Id |
Subject |
Object |
Predicate |
Lexical cue |
T2359 |
9-17 |
JJ |
denotes |
Multiple |
T2360 |
18-29 |
NNS |
denotes |
pathologies |
T2361 |
30-32 |
IN |
denotes |
in |
T2362 |
33-36 |
DT |
denotes |
the |
T2363 |
51-56 |
NN |
denotes |
layer |
T2364 |
37-42 |
JJ |
denotes |
outer |
T2365 |
43-50 |
NN |
denotes |
segment |
T2366 |
57-59 |
IN |
denotes |
in |
T2367 |
60-63 |
NN |
denotes |
Crx |
T2368 |
67-71 |
NNS |
denotes |
mice |
T2369 |
63-64 |
SYM |
denotes |
- |
T2370 |
64-65 |
HYPH |
denotes |
/ |
T2371 |
65-66 |
SYM |
denotes |
- |
T2372 |
71-188 |
sentence |
denotes |
A standard knock-out protocol was used to generate mice in which the homeodomain of Crx-/- was targeted and deleted. |
T2373 |
72-73 |
DT |
denotes |
A |
T2374 |
93-101 |
NN |
denotes |
protocol |
T2375 |
74-82 |
JJ |
denotes |
standard |
T2376 |
83-88 |
VB |
denotes |
knock |
T2377 |
88-89 |
HYPH |
denotes |
- |
T2378 |
89-92 |
RP |
denotes |
out |
T2379 |
106-110 |
VBN |
denotes |
used |
T2380 |
102-105 |
VBD |
denotes |
was |
T2381 |
111-113 |
TO |
denotes |
to |
T2382 |
114-122 |
VB |
denotes |
generate |
T2383 |
123-127 |
NNS |
denotes |
mice |
T2384 |
128-130 |
IN |
denotes |
in |
T2385 |
167-175 |
VBN |
denotes |
targeted |
T2386 |
131-136 |
WDT |
denotes |
which |
T2387 |
137-140 |
DT |
denotes |
the |
T2388 |
141-152 |
NN |
denotes |
homeodomain |
T2389 |
153-155 |
IN |
denotes |
of |
T2390 |
156-159 |
NN |
denotes |
Crx |
T2391 |
159-160 |
SYM |
denotes |
- |
T2392 |
160-161 |
HYPH |
denotes |
/ |
T2393 |
161-162 |
SYM |
denotes |
- |
T2394 |
163-166 |
VBD |
denotes |
was |
T2395 |
176-179 |
CC |
denotes |
and |
T2396 |
180-187 |
VBN |
denotes |
deleted |
T2397 |
187-188 |
. |
denotes |
. |
T2398 |
188-254 |
sentence |
denotes |
Generation of these Crx-/- mice has been reported elsewhere [34]. |
T2399 |
189-199 |
NN |
denotes |
Generation |
T2400 |
230-238 |
VBN |
denotes |
reported |
T2401 |
200-202 |
IN |
denotes |
of |
T2402 |
203-208 |
DT |
denotes |
these |
T2403 |
216-220 |
NNS |
denotes |
mice |
T2404 |
209-212 |
NN |
denotes |
Crx |
T2405 |
212-213 |
SYM |
denotes |
- |
T2406 |
213-214 |
HYPH |
denotes |
/ |
T2407 |
214-215 |
SYM |
denotes |
- |
T2408 |
221-224 |
VBZ |
denotes |
has |
T2409 |
225-229 |
VBN |
denotes |
been |
T2410 |
239-248 |
RB |
denotes |
elsewhere |
T2411 |
249-250 |
-LRB- |
denotes |
[ |
T2412 |
250-252 |
CD |
denotes |
34 |
T2413 |
252-253 |
-RRB- |
denotes |
] |
T2414 |
253-254 |
. |
denotes |
. |
T2415 |
254-439 |
sentence |
denotes |
In this study, in order to characterize further the role of Crx in photoreceptor morphogenesis, the outer retinae from Crx-/- mice were examined using transmission electron microscopy. |
T2416 |
255-257 |
IN |
denotes |
In |
T2417 |
391-399 |
VBN |
denotes |
examined |
T2418 |
258-262 |
DT |
denotes |
this |
T2419 |
263-268 |
NN |
denotes |
study |
T2420 |
268-270 |
, |
denotes |
, |
T2421 |
270-272 |
IN |
denotes |
in |
T2422 |
273-278 |
NN |
denotes |
order |
T2423 |
279-281 |
TO |
denotes |
to |
T2424 |
282-294 |
VB |
denotes |
characterize |
T2425 |
295-302 |
RB |
denotes |
further |
T2426 |
303-306 |
DT |
denotes |
the |
T2427 |
307-311 |
NN |
denotes |
role |
T2428 |
312-314 |
IN |
denotes |
of |
T2429 |
315-318 |
NN |
denotes |
Crx |
T2430 |
319-321 |
IN |
denotes |
in |
T2431 |
322-335 |
NN |
denotes |
photoreceptor |
T2432 |
336-349 |
NN |
denotes |
morphogenesis |
T2433 |
349-351 |
, |
denotes |
, |
T2434 |
351-354 |
DT |
denotes |
the |
T2435 |
361-368 |
NNS |
denotes |
retinae |
T2436 |
355-360 |
JJ |
denotes |
outer |
T2437 |
369-373 |
IN |
denotes |
from |
T2438 |
374-377 |
NN |
denotes |
Crx |
T2439 |
381-385 |
NNS |
denotes |
mice |
T2440 |
377-378 |
SYM |
denotes |
- |
T2441 |
378-379 |
HYPH |
denotes |
/ |
T2442 |
379-380 |
SYM |
denotes |
- |
T2443 |
386-390 |
VBD |
denotes |
were |
T2444 |
400-405 |
VBG |
denotes |
using |
T2445 |
406-418 |
NN |
denotes |
transmission |
T2446 |
428-438 |
NN |
denotes |
microscopy |
T2447 |
419-427 |
NN |
denotes |
electron |
T2448 |
438-439 |
. |
denotes |
. |
T2449 |
439-618 |
sentence |
denotes |
At postnatal day 21 (P21), when Crx+/+ photoreceptors exhibited robust outer segments (Figure 1A, os), Crx-/- retinas were without a recognizable outer segment layer (Figure 1B). |
T2450 |
440-442 |
IN |
denotes |
At |
T2451 |
558-562 |
VBD |
denotes |
were |
T2452 |
443-452 |
JJ |
denotes |
postnatal |
T2453 |
453-456 |
NN |
denotes |
day |
T2454 |
457-459 |
CD |
denotes |
21 |
T2455 |
460-461 |
-LRB- |
denotes |
( |
T2456 |
461-464 |
NN |
denotes |
P21 |
T2457 |
464-465 |
-RRB- |
denotes |
) |
T2458 |
465-467 |
, |
denotes |
, |
T2459 |
467-471 |
WRB |
denotes |
when |
T2460 |
494-503 |
VBD |
denotes |
exhibited |
T2461 |
472-475 |
NN |
denotes |
Crx |
T2462 |
479-493 |
NNS |
denotes |
photoreceptors |
T2463 |
475-476 |
SYM |
denotes |
+ |
T2464 |
476-477 |
HYPH |
denotes |
/ |
T2465 |
477-478 |
SYM |
denotes |
+ |
T2466 |
504-510 |
JJ |
denotes |
robust |
T2467 |
517-525 |
NNS |
denotes |
segments |
T2468 |
511-516 |
JJ |
denotes |
outer |
T2469 |
526-527 |
-LRB- |
denotes |
( |
T2470 |
538-540 |
NN |
denotes |
os |
T2471 |
527-533 |
NN |
denotes |
Figure |
T2472 |
534-536 |
NN |
denotes |
1A |
T2473 |
536-538 |
, |
denotes |
, |
T2474 |
540-541 |
-RRB- |
denotes |
) |
T2475 |
541-543 |
, |
denotes |
, |
T2476 |
543-546 |
NN |
denotes |
Crx |
T2477 |
550-557 |
NNS |
denotes |
retinas |
T2478 |
546-547 |
SYM |
denotes |
- |
T2479 |
547-548 |
HYPH |
denotes |
/ |
T2480 |
548-549 |
SYM |
denotes |
- |
T2481 |
563-570 |
IN |
denotes |
without |
T2482 |
571-572 |
DT |
denotes |
a |
T2483 |
600-605 |
NN |
denotes |
layer |
T2484 |
573-585 |
JJ |
denotes |
recognizable |
T2485 |
586-591 |
JJ |
denotes |
outer |
T2486 |
592-599 |
NN |
denotes |
segment |
T2487 |
606-607 |
-LRB- |
denotes |
( |
T2488 |
607-613 |
NN |
denotes |
Figure |
T2489 |
614-616 |
CD |
denotes |
1B |
T2490 |
616-617 |
-RRB- |
denotes |
) |
T2491 |
617-618 |
. |
denotes |
. |
T2492 |
618-793 |
sentence |
denotes |
Crx-/- photoreceptors had inner segments, demonstrating at least limited photoreceptor polarization in the Crx mutant, but the inner segments were extremely short (Figure 2). |
T2493 |
619-622 |
NN |
denotes |
Crx |
T2494 |
626-640 |
NNS |
denotes |
photoreceptors |
T2495 |
622-623 |
SYM |
denotes |
- |
T2496 |
623-624 |
HYPH |
denotes |
/ |
T2497 |
624-625 |
SYM |
denotes |
- |
T2498 |
641-644 |
VBD |
denotes |
had |
T2499 |
645-650 |
JJ |
denotes |
inner |
T2500 |
651-659 |
NNS |
denotes |
segments |
T2501 |
659-661 |
, |
denotes |
, |
T2502 |
661-674 |
VBG |
denotes |
demonstrating |
T2503 |
675-677 |
RB |
denotes |
at |
T2504 |
678-683 |
RBS |
denotes |
least |
T2505 |
684-691 |
JJ |
denotes |
limited |
T2506 |
706-718 |
NN |
denotes |
polarization |
T2507 |
692-705 |
NN |
denotes |
photoreceptor |
T2508 |
719-721 |
IN |
denotes |
in |
T2509 |
722-725 |
DT |
denotes |
the |
T2510 |
730-736 |
NN |
denotes |
mutant |
T2511 |
726-729 |
NN |
denotes |
Crx |
T2512 |
736-738 |
, |
denotes |
, |
T2513 |
738-741 |
CC |
denotes |
but |
T2514 |
742-745 |
DT |
denotes |
the |
T2515 |
752-760 |
NNS |
denotes |
segments |
T2516 |
746-751 |
JJ |
denotes |
inner |
T2517 |
761-765 |
VBD |
denotes |
were |
T2518 |
766-775 |
RB |
denotes |
extremely |
T2519 |
776-781 |
JJ |
denotes |
short |
T2520 |
782-783 |
-LRB- |
denotes |
( |
T2521 |
783-789 |
NN |
denotes |
Figure |
T2522 |
790-791 |
CD |
denotes |
2 |
T2523 |
791-792 |
-RRB- |
denotes |
) |
T2524 |
792-793 |
. |
denotes |
. |
T2525 |
793-955 |
sentence |
denotes |
Furthermore, the majority of inner segments showed some morphological differentiation, having approximately as many mitochondria as the control (Figure 1 and 2). |
T2526 |
794-805 |
RB |
denotes |
Furthermore |
T2527 |
838-844 |
VBD |
denotes |
showed |
T2528 |
805-807 |
, |
denotes |
, |
T2529 |
807-810 |
DT |
denotes |
the |
T2530 |
811-819 |
NN |
denotes |
majority |
T2531 |
820-822 |
IN |
denotes |
of |
T2532 |
823-828 |
JJ |
denotes |
inner |
T2533 |
829-837 |
NNS |
denotes |
segments |
T2534 |
845-849 |
DT |
denotes |
some |
T2535 |
864-879 |
NN |
denotes |
differentiation |
T2536 |
850-863 |
JJ |
denotes |
morphological |
T2537 |
879-881 |
, |
denotes |
, |
T2538 |
881-887 |
VBG |
denotes |
having |
T2539 |
888-901 |
RB |
denotes |
approximately |
T2540 |
905-909 |
JJ |
denotes |
many |
T2541 |
902-904 |
RB |
denotes |
as |
T2542 |
910-922 |
NNS |
denotes |
mitochondria |
T2543 |
923-925 |
IN |
denotes |
as |
T2544 |
926-929 |
DT |
denotes |
the |
T2545 |
930-937 |
NN |
denotes |
control |
T2546 |
938-939 |
-LRB- |
denotes |
( |
T2547 |
946-947 |
CD |
denotes |
1 |
T2641 |
1857-1859 |
IN |
denotes |
in |
T2642 |
1860-1863 |
NN |
denotes |
Crx |
T2643 |
1867-1874 |
NNS |
denotes |
retinas |
T2644 |
1863-1864 |
SYM |
denotes |
- |
T2645 |
1864-1865 |
HYPH |
denotes |
/ |
T2646 |
1865-1866 |
SYM |
denotes |
- |
T2647 |
1874-1876 |
, |
denotes |
, |
T2648 |
1876-1884 |
JJ |
denotes |
numerous |
T2649 |
1891-1899 |
NNS |
denotes |
sections |
T2650 |
1885-1890 |
NN |
denotes |
cross |
T2651 |
1900-1902 |
IN |
denotes |
of |
T2652 |
1903-1913 |
JJ |
denotes |
connecting |
T2653 |
1914-1919 |
NNS |
denotes |
cilia |
T2654 |
1920-1924 |
VBD |
denotes |
were |
T2655 |
1931-1932 |
-LRB- |
denotes |
( |
T2656 |
1939-1941 |
CD |
denotes |
3A |
T2657 |
1932-1938 |
NN |
denotes |
Figure |
T2658 |
1942-1945 |
CC |
denotes |
and |
T2659 |
1946-1948 |
CD |
denotes |
3B |
T2660 |
1948-1949 |
-RRB- |
denotes |
) |
T2661 |
1949-1950 |
. |
denotes |
. |
T2662 |
1950-2050 |
sentence |
denotes |
Sporadically, connecting cilia contained other than the typical complement of microtubule doublets. |
T2663 |
1951-1963 |
RB |
denotes |
Sporadically |
T2664 |
1982-1991 |
VBD |
denotes |
contained |
T2665 |
1963-1965 |
, |
denotes |
, |
T2666 |
1965-1975 |
JJ |
denotes |
connecting |
T2667 |
1976-1981 |
NNS |
denotes |
cilia |
T2668 |
1992-1997 |
JJ |
denotes |
other |
T2669 |
1998-2002 |
IN |
denotes |
than |
T2670 |
2003-2006 |
DT |
denotes |
the |
T2671 |
2015-2025 |
NN |
denotes |
complement |
T2672 |
2007-2014 |
JJ |
denotes |
typical |
T2673 |
2026-2028 |
IN |
denotes |
of |
T2674 |
2029-2040 |
NN |
denotes |
microtubule |
T2675 |
2041-2049 |
NNS |
denotes |
doublets |
T2676 |
2049-2050 |
. |
denotes |
. |
T2677 |
2050-2146 |
sentence |
denotes |
For example, in Figure 3A, the connecting cilium labelled by arrowhead 1, shows 7 + 0 doublets. |
T2678 |
2051-2054 |
IN |
denotes |
For |
T2679 |
2125-2130 |
VBZ |
denotes |
shows |
T2680 |
2055-2062 |
NN |
denotes |
example |
T2681 |
2062-2064 |
, |
denotes |
, |
T2682 |
2064-2066 |
IN |
denotes |
in |
T2683 |
2067-2073 |
NN |
denotes |
Figure |
T2684 |
2074-2076 |
NN |
denotes |
3A |
T2685 |
2076-2078 |
, |
denotes |
, |
T2686 |
2078-2081 |
DT |
denotes |
the |
T2687 |
2093-2099 |
NN |
denotes |
cilium |
T2688 |
2082-2092 |
JJ |
denotes |
connecting |
T2689 |
2100-2108 |
VBN |
denotes |
labelled |
T2690 |
2109-2111 |
IN |
denotes |
by |
T2691 |
2112-2121 |
NN |
denotes |
arrowhead |
T2692 |
2122-2123 |
CD |
denotes |
1 |
T2693 |
2123-2125 |
, |
denotes |
, |
T2694 |
2131-2132 |
CD |
denotes |
7 |
T2695 |
2135-2136 |
CD |
denotes |
0 |
T2696 |
2133-2134 |
SYM |
denotes |
+ |
T2697 |
2137-2145 |
NNS |
denotes |
doublets |
T2698 |
2145-2146 |
. |
denotes |
. |
T2699 |
2146-2251 |
sentence |
denotes |
The majority exhibited the characteristic 9 + 0 doublets (arrowhead 2 and 3 in Figure 3A and Figure 3B). |
T2700 |
2147-2150 |
DT |
denotes |
The |
T2701 |
2151-2159 |
NN |
denotes |
majority |
T2702 |
2160-2169 |
VBD |
denotes |
exhibited |
T2703 |
2170-2173 |
DT |
denotes |
the |
T2704 |
2195-2203 |
NNS |
denotes |
doublets |
T2705 |
2174-2188 |
JJ |
denotes |
characteristic |
T2706 |
2189-2190 |
CD |
denotes |
9 |
T2707 |
2193-2194 |
CD |
denotes |
0 |
T2708 |
2191-2192 |
SYM |
denotes |
+ |
T2709 |
2204-2205 |
-LRB- |
denotes |
( |
T2710 |
2215-2216 |
CD |
denotes |
2 |
T2711 |
2205-2214 |
NN |
denotes |
arrowhead |
T2712 |
2217-2220 |
CC |
denotes |
and |
T2713 |
2221-2222 |
CD |
denotes |
3 |
T2714 |
2223-2225 |
IN |
denotes |
in |
T2715 |
2226-2232 |
NN |
denotes |
Figure |
T2716 |
2233-2235 |
NN |
denotes |
3A |
T2717 |
2236-2239 |
CC |
denotes |
and |
T2718 |
2240-2246 |
NN |
denotes |
Figure |
T2719 |
2247-2249 |
NN |
denotes |
3B |
T2720 |
2249-2250 |
-RRB- |
denotes |
) |
T2721 |
2250-2251 |
. |
denotes |
. |
T2722 |
2251-2386 |
sentence |
denotes |
These observations indicate that in addition to inner segment formation, ciliogenesis is also largely intact in Crx-/- photoreceptors. |
T2723 |
2252-2257 |
DT |
denotes |
These |
T2724 |
2258-2270 |
NNS |
denotes |
observations |
T2725 |
2271-2279 |
VBP |
denotes |
indicate |
T2726 |
2280-2284 |
IN |
denotes |
that |
T2727 |
2338-2340 |
VBZ |
denotes |
is |
T2728 |
2285-2287 |
IN |
denotes |
in |
T2729 |
2288-2296 |
NN |
denotes |
addition |
T2730 |
2297-2299 |
IN |
denotes |
to |
T2731 |
2300-2305 |
JJ |
denotes |
inner |
T2732 |
2306-2313 |
NN |
denotes |
segment |
T2733 |
2314-2323 |
NN |
denotes |
formation |
T2734 |
2323-2325 |
, |
denotes |
, |
T2735 |
2325-2337 |
NN |
denotes |
ciliogenesis |
T2736 |
2341-2345 |
RB |
denotes |
also |
T2737 |
2346-2353 |
RB |
denotes |
largely |
T2738 |
2354-2360 |
JJ |
denotes |
intact |
T2739 |
2361-2363 |
IN |
denotes |
in |
T2740 |
2364-2367 |
NN |
denotes |
Crx |
T2741 |
2371-2385 |
NNS |
denotes |
photoreceptors |
T2742 |
2367-2368 |
SYM |
denotes |
- |
T2743 |
2368-2369 |
HYPH |
denotes |
/ |
T2744 |
2369-2370 |
SYM |
denotes |
- |
T2745 |
2385-2386 |
. |
denotes |
. |
T2746 |
2386-2530 |
sentence |
denotes |
Further, in Crx-/- retinas the retinal pigmented epithelium (PE) appeared normal, at least up to P21 (data not shown), the oldest age examined. |
T2836 |
3840-3845 |
RB |
denotes |
First |
T2837 |
3904-3909 |
VBN |
denotes |
noted |
T2838 |
3845-3847 |
, |
denotes |
, |
T2839 |
3847-3849 |
DT |
denotes |
an |
T2840 |
3859-3869 |
NN |
denotes |
deposition |
T2841 |
3850-3858 |
JJ |
denotes |
abnormal |
T2842 |
3870-3872 |
IN |
denotes |
of |
T2843 |
3873-3879 |
NN |
denotes |
matrix |
T2844 |
3880-3882 |
IN |
denotes |
of |
T2845 |
3883-3890 |
JJ |
denotes |
unknown |
T2846 |
3891-3899 |
NN |
denotes |
identity |
T2847 |
3900-3903 |
VBD |
denotes |
was |
T2848 |
3910-3911 |
-LRB- |
denotes |
( |
T2849 |
3922-3924 |
NN |
denotes |
mx |
T2850 |
3911-3917 |
NN |
denotes |
Figure |
T2851 |
3918-3920 |
NN |
denotes |
3A |
T2852 |
3920-3922 |
, |
denotes |
, |
T2853 |
3924-3925 |
-RRB- |
denotes |
) |
T2854 |
3925-3926 |
. |
denotes |
. |
T2855 |
3926-4014 |
sentence |
denotes |
Second, sporadically displaced nuclei were found residing in the space abutting the PE. |
T2856 |
3927-3933 |
RB |
denotes |
Second |
T2857 |
3970-3975 |
VBN |
denotes |
found |
T2858 |
3933-3935 |
, |
denotes |
, |
T2859 |
3935-3947 |
RB |
denotes |
sporadically |
T2860 |
3948-3957 |
VBN |
denotes |
displaced |
T2861 |
3958-3964 |
NNS |
denotes |
nuclei |
T2862 |
3965-3969 |
VBD |
denotes |
were |
T2863 |
3976-3984 |
VBG |
denotes |
residing |
T2864 |
3985-3987 |
IN |
denotes |
in |
T2865 |
3988-3991 |
DT |
denotes |
the |
T2866 |
3992-3997 |
NN |
denotes |
space |
T2867 |
3998-4006 |
VBG |
denotes |
abutting |
T2868 |
4007-4010 |
DT |
denotes |
the |
T2869 |
4011-4013 |
NN |
denotes |
PE |
T2870 |
4013-4014 |
. |
denotes |
. |
T2871 |
4014-4244 |
sentence |
denotes |
Occasionally, these nuclei appeared pyknotic (Figure 3A, n); but, more frequently exhibited the heterochromatin pattern typical of photoreceptors (data not shown), strongly suggesting that they belonged to ectopic photoreceptors. |
T2872 |
4015-4027 |
RB |
denotes |
Occasionally |
T2873 |
4042-4050 |
VBD |
denotes |
appeared |
T2874 |
4027-4029 |
, |
denotes |
, |
T2875 |
4029-4034 |
DT |
denotes |
these |
T2876 |
4035-4041 |
NNS |
denotes |
nuclei |
T2877 |
4051-4059 |
JJ |
denotes |
pyknotic |
T2878 |
4060-4061 |
-LRB- |
denotes |
( |
T2879 |
4072-4073 |
NN |
denotes |
n |
T2880 |
4061-4067 |
NN |
denotes |
Figure |
T2881 |
4068-4070 |
NN |
denotes |
3A |
T2882 |
4070-4072 |
, |
denotes |
, |
T2883 |
4073-4074 |
-RRB- |
denotes |
) |
T2884 |
4074-4075 |
: |
denotes |
; |
T2885 |
4076-4079 |
CC |
denotes |
but |
T2886 |
4079-4081 |
, |
denotes |
, |
T2887 |
4081-4085 |
RBR |
denotes |
more |
T2888 |
4086-4096 |
RB |
denotes |
frequently |
T2889 |
4097-4106 |
VBD |
denotes |
exhibited |
T2890 |
4107-4110 |
DT |
denotes |
the |
T2891 |
4127-4134 |
NN |
denotes |
pattern |
T2892 |
4111-4126 |
NN |
denotes |
heterochromatin |
T2893 |
4135-4142 |
JJ |
denotes |
typical |
T2894 |
4143-4145 |
IN |
denotes |
of |
T2895 |
4146-4160 |
NNS |
denotes |
photoreceptors |
T2896 |
4161-4162 |
-LRB- |
denotes |
( |
T2897 |
4171-4176 |
VBN |
denotes |
shown |
T2898 |
4162-4166 |
NNS |
denotes |
data |
T2899 |
4167-4170 |
RB |
denotes |
not |
T2900 |
4176-4177 |
-RRB- |
denotes |
) |
T2901 |
4177-4179 |
, |
denotes |
, |
T2902 |
4179-4187 |
RB |
denotes |
strongly |
T2903 |
4188-4198 |
VBG |
denotes |
suggesting |
T2904 |
4199-4203 |
IN |
denotes |
that |
T2905 |
4209-4217 |
VBD |
denotes |
belonged |
T2906 |
4204-4208 |
PRP |
denotes |
they |
T2907 |
4218-4220 |
IN |
denotes |
to |
T2908 |
4221-4228 |
JJ |
denotes |
ectopic |
T2909 |
4229-4243 |
NNS |
denotes |
photoreceptors |
T2910 |
4243-4244 |
. |
denotes |
. |
T2911 |
4244-4381 |
sentence |
denotes |
The third pathological entity noted in the outer segment layer were numerous small vesicles (Figure 3A arrow) 100 to 200 nm in diameter. |
T2912 |
4245-4248 |
DT |
denotes |
The |
T2913 |
4268-4274 |
NN |
denotes |
entity |
T2914 |
4249-4254 |
JJ |
denotes |
third |
T2915 |
4255-4267 |
JJ |
denotes |
pathological |
T2916 |
4308-4312 |
VBD |
denotes |
were |
T2917 |
4275-4280 |
VBN |
denotes |
noted |
T2918 |
4281-4283 |
IN |
denotes |
in |
T2919 |
4284-4287 |
DT |
denotes |
the |
T2920 |
4302-4307 |
NN |
denotes |
layer |
T2921 |
4288-4293 |
JJ |
denotes |
outer |
T2922 |
4294-4301 |
NN |
denotes |
segment |
T2923 |
4313-4321 |
JJ |
denotes |
numerous |
T2924 |
4328-4336 |
NNS |
denotes |
vesicles |
T2925 |
4322-4327 |
JJ |
denotes |
small |
T2926 |
4337-4338 |
-LRB- |
denotes |
( |
T2927 |
4348-4353 |
NN |
denotes |
arrow |
T2928 |
4338-4344 |
NN |
denotes |
Figure |
