 1647-1648 GO:0001750 denotes t
T2051 3949-3955 GO:0005634 denotes nuclei
T2052 4026-4032 GO:0005634 denotes nuclei
T2053 4042-4050 GO:0030263 denotes pyknotic
T2054 4102-4117 GO:0000792 denotes heterochromatin
T2055 4137-4151 CL:0000210 denotes photoreceptors
T2056 4220-4234 CL:0000210 denotes photoreceptors
T2090 5386-5400 CL:0000210 denotes photoreceptors
T2091 5428-5444 GO:0032391 denotes connecting cilia
T2092 5453-5467 GO:0001750 denotes outer segments
T2093 5499-5502 PR:000005904 denotes Crx
T2094 5506-5520 CL:0000210 denotes photoreceptors
T2095 5575-5592 GO:0032391 denotes connecting cilium
T2096 5643-5656 GO:0001750 denotes outer segment
T2097 5743-5757 GO:0001750 denotes outer segments
T2098 5784-5787 PR:000005904 denotes Crx
T2099 5853-5856 PR:000005904 denotes Crx
T2100 5860-5874 CL:0000210 denotes photoreceptors
T2101 5891-5907 GO:0032391 denotes connecting cilia
T2102 5958-5961 PR:000005904 denotes Crx
T2103 5965-5979 CL:0000210 denotes photoreceptors
T2104 6173-6186 GO:0001750 denotes outer segment
T2105 6204-6207 PR:000005904 denotes Crx
T2106 6215-6220 NCBITaxon:10088 denotes mouse
T2107 6259-6272 CL:0000210 denotes photoreceptor
T2108 6273-6282 GO:0042995 denotes appendage
T2109 6310-6323 GO:0001750 denotes outer segment
T2110 7640-7641 GO:0001750 denotes n
T2111 7642-7643 CHEBI:10545 denotes l
T2112 7647-7648 GO:0001750 denotes t
T2113 7657-7658 UBERON:0001787 denotes l
T2114 7658-7659 CL:0000210 denotes o
T2115 7658-7659 _FRAGMENT denotes o
T2124 7881-7884 PR:000005904 denotes Crx
T2125 7888-7895 UBERON:0000966 denotes retinae
T2127 8024-8038 GO:0001750 denotes outer segments
T2128 8048-8062 CL:0000210 denotes Photoreceptors
T2129 8085-8089 NCBITaxon:10088 denotes mice
T2130 8115-8122 UBERON:0001773 denotes scleral
T2131 8155-8158 PR:000005904 denotes Crx
T2132 8162-8176 CL:0000210 denotes photoreceptors
T8343 1584-1598 GO:0001917 denotes inner segments
T8344 1600-1603 UBERON:0001789 denotes onl
T8345 1605-1624 UBERON:0001789 denotes outer nuclear layer
T8346 1611-1618 GO:0005634 denotes nuclear
T8482 2545-2553 CHEBI:10545 denotes electron
T8483 2568-2571 PR:000005904 denotes Crx
T8484 2575-2581 UBERON:0000966 denotes retina
T8485 2613-2621 CHEBI:10545 denotes electron
T8486 2636-2639 PR:000005904 denotes Crx
T8487 2657-2670 GO:0001750 denotes outer segment
T8488 2657-2676 UBERON:0003926 denotes outer segment layer
T8489 2694-2706 GO:0042384 denotes ciliogenesis
T8490 2714-2727 CL:0000210 denotes photoreceptor
T8491 2714-2736 _FRAGMENT denotes photoreceptor layer of
T8492 2744-2750 UBERON:0001787 denotes retina
T8493 2737-2740 PR:000005904 denotes Crx
T8494 2752-2778 GO:0032391 denotes Nonmotile connecting cilia
T8495 2849-2866 GO:0032391 denotes Connecting cilium
T8496 2902-2912 GO:0005874 denotes microtuble
T8497 2929-2935 GO:0005929 denotes cilium
T8498 2942-2948 GO:0005929 denotes cilium
T8499 2985-2997 GO:0005634 denotes cell nucleus
T8500 2999-3000 GO:0005634 denotes n
T8501 3012-3020 GO:0030263 denotes pyknotic
T8502 3048-3054 GO:0031012 denotes matrix
T8503 3056-3058 GO:0031012 denotes mx
T8504 3128-3147 GO:0031988 denotes membranous vesicles
T8505 3173-3186 CL:0000210 denotes photoreceptor
T8506 3226-3240 GO:0001917 denotes inner segments
T8507 3266-3293 GO:0032391 denotes Nonmotile connecting cilium
T8508 3319-3322 PR:000005904 denotes Crx
T8509 3326-3339 CL:0000210 denotes photoreceptor
T8510 3390-3401 GO:0005874 denotes microtubule
T8511 3444-3452 CHEBI:10545 denotes electron
T8512 3473-3492 GO:0031988 denotes membranous vesicles
T8513 3529-3543 GO:0001917 denotes inner segments
T8514 3547-3550 PR:000005904 denotes Crx
T8515 3554-3568 CL:0000210 denotes photoreceptors
T8516 3590-3604 GO:0001917 denotes inner segments
T8517 3621-3628 UBERON:0001773 denotes scleral
T8518 3643-3652 CHEBI:26130 denotes pigmented
T8519 3653-3663 UBERON:0000483 denotes epithelium
T8843 6345-6358 GO:0001750 denotes Outer segment
T8844 6359-6372 GO:0009653 denotes morphogenesis
T8845 6376-6379 PR:000005904 denotes Crx
T8846 6383-6397 CL:0000210 denotes photoreceptors
T8847 6408-6416 CHEBI:10545 denotes electron
T8848 6442-6456 CL:0000210 denotes photoreceptors
T8849 6473-6480 UBERON:0001773 denotes scleral
T8850 6495-6504 CHEBI:26130 denotes pigmented
T8851 6505-6515 UBERON:0000483 denotes epithelium
T8852 6548-6551 PR:000005904 denotes Crx
T8853 6573-6576 PR:000005904 denotes Crx
T8854 6606-6609 PR:000005904 denotes Crx
T8855 6613-6619 UBERON:0000966 denotes retina
T8856 6630-6646 GO:0032391 denotes connecting cilia
T8857 6651-6653 GO:0032391 denotes cc
T8858 6691-6705 GO:0001750 denotes outer segments
T8859 6720-6723 PR:000005904 denotes Crx
T8860 6727-6740 GO:0001750 denotes outer segment
T8861 6771-6785 GO:0001750 denotes outer segments
T8862 6819-6821 GO:0001750 denotes os
T8863 6847-6849 GO:0001750 denotes os
T8864 6855-6858 PR:000005904 denotes Crx
T8865 6862-6876 CL:0000210 denotes photoreceptors
T8866 6882-6898 GO:0032391 denotes connecting cilia
T8867 6938-6954 GO:0032391 denotes connecting cilia
T8868 7003-7016 GO:0001750 denotes outer segment
T8869 7044-7061 GO:0032391 denotes connecting cilium
T8870 7072-7074 GO:0032391 denotes cc
T8871 7108-7111 PR:000005904 denotes Crx
T8872 7165-7181 GO:0032391 denotes connecting cilia
T8873 7195-7198 PR:000005904 denotes Crx
T8874 7206-7208 GO:0032391 denotes cc
T9162 7253-7261 CHEBI:10545 denotes electron
T9163 7277-7280 PR:000005904 denotes Crx
T9164 7284-7298 CL:0000210 denotes photoreceptors
T9165 7306-7319 CL:0000210 denotes photoreceptor
T9166 7306-7325 UBERON:0001787 denotes photoreceptor layer
T9167 7337-7350 CL:0000210 denotes Photoreceptor
T9168 7337-7359 _FRAGMENT denotes Photoreceptor layer of
T9169 7367-7373 UBERON:0001787 denotes retina
T9170 7360-7363 PR:000005904 denotes Crx
T9171 7396-7409 GO:0001750 denotes outer segment
T9172 7443-7456 CL:0000210 denotes photoreceptor
T9173 7443-7473 GO:0032391 denotes photoreceptor connecting cilia
T9174 7475-7477 GO:0032391 denotes cc
T9175 7484-7487 PR:000005904 denotes Crx
T9176 7491-7505 CL:0000210 denotes photoreceptors
T9177 7516-7532 GO:0032391 denotes connecting cilia
T9178 7534-7536 GO:0032391 denotes cc
T9179 7576-7589 GO:0001750 denotes outer segment
T9294 8237-8245 CHEBI:10545 denotes electron
T9295 8282-8291 PR:000001245 denotes rhodopsin
T9296 8299-8313 CL:0000210 denotes photoreceptors
T9297 8338-8345 UBERON:0001773 denotes scleral
T9298 8360-8369 CHEBI:26130 denotes pigmented
T9299 8370-8380 UBERON:0000483 denotes epithelium
T9300 8390-8392 GO:0032391 denotes cc
T9301 8394-8411 GO:0032391 denotes connecting cilium
T9302 8413-8415 GO:0001917 denotes is
T9303 8417-8430 GO:0001917 denotes inner segment
T8224 1242-1256 GO:0001917 denotes inner segments
T8225 1258-1261 UBERON:0001789 denotes onl
T8226 1263-1282 UBERON:0001789 denotes outer nuclear layer
T8227 1269-1276 GO:0005634 denotes nuclear
T8228 1288-1301 CL:0000210 denotes photoreceptor
T8229 1302-1308 GO:0005634 denotes nuclei
T8214 1107-1115 CHEBI:10545 denotes electron
T8215 1140-1146 UBERON:0000966 denotes retina
T8216 1161-1164 PR:000005904 denotes Crx
T8217 1176-1179 PR:000005904 denotes Crx
T8218 1183-1190 UBERON:0000966 denotes retinas
T8219 1196-1205 CHEBI:26130 denotes pigmented
T8220 1206-1216 UBERON:0000483 denotes epithelium
T8221 1218-1220 GO:0001750 denotes os
T8222 1222-1236 GO:0001750 denotes outer segments
T8223 1238-1240 GO:0001917 denotes is
T8328 1363-1371 CHEBI:10545 denotes electron
T8329 1390-1403 GO:0001750 denotes outer segment
T8330 1390-1409 UBERON:0003926 denotes outer segment layer
T8331 1413-1416 PR:000005904 denotes Crx
T8332 1420-1426 UBERON:0000966 denotes retina
T8333 1435-1452 _FRAGMENT denotes Inner segments of
T8334 1460-1474 GO:0001917 denotes photoreceptors
T8335 1453-1456 PR:000005904 denotes Crx
T8336 1460-1474 CL:0000210 denotes photoreceptors
T8337 1492-1504 GO:0005739 denotes mitochondria
T8338 1506-1507 GO:0005739 denotes m
T8339 1534-1537 PR:000005904 denotes Crx
T8340 1558-1567 CHEBI:26130 denotes pigmented
T8341 1568-1578 UBERON:0000483 denotes epithelium
T8342 1580-1582 GO:0001917 denotes is
T2008 1648-1649 UBERON:0001789 denotes o
T2009 1649-1651 UBERON:0001789 denotes re
T2010 1650-1651 GO:0005634 denotes e
T2011 1651-1657 CL:0000210 denotes ceptor
T2012 1658-1659 GO:0005634 denotes i
T2013 1661-1663 CHEBI:10545 denotes er
T2014 1664-1671 GO:0001750 denotes segment
T2015 1664-1671 UBERON:0003926 denotes segment
T2016 1671-1673 _FRAGMENT denotes s
T2017 1673-1674 GO:0005739 denotes a
T2018 1679-1681 CHEBI:26130 denotes te
T2019 1681-1691 GO:0001917 denotes r segments
T2020 1692-1695 UBERON:0001789 denotes are
T2021 1692-1694 GO:0005634 denotes ar
T2022 1708-1736 GO:0032391 denotes non-motile connecting cilium
T2023 1789-1800 GO:0005874 denotes microtubule
T2024 1851-1854 PR:000005904 denotes Crx
T2025 1858-1865 UBERON:0000966 denotes retinas
T2026 1894-1910 GO:0032391 denotes connecting cilia
T2027 1956-1972 GO:0032391 denotes connecting cilia
T2028 2020-2031 GO:0005874 denotes microtubule
T2029 2073-2090 GO:0032391 denotes connecting cilium
T2030 2291-2304 GO:0001917 denotes inner segment
T2031 2316-2328 GO:0042384 denotes ciliogenesis
T2032 2355-2358 PR:000005904 denotes Crx
T2033 2362-2376 CL:0000210 denotes photoreceptors
T2034 2390-2393 PR:000005904 denotes Crx
T2035 2397-2404 UBERON:0000966 denotes retinas
T2036 2409-2437 UBERON:0001782 denotes retinal pigmented epithelium
T2037 2417-2426 CHEBI:26130 denotes pigmented
T2038 3698-3700 GO:0030263 denotes ti
T2039 3703-3704 GO:0031012 denotes t
T2040 3710-3711 GO:0031988 denotes c
T2041 3713-3714 CL:0000210 denotes p
T2042 3715-3716 GO:0005874 denotes e
T2043 3720-3723 GO:0031988 denotes bse
T2044 3724-3726 CL:0000210 denotes ce
T2045 3731-3744 GO:0001750 denotes uter segments
T2046 3746-3749 PR:000005904 denotes Crx
T2047 3753-3760 UBERON:0000966 denotes retinas
T2048 3810-3823 GO:0001750 denotes outer segment
T2049 3810-3829 UBERON:0003926 denotes outer segment layer
T2050 3864-3870 GO:0031012 denotes matrix
T2057 4279-4292 GO:0001750 denotes outer segment
T2058 4279-4298 UBERON:0003926 denotes outer segment layer
T2059 4319-4327 GO:0031982 denotes vesicles
T2060 4411-4425 GO:0001917 denotes inner segments
T2061 4439-4447 CHEBI:10545 denotes electron
T2062 4512-4526 GO:0001917 denotes inner segments
T2063 4584-4600 _FRAGMENT denotes morphogenesis of
T2064 4608-4622 GO:0008594 denotes photoreceptors
T2065 4601-4604 PR:000005904 denotes Crx
T2066 4608-4622 CL:0000210 denotes photoreceptors
T2067 4639-4652 GO:0001750 denotes outer segment
T2068 4639-4658 UBERON:0003926 denotes outer segment layer
T2069 4682-4690 CHEBI:10545 denotes electron
T2070 4736-4739 PR:000005904 denotes Crx
T2071 4743-4750 UBERON:0000966 denotes retinas
T2072 4752-4765 CL:0000210 denotes photoreceptor
T2073 4752-4780 GO:0001917 denotes photoreceptor inner segments
T2074 4782-4798 GO:0032391 denotes connecting cilia
T2075 4826-4839 GO:0001750 denotes outer segment
T2076 4876-4879 PR:000005904 denotes Crx
T2077 4883-4889 UBERON:0000966 denotes retina
T2078 4911-4928 GO:0032391 denotes connecting cilium
T2079 4953-4967 GO:0001917 denotes inner segments
T2080 5065-5073 CHEBI:10545 denotes electron
T2081 5159-5162 PR:000005904 denotes Crx
T2082 5170-5173 PR:000005904 denotes Crx
T2083 5177-5191 CL:0000210 denotes photoreceptors
T2084 5212-5226 GO:0001750 denotes outer segments
T2085 5241-5244 PR:000005904 denotes Crx
T2086 5248-5262 CL:0000210 denotes photoreceptors
T2087 5324-5328 GO:0045177 denotes apex
T2088 5349-5352 PR:000005904 denotes Crx
T2089 5356-5363 UBERON:0000966 denotes retinae
T2116 7679-7682 PR:000005904 denotes Crx
T2117 7686-7700 CL:0000210 denotes photoreceptors
T2118 7717-7726 PR:000001245 denotes rhodopsin
T2119 7748-7762 CL:0000210 denotes photoreceptors
T2120 7764-7773 PR:000001245 denotes Rhodopsin
T2121 7797-7810 CL:0000210 denotes photoreceptor
T2122 7820-7825 SO:0000704 denotes genes
T2123 7832-7842 GO:0010467 denotes expression
T2126 7952-7957 SO:0000704 denotes genes
R1142 T2064 T2063 _lexicallyChainedTo photoreceptors,morphogenesis of
R5116 T8334 T8333 _lexicallyChainedTo photoreceptors,Inner segments of
R5179 T8492 T8491 _lexicallyChainedTo retina,photoreceptor layer of
R5614 T9169 T9168 _lexicallyChainedTo retina,Photoreceptor layer of

craft-sa-dev

Id Subject Object Predicate Lexical cue
T2359 0-8 JJ denotes Multiple
T2360 9-20 NNS denotes pathologies
T2361 21-23 IN denotes in
T2362 24-27 DT denotes the
T2363 42-47 NN denotes layer
T2364 28-33 JJ denotes outer
T2365 34-41 NN denotes segment
T2366 48-50 IN denotes in
T2367 51-54 NN denotes Crx
T2368 58-62 NNS denotes mice
T2369 54-55 SYM denotes -
T2370 55-56 HYPH denotes /
T2371 56-57 SYM denotes -
T2372 62-179 sentence denotes A standard knock-out protocol was used to generate mice in which the homeodomain of Crx-/- was targeted and deleted.
T2373 63-64 DT denotes A
T2374 84-92 NN denotes protocol
T2375 65-73 JJ denotes standard
T2376 74-79 VB denotes knock
T2377 79-80 HYPH denotes -
T2378 80-83 RP denotes out
T2379 97-101 VBN denotes used
T2380 93-96 VBD denotes was
T2381 102-104 TO denotes to
T2382 105-113 VB denotes generate
T2383 114-118 NNS denotes mice
T2384 119-121 IN denotes in
T2385 158-166 VBN denotes targeted
T2386 122-127 WDT denotes which
T2387 128-131 DT denotes the
T2388 132-143 NN denotes homeodomain
T2389 144-146 IN denotes of
T2390 147-150 NN denotes Crx
T2391 150-151 SYM denotes -
T2392 151-152 HYPH denotes /
T2393 152-153 SYM denotes -
T2394 154-157 VBD denotes was
T2395 167-170 CC denotes and
T2396 171-178 VBN denotes deleted
T2397 178-179 . denotes .
T2398 179-245 sentence denotes Generation of these Crx-/- mice has been reported elsewhere [34].
T2399 180-190 NN denotes Generation
T2400 221-229 VBN denotes reported
T2401 191-193 IN denotes of
T2402 194-199 DT denotes these
T2403 207-211 NNS denotes mice
T2404 200-203 NN denotes Crx
T2405 203-204 SYM denotes -
T2406 204-205 HYPH denotes /
T2407 205-206 SYM denotes -
T2408 212-215 VBZ denotes has
T2409 216-220 VBN denotes been
T2410 230-239 RB denotes elsewhere
T2411 240-241 -LRB- denotes [
T2412 241-243 CD denotes 34
T2413 243-244 -RRB- denotes ]
T2414 244-245 . denotes .
T2415 245-430 sentence denotes In this study, in order to characterize further the role of Crx in photoreceptor morphogenesis, the outer retinae from Crx-/- mice were examined using transmission electron microscopy.
T2416 246-248 IN denotes In
T2417 382-390 VBN denotes examined
T2418 249-253 DT denotes this
T2419 254-259 NN denotes study
T2420 259-261 , denotes ,
T2421 261-263 IN denotes in
T2422 264-269 NN denotes order
T2423 270-272 TO denotes to
T2424 273-285 VB denotes characterize
T2425 286-293 RB denotes further
T2426 294-297 DT denotes the
T2427 298-302 NN denotes role
T2428 303-305 IN denotes of
T2429 306-309 NN denotes Crx
T2430 310-312 IN denotes in
T2431 313-326 NN denotes photoreceptor
T2432 327-340 NN denotes morphogenesis
T2433 340-342 , denotes ,
T2434 342-345 DT denotes the
T2435 352-359 NNS denotes retinae
T2436 346-351 JJ denotes outer
T2437 360-364 IN denotes from
T2438 365-368 NN denotes Crx
T2439 372-376 NNS denotes mice
T2440 368-369 SYM denotes -
T2441 369-370 HYPH denotes /
T2442 370-371 SYM denotes -
T2443 377-381 VBD denotes were
T2444 391-396 VBG denotes using
T2445 397-409 NN denotes transmission
T2446 419-429 NN denotes microscopy
T2447 410-418 NN denotes electron
T2448 429-430 . denotes .
T2449 430-609 sentence denotes At postnatal day 21 (P21), when Crx+/+ photoreceptors exhibited robust outer segments (Figure 1A, os), Crx-/- retinas were without a recognizable outer segment layer (Figure 1B).
T2450 431-433 IN denotes At
T2451 549-553 VBD denotes were
T2452 434-443 JJ denotes postnatal
T2453 444-447 NN denotes day
T2454 448-450 CD denotes 21
T2455 451-452 -LRB- denotes (
T2456 452-455 NN denotes P21
T2457 455-456 -RRB- denotes )
T2458 456-458 , denotes ,
T2459 458-462 WRB denotes when
T2460 485-494 VBD denotes exhibited
T2461 463-466 NN denotes Crx
T2462 470-484 NNS denotes photoreceptors
T2463 466-467 SYM denotes +
T2464 467-468 HYPH denotes /
T2465 468-469 SYM denotes +
T2466 495-501 JJ denotes robust
T2467 508-516 NNS denotes segments
T2468 502-507 JJ denotes outer
T2469 517-518 -LRB- denotes (
T2470 529-531 NN denotes os
T2471 518-524 NN denotes Figure
T2472 525-527 NN denotes 1A
T2473 527-529 , denotes ,
T2474 531-532 -RRB- denotes )
T2475 532-534 , denotes ,
T2476 534-537 NN denotes Crx
T2477 541-548 NNS denotes retinas
T2478 537-538 SYM denotes -
T2479 538-539 HYPH denotes /
T2480 539-540 SYM denotes -
T2481 554-561 IN denotes without
T2482 562-563 DT denotes a
T2483 591-596 NN denotes layer
T2484 564-576 JJ denotes recognizable
T2485 577-582 JJ denotes outer
T2486 583-590 NN denotes segment
T2487 597-598 -LRB- denotes (
T2488 598-604 NN denotes Figure
T2489 605-607 CD denotes 1B
T2490 607-608 -RRB- denotes )
T2491 608-609 . denotes .
T2492 609-784 sentence denotes Crx-/- photoreceptors had inner segments, demonstrating at least limited photoreceptor polarization in the Crx mutant, but the inner segments were extremely short (Figure 2).
T2493 610-613 NN denotes Crx
T2494 617-631 NNS denotes photoreceptors
T2495 613-614 SYM denotes -
T2496 614-615 HYPH denotes /
T2497 615-616 SYM denotes -
T2498 632-635 VBD denotes had
T2499 636-641 JJ denotes inner
T2500 642-650 NNS denotes segments
T2501 650-652 , denotes ,
T2502 652-665 VBG denotes demonstrating
T2503 666-668 RB denotes at
T2504 669-674 RBS denotes least
T2505 675-682 JJ denotes limited
T2506 697-709 NN denotes polarization
T2507 683-696 NN denotes photoreceptor
T2508 710-712 IN denotes in
T2509 713-716 DT denotes the
T2510 721-727 NN denotes mutant
T2511 717-720 NN denotes Crx
T2512 727-729 , denotes ,
T2513 729-732 CC denotes but
T2514 733-736 DT denotes the
T2515 743-751 NNS denotes segments
T2516 737-742 JJ denotes inner
T2517 752-756 VBD denotes were
T2518 757-766 RB denotes extremely
T2519 767-772 JJ denotes short
T2520 773-774 -LRB- denotes (
T2521 774-780 NN denotes Figure
T2522 781-782 CD denotes 2
T2523 782-783 -RRB- denotes )
T2524 783-784 . denotes .