T2929 |
4345-4347 |
NN |
denotes |
3A |
T2930 |
4353-4354 |
-RRB- |
denotes |
) |
T2931 |
4355-4358 |
CD |
denotes |
100 |
T2932 |
4362-4365 |
CD |
denotes |
200 |
T2933 |
4359-4361 |
IN |
denotes |
to |
T2934 |
4366-4368 |
NN |
denotes |
nm |
T2935 |
4369-4371 |
IN |
denotes |
in |
T2936 |
4372-4380 |
NN |
denotes |
diameter |
T2937 |
4380-4381 |
. |
denotes |
. |
T2938 |
4381-4555 |
sentence |
denotes |
They appeared to be emerging from the inner segments, as scanning electron microscopic images showed spherical structures budding from the inner segments (Figure 3C, arrow). |
T2939 |
4382-4386 |
PRP |
denotes |
They |
T2940 |
4387-4395 |
VBD |
denotes |
appeared |
T2941 |
4396-4398 |
TO |
denotes |
to |
T2942 |
4402-4410 |
VBG |
denotes |
emerging |
T2943 |
4399-4401 |
VB |
denotes |
be |
T2944 |
4411-4415 |
IN |
denotes |
from |
T2945 |
4416-4419 |
DT |
denotes |
the |
T2946 |
4426-4434 |
NNS |
denotes |
segments |
T2947 |
4420-4425 |
JJ |
denotes |
inner |
T2948 |
4434-4436 |
, |
denotes |
, |
T2949 |
4436-4438 |
IN |
denotes |
as |
T2950 |
4476-4482 |
VBD |
denotes |
showed |
T2951 |
4439-4447 |
VBG |
denotes |
scanning |
T2952 |
4448-4456 |
NN |
denotes |
electron |
T2953 |
4457-4468 |
JJ |
denotes |
microscopic |
T2954 |
4469-4475 |
NNS |
denotes |
images |
T2955 |
4483-4492 |
JJ |
denotes |
spherical |
T2956 |
4493-4503 |
NNS |
denotes |
structures |
T2957 |
4504-4511 |
VBG |
denotes |
budding |
T2958 |
4512-4516 |
IN |
denotes |
from |
T2959 |
4517-4520 |
DT |
denotes |
the |
T2960 |
4527-4535 |
NNS |
denotes |
segments |
T2961 |
4521-4526 |
JJ |
denotes |
inner |
T2962 |
4536-4537 |
-LRB- |
denotes |
( |
T2963 |
4548-4553 |
NN |
denotes |
arrow |
T2964 |
4537-4543 |
NN |
denotes |
Figure |
T2965 |
4544-4546 |
NN |
denotes |
3C |
T2966 |
4546-4548 |
, |
denotes |
, |
T2967 |
4553-4554 |
-RRB- |
denotes |
) |
T2968 |
4554-4555 |
. |
denotes |
. |
T2969 |
4555-4741 |
sentence |
denotes |
In order to characterize further the morphogenesis of Crx-/- photoreceptors, the developing outer segment layer was viewed by scanning electron microscopy at P7, P14 and P21 (Figure 4). |
T2970 |
4556-4558 |
IN |
denotes |
In |
T2971 |
4672-4678 |
VBN |
denotes |
viewed |
T2972 |
4559-4564 |
NN |
denotes |
order |
T2973 |
4565-4567 |
TO |
denotes |
to |
T2974 |
4568-4580 |
VB |
denotes |
characterize |
T2975 |
4581-4588 |
RB |
denotes |
further |
T2976 |
4589-4592 |
DT |
denotes |
the |
T2977 |
4593-4606 |
NN |
denotes |
morphogenesis |
T2978 |
4607-4609 |
IN |
denotes |
of |
T2979 |
4610-4613 |
NN |
denotes |
Crx |
T2980 |
4617-4631 |
NNS |
denotes |
photoreceptors |
T2981 |
4613-4614 |
SYM |
denotes |
- |
T2982 |
4614-4615 |
HYPH |
denotes |
/ |
T2983 |
4615-4616 |
SYM |
denotes |
- |
T2984 |
4631-4633 |
, |
denotes |
, |
T2985 |
4633-4636 |
DT |
denotes |
the |
T2986 |
4662-4667 |
NN |
denotes |
layer |
T2987 |
4637-4647 |
VBG |
denotes |
developing |
T2988 |
4648-4653 |
JJ |
denotes |
outer |
T2989 |
4654-4661 |
NN |
denotes |
segment |
T2990 |
4668-4671 |
VBD |
denotes |
was |
T2991 |
4679-4681 |
IN |
denotes |
by |
T2992 |
4682-4690 |
VBG |
denotes |
scanning |
T2993 |
4700-4710 |
NN |
denotes |
microscopy |
T2994 |
4691-4699 |
NN |
denotes |
electron |
T2995 |
4711-4713 |
IN |
denotes |
at |
T2996 |
4714-4716 |
NN |
denotes |
P7 |
T2997 |
4716-4718 |
, |
denotes |
, |
T2998 |
4718-4721 |
NN |
denotes |
P14 |
T2999 |
4722-4725 |
CC |
denotes |
and |
T3000 |
4726-4729 |
NN |
denotes |
P21 |
T3001 |
4730-4731 |
-LRB- |
denotes |
( |
T3002 |
4731-4737 |
NN |
denotes |
Figure |
T3003 |
4738-4739 |
CD |
denotes |
4 |
T3004 |
4739-4740 |
-RRB- |
denotes |
) |
T3005 |
4740-4741 |
. |
denotes |
. |
T3006 |
4741-4877 |
sentence |
denotes |
In Crx+/+ retinas, photoreceptor inner segments, connecting cilia, and the first rudimentary outer segment structures were noted at P7. |
T3007 |
4742-4744 |
IN |
denotes |
In |
T3008 |
4865-4870 |
VBN |
denotes |
noted |
T3009 |
4745-4748 |
NN |
denotes |
Crx |
T3010 |
4752-4759 |
NNS |
denotes |
retinas |
T3011 |
4748-4749 |
SYM |
denotes |
+ |
T3012 |
4749-4750 |
HYPH |
denotes |
/ |
T3013 |
4750-4751 |
SYM |
denotes |
+ |
T3014 |
4759-4761 |
, |
denotes |
, |
T3015 |
4761-4774 |
NN |
denotes |
photoreceptor |
T3016 |
4781-4789 |
NNS |
denotes |
segments |
T3017 |
4775-4780 |
JJ |
denotes |
inner |
T3018 |
4789-4791 |
, |
denotes |
, |
T3019 |
4791-4801 |
VBG |
denotes |
connecting |
T3020 |
4802-4807 |
NNS |
denotes |
cilia |
T3021 |
4807-4809 |
, |
denotes |
, |
T3022 |
4809-4812 |
CC |
denotes |
and |
T3023 |
4813-4816 |
DT |
denotes |
the |
T3024 |
4849-4859 |
NNS |
denotes |
structures |
T3025 |
4817-4822 |
JJ |
denotes |
first |
T3026 |
4823-4834 |
JJ |
denotes |
rudimentary |
T3027 |
4835-4840 |
JJ |
denotes |
outer |
T3028 |
4841-4848 |
NN |
denotes |
segment |
T3029 |
4860-4864 |
VBD |
denotes |
were |
T3030 |
4871-4873 |
IN |
denotes |
at |
T3031 |
4874-4876 |
NN |
denotes |
P7 |
T3032 |
4876-4877 |
. |
denotes |
. |
T3033 |
4877-5010 |
sentence |
denotes |
In the Crx-/- retina, only an occassional connecting cilium was noted emerging from inner segments at this stage (Figure 4A and 4B). |
T3034 |
4878-4880 |
IN |
denotes |
In |
T3035 |
4948-4956 |
VBG |
denotes |
emerging |
T3036 |
4881-4884 |
DT |
denotes |
the |
T3037 |
4892-4898 |
NN |
denotes |
retina |
T3038 |
4885-4888 |
NN |
denotes |
Crx |
T3039 |
4888-4889 |
SYM |
denotes |
- |
T3040 |
4889-4890 |
HYPH |
denotes |
/ |
T3041 |
4890-4891 |
SYM |
denotes |
- |
T3042 |
4898-4900 |
, |
denotes |
, |
T3043 |
4900-4904 |
RB |
denotes |
only |
T3044 |
4931-4937 |
NN |
denotes |
cilium |
T3045 |
4905-4907 |
DT |
denotes |
an |
T3046 |
4908-4919 |
JJ |
denotes |
occassional |
T3047 |
4920-4930 |
VBG |
denotes |
connecting |
T3048 |
4938-4941 |
VBD |
denotes |
was |
T3049 |
4942-4947 |
VBN |
denotes |
noted |
T3050 |
4957-4961 |
IN |
denotes |
from |
T3051 |
4962-4967 |
JJ |
denotes |
inner |
T3052 |
4968-4976 |
NNS |
denotes |
segments |
T3053 |
4977-4979 |
IN |
denotes |
at |
T3054 |
4980-4984 |
DT |
denotes |
this |
T3055 |
4985-4990 |
NN |
denotes |
stage |
T3056 |
4991-4992 |
-LRB- |
denotes |
( |
T3057 |
4999-5001 |
NN |
denotes |
4A |
T3058 |
4992-4998 |
NN |
denotes |
Figure |
T3059 |
5002-5005 |
CC |
denotes |
and |
T3060 |
5006-5008 |
NN |
denotes |
4B |
T3061 |
5008-5009 |
-RRB- |
denotes |
) |
T3062 |
5009-5010 |
. |
denotes |
. |
T3063 |
5010-5106 |
sentence |
denotes |
This observation was confirmed by comparison with transmission electron micrographs (Figure 5). |
T3064 |
5011-5015 |
DT |
denotes |
This |
T3065 |
5016-5027 |
NN |
denotes |
observation |
T3066 |
5032-5041 |
VBN |
denotes |
confirmed |
T3067 |
5028-5031 |
VBD |
denotes |
was |
T3068 |
5042-5044 |
IN |
denotes |
by |
T3069 |
5045-5055 |
NN |
denotes |
comparison |
T3070 |
5056-5060 |
IN |
denotes |
with |
T3071 |
5061-5073 |
NN |
denotes |
transmission |
T3072 |
5083-5094 |
NNS |
denotes |
micrographs |
T3073 |
5074-5082 |
NN |
denotes |
electron |
T3074 |
5095-5096 |
-LRB- |
denotes |
( |
T3075 |
5096-5102 |
NN |
denotes |
Figure |
T3076 |
5103-5104 |
CD |
denotes |
5 |
T3077 |
5104-5105 |
-RRB- |
denotes |
) |
T3078 |
5105-5106 |
. |
denotes |
. |
T3079 |
5106-5201 |
sentence |
denotes |
These differences are the earliest noted differences between Crx+/+ and Crx-/- photoreceptors. |
T3080 |
5107-5112 |
DT |
denotes |
These |
T3081 |
5113-5124 |
NNS |
denotes |
differences |
T3082 |
5125-5128 |
VBP |
denotes |
are |
T3083 |
5129-5132 |
DT |
denotes |
the |
T3084 |
5148-5159 |
NNS |
denotes |
differences |
T3085 |
5133-5141 |
JJS |
denotes |
earliest |
T3086 |
5142-5147 |
VBN |
denotes |
noted |
T3087 |
5160-5167 |
IN |
denotes |
between |
T3088 |
5168-5171 |
NN |
denotes |
Crx |
T3089 |
5186-5200 |
NNS |
denotes |
photoreceptors |
T3090 |
5171-5172 |
SYM |
denotes |
+ |
T3091 |
5172-5173 |
HYPH |
denotes |
/ |
T3092 |
5173-5174 |
SYM |
denotes |
+ |
T3093 |
5175-5178 |
CC |
denotes |
and |
T3094 |
5179-5182 |
NN |
denotes |
Crx |
T3095 |
5182-5183 |
SYM |
denotes |
- |
T3096 |
5183-5184 |
HYPH |
denotes |
/ |
T3097 |
5184-5185 |
SYM |
denotes |
- |
T3098 |
5200-5201 |
. |
denotes |
. |
T3099 |
5201-5354 |
sentence |
denotes |
At P14, elongating outer segments were noted on Crx+/+ photoreceptors, occasionally demonstrating a paddle-like structure at their apex (Figure 4C, os). |
T3100 |
5202-5204 |
IN |
denotes |
At |
T3101 |
5241-5246 |
VBN |
denotes |
noted |
T3102 |
5205-5208 |
NN |
denotes |
P14 |
T3103 |
5208-5210 |
, |
denotes |
, |
T3104 |
5210-5220 |
VBG |
denotes |
elongating |
T3105 |
5227-5235 |
NNS |
denotes |
segments |
T3106 |
5221-5226 |
JJ |
denotes |
outer |
T3107 |
5236-5240 |
VBD |
denotes |
were |
T3108 |
5247-5249 |
IN |
denotes |
on |
T3109 |
5250-5253 |
NN |
denotes |
Crx |
T3110 |
5257-5271 |
NNS |
denotes |
photoreceptors |
T3111 |
5253-5254 |
SYM |
denotes |
+ |
T3112 |
5254-5255 |
HYPH |
denotes |
/ |
T3113 |
5255-5256 |
SYM |
denotes |
+ |
T3114 |
5271-5273 |
, |
denotes |
, |
T3115 |
5273-5285 |
RB |
denotes |
occasionally |
T3116 |
5286-5299 |
VBG |
denotes |
demonstrating |
T3117 |
5300-5301 |
DT |
denotes |
a |
T3118 |
5314-5323 |
NN |
denotes |
structure |
T3119 |
5302-5308 |
NN |
denotes |
paddle |
T3120 |
5309-5313 |
JJ |
denotes |
like |
T3121 |
5308-5309 |
HYPH |
denotes |
- |
T3122 |
5324-5326 |
IN |
denotes |
at |
T3123 |
5327-5332 |
PRP$ |
denotes |
their |
T3124 |
5333-5337 |
NN |
denotes |
apex |
T3125 |
5338-5339 |
-LRB- |
denotes |
( |
T3126 |
5350-5352 |
NN |
denotes |
os |
T3127 |
5339-5345 |
NN |
denotes |
Figure |
T3128 |
5346-5348 |
NN |
denotes |
4C |
T3129 |
5348-5350 |
, |
denotes |
, |
T3130 |
5352-5353 |
-RRB- |
denotes |
) |
T3131 |
5353-5354 |
. |
denotes |
. |
T3132 |
5354-5493 |
sentence |
denotes |
In Crx-/- retinae, the vast majority of photoreceptors at this stage demonstrated connecting cilia without outer segments (Figure 4D, cc). |
T3133 |
5355-5357 |
IN |
denotes |
In |
T3134 |
5424-5436 |
VBD |
denotes |
demonstrated |
T3135 |
5358-5361 |
NN |
denotes |
Crx |
T3136 |
5365-5372 |
NNS |
denotes |
retinae |
T3137 |
5361-5362 |
SYM |
denotes |
- |
T3138 |
5362-5363 |
HYPH |
denotes |
/ |
T3139 |
5363-5364 |
SYM |
denotes |
- |
T3140 |
5372-5374 |
, |
denotes |
, |
T3141 |
5374-5377 |
DT |
denotes |
the |
T3142 |
5383-5391 |
NN |
denotes |
majority |
T3143 |
5378-5382 |
JJ |
denotes |
vast |
T3144 |
5392-5394 |
IN |
denotes |
of |
T3145 |
5395-5409 |
NNS |
denotes |
photoreceptors |
T3146 |
5410-5412 |
IN |
denotes |
at |
T3147 |
5413-5417 |
DT |
denotes |
this |
T3148 |
5418-5423 |
NN |
denotes |
stage |
T3149 |
5437-5447 |
VBG |
denotes |
connecting |
T3150 |
5448-5453 |
NNS |
denotes |
cilia |
T3151 |
5454-5461 |
IN |
denotes |
without |
T3152 |
5462-5467 |
JJ |
denotes |
outer |
T3153 |
5468-5476 |
NNS |
denotes |
segments |
T3154 |
5477-5478 |
-LRB- |
denotes |
( |
T3155 |
5489-5491 |
NN |
denotes |
cc |
T3156 |
5478-5484 |
NN |
denotes |
Figure |
T3157 |
5485-5487 |
NN |
denotes |
4D |
T3158 |
5487-5489 |
, |
denotes |
, |
T3159 |
5491-5492 |
-RRB- |
denotes |
) |
T3160 |
5492-5493 |
. |
denotes |
. |
T3161 |
5493-5666 |
sentence |
denotes |
Sporadically, Crx-/- photoreceptors would exhibit an irregular structure extending from a connecting cilium (Figure 4D, cc*) perhaps representing a malformed outer segment. |
T3162 |
5494-5506 |
RB |
denotes |
Sporadically |
T3163 |
5536-5543 |
VB |
denotes |
exhibit |
T3164 |
5506-5508 |
, |
denotes |
, |
T3165 |
5508-5511 |
NN |
denotes |
Crx |
T3166 |
5515-5529 |
NNS |
denotes |
photoreceptors |
T3167 |
5511-5512 |
SYM |
denotes |
- |
T3168 |
5512-5513 |
HYPH |
denotes |
/ |
T3169 |
5513-5514 |
SYM |
denotes |
- |
T3170 |
5530-5535 |
MD |
denotes |
would |
T3171 |
5544-5546 |
DT |
denotes |
an |
T3172 |
5557-5566 |
NN |
denotes |
structure |
T3173 |
5547-5556 |
JJ |
denotes |
irregular |
T3174 |
5567-5576 |
VBG |
denotes |
extending |
T3175 |
5577-5581 |
IN |
denotes |
from |
T3176 |
5582-5583 |
DT |
denotes |
a |
T3177 |
5595-5601 |
NN |
denotes |
cilium |
T3178 |
5584-5594 |
VBG |
denotes |
connecting |
T3179 |
5602-5603 |
-LRB- |
denotes |
( |
T3180 |
5614-5617 |
NN |
denotes |
cc* |
T3181 |
5603-5609 |
NN |
denotes |
Figure |
T3182 |
5610-5612 |
NN |
denotes |
4D |
T3183 |
5612-5614 |
, |
denotes |
, |
T3184 |
5617-5618 |
-RRB- |
denotes |
) |
T3185 |
5619-5626 |
RB |
denotes |
perhaps |
T3186 |
5627-5639 |
VBG |
denotes |
representing |
T3187 |
5640-5641 |
DT |
denotes |
a |
T3188 |
5658-5665 |
NN |
denotes |
segment |
T3189 |
5642-5651 |
JJ |
denotes |
malformed |
T3190 |
5652-5657 |
JJ |
denotes |
outer |
T3191 |
5665-5666 |
. |
denotes |
. |
T3192 |
5666-5726 |
sentence |
denotes |
Such structures were also observed at P21 (Figure 4F, cc*). |
T3193 |
5667-5671 |
JJ |
denotes |
Such |
T3194 |
5672-5682 |
NNS |
denotes |
structures |
T3195 |
5693-5701 |
VBN |
denotes |
observed |
T3196 |
5683-5687 |
VBD |
denotes |
were |
T3197 |
5688-5692 |
RB |
denotes |
also |
T3198 |
5702-5704 |
IN |
denotes |
at |
T3199 |
5705-5708 |
NN |
denotes |
P21 |
T3200 |
5709-5710 |
-LRB- |
denotes |
( |
T3201 |
5721-5724 |
NN |
denotes |
cc* |
T3202 |
5710-5716 |
NN |
denotes |
Figure |
T3203 |
5717-5719 |
NN |
denotes |
4F |
T3204 |
5719-5721 |
, |
denotes |
, |
T3205 |
5724-5725 |
-RRB- |
denotes |
) |
T3206 |
5725-5726 |
. |
denotes |
. |
T3207 |
5726-5849 |
sentence |
denotes |
These putative, abnormal outer segments were only rarely noted in Crx+/+ at P14, and never at P21 (Figure 4C and 4E, cc*). |
T3208 |
5727-5732 |
DT |
denotes |
These |
T3209 |
5758-5766 |
NNS |
denotes |
segments |
T3210 |
5733-5741 |
JJ |
denotes |
putative |
T3211 |
5741-5743 |
, |
denotes |
, |
T3212 |
5743-5751 |
JJ |
denotes |
abnormal |
T3213 |
5752-5757 |
JJ |
denotes |
outer |
T3214 |
5784-5789 |
VBN |
denotes |
noted |
T3215 |
5767-5771 |
VBD |
denotes |
were |
T3216 |
5772-5776 |
RB |
denotes |
only |
T3217 |
5777-5783 |
RB |
denotes |
rarely |
T3218 |
5790-5792 |
IN |
denotes |
in |
T3219 |
5793-5796 |
NN |
denotes |
Crx |
T3220 |
5796-5797 |
SYM |
denotes |
+ |
T3221 |
5797-5798 |
HYPH |
denotes |
/ |
T3222 |
5798-5799 |
SYM |
denotes |
+ |
T3223 |
5800-5802 |
IN |
denotes |
at |
T3224 |
5803-5806 |
NN |
denotes |
P14 |
T3225 |
5806-5808 |
, |
denotes |
, |
T3226 |
5808-5811 |
CC |
denotes |
and |
T3227 |
5812-5817 |
RB |
denotes |
never |
T3228 |
5818-5820 |
IN |
denotes |
at |
T3229 |
5821-5824 |
NN |
denotes |
P21 |
T3230 |
5825-5826 |
-LRB- |
denotes |
( |
T3231 |
5844-5846 |
NN |
denotes |
cc |
T3232 |
5826-5832 |
NN |
denotes |
Figure |
T3233 |
5833-5835 |
NN |
denotes |
4C |
T3234 |
5836-5839 |
CC |
denotes |
and |
T3235 |
5840-5842 |
NN |
denotes |
4E |
T3236 |
5842-5844 |
, |
denotes |
, |
T3237 |
5846-5847 |
SYM |
denotes |
* |
T3238 |
5847-5848 |
-RRB- |
denotes |
) |
T3239 |
5848-5849 |
. |
denotes |
. |
T3240 |
5849-5944 |
sentence |
denotes |
Further, in Crx-/- photoreceptors, unusually long connecting cilia were noted (Figure 4F, cc). |
T3241 |
5850-5857 |
RB |
denotes |
Further |
T3242 |
5922-5927 |
VBN |
denotes |
noted |
T3243 |
5857-5859 |
, |
denotes |
, |
T3244 |
5859-5861 |
IN |
denotes |
in |
T3245 |
5862-5865 |
NN |
denotes |
Crx |
T3246 |
5869-5883 |
NNS |
denotes |
photoreceptors |
T3247 |
5865-5866 |
SYM |
denotes |
- |
T3248 |
5866-5867 |
HYPH |
denotes |
/ |
T3249 |
5867-5868 |
SYM |
denotes |
- |
T3250 |
5883-5885 |
, |
denotes |
, |
T3251 |
5885-5894 |
RB |
denotes |
unusually |
T3252 |
5895-5899 |
JJ |
denotes |
long |
T3253 |
5911-5916 |
NNS |
denotes |
cilia |
T3254 |
5900-5910 |
VBG |
denotes |
connecting |
T3255 |
5917-5921 |
VBD |
denotes |
were |
T3256 |
5928-5929 |
-LRB- |
denotes |
( |
T3257 |
5940-5942 |
NN |
denotes |
cc |
T3276 |
5996-5999 |
NN |
denotes |
P10 |
T3277 |
5999-6001 |
, |
denotes |
, |
T3278 |
6001-6004 |
NN |
denotes |
P14 |
T3279 |
6004-6006 |
, |
denotes |
, |
T3280 |
6006-6009 |
CC |
denotes |
and |
T3281 |
6010-6013 |
NN |
denotes |
P21 |
T3282 |
6014-6016 |
IN |
denotes |
by |
T3283 |
6017-6020 |
NN |
denotes |
TEM |
T3284 |
6020-6022 |
, |
denotes |
, |
T3285 |
6035-6036 |
DT |
denotes |
a |
T3286 |
6049-6053 |
NN |
denotes |
lack |
T3287 |
6037-6048 |
JJ |
denotes |
distinctive |
T3288 |
6054-6056 |
IN |
denotes |
of |
T3289 |
6057-6060 |
DT |
denotes |
any |
T3290 |
6061-6070 |
NN |
denotes |
structure |
T3291 |
6071-6084 |
JJ |
denotes |
interpretable |
T3292 |
6085-6087 |
IN |
denotes |
as |
T3293 |
6088-6095 |
JJ |
denotes |
orderly |
T3294 |
6096-6102 |
NNS |
denotes |
stacks |
T3295 |
6103-6105 |
IN |
denotes |
of |
T3296 |
6106-6111 |
NNS |
denotes |
discs |
T3297 |
6112-6114 |
CC |
denotes |
or |
T3298 |
6115-6122 |
VBG |
denotes |
forming |
T3299 |
6123-6128 |
NNS |
denotes |
discs |
T3300 |
6128-6129 |
. |
denotes |
. |
T3301 |
6129-6343 |
sentence |
denotes |
These data demonstrate a complete absence of normal outer segment formation in the Crx mutant mouse, and the arrest of development of the photoreceptor appendage at the elongation stage of outer segment formation. |
T3302 |
6130-6135 |
DT |
denotes |
These |
T3303 |
6136-6140 |
NNS |
denotes |
data |
T3304 |
6141-6152 |
VBP |
denotes |
demonstrate |
T3305 |
6153-6154 |
DT |
denotes |
a |
T3306 |
6164-6171 |
NN |
denotes |
absence |
T3307 |
6155-6163 |
JJ |
denotes |
complete |
T3308 |
6172-6174 |
IN |
denotes |
of |
T3309 |
6175-6181 |
JJ |
denotes |
normal |
T3310 |
6196-6205 |
NN |
denotes |
formation |
T3311 |
6182-6187 |
JJ |
denotes |
outer |
T3312 |
6188-6195 |
NN |
denotes |
segment |
T3313 |
6206-6208 |
IN |
denotes |
in |
T3314 |
6209-6212 |
DT |
denotes |
the |
T3315 |
6224-6229 |
NN |
denotes |
mouse |
T3316 |
6213-6216 |
NN |
denotes |
Crx |
T3317 |
6217-6223 |
NN |
denotes |
mutant |
T3318 |
6229-6231 |
, |
denotes |
, |
T3319 |
6231-6234 |
CC |
denotes |
and |
T3320 |
6235-6238 |
DT |
denotes |
the |
T3321 |
6239-6245 |
NN |
denotes |
arrest |
T3322 |
6246-6248 |
IN |
denotes |
of |
T3323 |
6249-6260 |
NN |
denotes |
development |
T3324 |
6261-6263 |
IN |
denotes |
of |
T3325 |
6264-6267 |
DT |
denotes |
the |
T3326 |
6282-6291 |
NN |
denotes |
appendage |
T3327 |
6268-6281 |
NN |
denotes |
photoreceptor |
T3328 |
6292-6294 |
IN |
denotes |
at |
T3329 |
6295-6298 |
DT |
denotes |
the |
T3330 |
6310-6315 |
NN |
denotes |
stage |
T3331 |
6299-6309 |
NN |
denotes |
elongation |
T3332 |
6316-6318 |
IN |
denotes |
of |
T3333 |
6319-6324 |
JJ |
denotes |
outer |
T3334 |
6325-6332 |
NN |
denotes |
segment |
T3335 |
6333-6342 |
NN |
denotes |
formation |
T3336 |
6342-6343 |
. |
denotes |
. |
T3337 |
6343-6346 |
sentence |
denotes |
Fi |
T3338 |
6344-6346 |
NN |
denotes |
Fi |
T3339 |
7649-7650 |
sentence |
denotes |
n |
T3340 |
7649-7650 |
NN |
denotes |
n |
T3341 |
7650-7653 |
sentence |
denotes |
all |
T3342 |
7650-7651 |
VBG |
denotes |
a |
T3343 |
7651-7652 |
NN |
denotes |
l |
T3344 |
7652-7653 |
VBG |
denotes |
l |
T3388 |
7773-7782 |
NN |
denotes |
Rhodopsin |
T3389 |
7798-7801 |
VBP |
denotes |
are |
T3390 |
7783-7786 |
CC |
denotes |
and |
T3391 |
7787-7797 |
NN |
denotes |
peripherin |
T3392 |
7802-7805 |
CD |
denotes |
two |
T3393 |
7829-7834 |
NNS |
denotes |
genes |
T3394 |
7806-7819 |
NN |
denotes |
photoreceptor |
T3395 |
7820-7828 |
JJ |
denotes |
specific |
T3396 |
7819-7820 |
HYPH |
denotes |
- |
T3397 |
7835-7840 |
WP$ |
denotes |
whose |
T3398 |
7841-7851 |
NN |
denotes |
expression |
T3399 |
7869-7882 |
VBN |
denotes |
downregulated |
T3400 |
7852-7854 |
VBZ |
denotes |
is |
T3401 |
7855-7868 |
RB |
denotes |
significantly |
T3402 |
7883-7885 |
IN |
denotes |
in |
T3403 |
7886-7889 |
DT |
denotes |
the |
T3404 |
7897-7904 |
NNS |
denotes |
retinae |
T3405 |
7890-7893 |
NN |
denotes |
Crx |
T3406 |
7893-7894 |
SYM |
denotes |
- |
T3407 |
7894-7895 |
HYPH |
denotes |
/ |
T3408 |
7895-7896 |
SYM |
denotes |
- |
T3409 |
7905-7906 |
-LRB- |
denotes |
[ |
T3410 |
7912-7914 |
CD |
denotes |
35 |
T3411 |
7906-7908 |
CD |
denotes |
10 |
T3412 |
7908-7909 |
, |
denotes |
, |
T3413 |
7909-7911 |
CD |
denotes |
34 |
T3414 |
7911-7912 |
, |
denotes |
, |
T3415 |
7914-7915 |
-RRB- |
denotes |
] |
T3416 |
7915-7916 |
. |
denotes |
. |
T3417 |
7916-8056 |
sentence |
denotes |
Loss of function mutations in each of these genes separately have been reported to result in a failure to elaborate outer segments [29,30]. |
T3418 |
7917-7921 |
NN |
denotes |
Loss |
T3419 |
7934-7943 |
NNS |
denotes |
mutations |
T3420 |
7922-7924 |
IN |
denotes |
of |
T3421 |
7925-7933 |
NN |
denotes |
function |
T3422 |
7988-7996 |
VBN |
denotes |
reported |
T3423 |
7944-7946 |
IN |
denotes |
in |
T3424 |
7947-7951 |
DT |
denotes |
each |
T3425 |
7952-7954 |
IN |
denotes |
of |
T3426 |
7955-7960 |
DT |
denotes |
these |
T3427 |
7961-7966 |
NNS |
denotes |
genes |
T3428 |
7967-7977 |
RB |
denotes |
separately |
T3429 |
7978-7982 |
VBP |
denotes |
have |
T3430 |
7983-7987 |
VBN |
denotes |
been |
T3431 |
7997-7999 |
TO |
denotes |
to |
T3432 |
8000-8006 |
VB |
denotes |
result |
T3433 |
8007-8009 |
IN |
denotes |
in |
T3434 |
8010-8011 |
DT |
denotes |
a |
T3435 |
8012-8019 |
NN |
denotes |
failure |
T3436 |
8020-8022 |
TO |
denotes |
to |
T3437 |
8023-8032 |
VB |
denotes |
elaborate |
T3438 |
8033-8038 |
JJ |
denotes |
outer |
T3439 |
8039-8047 |
NNS |
denotes |
segments |
T3440 |
8048-8049 |
-LRB- |
denotes |
[ |
T3441 |
8052-8054 |
CD |
denotes |
30 |
T3442 |
8049-8051 |
CD |
denotes |
29 |
T3443 |
8051-8052 |
, |
denotes |
, |
T3444 |
8054-8055 |
-RRB- |
denotes |
] |
T3445 |
8055-8056 |
. |
denotes |
. |
T3446 |
8056-8226 |
sentence |
denotes |
Photoreceptors from these two mutant mice examined by SEM from the scleral side appeared highly similar to Crx-/- photoreceptors (compare Figure 4F to Figure 6A and 6B). |
T3447 |
8057-8071 |
NNS |
denotes |
Photoreceptors |
T3448 |
8137-8145 |
VBD |
denotes |
appeared |
T3449 |
8072-8076 |
IN |
denotes |
from |
T3450 |
8077-8082 |
DT |
denotes |
these |
T3451 |
8094-8098 |
NNS |
denotes |
mice |
T3452 |
8083-8086 |
CD |
denotes |
two |
T3453 |
8087-8093 |
JJ |
denotes |
mutant |
T3454 |
8099-8107 |
VBN |
denotes |
examined |
T3455 |
8108-8110 |
IN |
denotes |
by |
T3456 |
8111-8114 |
NN |
denotes |
SEM |
T3457 |
8115-8119 |
IN |
denotes |
from |
T3458 |
8120-8123 |
DT |
denotes |
the |
T3459 |
8132-8136 |
NN |
denotes |
side |
T3460 |
8124-8131 |
JJ |
denotes |
scleral |
T3461 |
8146-8152 |
RB |
denotes |
highly |
T3462 |
8153-8160 |
JJ |
denotes |
similar |
T3463 |
8161-8163 |
IN |
denotes |
to |
T3464 |
8164-8167 |
NN |
denotes |
Crx |
T3465 |
8171-8185 |
NNS |
denotes |
photoreceptors |
T3466 |
8167-8168 |
SYM |
denotes |
- |
T3467 |
8168-8169 |
HYPH |
denotes |
/ |
T3468 |
8169-8170 |
SYM |
denotes |
- |
T3469 |
8186-8187 |
-LRB- |
denotes |
( |
T3470 |
8187-8194 |
VB |
denotes |
compare |
T3471 |
8195-8201 |
NN |
denotes |
Figure |
T3472 |
8202-8204 |
NN |
denotes |
4F |
T3473 |
8205-8207 |
IN |
denotes |
to |
T3474 |
8208-8214 |
NN |
denotes |
Figure |
T3475 |
8215-8217 |
NN |
denotes |
6A |
T3476 |
8218-8221 |
CC |
denotes |
and |
T3477 |
8222-8224 |
NN |
denotes |
6B |
T3478 |
8224-8225 |
-RRB- |
denotes |
) |
T3479 |
8225-8226 |
. |
denotes |
. |
T3638 |
8461-8464 |
NN |
denotes |
Crx |
T3639 |
8465-8467 |
VBZ |
denotes |
is |
T3640 |
8468-8477 |
JJ |
denotes |
necessary |
T3641 |
8478-8481 |
IN |
denotes |
for |
T3642 |
8482-8485 |
DT |
denotes |
the |
T3643 |
8486-8495 |
NN |
denotes |
formation |
T3644 |
8496-8498 |
IN |
denotes |
of |
T3645 |
8499-8512 |
NN |
denotes |
photoreceptor |
T3646 |
8513-8522 |
NNS |
denotes |
terminals |
T3647 |
8522-8737 |
sentence |
denotes |
In a previous study, we demonstrated that forced expression of a dominant-negative allele of Crx in developing rods blocked formation of both rod spherules in the outer plexiform layer (OPL) and outer segments [7]. |
T3648 |
8523-8525 |
IN |
denotes |
In |
T3649 |
8547-8559 |
VBD |
denotes |
demonstrated |
T3650 |
8526-8527 |
DT |
denotes |
a |
T3651 |
8537-8542 |
NN |
denotes |
study |
T3652 |
8528-8536 |
JJ |
denotes |
previous |
T3653 |
8542-8544 |
, |
denotes |
, |
T3654 |
8544-8546 |
PRP |
denotes |
we |
T3655 |
8560-8564 |
IN |
denotes |
that |
T3656 |
8639-8646 |
VBD |
denotes |
blocked |
T3657 |
8565-8571 |
VBN |
denotes |
forced |
T3658 |
8572-8582 |
NN |
denotes |
expression |
T3659 |
8583-8585 |
IN |
denotes |
of |
T3660 |
8586-8587 |
DT |
denotes |
a |
T3661 |
8606-8612 |
NN |
denotes |
allele |
T3662 |
8588-8596 |
JJ |
denotes |
dominant |
T3663 |
8597-8605 |
JJ |
denotes |
negative |
T3664 |
8596-8597 |
HYPH |
denotes |
- |
T3665 |
8613-8615 |
IN |
denotes |
of |
T3666 |
8616-8619 |
NN |
denotes |
Crx |
T3667 |
8620-8622 |
IN |
denotes |
in |
T3668 |
8623-8633 |
VBG |
denotes |
developing |
T3669 |
8634-8638 |
NNS |
denotes |
rods |
T3670 |
8647-8656 |
NN |
denotes |
formation |
T3671 |
8657-8659 |
IN |
denotes |
of |
T3672 |
8660-8664 |
DT |
denotes |
both |
T3673 |
8669-8678 |
NNS |
denotes |
spherules |
T3674 |
8665-8668 |
NN |
denotes |
rod |
T3675 |
8679-8681 |
IN |
denotes |
in |
T3676 |
8682-8685 |
DT |
denotes |
the |
T3677 |
8702-8707 |
NN |
denotes |
layer |
T3678 |
8686-8691 |
JJ |
denotes |
outer |
T3679 |
8692-8701 |
NN |
denotes |
plexiform |
T3680 |
8708-8709 |
-LRB- |
denotes |
( |
T3681 |
8709-8712 |
NN |
denotes |
OPL |
T3682 |
8712-8713 |
-RRB- |
denotes |
) |
T3683 |
8714-8717 |
CC |
denotes |
and |
T3684 |
8718-8723 |
JJ |
denotes |
outer |
T3685 |
8724-8732 |
NNS |
denotes |
segments |
T3686 |
8733-8734 |
-LRB- |
denotes |
[ |
T3687 |
8734-8735 |
CD |
denotes |
7 |
T3688 |
8735-8736 |
-RRB- |
denotes |
] |
T3689 |
8736-8737 |
. |
denotes |
. |
T3690 |
8737-8842 |
sentence |
denotes |
To expand on these studies, the ultrastructure of photoreceptor synapses was examined in Crx-/- retinas. |
T3691 |
8738-8740 |
TO |
denotes |
To |
T3692 |
8741-8747 |
VB |
denotes |
expand |
T3693 |
8815-8823 |
VBN |
denotes |
examined |
T3694 |
8748-8750 |
IN |
denotes |
on |
T3695 |
8751-8756 |
DT |
denotes |
these |
T3696 |
8757-8764 |
NNS |
denotes |
studies |
T3697 |
8764-8766 |
, |
denotes |
, |
T3698 |
8766-8769 |
DT |
denotes |
the |
T3699 |
8770-8784 |
NN |
denotes |
ultrastructure |
T3700 |
8785-8787 |
IN |
denotes |
of |
T3701 |
8788-8801 |
NN |
denotes |
photoreceptor |
T3702 |
8802-8810 |
NNS |
denotes |
synapses |
T3703 |
8811-8814 |
VBD |
denotes |
was |
T3704 |
8824-8826 |
IN |
denotes |
in |
T3705 |
8827-8830 |
NN |
denotes |
Crx |
T3706 |
8834-8841 |
NNS |
denotes |
retinas |
T3707 |
8830-8831 |
SYM |
denotes |
- |
T3708 |
8831-8832 |
HYPH |
denotes |
/ |
T3709 |
8832-8833 |
SYM |
denotes |
- |
T3710 |
8841-8842 |
. |
denotes |
. |
T3711 |
8842-8922 |
sentence |
denotes |
In Crx+/+ retinas at P21, newly mature rod spherules were abundant (Figure 7A). |
T3712 |
8843-8845 |
IN |
denotes |
In |
T3713 |
8896-8900 |
VBD |
denotes |
were |
T3714 |
8846-8849 |
NN |
denotes |
Crx |
T3715 |
8853-8860 |
NNS |
denotes |
retinas |
T3716 |
8849-8850 |
SYM |
denotes |
+ |
T3717 |
8850-8851 |
HYPH |
denotes |
/ |
T3718 |
8851-8852 |
SYM |
denotes |
+ |
T3719 |
8861-8863 |
IN |
denotes |
at |
T3720 |
8864-8867 |
NN |
denotes |
P21 |
T3721 |
8867-8869 |
, |
denotes |
, |
T3722 |
8869-8874 |
RB |
denotes |
newly |
T3723 |
8875-8881 |
JJ |
denotes |
mature |
T3724 |
8886-8895 |
NNS |
denotes |
spherules |
T3725 |
8882-8885 |
NN |
denotes |
rod |
T3726 |
8901-8909 |
JJ |
denotes |
abundant |
T3727 |
8910-8911 |
-LRB- |
denotes |
( |
T3728 |
8918-8920 |
NN |
denotes |
7A |
T3729 |
8911-8917 |
NN |
denotes |
Figure |
T3730 |
8920-8921 |
-RRB- |
denotes |
) |
T3731 |
8921-8922 |
. |
denotes |
. |
T3732 |
8922-9099 |
sentence |
denotes |
The sperules were blunt or club-shaped structures with a single ribbon associated with a single invaginating synapse (Figure 7A, arrow indicates one example; Figure 8A and 8B). |
T3733 |
8923-8926 |
DT |
denotes |
The |
T3734 |
8927-8935 |
NNS |
denotes |
sperules |
T3735 |
8936-8940 |
VBD |
denotes |
were |
T3736 |
8941-8946 |
JJ |
denotes |
blunt |
T3737 |
8962-8972 |
NNS |
denotes |
structures |
T3738 |
8947-8949 |
CC |
denotes |
or |
T3739 |
8950-8954 |
NN |
denotes |
club |
T3740 |
8955-8961 |
VBN |
denotes |
shaped |
T3741 |
8954-8955 |
HYPH |
denotes |
- |
T3742 |
8973-8977 |
IN |
denotes |
with |
T3743 |
8978-8979 |
DT |
denotes |
a |
T3744 |
8987-8993 |
NN |
denotes |
ribbon |
T3745 |
8980-8986 |
JJ |
denotes |
single |
T3746 |
8994-9004 |
VBN |
denotes |
associated |
T3747 |
9005-9009 |
IN |
denotes |
with |
T3748 |
9010-9011 |
DT |
denotes |
a |
T3749 |
9032-9039 |
NN |
denotes |
synapse |
T3750 |
9012-9018 |
JJ |
denotes |
single |
T3751 |
9019-9031 |
VBG |
denotes |
invaginating |
T3752 |
9040-9041 |
-LRB- |
denotes |
( |
T3753 |
9088-9090 |
NN |
denotes |
8A |
T3754 |
9041-9047 |
NN |
denotes |
Figure |
T3755 |
9048-9050 |
NN |
denotes |
7A |
T3756 |
9050-9052 |
, |
denotes |
, |
T3757 |
9052-9057 |
NN |
denotes |
arrow |
T3758 |
9058-9067 |
VBZ |
denotes |
indicates |
T3759 |
9068-9071 |
CD |
denotes |
one |
T3760 |
9072-9079 |
NN |
denotes |
example |
T3761 |
9079-9080 |
: |
denotes |
; |
T3762 |
9081-9087 |
NN |
denotes |
Figure |
T3763 |
9091-9094 |
CC |
denotes |
and |
T3764 |
9095-9097 |
NN |
denotes |
8B |
T3765 |
9097-9098 |
-RRB- |
denotes |
) |
T3766 |
9098-9099 |
. |
denotes |
. |
T3767 |
9099-9318 |
sentence |
denotes |
Two processes from horizontal cells were situated on either side of the synaptic ridge (Figure 8B, labelled H) and one or more dendrites of rod bipolar cells occupied a central position (Figure 8B, bipolar labelled B). |
T3768 |
9100-9103 |
CD |
denotes |
Two |
T3769 |
9104-9113 |
NNS |
denotes |
processes |
T3770 |
9141-9149 |
VBN |
denotes |
situated |
T3771 |
9114-9118 |
IN |
denotes |
from |
T3772 |
9119-9129 |
JJ |
denotes |
horizontal |
T3773 |
9130-9135 |
NNS |
denotes |
cells |
T3774 |
9136-9140 |
VBD |
denotes |
were |
T3775 |
9150-9152 |
IN |
denotes |
on |
T3776 |
9153-9159 |
DT |
denotes |
either |
T3777 |
9160-9164 |
NN |
denotes |
side |
T3778 |
9165-9167 |
IN |
denotes |
of |
T3779 |
9168-9171 |
DT |
denotes |
the |
T3780 |
9181-9186 |
NN |
denotes |
ridge |
T3781 |
9172-9180 |
JJ |
denotes |
synaptic |
T3782 |
9187-9188 |
-LRB- |
denotes |
( |
T3783 |
9195-9197 |
NN |
denotes |
8B |
T3784 |
9188-9194 |
NN |
denotes |
Figure |
T3785 |
9197-9199 |
, |
denotes |
, |
T3786 |
9199-9207 |
VBN |
denotes |
labelled |
T3787 |
9208-9209 |
NN |
denotes |
H |
T3788 |
9209-9210 |
-RRB- |
denotes |
) |
T3789 |
9211-9214 |
CC |
denotes |
and |
T3790 |
9215-9218 |
CD |
denotes |
one |
T3791 |
9227-9236 |
NNS |
denotes |
dendrites |
T3792 |
9219-9221 |
CC |
denotes |
or |
T3793 |
9222-9226 |
JJR |
denotes |
more |
T3794 |
9258-9266 |
VBD |
denotes |
occupied |
T3795 |
9237-9239 |
IN |
denotes |
of |
T3796 |
9240-9243 |
NN |
denotes |
rod |
T3797 |
9252-9257 |
NNS |
denotes |
cells |
T3798 |
9244-9251 |
JJ |
denotes |
bipolar |
T3799 |
9267-9268 |
DT |
denotes |
a |
T3800 |
9277-9285 |
NN |
denotes |
position |
T3801 |
9269-9276 |
JJ |
denotes |
central |
T3802 |
9286-9287 |
-LRB- |
denotes |
( |
T3803 |
9315-9316 |
NN |
denotes |
B |
T3804 |
9287-9293 |
NN |
denotes |
Figure |
T3805 |
9294-9296 |
NN |
denotes |
8B |
T3806 |
9296-9298 |
, |
denotes |
, |
T3807 |
9298-9305 |
JJ |
denotes |
bipolar |
T3808 |
9306-9314 |
VBN |
denotes |
labelled |
T3809 |
9316-9317 |
-RRB- |
denotes |
) |
T3810 |
9317-9318 |
. |
denotes |
. |
T3811 |
9318-9465 |
sentence |
denotes |
Cone terminals are large, flat pedicles that exhibit many invaginating synapses containing separate sets of horizontal and bipolar cell processes. |
T3812 |
9319-9323 |
NN |
denotes |
Cone |
T3813 |
9324-9333 |
NNS |
denotes |
terminals |
T3814 |
9334-9337 |
VBP |
denotes |
are |
T3815 |
9338-9343 |
JJ |
denotes |
large |
T3816 |
9345-9349 |
JJ |
denotes |
flat |
T3817 |
9343-9345 |
, |
denotes |
, |
T3818 |
9350-9358 |
NNS |
denotes |
pedicles |
T3819 |
9359-9363 |
WDT |
denotes |
that |
T3820 |
9364-9371 |
VBP |
denotes |
exhibit |
T3821 |
9372-9376 |
JJ |
denotes |
many |
T3822 |
9390-9398 |
NNS |
denotes |
synapses |
T3823 |
9377-9389 |
VBG |
denotes |
invaginating |
T3824 |
9399-9409 |
VBG |
denotes |
containing |
T3825 |
9410-9418 |
JJ |
denotes |
separate |
T3826 |
9419-9423 |
NNS |
denotes |
sets |
T3827 |
9424-9426 |
IN |
denotes |
of |
T3828 |
9427-9437 |
JJ |
denotes |
horizontal |
T3829 |
9455-9464 |
NNS |
denotes |
processes |
T3830 |
9438-9441 |
CC |
denotes |
and |
T3831 |
9442-9449 |
JJ |
denotes |
bipolar |
T3832 |
9450-9454 |
NN |
denotes |
cell |
T3833 |
9464-9465 |
. |
denotes |
. |
T3834 |
9465-9505 |
sentence |
denotes |
Each pedicle contains numerous ribbons. |
T3835 |
9466-9470 |
DT |
denotes |
Each |
T3836 |
9471-9478 |
NN |
denotes |
pedicle |
T3837 |
9479-9487 |
VBZ |
denotes |
contains |
T3838 |
9488-9496 |
JJ |
denotes |
numerous |
T3839 |
9497-9504 |
NNS |
denotes |
ribbons |
T3840 |
9504-9505 |
. |
denotes |
. |
T3841 |
9505-9600 |
sentence |
denotes |
These terminals were much less common than spherules in Crx+/+ retinas at P21 (Figure 7, box). |
T3842 |
9506-9511 |
DT |
denotes |
These |
T3843 |
9512-9521 |
NNS |
denotes |
terminals |
T3844 |
9522-9526 |
VBD |
denotes |
were |
T3845 |
9527-9531 |
RB |
denotes |
much |
T3846 |
9532-9536 |
RBR |
denotes |
less |
T3847 |
9537-9543 |
JJ |
denotes |
common |
T3848 |
9544-9548 |
IN |
denotes |
than |
T3849 |
9549-9558 |
NNS |
denotes |
spherules |
T3850 |
9559-9561 |
IN |
denotes |
in |
T3851 |
9562-9565 |
NN |
denotes |
Crx |
T3852 |
9569-9576 |
NNS |
denotes |
retinas |
T3853 |
9565-9566 |
SYM |
denotes |
+ |
T3854 |
9566-9567 |
HYPH |
denotes |
/ |
T3855 |
9567-9568 |
SYM |
denotes |
+ |
T3856 |
9577-9579 |
IN |
denotes |
at |
T3857 |
9580-9583 |
NN |
denotes |
P21 |
T3858 |
9584-9585 |
-LRB- |
denotes |
( |
T3859 |
9595-9598 |
NN |
denotes |
box |
T3860 |
9585-9591 |
NN |
denotes |
Figure |
T3861 |
9592-9593 |
CD |
denotes |
7 |
T3862 |
9593-9595 |
, |
denotes |
, |
T3863 |
9598-9599 |
-RRB- |
denotes |
) |
T3864 |
9599-9600 |
. |
denotes |
. |
T3865 |
9600-9707 |
sentence |
denotes |
In the OPL of Crx-/- retinas, photoreceptor terminals were highly disorganized at P21 (Figure 7B, arrows). |
T3866 |
9601-9603 |
IN |
denotes |
In |
T3867 |
9655-9659 |
VBD |
denotes |
were |
T3868 |
9604-9607 |
DT |
denotes |
the |
T3869 |
9608-9611 |
NN |
denotes |
OPL |
T3870 |
9612-9614 |
IN |
denotes |
of |
T3871 |
9615-9618 |
NN |
denotes |
Crx |
T3872 |
9622-9629 |
NNS |
denotes |
retinas |
T3873 |
9618-9619 |
SYM |
denotes |
- |
T3874 |
9619-9620 |
HYPH |
denotes |
/ |
T3875 |
9620-9621 |
SYM |
denotes |
- |
T3876 |
9629-9631 |
, |
denotes |
, |
T3877 |
9631-9644 |
NN |
denotes |
photoreceptor |
T3878 |
9645-9654 |
NNS |
denotes |
terminals |
T3879 |
9660-9666 |
RB |
denotes |
highly |
T3880 |
9667-9679 |
JJ |
denotes |
disorganized |
T3881 |
9680-9682 |
IN |
denotes |
at |
T3882 |
9683-9686 |
NN |
denotes |
P21 |
T3883 |
9687-9688 |
-LRB- |
denotes |
( |
T3884 |
9699-9705 |
NNS |
denotes |
arrows |
T3885 |
9688-9694 |
NN |
denotes |
Figure |
T3886 |
9695-9697 |
NN |
denotes |
7B |
T3887 |
9697-9699 |
, |
denotes |
, |
T3888 |
9705-9706 |
-RRB- |
denotes |
) |
T3889 |
9706-9707 |
. |
denotes |
. |
T3890 |
9707-9850 |
sentence |
denotes |
Processes containing synaptic vesicles and ribbon-like structures were apparent, suggesting at least limited generation of synapse components. |
T3891 |
9708-9717 |
NNS |
denotes |
Processes |
T3892 |
9774-9778 |
VBD |
denotes |
were |
T3893 |
9718-9728 |
VBG |
denotes |
containing |
T3894 |
9729-9737 |
JJ |
denotes |
synaptic |
T3895 |
9738-9746 |
NNS |
denotes |
vesicles |
T3896 |
9747-9750 |
CC |
denotes |
and |
T3897 |
9751-9757 |
NN |
denotes |
ribbon |
T3898 |
9758-9762 |
JJ |
denotes |
like |
T3899 |
9757-9758 |
HYPH |
denotes |
- |
T3900 |
9763-9773 |
NNS |
denotes |
structures |
T3901 |
9779-9787 |
JJ |
denotes |
apparent |
T3902 |
9787-9789 |
, |
denotes |
, |
T3903 |
9789-9799 |
VBG |
denotes |
suggesting |
T3904 |
9800-9802 |
RB |
denotes |
at |
T3905 |
9803-9808 |
RBS |
denotes |
least |
T3906 |
9809-9816 |
JJ |
denotes |
limited |
T3907 |
9817-9827 |
NN |
denotes |
generation |
T3908 |
9828-9830 |
IN |
denotes |
of |
T3909 |
9831-9838 |
NN |
denotes |
synapse |
T3910 |
9839-9849 |
NNS |
denotes |
components |
T3911 |
9849-9850 |
. |
denotes |
. |
T3912 |
9850-9913 |
sentence |
denotes |
However, well formed spherules and pedicles were not observed. |
T3913 |
9851-9858 |
RB |
denotes |
However |
T3914 |
9904-9912 |
VBN |
denotes |
observed |
T3915 |
9858-9860 |
, |
denotes |
, |
T3916 |
9860-9864 |
RB |
denotes |
well |
T3917 |
9865-9871 |