T2525 784-946 sentence denotes Furthermore, the majority of inner segments showed some morphological differentiation, having approximately as many mitochondria as the control (Figure 1 and 2).
T2526 785-796 RB denotes Furthermore
T2527 829-835 VBD denotes showed
T2528 796-798 , denotes ,
T2529 798-801 DT denotes the
T2530 802-810 NN denotes majority
T2531 811-813 IN denotes of
T2532 814-819 JJ denotes inner
T2533 820-828 NNS denotes segments
T2534 836-840 DT denotes some
T2535 855-870 NN denotes differentiation
T2536 841-854 JJ denotes morphological
T2537 870-872 , denotes ,
T2538 872-878 VBG denotes having
T2539 879-892 RB denotes approximately
T2540 896-900 JJ denotes many
T2541 893-895 RB denotes as
T2542 901-913 NNS denotes mitochondria
T2543 914-916 IN denotes as
T2544 917-920 DT denotes the
T2545 921-928 NN denotes control
T2546 929-930 -LRB- denotes (
T2547 937-938 CD denotes 1
T2641 1848-1850 IN denotes in
T2642 1851-1854 NN denotes Crx
T2643 1858-1865 NNS denotes retinas
T2644 1854-1855 SYM denotes -
T2645 1855-1856 HYPH denotes /
T2646 1856-1857 SYM denotes -
T2647 1865-1867 , denotes ,
T2648 1867-1875 JJ denotes numerous
T2649 1882-1890 NNS denotes sections
T2650 1876-1881 NN denotes cross
T2651 1891-1893 IN denotes of
T2652 1894-1904 JJ denotes connecting
T2653 1905-1910 NNS denotes cilia
T2654 1911-1915 VBD denotes were
T2655 1922-1923 -LRB- denotes (
T2656 1930-1932 CD denotes 3A
T2657 1923-1929 NN denotes Figure
T2658 1933-1936 CC denotes and
T2659 1937-1939 CD denotes 3B
T2660 1939-1940 -RRB- denotes )
T2661 1940-1941 . denotes .
T2662 1941-2041 sentence denotes Sporadically, connecting cilia contained other than the typical complement of microtubule doublets.
T2663 1942-1954 RB denotes Sporadically
T2664 1973-1982 VBD denotes contained
T2665 1954-1956 , denotes ,
T2666 1956-1966 JJ denotes connecting
T2667 1967-1972 NNS denotes cilia
T2668 1983-1988 JJ denotes other
T2669 1989-1993 IN denotes than
T2670 1994-1997 DT denotes the
T2671 2006-2016 NN denotes complement
T2672 1998-2005 JJ denotes typical
T2673 2017-2019 IN denotes of
T2674 2020-2031 NN denotes microtubule
T2675 2032-2040 NNS denotes doublets
T2676 2040-2041 . denotes .
T2677 2041-2137 sentence denotes For example, in Figure 3A, the connecting cilium labelled by arrowhead 1, shows 7 + 0 doublets.
T2678 2042-2045 IN denotes For
T2679 2116-2121 VBZ denotes shows
T2680 2046-2053 NN denotes example
T2681 2053-2055 , denotes ,
T2682 2055-2057 IN denotes in
T2683 2058-2064 NN denotes Figure
T2684 2065-2067 NN denotes 3A
T2685 2067-2069 , denotes ,
T2686 2069-2072 DT denotes the
T2687 2084-2090 NN denotes cilium
T2688 2073-2083 JJ denotes connecting
T2689 2091-2099 VBN denotes labelled
T2690 2100-2102 IN denotes by
T2691 2103-2112 NN denotes arrowhead
T2692 2113-2114 CD denotes 1
T2693 2114-2116 , denotes ,
T2694 2122-2123 CD denotes 7
T2695 2126-2127 CD denotes 0
T2696 2124-2125 SYM denotes +
T2697 2128-2136 NNS denotes doublets
T2698 2136-2137 . denotes .
T2699 2137-2242 sentence denotes The majority exhibited the characteristic 9 + 0 doublets (arrowhead 2 and 3 in Figure 3A and Figure 3B).
T2700 2138-2141 DT denotes The
T2701 2142-2150 NN denotes majority
T2702 2151-2160 VBD denotes exhibited
T2703 2161-2164 DT denotes the
T2704 2186-2194 NNS denotes doublets
T2705 2165-2179 JJ denotes characteristic
T2706 2180-2181 CD denotes 9
T2707 2184-2185 CD denotes 0
T2708 2182-2183 SYM denotes +
T2709 2195-2196 -LRB- denotes (
T2710 2206-2207 CD denotes 2
T2711 2196-2205 NN denotes arrowhead
T2712 2208-2211 CC denotes and
T2713 2212-2213 CD denotes 3
T2714 2214-2216 IN denotes in
T2715 2217-2223 NN denotes Figure
T2716 2224-2226 NN denotes 3A
T2717 2227-2230 CC denotes and
T2718 2231-2237 NN denotes Figure
T2719 2238-2240 NN denotes 3B
T2720 2240-2241 -RRB- denotes )
T2721 2241-2242 . denotes .
T2722 2242-2377 sentence denotes These observations indicate that in addition to inner segment formation, ciliogenesis is also largely intact in Crx-/- photoreceptors.
T2723 2243-2248 DT denotes These
T2724 2249-2261 NNS denotes observations
T2725 2262-2270 VBP denotes indicate
T2726 2271-2275 IN denotes that
T2727 2329-2331 VBZ denotes is
T2728 2276-2278 IN denotes in
T2729 2279-2287 NN denotes addition
T2730 2288-2290 IN denotes to
T2731 2291-2296 JJ denotes inner
T2732 2297-2304 NN denotes segment
T2733 2305-2314 NN denotes formation
T2734 2314-2316 , denotes ,
T2735 2316-2328 NN denotes ciliogenesis
T2736 2332-2336 RB denotes also
T2737 2337-2344 RB denotes largely
T2738 2345-2351 JJ denotes intact
T2739 2352-2354 IN denotes in
T2740 2355-2358 NN denotes Crx
T2741 2362-2376 NNS denotes photoreceptors
T2742 2358-2359 SYM denotes -
T2743 2359-2360 HYPH denotes /
T2744 2360-2361 SYM denotes -
T2745 2376-2377 . denotes .
T2746 2377-2521 sentence denotes Further, in Crx-/- retinas the retinal pigmented epithelium (PE) appeared normal, at least up to P21 (data not shown), the oldest age examined.
T2836 3831-3836 RB denotes First
T2837 3895-3900 VBN denotes noted
T2838 3836-3838 , denotes ,
T2839 3838-3840 DT denotes an
T2840 3850-3860 NN denotes deposition
T2841 3841-3849 JJ denotes abnormal
T2842 3861-3863 IN denotes of
T2843 3864-3870 NN denotes matrix
T2844 3871-3873 IN denotes of
T2845 3874-3881 JJ denotes unknown
T2846 3882-3890 NN denotes identity
T2847 3891-3894 VBD denotes was
T2848 3901-3902 -LRB- denotes (
T2849 3913-3915 NN denotes mx
T2850 3902-3908 NN denotes Figure
T2851 3909-3911 NN denotes 3A
T2852 3911-3913 , denotes ,
T2853 3915-3916 -RRB- denotes )
T2854 3916-3917 . denotes .
T2855 3917-4005 sentence denotes Second, sporadically displaced nuclei were found residing in the space abutting the PE.
T2856 3918-3924 RB denotes Second
T2857 3961-3966 VBN denotes found
T2858 3924-3926 , denotes ,
T2859 3926-3938 RB denotes sporadically
T2860 3939-3948 VBN denotes displaced
T2861 3949-3955 NNS denotes nuclei
T2862 3956-3960 VBD denotes were
T2863 3967-3975 VBG denotes residing
T2864 3976-3978 IN denotes in
T2865 3979-3982 DT denotes the
T2866 3983-3988 NN denotes space
T2867 3989-3997 VBG denotes abutting
T2868 3998-4001 DT denotes the
T2869 4002-4004 NN denotes PE
T2870 4004-4005 . denotes .
T2871 4005-4235 sentence denotes Occasionally, these nuclei appeared pyknotic (Figure 3A, n); but, more frequently exhibited the heterochromatin pattern typical of photoreceptors (data not shown), strongly suggesting that they belonged to ectopic photoreceptors.
T2872 4006-4018 RB denotes Occasionally
T2873 4033-4041 VBD denotes appeared
T2874 4018-4020 , denotes ,
T2875 4020-4025 DT denotes these
T2876 4026-4032 NNS denotes nuclei
T2877 4042-4050 JJ denotes pyknotic
T2878 4051-4052 -LRB- denotes (
T2879 4063-4064 NN denotes n
T2880 4052-4058 NN denotes Figure
T2881 4059-4061 NN denotes 3A
T2882 4061-4063 , denotes ,
T2883 4064-4065 -RRB- denotes )
T2884 4065-4066 : denotes ;
T2885 4067-4070 CC denotes but
T2886 4070-4072 , denotes ,
T2887 4072-4076 RBR denotes more
T2888 4077-4087 RB denotes frequently
T2889 4088-4097 VBD denotes exhibited
T2890 4098-4101 DT denotes the
T2891 4118-4125 NN denotes pattern
T2892 4102-4117 NN denotes heterochromatin
T2893 4126-4133 JJ denotes typical
T2894 4134-4136 IN denotes of
T2895 4137-4151 NNS denotes photoreceptors
T2896 4152-4153 -LRB- denotes (
T2897 4162-4167 VBN denotes shown
T2898 4153-4157 NNS denotes data
T2899 4158-4161 RB denotes not
T2900 4167-4168 -RRB- denotes )
T2901 4168-4170 , denotes ,
T2902 4170-4178 RB denotes strongly
T2903 4179-4189 VBG denotes suggesting
T2904 4190-4194 IN denotes that
T2905 4200-4208 VBD denotes belonged
T2906 4195-4199 PRP denotes they
T2907 4209-4211 IN denotes to
T2908 4212-4219 JJ denotes ectopic
T2909 4220-4234 NNS denotes photoreceptors
T2910 4234-4235 . denotes .
T2911 4235-4372 sentence denotes The third pathological entity noted in the outer segment layer were numerous small vesicles (Figure 3A arrow) 100 to 200 nm in diameter.
T2912 4236-4239 DT denotes The
T2913 4259-4265 NN denotes entity
T2914 4240-4245 JJ denotes third
T2915 4246-4258 JJ denotes pathological
T2916 4299-4303 VBD denotes were
T2917 4266-4271 VBN denotes noted
T2918 4272-4274 IN denotes in
T2919 4275-4278 DT denotes the
T2920 4293-4298 NN denotes layer
T2921 4279-4284 JJ denotes outer
T2922 4285-4292 NN denotes segment
T2923 4304-4312 JJ denotes numerous
T2924 4319-4327 NNS denotes vesicles
T2925 4313-4318 JJ denotes small
T2926 4328-4329 -LRB- denotes (
T2927 4339-4344 NN denotes arrow
T2928 4329-4335 NN denotes Figure
T2929 4336-4338 NN denotes 3A
T2930 4344-4345 -RRB- denotes )
T2931 4346-4349 CD denotes 100
T2932 4353-4356 CD denotes 200
T2933 4350-4352 IN denotes to
T2934 4357-4359 NN denotes nm
T2935 4360-4362 IN denotes in
T2936 4363-4371 NN denotes diameter
T2937 4371-4372 . denotes .
T2938 4372-4546 sentence denotes They appeared to be emerging from the inner segments, as scanning electron microscopic images showed spherical structures budding from the inner segments (Figure 3C, arrow).
T2939 4373-4377 PRP denotes They
T2940 4378-4386 VBD denotes appeared
T2941 4387-4389 TO denotes to
T2942 4393-4401 VBG denotes emerging
T2943 4390-4392 VB denotes be
T2944 4402-4406 IN denotes from
T2945 4407-4410 DT denotes the
T2946 4417-4425 NNS denotes segments
T2947 4411-4416 JJ denotes inner
T2948 4425-4427 , denotes ,
T2949 4427-4429 IN denotes as
T2950 4467-4473 VBD denotes showed
T2951 4430-4438 VBG denotes scanning
T2952 4439-4447 NN denotes electron
T2953 4448-4459 JJ denotes microscopic
T2954 4460-4466 NNS denotes images
T2955 4474-4483 JJ denotes spherical
T2956 4484-4494 NNS denotes structures
T2957 4495-4502 VBG denotes budding
T2958 4503-4507 IN denotes from
T2959 4508-4511 DT denotes the
T2960 4518-4526 NNS denotes segments
T2961 4512-4517 JJ denotes inner
T2962 4527-4528 -LRB- denotes (
T2963 4539-4544 NN denotes arrow
T2964 4528-4534 NN denotes Figure
T2965 4535-4537 NN denotes 3C
T2966 4537-4539 , denotes ,
T2967 4544-4545 -RRB- denotes )
T2968 4545-4546 . denotes .
T2969 4546-4732 sentence denotes In order to characterize further the morphogenesis of Crx-/- photoreceptors, the developing outer segment layer was viewed by scanning electron microscopy at P7, P14 and P21 (Figure 4).
T2970 4547-4549 IN denotes In
T2971 4663-4669 VBN denotes viewed
T2972 4550-4555 NN denotes order
T2973 4556-4558 TO denotes to
T2974 4559-4571 VB denotes characterize
T2975 4572-4579 RB denotes further
T2976 4580-4583 DT denotes the
T2977 4584-4597 NN denotes morphogenesis
T2978 4598-4600 IN denotes of
T2979 4601-4604 NN denotes Crx
T2980 4608-4622 NNS denotes photoreceptors
T2981 4604-4605 SYM denotes -
T2982 4605-4606 HYPH denotes /
T2983 4606-4607 SYM denotes -
T2984 4622-4624 , denotes ,
T2985 4624-4627 DT denotes the
T2986 4653-4658 NN denotes layer
T2987 4628-4638 VBG denotes developing
T2988 4639-4644 JJ denotes outer
T2989 4645-4652 NN denotes segment
T2990 4659-4662 VBD denotes was
T2991 4670-4672 IN denotes by
T2992 4673-4681 VBG denotes scanning
T2993 4691-4701 NN denotes microscopy
T2994 4682-4690 NN denotes electron
T2995 4702-4704 IN denotes at
T2996 4705-4707 NN denotes P7
T2997 4707-4709 , denotes ,
T2998 4709-4712 NN denotes P14
T2999 4713-4716 CC denotes and
T3000 4717-4720 NN denotes P21
T3001 4721-4722 -LRB- denotes (
T3002 4722-4728 NN denotes Figure
T3003 4729-4730 CD denotes 4
T3004 4730-4731 -RRB- denotes )
T3005 4731-4732 . denotes .
T3006 4732-4868 sentence denotes In Crx+/+ retinas, photoreceptor inner segments, connecting cilia, and the first rudimentary outer segment structures were noted at P7.
T3007 4733-4735 IN denotes In
T3008 4856-4861 VBN denotes noted
T3009 4736-4739 NN denotes Crx
T3010 4743-4750 NNS denotes retinas
T3011 4739-4740 SYM denotes +
T3012 4740-4741 HYPH denotes /
T3013 4741-4742 SYM denotes +
T3014 4750-4752 , denotes ,
T3015 4752-4765 NN denotes photoreceptor
T3016 4772-4780 NNS denotes segments
T3017 4766-4771 JJ denotes inner
T3018 4780-4782 , denotes ,
T3019 4782-4792 VBG denotes connecting
T3020 4793-4798 NNS denotes cilia
T3021 4798-4800 , denotes ,
T3022 4800-4803 CC denotes and
T3023 4804-4807 DT denotes the
T3024 4840-4850 NNS denotes structures
T3025 4808-4813 JJ denotes first
T3026 4814-4825 JJ denotes rudimentary
T3027 4826-4831 JJ denotes outer
T3028 4832-4839 NN denotes segment
T3029 4851-4855 VBD denotes were
T3030 4862-4864 IN denotes at
T3031 4865-4867 NN denotes P7
T3032 4867-4868 . denotes .
T3033 4868-5001 sentence denotes In the Crx-/- retina, only an occassional connecting cilium was noted emerging from inner segments at this stage (Figure 4A and 4B).
T3034 4869-4871 IN denotes In
T3035 4939-4947 VBG denotes emerging
T3036 4872-4875 DT denotes the
T3037 4883-4889 NN denotes retina
T3038 4876-4879 NN denotes Crx
T3039 4879-4880 SYM denotes -
T3040 4880-4881 HYPH denotes /
T3041 4881-4882 SYM denotes -
T3042 4889-4891 , denotes ,
T3043 4891-4895 RB denotes only
T3044 4922-4928 NN denotes cilium
T3045 4896-4898 DT denotes an
T3046 4899-4910 JJ denotes occassional
T3047 4911-4921 VBG denotes connecting
T3048 4929-4932 VBD denotes was
T3049 4933-4938 VBN denotes noted
T3050 4948-4952 IN denotes from
T3051 4953-4958 JJ denotes inner
T3052 4959-4967 NNS denotes segments
T3053 4968-4970 IN denotes at
T3054 4971-4975 DT denotes this
T3055 4976-4981 NN denotes stage
T3056 4982-4983 -LRB- denotes (
T3057 4990-4992 NN denotes 4A
T3058 4983-4989 NN denotes Figure
T3059 4993-4996 CC denotes and
T3060 4997-4999 NN denotes 4B
T3061 4999-5000 -RRB- denotes )
T3062 5000-5001 . denotes .
T3063 5001-5097 sentence denotes This observation was confirmed by comparison with transmission electron micrographs (Figure 5).
T3064 5002-5006 DT denotes This
T3065 5007-5018 NN denotes observation
T3066 5023-5032 VBN denotes confirmed
T3067 5019-5022 VBD denotes was
T3068 5033-5035 IN denotes by
T3069 5036-5046 NN denotes comparison
T3070 5047-5051 IN denotes with
T3071 5052-5064 NN denotes transmission
T3072 5074-5085 NNS denotes micrographs
T3073 5065-5073 NN denotes electron
T3074 5086-5087 -LRB- denotes (
T3075 5087-5093 NN denotes Figure
T3076 5094-5095 CD denotes 5
T3077 5095-5096 -RRB- denotes )
T3078 5096-5097 . denotes .
T3079 5097-5192 sentence denotes These differences are the earliest noted differences between Crx+/+ and Crx-/- photoreceptors.
T3080 5098-5103 DT denotes These
T3081 5104-5115 NNS denotes differences
T3082 5116-5119 VBP denotes are
T3083 5120-5123 DT denotes the
T3084 5139-5150 NNS denotes differences
T3085 5124-5132 JJS denotes earliest
T3086 5133-5138 VBN denotes noted
T3087 5151-5158 IN denotes between
T3088 5159-5162 NN denotes Crx
T3089 5177-5191 NNS denotes photoreceptors
T3090 5162-5163 SYM denotes +
T3091 5163-5164 HYPH denotes /
T3092 5164-5165 SYM denotes +
T3093 5166-5169 CC denotes and
T3094 5170-5173 NN denotes Crx
T3095 5173-5174 SYM denotes -
T3096 5174-5175 HYPH denotes /
T3097 5175-5176 SYM denotes -
T3098 5191-5192 . denotes .
T3099 5192-5345 sentence denotes At P14, elongating outer segments were noted on Crx+/+ photoreceptors, occasionally demonstrating a paddle-like structure at their apex (Figure 4C, os).
T3100 5193-5195 IN denotes At
T3101 5232-5237 VBN denotes noted
T3102 5196-5199 NN denotes P14
T3103 5199-5201 , denotes ,
T3104 5201-5211 VBG denotes elongating
T3105 5218-5226 NNS denotes segments
T3106 5212-5217 JJ denotes outer
T3107 5227-5231 VBD denotes were
T3108 5238-5240 IN denotes on
T3109 5241-5244 NN denotes Crx
T3110 5248-5262 NNS denotes photoreceptors
T3111 5244-5245 SYM denotes +
T3112 5245-5246 HYPH denotes /
T3113 5246-5247 SYM denotes +
T3114 5262-5264 , denotes ,
T3115 5264-5276 RB denotes occasionally
T3116 5277-5290 VBG denotes demonstrating
T3117 5291-5292 DT denotes a
T3118 5305-5314 NN denotes structure
T3119 5293-5299 NN denotes paddle
T3120 5300-5304 JJ denotes like
T3121 5299-5300 HYPH denotes -
T3122 5315-5317 IN denotes at
T3123 5318-5323 PRP$ denotes their
T3124 5324-5328 NN denotes apex
T3125 5329-5330 -LRB- denotes (
T3126 5341-5343 NN denotes os
T3127 5330-5336 NN denotes Figure
T3128 5337-5339 NN denotes 4C
T3129 5339-5341 , denotes ,
T3130 5343-5344 -RRB- denotes )
T3131 5344-5345 . denotes .
T3132 5345-5484 sentence denotes In Crx-/- retinae, the vast majority of photoreceptors at this stage demonstrated connecting cilia without outer segments (Figure 4D, cc).
T3133 5346-5348 IN denotes In
T3134 5415-5427 VBD denotes demonstrated
T3135 5349-5352 NN denotes Crx
T3136 5356-5363 NNS denotes retinae
T3137 5352-5353 SYM denotes -
T3138 5353-5354 HYPH denotes /
T3139 5354-5355 SYM denotes -
T3140 5363-5365 , denotes ,
T3141 5365-5368 DT denotes the
T3142 5374-5382 NN denotes majority
T3143 5369-5373 JJ denotes vast
T3144 5383-5385 IN denotes of
T3145 5386-5400 NNS denotes photoreceptors
T3146 5401-5403 IN denotes at
T3147 5404-5408 DT denotes this
T3148 5409-5414 NN denotes stage
T3149 5428-5438 VBG denotes connecting
T3150 5439-5444 NNS denotes cilia
T3151 5445-5452 IN denotes without
T3152 5453-5458 JJ denotes outer
T3153 5459-5467 NNS denotes segments
T3154 5468-5469 -LRB- denotes (
T3155 5480-5482 NN denotes cc
T3156 5469-5475 NN denotes Figure
T3157 5476-5478 NN denotes 4D
T3158 5478-5480 , denotes ,
T3159 5482-5483 -RRB- denotes )
T3160 5483-5484 . denotes .
T3161 5484-5657 sentence denotes Sporadically, Crx-/- photoreceptors would exhibit an irregular structure extending from a connecting cilium (Figure 4D, cc*) perhaps representing a malformed outer segment.
T3162 5485-5497 RB denotes Sporadically
T3163 5527-5534 VB denotes exhibit
T3164 5497-5499 , denotes ,
T3165 5499-5502 NN denotes Crx
T3166 5506-5520 NNS denotes photoreceptors
T3167 5502-5503 SYM denotes -
T3168 5503-5504 HYPH denotes /
T3169 5504-5505 SYM denotes -
T3170 5521-5526 MD denotes would
T3171 5535-5537 DT denotes an
T3172 5548-5557 NN denotes structure
T3173 5538-5547 JJ denotes irregular
T3174 5558-5567 VBG denotes extending
T3175 5568-5572 IN denotes from
T3176 5573-5574 DT denotes a
T3177 5586-5592 NN denotes cilium
T3178 5575-5585 VBG denotes connecting
T3179 5593-5594 -LRB- denotes (
T3180 5605-5608 NN denotes cc*
T3181 5594-5600 NN denotes Figure
T3182 5601-5603 NN denotes 4D
T3183 5603-5605 , denotes ,
T3184 5608-5609 -RRB- denotes )
T3185 5610-5617 RB denotes perhaps
T3186 5618-5630 VBG denotes representing
T3187 5631-5632 DT denotes a
T3188 5649-5656 NN denotes segment
T3189 5633-5642 JJ denotes malformed
T3190 5643-5648 JJ denotes outer
T3191 5656-5657 . denotes .
T3192 5657-5717 sentence denotes Such structures were also observed at P21 (Figure 4F, cc*).
T3193 5658-5662 JJ denotes Such
T3194 5663-5673 NNS denotes structures
T3195 5684-5692 VBN denotes observed
T3196 5674-5678 VBD denotes were
T3197 5679-5683 RB denotes also
T3198 5693-5695 IN denotes at
T3199 5696-5699 NN denotes P21
T3200 5700-5701 -LRB- denotes (
T3201 5712-5715 NN denotes cc*
T3202 5701-5707 NN denotes Figure
T3203 5708-5710 NN denotes 4F
T3204 5710-5712 , denotes ,
T3205 5715-5716 -RRB- denotes )
T3206 5716-5717 . denotes .
T3207 5717-5840 sentence denotes These putative, abnormal outer segments were only rarely noted in Crx+/+ at P14, and never at P21 (Figure 4C and 4E, cc*).
T3208 5718-5723 DT denotes These
T3209 5749-5757 NNS denotes segments
T3210 5724-5732 JJ denotes putative
T3211 5732-5734 , denotes ,
T3212 5734-5742 JJ denotes abnormal
T3213 5743-5748 JJ denotes outer
T3214 5775-5780 VBN denotes noted
T3215 5758-5762 VBD denotes were
T3216 5763-5767 RB denotes only
T3217 5768-5774 RB denotes rarely
T3218 5781-5783 IN denotes in
T3219 5784-5787 NN denotes Crx
T3220 5787-5788 SYM denotes +
T3221 5788-5789 HYPH denotes /
T3222 5789-5790 SYM denotes +
T3223 5791-5793 IN denotes at
T3224 5794-5797 NN denotes P14
T3225 5797-5799 , denotes ,
T3226 5799-5802 CC denotes and
T3227 5803-5808 RB denotes never
T3228 5809-5811 IN denotes at
T3229 5812-5815 NN denotes P21
T3230 5816-5817 -LRB- denotes (
T3231 5835-5837 NN denotes cc
T3232 5817-5823 NN denotes Figure
T3233 5824-5826 NN denotes 4C
T3234 5827-5830 CC denotes and
T3235 5831-5833 NN denotes 4E
T3236 5833-5835 , denotes ,
T3237 5837-5838 SYM denotes *
T3238 5838-5839 -RRB- denotes )
T3239 5839-5840 . denotes .
T3240 5840-5935 sentence denotes Further, in Crx-/- photoreceptors, unusually long connecting cilia were noted (Figure 4F, cc).
T3241 5841-5848 RB denotes Further
T3242 5913-5918 VBN denotes noted
T3243 5848-5850 , denotes ,
T3244 5850-5852 IN denotes in
T3245 5853-5856 NN denotes Crx
T3246 5860-5874 NNS denotes photoreceptors
T3247 5856-5857 SYM denotes -
T3248 5857-5858 HYPH denotes /
T3249 5858-5859 SYM denotes -
T3250 5874-5876 , denotes ,
T3251 5876-5885 RB denotes unusually
T3252 5886-5890 JJ denotes long
T3253 5902-5907 NNS denotes cilia
T3254 5891-5901 VBG denotes connecting
T3255 5908-5912 VBD denotes were
T3256 5919-5920 -LRB- denotes (
T3257 5931-5933 NN denotes cc
T3276 5987-5990 NN denotes P10
T3277 5990-5992 , denotes ,
T3278 5992-5995 NN denotes P14
T3279 5995-5997 , denotes ,
T3280 5997-6000 CC denotes and
T3281 6001-6004 NN denotes P21
T3282 6005-6007 IN denotes by
T3283 6008-6011 NN denotes TEM
T3284 6011-6013 , denotes ,
T3285 6026-6027 DT denotes a
T3286 6040-6044 NN denotes lack
T3287 6028-6039 JJ denotes distinctive
T3288 6045-6047 IN denotes of
T3289 6048-6051 DT denotes any
T3290 6052-6061 NN denotes structure
T3291 6062-6075 JJ denotes interpretable
T3292 6076-6078 IN denotes as
T3293 6079-6086 JJ denotes orderly
T3294 6087-6093 NNS denotes stacks
T3295 6094-6096 IN denotes of
T3296 6097-6102 NNS denotes discs
T3297 6103-6105 CC denotes or
T3298 6106-6113 VBG denotes forming
T3299 6114-6119 NNS denotes discs
T3300 6119-6120 . denotes .
T3301 6120-6334 sentence denotes These data demonstrate a complete absence of normal outer segment formation in the Crx mutant mouse, and the arrest of development of the photoreceptor appendage at the elongation stage of outer segment formation.
T3302 6121-6126 DT denotes These
T3303 6127-6131 NNS denotes data
T3304 6132-6143 VBP denotes demonstrate
T3305 6144-6145 DT denotes a
T3306 6155-6162 NN denotes absence
T3307 6146-6154 JJ denotes complete
T3308 6163-6165 IN denotes of
T3309 6166-6172 JJ denotes normal
T3310 6187-6196 NN denotes formation
T3311 6173-6178 JJ denotes outer
T3312 6179-6186 NN denotes segment
T3313 6197-6199 IN denotes in
T3314 6200-6203 DT denotes the
T3315 6215-6220 NN denotes mouse
T3316 6204-6207 NN denotes Crx
T3317 6208-6214 NN denotes mutant
T3318 6220-6222 , denotes ,
T3319 6222-6225 CC denotes and
T3320 6226-6229 DT denotes the
T3321 6230-6236 NN denotes arrest
T3322 6237-6239 IN denotes of
T3323 6240-6251 NN denotes development
T3324 6252-6254 IN denotes of
T3325 6255-6258 DT denotes the
T3326 6273-6282 NN denotes appendage
T3327 6259-6272 NN denotes photoreceptor
T3328 6283-6285 IN denotes at
T3329 6286-6289 DT denotes the
T3330 6301-6306 NN denotes stage
T3331 6290-6300 NN denotes elongation
T3332 6307-6309 IN denotes of
T3333 6310-6315 JJ denotes outer
T3334 6316-6323 NN denotes segment
T3335 6324-6333 NN denotes formation
T3336 6333-6334 . denotes .
T3337 6334-6337 sentence denotes Fi
T3338 6335-6337 NN denotes Fi
T3339 7640-7641 sentence denotes n
T3340 7640-7641 NN denotes n
T3341 7641-7644 sentence denotes all
T3342 7641-7642 VBG denotes a
T3343 7642-7643 NN denotes l
T3344 7643-7644 VBG denotes l
T3388 7764-7773 NN denotes Rhodopsin
T3389 7789-7792 VBP denotes are
T3390 7774-7777 CC denotes and
T3391 7778-7788 NN denotes peripherin
T3392 7793-7796 CD denotes two
T3393 7820-7825 NNS denotes genes
T3394 7797-7810 NN denotes photoreceptor
T3395 7811-7819 JJ denotes specific
T3396 7810-7811 HYPH denotes -
T3397 7826-7831 WP$ denotes whose
T3398 7832-7842 NN denotes expression
T3399 7860-7873 VBN denotes downregulated
T3400 7843-7845 VBZ denotes is
T3401 7846-7859 RB denotes significantly
T3402 7874-7876 IN denotes in
T3403 7877-7880 DT denotes the
T3404 7888-7895 NNS denotes retinae
T3405 7881-7884 NN denotes Crx
T3406 7884-7885 SYM denotes -
T3407 7885-7886 HYPH denotes /
T3408 7886-7887 SYM denotes -
T3409 7896-7897 -LRB- denotes [
T3410 7903-7905 CD denotes 35
T3411 7897-7899 CD denotes 10
T3412 7899-7900 , denotes ,
T3413 7900-7902 CD denotes 34
T3414 7902-7903 , denotes ,
T3415 7905-7906 -RRB- denotes ]
T3416 7906-7907 . denotes .
T3417 7907-8047 sentence denotes Loss of function mutations in each of these genes separately have been reported to result in a failure to elaborate outer segments [29,30].
T3418 7908-7912 NN denotes Loss
T3419 7925-7934 NNS denotes mutations
T3420 7913-7915 IN denotes of
T3421 7916-7924 NN denotes function
T3422 7979-7987 VBN denotes reported
T3423 7935-7937 IN denotes in
T3424 7938-7942 DT denotes each
T3425 7943-7945 IN denotes of
T3426 7946-7951 DT denotes these
T3427 7952-7957 NNS denotes genes
T3428 7958-7968 RB denotes separately
T3429 7969-7973 VBP denotes have
T3430 7974-7978 VBN denotes been
T3431 7988-7990 TO denotes to
T3432 7991-7997 VB denotes result
T3433 7998-8000 IN denotes in
T3434 8001-8002 DT denotes a
T3435 8003-8010 NN denotes failure
T3436 8011-8013 TO denotes to
T3437 8014-8023 VB denotes elaborate
T3438 8024-8029 JJ denotes outer
T3439 8030-8038 NNS denotes segments
T3440 8039-8040 -LRB- denotes [
T3441 8043-8045 CD denotes 30
T3442 8040-8042 CD denotes 29
T3443 8042-8043 , denotes ,
T3444 8045-8046 -RRB- denotes ]
T3445 8046-8047 . denotes .
T3446 8047-8217 sentence denotes Photoreceptors from these two mutant mice examined by SEM from the scleral side appeared highly similar to Crx-/- photoreceptors (compare Figure 4F to Figure 6A and 6B).
T3447 8048-8062 NNS denotes Photoreceptors
T3448 8128-8136 VBD denotes appeared
T3449 8063-8067 IN denotes from
T3450 8068-8073 DT denotes these
T3451 8085-8089 NNS denotes mice
T3452 8074-8077 CD denotes two
T3453 8078-8084 JJ denotes mutant
T3454 8090-8098 VBN denotes examined
T3455 8099-8101 IN denotes by
T3456 8102-8105 NN denotes SEM
T3457 8106-8110 IN denotes from
T3458 8111-8114 DT denotes the
T3459 8123-8127 NN denotes side
T3460 8115-8122 JJ denotes scleral
T3461 8137-8143 RB denotes highly
T3462 8144-8151 JJ denotes similar
T3463 8152-8154 IN denotes to
T3464 8155-8158 NN denotes Crx
T3465 8162-8176 NNS denotes photoreceptors
T3466 8158-8159 SYM denotes -
T3467 8159-8160 HYPH denotes /
T3468 8160-8161 SYM denotes -
T3469 8177-8178 -LRB- denotes (
T3470 8178-8185 VB denotes compare
T3471 8186-8192 NN denotes Figure
T3472 8193-8195 NN denotes 4F
T3473 8196-8198 IN denotes to
T3474 8199-8205 NN denotes Figure
T3475 8206-8208 NN denotes 6A
T3476 8209-8212 CC denotes and
T3477 8213-8215 NN denotes 6B
T3478 8215-8216 -RRB- denotes )
T3479 8216-8217 . denotes .
T8250 1094-1106 NN denotes Transmission
T8251 1116-1126 NN denotes microscopy
T8252 1107-1115 NN denotes electron
T8253 1127-1129 IN denotes of
T8254 1130-1133 DT denotes the
T8255 1140-1146 NN denotes retina
T8256 1134-1139 JJ denotes outer
T8257 1147-1149 IN denotes at
T8258 1150-1153 NN denotes P21
T8259 1154-1156 IN denotes in
T8260 1157-1158 -LRB- denotes (
T8261 1158-1159 LS denotes A
T8262 1161-1164 NN denotes Crx
T8263 1159-1160 -RRB- denotes )
T8264 1183-1190 NNS denotes retinas
T8265 1164-1165 SYM denotes +
T8266 1165-1166 HYPH denotes /
T8267 1166-1167 SYM denotes +
T8268 1168-1171 CC denotes and
T8269 1172-1173 -LRB- denotes (
T8270 1173-1174 LS denotes B
T8271 1176-1179 NN denotes Crx
T8272 1174-1175 -RRB- denotes )
T8273 1179-1180 SYM denotes -
T8274 1180-1181 HYPH denotes /
T8275 1181-1182 SYM denotes -
T8276 1190-1191 . denotes .
T8277 1191-1217 sentence denotes pe, pigmented epithelium.
T8278 1192-1194 NN denotes pe
T8279 1194-1196 , denotes ,
T8280 1196-1205 JJ denotes pigmented
T8281 1206-1216 NN denotes epithelium
T8282 1216-1217 . denotes .
T8283 1217-1237 sentence denotes os, outer segments.
T8284 1218-1220 NN denotes os
T8285 1220-1222 , denotes ,
T8286 1222-1227 JJ denotes outer
T8287 1228-1236 NNS denotes segments
T8288 1236-1237 . denotes .
T8289 1237-1257 sentence denotes is, inner segments.
T8290 1238-1240 NN denotes is
T8291 1240-1242 , denotes ,
T8292 1242-1247 JJ denotes inner
T8293 1248-1256 NNS denotes segments
T8294 1256-1257 . denotes .
T8295 1257-1309 sentence denotes onl, outer nuclear layer with photoreceptor nuclei.
T8296 1258-1261 NN denotes onl
T8297 1261-1263 , denotes ,
T8298 1263-1268 JJ denotes outer
T8299 1277-1282 NN denotes layer
T8300 1269-1276 JJ denotes nuclear
T8301 1283-1287 IN denotes with
T8302 1288-1301 NN denotes photoreceptor
T8303 1302-1308 NNS denotes nuclei
T8304 1308-1309 . denotes .
T8305 1309-1339 sentence denotes Scale bar = 5 μm for A and B.
T8306 1310-1315 NN denotes Scale
T8307 1316-1319 NN denotes bar
T8308 1324-1326 NN denotes μm
T8309 1320-1321 SYM denotes =
T8310 1322-1323 CD denotes 5
T8311 1327-1330 IN denotes for
T8312 1331-1332 NN denotes A
T8313 1333-1336 CC denotes and
T8314 1337-1338 NN denotes B
T8315 1338-1339 . denotes .
T8372 1350-1362 NN denotes Transmission
T8373 1372-1382 NN denotes micrograph
T8374 1363-1371 NN denotes electron
T8375 1383-1385 IN denotes of
T8376 1386-1389 DT denotes the
T8377 1404-1409 NN denotes layer
T8378 1390-1395 JJ denotes outer
T8379 1396-1403 NN denotes segment
T8380 1410-1412 IN denotes of
T8381 1413-1416 NN denotes Crx
T8382 1420-1426 NN denotes retina
T8383 1416-1417 SYM denotes -
T8384 1417-1418 HYPH denotes /
T8385 1418-1419 SYM denotes -
T8386 1427-1429 IN denotes at
T8387 1430-1433 NN denotes P21
T8388 1433-1434 . denotes .
T8389 1434-1553 sentence denotes Inner segments of Crx-/- photoreceptors exhibit numerous mitochondria (m indicated by arrow) as in Crx+/+ (Figure 1A).
T8390 1435-1440 JJ denotes Inner
T8391 1441-1449 NNS denotes segments
T8392 1475-1482 VBP denotes exhibit
T8393 1450-1452 IN denotes of
T8394 1453-1456 NN denotes Crx
T8395 1460-1474 NNS denotes photoreceptors
T8396 1456-1457 SYM denotes -
T8397 1457-1458 HYPH denotes /
T8398 1458-1459 SYM denotes -
T8399 1483-1491 JJ denotes numerous
T8400 1492-1504 NNS denotes mitochondria
T8401 1505-1506 -LRB- denotes (
T8402 1508-1517 VBN denotes indicated
T8403 1506-1507 NN denotes m
T8404 1518-1520 IN denotes by
T8405 1521-1526 NN denotes arrow
T8406 1526-1527 -RRB- denotes )
T8407 1528-1530 IN denotes as
T8408 1531-1533 IN denotes in
T8409 1534-1537 NN denotes Crx
T8410 1537-1538 SYM denotes +
T8411 1538-1539 HYPH denotes /
T8412 1539-1540 SYM denotes +
T8413 1541-1542 -LRB- denotes (
T8414 1542-1548 NN denotes Figure
T8415 1549-1551 CD denotes 1A
T8416 1551-1552 -RRB- denotes )
T8417 1552-1553 . denotes .
T8418 1553-1579 sentence denotes pe, pigmented epithelium.
T8419 1554-1556 NN denotes pe
T8420 1556-1558 , denotes ,
T8421 1558-1567 JJ denotes pigmented
T8422 1568-1578 NN denotes epithelium
T8423 1578-1579 . denotes .
T8424 1579-1599 sentence denotes is, inner segments.
T8425 1580-1582 NN denotes is
T8426 1582-1584 , denotes ,
T8427 1584-1589 JJ denotes inner
T8428 1590-1598 NNS denotes segments
T8429 1598-1599 . denotes .
T8430 1599-1625 sentence denotes onl, outer nuclear layer.
T8431 1600-1603 NN denotes onl
T8432 1603-1605 , denotes ,
T8433 1605-1610 JJ denotes outer
T8434 1619-1624 NN denotes layer
T8435 1611-1618 JJ denotes nuclear
T8436 1624-1625 . denotes .
T8437 1625-1643 sentence denotes Scale bar = 2 μm.
T8438 1626-1631 NN denotes Scale
T8439 1632-1635 NN denotes bar
T8440 1640-1642 NN denotes μm
T8441 1636-1637 SYM denotes =
T8442 1638-1639 CD denotes 2
T8443 1642-1643 . denotes .
T8570 2532-2544 NN denotes Transmission
T8571 2554-2564 NN denotes micrograph
T8572 2545-2553 NN denotes electron
T8573 2565-2567 IN denotes of
T8574 2568-2571 NN denotes Crx
T8575 2575-2581 NN denotes retina
T8576 2571-2572 SYM denotes -
T8577 2572-2573 HYPH denotes /
T8578 2573-2574 SYM denotes -
T8579 2582-2584 IN denotes at
T8580 2585-2588 NN denotes P21
T8581 2589-2590 -LRB- denotes (
T8582 2590-2591 NN denotes A
T8583 2592-2595 CC denotes and
T8584 2596-2597 NN denotes B
T8585 2597-2598 -RRB- denotes )
T8586 2598-2600 , denotes ,
T8587 2600-2603 CC denotes and
T8588 2604-2612 VBG denotes scanning
T8589 2622-2632 NN denotes micrograph
T8590 2613-2621 NN denotes electron
T8591 2633-2635 IN denotes of
T8592 2636-2639 NN denotes Crx
T8593 2639-2640 SYM denotes -
T8594 2640-2641 HYPH denotes /
T8595 2641-2642 SYM denotes -
T8596 2643-2645 IN denotes at
T8597 2646-2649 NN denotes P10
T8598 2650-2651 -LRB- denotes (
T8599 2651-2652 NN denotes C
T8600 2652-2653 -RRB- denotes )
T8601 2654-2656 IN denotes of
T8602 2657-2662 JJ denotes outer
T8603 2663-2670 NN denotes segment
T8604 2671-2676 NN denotes layer
T8605 2676-2677 . denotes .
T8606 2677-2751 sentence denotes (A) Evidence of ciliogenesis in the photoreceptor layer of Crx-/- retina.
T8607 2678-2679 -LRB- denotes (
T8608 2679-2680 LS denotes A
T8609 2682-2690 NN denotes Evidence
T8610 2680-2681 -RRB- denotes )
T8611 2691-2693 IN denotes of
T8612 2694-2706 NN denotes ciliogenesis
T8613 2707-2709 IN denotes in
T8614 2710-2713 DT denotes the
T8615 2728-2733 NN denotes layer
T8616 2714-2727 NN denotes photoreceptor
T8617 2734-2736 IN denotes of
T8618 2737-2740 NN denotes Crx
T8619 2744-2750 NN denotes retina
T8620 2740-2741 SYM denotes -
T8621 2741-2742 HYPH denotes /
T8622 2742-2743 SYM denotes -
T8623 2750-2751 . denotes .
T8624 2751-2848 sentence denotes Nonmotile connecting cilia were observed in cross section (arrowheads 1,2, and 3, for examples).
T8625 2752-2761 JJ denotes Nonmotile
T8626 2773-2778 NNS denotes cilia
T8627 2762-2772 VBG denotes connecting
T8628 2784-2792 VBN denotes observed
T8629 2779-2783 VBD denotes were
T8630 2793-2795 IN denotes in
T8631 2796-2801 NN denotes cross
T8632 2802-2809 NN denotes section
T8633 2810-2811 -LRB- denotes (
T8634 2822-2823 CD denotes 1
T8635 2811-2821 NNS denotes arrowheads
T8636 2823-2824 , denotes ,
T8637 2824-2825 CD denotes 2
T8638 2825-2827 , denotes ,
T8639 2827-2830 CC denotes and
T8640 2831-2832 CD denotes 3
T8641 2832-2834 , denotes ,
T8642 2834-2837 IN denotes for
T8643 2838-2846 NNS denotes examples
T8644 2846-2847 -RRB- denotes )
T8645 2847-2848 . denotes .
T8646 2848-2966 sentence denotes Connecting cilium 1 (arrowhead 1) demonstrated seven microtuble doublets, while cilium 2 and cilium 3 exhibited nine.
T8647 2849-2859 VBG denotes Connecting
T8648 2860-2866 NN denotes cilium
T8649 2883-2895 VBD denotes demonstrated
T8650 2867-2868 CD denotes 1
T8651 2869-2870 -LRB- denotes (
T8652 2870-2879 NN denotes arrowhead
T8653 2880-2881 CD denotes 1
T8654 2881-2882 -RRB- denotes )
T8655 2896-2901 CD denotes seven
T8656 2913-2921 NNS denotes doublets
T8657 2902-2912 JJ denotes microtuble
T8658 2921-2923 , denotes ,
T8659 2923-2928 IN denotes while
T8660 2951-2960 VBD denotes exhibited
T8661 2929-2935 NN denotes cilium
T8662 2936-2937 CD denotes 2
T8663 2938-2941 CC denotes and
T8664 2942-2948 NN denotes cilium
T8665 2949-2950 CD denotes 3
T8666 2961-2965 CD denotes nine
T8667 2965-2966 . denotes .
T8668 2966-3241 sentence denotes In A, a displaced cell nucleus (n) appearing pyknotic and abnormal deposition of matrix (mx) material of unknown identity were seen, along with large amounts of membranous vesicles (arrow) which filled the photoreceptor space and appeared to be released from inner segments.