VBN |
denotes |
formed |
T3918 |
9872-9881 |
NNS |
denotes |
spherules |
T3919 |
9882-9885 |
CC |
denotes |
and |
T3920 |
9886-9894 |
NNS |
denotes |
pedicles |
T3921 |
9895-9899 |
VBD |
denotes |
were |
T3922 |
9900-9903 |
RB |
denotes |
not |
T3923 |
9912-9913 |
. |
denotes |
. |
T3924 |
9913-10091 |
sentence |
denotes |
In addition, many terminals appeared to contain multiple ribbons (Figure 8C and 8D, r) not tethered to the plasma membrane and occasionally in perinuclear positions (Figure 8D). |
T3925 |
9914-9916 |
IN |
denotes |
In |
T3926 |
9942-9950 |
VBD |
denotes |
appeared |
T3927 |
9917-9925 |
NN |
denotes |
addition |
T3928 |
9925-9927 |
, |
denotes |
, |
T3929 |
9927-9931 |
JJ |
denotes |
many |
T3930 |
9932-9941 |
NNS |
denotes |
terminals |
T3931 |
9951-9953 |
TO |
denotes |
to |
T3932 |
9954-9961 |
VB |
denotes |
contain |
T3933 |
9962-9970 |
JJ |
denotes |
multiple |
T3934 |
9971-9978 |
NNS |
denotes |
ribbons |
T3935 |
9979-9980 |
-LRB- |
denotes |
( |
T3936 |
9998-9999 |
NN |
denotes |
r |
T3937 |
9980-9986 |
NN |
denotes |
Figure |
T3938 |
9987-9989 |
NN |
denotes |
8C |
T3939 |
9990-9993 |
CC |
denotes |
and |
T3940 |
9994-9996 |
NN |
denotes |
8D |
T3941 |
9996-9998 |
, |
denotes |
, |
T3942 |
9999-10000 |
-RRB- |
denotes |
) |
T3943 |
10001-10004 |
RB |
denotes |
not |
T3944 |
10005-10013 |
VBN |
denotes |
tethered |
T3945 |
10014-10016 |
IN |
denotes |
to |
T3946 |
10017-10020 |
DT |
denotes |
the |
T3947 |
10028-10036 |
NN |
denotes |
membrane |
T3948 |
10021-10027 |
NN |
denotes |
plasma |
T3949 |
10037-10040 |
CC |
denotes |
and |
T3950 |
10041-10053 |
RB |
denotes |
occasionally |
T3951 |
10054-10056 |
IN |
denotes |
in |
T3952 |
10057-10068 |
JJ |
denotes |
perinuclear |
T3953 |
10069-10078 |
NNS |
denotes |
positions |
T3954 |
10079-10080 |
-LRB- |
denotes |
( |
T3955 |
10087-10089 |
NN |
denotes |
8D |
T3956 |
10080-10086 |
NN |
denotes |
Figure |
T3957 |
10089-10090 |
-RRB- |
denotes |
) |
T3958 |
10090-10091 |
. |
denotes |
. |
T8250 |
1103-1115 |
NN |
denotes |
Transmission |
T8251 |
1125-1135 |
NN |
denotes |
microscopy |
T8252 |
1116-1124 |
NN |
denotes |
electron |
T8253 |
1136-1138 |
IN |
denotes |
of |
T8254 |
1139-1142 |
DT |
denotes |
the |
T8255 |
1149-1155 |
NN |
denotes |
retina |
T8256 |
1143-1148 |
JJ |
denotes |
outer |
T8257 |
1156-1158 |
IN |
denotes |
at |
T8258 |
1159-1162 |
NN |
denotes |
P21 |
T8259 |
1163-1165 |
IN |
denotes |
in |
T8260 |
1166-1167 |
-LRB- |
denotes |
( |
T8261 |
1167-1168 |
LS |
denotes |
A |
T8262 |
1170-1173 |
NN |
denotes |
Crx |
T8263 |
1168-1169 |
-RRB- |
denotes |
) |
T8264 |
1192-1199 |
NNS |
denotes |
retinas |
T8265 |
1173-1174 |
SYM |
denotes |
+ |
T8266 |
1174-1175 |
HYPH |
denotes |
/ |
T8267 |
1175-1176 |
SYM |
denotes |
+ |
T8268 |
1177-1180 |
CC |
denotes |
and |
T8269 |
1181-1182 |
-LRB- |
denotes |
( |
T8270 |
1182-1183 |
LS |
denotes |
B |
T8271 |
1185-1188 |
NN |
denotes |
Crx |
T8272 |
1183-1184 |
-RRB- |
denotes |
) |
T8273 |
1188-1189 |
SYM |
denotes |
- |
T8274 |
1189-1190 |
HYPH |
denotes |
/ |
T8275 |
1190-1191 |
SYM |
denotes |
- |
T8276 |
1199-1200 |
. |
denotes |
. |
T8277 |
1200-1226 |
sentence |
denotes |
pe, pigmented epithelium. |
T8278 |
1201-1203 |
NN |
denotes |
pe |
T8279 |
1203-1205 |
, |
denotes |
, |
T8280 |
1205-1214 |
JJ |
denotes |
pigmented |
T8281 |
1215-1225 |
NN |
denotes |
epithelium |
T8282 |
1225-1226 |
. |
denotes |
. |
T8283 |
1226-1246 |
sentence |
denotes |
os, outer segments. |
T8284 |
1227-1229 |
NN |
denotes |
os |
T8285 |
1229-1231 |
, |
denotes |
, |
T8286 |
1231-1236 |
JJ |
denotes |
outer |
T8287 |
1237-1245 |
NNS |
denotes |
segments |
T8288 |
1245-1246 |
. |
denotes |
. |
T8289 |
1246-1266 |
sentence |
denotes |
is, inner segments. |
T8290 |
1247-1249 |
NN |
denotes |
is |
T8291 |
1249-1251 |
, |
denotes |
, |
T8292 |
1251-1256 |
JJ |
denotes |
inner |
T8293 |
1257-1265 |
NNS |
denotes |
segments |
T8294 |
1265-1266 |
. |
denotes |
. |
T8295 |
1266-1318 |
sentence |
denotes |
onl, outer nuclear layer with photoreceptor nuclei. |
T8296 |
1267-1270 |
NN |
denotes |
onl |
T8297 |
1270-1272 |
, |
denotes |
, |
T8298 |
1272-1277 |
JJ |
denotes |
outer |
T8299 |
1286-1291 |
NN |
denotes |
layer |
T8300 |
1278-1285 |
JJ |
denotes |
nuclear |
T8301 |
1292-1296 |
IN |
denotes |
with |
T8302 |
1297-1310 |
NN |
denotes |
photoreceptor |
T8303 |
1311-1317 |
NNS |
denotes |
nuclei |
T8304 |
1317-1318 |
. |
denotes |
. |
T8305 |
1318-1348 |
sentence |
denotes |
Scale bar = 5 μm for A and B. |
T8306 |
1319-1324 |
NN |
denotes |
Scale |
T8307 |
1325-1328 |
NN |
denotes |
bar |
T8308 |
1333-1335 |
NN |
denotes |
μm |
T8309 |
1329-1330 |
SYM |
denotes |
= |
T8310 |
1331-1332 |
CD |
denotes |
5 |
T8311 |
1336-1339 |
IN |
denotes |
for |
T8312 |
1340-1341 |
NN |
denotes |
A |
T8313 |
1342-1345 |
CC |
denotes |
and |
T8314 |
1346-1347 |
NN |
denotes |
B |
T8315 |
1347-1348 |
. |
denotes |
. |
T8372 |
1359-1371 |
NN |
denotes |
Transmission |
T8373 |
1381-1391 |
NN |
denotes |
micrograph |
T8374 |
1372-1380 |
NN |
denotes |
electron |
T8375 |
1392-1394 |
IN |
denotes |
of |
T8376 |
1395-1398 |
DT |
denotes |
the |
T8377 |
1413-1418 |
NN |
denotes |
layer |
T8378 |
1399-1404 |
JJ |
denotes |
outer |
T8379 |
1405-1412 |
NN |
denotes |
segment |
T8380 |
1419-1421 |
IN |
denotes |
of |
T8381 |
1422-1425 |
NN |
denotes |
Crx |
T8382 |
1429-1435 |
NN |
denotes |
retina |
T8383 |
1425-1426 |
SYM |
denotes |
- |
T8384 |
1426-1427 |
HYPH |
denotes |
/ |
T8385 |
1427-1428 |
SYM |
denotes |
- |
T8386 |
1436-1438 |
IN |
denotes |
at |
T8387 |
1439-1442 |
NN |
denotes |
P21 |
T8388 |
1442-1443 |
. |
denotes |
. |
T8389 |
1443-1562 |
sentence |
denotes |
Inner segments of Crx-/- photoreceptors exhibit numerous mitochondria (m indicated by arrow) as in Crx+/+ (Figure 1A). |
T8390 |
1444-1449 |
JJ |
denotes |
Inner |
T8391 |
1450-1458 |
NNS |
denotes |
segments |
T8392 |
1484-1491 |
VBP |
denotes |
exhibit |
T8393 |
1459-1461 |
IN |
denotes |
of |
T8394 |
1462-1465 |
NN |
denotes |
Crx |
T8395 |
1469-1483 |
NNS |
denotes |
photoreceptors |
T8396 |
1465-1466 |
SYM |
denotes |
- |
T8397 |
1466-1467 |
HYPH |
denotes |
/ |
T8398 |
1467-1468 |
SYM |
denotes |
- |
T8399 |
1492-1500 |
JJ |
denotes |
numerous |
T8400 |
1501-1513 |
NNS |
denotes |
mitochondria |
T8401 |
1514-1515 |
-LRB- |
denotes |
( |
T8402 |
1517-1526 |
VBN |
denotes |
indicated |
T8403 |
1515-1516 |
NN |
denotes |
m |
T8404 |
1527-1529 |
IN |
denotes |
by |
T8405 |
1530-1535 |
NN |
denotes |
arrow |
T8406 |
1535-1536 |
-RRB- |
denotes |
) |
T8407 |
1537-1539 |
IN |
denotes |
as |
T8408 |
1540-1542 |
IN |
denotes |
in |
T8409 |
1543-1546 |
NN |
denotes |
Crx |
T8410 |
1546-1547 |
SYM |
denotes |
+ |
T8411 |
1547-1548 |
HYPH |
denotes |
/ |
T8412 |
1548-1549 |
SYM |
denotes |
+ |
T8413 |
1550-1551 |
-LRB- |
denotes |
( |
T8414 |
1551-1557 |
NN |
denotes |
Figure |
T8415 |
1558-1560 |
CD |
denotes |
1A |
T8416 |
1560-1561 |
-RRB- |
denotes |
) |
T8417 |
1561-1562 |
. |
denotes |
. |
T8418 |
1562-1588 |
sentence |
denotes |
pe, pigmented epithelium. |
T8419 |
1563-1565 |
NN |
denotes |
pe |
T8420 |
1565-1567 |
, |
denotes |
, |
T8421 |
1567-1576 |
JJ |
denotes |
pigmented |
T8422 |
1577-1587 |
NN |
denotes |
epithelium |
T8423 |
1587-1588 |
. |
denotes |
. |
T8424 |
1588-1608 |
sentence |
denotes |
is, inner segments. |
T8425 |
1589-1591 |
NN |
denotes |
is |
T8426 |
1591-1593 |
, |
denotes |
, |
T8427 |
1593-1598 |
JJ |
denotes |
inner |
T8428 |
1599-1607 |
NNS |
denotes |
segments |
T8429 |
1607-1608 |
. |
denotes |
. |
T8430 |
1608-1634 |
sentence |
denotes |
onl, outer nuclear layer. |
T8431 |
1609-1612 |
NN |
denotes |
onl |
T8432 |
1612-1614 |
, |
denotes |
, |
T8433 |
1614-1619 |
JJ |
denotes |
outer |
T8434 |
1628-1633 |
NN |
denotes |
layer |
T8435 |
1620-1627 |
JJ |
denotes |
nuclear |
T8436 |
1633-1634 |
. |
denotes |
. |
T8437 |
1634-1652 |
sentence |
denotes |
Scale bar = 2 μm. |
T8438 |
1635-1640 |
NN |
denotes |
Scale |
T8439 |
1641-1644 |
NN |
denotes |
bar |
T8440 |
1649-1651 |
NN |
denotes |
μm |
T8441 |
1645-1646 |
SYM |
denotes |
= |
T8442 |
1647-1648 |
CD |
denotes |
2 |
T8443 |
1651-1652 |
. |
denotes |
. |
T8570 |
2541-2553 |
NN |
denotes |
Transmission |
T8571 |
2563-2573 |
NN |
denotes |
micrograph |
T8572 |
2554-2562 |
NN |
denotes |
electron |
T8573 |
2574-2576 |
IN |
denotes |
of |
T8574 |
2577-2580 |
NN |
denotes |
Crx |
T8575 |
2584-2590 |
NN |
denotes |
retina |
T8576 |
2580-2581 |
SYM |
denotes |
- |
T8577 |
2581-2582 |
HYPH |
denotes |
/ |
T8578 |
2582-2583 |
SYM |
denotes |
- |
T8579 |
2591-2593 |
IN |
denotes |
at |
T8580 |
2594-2597 |
NN |
denotes |
P21 |
T8581 |
2598-2599 |
-LRB- |
denotes |
( |
T8582 |
2599-2600 |
NN |
denotes |
A |
T8583 |
2601-2604 |
CC |
denotes |
and |
T8584 |
2605-2606 |
NN |
denotes |
B |
T8585 |
2606-2607 |
-RRB- |
denotes |
) |
T8586 |
2607-2609 |
, |
denotes |
, |
T8587 |
2609-2612 |
CC |
denotes |
and |
T8588 |
2613-2621 |
VBG |
denotes |
scanning |
T8589 |
2631-2641 |
NN |
denotes |
micrograph |
T8590 |
2622-2630 |
NN |
denotes |
electron |
T8591 |
2642-2644 |
IN |
denotes |
of |
T8592 |
2645-2648 |
NN |
denotes |
Crx |
T8593 |
2648-2649 |
SYM |
denotes |
- |
T8594 |
2649-2650 |
HYPH |
denotes |
/ |
T8595 |
2650-2651 |
SYM |
denotes |
- |
T8596 |
2652-2654 |
IN |
denotes |
at |
T8597 |
2655-2658 |
NN |
denotes |
P10 |
T8598 |
2659-2660 |
-LRB- |
denotes |
( |
T8599 |
2660-2661 |
NN |
denotes |
C |
T8600 |
2661-2662 |
-RRB- |
denotes |
) |
T8601 |
2663-2665 |
IN |
denotes |
of |
T8602 |
2666-2671 |
JJ |
denotes |
outer |
T8603 |
2672-2679 |
NN |
denotes |
segment |
T8604 |
2680-2685 |
NN |
denotes |
layer |
T8605 |
2685-2686 |
. |
denotes |
. |
T8606 |
2686-2760 |
sentence |
denotes |
(A) Evidence of ciliogenesis in the photoreceptor layer of Crx-/- retina. |
T8607 |
2687-2688 |
-LRB- |
denotes |
( |
T8608 |
2688-2689 |
LS |
denotes |
A |
T8609 |
2691-2699 |
NN |
denotes |
Evidence |
T8610 |
2689-2690 |
-RRB- |
denotes |
) |
T8611 |
2700-2702 |
IN |
denotes |
of |
T8612 |
2703-2715 |
NN |
denotes |
ciliogenesis |
T8613 |
2716-2718 |
IN |
denotes |
in |
T8614 |
2719-2722 |
DT |
denotes |
the |
T8615 |
2737-2742 |
NN |
denotes |
layer |
T8616 |
2723-2736 |
NN |
denotes |
photoreceptor |
T8617 |
2743-2745 |
IN |
denotes |
of |
T8618 |
2746-2749 |
NN |
denotes |
Crx |
T8619 |
2753-2759 |
NN |
denotes |
retina |
T8620 |
2749-2750 |
SYM |
denotes |
- |
T8621 |
2750-2751 |
HYPH |
denotes |
/ |
T8622 |
2751-2752 |
SYM |
denotes |
- |
T8623 |
2759-2760 |
. |
denotes |
. |
T8624 |
2760-2857 |
sentence |
denotes |
Nonmotile connecting cilia were observed in cross section (arrowheads 1,2, and 3, for examples). |
T8625 |
2761-2770 |
JJ |
denotes |
Nonmotile |
T8626 |
2782-2787 |
NNS |
denotes |
cilia |
T8627 |
2771-2781 |
VBG |
denotes |
connecting |
T8628 |
2793-2801 |
VBN |
denotes |
observed |
T8629 |
2788-2792 |
VBD |
denotes |
were |
T8630 |
2802-2804 |
IN |
denotes |
in |
T8631 |
2805-2810 |
NN |
denotes |
cross |
T8632 |
2811-2818 |
NN |
denotes |
section |
T8633 |
2819-2820 |
-LRB- |
denotes |
( |
T8634 |
2831-2832 |
CD |
denotes |
1 |
T8635 |
2820-2830 |
NNS |
denotes |
arrowheads |
T8636 |
2832-2833 |
, |
denotes |
, |
T8637 |
2833-2834 |
CD |
denotes |
2 |
T8638 |
2834-2836 |
, |
denotes |
, |
T8639 |
2836-2839 |
CC |
denotes |
and |
T8640 |
2840-2841 |
CD |
denotes |
3 |
T8641 |
2841-2843 |
, |
denotes |
, |
T8642 |
2843-2846 |
IN |
denotes |
for |
T8643 |
2847-2855 |
NNS |
denotes |
examples |
T8644 |
2855-2856 |
-RRB- |
denotes |
) |
T8645 |
2856-2857 |
. |
denotes |
. |
T8646 |
2857-2975 |
sentence |
denotes |
Connecting cilium 1 (arrowhead 1) demonstrated seven microtuble doublets, while cilium 2 and cilium 3 exhibited nine. |
T8647 |
2858-2868 |
VBG |
denotes |
Connecting |
T8648 |
2869-2875 |
NN |
denotes |
cilium |
T8649 |
2892-2904 |
VBD |
denotes |
demonstrated |
T8650 |
2876-2877 |
CD |
denotes |
1 |
T8651 |
2878-2879 |
-LRB- |
denotes |
( |
T8652 |
2879-2888 |
NN |
denotes |
arrowhead |
T8653 |
2889-2890 |
CD |
denotes |
1 |
T8654 |
2890-2891 |
-RRB- |
denotes |
) |
T8655 |
2905-2910 |
CD |
denotes |
seven |
T8656 |
2922-2930 |
NNS |
denotes |
doublets |
T8657 |
2911-2921 |
JJ |
denotes |
microtuble |
T8658 |
2930-2932 |
, |
denotes |
, |
T8659 |
2932-2937 |
IN |
denotes |
while |
T8660 |
2960-2969 |
VBD |
denotes |
exhibited |
T8661 |
2938-2944 |
NN |
denotes |
cilium |
T8662 |
2945-2946 |
CD |
denotes |
2 |
T8663 |
2947-2950 |
CC |
denotes |
and |
T8664 |
2951-2957 |
NN |
denotes |
cilium |
T8665 |
2958-2959 |
CD |
denotes |
3 |
T8666 |
2970-2974 |
CD |
denotes |
nine |
T8667 |
2974-2975 |
. |
denotes |
. |
T8668 |
2975-3250 |
sentence |
denotes |
In A, a displaced cell nucleus (n) appearing pyknotic and abnormal deposition of matrix (mx) material of unknown identity were seen, along with large amounts of membranous vesicles (arrow) which filled the photoreceptor space and appeared to be released from inner segments. |
T8669 |
2976-2978 |
IN |
denotes |
In |
T8670 |
3103-3107 |
VBN |
denotes |
seen |
T8671 |
2979-2980 |
NN |
denotes |
A |
T8672 |
2980-2982 |
, |
denotes |
, |
T8673 |
2982-2983 |
DT |
denotes |
a |
T8674 |
2999-3006 |
NN |
denotes |
nucleus |
T8675 |
2984-2993 |
VBN |
denotes |
displaced |
T8676 |
2994-2998 |
NN |
denotes |
cell |
T8677 |
3007-3008 |
-LRB- |
denotes |
( |
T8678 |
3008-3009 |
NN |
denotes |
n |
T8679 |
3009-3010 |
-RRB- |
denotes |
) |
T8680 |
3011-3020 |
VBG |
denotes |
appearing |
T8681 |
3021-3029 |
JJ |
denotes |
pyknotic |
T8682 |
3030-3033 |
CC |
denotes |
and |
T8683 |
3034-3042 |
JJ |
denotes |
abnormal |
T8684 |
3043-3053 |
NN |
denotes |
deposition |
T8685 |
3054-3056 |
IN |
denotes |
of |
T8686 |
3057-3063 |
NN |
denotes |
matrix |
T8687 |
3069-3077 |
NN |
denotes |
material |
T8688 |
3064-3065 |
-LRB- |
denotes |
( |
T8689 |
3065-3067 |
NN |
denotes |
mx |
T8690 |
3067-3068 |
-RRB- |
denotes |
) |
T8691 |
3078-3080 |
IN |
denotes |
of |
T8692 |
3081-3088 |
JJ |
denotes |
unknown |
T8693 |
3089-3097 |
NN |
denotes |
identity |
T8694 |
3098-3102 |
VBD |
denotes |
were |
T8695 |
3107-3109 |
, |
denotes |
, |
T8696 |
3109-3114 |
IN |
denotes |
along |
T8697 |
3115-3119 |
IN |
denotes |
with |
T8698 |
3120-3125 |
JJ |
denotes |
large |
T8699 |
3126-3133 |
NNS |
denotes |
amounts |
T8700 |
3134-3136 |
IN |
denotes |
of |
T8701 |
3137-3147 |
JJ |
denotes |
membranous |
T8702 |
3148-3156 |
NNS |
denotes |
vesicles |
T8703 |
3157-3158 |
-LRB- |
denotes |
( |
T8704 |
3158-3163 |
NN |
denotes |
arrow |
T8705 |
3163-3164 |
-RRB- |
denotes |
) |
T8706 |
3165-3170 |
WDT |
denotes |
which |
T8707 |
3171-3177 |
VBD |
denotes |
filled |
T8708 |
3178-3181 |
DT |
denotes |
the |
T8709 |
3196-3201 |
NN |
denotes |
space |
T8710 |
3182-3195 |
NN |
denotes |
photoreceptor |
T8711 |
3202-3205 |
CC |
denotes |
and |
T8712 |
3206-3214 |
VBD |
denotes |
appeared |
T8713 |
3215-3217 |
TO |
denotes |
to |
T8714 |
3221-3229 |
VBN |
denotes |
released |
T8715 |
3218-3220 |
VB |
denotes |
be |
T8716 |
3230-3234 |
IN |
denotes |
from |
T8717 |
3235-3240 |
JJ |
denotes |
inner |
T8718 |
3241-3249 |
NNS |
denotes |
segments |
T8719 |
3249-3250 |
. |
denotes |
. |
T8720 |
3250-3270 |
sentence |
denotes |
Scale bar = 3.7 μm. |
T8721 |
3251-3256 |
NN |
denotes |
Scale |
T8722 |
3257-3260 |
NN |
denotes |
bar |
T8723 |
3267-3269 |
NN |
denotes |
μm |
T8724 |
3261-3262 |
SYM |
denotes |
= |
T8725 |
3263-3266 |
CD |
denotes |
3.7 |
T8726 |
3269-3270 |
. |
denotes |
. |
T8727 |
3270-3420 |
sentence |
denotes |
(B) Nonmotile connecting cilium in cross section, from a Crx-/- photoreceptor, demonstrating characteristic 9+0 radial array of microtubule doublets. |
T8728 |
3271-3272 |
-LRB- |
denotes |
( |
T8729 |
3272-3273 |
LS |
denotes |
B |
T8730 |
3296-3302 |
NN |
denotes |
cilium |
T8731 |
3273-3274 |
-RRB- |
denotes |
) |
T8732 |
3275-3284 |
JJ |
denotes |
Nonmotile |
T8733 |
3285-3295 |
VBG |
denotes |
connecting |
T8734 |
3303-3305 |
IN |
denotes |
in |
T8735 |
3306-3311 |
NN |
denotes |
cross |
T8736 |
3312-3319 |
NN |
denotes |
section |
T8737 |
3319-3321 |
, |
denotes |
, |
T8738 |
3321-3325 |
IN |
denotes |
from |
T8739 |
3326-3327 |
DT |
denotes |
a |
T8740 |
3335-3348 |
NN |
denotes |
photoreceptor |
T8741 |
3328-3331 |
NN |
denotes |
Crx |
T8742 |
3331-3332 |
SYM |
denotes |
- |
T8743 |
3332-3333 |
HYPH |
denotes |
/ |
T8744 |
3333-3334 |
SYM |
denotes |
- |
T8745 |
3348-3350 |
, |
denotes |
, |
T8746 |
3350-3363 |
VBG |
denotes |
demonstrating |
T8747 |
3364-3378 |
JJ |
denotes |
characteristic |
T8748 |
3390-3395 |
NN |
denotes |
array |
T8749 |
3379-3380 |
CD |
denotes |
9 |
T8750 |
3381-3382 |
CD |
denotes |
0 |
T8751 |
3380-3381 |
SYM |
denotes |
+ |
T8752 |
3383-3389 |
JJ |
denotes |
radial |
T8753 |
3396-3398 |
IN |
denotes |
of |
T8754 |
3399-3410 |
NN |
denotes |
microtubule |
T8755 |
3411-3419 |
NNS |
denotes |
doublets |
T8756 |
3419-3420 |
. |
denotes |
. |
T8757 |
3420-3439 |
sentence |
denotes |
Scale bar = 88 nm. |
T8758 |
3421-3426 |
NN |
denotes |
Scale |
T8759 |
3427-3430 |
NN |
denotes |
bar |
T8760 |
3436-3438 |
NN |
denotes |
nm |
T8761 |
3431-3432 |
SYM |
denotes |
= |
T8762 |
3433-3435 |
CD |
denotes |
88 |
T8763 |
3438-3439 |
. |
denotes |
. |
T8764 |
3439-3585 |
sentence |
denotes |
(C) Scanning electron micrograph (SEM) of membranous vesicles (arrow shows one example) shed from inner segments of Crx-/- photoreceptors at P10. |
T8765 |
3440-3441 |
-LRB- |
denotes |
( |
T8766 |
3441-3442 |
LS |
denotes |
C |
T8767 |
3462-3472 |
NN |
denotes |
micrograph |
T8768 |
3442-3443 |
-RRB- |
denotes |
) |
T8769 |
3444-3452 |
VBG |
denotes |
Scanning |
T8770 |
3453-3461 |
NN |
denotes |
electron |
T8771 |
3473-3474 |
-LRB- |
denotes |
( |
T8772 |
3474-3477 |
NN |
denotes |
SEM |
T8773 |
3477-3478 |
-RRB- |
denotes |
) |
T8774 |
3479-3481 |
IN |
denotes |
of |
T8775 |
3482-3492 |
JJ |
denotes |
membranous |
T8776 |
3493-3501 |
NNS |
denotes |
vesicles |
T8777 |
3502-3503 |
-LRB- |
denotes |
( |
T8778 |
3509-3514 |
VBZ |
denotes |
shows |
T8779 |
3503-3508 |
NN |
denotes |
arrow |
T8780 |
3515-3518 |
CD |
denotes |
one |
T8781 |
3519-3526 |
NN |
denotes |
example |
T8782 |
3526-3527 |
-RRB- |
denotes |
) |
T8783 |
3528-3532 |
VBN |
denotes |
shed |
T8784 |
3533-3537 |
IN |
denotes |