T8669 2967-2969 IN denotes In
T8670 3094-3098 VBN denotes seen
T8671 2970-2971 NN denotes A
T8672 2971-2973 , denotes ,
T8673 2973-2974 DT denotes a
T8674 2990-2997 NN denotes nucleus
T8675 2975-2984 VBN denotes displaced
T8676 2985-2989 NN denotes cell
T8677 2998-2999 -LRB- denotes (
T8678 2999-3000 NN denotes n
T8679 3000-3001 -RRB- denotes )
T8680 3002-3011 VBG denotes appearing
T8681 3012-3020 JJ denotes pyknotic
T8682 3021-3024 CC denotes and
T8683 3025-3033 JJ denotes abnormal
T8684 3034-3044 NN denotes deposition
T8685 3045-3047 IN denotes of
T8686 3048-3054 NN denotes matrix
T8687 3060-3068 NN denotes material
T8688 3055-3056 -LRB- denotes (
T8689 3056-3058 NN denotes mx
T8690 3058-3059 -RRB- denotes )
T8691 3069-3071 IN denotes of
T8692 3072-3079 JJ denotes unknown
T8693 3080-3088 NN denotes identity
T8694 3089-3093 VBD denotes were
T8695 3098-3100 , denotes ,
T8696 3100-3105 IN denotes along
T8697 3106-3110 IN denotes with
T8698 3111-3116 JJ denotes large
T8699 3117-3124 NNS denotes amounts
T8700 3125-3127 IN denotes of
T8701 3128-3138 JJ denotes membranous
T8702 3139-3147 NNS denotes vesicles
T8703 3148-3149 -LRB- denotes (
T8704 3149-3154 NN denotes arrow
T8705 3154-3155 -RRB- denotes )
T8706 3156-3161 WDT denotes which
T8707 3162-3168 VBD denotes filled
T8708 3169-3172 DT denotes the
T8709 3187-3192 NN denotes space
T8710 3173-3186 NN denotes photoreceptor
T8711 3193-3196 CC denotes and
T8712 3197-3205 VBD denotes appeared
T8713 3206-3208 TO denotes to
T8714 3212-3220 VBN denotes released
T8715 3209-3211 VB denotes be
T8716 3221-3225 IN denotes from
T8717 3226-3231 JJ denotes inner
T8718 3232-3240 NNS denotes segments
T8719 3240-3241 . denotes .
T8720 3241-3261 sentence denotes Scale bar = 3.7 μm.
T8721 3242-3247 NN denotes Scale
T8722 3248-3251 NN denotes bar
T8723 3258-3260 NN denotes μm
T8724 3252-3253 SYM denotes =
T8725 3254-3257 CD denotes 3.7
T8726 3260-3261 . denotes .
T8727 3261-3411 sentence denotes (B) Nonmotile connecting cilium in cross section, from a Crx-/- photoreceptor, demonstrating characteristic 9+0 radial array of microtubule doublets.
T8728 3262-3263 -LRB- denotes (
T8729 3263-3264 LS denotes B
T8730 3287-3293 NN denotes cilium
T8731 3264-3265 -RRB- denotes )
T8732 3266-3275 JJ denotes Nonmotile
T8733 3276-3286 VBG denotes connecting
T8734 3294-3296 IN denotes in
T8735 3297-3302 NN denotes cross
T8736 3303-3310 NN denotes section
T8737 3310-3312 , denotes ,
T8738 3312-3316 IN denotes from
T8739 3317-3318 DT denotes a
T8740 3326-3339 NN denotes photoreceptor
T8741 3319-3322 NN denotes Crx
T8742 3322-3323 SYM denotes -
T8743 3323-3324 HYPH denotes /
T8744 3324-3325 SYM denotes -
T8745 3339-3341 , denotes ,
T8746 3341-3354 VBG denotes demonstrating
T8747 3355-3369 JJ denotes characteristic
T8748 3381-3386 NN denotes array
T8749 3370-3371 CD denotes 9
T8750 3372-3373 CD denotes 0
T8751 3371-3372 SYM denotes +
T8752 3374-3380 JJ denotes radial
T8753 3387-3389 IN denotes of
T8754 3390-3401 NN denotes microtubule
T8755 3402-3410 NNS denotes doublets
T8756 3410-3411 . denotes .
T8757 3411-3430 sentence denotes Scale bar = 88 nm.
T8758 3412-3417 NN denotes Scale
T8759 3418-3421 NN denotes bar
T8760 3427-3429 NN denotes nm
T8761 3422-3423 SYM denotes =
T8762 3424-3426 CD denotes 88
T8763 3429-3430 . denotes .
T8764 3430-3576 sentence denotes (C) Scanning electron micrograph (SEM) of membranous vesicles (arrow shows one example) shed from inner segments of Crx-/- photoreceptors at P10.
T8765 3431-3432 -LRB- denotes (
T8766 3432-3433 LS denotes C
T8767 3453-3463 NN denotes micrograph
T8768 3433-3434 -RRB- denotes )
T8769 3435-3443 VBG denotes Scanning
T8770 3444-3452 NN denotes electron
T8771 3464-3465 -LRB- denotes (
T8772 3465-3468 NN denotes SEM
T8773 3468-3469 -RRB- denotes )
T8774 3470-3472 IN denotes of
T8775 3473-3483 JJ denotes membranous
T8776 3484-3492 NNS denotes vesicles
T8777 3493-3494 -LRB- denotes (
T8778 3500-3505 VBZ denotes shows
T8779 3494-3499 NN denotes arrow
T8780 3506-3509 CD denotes one
T8781 3510-3517 NN denotes example
T8782 3517-3518 -RRB- denotes )
T8783 3519-3523 VBN denotes shed
T8784 3524-3528 IN denotes from
T8785 3529-3534 JJ denotes inner
T8786 3535-3543 NNS denotes segments
T8787 3544-3546 IN denotes of
T8788 3547-3550 NN denotes Crx
T8789 3554-3568 NNS denotes photoreceptors
T8790 3550-3551 SYM denotes -
T8791 3551-3552 HYPH denotes /
T8792 3552-3553 SYM denotes -
T8793 3569-3571 IN denotes at
T8794 3572-3575 NN denotes P10
T8795 3575-3576 . denotes .
T8796 3576-3672 sentence denotes Figure shows inner segments viewed from the scleral side with the pigmented epithelium removed.
T8797 3577-3583 NN denotes Figure
T8798 3584-3589 VBZ denotes shows
T8799 3590-3595 JJ denotes inner
T8800 3596-3604 NNS denotes segments
T8801 3605-3611 VBN denotes viewed
T8802 3612-3616 IN denotes from
T8803 3617-3620 DT denotes the
T8804 3629-3633 NN denotes side
T8805 3621-3628 JJ denotes scleral
T8806 3634-3638 IN denotes with
T8807 3664-3671 VBN denotes removed
T8808 3639-3642 DT denotes the
T8809 3653-3663 NN denotes epithelium
T8810 3643-3652 VBN denotes pigmented
T8811 3671-3672 . denotes .
T8812 3672-3690 sentence denotes Scale bar = 1 μm.
T8813 3673-3678 NN denotes Scale
T8814 3679-3682 NN denotes bar
T8815 3687-3689 NN denotes μm
T8816 3683-3684 SYM denotes =
T8817 3685-3686 CD denotes 1
T8818 3689-3690 . denotes .
T8923 6345-6350 NN denotes Outer
T8924 6351-6358 NN denotes segment
T8925 6359-6372 NN denotes morphogenesis
T8926 6373-6375 IN denotes in
T8927 6376-6379 NN denotes Crx
T8928 6383-6397 NNS denotes photoreceptors
T8929 6379-6380 SYM denotes -
T8930 6380-6381 HYPH denotes /
T8931 6381-6382 SYM denotes -
T8932 6397-6398 . denotes .
T8933 6398-6602 sentence denotes Scanning electron microscopy of developing photoreceptors viewed from the scleral side with the pigmented epithelium removed at P7, P14, and P21 for Crx+/+ (A, C, and E) and Crx-/- (B, D, F) littermates.
T8934 6399-6407 VBG denotes Scanning
T8935 6417-6427 NN denotes microscopy
T8936 6408-6416 NN denotes electron
T8937 6428-6430 IN denotes of
T8938 6431-6441 VBG denotes developing
T8939 6442-6456 NNS denotes photoreceptors
T8940 6457-6463 VBN denotes viewed
T8941 6464-6468 IN denotes from
T8942 6469-6472 DT denotes the
T8943 6481-6485 NN denotes side
T8944 6473-6480 JJ denotes scleral
T8945 6486-6490 IN denotes with
T8946 6516-6523 VBN denotes removed
T8947 6491-6494 DT denotes the
T8948 6505-6515 NN denotes epithelium
T8949 6495-6504 JJ denotes pigmented
T8950 6524-6526 IN denotes at
T8951 6527-6529 NN denotes P7
T8952 6529-6531 , denotes ,
T8953 6531-6534 NN denotes P14
T8954 6534-6536 , denotes ,
T8955 6536-6539 CC denotes and
T8956 6540-6543 NN denotes P21
T8957 6544-6547 IN denotes for
T8958 6548-6551 NN denotes Crx
T8959 6590-6601 NNS denotes littermates
T8960 6551-6552 SYM denotes +
T8961 6552-6553 HYPH denotes /
T8962 6553-6554 SYM denotes +
T8963 6555-6556 -LRB- denotes (
T8964 6556-6557 NN denotes A
T8965 6557-6559 , denotes ,
T8966 6559-6560 NN denotes C
T8967 6560-6562 , denotes ,
T8968 6562-6565 CC denotes and
T8969 6566-6567 NN denotes E
T8970 6567-6568 -RRB- denotes )
T8971 6569-6572 CC denotes and
T8972 6573-6576 NN denotes Crx
T8973 6576-6577 SYM denotes -
T8974 6577-6578 HYPH denotes /
T8975 6578-6579 SYM denotes -
T8976 6580-6581 -LRB- denotes (
T8977 6587-6588 NN denotes F
T8978 6581-6582 NN denotes B
T8979 6582-6584 , denotes ,
T8980 6584-6585 NN denotes D
T8981 6585-6587 , denotes ,
T8982 6588-6589 -RRB- denotes )
T8983 6601-6602 . denotes .
T8984 6602-6706 sentence denotes In Crx+/+ retina, numerous connecting cilia (A, cc) were evident at P7 with rudimentary outer segments.
T8985 6603-6605 IN denotes In
T8986 6655-6659 VBD denotes were
T8987 6606-6609 NN denotes Crx
T8988 6613-6619 NN denotes retina
T8989 6609-6610 SYM denotes +
T8990 6610-6611 HYPH denotes /
T8991 6611-6612 SYM denotes +
T8992 6619-6621 , denotes ,
T8993 6621-6629 JJ denotes numerous
T8994 6641-6646 NNS denotes cilia
T8995 6630-6640 VBG denotes connecting
T8996 6647-6648 -LRB- denotes (
T8997 6651-6653 NN denotes cc
T8998 6648-6649 NN denotes A
T8999 6649-6651 , denotes ,
T9000 6653-6654 -RRB- denotes )
T9001 6660-6667 JJ denotes evident
T9002 6668-6670 IN denotes at
T9003 6671-6673 NN denotes P7
T9004 6674-6678 IN denotes with
T9005 6679-6690 JJ denotes rudimentary
T9006 6697-6705 NNS denotes segments
T9007 6691-6696 JJ denotes outer
T9008 6705-6706 . denotes .
T9009 6706-6759 sentence denotes After P7, in Crx+/+ outer segment elongation occurs.
T9010 6707-6712 IN denotes After
T9011 6752-6758 VBZ denotes occurs
T9012 6713-6715 NN denotes P7
T9013 6715-6717 , denotes ,
T9014 6717-6719 IN denotes in
T9015 6720-6723 NN denotes Crx
T9016 6723-6724 SYM denotes +
T9017 6724-6725 HYPH denotes /
T9018 6725-6726 SYM denotes +
T9019 6727-6732 JJ denotes outer
T9020 6733-6740 NN denotes segment
T9021 6741-6751 NN denotes elongation
T9022 6758-6759 . denotes .
T9023 6759-6851 sentence denotes Initially, outer segments have a paddle-like structure (C, os) which is later shed (E, os).
T9024 6760-6769 RB denotes Initially
T9025 6786-6790 VBP denotes have
T9026 6769-6771 , denotes ,
T9027 6771-6776 JJ denotes outer
T9028 6777-6785 NNS denotes segments
T9029 6791-6792 DT denotes a
T9030 6805-6814 NN denotes structure
T9031 6793-6799 NN denotes paddle
T9032 6800-6804 JJ denotes like
T9033 6799-6800 HYPH denotes -
T9034 6815-6816 -LRB- denotes (
T9035 6819-6821 NN denotes os
T9036 6816-6817 NN denotes C
T9037 6817-6819 , denotes ,
T9038 6821-6822 -RRB- denotes )
T9039 6823-6828 WDT denotes which
T9040 6838-6842 VBN denotes shed
T9041 6829-6831 VBZ denotes is
T9042 6832-6837 RB denotes later
T9043 6843-6844 -LRB- denotes (
T9044 6847-6849 NN denotes os
T9045 6844-6845 NN denotes E
T9046 6845-6847 , denotes ,
T9047 6849-6850 -RRB- denotes )
T9048 6850-6851 . denotes .
T9049 6851-6927 sentence denotes In Crx-/- photoreceptors, few connecting cilia were observed at P7 (B, cc).
T9050 6852-6854 IN denotes In
T9051 6904-6912 VBN denotes observed
T9052 6855-6858 NN denotes Crx
T9053 6862-6876 NNS denotes photoreceptors
T9054 6858-6859 SYM denotes -
T9055 6859-6860 HYPH denotes /
T9056 6860-6861 SYM denotes -
T9057 6876-6878 , denotes ,
T9058 6878-6881 JJ denotes few
T9059 6893-6898 NNS denotes cilia
T9060 6882-6892 VBG denotes connecting
T9061 6899-6903 VBD denotes were
T9062 6913-6915 IN denotes at
T9063 6916-6918 NN denotes P7
T9064 6919-6920 -LRB- denotes (
T9065 6923-6925 NN denotes cc
T9066 6920-6921 NN denotes B
T9067 6921-6923 , denotes ,
T9068 6925-6926 -RRB- denotes )
T9069 6926-6927 . denotes .
T9070 6927-7077 sentence denotes After P7, connecting cilia were more numerous and occasionally a malformed outer segment was noted extending from a connecting cilium (D and F, cc*).
T9071 6928-6933 IN denotes After
T9072 6955-6959 VBD denotes were
T9073 6934-6936 NN denotes P7
T9074 6936-6938 , denotes ,
T9075 6938-6948 VBG denotes connecting
T9076 6949-6954 NNS denotes cilia
T9077 6960-6964 RBR denotes more
T9078 6965-6973 JJ denotes numerous
T9079 6974-6977 CC denotes and
T9080 6978-6990 RB denotes occasionally
T9081 7021-7026 VBN denotes noted
T9082 6991-6992 DT denotes a
T9083 7009-7016 NN denotes segment
T9084 6993-7002 JJ denotes malformed
T9085 7003-7008 JJ denotes outer
T9086 7017-7020 VBD denotes was
T9087 7027-7036 VBG denotes extending
T9088 7037-7041 IN denotes from
T9089 7042-7043 DT denotes a
T9090 7055-7061 NN denotes cilium
T9091 7044-7054 VBG denotes connecting
T9092 7062-7063 -LRB- denotes (
T9093 7072-7075 NN denotes cc*
T9094 7063-7064 NN denotes D
T9095 7065-7068 CC denotes and
T9096 7069-7070 NN denotes F
T9097 7070-7072 , denotes ,
T9098 7075-7076 -RRB- denotes )
T9099 7076-7077 . denotes .
T9100 7077-7140 sentence denotes These were rarely observed in Crx+/+ and only at P14 (C, cc*).
T9101 7078-7083 DT denotes These
T9102 7096-7104 VBN denotes observed
T9103 7084-7088 VBD denotes were
T9104 7089-7095 RB denotes rarely
T9105 7105-7107 IN denotes in
T9106 7108-7111 NN denotes Crx
T9107 7111-7112 SYM denotes +
T9108 7112-7113 HYPH denotes /
T9109 7113-7114 SYM denotes +
T9110 7115-7118 CC denotes and
T9111 7119-7123 RB denotes only
T9112 7124-7126 IN denotes at
T9113 7127-7130 NN denotes P14
T9114 7131-7132 -LRB- denotes (
T9115 7135-7138 NN denotes cc*
T9116 7132-7133 NN denotes C
T9117 7133-7135 , denotes ,
T9118 7138-7139 -RRB- denotes )
T9119 7139-7140 . denotes .
T9120 7140-7210 sentence denotes At P21, abnormally long connecting cilia are noted in Crx-/- (F, cc).
T9121 7141-7143 IN denotes At
T9122 7186-7191 VBN denotes noted
T9123 7144-7147 NN denotes P21
T9124 7147-7149 , denotes ,
T9125 7149-7159 RB denotes abnormally
T9126 7160-7164 JJ denotes long
T9127 7176-7181 NNS denotes cilia
T9128 7165-7175 VBG denotes connecting
T9129 7182-7185 VBP denotes are
T9130 7192-7194 IN denotes in
T9131 7195-7198 NN denotes Crx
T9132 7198-7199 SYM denotes -
T9133 7199-7200 HYPH denotes /
T9134 7200-7201 SYM denotes -
T9135 7202-7203 -LRB- denotes (
T9136 7206-7208 NN denotes cc
T9137 7203-7204 NN denotes F
T9138 7204-7206 , denotes ,
T9139 7208-7209 -RRB- denotes )
T9140 7209-7210 . denotes .
T9141 7210-7229 sentence denotes Scale bars = 10 μm
T9142 7211-7216 NN denotes Scale
T9143 7217-7221 NNS denotes bars
T9144 7227-7229 NN denotes μm
T9145 7222-7223 SYM denotes =
T9146 7224-7226 CD denotes 10
T9204 7240-7252 NN denotes Transmission
T9205 7262-7273 NNS denotes micrographs
T9206 7253-7261 NN denotes electron
T9207 7274-7276 IN denotes of
T9208 7277-7280 NN denotes Crx
T9209 7284-7298 NNS denotes photoreceptors
T9210 7280-7281 SYM denotes -
T9211 7281-7282 HYPH denotes /
T9212 7282-7283 SYM denotes -
T9213 7299-7301 IN denotes in
T9214 7302-7305 DT denotes the
T9215 7320-7325 NN denotes layer
T9216 7306-7319 NN denotes photoreceptor
T9217 7326-7328 IN denotes at
T9218 7329-7331 NN denotes P7
T9219 7331-7332 . denotes .
T9220 7332-7479 sentence denotes (A) Photoreceptor layer of Crx+/+ retina demonstrating nascent outer segment structures (arrow) emerging from photoreceptor connecting cilia (cc).
T9221 7333-7334 -LRB- denotes (
T9222 7334-7335 LS denotes A
T9223 7351-7356 NN denotes layer
T9224 7335-7336 -RRB- denotes )
T9225 7337-7350 NN denotes Photoreceptor
T9226 7357-7359 IN denotes of
T9227 7360-7363 NN denotes Crx
T9228 7367-7373 NN denotes retina
T9229 7363-7364 SYM denotes +
T9230 7364-7365 HYPH denotes /
T9231 7365-7366 SYM denotes +
T9232 7374-7387 VBG denotes demonstrating
T9233 7388-7395 JJ denotes nascent
T9234 7410-7420 NNS denotes structures
T9235 7396-7401 JJ denotes outer
T9236 7402-7409 NN denotes segment
T9237 7429-7437 VBG denotes emerging
T9238 7421-7422 -LRB- denotes (
T9239 7422-7427 NN denotes arrow
T9240 7427-7428 -RRB- denotes )
T9241 7438-7442 IN denotes from
T9242 7443-7456 NN denotes photoreceptor
T9243 7468-7473 NNS denotes cilia
T9244 7457-7467 VBG denotes connecting
T9245 7474-7475 -LRB- denotes (
T9246 7475-7477 NN denotes cc
T9247 7477-7478 -RRB- denotes )
T9248 7478-7479 . denotes .
T9249 7479-7619 sentence denotes (B) Crx-/- photoreceptors exhibited connecting cilia (cc) at this early stage, however, nascent outer segment structures were not observed.
T9250 7480-7481 -LRB- denotes (
T9251 7481-7482 LS denotes B
T9252 7610-7618 VBN denotes observed
T9253 7482-7483 -RRB- denotes )
T9254 7484-7487 NN denotes Crx
T9255 7491-7505 NNS denotes photoreceptors
T9256 7487-7488 SYM denotes -
T9257 7488-7489 HYPH denotes /
T9258 7489-7490 SYM denotes -
T9259 7506-7515 VBD denotes exhibited
T9260 7516-7526 VBG denotes connecting
T9261 7527-7532 NNS denotes cilia
T9262 7533-7534 -LRB- denotes (
T9263 7534-7536 NN denotes cc
T9264 7536-7537 -RRB- denotes )
T9265 7538-7540 IN denotes at
T9266 7541-7545 DT denotes this
T9267 7552-7557 NN denotes stage
T9268 7546-7551 JJ denotes early
T9269 7557-7559 , denotes ,
T9270 7559-7566 RB denotes however
T9271 7566-7568 , denotes ,
T9272 7568-7575 JJ denotes nascent
T9273 7590-7600 NNS denotes structures
T9274 7576-7581 JJ denotes outer
T9275 7582-7589 NN denotes segment
T9276 7601-7605 VBD denotes were
T9277 7606-7609 RB denotes not
T9278 7618-7619 . denotes .
T9279 7619-7637 sentence denotes Scale Bar = 1 μm.
T9280 7620-7625 NN denotes Scale
T9281 7626-7629 NN denotes Bar
T9282 7634-7636 NN denotes μm
T9283 7630-7631 SYM denotes =
T9284 7632-7633 CD denotes 1
T9285 7636-7637 . denotes .
T9319 8228-8236 VBG denotes Scanning
T9320 8246-8256 NN denotes microscopy
T9321 8237-8245 NN denotes electron
T9322 8257-8259 IN denotes of
T9323 8260-8270 NN denotes peripherin
T9324 8299-8313 NNS denotes photoreceptors
T9325 8270-8271 SYM denotes -
T9326 8271-8272 HYPH denotes /
T9327 8272-8273 SYM denotes -
T9328 8274-8275 -LRB- denotes (
T9329 8275-8276 NN denotes A
T9330 8276-8277 -RRB- denotes )
T9331 8278-8281 CC denotes and
T9332 8282-8291 NN denotes rhodopsin
T9333 8291-8292 SYM denotes -
T9334 8292-8293 HYPH denotes /
T9335 8293-8294 SYM denotes -
T9336 8295-8296 -LRB- denotes (
T9337 8296-8297 NN denotes B
T9338 8297-8298 -RRB- denotes )
T9339 8314-8316 IN denotes at
T9340 8317-8320 NN denotes P21
T9341 8320-8322 , denotes ,
T9342 8322-8328 VBN denotes viewed
T9343 8329-8333 IN denotes from
T9344 8334-8337 DT denotes the
T9345 8346-8350 NN denotes side
T9346 8338-8345 JJ denotes scleral
T9347 8351-8355 IN denotes with
T9348 8381-8388 VBN denotes removed
T9349 8356-8359 DT denotes the
T9350 8370-8380 NN denotes epithelium
T9351 8360-8369 JJ denotes pigmented
T9352 8388-8389 . denotes .
T9353 8389-8412 sentence denotes cc, connecting cilium.
T9354 8390-8392 NN denotes cc
T9355 8392-8394 , denotes ,
T9356 8394-8404 VBG denotes connecting
T9357 8405-8411 NN denotes cilium
T9358 8411-8412 . denotes .
T9359 8412-8431 sentence denotes is, inner segment.
T9360 8413-8415 NN denotes is
T9361 8415-8417 , denotes ,
T9362 8417-8422 JJ denotes inner
T9363 8423-8430 NN denotes segment
T9364 8430-8431 . denotes .
T9365 8431-8450 sentence denotes Scale bar = 10 μm.
T9366 8432-8437 NN denotes Scale
T9367 8438-8441 NN denotes bar
T9368 8447-8449 NN denotes μm
T9369 8442-8443 SYM denotes =
T9370 8444-8446 CD denotes 10
T9371 8449-8450 . denotes .
T2556 959-961 , denotes ,
T2557 961-963 DT denotes an
T2558 970-977 NN denotes segment
T2559 964-969 JJ denotes inner
T2560 978-988 VBG denotes undergoing
T2561 989-994 NN denotes lysis
T2562 995-998 VBD denotes was
T2563 1004-1006 , denotes ,
T2564 1006-1015 VBG denotes appearing
T2565 1016-1023 VBN denotes swollen
T2566 1024-1026 CC denotes or
T2567 1027-1031 IN denotes with
T2568 1032-1040 NNS denotes vacuoles
T2569 1041-1044 CC denotes and
T2570 1045-1052 VBN denotes swollen
T2571 1053-1065 NNS denotes mitochondria
T2572 1066-1067 -LRB- denotes (
T2573 1076-1081 VBN denotes shown
T2574 1067-1071 NNS denotes data
T2575 1072-1075 RB denotes not
T2576 1081-1082 -RRB- denotes )
T2577 1082-1083 . denotes .
T2578 1083-1084 sentence denotes
T2579 1644-1645 sentence denotes P
T2580 1644-1645 NN denotes P
T2581 1645-1646 sentence denotes h
T2582 1645-1646 NN denotes h
T2583 1646-1648 sentence denotes ot
T2584 1646-1647 NN denotes o
T2585 1647-1648 JJ denotes t
T2586 1648-1659 sentence denotes oreceptor i
T2587 1648-1649 NN denotes o
T2588 1649-1650 JJ denotes r
T2589 1650-1651 JJ denotes e
T2548 930-936 NN denotes Figure
T2549 939-942 CC denotes and
T2550 943-944 CD denotes 2
T2551 944-945 -RRB- denotes )
T2552 945-946 . denotes .
T2553 946-1083 sentence denotes Occasionally, an inner segment undergoing lysis was noted, appearing swollen or with vacuoles and swollen mitochondria (data not shown).
T2554 947-959 RB denotes Occasionally
T2555 999-1004 VBN denotes noted
T2590 1651-1657 NN denotes ceptor
T2591 1658-1659 NNS denotes i
T2592 1659-1660 sentence denotes n
T2593 1659-1660 CC denotes n
T2594 1660-1671 sentence denotes ner segment
T2595 1660-1661 NN denotes n
T2596 1661-1663 NN denotes er
T2597 1664-1671 NN denotes segment
T2598 1671-1679 sentence denotes s and ou
T2599 1671-1672 NNS denotes s
T2600 1673-1674 NNS denotes a
T2601 1674-1676 VBN denotes nd
T2602 1677-1678 NN denotes o
T2603 1678-1679 NN denotes u
T2604 1679-1681 sentence denotes te
T2605 1679-1681 JJ denotes te
T2606 1681-1691 sentence denotes r segments
T2607 1681-1682 JJ denotes r
T2608 1683-1691 NNS denotes segments
T2609 1691-1695 sentence denotes are
T2610 1694-1695 NN denotes e
T2611 1692-1694 JJ denotes ar
T2612 1695-1696 sentence denotes
T2613 1696-1839 sentence denotes joined by a non-motile connecting cilium that exhibits a characteristic 9 + 0 arrangement of microtubule doublets when viewed in cross-section.
T2614 1696-1702 VBN denotes joined
T2615 1703-1705 IN denotes by
T2616 1706-1707 DT denotes a
T2617 1730-1736 NN denotes cilium
T2618 1708-1718 JJ denotes non-motile
T2619 1719-1729 JJ denotes connecting
T2620 1737-1741 WDT denotes that
T2621 1742-1750 VBZ denotes exhibits
T2622 1751-1752 DT denotes a
T2623 1774-1785 NN denotes arrangement
T2624 1753-1767 JJ denotes characteristic
T2625 1768-1769 CD denotes 9
T2626 1772-1773 CD denotes 0
T2627 1770-1771 SYM denotes +
T2628 1786-1788 IN denotes of
T2629 1789-1800 NN denotes microtubule
T2630 1801-1809 NNS denotes doublets
T2631 1810-1814 WRB denotes when
T2632 1815-1821 VBN denotes viewed
T2633 1822-1824 IN denotes in
T2634 1825-1838 NN denotes cross-section
T2635 1838-1839 . denotes .
T2636 1839-1941 sentence denotes At P21, in Crx-/- retinas, numerous cross sections of connecting cilia were noted (Figure 3A and 3B).
T2637 1840-1842 IN denotes At
T2638 1916-1921 VBN denotes noted
T2639 1843-1846 NN denotes P21
T2640 1846-1848 , denotes ,
T2747 2378-2385 RB denotes Further
T2748 2443-2451 VBD denotes appeared
T2749 2385-2387 , denotes ,
T2750 2387-2389 IN denotes in
T2751 2390-2393 NN denotes Crx
T2752 2397-2404 NNS denotes retinas
T2753 2393-2394 SYM denotes -
T2754 2394-2395 HYPH denotes /
T2755 2395-2396 SYM denotes -
T2756 2405-2408 DT denotes the
T2757 2427-2437 NN denotes epithelium
T2758 2409-2416 NN denotes retinal
T2759 2417-2426 VBN denotes pigmented
T2760 2438-2439 -LRB- denotes (
T2761 2439-2441 NN denotes PE
T2762 2441-2442 -RRB- denotes )
T2763 2452-2458 JJ denotes normal
T2764 2458-2460 , denotes ,
T2765 2460-2462 RB denotes at
T2766 2463-2468 RBS denotes least
T2767 2469-2471 IN denotes up
T2768 2472-2474 IN denotes to
T2769 2475-2478 NN denotes P21
T2770 2479-2480 -LRB- denotes (
T2771 2489-2494 VBN denotes shown
T2772 2480-2484 NNS denotes data
T2773 2485-2488 RB denotes not
T2774 2494-2495 -RRB- denotes )
T2775 2495-2497 , denotes ,
T2776 2497-2500 DT denotes the
T2777 2508-2511 NN denotes age
T2778 2501-2507 JJS denotes oldest
T2779 2512-2520 VBN denotes examined
T2780 2520-2521 . denotes .
T2781 2521-2522 sentence denotes
T2782 3691-3713 sentence denotes In addition to the com
T2783 3691-3693 IN denotes In
T2784 3694-3695 DT denotes a
T2785 3695-3697 VBN denotes dd
T2786 3697-3698 VBG denotes i
T2787 3698-3700 JJ denotes ti
T2788 3700-3701 JJ denotes o
T2789 3701-3702 NN denotes n
T2790 3703-3704 NN denotes t
T2791 3704-3705 IN denotes o
T2792 3706-3707 NN denotes t
T2793 3707-3708 IN denotes h
T2794 3708-3709 JJ denotes e
T2795 3710-3711 NNS denotes c
T2796 3711-3712 NN denotes o
T2797 3712-3713 IN denotes m
T2798 3713-3717 sentence denotes plet
T2799 3713-3714 NN denotes p
T2800 3714-3715 JJ denotes l
T2801 3715-3716 NN denotes e
T2802 3716-3717 NNS denotes t
T2803 3717-3720 sentence denotes e a
T2804 3717-3718 NN denotes e
T2805 3719-3720 NN denotes a
T2806 3720-3727 sentence denotes bsence
T2807 3720-3722 JJ denotes bs
T2808 3722-3723 NNS denotes e
T2809 3723-3724 CD denotes n
T2810 3724-3726 NNS denotes ce
T2811 3727-3731 sentence denotes of o
T2812 3727-3728 VBZ denotes o
T2813 3728-3729 IN denotes f
T2814 3730-3731 VBN denotes o
T2815 3731-3830 sentence denotes uter segments, Crx-/- retinas exhibited three other notable pathologies in the outer segment layer.
T2816 3761-3770 VBD denotes exhibited
T2817 3731-3735 JJ denotes uter
T2818 3736-3744 NNS denotes segments
T2819 3744-3746 , denotes ,
T2820 3746-3749 NN denotes Crx
T2821 3753-3760 NNS denotes retinas
T2822 3749-3750 SYM denotes -
T2823 3750-3751 HYPH denotes /
T2824 3751-3752 SYM denotes -
T2825 3771-3776 CD denotes three
T2826 3791-3802 NNS denotes pathologies
T2827 3777-3782 JJ denotes other
T2828 3783-3790 JJ denotes notable
T2829 3803-3805 IN denotes in
T2830 3806-3809 DT denotes the
T2831 3824-3829 NN denotes layer
T2832 3810-3815 JJ denotes outer
T2833 3816-3823 NN denotes segment
T2834 3829-3830 . denotes .
T2835 3830-3917 sentence denotes First, an abnormal deposition of matrix of unknown identity was noted (Figure 3A, mx).
T3258 5920-5926 NN denotes Figure
T3259 5927-5929 NN denotes 4F
T3260 5929-5931 , denotes ,
T3261 5933-5934 -RRB- denotes )
T3262 5934-5935 . denotes .
T3263 5935-6120 sentence denotes Serial examination of Crx-/- photoreceptors at P7, P10, P14, and P21 by TEM, demonstrated a distinctive lack of any structure interpretable as orderly stacks of discs or forming discs.
T3264 5936-5942 JJ denotes Serial
T3265 5943-5954 NN denotes examination
T3266 6013-6025 VBD denotes demonstrated
T3267 5955-5957 IN denotes of
T3268 5958-5961 NN denotes Crx
T3269 5965-5979 NNS denotes photoreceptors
T3270 5961-5962 SYM denotes -
T3271 5962-5963 HYPH denotes /
T3272 5963-5964 SYM denotes -
T3273 5980-5982 IN denotes at
T3274 5983-5985 NN denotes P7
T3275 5985-5987 , denotes ,
T3345 7644-7645 sentence denotes y
T3346 7644-7645 JJ denotes y
T3347 7645-7648 sentence denotes , t
T3348 7645-7647 , denotes ,
T3349 7647-7648 JJ denotes t
T3350 7648-7651 sentence denotes he
T3351 7648-7650 VBP denotes he
T3352 7651-7654 sentence denotes mor
T3353 7651-7654 RBR denotes mor
T3354 7654-7658 sentence denotes phol
T3355 7654-7656 NNS denotes ph
T3356 7656-7657 IN denotes o
T3357 7657-7658 NN denotes l
T3358 7658-7660 sentence denotes og
T3359 7658-7659 NN denotes o
T3360 7659-7660 VBG denotes g
T3361 7660-7663 sentence denotes y o
T3362 7660-7661 JJ denotes y
T3363 7662-7663 RB denotes o
T3364 7663-7763 sentence denotes f the malformed Crx-/- photoreceptors was compared to rhodopsin-/- and peripherin-/- photoreceptors.
T3365 7705-7713 VBN denotes compared
T3366 7663-7664 IN denotes f
T3367 7665-7668 DT denotes the
T3368 7686-7700 NNS denotes photoreceptors
T3369 7669-7678 JJ denotes malformed
T3370 7679-7682 NN denotes Crx
T3371 7682-7683 SYM denotes -
T3372 7683-7684 HYPH denotes /
T3373 7684-7685 SYM denotes -
T3374 7701-7704 VBD denotes was
T3375 7714-7716 IN denotes to
T3376 7717-7726 NN denotes rhodopsin
T3377 7748-7762 NNS denotes photoreceptors
T3378 7726-7727 SYM denotes -
T3379 7727-7728 HYPH denotes /
T3380 7728-7729 SYM denotes -
T3381 7730-7733 CC denotes and
T3382 7734-7744 NN denotes peripherin
T3383 7744-7745 SYM denotes -
T3384 7745-7746 HYPH denotes /
T3385 7746-7747 SYM denotes -
T3386 7762-7763 . denotes .
T3387 7763-7907 sentence denotes Rhodopsin and peripherin are two photoreceptor-specific genes whose expression is significantly downregulated in the Crx-/- retinae [10,34,35].
R1144 T2359 T2360 amod Multiple,pathologies
R1145 T2361 T2360 prep in,pathologies
R1146 T2362 T2363 det the,layer
R1147 T2363 T2361 pobj layer,in
R1148 T2364 T2365 amod outer,segment
R1149 T2365 T2363 compound segment,layer
R1150 T2366 T2360 prep in,pathologies
R1151 T2367 T2368 nmod Crx,mice
R1152 T2368 T2366 pobj mice,in
R1153 T2369 T2367 punct -,Crx
R1154 T2370 T2367 punct /,Crx
R1155 T2371 T2367 punct -,Crx
R1156 T2373 T2374 det A,protocol
R1157 T2374 T2379 nsubjpass protocol,used
R1158 T2375 T2374 amod standard,protocol
R1159 T2376 T2374 amod knock,protocol
R1160 T2377 T2376 punct -,knock
R1161 T2378 T2376 prt out,knock
R1162 T2380 T2379 auxpass was,used
R1163 T2381 T2382 aux to,generate
R1164 T2382 T2379 advcl generate,used
R1165 T2383 T2382 dobj mice,generate
R1166 T2384 T2385 prep in,targeted
R1167 T2385 T2383 relcl targeted,mice
R1168 T2386 T2384 pobj which,in
R1169 T2387 T2388 det the,homeodomain
R1170 T2388 T2385 nsubjpass homeodomain,targeted
R1171 T2389 T2388 prep of,homeodomain
R1172 T2390 T2389 pobj Crx,of
R1173 T2391 T2390 punct -,Crx
R1174 T2392 T2390 punct /,Crx
R1175 T2393 T2390 punct -,Crx
R1176 T2394 T2385 auxpass was,targeted
R1177 T2395 T2385 cc and,targeted
R1178 T2396 T2385 conj deleted,targeted
R1179 T2397 T2379 punct .,used
R1180 T2399 T2400 nsubjpass Generation,reported
R1181 T2401 T2399 prep of,Generation
R1182 T2402 T2403 det these,mice
R1183 T2403 T2401 pobj mice,of
R1184 T2404 T2403 nmod Crx,mice
R1185 T2405 T2404 punct -,Crx
R1186 T2406 T2404 punct /,Crx
R1187 T2407 T2404 punct -,Crx
R1188 T2408 T2400 aux has,reported
R1189 T2409 T2400 auxpass been,reported
R1190 T2410 T2400 advmod elsewhere,reported
R1191 T2411 T2412 punct [,34
R1192 T2412 T2400 parataxis 34,reported
R1193 T2413 T2412 punct ],34
R1194 T2414 T2400 punct .,reported
R1195 T2416 T2417 prep In,examined
R1196 T2418 T2419 det this,study
R1197 T2419 T2416 pobj study,In
R1198 T2420 T2417 punct ", ",examined
R1199 T2421 T2417 prep in,examined
R1200 T2422 T2421 pobj order,in
R1201 T2423 T2424 aux to,characterize
R1202 T2424 T2422 acl characterize,order
R1203 T2425 T2424 advmod further,characterize
R1204 T2426 T2427 det the,role
R1205 T2427 T2424 dobj role,characterize
R1206 T2428 T2427 prep of,role
R1207 T2429 T2428 pobj Crx,of
R1208 T2430 T2427 prep in,role
R1209 T2431 T2432 compound photoreceptor,morphogenesis
R1210 T2432 T2430 pobj morphogenesis,in
R1211 T2433 T2417 punct ", ",examined
R1212 T2434 T2435 det the,retinae
R1213 T2435 T2417 nsubjpass retinae,examined
R1214 T2436 T2435 amod outer,retinae
R1215 T2437 T2435 prep from,retinae
R1216 T2438 T2439 nmod Crx,mice
R1217 T2439 T2437 pobj mice,from
R1218 T2440 T2438 punct -,Crx
R1219 T2441 T2438 punct /,Crx
R1220 T2442 T2438 punct -,Crx
R1221 T2443 T2417 auxpass were,examined
R1222 T2444 T2417 advcl using,examined
R1223 T2445 T2446 compound transmission,microscopy
R1224 T2446 T2444 dobj microscopy,using
R1225 T2447 T2446 compound electron,microscopy
R1226 T2448 T2417 punct .,examined
R1227 T2450 T2451 prep At,were
R1228 T2452 T2453 amod postnatal,day
R1229 T2453 T2450 pobj day,At
R1230 T2454 T2453 nummod 21,day
R1231 T2455 T2453 punct (,day
R1232 T2456 T2453 appos P21,day
R1233 T2457 T2451 punct ),were
R1234 T2458 T2451 punct ", ",were
R1235 T2459 T2460 advmod when,exhibited
R1236 T2460 T2451 advcl exhibited,were
R1237 T2461 T2462 nmod Crx,photoreceptors
R1238 T2462 T2460 nsubj photoreceptors,exhibited
R1239 T2463 T2461 punct +,Crx
R1240 T2464 T2461 punct /,Crx
R1241 T2465 T2461 punct +,Crx
R1242 T2466 T2467 amod robust,segments
R1243 T2467 T2460 dobj segments,exhibited
R1244 T2468 T2467 amod outer,segments
R1245 T2469 T2470 punct (,os
R1246 T2470 T2460 parataxis os,exhibited
R1247 T2471 T2472 compound Figure,1A
R1248 T2472 T2470 dep 1A,os
R1249 T2473 T2470 punct ", ",os
R1250 T2474 T2470 punct ),os
R1251 T2475 T2451 punct ", ",were
R1252 T2476 T2477 nmod Crx,retinas
R1253 T2477 T2451 nsubj retinas,were
R1254 T2478 T2476 punct -,Crx
R1255 T2479 T2476 punct /,Crx
R1256 T2480 T2476 punct -,Crx
R1257 T2481 T2451 prep without,were
R1258 T2482 T2483 det a,layer
R1259 T2483 T2481 pobj layer,without
R1260 T2484 T2483 amod recognizable,layer
R1261 T2485 T2486 amod outer,segment
R1262 T2486 T2483 compound segment,layer
R1263 T2487 T2488 punct (,Figure
R1264 T2488 T2451 parataxis Figure,were
R1265 T2489 T2488 nummod 1B,Figure
R1266 T2490 T2488 punct ),Figure
R1267 T2491 T2451 punct .,were
R1268 T2493 T2494 nmod Crx,photoreceptors
R1269 T2494 T2498 nsubj photoreceptors,had
R1270 T2495 T2493 punct -,Crx
R1271 T2496 T2493 punct /,Crx
R1272 T2497 T2493 punct -,Crx
R1273 T2499 T2500 amod inner,segments
R1274 T2500 T2498 dobj segments,had
R1275 T2501 T2498 punct ", ",had
R1276 T2502 T2498 advcl demonstrating,had
R1277 T2503 T2504 advmod at,least
R1278 T2504 T2505 advmod least,limited
R1279 T2505 T2506 amod limited,polarization
R1280 T2506 T2502 dobj polarization,demonstrating
R1281 T2507 T2506 compound photoreceptor,polarization
R1282 T2508 T2506 prep in,polarization
R1283 T2509 T2510 det the,mutant
R1284 T2510 T2508 pobj mutant,in
R1285 T2511 T2510 compound Crx,mutant
R1286 T2512 T2498 punct ", ",had
R1287 T2513 T2498 cc but,had
R1288 T2514 T2515 det the,segments
R1289 T2515 T2517 nsubj segments,were
R1290 T2516 T2515 amod inner,segments
R1291 T2517 T2498 conj were,had
R1292 T2518 T2519 advmod extremely,short
R1293 T2519 T2517 acomp short,were
R1294 T2520 T2521 punct (,Figure
R1295 T2521 T2517 parataxis Figure,were
R1296 T2522 T2521 nummod 2,Figure
R1297 T2523 T2521 punct ),Figure
R1298 T2524 T2517 punct .,were
R1299 T2526 T2527 advmod Furthermore,showed
R1300 T2528 T2527 punct ", ",showed
R1301 T2529 T2530 det the,majority
R1302 T2530 T2527 nsubj majority,showed
R1303 T2531 T2530 prep of,majority
R1304 T2532 T2533 amod inner,segments
R1305 T2533 T2531 pobj segments,of
R1306 T2534 T2535 det some,differentiation
R1307 T2535 T2527 dobj differentiation,showed
R1308 T2536 T2535 amod morphological,differentiation
R1309 T2537 T2527 punct ", ",showed
R1310 T2538 T2527 advcl having,showed
R1311 T2539 T2540 advmod approximately,many
R1312 T2540 T2542 amod many,mitochondria
R1313 T2541 T2540 advmod as,many
R1314 T2542 T2538 dobj mitochondria,having
R1315 T2543 T2542 prep as,mitochondria
R1316 T2544 T2545 det the,control
R1317 T2545 T2543 pobj control,as
R1318 T2546 T2547 punct (,1
R1319 T2547 T2538 parataxis 1,having
R1320 T2548 T2547 nmod Figure,1
R1321 T2549 T2547 cc and,1
R1322 T2550 T2547 conj 2,1
R1323 T2551 T2547 punct ),1
R1324 T2552 T2527 punct .,showed
R1325 T2554 T2555 advmod Occasionally,noted
R1326 T2556 T2555 punct ", ",noted
R1327 T2557 T2558 det an,segment
R1328 T2558 T2555 nsubjpass segment,noted
R1329 T2559 T2558 amod inner,segment
R1330 T2560 T2558 acl undergoing,segment
R1331 T2561 T2560 dobj lysis,undergoing
R1332 T2562 T2555 auxpass was,noted
R1333 T2563 T2555 punct ", ",noted
R1334 T2564 T2555 advcl appearing,noted
R1335 T2565 T2564 oprd swollen,appearing
R1336 T2566 T2565 cc or,swollen
R1337 T2567 T2565 conj with,swollen
R1338 T2568 T2567 pobj vacuoles,with
R1339 T2569 T2568 cc and,vacuoles
R1340 T2570 T2571 amod swollen,mitochondria
R1341 T2571 T2568 conj mitochondria,vacuoles
R1342 T2572 T2573 punct (,shown
R1343 T2573 T2564 parataxis shown,appearing
R1344 T2574 T2573 nsubj data,shown
R1345 T2575 T2573 neg not,shown
R1346 T2576 T2573 punct ),shown
R1347 T2577 T2555 punct .,noted
R1389 T2654 T2638 auxpass were,noted
R1390 T2655 T2656 punct (,3A
R1391 T2656 T2638 parataxis 3A,noted
R1392 T2657 T2656 nmod Figure,3A
R1393 T2658 T2656 cc and,3A
R1394 T2659 T2656 conj 3B,3A
R1395 T2660 T2656 punct ),3A
R1396 T2661 T2638 punct .,noted
R1397 T2663 T2664 advmod Sporadically,contained
R1398 T2665 T2664 punct ", ",contained
R1399 T2666 T2667 amod connecting,cilia
R1400 T2667 T2664 nsubj cilia,contained
R1401 T2668 T2664 dobj other,contained