from |
T8785 |
3538-3543 |
JJ |
denotes |
inner |
T8786 |
3544-3552 |
NNS |
denotes |
segments |
T8787 |
3553-3555 |
IN |
denotes |
of |
T8788 |
3556-3559 |
NN |
denotes |
Crx |
T8789 |
3563-3577 |
NNS |
denotes |
photoreceptors |
T8790 |
3559-3560 |
SYM |
denotes |
- |
T8791 |
3560-3561 |
HYPH |
denotes |
/ |
T8792 |
3561-3562 |
SYM |
denotes |
- |
T8793 |
3578-3580 |
IN |
denotes |
at |
T8794 |
3581-3584 |
NN |
denotes |
P10 |
T8795 |
3584-3585 |
. |
denotes |
. |
T8796 |
3585-3681 |
sentence |
denotes |
Figure shows inner segments viewed from the scleral side with the pigmented epithelium removed. |
T8797 |
3586-3592 |
NN |
denotes |
Figure |
T8798 |
3593-3598 |
VBZ |
denotes |
shows |
T8799 |
3599-3604 |
JJ |
denotes |
inner |
T8800 |
3605-3613 |
NNS |
denotes |
segments |
T8801 |
3614-3620 |
VBN |
denotes |
viewed |
T8802 |
3621-3625 |
IN |
denotes |
from |
T8803 |
3626-3629 |
DT |
denotes |
the |
T8804 |
3638-3642 |
NN |
denotes |
side |
T8805 |
3630-3637 |
JJ |
denotes |
scleral |
T8806 |
3643-3647 |
IN |
denotes |
with |
T8807 |
3673-3680 |
VBN |
denotes |
removed |
T8808 |
3648-3651 |
DT |
denotes |
the |
T8809 |
3662-3672 |
NN |
denotes |
epithelium |
T8810 |
3652-3661 |
VBN |
denotes |
pigmented |
T8811 |
3680-3681 |
. |
denotes |
. |
T8812 |
3681-3699 |
sentence |
denotes |
Scale bar = 1 μm. |
T8813 |
3682-3687 |
NN |
denotes |
Scale |
T8814 |
3688-3691 |
NN |
denotes |
bar |
T8815 |
3696-3698 |
NN |
denotes |
μm |
T8816 |
3692-3693 |
SYM |
denotes |
= |
T8817 |
3694-3695 |
CD |
denotes |
1 |
T8818 |
3698-3699 |
. |
denotes |
. |
T8923 |
6354-6359 |
NN |
denotes |
Outer |
T8924 |
6360-6367 |
NN |
denotes |
segment |
T8925 |
6368-6381 |
NN |
denotes |
morphogenesis |
T8926 |
6382-6384 |
IN |
denotes |
in |
T8927 |
6385-6388 |
NN |
denotes |
Crx |
T8928 |
6392-6406 |
NNS |
denotes |
photoreceptors |
T8929 |
6388-6389 |
SYM |
denotes |
- |
T8930 |
6389-6390 |
HYPH |
denotes |
/ |
T8931 |
6390-6391 |
SYM |
denotes |
- |
T8932 |
6406-6407 |
. |
denotes |
. |
T8933 |
6407-6611 |
sentence |
denotes |
Scanning electron microscopy of developing photoreceptors viewed from the scleral side with the pigmented epithelium removed at P7, P14, and P21 for Crx+/+ (A, C, and E) and Crx-/- (B, D, F) littermates. |
T8934 |
6408-6416 |
VBG |
denotes |
Scanning |
T8935 |
6426-6436 |
NN |
denotes |
microscopy |
T8936 |
6417-6425 |
NN |
denotes |
electron |
T8937 |
6437-6439 |
IN |
denotes |
of |
T8938 |
6440-6450 |
VBG |
denotes |
developing |
T8939 |
6451-6465 |
NNS |
denotes |
photoreceptors |
T8940 |
6466-6472 |
VBN |
denotes |
viewed |
T8941 |
6473-6477 |
IN |
denotes |
from |
T8942 |
6478-6481 |
DT |
denotes |
the |
T8943 |
6490-6494 |
NN |
denotes |
side |
T8944 |
6482-6489 |
JJ |
denotes |
scleral |
T8945 |
6495-6499 |
IN |
denotes |
with |
T8946 |
6525-6532 |
VBN |
denotes |
removed |
T8947 |
6500-6503 |
DT |
denotes |
the |
T8948 |
6514-6524 |
NN |
denotes |
epithelium |
T8949 |
6504-6513 |
JJ |
denotes |
pigmented |
T8950 |
6533-6535 |
IN |
denotes |
at |
T8951 |
6536-6538 |
NN |
denotes |
P7 |
T8952 |
6538-6540 |
, |
denotes |
, |
T8953 |
6540-6543 |
NN |
denotes |
P14 |
T8954 |
6543-6545 |
, |
denotes |
, |
T8955 |
6545-6548 |
CC |
denotes |
and |
T8956 |
6549-6552 |
NN |
denotes |
P21 |
T8957 |
6553-6556 |
IN |
denotes |
for |
T8958 |
6557-6560 |
NN |
denotes |
Crx |
T8959 |
6599-6610 |
NNS |
denotes |
littermates |
T8960 |
6560-6561 |
SYM |
denotes |
+ |
T8961 |
6561-6562 |
HYPH |
denotes |
/ |
T8962 |
6562-6563 |
SYM |
denotes |
+ |
T8963 |
6564-6565 |
-LRB- |
denotes |
( |
T8964 |
6565-6566 |
NN |
denotes |
A |
T8965 |
6566-6568 |
, |
denotes |
, |
T8966 |
6568-6569 |
NN |
denotes |
C |
T8967 |
6569-6571 |
, |
denotes |
, |
T8968 |
6571-6574 |
CC |
denotes |
and |
T8969 |
6575-6576 |
NN |
denotes |
E |
T8970 |
6576-6577 |
-RRB- |
denotes |
) |
T8971 |
6578-6581 |
CC |
denotes |
and |
T8972 |
6582-6585 |
NN |
denotes |
Crx |
T8973 |
6585-6586 |
SYM |
denotes |
- |
T8974 |
6586-6587 |
HYPH |
denotes |
/ |
T8975 |
6587-6588 |
SYM |
denotes |
- |
T8976 |
6589-6590 |
-LRB- |
denotes |
( |
T8977 |
6596-6597 |
NN |
denotes |
F |
T8978 |
6590-6591 |
NN |
denotes |
B |
T8979 |
6591-6593 |
, |
denotes |
, |
T8980 |
6593-6594 |
NN |
denotes |
D |
T8981 |
6594-6596 |
, |
denotes |
, |
T8982 |
6597-6598 |
-RRB- |
denotes |
) |
T8983 |
6610-6611 |
. |
denotes |
. |
T8984 |
6611-6715 |
sentence |
denotes |
In Crx+/+ retina, numerous connecting cilia (A, cc) were evident at P7 with rudimentary outer segments. |
T8985 |
6612-6614 |
IN |
denotes |
In |
T8986 |
6664-6668 |
VBD |
denotes |
were |
T8987 |
6615-6618 |
NN |
denotes |
Crx |
T8988 |
6622-6628 |
NN |
denotes |
retina |
T8989 |
6618-6619 |
SYM |
denotes |
+ |
T8990 |
6619-6620 |
HYPH |
denotes |
/ |
T8991 |
6620-6621 |
SYM |
denotes |
+ |
T8992 |
6628-6630 |
, |
denotes |
, |
T8993 |
6630-6638 |
JJ |
denotes |
numerous |
T8994 |
6650-6655 |
NNS |
denotes |
cilia |
T8995 |
6639-6649 |
VBG |
denotes |
connecting |
T8996 |
6656-6657 |
-LRB- |
denotes |
( |
T8997 |
6660-6662 |
NN |
denotes |
cc |
T8998 |
6657-6658 |
NN |
denotes |
A |
T8999 |
6658-6660 |
, |
denotes |
, |
T9000 |
6662-6663 |
-RRB- |
denotes |
) |
T9001 |
6669-6676 |
JJ |
denotes |
evident |
T9002 |
6677-6679 |
IN |
denotes |
at |
T9003 |
6680-6682 |
NN |
denotes |
P7 |
T9004 |
6683-6687 |
IN |
denotes |
with |
T9005 |
6688-6699 |
JJ |
denotes |
rudimentary |
T9006 |
6706-6714 |
NNS |
denotes |
segments |
T9007 |
6700-6705 |
JJ |
denotes |
outer |
T9008 |
6714-6715 |
. |
denotes |
. |
T9009 |
6715-6768 |
sentence |
denotes |
After P7, in Crx+/+ outer segment elongation occurs. |
T9010 |
6716-6721 |
IN |
denotes |
After |
T9011 |
6761-6767 |
VBZ |
denotes |
occurs |
T9012 |
6722-6724 |
NN |
denotes |
P7 |
T9013 |
6724-6726 |
, |
denotes |
, |
T9014 |
6726-6728 |
IN |
denotes |
in |
T9015 |
6729-6732 |
NN |
denotes |
Crx |
T9016 |
6732-6733 |
SYM |
denotes |
+ |
T9017 |
6733-6734 |
HYPH |
denotes |
/ |
T9018 |
6734-6735 |
SYM |
denotes |
+ |
T9019 |
6736-6741 |
JJ |
denotes |
outer |
T9020 |
6742-6749 |
NN |
denotes |
segment |
T9021 |
6750-6760 |
NN |
denotes |
elongation |
T9022 |
6767-6768 |
. |
denotes |
. |
T9023 |
6768-6860 |
sentence |
denotes |
Initially, outer segments have a paddle-like structure (C, os) which is later shed (E, os). |
T9024 |
6769-6778 |
RB |
denotes |
Initially |
T9025 |
6795-6799 |
VBP |
denotes |
have |
T9026 |
6778-6780 |
, |
denotes |
, |
T9027 |
6780-6785 |
JJ |
denotes |
outer |
T9028 |
6786-6794 |
NNS |
denotes |
segments |
T9029 |
6800-6801 |
DT |
denotes |
a |
T9030 |
6814-6823 |
NN |
denotes |
structure |
T9031 |
6802-6808 |
NN |
denotes |
paddle |
T9032 |
6809-6813 |
JJ |
denotes |
like |
T9033 |
6808-6809 |
HYPH |
denotes |
- |
T9034 |
6824-6825 |
-LRB- |
denotes |
( |
T9035 |
6828-6830 |
NN |
denotes |
os |
T9036 |
6825-6826 |
NN |
denotes |
C |
T9037 |
6826-6828 |
, |
denotes |
, |
T9038 |
6830-6831 |
-RRB- |
denotes |
) |
T9039 |
6832-6837 |
WDT |
denotes |
which |
T9040 |
6847-6851 |
VBN |
denotes |
shed |
T9041 |
6838-6840 |
VBZ |
denotes |
is |
T9042 |
6841-6846 |
RB |
denotes |
later |
T9043 |
6852-6853 |
-LRB- |
denotes |
( |
T9044 |
6856-6858 |
NN |
denotes |
os |
T9045 |
6853-6854 |
NN |
denotes |
E |
T9046 |
6854-6856 |
, |
denotes |
, |
T9047 |
6858-6859 |
-RRB- |
denotes |
) |
T9048 |
6859-6860 |
. |
denotes |
. |
T9049 |
6860-6936 |
sentence |
denotes |
In Crx-/- photoreceptors, few connecting cilia were observed at P7 (B, cc). |
T9050 |
6861-6863 |
IN |
denotes |
In |
T9051 |
6913-6921 |
VBN |
denotes |
observed |
T9052 |
6864-6867 |
NN |
denotes |
Crx |
T9053 |
6871-6885 |
NNS |
denotes |
photoreceptors |
T9054 |
6867-6868 |
SYM |
denotes |
- |
T9055 |
6868-6869 |
HYPH |
denotes |
/ |
T9056 |
6869-6870 |
SYM |
denotes |
- |
T9057 |
6885-6887 |
, |
denotes |
, |
T9058 |
6887-6890 |
JJ |
denotes |
few |
T9059 |
6902-6907 |
NNS |
denotes |
cilia |
T9060 |
6891-6901 |
VBG |
denotes |
connecting |
T9061 |
6908-6912 |
VBD |
denotes |
were |
T9062 |
6922-6924 |
IN |
denotes |
at |
T9063 |
6925-6927 |
NN |
denotes |
P7 |
T9064 |
6928-6929 |
-LRB- |
denotes |
( |
T9065 |
6932-6934 |
NN |
denotes |
cc |
T9066 |
6929-6930 |
NN |
denotes |
B |
T9067 |
6930-6932 |
, |
denotes |
, |
T9068 |
6934-6935 |
-RRB- |
denotes |
) |
T9069 |
6935-6936 |
. |
denotes |
. |
T9070 |
6936-7086 |
sentence |
denotes |
After P7, connecting cilia were more numerous and occasionally a malformed outer segment was noted extending from a connecting cilium (D and F, cc*). |
T9071 |
6937-6942 |
IN |
denotes |
After |
T9072 |
6964-6968 |
VBD |
denotes |
were |
T9073 |
6943-6945 |
NN |
denotes |
P7 |
T9074 |
6945-6947 |
, |
denotes |
, |
T9075 |
6947-6957 |
VBG |
denotes |
connecting |
T9076 |
6958-6963 |
NNS |
denotes |
cilia |
T9077 |
6969-6973 |
RBR |
denotes |
more |
T9078 |
6974-6982 |
JJ |
denotes |
numerous |
T9079 |
6983-6986 |
CC |
denotes |
and |
T9080 |
6987-6999 |
RB |
denotes |
occasionally |
T9081 |
7030-7035 |
VBN |
denotes |
noted |
T9082 |
7000-7001 |
DT |
denotes |
a |
T9083 |
7018-7025 |
NN |
denotes |
segment |
T9084 |
7002-7011 |
JJ |
denotes |
malformed |
T9085 |
7012-7017 |
JJ |
denotes |
outer |
T9086 |
7026-7029 |
VBD |
denotes |
was |
T9087 |
7036-7045 |
VBG |
denotes |
extending |
T9088 |
7046-7050 |
IN |
denotes |
from |
T9089 |
7051-7052 |
DT |
denotes |
a |
T9090 |
7064-7070 |
NN |
denotes |
cilium |
T9091 |
7053-7063 |
VBG |
denotes |
connecting |
T9092 |
7071-7072 |
-LRB- |
denotes |
( |
T9093 |
7081-7084 |
NN |
denotes |
cc* |
T9094 |
7072-7073 |
NN |
denotes |
D |
T9095 |
7074-7077 |
CC |
denotes |
and |
T9096 |
7078-7079 |
NN |
denotes |
F |
T9097 |
7079-7081 |
, |
denotes |
, |
T9098 |
7084-7085 |
-RRB- |
denotes |
) |
T9099 |
7085-7086 |
. |
denotes |
. |
T9100 |
7086-7149 |
sentence |
denotes |
These were rarely observed in Crx+/+ and only at P14 (C, cc*). |
T9101 |
7087-7092 |
DT |
denotes |
These |
T9102 |
7105-7113 |
VBN |
denotes |
observed |
T9103 |
7093-7097 |
VBD |
denotes |
were |
T9104 |
7098-7104 |
RB |
denotes |
rarely |
T9105 |
7114-7116 |
IN |
denotes |
in |
T9106 |
7117-7120 |
NN |
denotes |
Crx |
T9107 |
7120-7121 |
SYM |
denotes |
+ |
T9108 |
7121-7122 |
HYPH |
denotes |
/ |
T9109 |
7122-7123 |
SYM |
denotes |
+ |
T9110 |
7124-7127 |
CC |
denotes |
and |
T9111 |
7128-7132 |
RB |
denotes |
only |
T9112 |
7133-7135 |
IN |
denotes |
at |
T9113 |
7136-7139 |
NN |
denotes |
P14 |
T9114 |
7140-7141 |
-LRB- |
denotes |
( |
T9115 |
7144-7147 |
NN |
denotes |
cc* |
T9116 |
7141-7142 |
NN |
denotes |
C |
T9117 |
7142-7144 |
, |
denotes |
, |
T9118 |
7147-7148 |
-RRB- |
denotes |
) |
T9119 |
7148-7149 |
. |
denotes |
. |
T9120 |
7149-7219 |
sentence |
denotes |
At P21, abnormally long connecting cilia are noted in Crx-/- (F, cc). |
T9121 |
7150-7152 |
IN |
denotes |
At |
T9122 |
7195-7200 |
VBN |
denotes |
noted |
T9123 |
7153-7156 |
NN |
denotes |
P21 |
T9124 |
7156-7158 |
, |
denotes |
, |
T9125 |
7158-7168 |
RB |
denotes |
abnormally |
T9126 |
7169-7173 |
JJ |
denotes |
long |
T9127 |
7185-7190 |
NNS |
denotes |
cilia |
T9128 |
7174-7184 |
VBG |
denotes |
connecting |
T9129 |
7191-7194 |
VBP |
denotes |
are |
T9130 |
7201-7203 |
IN |
denotes |
in |
T9131 |
7204-7207 |
NN |
denotes |
Crx |
T9132 |
7207-7208 |
SYM |
denotes |
- |
T9133 |
7208-7209 |
HYPH |
denotes |
/ |
T9134 |
7209-7210 |
SYM |
denotes |
- |
T9135 |
7211-7212 |
-LRB- |
denotes |
( |
T9136 |
7215-7217 |
NN |
denotes |
cc |
T9137 |
7212-7213 |
NN |
denotes |
F |
T9138 |
7213-7215 |
, |
denotes |
, |
T9139 |
7217-7218 |
-RRB- |
denotes |
) |
T9140 |
7218-7219 |
. |
denotes |
. |
T9141 |
7219-7238 |
sentence |
denotes |
Scale bars = 10 μm |
T9142 |
7220-7225 |
NN |
denotes |
Scale |
T9143 |
7226-7230 |
NNS |
denotes |
bars |
T9144 |
7236-7238 |
NN |
denotes |
μm |
T9145 |
7231-7232 |
SYM |
denotes |
= |
T9146 |
7233-7235 |
CD |
denotes |
10 |
T9204 |
7249-7261 |
NN |
denotes |
Transmission |
T9205 |
7271-7282 |
NNS |
denotes |
micrographs |
T9206 |
7262-7270 |
NN |
denotes |
electron |
T9207 |
7283-7285 |
IN |
denotes |
of |
T9208 |
7286-7289 |
NN |
denotes |
Crx |
T9209 |
7293-7307 |
NNS |
denotes |
photoreceptors |
T9210 |
7289-7290 |
SYM |
denotes |
- |
T9211 |
7290-7291 |
HYPH |
denotes |
/ |
T9212 |
7291-7292 |
SYM |
denotes |
- |
T9213 |
7308-7310 |
IN |
denotes |
in |
T9214 |
7311-7314 |
DT |
denotes |
the |
T9215 |
7329-7334 |
NN |
denotes |
layer |
T9216 |
7315-7328 |
NN |
denotes |
photoreceptor |
T9217 |
7335-7337 |
IN |
denotes |
at |
T9218 |
7338-7340 |
NN |
denotes |
P7 |
T9219 |
7340-7341 |
. |
denotes |
. |
T9220 |
7341-7488 |
sentence |
denotes |
(A) Photoreceptor layer of Crx+/+ retina demonstrating nascent outer segment structures (arrow) emerging from photoreceptor connecting cilia (cc). |
T9221 |
7342-7343 |
-LRB- |
denotes |
( |
T9222 |
7343-7344 |
LS |
denotes |
A |
T9223 |
7360-7365 |
NN |
denotes |
layer |
T9224 |
7344-7345 |
-RRB- |
denotes |
) |
T9225 |
7346-7359 |
NN |
denotes |
Photoreceptor |
T9226 |
7366-7368 |
IN |
denotes |
of |
T9227 |
7369-7372 |
NN |
denotes |
Crx |
T9228 |
7376-7382 |
NN |
denotes |
retina |
T9229 |
7372-7373 |
SYM |
denotes |
+ |
T9230 |
7373-7374 |
HYPH |
denotes |
/ |
T9231 |
7374-7375 |
SYM |
denotes |
+ |
T9232 |
7383-7396 |
VBG |
denotes |
demonstrating |
T9233 |
7397-7404 |
JJ |
denotes |
nascent |
T9234 |
7419-7429 |
NNS |
denotes |
structures |
T9235 |
7405-7410 |
JJ |
denotes |
outer |
T9236 |
7411-7418 |
NN |
denotes |
segment |
T9237 |
7438-7446 |
VBG |
denotes |
emerging |
T9238 |
7430-7431 |
-LRB- |
denotes |
( |
T9239 |
7431-7436 |
NN |
denotes |
arrow |
T9240 |
7436-7437 |
-RRB- |
denotes |
) |
T9241 |
7447-7451 |
IN |
denotes |
from |
T9242 |
7452-7465 |
NN |
denotes |
photoreceptor |
T9243 |
7477-7482 |
NNS |
denotes |
cilia |
T9244 |
7466-7476 |
VBG |
denotes |
connecting |
T9245 |
7483-7484 |
-LRB- |
denotes |
( |
T9246 |
7484-7486 |
NN |
denotes |
cc |
T9247 |
7486-7487 |
-RRB- |
denotes |
) |
T9248 |
7487-7488 |
. |
denotes |
. |
T9249 |
7488-7628 |
sentence |
denotes |
(B) Crx-/- photoreceptors exhibited connecting cilia (cc) at this early stage, however, nascent outer segment structures were not observed. |
T9250 |
7489-7490 |
-LRB- |
denotes |
( |
T9251 |
7490-7491 |
LS |
denotes |
B |
T9252 |
7619-7627 |
VBN |
denotes |
observed |
T9253 |
7491-7492 |
-RRB- |
denotes |
) |
T9254 |
7493-7496 |
NN |
denotes |
Crx |
T9255 |
7500-7514 |
NNS |
denotes |
photoreceptors |
T9256 |
7496-7497 |
SYM |
denotes |
- |
T9257 |
7497-7498 |
HYPH |
denotes |
/ |
T9258 |
7498-7499 |
SYM |
denotes |
- |
T9259 |
7515-7524 |
VBD |
denotes |
exhibited |
T9260 |
7525-7535 |
VBG |
denotes |
connecting |
T9261 |
7536-7541 |
NNS |
denotes |
cilia |
T9262 |
7542-7543 |
-LRB- |
denotes |
( |
T9263 |
7543-7545 |
NN |
denotes |
cc |
T9264 |
7545-7546 |
-RRB- |
denotes |
) |
T9265 |
7547-7549 |
IN |
denotes |
at |
T9266 |
7550-7554 |
DT |
denotes |
this |
T9267 |
7561-7566 |
NN |
denotes |
stage |
T9268 |
7555-7560 |
JJ |
denotes |
early |
T9269 |
7566-7568 |
, |
denotes |
, |
T9270 |
7568-7575 |
RB |
denotes |
however |
T9271 |
7575-7577 |
, |
denotes |
, |
T9272 |
7577-7584 |
JJ |
denotes |
nascent |
T9273 |
7599-7609 |
NNS |
denotes |
structures |
T9274 |
7585-7590 |
JJ |
denotes |
outer |
T9275 |
7591-7598 |
NN |
denotes |
segment |
T9276 |
7610-7614 |
VBD |
denotes |
were |
T9277 |
7615-7618 |
RB |
denotes |
not |
T9278 |
7627-7628 |
. |
denotes |
. |
T9279 |
7628-7646 |
sentence |
denotes |
Scale Bar = 1 μm. |
T9280 |
7629-7634 |
NN |
denotes |
Scale |
T9281 |
7635-7638 |
NN |
denotes |
Bar |
T9282 |
7643-7645 |
NN |
denotes |
μm |
T9283 |
7639-7640 |
SYM |
denotes |
= |
T9284 |
7641-7642 |
CD |
denotes |
1 |
T9285 |
7645-7646 |
. |
denotes |
. |
T9319 |
8237-8245 |
VBG |
denotes |
Scanning |
T9320 |
8255-8265 |
NN |
denotes |
microscopy |
T9321 |
8246-8254 |
NN |
denotes |
electron |
T9322 |
8266-8268 |
IN |
denotes |
of |
T9323 |
8269-8279 |
NN |
denotes |
peripherin |
T9324 |
8308-8322 |
NNS |
denotes |
photoreceptors |
T9325 |
8279-8280 |
SYM |
denotes |
- |
T9326 |
8280-8281 |
HYPH |
denotes |
/ |
T9327 |
8281-8282 |
SYM |
denotes |
- |
T9328 |
8283-8284 |
-LRB- |
denotes |
( |
T9329 |
8284-8285 |
NN |
denotes |
A |
T9330 |
8285-8286 |
-RRB- |
denotes |
) |
T9331 |
8287-8290 |
CC |
denotes |
and |
T9332 |
8291-8300 |
NN |
denotes |
rhodopsin |
T9333 |
8300-8301 |
SYM |
denotes |
- |
T9334 |
8301-8302 |
HYPH |
denotes |
/ |
T9335 |
8302-8303 |
SYM |
denotes |
- |
T9336 |
8304-8305 |
-LRB- |
denotes |
( |
T9337 |
8305-8306 |
NN |
denotes |
B |
T9338 |
8306-8307 |
-RRB- |
denotes |
) |
T9339 |
8323-8325 |
IN |
denotes |
at |
T9340 |
8326-8329 |
NN |
denotes |
P21 |
T9341 |
8329-8331 |
, |
denotes |
, |
T9342 |
8331-8337 |
VBN |
denotes |
viewed |
T9343 |
8338-8342 |
IN |
denotes |
from |
T9344 |
8343-8346 |
DT |
denotes |
the |
T9345 |
8355-8359 |
NN |
denotes |
side |
T9346 |
8347-8354 |
JJ |
denotes |
scleral |
T9347 |
8360-8364 |
IN |
denotes |
with |
T9348 |
8390-8397 |
VBN |
denotes |
removed |
T9349 |
8365-8368 |
DT |
denotes |
the |
T9350 |
8379-8389 |
NN |
denotes |
epithelium |
T9351 |
8369-8378 |
JJ |
denotes |
pigmented |
T9352 |
8397-8398 |
. |
denotes |
. |
T9353 |
8398-8421 |
sentence |
denotes |
cc, connecting cilium. |
T9354 |
8399-8401 |
NN |
denotes |
cc |
T9355 |
8401-8403 |
, |
denotes |
, |
T9356 |
8403-8413 |
VBG |
denotes |
connecting |
T9357 |
8414-8420 |
NN |
denotes |
cilium |
T9358 |
8420-8421 |
. |
denotes |
. |
T9359 |
8421-8440 |
sentence |
denotes |
is, inner segment. |
T9360 |
8422-8424 |
NN |
denotes |
is |
T9361 |
8424-8426 |
, |
denotes |
, |
T9362 |
8426-8431 |
JJ |
denotes |
inner |
T9363 |
8432-8439 |
NN |
denotes |
segment |
T9364 |
8439-8440 |
. |
denotes |
. |
T9365 |
8440-8459 |
sentence |
denotes |
Scale bar = 10 μm. |
T9366 |
8441-8446 |
NN |
denotes |
Scale |
T9367 |
8447-8450 |
NN |
denotes |
bar |
T9368 |
8456-8458 |
NN |
denotes |
μm |
T9369 |
8451-8452 |
SYM |
denotes |
= |
T9370 |
8453-8455 |
CD |
denotes |
10 |
T9371 |
8458-8459 |
. |
denotes |
. |
T9460 |
10102-10114 |
NN |
denotes |
Transmission |
T9461 |
10124-10135 |
NNS |
denotes |
micrographs |
T9462 |
10115-10123 |
NN |
denotes |
electron |
T9463 |
10136-10138 |
IN |
denotes |
of |
T9464 |
10139-10142 |
DT |
denotes |
the |
T9465 |
10159-10164 |
NN |