R1402 T2669 T2668 prep than,other
R1403 T2670 T2671 det the,complement
R1404 T2671 T2669 pobj complement,than
R1405 T2672 T2671 amod typical,complement
R1406 T2673 T2671 prep of,complement
R1407 T2674 T2675 compound microtubule,doublets
R1408 T2675 T2673 pobj doublets,of
R1409 T2676 T2664 punct .,contained
R1410 T2678 T2679 prep For,shows
R1411 T2680 T2678 pobj example,For
R1412 T2681 T2679 punct ", ",shows
R1413 T2682 T2679 prep in,shows
R1414 T2683 T2684 compound Figure,3A
R1415 T2684 T2682 pobj 3A,in
R1416 T2685 T2679 punct ", ",shows
R1417 T2686 T2687 det the,cilium
R1418 T2687 T2679 nsubj cilium,shows
R1419 T2688 T2687 amod connecting,cilium
R1420 T2689 T2687 acl labelled,cilium
R1421 T2690 T2689 agent by,labelled
R1422 T2691 T2690 pobj arrowhead,by
R1423 T2692 T2691 nummod 1,arrowhead
R1424 T2693 T2679 punct ", ",shows
R1425 T2694 T2695 nummod 7,0
R1426 T2695 T2697 nummod 0,doublets
R1427 T2696 T2695 punct +,0
R1428 T2697 T2679 dobj doublets,shows
R1429 T2698 T2679 punct .,shows
R1430 T2700 T2701 det The,majority
R1431 T2701 T2702 nsubj majority,exhibited
R1432 T2703 T2704 det the,doublets
R1433 T2704 T2702 dobj doublets,exhibited
R1434 T2705 T2704 amod characteristic,doublets
R1435 T2706 T2707 nummod 9,0
R1436 T2707 T2704 nummod 0,doublets
R1437 T2708 T2707 punct +,0
R1438 T2709 T2710 punct (,2
R1439 T2710 T2702 parataxis 2,exhibited
R1440 T2711 T2710 nmod arrowhead,2
R1441 T2712 T2710 cc and,2
R1442 T2713 T2710 conj 3,2
R1443 T2714 T2710 prep in,2
R1444 T2715 T2716 compound Figure,3A
R1445 T2716 T2714 pobj 3A,in
R1446 T2717 T2716 cc and,3A
R1447 T2718 T2719 compound Figure,3B
R1448 T2719 T2716 conj 3B,3A
R1449 T2720 T2710 punct ),2
R1450 T2721 T2702 punct .,exhibited
R1451 T2723 T2724 det These,observations
R1452 T2724 T2725 nsubj observations,indicate
R1453 T2726 T2727 mark that,is
R1454 T2727 T2725 ccomp is,indicate
R1455 T2728 T2727 prep in,is
R1456 T2729 T2728 pobj addition,in
R1457 T2730 T2729 prep to,addition
R1458 T2731 T2732 amod inner,segment
R1459 T2732 T2733 compound segment,formation
R1460 T2733 T2730 pobj formation,to
R1461 T2734 T2727 punct ", ",is
R1462 T2735 T2727 nsubj ciliogenesis,is
R1463 T2736 T2727 advmod also,is
R1464 T2737 T2738 advmod largely,intact
R1465 T2738 T2727 acomp intact,is
R1466 T2739 T2727 prep in,is
R1467 T2740 T2741 nmod Crx,photoreceptors
R1469 T2742 T2740 punct -,Crx
R1470 T2743 T2740 punct /,Crx
R1542 T2848 T2849 punct (,mx
R1543 T2849 T2837 parataxis mx,noted
R1544 T2850 T2851 compound Figure,3A
R1545 T2851 T2849 dep 3A,mx
R1546 T2852 T2849 punct ", ",mx
R1547 T2853 T2849 punct ),mx
R1548 T2854 T2837 punct .,noted
R1549 T2856 T2857 advmod Second,found
R1550 T2858 T2857 punct ", ",found
R1551 T2859 T2860 advmod sporadically,displaced
R1552 T2860 T2861 amod displaced,nuclei
R1553 T2861 T2857 nsubjpass nuclei,found
R1554 T2862 T2857 auxpass were,found
R1555 T2863 T2857 advcl residing,found
R1556 T2864 T2863 prep in,residing
R1557 T2865 T2866 det the,space
R1558 T2866 T2864 pobj space,in
R1559 T2867 T2866 acl abutting,space
R1560 T2868 T2869 det the,PE
R1561 T2869 T2867 dobj PE,abutting
R1562 T2870 T2857 punct .,found
R1563 T2872 T2873 advmod Occasionally,appeared
R1564 T2874 T2873 punct ", ",appeared
R1565 T2875 T2876 det these,nuclei
R1566 T2876 T2873 nsubj nuclei,appeared
R1567 T2877 T2873 oprd pyknotic,appeared
R1568 T2878 T2879 punct (,n
R1569 T2879 T2873 parataxis n,appeared
R1570 T2880 T2881 compound Figure,3A
R1571 T2881 T2879 dep 3A,n
R1572 T2882 T2879 punct ", ",n
R1573 T2883 T2879 punct ),n
R1574 T2884 T2873 punct ;,appeared
R1575 T2885 T2873 cc but,appeared
R1576 T2886 T2873 punct ", ",appeared
R1577 T2887 T2888 advmod more,frequently
R1578 T2888 T2889 advmod frequently,exhibited
R1579 T2889 T2873 conj exhibited,appeared
R1580 T2890 T2891 det the,pattern
R1581 T2891 T2889 dobj pattern,exhibited
R1582 T2892 T2891 compound heterochromatin,pattern
R1583 T2893 T2891 amod typical,pattern
R1584 T2894 T2893 prep of,typical
R1585 T2895 T2894 pobj photoreceptors,of
R1586 T2896 T2897 punct (,shown
R1587 T2897 T2889 parataxis shown,exhibited
R1588 T2898 T2897 nsubj data,shown
R1589 T2899 T2897 neg not,shown
R1590 T2900 T2897 punct ),shown
R1591 T2901 T2889 punct ", ",exhibited
R1592 T2902 T2903 advmod strongly,suggesting
R1593 T2903 T2889 advcl suggesting,exhibited
R1594 T2904 T2905 mark that,belonged
R1595 T2905 T2903 ccomp belonged,suggesting
R1596 T2906 T2905 nsubj they,belonged
R1597 T2907 T2905 prep to,belonged
R1598 T2908 T2909 amod ectopic,photoreceptors
R1599 T2909 T2907 pobj photoreceptors,to
R1600 T2910 T2873 punct .,appeared
R1601 T2912 T2913 det The,entity
R1602 T2913 T2916 nsubj entity,were
R1603 T2914 T2913 amod third,entity
R1604 T2915 T2913 amod pathological,entity
R1605 T2917 T2913 acl noted,entity
R1606 T2918 T2917 prep in,noted
R1607 T2919 T2920 det the,layer
R1608 T2920 T2918 pobj layer,in
R1609 T2921 T2922 amod outer,segment
R1610 T2922 T2920 compound segment,layer
R1611 T2923 T2924 amod numerous,vesicles
R1612 T2924 T2916 attr vesicles,were
R1613 T2925 T2924 amod small,vesicles
R1614 T2926 T2927 punct (,arrow
R1615 T2927 T2924 parataxis arrow,vesicles
R1616 T2928 T2929 compound Figure,3A
R1617 T2929 T2927 compound 3A,arrow
R1618 T2930 T2927 punct ),arrow
R1619 T2931 T2932 quantmod 100,200
R1620 T2932 T2934 nummod 200,nm
R1621 T2933 T2932 quantmod to,200
R1622 T2934 T2924 appos nm,vesicles
R1623 T2935 T2934 prep in,nm
R1624 T2936 T2935 pobj diameter,in
R1625 T2937 T2916 punct .,were
R1626 T2939 T2940 nsubj They,appeared
R1627 T2941 T2942 aux to,emerging
R1628 T2942 T2940 xcomp emerging,appeared
R1629 T2943 T2942 aux be,emerging
R1630 T2944 T2942 prep from,emerging
R1631 T2945 T2946 det the,segments
R1632 T2946 T2944 pobj segments,from
R1633 T2947 T2946 amod inner,segments
R1634 T2948 T2940 punct ", ",appeared
R1635 T2949 T2950 mark as,showed
R1636 T2950 T2940 advcl showed,appeared
R1637 T2951 T2952 amod scanning,electron
R1638 T2952 T2953 npadvmod electron,microscopic
R1639 T2953 T2954 amod microscopic,images
R1640 T2954 T2950 nsubj images,showed
R1641 T2955 T2956 amod spherical,structures
R1642 T2956 T2950 dobj structures,showed
R1643 T2957 T2956 acl budding,structures
R1644 T2958 T2957 prep from,budding
R1645 T2959 T2960 det the,segments
R1646 T2960 T2958 pobj segments,from
R1647 T2961 T2960 amod inner,segments
R1648 T2962 T2963 punct (,arrow
R1649 T2963 T2950 parataxis arrow,showed
R1650 T2964 T2965 compound Figure,3C
R1651 T2965 T2963 dep 3C,arrow
R1652 T2966 T2963 punct ", ",arrow
R1653 T2967 T2963 punct ),arrow
R1654 T2968 T2940 punct .,appeared
R1655 T2970 T2971 prep In,viewed
R1656 T2972 T2970 pobj order,In
R1657 T2973 T2974 aux to,characterize
R1658 T2974 T2972 acl characterize,order
R1659 T2975 T2974 advmod further,characterize
R1660 T2976 T2977 det the,morphogenesis
R1661 T2977 T2974 dobj morphogenesis,characterize
R1662 T2978 T2977 prep of,morphogenesis
R1663 T2979 T2980 nmod Crx,photoreceptors
R1664 T2980 T2978 pobj photoreceptors,of
R1665 T2981 T2979 punct -,Crx
R1666 T2982 T2979 punct /,Crx
R1667 T2983 T2979 punct -,Crx
R1668 T2984 T2971 punct ", ",viewed
R1669 T2985 T2986 det the,layer
R1670 T2986 T2971 nsubjpass layer,viewed
R1671 T2987 T2986 amod developing,layer
R1672 T2988 T2989 amod outer,segment
R1673 T2989 T2986 compound segment,layer
R1674 T2990 T2971 auxpass was,viewed
R1675 T2991 T2971 prep by,viewed
R1676 T2992 T2993 amod scanning,microscopy
R1677 T2993 T2991 pobj microscopy,by
R1678 T2994 T2993 compound electron,microscopy
R1679 T2995 T2971 prep at,viewed
R1680 T2996 T2995 pobj P7,at
R1681 T2997 T2996 punct ", ",P7
R1682 T2998 T2996 conj P14,P7
R1683 T2999 T2998 cc and,P14
R1684 T3000 T2998 conj P21,P14
R1685 T3001 T3002 punct (,Figure
R1686 T3002 T2971 parataxis Figure,viewed
R1687 T3003 T3002 nummod 4,Figure
R1688 T3004 T3002 punct ),Figure
R1689 T3005 T2971 punct .,viewed
R1690 T3007 T3008 prep In,noted
R1691 T3009 T3010 nmod Crx,retinas
R1692 T3010 T3007 pobj retinas,In
R1693 T3011 T3009 punct +,Crx
R1694 T3012 T3009 punct /,Crx
R1695 T3013 T3009 punct +,Crx
R1696 T3014 T3008 punct ", ",noted
R1697 T3015 T3016 nmod photoreceptor,segments
R1698 T3016 T3008 nsubjpass segments,noted
R1699 T3017 T3016 amod inner,segments
R1700 T3018 T3016 punct ", ",segments
R1701 T3019 T3020 amod connecting,cilia
R1702 T3020 T3016 conj cilia,segments
R1703 T3021 T3020 punct ", ",cilia
R1704 T3022 T3020 cc and,cilia
R1705 T3023 T3024 det the,structures
R1706 T3024 T3020 conj structures,cilia
R1707 T3025 T3024 amod first,structures
R1708 T3026 T3024 amod rudimentary,structures
R1709 T3027 T3028 amod outer,segment
R1710 T3028 T3024 compound segment,structures
R1711 T3029 T3008 auxpass were,noted
R1712 T3030 T3008 prep at,noted
R1713 T3031 T3030 pobj P7,at
R1714 T3032 T3008 punct .,noted
R1715 T3034 T3035 prep In,emerging
R1716 T3036 T3037 det the,retina
R1717 T3037 T3034 pobj retina,In
R1718 T3038 T3037 nmod Crx,retina
R1719 T3039 T3038 punct -,Crx
R1720 T3040 T3038 punct /,Crx
R1721 T3041 T3038 punct -,Crx
R1722 T3042 T3035 punct ", ",emerging
R1723 T3043 T3044 advmod only,cilium
R1724 T3044 T3035 nsubjpass cilium,emerging
R1725 T3045 T3044 det an,cilium
R1726 T3046 T3044 amod occassional,cilium
R1727 T3047 T3044 amod connecting,cilium
R1728 T3048 T3035 auxpass was,emerging
R1729 T3049 T3035 aux noted,emerging
R1730 T3050 T3035 prep from,emerging
R1731 T3051 T3052 amod inner,segments
R1732 T3052 T3050 pobj segments,from
R1733 T3053 T3035 prep at,emerging
R1734 T3054 T3055 det this,stage
R1735 T3055 T3053 pobj stage,at
R1736 T3056 T3057 punct (,4A
R1737 T3057 T3035 parataxis 4A,emerging
R1738 T3058 T3057 compound Figure,4A
R1739 T3059 T3057 cc and,4A
R1740 T3060 T3057 conj 4B,4A
R1741 T3061 T3057 punct ),4A
R1742 T3062 T3035 punct .,emerging
R1743 T3064 T3065 det This,observation
R1744 T3065 T3066 nsubjpass observation,confirmed
R1745 T3067 T3066 auxpass was,confirmed
R1746 T3068 T3066 prep by,confirmed
R1747 T3069 T3068 pobj comparison,by
R1748 T3070 T3069 prep with,comparison
R1749 T3071 T3072 compound transmission,micrographs
R1750 T3072 T3070 pobj micrographs,with
R1751 T3073 T3072 compound electron,micrographs
R1752 T3074 T3075 punct (,Figure
R1753 T3075 T3066 parataxis Figure,confirmed
R1754 T3076 T3075 nummod 5,Figure
R1755 T3077 T3075 punct ),Figure
R1756 T3078 T3066 punct .,confirmed
R1757 T3080 T3081 det These,differences
R1758 T3081 T3082 nsubj differences,are
R1759 T3083 T3084 det the,differences
R1760 T3084 T3082 attr differences,are
R1761 T3085 T3084 amod earliest,differences
R1762 T3086 T3084 amod noted,differences
R1763 T3087 T3084 prep between,differences
R1764 T3088 T3089 nmod Crx,photoreceptors
R1765 T3089 T3087 pobj photoreceptors,between
R1766 T3090 T3088 punct +,Crx
R1767 T3091 T3088 punct /,Crx
R1768 T3092 T3088 punct +,Crx
R1769 T3093 T3088 cc and,Crx
R1770 T3094 T3088 conj Crx,Crx
R1771 T3095 T3094 punct -,Crx
R1772 T3096 T3094 punct /,Crx
R1773 T3097 T3094 punct -,Crx
R1774 T3098 T3082 punct .,are
R1775 T3100 T3101 prep At,noted
R1776 T3102 T3100 pobj P14,At
R1777 T3103 T3101 punct ", ",noted
R1778 T3104 T3105 amod elongating,segments
R1779 T3105 T3101 nsubjpass segments,noted
R1780 T3106 T3105 amod outer,segments
R1781 T3107 T3101 auxpass were,noted
R1782 T3108 T3101 prep on,noted
R1783 T3109 T3110 nmod Crx,photoreceptors
R1784 T3110 T3108 pobj photoreceptors,on
R1785 T3111 T3109 punct +,Crx
R1786 T3112 T3109 punct /,Crx
R1787 T3113 T3109 punct +,Crx
R1788 T3114 T3101 punct ", ",noted
R1789 T3115 T3116 advmod occasionally,demonstrating
R1790 T3116 T3101 advcl demonstrating,noted
R1791 T3117 T3118 det a,structure
R1792 T3118 T3116 dobj structure,demonstrating
R1793 T3119 T3120 npadvmod paddle,like
R1794 T3120 T3118 amod like,structure
R1795 T3121 T3120 punct -,like
R1796 T3122 T3116 prep at,demonstrating
R1797 T3123 T3124 poss their,apex
R1798 T3124 T3122 pobj apex,at
R1799 T3125 T3126 punct (,os
R1800 T3126 T3116 parataxis os,demonstrating
R1801 T3127 T3128 compound Figure,4C
R1802 T3128 T3126 dep 4C,os
R1803 T3129 T3126 punct ", ",os
R1804 T3130 T3126 punct ),os
R1805 T3131 T3101 punct .,noted
R1806 T3133 T3134 prep In,demonstrated
R1807 T3135 T3136 nmod Crx,retinae
R1808 T3136 T3133 pobj retinae,In
R1809 T3137 T3135 punct -,Crx
R1810 T3138 T3135 punct /,Crx
R1811 T3139 T3135 punct -,Crx
R1812 T3140 T3134 punct ", ",demonstrated
R1813 T3141 T3142 det the,majority
R1814 T3142 T3134 nsubj majority,demonstrated
R1815 T3143 T3142 amod vast,majority
R1816 T3144 T3142 prep of,majority
R1817 T3145 T3144 pobj photoreceptors,of
R1818 T3153 T3151 pobj segments,without
R1819 T3146 T3145 prep at,photoreceptors
R1820 T3154 T3155 punct (,cc
R1821 T3147 T3148 det this,stage
R1822 T3155 T3134 parataxis cc,demonstrated
R1823 T3156 T3157 compound Figure,4D
R1824 T3148 T3146 pobj stage,at
R1825 T3157 T3155 dep 4D,cc
R1826 T3158 T3155 punct ", ",cc
R1827 T3149 T3150 amod connecting,cilia
R1828 T3159 T3155 punct ),cc
R1829 T3160 T3134 punct .,demonstrated
R1830 T3150 T3134 dobj cilia,demonstrated
R1831 T3162 T3163 advmod Sporadically,exhibit
R1832 T3151 T3150 prep without,cilia
R1833 T3164 T3163 punct ", ",exhibit
R1834 T3165 T3166 nmod Crx,photoreceptors
R1835 T3166 T3163 nsubj photoreceptors,exhibit
R1836 T3152 T3153 amod outer,segments
R1837 T3167 T3165 punct -,Crx
R1838 T3168 T3165 punct /,Crx
R1839 T3258 T3259 compound Figure,4F
R1840 T3169 T3165 punct -,Crx
R1841 T3170 T3163 aux would,exhibit
R1842 T3171 T3172 det an,structure
R1843 T3259 T3257 dep 4F,cc
R1844 T3172 T3163 dobj structure,exhibit
R1845 T3173 T3172 amod irregular,structure
R1846 T3174 T3172 acl extending,structure
R1847 T3260 T3257 punct ", ",cc
R1848 T3175 T3174 prep from,extending
R1849 T3176 T3177 det a,cilium
R1850 T3177 T3175 pobj cilium,from
R1851 T3261 T3257 punct ),cc
R1852 T3178 T3177 amod connecting,cilium
R1853 T3179 T3180 punct (,cc*
R1854 T3262 T3242 punct .,noted
R1855 T3180 T3174 parataxis cc*,extending
R1856 T3181 T3182 compound Figure,4D
R1857 T3182 T3180 dep 4D,cc*
R1858 T3183 T3180 punct ", ",cc*
R1859 T3264 T3265 amod Serial,examination
R1860 T3184 T3180 punct ),cc*
R1861 T3185 T3186 advmod perhaps,representing
R1862 T3186 T3172 acl representing,structure
R1863 T3265 T3266 nsubj examination,demonstrated
R1864 T3187 T3188 det a,segment
R1865 T3188 T3186 dobj segment,representing
R1866 T3189 T3188 amod malformed,segment
R1867 T3190 T3188 amod outer,segment
R1868 T3191 T3163 punct .,exhibit
R1869 T3267 T3265 prep of,examination
R1870 T3193 T3194 amod Such,structures
R1871 T3194 T3195 nsubjpass structures,observed
R1872 T3196 T3195 auxpass were,observed
R1873 T3197 T3195 dobj also,observed
R1874 T3268 T3269 nmod Crx,photoreceptors
R1875 T3198 T3195 prep at,observed
R1876 T3199 T3198 pobj P21,at
R1877 T3269 T3267 pobj photoreceptors,of
R1878 T3200 T3201 punct (,cc*
R1879 T3201 T3195 parataxis cc*,observed
R1880 T3202 T3203 compound Figure,4F
R1881 T3270 T3268 punct -,Crx
R1882 T3203 T3201 dep 4F,cc*
R1883 T3204 T3201 punct ", ",cc*
R1884 T3205 T3201 punct ),cc*
R1885 T3271 T3268 punct /,Crx
R1886 T3206 T3195 punct .,observed
R1887 T3272 T3268 punct -,Crx
R1888 T3208 T3209 det These,segments
R1889 T3209 T3214 nsubjpass segments,noted
R1890 T3210 T3209 amod putative,segments
R1891 T3273 T3265 prep at,examination
R1892 T3211 T3209 punct ", ",segments
R1893 T3212 T3209 amod abnormal,segments
R1894 T3213 T3209 amod outer,segments
R1895 T3274 T3273 pobj P7,at
R1896 T3215 T3214 auxpass were,noted
R1897 T3216 T3217 advmod only,rarely
R1898 T3275 T3274 punct ", ",P7
R1899 T3217 T3214 advmod rarely,noted
R1900 T3276 T3274 conj P10,P7
R1901 T3277 T3276 punct ", ",P10
R1902 T3218 T3214 prep in,noted
R1903 T3219 T3218 pobj Crx,in
R1904 T3278 T3276 conj P14,P10
R1905 T3220 T3219 punct +,Crx
R1906 T3221 T3219 punct /,Crx
R1907 T3222 T3219 punct +,Crx
R1908 T3279 T3278 punct ", ",P14
R1909 T3280 T3278 cc and,P14
R1910 T3223 T3214 prep at,noted
R1911 T3224 T3223 pobj P14,at
R1912 T3281 T3278 conj P21,P14
R1913 T3225 T3214 punct ", ",noted
R1914 T3226 T3214 cc and,noted
R1915 T3282 T3265 prep by,examination
R1916 T3227 T3214 conj never,noted
R1917 T3228 T3227 prep at,never
R1918 T3229 T3228 pobj P21,at
R1919 T3230 T3231 punct (,cc
R1920 T3231 T3227 parataxis cc,never
R1921 T3283 T3282 pobj TEM,by
R1922 T3232 T3233 compound Figure,4C
R1923 T3233 T3231 dep 4C,cc
R1924 T3234 T3233 cc and,4C
R1925 T3284 T3266 punct ", ",demonstrated
R1926 T3235 T3233 conj 4E,4C
R1927 T3236 T3231 punct ", ",cc
R1928 T3237 T3231 punct *,cc
R1929 T3285 T3286 det a,lack
R1930 T3238 T3231 punct ),cc
R1931 T3239 T3214 punct .,noted
R1932 T3286 T3266 dobj lack,demonstrated
R1933 T3241 T3242 advmod Further,noted
R1934 T3243 T3242 punct ", ",noted
R1935 T3287 T3286 amod distinctive,lack
R1936 T3244 T3242 prep in,noted
R1937 T3245 T3246 nmod Crx,photoreceptors
R1938 T3246 T3244 pobj photoreceptors,in
R1939 T3288 T3286 prep of,lack
R1940 T3247 T3245 punct -,Crx
R1941 T3248 T3245 punct /,Crx
R1942 T3249 T3245 punct -,Crx
R1943 T3289 T3290 det any,structure
R1944 T3250 T3242 punct ", ",noted
R1945 T3251 T3252 advmod unusually,long
R1946 T3290 T3288 pobj structure,of
R1947 T3252 T3253 amod long,cilia
R1948 T3253 T3242 nsubjpass cilia,noted
R1949 T3254 T3253 amod connecting,cilia
R1950 T3291 T3290 amod interpretable,structure
R1951 T3255 T3242 auxpass were,noted
R1952 T3256 T3257 punct (,cc
R1953 T3257 T3242 parataxis cc,noted
R1954 T3292 T3291 prep as,interpretable
R1955 T3293 T3294 amod orderly,stacks
R1956 T3294 T3292 pobj stacks,as
R1957 T3295 T3294 prep of,stacks
R1958 T3296 T3295 pobj discs,of
R1959 T3297 T3296 cc or,discs
R1960 T3298 T3299 amod forming,discs
R1961 T3299 T3296 conj discs,discs
R1962 T3300 T3266 punct .,demonstrated
R1963 T3302 T3303 det These,data
R1965 T3303 T3304 nsubj data,demonstrate
R1966 T3305 T3306 det a,absence
R1967 T3306 T3304 dobj absence,demonstrate
R1968 T3307 T3306 amod complete,absence
R1969 T3308 T3306 prep of,absence
R1970 T3309 T3310 amod normal,formation
R1988 T3377 T3375 pobj photoreceptors,to
R1990 T3378 T3376 punct -,rhodopsin
R1991 T3379 T3376 punct /,rhodopsin
R1992 T3380 T3376 punct -,rhodopsin
R1994 T3381 T3376 cc and,rhodopsin
R1995 T3382 T3376 conj peripherin,rhodopsin
R1996 T3383 T3382 punct -,peripherin
R1998 T3384 T3382 punct /,peripherin
R1999 T3385 T3382 punct -,peripherin
R2000 T3386 T3365 punct .,compared
R2005 T3388 T3389 nsubj Rhodopsin,are
R2006 T3390 T3388 cc and,Rhodopsin
R2008 T3391 T3388 conj peripherin,Rhodopsin
R2009 T3392 T3393 nummod two,genes
R2011 T3393 T3389 attr genes,are
R2012 T3394 T3395 npadvmod photoreceptor,specific
R2013 T3395 T3393 amod specific,genes
R2015 T3396 T3395 punct -,specific
R2016 T3397 T3398 poss whose,expression
R2017 T3398 T3399 dep expression,downregulated
R2019 T3399 T3393 relcl downregulated,genes
R2020 T3400 T3399 auxpass is,downregulated
R2021 T3401 T3399 advmod significantly,downregulated
R2023 T3402 T3399 prep in,downregulated
R2024 T3403 T3404 det the,retinae
R2025 T3404 T3402 pobj retinae,in
R2026 T3405 T3404 nmod Crx,retinae
R2027 T3406 T3405 punct -,Crx
R2029 T3407 T3405 punct /,Crx
R2030 T3408 T3405 punct -,Crx
R2031 T3409 T3410 punct [,35
R2032 T3410 T3399 parataxis 35,downregulated
R2034 T3411 T3410 nummod 10,35
R2035 T3412 T3410 punct ",",35
R2037 T3413 T3410 nummod 34,35
R2038 T3414 T3410 punct ",",35
R2039 T3415 T3410 punct ],35
R2041 T3416 T3389 punct .,are
R2043 T3418 T3419 nmod Loss,mutations
R2044 T3419 T3422 nsubjpass mutations,reported
R2045 T3420 T3418 prep of,Loss
R2047 T3421 T3420 pobj function,of
R2048 T3423 T3419 prep in,mutations
R2050 T3424 T3423 pobj each,in
R2051 T3425 T3424 prep of,each
R2052 T3426 T3427 det these,genes
R2054 T3427 T3425 pobj genes,of
R2055 T3428 T3422 advmod separately,reported
R2056 T3429 T3422 aux have,reported
R2057 T3430 T3422 auxpass been,reported
R2058 T3431 T3432 aux to,result
R2059 T3432 T3422 xcomp result,reported
R2060 T3433 T3432 prep in,result
R2061 T3434 T3435 det a,failure
R2062 T3435 T3433 pobj failure,in
R2063 T3436 T3437 aux to,elaborate
R2064 T3437 T3435 acl elaborate,failure
R2065 T3438 T3439 amod outer,segments
R2066 T3439 T3437 dobj segments,elaborate
R2067 T3440 T3441 punct [,30
R2068 T3441 T3422 parataxis 30,reported
R2069 T3442 T3441 nummod 29,30
R2070 T3443 T3441 punct ",",30
R2071 T3444 T3441 punct ],30
R2072 T3445 T3422 punct .,reported
R2073 T3447 T3448 nsubj Photoreceptors,appeared
R2074 T3449 T3447 prep from,Photoreceptors
R2075 T3450 T3451 det these,mice
R2076 T3451 T3449 pobj mice,from
R2077 T3452 T3451 nummod two,mice
R2078 T3453 T3451 amod mutant,mice
R2079 T3454 T3451 acl examined,mice
R2080 T3455 T3454 prep by,examined
R2081 T3456 T3455 pobj SEM,by
R2082 T3457 T3454 prep from,examined
R2083 T3458 T3459 det the,side
R2084 T3459 T3457 pobj side,from
R2085 T3460 T3459 amod scleral,side
R2086 T3461 T3462 advmod highly,similar
R2087 T3462 T3448 oprd similar,appeared
R2088 T3463 T3462 prep to,similar
R2089 T3464 T3465 nmod Crx,photoreceptors
R2090 T3465 T3463 pobj photoreceptors,to
R2091 T3466 T3464 punct -,Crx
R2092 T3467 T3464 punct /,Crx
R2093 T3468 T3464 punct -,Crx
R2094 T3469 T3470 punct (,compare
R2095 T3470 T3448 parataxis compare,appeared
R2096 T3471 T3472 compound Figure,4F
R2097 T3472 T3470 dobj 4F,compare
R2098 T3473 T3470 prep to,compare
R2099 T3474 T3475 compound Figure,6A
R2100 T3475 T3473 pobj 6A,to
R2101 T3476 T3475 cc and,6A
R2102 T3477 T3475 conj 6B,6A
R2103 T3478 T3470 punct ),compare
R2104 T3479 T3448 punct .,appeared
R5061 T8250 T8251 compound Transmission,microscopy
R5062 T8252 T8251 compound electron,microscopy
R5063 T8253 T8251 prep of,microscopy
R5064 T8254 T8255 det the,retina
R5065 T8255 T8253 pobj retina,of
R5066 T8256 T8255 amod outer,retina
R5067 T8257 T8251 prep at,microscopy
R5068 T8258 T8257 pobj P21,at
R5069 T8259 T8251 prep in,microscopy
R5070 T8260 T8261 punct (,A
R5071 T8261 T8262 meta A,Crx
R5072 T8262 T8264 nmod Crx,retinas
R5073 T8263 T8261 punct ),A
R5074 T8264 T8259 pobj retinas,in
R5075 T8265 T8262 punct +,Crx
R5076 T8266 T8262 punct /,Crx
R5077 T8267 T8262 punct +,Crx
R5078 T8268 T8262 cc and,Crx
R5079 T8269 T8270 punct (,B
R5080 T8270 T8271 meta B,Crx
R5081 T8271 T8262 conj Crx,Crx
R5082 T8272 T8270 punct ),B
R5083 T8273 T8271 punct -,Crx
R5084 T8274 T8271 punct /,Crx
R5085 T8275 T8271 punct -,Crx
R5086 T8276 T8251 punct .,microscopy
R5087 T8279 T8278 punct ", ",pe
R5088 T8280 T8281 amod pigmented,epithelium
R5089 T8281 T8278 appos epithelium,pe
R5090 T8282 T8278 punct .,pe
R5091 T8285 T8284 punct ", ",os
R5092 T8286 T8287 amod outer,segments
R5093 T8287 T8284 appos segments,os
R5094 T8288 T8284 punct .,os
R5095 T8291 T8290 punct ", ",is
R5096 T8292 T8293 amod inner,segments
R5097 T8293 T8290 appos segments,is
R5098 T8294 T8290 punct .,is
R5099 T8297 T8296 punct ", ",onl
R5100 T8298 T8299 amod outer,layer
R5101 T8299 T8296 appos layer,onl
R5102 T8300 T8299 amod nuclear,layer
R5103 T8301 T8299 prep with,layer
R5104 T8302 T8303 compound photoreceptor,nuclei
R5105 T8303 T8301 pobj nuclei,with
R5106 T8304 T8296 punct .,onl
R5107 T8306 T8307 compound Scale,bar
R5108 T8307 T8308 nsubj bar,μm
R5109 T8309 T8308 punct =,μm
R5110 T8310 T8308 nummod 5,μm
R5111 T8311 T8308 prep for,μm
R5112 T8312 T8311 pobj A,for
R5113 T8313 T8312 cc and,A
R5114 T8314 T8312 conj B,A
R5115 T8315 T8308 punct .,μm
R5118 T8372 T8373 compound Transmission,micrograph
R5119 T8374 T8373 compound electron,micrograph
R5120 T8375 T8373 prep of,micrograph
R5121 T8376 T8377 det the,layer
R5122 T8377 T8375 pobj layer,of
R5123 T8378 T8379 amod outer,segment
R5124 T8379 T8377 compound segment,layer
R5125 T8380 T8377 prep of,layer
R5126 T8381 T8382 nmod Crx,retina
R5127 T8382 T8380 pobj retina,of
R5128 T8383 T8381 punct -,Crx
R5129 T8384 T8381 punct /,Crx
R5130 T8385 T8381 punct -,Crx
R5131 T8386 T8373 prep at,micrograph
R5132 T8387 T8386 pobj P21,at
R5133 T8388 T8373 punct .,micrograph
R5134 T8390 T8391 amod Inner,segments
R5135 T8391 T8392 nsubj segments,exhibit
R5136 T8393 T8391 prep of,segments
R5137 T8394 T8395 nmod Crx,photoreceptors
R5138 T8395 T8393 pobj photoreceptors,of
R5139 T8396 T8394 punct -,Crx
R5140 T8397 T8394 punct /,Crx
R5141 T8398 T8394 punct -,Crx
R5142 T8399 T8400 amod numerous,mitochondria
R5143 T8400 T8392 dobj mitochondria,exhibit
R5144 T8401 T8402 punct (,indicated
R5145 T8402 T8400 parataxis indicated,mitochondria
R5146 T8403 T8402 nsubj m,indicated
R5147 T8404 T8402 agent by,indicated
R5148 T8405 T8404 pobj arrow,by
R5149 T8406 T8402 punct ),indicated
R5150 T8407 T8392 prep as,exhibit
R5151 T8408 T8407 prep in,as
R5152 T8409 T8408 pobj Crx,in
R5153 T8410 T8409 punct +,Crx
R5154 T8411 T8409 punct /,Crx
R5155 T8412 T8409 punct +,Crx
R5156 T8413 T8414 punct (,Figure
R5157 T8414 T8392 parataxis Figure,exhibit
R5158 T8415 T8414 nummod 1A,Figure
R5159 T8416 T8414 punct ),Figure
R5160 T8417 T8392 punct .,exhibit
R5161 T8420 T8419 punct ", ",pe
R5162 T8421 T8422 amod pigmented,epithelium
R5163 T8422 T8419 appos epithelium,pe
R5164 T8423 T8419 punct .,pe
R5165 T8426 T8425 punct ", ",is
R5166 T8427 T8428 amod inner,segments
R5167 T8428 T8425 appos segments,is
R5168 T8429 T8425 punct .,is
R5169 T8432 T8431 punct ", ",onl
R5170 T8433 T8434 amod outer,layer
R5171 T8434 T8431 appos layer,onl
R5172 T8435 T8434 amod nuclear,layer
R5173 T8436 T8431 punct .,onl
R5174 T8438 T8439 compound Scale,bar
R5175 T8439 T8440 nsubj bar,μm
R5176 T8441 T8440 punct =,μm
R5177 T8442 T8440 nummod 2,μm
R5178 T8443 T8440 punct .,μm
R5181 T8570 T8571 compound Transmission,micrograph
R5182 T8572 T8571 compound electron,micrograph
R5183 T8573 T8571 prep of,micrograph
R5184 T8574 T8575 nmod Crx,retina
R5185 T8575 T8573 pobj retina,of
R5186 T8576 T8574 punct -,Crx
R5187 T8577 T8574 punct /,Crx
R5188 T8578 T8574 punct -,Crx
R5189 T8579 T8575 prep at,retina
R5190 T8580 T8579 pobj P21,at
R5191 T8581 T8582 punct (,A
R5192 T8582 T8571 parataxis A,micrograph
R5193 T8583 T8582 cc and,A
R5194 T8584 T8582 conj B,A
R5195 T8585 T8582 punct ),A
R5196 T8586 T8571 punct ", ",micrograph
R5197 T8587 T8571 cc and,micrograph
R5198 T8588 T8589 amod scanning,micrograph
R5199 T8589 T8571 conj micrograph,micrograph
R5200 T8590 T8589 compound electron,micrograph
R5201 T8591 T8589 prep of,micrograph
R5202 T8592 T8591 pobj Crx,of
R5203 T8593 T8592 punct -,Crx
R5204 T8594 T8592 punct /,Crx
R5205 T8595 T8592 punct -,Crx
R5206 T8596 T8592 prep at,Crx
R5207 T8597 T8596 pobj P10,at
R5208 T8598 T8599 punct (,C
R5209 T8599 T8589 parataxis C,micrograph
R5210 T8600 T8599 punct ),C
R5211 T8601 T8571 prep of,micrograph
R5212 T8602 T8603 amod outer,segment
R5213 T8603 T8604 compound segment,layer
R5214 T8604 T8601 pobj layer,of
R5215 T8605 T8571 punct .,micrograph
R5216 T8607 T8608 punct (,A
R5217 T8608 T8609 meta A,Evidence
R5218 T8610 T8608 punct ),A
R5219 T8611 T8609 prep of,Evidence
R5220 T8612 T8611 pobj ciliogenesis,of
R5221 T8613 T8609 prep in,Evidence
R5222 T8614 T8615 det the,layer
R5223 T8615 T8613 pobj layer,in
R5224 T8616 T8615 compound photoreceptor,layer
R5225 T8617 T8615 prep of,layer
R5226 T8618 T8619 nmod Crx,retina
R5227 T8619 T8617 pobj retina,of
R5228 T8620 T8618 punct -,Crx
R5229 T8621 T8618 punct /,Crx
R5230 T8622 T8618 punct -,Crx
R5231 T8623 T8609 punct .,Evidence
R5232 T8625 T8626 amod Nonmotile,cilia
R5233 T8626 T8628 nsubjpass cilia,observed
R5234 T8627 T8626 amod connecting,cilia
R5235 T8629 T8628 auxpass were,observed
R5236 T8630 T8628 prep in,observed
R5237 T8631 T8632 compound cross,section
R5238 T8632 T8630 pobj section,in
R5239 T8633 T8634 punct (,1
R5240 T8634 T8628 parataxis 1,observed
R5241 T8635 T8634 nmod arrowheads,1
R5242 T8636 T8634 punct ",",1
R5243 T8637 T8634 conj 2,1
R5244 T8638 T8637 punct ", ",2
R5245 T8639 T8637 cc and,2
R5246 T8640 T8637 conj 3,2
R5247 T8641 T8634 punct ", ",1
R5248 T8642 T8634 prep for,1
R5249 T8643 T8642 pobj examples,for
R5250 T8644 T8634 punct ),1
R5251 T8645 T8628 punct .,observed
R5252 T8647 T8648 amod Connecting,cilium
R5253 T8648 T8649 nsubj cilium,demonstrated
R5254 T8650 T8648 nummod 1,cilium
R5255 T8651 T8652 punct (,arrowhead
R5256 T8652 T8648 parataxis arrowhead,cilium
R5257 T8653 T8652 nummod 1,arrowhead
R5258 T8654 T8652 punct ),arrowhead
R5259 T8655 T8656 nummod seven,doublets
R5260 T8656 T8649 dobj doublets,demonstrated
R5261 T8657 T8656 amod microtuble,doublets
R5262 T8658 T8649 punct ", ",demonstrated
R5263 T8659 T8660 mark while,exhibited
R5264 T8660 T8649 advcl exhibited,demonstrated
R5265 T8661 T8660 nsubj cilium,exhibited
R5266 T8662 T8661 nummod 2,cilium
R5267 T8663 T8661 cc and,cilium
R5268 T8664 T8661 conj cilium,cilium
R5269 T8665 T8664 nummod 3,cilium
R5270 T8666 T8660 dobj nine,exhibited
R5271 T8667 T8649 punct .,demonstrated
R5272 T8669 T8670 prep In,seen
R5273 T8671 T8669 pobj A,In
R5274 T8672 T8670 punct ", ",seen
R5275 T8673 T8674 det a,nucleus
R5276 T8674 T8670 nsubjpass nucleus,seen
R5277 T8675 T8674 amod displaced,nucleus
R5278 T8676 T8674 compound cell,nucleus
R5279 T8677 T8674 punct (,nucleus
R5280 T8678 T8674 appos n,nucleus
R5281 T8679 T8674 punct ),nucleus
R5282 T8680 T8674 acl appearing,nucleus
R5283 T8681 T8680 oprd pyknotic,appearing
R5284 T8682 T8674 cc and,nucleus
R5285 T8683 T8684 amod abnormal,deposition
R5286 T8684 T8674 conj deposition,nucleus
R5287 T8685 T8684 prep of,deposition
R5288 T8686 T8687 nmod matrix,material
R5289 T8687 T8685 pobj material,of
R5290 T8688 T8686 punct (,matrix
R5291 T8689 T8686 appos mx,matrix
R5292 T8690 T8687 punct ),material
R5293 T8691 T8687 prep of,material
R5294 T8692 T8693 amod unknown,identity
R5295 T8693 T8691 pobj identity,of
R5296 T8694 T8670 auxpass were,seen
R5297 T8695 T8670 punct ", ",seen
R5298 T8696 T8670 prep along,seen
R5299 T8697 T8696 prep with,along
R5300 T8698 T8699 amod large,amounts
R5301 T8699 T8697 pobj amounts,with
R5302 T8700 T8699 prep of,amounts
R5303 T8701 T8702 amod membranous,vesicles
R5304 T8702 T8700 pobj vesicles,of
R5305 T8703 T8704 punct (,arrow
R5306 T8704 T8702 parataxis arrow,vesicles
R5307 T8705 T8704 punct ),arrow
R5308 T8706 T8707 dep which,filled
R5309 T8707 T8699 relcl filled,amounts
R5310 T8708 T8709 det the,space
R5311 T8709 T8707 dobj space,filled
R5312 T8710 T8709 compound photoreceptor,space
R5313 T8711 T8707 cc and,filled
R5314 T8712 T8707 conj appeared,filled
R5315 T8713 T8714 aux to,released
R5316 T8714 T8712 xcomp released,appeared
R5317 T8715 T8714 auxpass be,released
R5318 T8716 T8714 prep from,released
R5319 T8717 T8718 amod inner,segments
R5320 T8718 T8716 pobj segments,from
R5321 T8719 T8670 punct .,seen
R5322 T8721 T8722 compound Scale,bar
R5323 T8722 T8723 nsubj bar,μm
R5324 T8724 T8723 punct =,μm
R5325 T8725 T8723 nummod 3.7,μm
R5326 T8726 T8723 punct .,μm
R5327 T8728 T8729 punct (,B
R5328 T8729 T8730 meta B,cilium
R5329 T8731 T8729 punct ),B
R5330 T8732 T8730 amod Nonmotile,cilium
R5331 T8733 T8730 amod connecting,cilium
R5332 T8734 T8730 prep in,cilium
R5333 T8735 T8736 compound cross,section
R5334 T8736 T8734 pobj section,in
R5335 T8737 T8730 punct ", ",cilium
R5336 T8738 T8730 prep from,cilium
R5337 T8739 T8740 det a,photoreceptor
R5338 T8740 T8738 pobj photoreceptor,from
R5339 T8741 T8740 nmod Crx,photoreceptor
R5340 T8742 T8741 punct -,Crx
R5341 T8743 T8741 punct /,Crx
R5342 T8744 T8741 punct -,Crx
R5343 T8745 T8730 punct ", ",cilium
R5344 T8746 T8730 acl demonstrating,cilium
R5345 T8747 T8748 amod characteristic,array
R5346 T8748 T8746 dobj array,demonstrating
R5347 T8749 T8750 nummod 9,0
R5348 T8750 T8748 nummod 0,array
R5349 T8751 T8750 punct +,0
R5350 T8752 T8748 amod radial,array
R5351 T8753 T8748 prep of,array
R5352 T8754 T8755 compound microtubule,doublets
R5353 T8755 T8753 pobj doublets,of
R5354 T8756 T8730 punct .,cilium
R5355 T8758 T8759 compound Scale,bar
R5356 T8759 T8760 nsubj bar,nm
R5357 T8761 T8760 punct =,nm
R5358 T8762 T8760 nummod 88,nm
R5359 T8763 T8760 punct .,nm
R5360 T8765 T8766 punct (,C
R5361 T8766 T8767 meta C,micrograph
R5362 T8768 T8766 punct ),C
R5363 T8769 T8767 amod Scanning,micrograph
R5364 T8770 T8767 compound electron,micrograph
R5365 T8771 T8772 punct (,SEM
R5366 T8772 T8767 appos SEM,micrograph
R5367 T8773 T8767 punct ),micrograph
R5368 T8774 T8767 prep of,micrograph
R5369 T8775 T8776 amod membranous,vesicles
R5370 T8776 T8774 pobj vesicles,of
R5371 T8777 T8778 punct (,shows
R5372 T8778 T8776 parataxis shows,vesicles
R5373 T8779 T8778 nsubj arrow,shows
R5374 T8780 T8781 nummod one,example
R5375 T8781 T8778 dobj example,shows
R5376 T8782 T8778 punct ),shows
R5377 T8783 T8776 acl shed,vesicles
R5378 T8784 T8783 prep from,shed
R5379 T8785 T8786 amod inner,segments
R5380 T8786 T8784 pobj segments,from
R5381 T8787 T8786 prep of,segments
R5382 T8788 T8789 nmod Crx,photoreceptors
R5383 T8789 T8787 pobj photoreceptors,of
R5384 T8790 T8788 punct -,Crx
R5385 T8791 T8788 punct /,Crx
R5386 T8792 T8788 punct -,Crx
R5387 T8793 T8783 prep at,shed
R5388 T8794 T8793 pobj P10,at
R5389 T8795 T8767 punct .,micrograph
R5390 T8797 T8798 nsubj Figure,shows
R5391 T8799 T8800 amod inner,segments
R5392 T8800 T8798 dobj segments,shows
R5393 T8801 T8800 acl viewed,segments
R5394 T8802 T8801 prep from,viewed
R5395 T8803 T8804 det the,side
R5396 T8804 T8802 pobj side,from
R5397 T8805 T8804 amod scleral,side
R5398 T8806 T8807 mark with,removed
R5399 T8807 T8798 advcl removed,shows
R5400 T8808 T8809 det the,epithelium
R5401 T8809 T8807 nsubj epithelium,removed
R5402 T8810 T8809 amod pigmented,epithelium
R5403 T8811 T8798 punct .,shows
R5404 T8813 T8814 compound Scale,bar
R5405 T8814 T8815 nsubj bar,μm
R5406 T8816 T8815 punct =,μm
R5407 T8817 T8815 nummod 1,μm
R5408 T8818 T8815 punct .,μm
R5409 T8923 T8924 compound Outer,segment