denotes |
layer |
T9466 |
10143-10148 |
JJ |
denotes |
outer |
T9467 |
10149-10158 |
NN |
denotes |
plexiform |
T9468 |
10165-10167 |
IN |
denotes |
in |
T9469 |
10168-10171 |
NN |
denotes |
Crx |
T9470 |
10175-10182 |
NNS |
denotes |
retinas |
T9471 |
10171-10172 |
SYM |
denotes |
- |
T9472 |
10172-10173 |
HYPH |
denotes |
/ |
T9473 |
10173-10174 |
SYM |
denotes |
- |
T9474 |
10182-10183 |
. |
denotes |
. |
T9475 |
10183-10287 |
sentence |
denotes |
(A) In Crx+/+ retina at P21, newly formed rod spherules were abundant (arrow demonstrates one example). |
T9476 |
10184-10185 |
-LRB- |
denotes |
( |
T9477 |
10185-10186 |
LS |
denotes |
A |
T9478 |
10240-10244 |
VBD |
denotes |
were |
T9479 |
10186-10187 |
-RRB- |
denotes |
) |
T9480 |
10188-10190 |
IN |
denotes |
In |
T9481 |
10191-10194 |
NN |
denotes |
Crx |
T9482 |
10198-10204 |
NN |
denotes |
retina |
T9483 |
10194-10195 |
SYM |
denotes |
+ |
T9484 |
10195-10196 |
HYPH |
denotes |
/ |
T9485 |
10196-10197 |
SYM |
denotes |
+ |
T9486 |
10205-10207 |
IN |
denotes |
at |
T9487 |
10208-10211 |
NN |
denotes |
P21 |
T9488 |
10211-10213 |
, |
denotes |
, |
T9489 |
10213-10218 |
RB |
denotes |
newly |
T9490 |
10219-10225 |
VBN |
denotes |
formed |
T9491 |
10230-10239 |
NNS |
denotes |
spherules |
T9492 |
10226-10229 |
NN |
denotes |
rod |
T9493 |
10245-10253 |
JJ |
denotes |
abundant |
T9494 |
10254-10255 |
-LRB- |
denotes |
( |
T9495 |
10261-10273 |
VBZ |
denotes |
demonstrates |
T9496 |
10255-10260 |
NN |
denotes |
arrow |
T9497 |
10274-10277 |
CD |
denotes |
one |
T9498 |
10278-10285 |
NN |
denotes |
example |
T9499 |
10285-10286 |
-RRB- |
denotes |
) |
T9500 |
10286-10287 |
. |
denotes |
. |
T9501 |
10287-10387 |
sentence |
denotes |
The spherules were club-shaped and contained a single invaginating synapse with one ribbon complex. |
T9502 |
10288-10291 |
DT |
denotes |
The |
T9503 |
10292-10301 |
NNS |
denotes |
spherules |
T9504 |
10302-10306 |
VBD |
denotes |
were |
T9505 |
10307-10311 |
NN |
denotes |
club |
T9506 |
10312-10318 |
VBN |
denotes |
shaped |
T9507 |
10311-10312 |
HYPH |
denotes |
- |
T9508 |
10319-10322 |
CC |
denotes |
and |
T9509 |
10323-10332 |
VBD |
denotes |
contained |
T9510 |
10333-10334 |
DT |
denotes |
a |
T9511 |
10355-10362 |
NN |
denotes |
synapse |
T9512 |
10335-10341 |
JJ |
denotes |
single |
T9513 |
10342-10354 |
VBG |
denotes |
invaginating |
T9514 |
10363-10367 |
IN |
denotes |
with |
T9515 |
10368-10371 |
CD |
denotes |
one |
T9516 |
10379-10386 |
NN |
denotes |
complex |
T9517 |
10372-10378 |
NN |
denotes |
ribbon |
T9518 |
10386-10387 |
. |
denotes |
. |
T9519 |
10387-10501 |
sentence |
denotes |
Cone terminals form large, flat pedicles that contain many invaginating synapses with separate ribbon structures. |
T9520 |
10388-10392 |
NN |
denotes |
Cone |
T9521 |
10393-10402 |
NNS |
denotes |
terminals |
T9522 |
10403-10407 |
VBP |
denotes |
form |
T9523 |
10408-10413 |
JJ |
denotes |
large |
T9524 |
10420-10428 |
NNS |
denotes |
pedicles |
T9525 |
10413-10415 |
, |
denotes |
, |
T9526 |
10415-10419 |
JJ |
denotes |
flat |
T9527 |
10429-10433 |
WDT |
denotes |
that |
T9528 |
10434-10441 |
VBP |
denotes |
contain |
T9529 |
10442-10446 |
JJ |
denotes |
many |
T9530 |
10460-10468 |
NNS |
denotes |
synapses |
T9531 |
10447-10459 |
VBG |
denotes |
invaginating |
T9532 |
10469-10473 |
IN |
denotes |
with |
T9533 |
10474-10482 |
JJ |
denotes |
separate |
T9534 |
10490-10500 |
NNS |
denotes |
structures |
T9535 |
10483-10489 |
NN |
denotes |
ribbon |
T9536 |
10500-10501 |
. |
denotes |
. |
T9537 |
10501-10595 |
sentence |
denotes |
These terminals were more scarce, but apparent in Crx+/+ retinas at P21 (one example in box). |
T9538 |
10502-10507 |
DT |
denotes |
These |
T9539 |
10508-10517 |
NNS |
denotes |
terminals |
T9540 |
10518-10522 |
VBD |
denotes |
were |
T9541 |
10523-10527 |
RBR |
denotes |
more |
T9542 |
10528-10534 |
JJ |
denotes |
scarce |
T9543 |
10534-10536 |
, |
denotes |
, |
T9544 |
10536-10539 |
CC |
denotes |
but |
T9545 |
10540-10548 |
JJ |
denotes |
apparent |
T9546 |
10549-10551 |
IN |
denotes |
in |
T9547 |
10552-10555 |
NN |
denotes |
Crx |
T9548 |
10559-10566 |
NNS |
denotes |
retinas |
T9549 |
10555-10556 |
SYM |
denotes |
+ |
T9550 |
10556-10557 |
HYPH |
denotes |
/ |
T9551 |
10557-10558 |
SYM |
denotes |
+ |
T9552 |
10567-10569 |
IN |
denotes |
at |
T9553 |
10570-10573 |
NN |
denotes |
P21 |
T9554 |
10574-10575 |
-LRB- |
denotes |
( |
T9555 |
10579-10586 |
NN |
denotes |
example |
T9556 |
10575-10578 |
CD |
denotes |
one |
T9557 |
10587-10589 |
IN |
denotes |
in |
T9558 |
10590-10593 |
NN |
denotes |
box |
T9559 |
10593-10594 |
-RRB- |
denotes |
) |
T9560 |
10594-10595 |
. |
denotes |
. |
T9561 |
10595-10723 |
sentence |
denotes |
(B) In the outer plexiform layer (OPL) of Crx-/- retinas, photoreceptor terminals appeared highly disorganized at P21 (arrows). |
T9562 |
10596-10597 |
-LRB- |
denotes |
( |
T9563 |
10597-10598 |
LS |
denotes |
B |
T9564 |
10678-10686 |
VBD |
denotes |
appeared |
T9565 |
10598-10599 |
-RRB- |
denotes |
) |
T9566 |
10600-10602 |
IN |
denotes |
In |
T9567 |
10603-10606 |
DT |
denotes |
the |
T9568 |
10623-10628 |
NN |
denotes |
layer |
T9569 |
10607-10612 |
JJ |
denotes |
outer |
T9570 |
10613-10622 |
NN |
denotes |
plexiform |
T9571 |
10629-10630 |
-LRB- |
denotes |
( |
T9572 |
10630-10633 |
NN |
denotes |
OPL |
T9573 |
10633-10634 |
-RRB- |
denotes |
) |
T9574 |
10635-10637 |
IN |
denotes |
of |
T9575 |
10638-10641 |
NN |
denotes |
Crx |
T9576 |
10645-10652 |
NNS |
denotes |
retinas |
T9577 |
10641-10642 |
SYM |
denotes |
- |
T9578 |
10642-10643 |
HYPH |
denotes |
/ |
T9579 |
10643-10644 |
SYM |
denotes |
- |
T9580 |
10652-10654 |
, |
denotes |
, |
T9581 |
10654-10667 |
NN |
denotes |
photoreceptor |
T9582 |
10668-10677 |
NNS |
denotes |
terminals |
T9583 |
10687-10693 |
RB |
denotes |
highly |
T9584 |
10694-10706 |
JJ |
denotes |
disorganized |
T9585 |
10707-10709 |
IN |
denotes |
at |
T9586 |
10710-10713 |
NN |
denotes |
P21 |
T9587 |
10714-10715 |
-LRB- |
denotes |
( |
T9588 |
10715-10721 |
NNS |
denotes |
arrows |
T9589 |
10721-10722 |
-RRB- |
denotes |
) |
T9590 |
10722-10723 |
. |
denotes |
. |
T9591 |
10723-10776 |
sentence |
denotes |
Well-formed pedicles and spherules were not evident. |
T9592 |
10724-10728 |
RB |
denotes |
Well |
T9593 |
10729-10735 |
VBN |
denotes |
formed |
T9594 |
10728-10729 |
HYPH |
denotes |
- |
T9595 |
10736-10744 |
NNS |
denotes |
pedicles |
T9596 |
10759-10763 |
VBD |
denotes |
were |
T9597 |
10745-10748 |
CC |
denotes |
and |
T9598 |
10749-10758 |
NNS |
denotes |
spherules |
T9599 |
10764-10767 |
RB |
denotes |
not |
T9600 |
10768-10775 |
JJ |
denotes |
evident |
T9601 |
10775-10776 |
. |
denotes |
. |
T9602 |
10776-10906 |
sentence |
denotes |
Putative terminals containing ribbon-like structures were apparent, suggesting at least limited generation of synapse components. |
T9603 |
10777-10785 |
JJ |
denotes |
Putative |
T9604 |
10786-10795 |
NNS |
denotes |
terminals |
T9605 |
10830-10834 |
VBD |
denotes |
were |
T9606 |
10796-10806 |
VBG |
denotes |
containing |
T9607 |
10807-10813 |
NN |
denotes |
ribbon |
T9608 |
10814-10818 |
JJ |
denotes |
like |
T9609 |
10813-10814 |
HYPH |
denotes |
- |
T9610 |
10819-10829 |
NNS |
denotes |
structures |
T9611 |
10835-10843 |
JJ |
denotes |
apparent |
T9612 |
10843-10845 |
, |
denotes |
, |
T9613 |
10845-10855 |
VBG |
denotes |
suggesting |
T9614 |
10856-10858 |
RB |
denotes |
at |
T9615 |
10859-10864 |
RBS |
denotes |
least |
T9616 |
10865-10872 |
JJ |
denotes |
limited |
T9617 |
10873-10883 |
NN |
denotes |
generation |
T9618 |
10884-10886 |
IN |
denotes |
of |
T9619 |
10887-10894 |
NN |
denotes |
synapse |
T9620 |
10895-10905 |
NNS |
denotes |
components |
T9621 |
10905-10906 |
. |
denotes |
. |
T9622 |
10906-11003 |
sentence |
denotes |
Many terminals appeared to contain multiple ribbon-like structures, instead of a singule ribbon. |
T9623 |
10907-10911 |
JJ |
denotes |
Many |
T9624 |
10912-10921 |
NNS |
denotes |
terminals |
T9625 |
10922-10930 |
VBD |
denotes |
appeared |
T9626 |
10931-10933 |
TO |
denotes |
to |
T9627 |
10934-10941 |
VB |
denotes |
contain |
T9628 |
10942-10950 |
JJ |
denotes |
multiple |
T9629 |
10963-10973 |
NNS |
denotes |
structures |
T9630 |
10951-10957 |
NN |
denotes |
ribbon |
T9631 |
10958-10962 |
JJ |
denotes |
like |
T9632 |
10957-10958 |
HYPH |
denotes |
- |
T9633 |
10973-10975 |
, |
denotes |
, |
T9634 |
10975-10982 |
RB |
denotes |
instead |
T9635 |
10983-10985 |
IN |
denotes |
of |
T9636 |
10986-10987 |
DT |
denotes |
a |
T9637 |
10996-11002 |
NN |
denotes |
ribbon |
T9638 |
10988-10995 |
JJ |
denotes |
singule |
T9639 |
11002-11003 |
. |
denotes |
. |
T9640 |
11003-11110 |
sentence |
denotes |
For example, terminal 1 and 2 contained two ribbons each, whereas terminal 3 appeared to contain only one. |
T9641 |
11004-11007 |
IN |
denotes |
For |
T9642 |
11034-11043 |
VBD |
denotes |
contained |
T9643 |
11008-11015 |
NN |
denotes |
example |
T9644 |
11015-11017 |
, |
denotes |
, |
T9645 |
11017-11025 |
NN |
denotes |
terminal |
T9646 |
11026-11027 |
CD |
denotes |
1 |
T9647 |
11028-11031 |
CC |
denotes |
and |
T9648 |
11032-11033 |
CD |
denotes |
2 |
T9649 |
11044-11047 |
CD |
denotes |
two |
T9650 |
11048-11055 |
NNS |
denotes |
ribbons |
T9651 |
11056-11060 |
DT |
denotes |
each |
T9652 |
11060-11062 |
, |
denotes |
, |
T9653 |
11062-11069 |
IN |
denotes |
whereas |
T9654 |
11081-11089 |
VBD |
denotes |
appeared |
T9655 |
11070-11078 |
NN |
denotes |
terminal |
T9656 |
11079-11080 |
CD |
denotes |
3 |
T9657 |
11090-11092 |
TO |
denotes |
to |
T9658 |
11093-11100 |
VB |
denotes |
contain |
T9659 |
11101-11105 |
RB |
denotes |
only |
T9660 |
11106-11109 |
CD |
denotes |
one |
T9661 |
11109-11110 |
. |
denotes |
. |
T9662 |
11110-11138 |
sentence |
denotes |
opl, outer plexiform layer. |
T9663 |
11111-11114 |
NN |
denotes |
opl |
T9664 |
11114-11116 |
, |
denotes |
, |
T9665 |
11116-11121 |
JJ |
denotes |
outer |
T9666 |
11132-11137 |
NN |
denotes |
layer |
T9667 |
11122-11131 |
NN |
denotes |
plexiform |
T9668 |
11137-11138 |
. |
denotes |
. |
T9669 |
11138-11156 |
sentence |
denotes |
Scale bar = 2 μm. |
T9670 |
11139-11144 |
NN |
denotes |
Scale |
T9671 |
11145-11148 |
NN |
denotes |
bar |
T9672 |
11153-11155 |
NN |
denotes |
μm |
T9673 |
11149-11150 |
SYM |
denotes |
= |
T9674 |
11151-11152 |
CD |
denotes |
2 |
T9675 |
11155-11156 |
. |
denotes |
. |
T9811 |
11167-11179 |
NN |
denotes |
Transmission |
T9812 |
11189-11200 |
NNS |
denotes |
micrographs |
T9813 |
11180-11188 |
NN |
denotes |
electron |
T9814 |
11201-11203 |
IN |
denotes |
of |
T9815 |
11204-11207 |
DT |
denotes |
the |
T9816 |
11224-11229 |
NN |
denotes |
layer |
T9817 |
11208-11213 |
JJ |
denotes |
outer |
T9818 |
11214-11223 |
NN |
denotes |
plexiform |
T9819 |
11230-11232 |
IN |
denotes |
in |
T9820 |
11233-11236 |
NN |
denotes |
Crx |
T9821 |
11240-11247 |
NNS |
denotes |
retinas |
T9822 |
11236-11237 |
SYM |
denotes |
- |
T9823 |
11237-11238 |
HYPH |
denotes |
/ |
T9824 |
11238-11239 |
SYM |
denotes |
- |
T9825 |
11248-11250 |
IN |
denotes |
at |
T9826 |
11251-11254 |
NN |
denotes |
P21 |
T9827 |
11254-11255 |
. |
denotes |
. |
T9828 |
11255-11345 |
sentence |
denotes |
(A) Crx+/+ rod spherules contained a single invaginating synapse with one ribbon complex. |
T9829 |
11256-11257 |
-LRB- |
denotes |
( |
T9830 |
11257-11258 |
LS |
denotes |
A |
T9831 |
11281-11290 |
VBD |
denotes |
contained |
T9832 |
11258-11259 |
-RRB- |
denotes |
) |
T9833 |
11260-11263 |
NN |
denotes |
Crx |
T9834 |
11271-11280 |
NNS |
denotes |
spherules |
T9835 |
11263-11264 |
SYM |
denotes |
+ |
T9836 |
11264-11265 |
HYPH |
denotes |
/ |
T9837 |
11265-11266 |
SYM |
denotes |
+ |
T9838 |
11267-11270 |
NN |
denotes |
rod |
T9839 |
11291-11292 |
DT |
denotes |
a |
T9840 |
11313-11320 |
NN |
denotes |
synapse |
T9841 |
11293-11299 |
JJ |
denotes |
single |
T9842 |
11300-11312 |
VBG |
denotes |
invaginating |
T9843 |
11321-11325 |
IN |
denotes |
with |
T9844 |
11326-11329 |
CD |
denotes |
one |
T9845 |
11337-11344 |
NN |
denotes |
complex |
T9846 |
11330-11336 |
NN |
denotes |
ribbon |
T9847 |
11344-11345 |
. |
denotes |
. |
T9848 |
11345-11396 |
sentence |
denotes |
The spherule was a blunt or club-shaped structure. |
T9849 |
11346-11349 |
DT |
denotes |
The |
T9850 |
11350-11358 |
NN |
denotes |
spherule |
T9851 |
11359-11362 |
VBD |
denotes |
was |
T9852 |
11363-11364 |
DT |
denotes |
a |
T9853 |
11386-11395 |
NN |
denotes |
structure |
T9854 |
11365-11370 |
JJ |
denotes |
blunt |
T9855 |
11371-11373 |
CC |
denotes |
or |
T9856 |
11374-11378 |
NN |
denotes |
club |
T9857 |
11379-11385 |
VBN |
denotes |
shaped |
T9858 |
11378-11379 |
HYPH |
denotes |
- |
T9859 |
11395-11396 |
. |
denotes |
. |
T9860 |
11396-11462 |
sentence |
denotes |
(B) Crx+/+ rod terminals contained a single ribbon structure (r). |
T9861 |
11397-11398 |
-LRB- |
denotes |
( |
T9862 |
11398-11399 |
LS |
denotes |
B |
T9863 |
11422-11431 |
VBD |
denotes |
contained |
T9864 |
11399-11400 |
-RRB- |
denotes |
) |
T9865 |
11401-11404 |
NN |
denotes |
Crx |
T9866 |
11412-11421 |
NNS |
denotes |
terminals |
T9867 |
11404-11405 |
SYM |
denotes |
+ |
T9868 |
11405-11406 |
HYPH |
denotes |
/ |
T9869 |
11406-11407 |
SYM |
denotes |
+ |
T9870 |
11408-11411 |
NN |
denotes |
rod |
T9871 |
11432-11433 |
DT |
denotes |
a |
T9872 |
11448-11457 |
NN |
denotes |
structure |
T9873 |
11434-11440 |
JJ |
denotes |
single |
T9874 |
11441-11447 |
NN |
denotes |
ribbon |
T9875 |
11458-11459 |
-LRB- |
denotes |
( |
T9876 |
11459-11460 |
NN |
denotes |
r |
T9877 |
11460-11461 |
-RRB- |
denotes |
) |
T9878 |
11461-11462 |
. |
denotes |
. |
T9879 |
11462-11533 |
sentence |
denotes |
Two processes, from horizontal cells (h), contacted the rod laterally. |
T9880 |
11463-11466 |
CD |
denotes |
Two |
T9881 |
11467-11476 |
NNS |
denotes |
processes |
T9882 |
11505-11514 |
VBD |
denotes |
contacted |
T9883 |
11476-11478 |
, |
denotes |
, |
T9884 |
11478-11482 |
IN |
denotes |
from |
T9885 |
11483-11493 |
JJ |
denotes |
horizontal |
T9886 |
11494-11499 |
NNS |
denotes |
cells |
T9887 |
11500-11501 |
-LRB- |
denotes |
( |
T9888 |
11501-11502 |
NN |
denotes |
h |
T9889 |
11502-11503 |
-RRB- |
denotes |
) |
T9890 |
11503-11505 |
, |
denotes |
, |
T9891 |
11515-11518 |
DT |
denotes |
the |
T9892 |
11519-11522 |
NN |
denotes |
rod |
T9893 |
11523-11532 |
RB |
denotes |
laterally |
T9894 |
11532-11533 |
. |
denotes |
. |
T9895 |
11533-11624 |
sentence |
denotes |
An additional process, the postsynaptic bipolar dendrite (b), was situated more centrally. |
T9896 |
11534-11536 |
DT |
denotes |
An |
T9897 |
11548-11555 |
NN |
denotes |
process |
T9898 |
11537-11547 |
JJ |
denotes |
additional |
T9899 |
11600-11608 |
VBN |
denotes |
situated |
T9900 |
11555-11557 |
, |
denotes |
, |
T9901 |
11557-11560 |
DT |
denotes |
the |
T9902 |
11582-11590 |
NN |
denotes |
dendrite |
T9903 |
11561-11573 |
JJ |
denotes |
postsynaptic |
T9904 |
11574-11581 |
JJ |
denotes |
bipolar |
T9905 |
11591-11592 |
-LRB- |
denotes |
( |
T9906 |
11592-11593 |
NN |
denotes |
b |
T9907 |
11593-11594 |
-RRB- |
denotes |
) |
T9908 |
11594-11596 |
, |
denotes |
, |
T9909 |
11596-11599 |
VBD |
denotes |
was |
T9910 |
11609-11613 |
RBR |
denotes |
more |
T9911 |
11614-11623 |
RB |
denotes |
centrally |
T9912 |
11623-11624 |
. |
denotes |
. |
T9913 |
11624-11670 |
sentence |
denotes |
Terminals were filled with synaptic vesicles. |
T9914 |
11625-11634 |
NNS |
denotes |
Terminals |
T9915 |
11640-11646 |
VBN |
denotes |
filled |
T9916 |
11635-11639 |
VBD |
denotes |
were |
T9917 |
11647-11651 |
IN |
denotes |
with |
T9918 |
11652-11660 |
JJ |
denotes |
synaptic |
T9919 |
11661-11669 |
NNS |
denotes |
vesicles |
T9920 |
11669-11670 |
. |
denotes |
. |
T9921 |
11670-11746 |
sentence |
denotes |
One coated vesicle originatinf from the cell membrane was observed (arrow). |
T9922 |
11671-11674 |
CD |
denotes |
One |
T9923 |
11682-11689 |
NN |
denotes |
vesicle |
T9924 |
11675-11681 |
JJ |
denotes |
coated |
T9925 |
11729-11737 |
VBN |
denotes |
observed |
T9926 |
11690-11701 |
VBG |
denotes |
originatinf |
T9927 |
11702-11706 |
IN |
denotes |
from |
T9928 |
11707-11710 |
DT |
denotes |
the |
T9929 |
11716-11724 |
NN |
denotes |
membrane |
T9930 |
11711-11715 |
NN |
denotes |
cell |
T9931 |
11725-11728 |
VBD |
denotes |
was |
T9932 |
11738-11739 |
-LRB- |
denotes |
( |
T9933 |
11739-11744 |
NN |
denotes |
arrow |
T9934 |
11744-11745 |
-RRB- |
denotes |
) |
T9935 |
11745-11746 |
. |
denotes |
. |
T9936 |
11746-11834 |
sentence |
denotes |
(C) In the OPL of Crx-/- retinas, photoreceptor terminals appeared highly disorganized. |
T9937 |
11747-11748 |
-LRB- |
denotes |
( |
T9938 |
11748-11749 |
LS |
denotes |
C |
T9939 |
11805-11813 |
VBD |
denotes |
appeared |
T9940 |
11749-11750 |
-RRB- |
denotes |
) |
T9941 |
11751-11753 |
IN |
denotes |
In |
T9942 |
11754-11757 |
DT |
denotes |
the |
T9943 |
11758-11761 |
NN |
denotes |
OPL |
T9944 |
11762-11764 |
IN |
denotes |
of |
T9945 |
11765-11768 |
NN |
denotes |
Crx |
T9946 |
11772-11779 |
NNS |
denotes |
retinas |
T9947 |
11768-11769 |
SYM |
denotes |
- |
T9948 |
11769-11770 |
HYPH |
denotes |
/ |
T9949 |
11770-11771 |
SYM |
denotes |
- |
T9950 |
11779-11781 |
, |
denotes |
, |
T9951 |
11781-11794 |
NN |
denotes |
photoreceptor |
T9952 |
11795-11804 |
NNS |
denotes |
terminals |
T9953 |
11814-11820 |
RB |
denotes |
highly |
T9954 |
11821-11833 |
JJ |
denotes |
disorganized |
T9955 |
11833-11834 |
. |
denotes |
. |
T9956 |
11834-11995 |
sentence |
denotes |
Putative terminals containing synaptic vesicles and ribbon-like structures were apparent (arrows), suggesting at least limited generation of synapse components. |
T9957 |
11835-11843 |
JJ |
denotes |
Putative |
T9958 |
11844-11853 |
NNS |
denotes |
terminals |
T9959 |
11910-11914 |
VBD |
denotes |
were |
T9960 |
11854-11864 |
VBG |
denotes |
containing |
T9961 |
11865-11873 |
JJ |
denotes |
synaptic |
T9962 |
11874-11882 |
NNS |
denotes |
vesicles |
T9963 |
11883-11886 |
CC |
denotes |
and |
T9964 |
11887-11893 |
NN |
denotes |
ribbon |
T9965 |
11894-11898 |
JJ |
denotes |
like |
T9966 |
11893-11894 |
HYPH |
denotes |
- |
T9967 |
11899-11909 |
NNS |
denotes |
structures |
T9968 |
11915-11923 |