R5410 T8924 T8925 compound segment,morphogenesis
R5411 T8926 T8925 prep in,morphogenesis
R5412 T8927 T8928 nmod Crx,photoreceptors
R5413 T8928 T8926 pobj photoreceptors,in
R5414 T8929 T8927 punct -,Crx
R5415 T8930 T8927 punct /,Crx
R5416 T8931 T8927 punct -,Crx
R5417 T8932 T8925 punct .,morphogenesis
R5418 T8934 T8935 amod Scanning,microscopy
R5419 T8936 T8935 compound electron,microscopy
R5420 T8937 T8935 prep of,microscopy
R5421 T8938 T8939 amod developing,photoreceptors
R5422 T8939 T8937 pobj photoreceptors,of
R5423 T8940 T8939 acl viewed,photoreceptors
R5424 T8941 T8940 prep from,viewed
R5425 T8942 T8943 det the,side
R5426 T8943 T8941 pobj side,from
R5427 T8944 T8943 amod scleral,side
R5428 T8945 T8946 mark with,removed
R5429 T8946 T8940 advcl removed,viewed
R5430 T8947 T8948 det the,epithelium
R5431 T8948 T8946 nsubj epithelium,removed
R5432 T8949 T8948 amod pigmented,epithelium
R5433 T8950 T8946 prep at,removed
R5434 T8951 T8950 pobj P7,at
R5435 T8952 T8951 punct ", ",P7
R5436 T8953 T8951 conj P14,P7
R5437 T8954 T8953 punct ", ",P14
R5438 T8955 T8953 cc and,P14
R5439 T8956 T8953 conj P21,P14
R5440 T8957 T8946 prep for,removed
R5441 T8958 T8959 nmod Crx,littermates
R5442 T8959 T8957 pobj littermates,for
R5443 T8960 T8958 punct +,Crx
R5444 T8961 T8958 punct /,Crx
R5445 T8962 T8958 punct +,Crx
R5446 T8963 T8964 punct (,A
R5447 T8964 T8958 parataxis A,Crx
R5448 T8965 T8964 punct ", ",A
R5449 T8966 T8964 conj C,A
R5450 T8967 T8966 punct ", ",C
R5451 T8968 T8966 cc and,C
R5452 T8969 T8966 conj E,C
R5453 T8970 T8964 punct ),A
R5454 T8971 T8958 cc and,Crx
R5455 T8972 T8958 conj Crx,Crx
R5456 T8973 T8972 punct -,Crx
R5457 T8974 T8972 punct /,Crx
R5458 T8975 T8972 punct -,Crx
R5459 T8976 T8977 punct (,F
R5460 T8977 T8972 parataxis F,Crx
R5461 T8978 T8977 nmod B,F
R5462 T8979 T8977 punct ", ",F
R5463 T8980 T8977 nmod D,F
R5464 T8981 T8977 punct ", ",F
R5465 T8982 T8977 punct ),F
R5466 T8983 T8935 punct .,microscopy
R5467 T8985 T8986 prep In,were
R5468 T8987 T8988 nmod Crx,retina
R5469 T8988 T8985 pobj retina,In
R5470 T8989 T8987 punct +,Crx
R5471 T8990 T8987 punct /,Crx
R5472 T8991 T8987 punct +,Crx
R5473 T8992 T8986 punct ", ",were
R5474 T8993 T8994 amod numerous,cilia
R5475 T8994 T8986 nsubj cilia,were
R5476 T8995 T8994 amod connecting,cilia
R5477 T8996 T8997 punct (,cc
R5478 T8997 T8994 parataxis cc,cilia
R5479 T8998 T8997 dep A,cc
R5480 T8999 T8997 punct ", ",cc
R5481 T9000 T8997 punct ),cc
R5482 T9001 T8986 acomp evident,were
R5483 T9002 T8986 prep at,were
R5484 T9003 T9002 pobj P7,at
R5485 T9004 T8986 prep with,were
R5486 T9005 T9006 amod rudimentary,segments
R5487 T9006 T9004 pobj segments,with
R5488 T9007 T9006 amod outer,segments
R5489 T9008 T8986 punct .,were
R5490 T9010 T9011 prep After,occurs
R5491 T9012 T9010 pobj P7,After
R5492 T9013 T9011 punct ", ",occurs
R5493 T9014 T9011 prep in,occurs
R5494 T9015 T9014 pobj Crx,in
R5495 T9016 T9015 punct +,Crx
R5496 T9017 T9015 punct /,Crx
R5497 T9018 T9015 punct +,Crx
R5498 T9019 T9020 amod outer,segment
R5499 T9020 T9021 compound segment,elongation
R5500 T9021 T9011 nsubj elongation,occurs
R5501 T9022 T9011 punct .,occurs
R5502 T9024 T9025 advmod Initially,have
R5503 T9026 T9025 punct ", ",have
R5504 T9027 T9028 amod outer,segments
R5505 T9028 T9025 nsubj segments,have
R5506 T9029 T9030 det a,structure
R5507 T9030 T9025 dobj structure,have
R5508 T9031 T9032 npadvmod paddle,like
R5509 T9032 T9030 amod like,structure
R5510 T9033 T9032 punct -,like
R5511 T9034 T9035 punct (,os
R5512 T9035 T9030 parataxis os,structure
R5513 T9036 T9035 dep C,os
R5514 T9037 T9035 punct ", ",os
R5515 T9038 T9035 punct ),os
R5516 T9039 T9040 dep which,shed
R5517 T9040 T9030 relcl shed,structure
R5518 T9041 T9040 auxpass is,shed
R5519 T9042 T9040 advmod later,shed
R5520 T9043 T9044 punct (,os
R5521 T9044 T9040 parataxis os,shed
R5522 T9045 T9044 dep E,os
R5523 T9046 T9044 punct ", ",os
R5524 T9047 T9044 punct ),os
R5525 T9048 T9025 punct .,have
R5526 T9050 T9051 prep In,observed
R5527 T9052 T9053 nmod Crx,photoreceptors
R5528 T9053 T9050 pobj photoreceptors,In
R5529 T9054 T9052 punct -,Crx
R5530 T9055 T9052 punct /,Crx
R5531 T9056 T9052 punct -,Crx
R5532 T9057 T9051 punct ", ",observed
R5533 T9058 T9059 amod few,cilia
R5534 T9059 T9051 nsubjpass cilia,observed
R5535 T9060 T9059 amod connecting,cilia
R5536 T9061 T9051 auxpass were,observed
R5537 T9062 T9051 prep at,observed
R5538 T9063 T9062 pobj P7,at
R5539 T9064 T9065 punct (,cc
R5540 T9065 T9051 parataxis cc,observed
R5541 T9066 T9065 dep B,cc
R5542 T9067 T9065 punct ", ",cc
R5543 T9068 T9065 punct ),cc
R5544 T9069 T9051 punct .,observed
R5545 T9071 T9072 prep After,were
R5546 T9073 T9071 pobj P7,After
R5547 T9074 T9072 punct ", ",were
R5548 T9075 T9076 amod connecting,cilia
R5549 T9076 T9072 nsubj cilia,were
R5550 T9077 T9078 advmod more,numerous
R5551 T9078 T9072 acomp numerous,were
R5552 T9079 T9072 cc and,were
R5553 T9080 T9081 advmod occasionally,noted
R5554 T9081 T9072 conj noted,were
R5555 T9082 T9083 det a,segment
R5556 T9083 T9081 nsubjpass segment,noted
R5557 T9084 T9083 amod malformed,segment
R5558 T9085 T9083 amod outer,segment
R5559 T9086 T9081 auxpass was,noted
R5560 T9087 T9081 advcl extending,noted
R5561 T9088 T9087 prep from,extending
R5562 T9089 T9090 det a,cilium
R5563 T9090 T9088 pobj cilium,from
R5564 T9091 T9090 amod connecting,cilium
R5565 T9092 T9093 punct (,cc*
R5566 T9093 T9081 parataxis cc*,noted
R5567 T9094 T9093 dep D,cc*
R5568 T9095 T9094 cc and,D
R5569 T9096 T9094 conj F,D
R5570 T9097 T9093 punct ", ",cc*
R5571 T9098 T9093 punct ),cc*
R5572 T9099 T9081 punct .,noted
R5573 T9101 T9102 nsubjpass These,observed
R5574 T9103 T9102 auxpass were,observed
R5575 T9104 T9102 advmod rarely,observed
R5576 T9105 T9102 prep in,observed
R5577 T9106 T9105 pobj Crx,in
R5578 T9107 T9106 punct +,Crx
R5579 T9108 T9106 punct /,Crx
R5580 T9109 T9106 punct +,Crx
R5581 T9110 T9102 cc and,observed
R5582 T9111 T9112 advmod only,at
R5583 T9112 T9110 prep at,and
R5584 T9113 T9112 pobj P14,at
R5585 T9114 T9115 punct (,cc*
R5586 T9115 T9102 parataxis cc*,observed
R5587 T9116 T9115 dep C,cc*
R5588 T9117 T9115 punct ", ",cc*
R5589 T9118 T9115 punct ),cc*
R5590 T9119 T9102 punct .,observed
R5591 T9121 T9122 prep At,noted
R5592 T9123 T9121 pobj P21,At
R5593 T9124 T9122 punct ", ",noted
R5594 T9125 T9126 advmod abnormally,long
R5595 T9126 T9127 amod long,cilia
R5596 T9127 T9122 nsubjpass cilia,noted
R5597 T9128 T9127 amod connecting,cilia
R5598 T9129 T9122 auxpass are,noted
R5599 T9130 T9122 prep in,noted
R5600 T9131 T9130 pobj Crx,in
R5601 T9132 T9131 punct -,Crx
R5602 T9133 T9131 punct /,Crx
R5603 T9134 T9131 punct -,Crx
R5604 T9135 T9136 punct (,cc
R5605 T9136 T9122 parataxis cc,noted
R5606 T9137 T9136 dep F,cc
R5607 T9138 T9136 punct ", ",cc
R5608 T9139 T9136 punct ),cc
R5609 T9140 T9122 punct .,noted
R5610 T9142 T9143 compound Scale,bars
R5611 T9143 T9144 nsubj bars,μm
R5612 T9145 T9144 punct =,μm
R5613 T9146 T9144 nummod 10,μm
R5616 T9204 T9205 compound Transmission,micrographs
R5617 T9206 T9205 compound electron,micrographs
R5618 T9207 T9205 prep of,micrographs
R5619 T9208 T9209 nmod Crx,photoreceptors
R5620 T9209 T9207 pobj photoreceptors,of
R5621 T9210 T9208 punct -,Crx
R5622 T9211 T9208 punct /,Crx
R5623 T9212 T9208 punct -,Crx
R5624 T9213 T9205 prep in,micrographs
R5625 T9214 T9215 det the,layer
R5626 T9215 T9213 pobj layer,in
R5627 T9216 T9215 compound photoreceptor,layer
R5628 T9217 T9205 prep at,micrographs
R5629 T9218 T9217 pobj P7,at
R5630 T9219 T9205 punct .,micrographs
R5631 T9221 T9222 punct (,A
R5632 T9222 T9223 meta A,layer
R5633 T9224 T9222 punct ),A
R5634 T9225 T9223 compound Photoreceptor,layer
R5635 T9226 T9223 prep of,layer
R5636 T9227 T9228 nmod Crx,retina
R5637 T9228 T9226 pobj retina,of
R5638 T9229 T9227 punct +,Crx
R5639 T9230 T9227 punct /,Crx
R5640 T9231 T9227 punct +,Crx
R5641 T9232 T9223 acl demonstrating,layer
R5642 T9233 T9234 amod nascent,structures
R5643 T9234 T9237 nsubj structures,emerging
R5644 T9235 T9236 amod outer,segment
R5645 T9236 T9234 compound segment,structures
R5646 T9237 T9232 ccomp emerging,demonstrating
R5647 T9238 T9239 punct (,arrow
R5648 T9239 T9237 parataxis arrow,emerging
R5649 T9240 T9239 punct ),arrow
R5650 T9241 T9237 prep from,emerging
R5651 T9242 T9243 nmod photoreceptor,cilia
R5652 T9243 T9241 pobj cilia,from
R5653 T9244 T9243 amod connecting,cilia
R5654 T9245 T9243 punct (,cilia
R5655 T9246 T9243 appos cc,cilia
R5656 T9247 T9243 punct ),cilia
R5657 T9248 T9223 punct .,layer
R5658 T9250 T9251 punct (,B
R5659 T9251 T9252 meta B,observed
R5660 T9253 T9251 punct ),B
R5661 T9254 T9255 nmod Crx,photoreceptors
R5662 T9255 T9259 nsubj photoreceptors,exhibited
R5663 T9256 T9254 punct -,Crx
R5664 T9257 T9254 punct /,Crx
R5665 T9258 T9254 punct -,Crx
R5666 T9259 T9252 ccomp exhibited,observed
R5667 T9260 T9261 amod connecting,cilia
R5668 T9261 T9259 dobj cilia,exhibited
R5669 T9262 T9261 punct (,cilia
R5670 T9263 T9261 appos cc,cilia
R5671 T9264 T9259 punct ),exhibited
R5672 T9265 T9259 prep at,exhibited
R5673 T9266 T9267 det this,stage
R5674 T9267 T9265 pobj stage,at
R5675 T9268 T9267 amod early,stage
R5676 T9269 T9252 punct ", ",observed
R5677 T9270 T9252 advmod however,observed
R5678 T9271 T9252 punct ", ",observed
R5679 T9272 T9273 amod nascent,structures
R5680 T9273 T9252 nsubjpass structures,observed
R5681 T9274 T9275 amod outer,segment
R5682 T9275 T9273 compound segment,structures
R5683 T9276 T9252 auxpass were,observed
R5684 T9277 T9252 neg not,observed
R5685 T9278 T9252 punct .,observed
R5686 T9280 T9281 compound Scale,Bar
R5687 T9281 T9282 nsubj Bar,μm
R5688 T9283 T9282 punct =,μm
R5689 T9284 T9282 nummod 1,μm
R5690 T9285 T9282 punct .,μm
R5691 T9319 T9320 amod Scanning,microscopy
R5692 T9321 T9320 compound electron,microscopy
R5693 T9322 T9320 prep of,microscopy
R5694 T9323 T9324 nmod peripherin,photoreceptors
R5695 T9324 T9322 pobj photoreceptors,of
R5696 T9325 T9323 punct -,peripherin
R5697 T9326 T9323 punct /,peripherin
R5698 T9327 T9323 punct -,peripherin
R5699 T9328 T9329 punct (,A
R5700 T9329 T9323 parataxis A,peripherin
R5701 T9330 T9329 punct ),A
R5702 T9331 T9323 cc and,peripherin
R5703 T9332 T9323 conj rhodopsin,peripherin
R5704 T9333 T9332 punct -,rhodopsin
R5705 T9334 T9332 punct /,rhodopsin
R5706 T9335 T9332 punct -,rhodopsin
R5707 T9336 T9337 punct (,B
R5708 T9337 T9332 parataxis B,rhodopsin
R5709 T9338 T9337 punct ),B
R5710 T9339 T9320 prep at,microscopy
R5711 T9340 T9339 pobj P21,at
R5712 T9341 T9320 punct ", ",microscopy
R5713 T9342 T9320 acl viewed,microscopy
R5714 T9343 T9342 prep from,viewed
R5715 T9344 T9345 det the,side
R5716 T9345 T9343 pobj side,from
R5717 T9346 T9345 amod scleral,side
R5718 T9347 T9348 mark with,removed
R5719 T9348 T9342 advcl removed,viewed
R5720 T9349 T9350 det the,epithelium
R5721 T9350 T9348 nsubj epithelium,removed
R5722 T9351 T9350 amod pigmented,epithelium
R5723 T9352 T9320 punct .,microscopy
R5724 T9355 T9354 punct ", ",cc
R5725 T9356 T9357 amod connecting,cilium
R5726 T9357 T9354 appos cilium,cc
R5727 T9358 T9354 punct .,cc
R5728 T9361 T9360 punct ", ",is
R5729 T9362 T9363 amod inner,segment
R5730 T9363 T9360 appos segment,is
R5731 T9364 T9360 punct .,is
R5732 T9366 T9367 compound Scale,bar
R5733 T9367 T9368 nsubj bar,μm
R5734 T9369 T9368 punct =,μm
R5735 T9370 T9368 nummod 10,μm
R5736 T9371 T9368 punct .,μm
R1348 T2590 T2591 compound ceptor,i
R1349 T2601 T2600 parataxis nd,a
R1350 T2607 T2608 amod r,segments
R1351 T2611 T2610 amod ar,e
R1352 T2615 T2614 agent by,joined
R1353 T2616 T2617 det a,cilium
R1354 T2617 T2615 pobj cilium,by
R1355 T2618 T2617 amod non-motile,cilium
R1356 T2619 T2617 amod connecting,cilium
R1357 T2620 T2621 dep that,exhibits
R1358 T2621 T2617 relcl exhibits,cilium
R1359 T2622 T2623 det a,arrangement
R1360 T2623 T2621 dobj arrangement,exhibits
R1361 T2624 T2623 amod characteristic,arrangement
R1362 T2625 T2626 nummod 9,0
R1363 T2626 T2623 nummod 0,arrangement
R1364 T2627 T2626 punct +,0
R1365 T2628 T2623 prep of,arrangement
R1366 T2629 T2630 compound microtubule,doublets
R1367 T2630 T2628 pobj doublets,of
R1368 T2631 T2632 advmod when,viewed
R1369 T2632 T2621 advcl viewed,exhibits
R1370 T2633 T2632 prep in,viewed
R1371 T2634 T2633 pobj cross-section,in
R1372 T2635 T2614 punct .,joined
R1373 T2637 T2638 prep At,noted
R1374 T2639 T2637 pobj P21,At
R1375 T2640 T2638 punct ", ",noted
R1376 T2641 T2638 prep in,noted
R1377 T2642 T2643 nmod Crx,retinas
R1378 T2643 T2641 pobj retinas,in
R1379 T2644 T2642 punct -,Crx
R1380 T2645 T2642 punct /,Crx
R1381 T2646 T2642 punct -,Crx
R1382 T2647 T2638 punct ", ",noted
R1383 T2648 T2649 amod numerous,sections
R1384 T2649 T2638 nsubjpass sections,noted
R1385 T2650 T2649 compound cross,sections
R1386 T2651 T2649 prep of,sections
R1387 T2652 T2653 amod connecting,cilia
R1388 T2653 T2651 pobj cilia,of
R1468 T2741 T2739 pobj photoreceptors,in
R1471 T2744 T2740 punct -,Crx
R1472 T2745 T2725 punct .,indicate
R1473 T2747 T2748 advmod Further,appeared
R1474 T2749 T2748 punct ", ",appeared
R1475 T2750 T2748 prep in,appeared
R1476 T2751 T2752 nmod Crx,retinas
R1477 T2752 T2750 pobj retinas,in
R1478 T2753 T2751 punct -,Crx
R1479 T2754 T2751 punct /,Crx
R1480 T2755 T2751 punct -,Crx
R1481 T2756 T2757 det the,epithelium
R1482 T2757 T2748 nsubj epithelium,appeared
R1483 T2758 T2757 nmod retinal,epithelium
R1484 T2759 T2757 amod pigmented,epithelium
R1485 T2760 T2757 punct (,epithelium
R1486 T2761 T2757 appos PE,epithelium
R1487 T2762 T2748 punct ),appeared
R1488 T2763 T2748 oprd normal,appeared
R1489 T2764 T2748 punct ", ",appeared
R1490 T2765 T2766 advmod at,least
R1491 T2766 T2767 advmod least,up
R1492 T2767 T2748 prep up,appeared
R1493 T2768 T2767 prep to,up
R1494 T2769 T2768 pobj P21,to
R1495 T2770 T2771 punct (,shown
R1496 T2771 T2769 parataxis shown,P21
R1497 T2772 T2771 nsubj data,shown
R1498 T2773 T2771 neg not,shown
R1499 T2774 T2771 punct ),shown
R1500 T2775 T2769 punct ", ",P21
R1501 T2776 T2777 det the,age
R1502 T2777 T2769 appos age,P21
R1503 T2778 T2777 amod oldest,age
R1504 T2779 T2777 acl examined,age
R1505 T2780 T2748 punct .,appeared
R1506 T2787 T2786 oprd ti,i
R1507 T2788 T2789 amod o,n
R1508 T2792 T2791 pobj t,o
R1509 T2796 T2795 parataxis o,c
R1510 T2801 T2802 compound e,t
R1511 T2804 T2805 compound e,a
R1512 T2807 T2808 amod bs,e
R1513 T2814 T2812 advcl o,o
R1514 T2817 T2818 amod uter,segments
R1515 T2819 T2816 punct ", ",exhibited
R1516 T2820 T2821 nmod Crx,retinas
R1517 T2821 T2816 nsubj retinas,exhibited
R1518 T2822 T2820 punct -,Crx
R1519 T2823 T2820 punct /,Crx
R1520 T2824 T2820 punct -,Crx
R1521 T2825 T2826 nummod three,pathologies
R1522 T2826 T2816 dobj pathologies,exhibited
R1523 T2827 T2826 amod other,pathologies
R1524 T2828 T2826 amod notable,pathologies
R1525 T2829 T2816 prep in,exhibited
R1526 T2830 T2831 det the,layer
R1527 T2831 T2829 pobj layer,in
R1528 T2832 T2833 amod outer,segment
R1529 T2833 T2831 compound segment,layer
R1530 T2834 T2816 punct .,exhibited
R1531 T2836 T2837 advmod First,noted
R1532 T2838 T2837 punct ", ",noted
R1533 T2839 T2840 det an,deposition
R1534 T2840 T2837 nsubjpass deposition,noted
R1535 T2841 T2840 amod abnormal,deposition
R1536 T2842 T2840 prep of,deposition
R1537 T2843 T2842 pobj matrix,of
R1538 T2844 T2843 prep of,matrix
R1539 T2845 T2846 amod unknown,identity
R1540 T2846 T2844 pobj identity,of
R1541 T2847 T2837 auxpass was,noted
R1971 T3310 T3308 pobj formation,of
R1973 T3311 T3312 amod outer,segment
R1976 T3312 T3310 compound segment,formation
R1979 T3313 T3306 prep in,absence
R1983 T3314 T3315 det the,mouse
R1986 T3315 T3313 pobj mouse,in
R1987 T3316 T3315 compound Crx,mouse
R1989 T3317 T3315 compound mutant,mouse
R1993 T3318 T3306 punct ", ",absence
R1997 T3319 T3306 cc and,absence
R2001 T3320 T3321 det the,arrest
R2002 T3321 T3306 conj arrest,absence
R2003 T3322 T3321 prep of,arrest
R2004 T3323 T3322 pobj development,of
R2007 T3324 T3323 prep of,development
R2010 T3325 T3326 det the,appendage
R2014 T3326 T3324 pobj appendage,of
R2018 T3327 T3326 compound photoreceptor,appendage
R2022 T3328 T3321 prep at,arrest
R2028 T3329 T3330 det the,stage
R2033 T3330 T3328 pobj stage,at
R2036 T3331 T3330 compound elongation,stage
R2040 T3332 T3330 prep of,stage
R2042 T3333 T3334 amod outer,segment
R2046 T3334 T3335 compound segment,formation
R2049 T3335 T3332 pobj formation,of
R2053 T3336 T3304 punct .,demonstrate
R1964 T3356 T3355 prep o,ph
R1972 T3367 T3368 det the,photoreceptors
R1974 T3368 T3366 pobj photoreceptors,f
R1975 T3369 T3368 amod malformed,photoreceptors
R1977 T3370 T3368 nmod Crx,photoreceptors
R1978 T3371 T3370 punct -,Crx
R1980 T3372 T3370 punct /,Crx
R1981 T3373 T3370 punct -,Crx
R1982 T3374 T3365 auxpass was,compared
R1984 T3375 T3365 prep to,compared
R1985 T3376 T3377 nmod rhodopsin,photoreceptors