JJ |
denotes |
apparent |
T9969 |
11924-11925 |
-LRB- |
denotes |
( |
T9970 |
11925-11931 |
NNS |
denotes |
arrows |
T9971 |
11931-11932 |
-RRB- |
denotes |
) |
T9972 |
11932-11934 |
, |
denotes |
, |
T9973 |
11934-11944 |
VBG |
denotes |
suggesting |
T9974 |
11945-11947 |
RB |
denotes |
at |
T9975 |
11948-11953 |
RBS |
denotes |
least |
T9976 |
11954-11961 |
JJ |
denotes |
limited |
T9977 |
11962-11972 |
NN |
denotes |
generation |
T9978 |
11973-11975 |
IN |
denotes |
of |
T9979 |
11976-11983 |
NN |
denotes |
synapse |
T9980 |
11984-11994 |
NNS |
denotes |
components |
T9981 |
11994-11995 |
. |
denotes |
. |
T9982 |
11995-12058 |
sentence |
denotes |
However, well formed spherules and pedicles were not observed. |
T9983 |
11996-12003 |
RB |
denotes |
However |
T9984 |
12049-12057 |
VBN |
denotes |
observed |
T9985 |
12003-12005 |
, |
denotes |
, |
T9986 |
12005-12009 |
RB |
denotes |
well |
T9987 |
12010-12016 |
VBN |
denotes |
formed |
T9988 |
12017-12026 |
NNS |
denotes |
spherules |
T9989 |
12027-12030 |
CC |
denotes |
and |
T9990 |
12031-12039 |
NNS |
denotes |
pedicles |
T9991 |
12040-12044 |
VBD |
denotes |
were |
T9992 |
12045-12048 |
RB |
denotes |
not |
T9993 |
12057-12058 |
. |
denotes |
. |
T9994 |
12058-12139 |
sentence |
denotes |
Further, many terminals appeared to contain multiple ribbon-like structures (r). |
T9995 |
12059-12066 |
RB |
denotes |
Further |
T9996 |
12083-12091 |
VBD |
denotes |
appeared |
T9997 |
12066-12068 |
, |
denotes |
, |
T9998 |
12068-12072 |
JJ |
denotes |
many |
T9999 |
12073-12082 |
NNS |
denotes |
terminals |
T10000 |
12092-12094 |
TO |
denotes |
to |
T10001 |
12095-12102 |
VB |
denotes |
contain |
T10002 |
12103-12111 |
JJ |
denotes |
multiple |
T10003 |
12124-12134 |
NNS |
denotes |
structures |
T10004 |
12112-12118 |
NN |
denotes |
ribbon |
T10005 |
12119-12123 |
JJ |
denotes |
like |
T10006 |
12118-12119 |
HYPH |
denotes |
- |
T10007 |
12135-12136 |
-LRB- |
denotes |
( |
T10008 |
12136-12137 |
NN |
denotes |
r |
T10009 |
12137-12138 |
-RRB- |
denotes |
) |
T10010 |
12138-12139 |
. |
denotes |
. |
T10011 |
12139-12307 |
sentence |
denotes |
The majority of these ribbons were not associated with the synaptic membrane, but instead were found free floating and, in some instances, were perinuclear (D, arrow). |
T10012 |
12140-12143 |
DT |
denotes |
The |
T10013 |
12144-12152 |
NN |
denotes |
majority |
T10014 |
12179-12189 |
VBN |
denotes |
associated |
T10015 |
12153-12155 |
IN |
denotes |
of |
T10016 |
12156-12161 |
DT |
denotes |
these |
T10017 |
12162-12169 |
NNS |
denotes |
ribbons |
T10018 |
12170-12174 |
VBD |
denotes |
were |
T10019 |
12175-12178 |
RB |
denotes |
not |
T10020 |
12190-12194 |
IN |
denotes |
with |
T10021 |
12195-12198 |
DT |
denotes |
the |
T10022 |
12208-12216 |
NN |
denotes |
membrane |
T10023 |
12199-12207 |
JJ |
denotes |
synaptic |
T10024 |
12216-12218 |
, |
denotes |
, |
T10025 |
12218-12221 |
CC |
denotes |
but |
T10026 |
12222-12229 |
RB |
denotes |
instead |
T10027 |
12230-12234 |
VBD |
denotes |
were |
T10028 |
12235-12240 |
VBN |
denotes |
found |
T10029 |
12241-12245 |
JJ |
denotes |
free |
T10030 |
12246-12254 |
VBG |
denotes |
floating |
T10031 |
12255-12258 |
CC |
denotes |
and |
T10032 |
12258-12260 |
, |
denotes |
, |
T10033 |
12260-12262 |
IN |
denotes |
in |
T10034 |
12279-12283 |
VBD |
denotes |
were |
T10035 |
12263-12267 |
DT |
denotes |
some |
T10036 |
12268-12277 |
NNS |
denotes |
instances |
T10037 |
12277-12279 |
, |
denotes |
, |
T10038 |
12284-12295 |
JJ |
denotes |
perinuclear |
T10039 |
12296-12297 |
-LRB- |
denotes |
( |
T10040 |
12300-12305 |
NN |
denotes |
arrow |
T10041 |
12297-12298 |
NN |
denotes |
D |
T10042 |
12298-12300 |
, |
denotes |
, |
T10043 |
12305-12306 |
-RRB- |
denotes |
) |
T10044 |
12306-12307 |
. |
denotes |
. |
T10045 |
12307-12367 |
sentence |
denotes |
H, horizontal cell; B, bipolar cell; N, nucleus; r, ribbon. |
T10046 |
12308-12309 |
NN |
denotes |
H |
T10047 |
12309-12311 |
, |
denotes |
, |
T10048 |
12311-12321 |
JJ |
denotes |
horizontal |
T10049 |
12322-12326 |
NN |
denotes |
cell |
T10050 |
12326-12327 |
: |
denotes |
; |
T10051 |
12328-12329 |
NN |
denotes |
B |
T10052 |
12329-12331 |
, |
denotes |
, |
T10053 |
12331-12338 |
JJ |
denotes |
bipolar |
T10054 |
12339-12343 |
NN |
denotes |
cell |
T10055 |
12343-12344 |
: |
denotes |
; |
T10056 |
12345-12346 |
NN |
denotes |
N |
T10057 |
12346-12348 |
, |
denotes |
, |
T10058 |
12348-12355 |
NN |
denotes |
nucleus |
T10059 |
12355-12356 |
: |
denotes |
; |
T10060 |
12357-12358 |
NN |
denotes |
r |
T10061 |
12358-12360 |
, |
denotes |
, |
T10062 |
12360-12366 |
NN |
denotes |
ribbon |
T10063 |
12366-12367 |
. |
denotes |
. |
T10064 |
12367-12445 |
sentence |
denotes |
(A) Scale bar = 500 nm, (B) Scale bar = 250 nm, (C and D) Scale bar = 500 nm. |
T10065 |
12368-12369 |
-LRB- |
denotes |
( |
T10066 |
12369-12370 |
LS |
denotes |
A |
T10067 |
12388-12390 |
NN |
denotes |
nm |
T10068 |
12370-12371 |
-RRB- |
denotes |
) |
T10069 |
12372-12377 |
NN |
denotes |
Scale |
T10070 |
12378-12381 |
NN |
denotes |
bar |
T10071 |
12382-12383 |
SYM |
denotes |
= |
T10072 |
12384-12387 |
CD |
denotes |
500 |
T10073 |
12442-12444 |
NN |
denotes |
nm |
T10074 |
12390-12392 |
, |
denotes |
, |
T10075 |
12392-12393 |
-LRB- |
denotes |
( |
T10076 |
12393-12394 |
LS |
denotes |
B |
T10077 |
12412-12414 |
NN |
denotes |
nm |
T10078 |
12394-12395 |
-RRB- |
denotes |
) |
T10079 |
12396-12401 |
NN |
denotes |
Scale |
T10080 |
12402-12405 |
NN |
denotes |
bar |
T10081 |
12406-12407 |
SYM |
denotes |
= |
T10082 |
12408-12411 |
CD |
denotes |
250 |
T10083 |
12414-12416 |
, |
denotes |
, |
T10084 |
12416-12417 |
-LRB- |
denotes |
( |
T10085 |
12417-12418 |
LS |
denotes |
C |
T10086 |
12419-12422 |
CC |
denotes |
and |
T10087 |
12423-12424 |
LS |
denotes |
D |
T10088 |
12424-12425 |
-RRB- |
denotes |
) |
T10089 |
12426-12431 |
NN |
denotes |
Scale |
T10090 |
12432-12435 |
NN |
denotes |
bar |
T10091 |
12436-12437 |
SYM |
denotes |
= |
T10092 |
12438-12441 |
CD |
denotes |
500 |
T10093 |
12444-12445 |
. |
denotes |
. |
T2556 |
968-970 |
, |
denotes |
, |
T2557 |
970-972 |
DT |
denotes |
an |
T2558 |
979-986 |
NN |
denotes |
segment |
T2559 |
973-978 |
JJ |
denotes |
inner |
T2560 |
987-997 |
VBG |
denotes |
undergoing |
T2561 |
998-1003 |
NN |
denotes |
lysis |
T2562 |
1004-1007 |
VBD |
denotes |
was |
T2563 |
1013-1015 |
, |
denotes |
, |
T2564 |
1015-1024 |
VBG |
denotes |
appearing |
T2565 |
1025-1032 |
VBN |
denotes |
swollen |
T2566 |
1033-1035 |
CC |
denotes |
or |
T2567 |
1036-1040 |
IN |
denotes |
with |
T2568 |
1041-1049 |
NNS |
denotes |
vacuoles |
T2569 |
1050-1053 |
CC |
denotes |
and |
T2570 |
1054-1061 |
VBN |
denotes |
swollen |
T2571 |
1062-1074 |
NNS |
denotes |
mitochondria |
T2572 |
1075-1076 |
-LRB- |
denotes |
( |
T2573 |
1085-1090 |
VBN |
denotes |
shown |
T2574 |
1076-1080 |
NNS |
denotes |
data |
T2575 |
1081-1084 |
RB |
denotes |
not |
T2576 |
1090-1091 |
-RRB- |
denotes |
) |
T2577 |
1091-1092 |
. |
denotes |
. |
T2578 |
1092-1093 |
sentence |
denotes |
|
T2579 |
1653-1654 |
sentence |
denotes |
P |
T2580 |
1653-1654 |
NN |
denotes |
P |
T2581 |
1654-1655 |
sentence |
denotes |
h |
T2582 |
1654-1655 |
NN |
denotes |
h |
T2583 |
1655-1657 |
sentence |
denotes |
ot |
T2584 |
1655-1656 |
NN |
denotes |
o |
T2585 |
1656-1657 |
JJ |
denotes |
t |
T2586 |
1657-1668 |
sentence |
denotes |
oreceptor i |
T2587 |
1657-1658 |
NN |
denotes |
o |
T2588 |
1658-1659 |
JJ |
denotes |
r |
T2589 |
1659-1660 |
JJ |
denotes |
e |
T2548 |
939-945 |
NN |
denotes |
Figure |
T2549 |
948-951 |
CC |
denotes |
and |
T2550 |
952-953 |
CD |
denotes |
2 |
T2551 |
953-954 |
-RRB- |
denotes |
) |
T2552 |
954-955 |
. |
denotes |
. |
T2553 |
955-1092 |
sentence |
denotes |
Occasionally, an inner segment undergoing lysis was noted, appearing swollen or with vacuoles and swollen mitochondria (data not shown). |
T2554 |
956-968 |
RB |
denotes |
Occasionally |
T2555 |
1008-1013 |
VBN |
denotes |
noted |
T2590 |
1660-1666 |
NN |
denotes |
ceptor |
T2591 |
1667-1668 |
NNS |
denotes |
i |
T2592 |
1668-1669 |
sentence |
denotes |
n |
T2593 |
1668-1669 |
CC |
denotes |
n |
T2594 |
1669-1680 |
sentence |
denotes |
ner segment |
T2595 |
1669-1670 |
NN |
denotes |
n |
T2596 |
1670-1672 |
NN |
denotes |
er |
T2597 |
1673-1680 |
NN |
denotes |
segment |
T2598 |
1680-1688 |
sentence |
denotes |
s and ou |
T2599 |
1680-1681 |
NNS |
denotes |
s |
T2600 |
1682-1683 |
NNS |
denotes |
a |
T2601 |
1683-1685 |
VBN |
denotes |
nd |
T2602 |
1686-1687 |
NN |
denotes |
o |
T2603 |
1687-1688 |
NN |
denotes |
u |
T2604 |
1688-1690 |
sentence |
denotes |
te |
T2605 |
1688-1690 |
JJ |
denotes |
te |
T2606 |
1690-1700 |
sentence |
denotes |
r segments |
T2607 |
1690-1691 |
JJ |
denotes |
r |
T2608 |
1692-1700 |
NNS |
denotes |
segments |
T2609 |
1700-1704 |
sentence |
denotes |
are |
T2610 |
1703-1704 |
NN |
denotes |
e |
T2611 |
1701-1703 |
JJ |
denotes |
ar |
T2612 |
1704-1705 |
sentence |
denotes |
|
T2613 |
1705-1848 |
sentence |
denotes |
joined by a non-motile connecting cilium that exhibits a characteristic 9 + 0 arrangement of microtubule doublets when viewed in cross-section. |
T2614 |
1705-1711 |
VBN |
denotes |
joined |
T2615 |
1712-1714 |
IN |
denotes |
by |
T2616 |
1715-1716 |
DT |
denotes |
a |
T2617 |
1739-1745 |
NN |
denotes |
cilium |
T2618 |
1717-1727 |
JJ |
denotes |
non-motile |
T2619 |
1728-1738 |
JJ |
denotes |
connecting |
T2620 |
1746-1750 |
WDT |
denotes |
that |
T2621 |
1751-1759 |
VBZ |
denotes |
exhibits |
T2622 |
1760-1761 |
DT |
denotes |
a |
T2623 |
1783-1794 |
NN |
denotes |
arrangement |
T2624 |
1762-1776 |
JJ |
denotes |
characteristic |
T2625 |
1777-1778 |
CD |
denotes |
9 |
T2626 |
1781-1782 |
CD |
denotes |
0 |
T2627 |
1779-1780 |
SYM |
denotes |
+ |
T2628 |
1795-1797 |
IN |
denotes |
of |
T2629 |
1798-1809 |
NN |
denotes |
microtubule |
T2630 |
1810-1818 |
NNS |
denotes |
doublets |
T2631 |
1819-1823 |
WRB |
denotes |
when |
T2632 |
1824-1830 |
VBN |
denotes |
viewed |
T2633 |
1831-1833 |
IN |
denotes |
in |
T2634 |
1834-1847 |
NN |
denotes |
cross-section |
T2635 |
1847-1848 |
. |
denotes |
. |
T2636 |
1848-1950 |
sentence |
denotes |
At P21, in Crx-/- retinas, numerous cross sections of connecting cilia were noted (Figure 3A and 3B). |
T2637 |
1849-1851 |
IN |
denotes |
At |
T2638 |
1925-1930 |
VBN |
denotes |
noted |
T2639 |
1852-1855 |
NN |
denotes |
P21 |
T2640 |
1855-1857 |
, |
denotes |
, |
T2747 |
2387-2394 |
RB |
denotes |
Further |
T2748 |
2452-2460 |
VBD |
denotes |
appeared |
T2749 |
2394-2396 |
, |
denotes |
, |
T2750 |
2396-2398 |
IN |
denotes |
in |
T2751 |
2399-2402 |
NN |
denotes |
Crx |
T2752 |
2406-2413 |
NNS |
denotes |
retinas |
T2753 |
2402-2403 |
SYM |
denotes |
- |
T2754 |
2403-2404 |
HYPH |
denotes |
/ |
T2755 |
2404-2405 |
SYM |
denotes |
- |
T2756 |
2414-2417 |
DT |
denotes |
the |
T2757 |
2436-2446 |
NN |
denotes |
epithelium |
T2758 |
2418-2425 |
NN |
denotes |
retinal |
T2759 |
2426-2435 |
VBN |
denotes |
pigmented |
T2760 |
2447-2448 |
-LRB- |
denotes |
( |
T2761 |
2448-2450 |
NN |
denotes |
PE |
T2762 |
2450-2451 |
-RRB- |
denotes |
) |
T2763 |
2461-2467 |
JJ |
denotes |
normal |
T2764 |
2467-2469 |
, |
denotes |
, |
T2765 |
2469-2471 |
RB |
denotes |
at |
T2766 |
2472-2477 |
RBS |
denotes |
least |
T2767 |
2478-2480 |
IN |
denotes |
up |
T2768 |
2481-2483 |
IN |
denotes |
to |
T2769 |
2484-2487 |
NN |
denotes |
P21 |
T2770 |
2488-2489 |
-LRB- |
denotes |
( |
T2771 |
2498-2503 |
VBN |
denotes |
shown |
T2772 |
2489-2493 |
NNS |
denotes |
data |
T2773 |
2494-2497 |
RB |
denotes |
not |
T2774 |
2503-2504 |
-RRB- |
denotes |
) |
T2775 |
2504-2506 |
, |
denotes |
, |
T2776 |
2506-2509 |
DT |
denotes |
the |
T2777 |
2517-2520 |
NN |
denotes |
age |
T2778 |
2510-2516 |
JJS |
denotes |
oldest |
T2779 |
2521-2529 |
VBN |
denotes |
examined |
T2780 |
2529-2530 |
. |
denotes |
. |
T2781 |
2530-2531 |
sentence |
denotes |
|
T2782 |
3700-3722 |
sentence |
denotes |
In addition to the com |
T2783 |
3700-3702 |
IN |
denotes |
In |
T2784 |
3703-3704 |
DT |
denotes |
a |
T2785 |
3704-3706 |
VBN |
denotes |
dd |
T2786 |
3706-3707 |
VBG |
denotes |
i |
T2787 |
3707-3709 |
JJ |
denotes |
ti |
T2788 |
3709-3710 |
JJ |
denotes |
o |
T2789 |
3710-3711 |
NN |
denotes |
n |
T2790 |
3712-3713 |
NN |
denotes |
t |
T2791 |
3713-3714 |
IN |
denotes |
o |
T2792 |
3715-3716 |
NN |
denotes |
t |
T2793 |
3716-3717 |
IN |
denotes |
h |
T2794 |
3717-3718 |
JJ |
denotes |
e |
T2795 |
3719-3720 |
NNS |
denotes |
c |
T2796 |
3720-3721 |
NN |
denotes |
o |
T2797 |
3721-3722 |
IN |
denotes |
m |
T2798 |
3722-3726 |
sentence |
denotes |
plet |
T2799 |
3722-3723 |
NN |
denotes |
p |
T2800 |
3723-3724 |
JJ |
denotes |
l |
T2801 |
3724-3725 |
NN |
denotes |
e |
T2802 |
3725-3726 |
NNS |
denotes |
t |
T2803 |
3726-3729 |
sentence |
denotes |
e a |
T2804 |
3726-3727 |
NN |
denotes |
e |
T2805 |
3728-3729 |
NN |
denotes |
a |
T2806 |
3729-3736 |
sentence |
denotes |
bsence |
T2807 |
3729-3731 |
JJ |
denotes |
bs |
T2808 |
3731-3732 |
NNS |
denotes |
e |
T2809 |
3732-3733 |
CD |
denotes |
n |
T2810 |
3733-3735 |
NNS |
denotes |
ce |
T2811 |
3736-3740 |
sentence |
denotes |
of o |
T2812 |
3736-3737 |
VBZ |
denotes |
o |
T2813 |
3737-3738 |
IN |
denotes |
f |
T2814 |
3739-3740 |
VBN |
denotes |
o |
T2815 |
3740-3839 |
sentence |
denotes |
uter segments, Crx-/- retinas exhibited three other notable pathologies in the outer segment layer. |
T2816 |
3770-3779 |
VBD |
denotes |
exhibited |
T2817 |
3740-3744 |
JJ |
denotes |
uter |
T2818 |
3745-3753 |
NNS |
denotes |
segments |
T2819 |
3753-3755 |
, |
denotes |
, |
T2820 |
3755-3758 |
NN |
denotes |
Crx |
T2821 |
3762-3769 |
NNS |
denotes |
retinas |
T2822 |
3758-3759 |
SYM |
denotes |
- |
T2823 |
3759-3760 |
HYPH |
denotes |
/ |
T2824 |
3760-3761 |
SYM |
denotes |
- |
T2825 |
3780-3785 |
CD |
denotes |
three |
T2826 |
3800-3811 |
NNS |
denotes |
pathologies |
T2827 |
3786-3791 |
JJ |
denotes |
other |
T2828 |
3792-3799 |
JJ |
denotes |
notable |
T2829 |
3812-3814 |
IN |
denotes |
in |
T2830 |
3815-3818 |
DT |
denotes |
the |
T2831 |
3833-3838 |
NN |
denotes |
layer |
T2832 |
3819-3824 |
JJ |
denotes |
outer |
T2833 |
3825-3832 |
NN |
denotes |
segment |
T2834 |
3838-3839 |
. |
denotes |
. |
T2835 |
3839-3926 |
sentence |
denotes |
First, an abnormal deposition of matrix of unknown identity was noted (Figure 3A, mx). |
T3258 |
5929-5935 |
NN |
denotes |
Figure |
T3259 |
5936-5938 |
NN |
denotes |
4F |
T3260 |
5938-5940 |
, |
denotes |
, |
T3261 |
5942-5943 |
-RRB- |
denotes |
) |
T3262 |
5943-5944 |
. |
denotes |
. |
T3263 |
5944-6129 |
sentence |
denotes |
Serial examination of Crx-/- photoreceptors at P7, P10, P14, and P21 by TEM, demonstrated a distinctive lack of any structure interpretable as orderly stacks of discs or forming discs. |
T3264 |
5945-5951 |
JJ |
denotes |
Serial |
T3265 |
5952-5963 |
NN |
denotes |
examination |
T3266 |
6022-6034 |
VBD |
denotes |
demonstrated |
T3267 |
5964-5966 |
IN |
denotes |
of |
T3268 |
5967-5970 |
NN |
denotes |
Crx |
T3269 |
5974-5988 |
NNS |
denotes |
photoreceptors |
T3270 |
5970-5971 |
SYM |
denotes |
- |
T3271 |
5971-5972 |
HYPH |
denotes |
/ |
T3272 |
5972-5973 |
SYM |
denotes |
- |
T3273 |
5989-5991 |
IN |
denotes |
at |
T3274 |
5992-5994 |
NN |
denotes |
P7 |
T3275 |
5994-5996 |
, |
denotes |
, |
T3345 |
7653-7654 |
sentence |
denotes |
y |
T3346 |
7653-7654 |
JJ |
denotes |
y |
T3347 |
7654-7657 |
sentence |
denotes |
, t |
T3348 |
7654-7656 |
, |
denotes |
, |
T3349 |
7656-7657 |
JJ |
denotes |
t |
T3350 |
7657-7660 |
sentence |
denotes |
he |
T3351 |
7657-7659 |
VBP |
denotes |
he |
T3352 |
7660-7663 |
sentence |
denotes |
mor |
T3353 |
7660-7663 |
RBR |
denotes |
mor |
T3354 |
7663-7667 |
sentence |
denotes |
phol |
T3355 |
7663-7665 |
NNS |
denotes |
ph |
T3356 |
7665-7666 |
IN |
denotes |
o |
T3357 |
7666-7667 |
NN |
denotes |
l |
T3358 |
7667-7669 |
sentence |
denotes |
og |
T3359 |
7667-7668 |
NN |
denotes |
o |
T3360 |
7668-7669 |
VBG |
denotes |
g |
T3361 |
7669-7672 |
sentence |
denotes |
y o |
T3362 |
7669-7670 |
JJ |
denotes |
y |
T3363 |
7671-7672 |
RB |
denotes |
o |
T3364 |
7672-7772 |
sentence |
denotes |
f the malformed Crx-/- photoreceptors was compared to rhodopsin-/- and peripherin-/- photoreceptors. |
T3365 |
7714-7722 |
VBN |
denotes |
compared |
T3366 |
7672-7673 |
IN |
denotes |
f |
T3367 |
7674-7677 |
DT |
denotes |
the |
T3368 |
7695-7709 |
NNS |
denotes |
photoreceptors |
T3369 |
7678-7687 |
JJ |
denotes |
malformed |
T3370 |
7688-7691 |
NN |
denotes |
Crx |
T3371 |
7691-7692 |
SYM |
denotes |
- |
T3372 |
7692-7693 |
HYPH |
denotes |
/ |
T3373 |
7693-7694 |
SYM |
denotes |
- |
T3374 |
7710-7713 |
VBD |
denotes |
was |
T3375 |
7723-7725 |
IN |
denotes |
to |
T3376 |
7726-7735 |
NN |
denotes |
rhodopsin |
T3377 |
7757-7771 |
NNS |
denotes |
photoreceptors |
T3378 |
7735-7736 |
SYM |
denotes |
- |
T3379 |
7736-7737 |
HYPH |
denotes |
/ |
T3380 |
7737-7738 |
SYM |
denotes |
- |
T3381 |
7739-7742 |
CC |
denotes |
and |
T3382 |
7743-7753 |
NN |
denotes |
peripherin |
T3383 |
7753-7754 |
SYM |
denotes |
- |
T3384 |
7754-7755 |
HYPH |
denotes |
/ |
T3385 |
7755-7756 |
SYM |
denotes |
- |
T3386 |
7771-7772 |
. |
denotes |
. |
T3387 |
7772-7916 |
sentence |
denotes |
Rhodopsin and peripherin are two photoreceptor-specific genes whose expression is significantly downregulated in the Crx-/- retinae [10,34,35]. |
R1144 |
T2359 |
T2360 |
amod |
Multiple,pathologies |
R1145 |
T2361 |
T2360 |
prep |
in,pathologies |
R1146 |
T2362 |
T2363 |
det |
the,layer |
R1147 |
T2363 |
T2361 |
pobj |
layer,in |
R1148 |
T2364 |
T2365 |
amod |
outer,segment |
R1149 |
T2365 |
T2363 |
compound |
segment,layer |
R1150 |
T2366 |
T2360 |
prep |
in,pathologies |
R1151 |
T2367 |
T2368 |
nmod |
Crx,mice |
R1152 |
T2368 |
T2366 |
pobj |
mice,in |
R1153 |
T2369 |
T2367 |
punct |
-,Crx |
R1154 |
T2370 |
T2367 |
punct |
/,Crx |
R1155 |
T2371 |
T2367 |
punct |
-,Crx |
R1156 |
T2373 |
T2374 |
det |
A,protocol |
R1157 |
T2374 |
T2379 |
nsubjpass |
protocol,used |
R1158 |
T2375 |
T2374 |
amod |
standard,protocol |
R1159 |
T2376 |
T2374 |
amod |
knock,protocol |
R1160 |
T2377 |
T2376 |
punct |
-,knock |
R1161 |
T2378 |
T2376 |
prt |
out,knock |
R1162 |
T2380 |
T2379 |
auxpass |
was,used |
R1163 |
T2381 |
T2382 |
aux |
to,generate |
R1164 |
T2382 |
T2379 |
advcl |
generate,used |
R1165 |
T2383 |
T2382 |
dobj |
mice,generate |
R1166 |
T2384 |
T2385 |
prep |
in,targeted |
R1167 |
T2385 |
T2383 |
relcl |
targeted,mice |
R1168 |
T2386 |
T2384 |
pobj |
which,in |
R1169 |
T2387 |
T2388 |
det |
the,homeodomain |
R1170 |
T2388 |
T2385 |
nsubjpass |
homeodomain,targeted |
R1171 |
T2389 |
T2388 |
prep |
of,homeodomain |
R1172 |
T2390 |
T2389 |
pobj |
Crx,of |
R1173 |
T2391 |
T2390 |
punct |
-,Crx |
R1174 |
T2392 |
T2390 |
punct |
/,Crx |
R1175 |
T2393 |
T2390 |
punct |
-,Crx |
R1176 |
T2394 |
T2385 |
auxpass |
was,targeted |
R1177 |
T2395 |
T2385 |
cc |
and,targeted |
R1178 |
T2396 |
T2385 |
conj |
deleted,targeted |
R1179 |
T2397 |
T2379 |
punct |
.,used |
R1180 |
T2399 |
T2400 |
nsubjpass |
Generation,reported |
R1181 |
T2401 |
T2399 |
prep |
of,Generation |
R1182 |
T2402 |
T2403 |
det |
these,mice |
R1183 |
T2403 |
T2401 |
pobj |
mice,of |
R1184 |
T2404 |
T2403 |
nmod |
Crx,mice |
R1185 |
T2405 |
T2404 |
punct |
-,Crx |
R1186 |
T2406 |
T2404 |
punct |
/,Crx |
R1187 |
T2407 |
T2404 |
punct |
-,Crx |
R1188 |
T2408 |
T2400 |
aux |
has,reported |
R1189 |
T2409 |
T2400 |
auxpass |
been,reported |
R1190 |
T2410 |
T2400 |
advmod |
elsewhere,reported |
R1191 |
T2411 |
T2412 |
punct |
[,34 |
R1192 |
T2412 |
T2400 |
parataxis |
34,reported |
R1193 |
T2413 |
T2412 |
punct |
],34 |
R1194 |
T2414 |
T2400 |
punct |
.,reported |
R1195 |
T2416 |
T2417 |
prep |
In,examined |
R1196 |
T2418 |
T2419 |
det |
this,study |
R1197 |
T2419 |
T2416 |
pobj |
study,In |
R1198 |
T2420 |
T2417 |
punct |
", ",examined |
R1199 |
T2421 |
T2417 |
prep |
in,examined |
R1200 |
T2422 |
T2421 |
pobj |
order,in |
R1201 |
T2423 |
T2424 |
aux |
to,characterize |
R1202 |
T2424 |
T2422 |
acl |
characterize,order |
R1203 |
T2425 |
T2424 |
advmod |
further,characterize |
R1204 |
T2426 |
T2427 |
det |
the,role |
R1205 |
T2427 |
T2424 |
dobj |
role,characterize |
R1206 |
T2428 |
T2427 |
prep |
of,role |
R1207 |
T2429 |
T2428 |
pobj |
Crx,of |
R1208 |
T2430 |
T2427 |
prep |
in,role |
R1209 |
T2431 |
T2432 |
compound |
photoreceptor,morphogenesis |
R1210 |
T2432 |
T2430 |
pobj |
morphogenesis,in |
R1211 |
T2433 |
T2417 |
punct |
", ",examined |
R1212 |
T2434 |
T2435 |
det |
the,retinae |
R1213 |
T2435 |
T2417 |
nsubjpass |
retinae,examined |
R1214 |
T2436 |
T2435 |
amod |
outer,retinae |
R1215 |
T2437 |
T2435 |
prep |
from,retinae |
R1216 |
T2438 |
T2439 |
nmod |
Crx,mice |
R1217 |
T2439 |
T2437 |
pobj |
mice,from |
R1218 |
T2440 |
T2438 |
punct |
-,Crx |
R1219 |
T2441 |
T2438 |
punct |
/,Crx |
R1220 |
T2442 |
T2438 |
punct |
-,Crx |
R1221 |
T2443 |
T2417 |
auxpass |
were,examined |
R1222 |
T2444 |
T2417 |
advcl |
using,examined |
R1223 |
T2445 |
T2446 |
compound |
transmission,microscopy |
R1224 |
T2446 |
T2444 |
dobj |
microscopy,using |
R1225 |
T2447 |
T2446 |
compound |
electron,microscopy |
R1226 |
T2448 |
T2417 |
punct |
.,examined |
R1227 |
T2450 |
T2451 |
prep |
At,were |
R1228 |
T2452 |
T2453 |
amod |
postnatal,day |
R1229 |
T2453 |
T2450 |
pobj |
day,At |
R1230 |
T2454 |
T2453 |
nummod |
21,day |
R1231 |
T2455 |
T2453 |
punct |
(,day |
R1232 |
T2456 |
T2453 |
appos |
P21,day |
R1233 |
T2457 |
T2451 |
punct |
),were |
R1234 |
T2458 |
T2451 |
punct |
", ",were |
R1235 |
T2459 |
T2460 |
advmod |
when,exhibited |
R1236 |
T2460 |
T2451 |
advcl |
exhibited,were |
R1237 |
T2461 |
T2462 |
nmod |
Crx,photoreceptors |
R1238 |
T2462 |
T2460 |
nsubj |
photoreceptors,exhibited |
R1239 |
T2463 |
T2461 |
punct |
+,Crx |
R1240 |
T2464 |
T2461 |
punct |
/,Crx |
R1241 |
T2465 |
T2461 |
punct |
+,Crx |
R1242 |
T2466 |
T2467 |
amod |
robust,segments |
R1243 |
T2467 |
T2460 |
dobj |
segments,exhibited |
R1244 |
T2468 |
T2467 |
amod |
outer,segments |
R1245 |
T2469 |
T2470 |
punct |
(,os |
R1246 |
T2470 |
T2460 |
parataxis |
os,exhibited |
R1247 |
T2471 |
T2472 |
compound |
Figure,1A |
R1248 |
T2472 |
T2470 |
dep |
1A,os |
R1249 |
T2473 |
T2470 |
punct |
", ",os |
R1250 |
T2474 |
T2470 |
punct |
),os |
R1251 |
T2475 |
T2451 |
punct |
", ",were |
R1252 |
T2476 |
T2477 |
nmod |
Crx,retinas |
R1253 |
T2477 |
T2451 |
nsubj |
retinas,were |
R1254 |
T2478 |
T2476 |
punct |
-,Crx |
R1255 |
T2479 |
T2476 |
punct |
/,Crx |
R1256 |
T2480 |
T2476 |
punct |
-,Crx |
R1257 |
T2481 |
T2451 |
prep |
without,were |
R1258 |
T2482 |
T2483 |
det |
a,layer |
R1259 |
T2483 |
T2481 |
pobj |
layer,without |
R1260 |
T2484 |
T2483 |
amod |
recognizable,layer |
R1261 |
T2485 |
T2486 |
amod |
outer,segment |
R1262 |
T2486 |
T2483 |
compound |
segment,layer |
R1263 |
T2487 |
T2488 |
punct |
(,Figure |
R1264 |
T2488 |
T2451 |
parataxis |
Figure,were |
R1265 |
T2489 |
T2488 |
nummod |
1B,Figure |
R1266 |
T2490 |
T2488 |
punct |
),Figure |
R1267 |
T2491 |
T2451 |
punct |
.,were |
R1268 |
T2493 |
T2494 |
nmod |
Crx,photoreceptors |
R1269 |
T2494 |
T2498 |
nsubj |
photoreceptors,had |
R1270 |
T2495 |
T2493 |
punct |
-,Crx |
R1271 |
T2496 |
T2493 |
punct |
/,Crx |
R1272 |
T2497 |
T2493 |
punct |
-,Crx |
R1273 |
T2499 |
T2500 |
amod |
inner,segments |
R1274 |
T2500 |
T2498 |
dobj |
segments,had |
R1275 |
T2501 |
T2498 |
punct |
", ",had |
R1276 |
T2502 |
T2498 |
advcl |
demonstrating,had |
R1277 |
T2503 |
T2504 |
advmod |
at,least |
R1278 |
T2504 |
T2505 |
advmod |
least,limited |
R1279 |
T2505 |
T2506 |
amod |
limited,polarization |
R1280 |
T2506 |
T2502 |
dobj |
polarization,demonstrating |
R1281 |
T2507 |
T2506 |
compound |
photoreceptor,polarization |
R1282 |
T2508 |
T2506 |
prep |
in,polarization |
R1283 |
T2509 |
T2510 |
det |
the,mutant |
R1284 |
T2510 |
T2508 |
pobj |
mutant,in |
R1285 |
T2511 |
T2510 |
compound |
Crx,mutant |
R1286 |
T2512 |
T2498 |
punct |
", ",had |
R1287 |
T2513 |
T2498 |
cc |
but,had |
R1288 |
T2514 |
T2515 |
det |
the,segments |
R1289 |
T2515 |
T2517 |
nsubj |
segments,were |
R1290 |
T2516 |
T2515 |
amod |
inner,segments |
R1291 |
T2517 |
T2498 |
conj |
were,had |
R1292 |
T2518 |
T2519 |
advmod |
extremely,short |
R1293 |
T2519 |
T2517 |
acomp |
short,were |
R1294 |
T2520 |
T2521 |
punct |
(,Figure |
R1295 |
T2521 |
T2517 |
parataxis |
Figure,were |
R1296 |
T2522 |
T2521 |
nummod |
2,Figure |
R1297 |
T2523 |
T2521 |
punct |
),Figure |
R1298 |
T2524 |
T2517 |
punct |
.,were |
R1299 |
T2526 |
T2527 |
advmod |
Furthermore,showed |
R1300 |
T2528 |
T2527 |
punct |
", ",showed |
R1301 |
T2529 |
T2530 |
det |
the,majority |
R1302 |
T2530 |
T2527 |
nsubj |
majority,showed |
R1303 |
T2531 |
T2530 |
prep |
of,majority |
R1304 |
T2532 |
T2533 |
amod |
inner,segments |
R1305 |
T2533 |
T2531 |
pobj |
segments,of |
R1306 |
T2534 |
T2535 |
det |
some,differentiation |
R1307 |
T2535 |
T2527 |
dobj |
differentiation,showed |
R1308 |
T2536 |
T2535 |
amod |
morphological,differentiation |
R1309 |
T2537 |
T2527 |
punct |
", ",showed |
R1310 |
T2538 |
T2527 |
advcl |
having,showed |
R1311 |
T2539 |
T2540 |
advmod |
approximately,many |
R1312 |
T2540 |
T2542 |
amod |
many,mitochondria |
R1313 |
T2541 |
T2540 |
advmod |
as,many |
R1314 |
T2542 |
T2538 |
dobj |
mitochondria,having |
R1315 |
T2543 |
T2542 |
prep |
as,mitochondria |
R1316 |
T2544 |
T2545 |
det |
the,control |
R1317 |
T2545 |
T2543 |
pobj |
control,as |
R1318 |
T2546 |
T2547 |
punct |
(,1 |
R1319 |
T2547 |
T2538 |
parataxis |
1,having |
R1320 |
T2548 |
T2547 |
nmod |
Figure,1 |
R1321 |
T2549 |
T2547 |
cc |
and,1 |
R1322 |
T2550 |
T2547 |
conj |
2,1 |
R1323 |
T2551 |
T2547 |
punct |
),1 |
R1324 |
T2552 |
T2527 |
punct |
.,showed |
R1325 |
T2554 |
T2555 |
advmod |
Occasionally,noted |
R1326 |
T2556 |
T2555 |
punct |
", ",noted |
R1327 |
T2557 |
T2558 |
det |
an,segment |
R1328 |
T2558 |
T2555 |
nsubjpass |
segment,noted |
R1329 |
T2559 |
T2558 |
amod |
inner,segment |
R1330 |
T2560 |
T2558 |
acl |
undergoing,segment |
R1331 |
T2561 |
T2560 |
dobj |
lysis,undergoing |
R1332 |
T2562 |
T2555 |
auxpass |
was,noted |
R1333 |
T2563 |
T2555 |
punct |
", ",noted |
R1334 |
T2564 |
T2555 |
advcl |
appearing,noted |
R1335 |
T2565 |
T2564 |
oprd |
swollen,appearing |
R1336 |
T2566 |
T2565 |
cc |
or,swollen |
R1337 |
T2567 |
T2565 |
conj |
with,swollen |
R1338 |
T2568 |
T2567 |
pobj |
vacuoles,with |
R1339 |
T2569 |
T2568 |
cc |
and,vacuoles |
R1340 |
T2570 |
T2571 |
amod |
swollen,mitochondria |
R1341 |
T2571 |
T2568 |
conj |
mitochondria,vacuoles |
R1342 |
T2572 |
T2573 |
punct |
(,shown |
R1343 |
T2573 |
T2564 |
parataxis |
shown,appearing |
R1344 |
T2574 |
T2573 |
nsubj |
data,shown |
R1345 |
T2575 |
T2573 |
neg |
not,shown |
R1346 |
T2576 |
T2573 |
punct |
),shown |
R1347 |
T2577 |
T2555 |
punct |
.,noted |
R1389 |
T2654 |
T2638 |
auxpass |
were,noted |
R1390 |
T2655 |
T2656 |
punct |
(,3A |
R1391 |
T2656 |
T2638 |
parataxis |
3A,noted |
R1392 |
T2657 |
T2656 |
nmod |
Figure,3A |
R1393 |
T2658 |
T2656 |
cc |
and,3A |
R1394 |
T2659 |
T2656 |
conj |
3B,3A |
R1395 |
T2660 |
T2656 |
punct |
),3A |
R1396 |
T2661 |
T2638 |
punct |
.,noted |
R1397 |
T2663 |
T2664 |
advmod |
Sporadically,contained |
R1398 |
T2665 |
T2664 |
punct |
", ",contained |
R1399 |
T2666 |
T2667 |
amod |
connecting,cilia |
R1400 |
T2667 |
T2664 |
nsubj |
cilia,contained |
R1401 |
T2668 |
T2664 |
dobj |
other,contained |
R1402 |
T2669 |
T2668 |
prep |
than,other |
R1403 |
T2670 |
T2671 |
det |
the,complement |
R1404 |
T2671 |
T2669 |
pobj |
complement,than |
R1405 |
T2672 |
T2671 |
amod |
typical,complement |
R1406 |
T2673 |
T2671 |
prep |
of,complement |
R1407 |
T2674 |
T2675 |
compound |
microtubule,doublets |
R1408 |
T2675 |
T2673 |
pobj |
doublets,of |
R1409 |
T2676 |
T2664 |
punct |
.,contained |
R1410 |
T2678 |
T2679 |
prep |
For,shows |
R1411 |
T2680 |
T2678 |
pobj |
example,For |
R1412 |
T2681 |
T2679 |
punct |
", ",shows |
R1413 |
T2682 |
T2679 |
prep |
in,shows |
R1414 |
T2683 |
T2684 |
compound |
Figure,3A |
R1415 |
T2684 |
T2682 |
pobj |
3A,in |
R1416 |
T2685 |
T2679 |
punct |
", ",shows |
R1417 |
T2686 |
T2687 |
det |
the,cilium |
R1418 |
T2687 |
T2679 |
nsubj |
cilium,shows |
R1419 |
T2688 |
T2687 |
amod |
connecting,cilium |
R1420 |
T2689 |
T2687 |
acl |
labelled,cilium |
R1421 |
T2690 |
T2689 |
agent |
by,labelled |
R1422 |
T2691 |
T2690 |
pobj |
arrowhead,by |
R1423 |
T2692 |
T2691 |
nummod |
1,arrowhead |
R1424 |
T2693 |
T2679 |
punct |
", ",shows |
R1425 |
T2694 |
T2695 |
nummod |
7,0 |
R1426 |
T2695 |
T2697 |
nummod |
0,doublets |
R1427 |
T2696 |
T2695 |
punct |
+,0 |
R1428 |
T2697 |
T2679 |
dobj |
doublets,shows |
R1429 |
T2698 |
T2679 |
punct |
.,shows |
R1430 |
T2700 |
T2701 |
det |
The,majority |
R1431 |
T2701 |
T2702 |
nsubj |
majority,exhibited |
R1432 |
T2703 |
T2704 |
det |
the,doublets |
R1433 |
T2704 |
T2702 |
dobj |
doublets,exhibited |
R1434 |
T2705 |
T2704 |
amod |
characteristic,doublets |
R1435 |
T2706 |
T2707 |
nummod |
9,0 |
R1436 |
T2707 |
T2704 |
nummod |
0,doublets |
R1437 |
T2708 |
T2707 |
punct |
+,0 |
R1438 |
T2709 |
T2710 |
punct |
(,2 |
R1439 |
T2710 |
T2702 |
parataxis |
2,exhibited |
R1440 |
T2711 |
T2710 |
nmod |
arrowhead,2 |
R1441 |
T2712 |
T2710 |
cc |
and,2 |
R1442 |
T2713 |
T2710 |
conj |
3,2 |
R1443 |
T2714 |
T2710 |
prep |
in,2 |
R1444 |
T2715 |
T2716 |
compound |
Figure,3A |
R1445 |
T2716 |
T2714 |
pobj |
3A,in |
R1446 |
T2717 |
T2716 |
cc |
and,3A |
R1447 |
T2718 |
T2719 |
compound |
Figure,3B |
R1448 |
T2719 |
T2716 |
conj |
3B,3A |
R1449 |
T2720 |
T2710 |
punct |
),2 |
R1450 |
T2721 |
T2702 |
punct |
.,exhibited |
R1451 |
T2723 |
T2724 |
det |
These,observations |
R1452 |
T2724 |
T2725 |
nsubj |
observations,indicate |
R1453 |
T2726 |
T2727 |
mark |
that,is |
R1454 |
T2727 |
T2725 |
ccomp |
is,indicate |
R1455 |
T2728 |
T2727 |
prep |
in,is |
R1456 |
T2729 |
T2728 |
pobj |
addition,in |
R1457 |
T2730 |
T2729 |
prep |
to,addition |
R1458 |
T2731 |
T2732 |
amod |
inner,segment |
R1459 |
T2732 |
T2733 |
compound |
segment,formation |
R1460 |
T2733 |
T2730 |
pobj |
formation,to |
R1461 |
T2734 |
T2727 |
punct |
", ",is |
R1462 |
T2735 |
T2727 |
nsubj |
ciliogenesis,is |
R1463 |
T2736 |
T2727 |
advmod |
also,is |
R1464 |
T2737 |
T2738 |
advmod |
largely,intact |
R1465 |
T2738 |
T2727 |
acomp |
intact,is |
R1466 |
T2739 |
T2727 |
prep |
in,is |
R1467 |
T2740 |
T2741 |
nmod |
Crx,photoreceptors |
R1469 |
T2742 |
T2740 |
punct |
-,Crx |
R1470 |
T2743 |
T2740 |
punct |
/,Crx |
R1542 |
T2848 |
T2849 |
punct |
(,mx |
R1543 |
T2849 |
T2837 |
parataxis |
mx,noted |
R1544 |
T2850 |
T2851 |
compound |
Figure,3A |
R1545 |
T2851 |
T2849 |
dep |
3A,mx |
R1546 |
T2852 |
T2849 |
punct |
", ",mx |
R1547 |
T2853 |
T2849 |
punct |
),mx |
R1548 |
T2854 |
T2837 |
punct |
.,noted |
R1549 |
T2856 |
T2857 |
advmod |
Second,found |
R1550 |
T2858 |
T2857 |
punct |
", ",found |
R1551 |
T2859 |
T2860 |
advmod |
sporadically,displaced |
R1552 |
T2860 |
T2861 |
amod |
displaced,nuclei |
R1553 |
T2861 |
T2857 |
nsubjpass |
nuclei,found |
R1554 |
T2862 |
T2857 |
auxpass |
were,found |
R1555 |
T2863 |
T2857 |
advcl |
residing,found |
R1556 |
T2864 |
T2863 |
prep |
in,residing |
R1557 |
T2865 |
T2866 |
det |
the,space |
R1558 |
T2866 |
T2864 |
pobj |
space,in |
R1559 |
T2867 |
T2866 |
acl |
abutting,space |
R1560 |
T2868 |
T2869 |
det |
the,PE |
R1561 |
T2869 |
T2867 |
dobj |
PE,abutting |
R1562 |
T2870 |
T2857 |
punct |
.,found |
R1563 |
T2872 |
T2873 |
advmod |
Occasionally,appeared |
R1564 |
T2874 |
T2873 |
punct |
", ",appeared |
R1565 |
T2875 |
T2876 |
det |
these,nuclei |
R1566 |
T2876 |
T2873 |
nsubj |
nuclei,appeared |
R1567 |
T2877 |
T2873 |
oprd |
pyknotic,appeared |
R1568 |
T2878 |
T2879 |
punct |
(,n |
R1569 |
T2879 |
T2873 |
parataxis |
n,appeared |
R1570 |
T2880 |
T2881 |
compound |
Figure,3A |
R1571 |
T2881 |
T2879 |
dep |
3A,n |
R1572 |
T2882 |
T2879 |
punct |
", ",n |
R1573 |
T2883 |
T2879 |
punct |
),n |
R1574 |
T2884 |
T2873 |
punct |
;,appeared |
R1575 |
T2885 |
T2873 |
cc |
but,appeared |
R1576 |
T2886 |
T2873 |
punct |
", ",appeared |
R1577 |
T2887 |
T2888 |
advmod |
more,frequently |
R1578 |
T2888 |
T2889 |
advmod |
frequently,exhibited |
R1579 |
T2889 |
T2873 |
conj |
exhibited,appeared |
R1580 |
T2890 |
T2891 |
det |
the,pattern |
R1581 |
T2891 |
T2889 |
dobj |
pattern,exhibited |
R1582 |
T2892 |
T2891 |
compound |
heterochromatin,pattern |
R1583 |
T2893 |
T2891 |
amod |
typical,pattern |
R1584 |
T2894 |
T2893 |
prep |
of,typical |
R1585 |
T2895 |
T2894 |
pobj |
photoreceptors,of |
R1586 |
T2896 |
T2897 |
punct |
(,shown |
R1587 |
T2897 |
T2889 |
parataxis |
shown,exhibited |
R1588 |
T2898 |
T2897 |
nsubj |
data,shown |
R1589 |
T2899 |
T2897 |
neg |
not,shown |
R1590 |
T2900 |
T2897 |
punct |
),shown |
R1591 |
T2901 |
T2889 |
punct |
", ",exhibited |
R1592 |
T2902 |
T2903 |
advmod |
strongly,suggesting |
R1593 |
T2903 |
T2889 |
advcl |
suggesting,exhibited |
R1594 |
T2904 |
T2905 |
mark |
that,belonged |
R1595 |
T2905 |
T2903 |
ccomp |
belonged,suggesting |
R1596 |
T2906 |
T2905 |
nsubj |
they,belonged |
R1597 |
T2907 |
T2905 |
prep |
to,belonged |
R1598 |
T2908 |
T2909 |
amod |
ectopic,photoreceptors |
R1599 |
T2909 |
T2907 |
pobj |
photoreceptors,to |
R1600 |
T2910 |
T2873 |
punct |
.,appeared |
R1601 |
T2912 |
T2913 |
det |
The,entity |
R1602 |
T2913 |
T2916 |
nsubj |
entity,were |
R1603 |
T2914 |
T2913 |
amod |
third,entity |
R1604 |
T2915 |
T2913 |
amod |
pathological,entity |
R1605 |
T2917 |
T2913 |
acl |
noted,entity |
R1606 |
T2918 |
T2917 |
prep |
in,noted |
R1607 |
T2919 |
T2920 |
det |
the,layer |
R1608 |
T2920 |
T2918 |
pobj |
layer,in |
R1609 |
T2921 |
T2922 |
amod |
outer,segment |
R1610 |
T2922 |
T2920 |
compound |
segment,layer |
R1611 |
T2923 |
T2924 |
amod |
numerous,vesicles |
R1612 |
T2924 |
T2916 |
attr |
vesicles,were |
R1613 |
T2925 |
T2924 |
amod |
small,vesicles |
R1614 |
T2926 |
T2927 |
punct |
(,arrow |
R1615 |
T2927 |
T2924 |
parataxis |
arrow,vesicles |
R1616 |
T2928 |
T2929 |
compound |
Figure,3A |
R1617 |
T2929 |
T2927 |
compound |
3A,arrow |
R1618 |
T2930 |
T2927 |
punct |
),arrow |
R1619 |
T2931 |
T2932 |
quantmod |
100,200 |
R1620 |
T2932 |
T2934 |
nummod |
200,nm |
R1621 |
T2933 |
T2932 |
quantmod |
to,200 |
R1622 |
T2934 |
T2924 |
appos |
nm,vesicles |
R1623 |
T2935 |
T2934 |
prep |
in,nm |
R1624 |
T2936 |
T2935 |
pobj |
diameter,in |
R1625 |
T2937 |
T2916 |
punct |
.,were |
R1626 |
T2939 |
T2940 |
nsubj |
They,appeared |
R1627 |
T2941 |
T2942 |
aux |
to,emerging |
R1628 |
T2942 |
T2940 |
xcomp |
emerging,appeared |
R1629 |
T2943 |
T2942 |
aux |
be,emerging |
R1630 |
T2944 |
T2942 |
prep |
from,emerging |
R1631 |
T2945 |
T2946 |
det |
the,segments |
R1632 |
T2946 |
T2944 |
pobj |
segments,from |
R1633 |
T2947 |
T2946 |
amod |
inner,segments |
R1634 |
T2948 |
T2940 |
punct |
", ",appeared |
R1635 |
T2949 |
T2950 |
mark |
as,showed |
R1636 |
T2950 |
T2940 |
advcl |
showed,appeared |
R1637 |
T2951 |
T2952 |
amod |
scanning,electron |
R1638 |
T2952 |
T2953 |
npadvmod |
electron,microscopic |
R1639 |
T2953 |
T2954 |
amod |
microscopic,images |
R1640 |
T2954 |
T2950 |
nsubj |
images,showed |
R1641 |
T2955 |
T2956 |
amod |
spherical,structures |
R1642 |
T2956 |
T2950 |
dobj |
structures,showed |
R1643 |
T2957 |
T2956 |
acl |
budding,structures |
R1644 |
T2958 |
T2957 |
prep |
from,budding |
R1645 |
T2959 |
T2960 |
det |
the,segments |
R1646 |
T2960 |
T2958 |
pobj |
segments,from |
R1647 |
T2961 |
T2960 |
amod |
inner,segments |
R1648 |
T2962 |
T2963 |
punct |
(,arrow |
R1649 |
T2963 |
T2950 |
parataxis |
arrow,showed |
R1650 |
T2964 |
T2965 |
compound |
Figure,3C |
R1651 |
T2965 |
T2963 |
dep |
3C,arrow |
R1652 |
T2966 |
T2963 |
punct |
", ",arrow |
R1653 |
T2967 |
T2963 |
punct |
),arrow |
R1654 |
T2968 |
T2940 |
punct |
.,appeared |
R1655 |
T2970 |
T2971 |
prep |
In,viewed |
R1656 |
T2972 |
T2970 |
pobj |
order,In |
R1657 |
T2973 |
T2974 |
aux |
to,characterize |
R1658 |
T2974 |
T2972 |
acl |
characterize,order |
R1659 |
T2975 |
T2974 |
advmod |
further,characterize |
R1660 |
T2976 |
T2977 |
det |
the,morphogenesis |
R1661 |
T2977 |
T2974 |
dobj |
morphogenesis,characterize |
R1662 |
T2978 |
T2977 |
prep |
of,morphogenesis |
R1663 |
T2979 |
T2980 |
nmod |
Crx,photoreceptors |
R1664 |
T2980 |
T2978 |
pobj |
photoreceptors,of |
R1665 |
T2981 |
T2979 |
punct |
-,Crx |
R1666 |
T2982 |
T2979 |
punct |
/,Crx |
R1667 |
T2983 |
T2979 |
punct |
-,Crx |
R1668 |
T2984 |
T2971 |
punct |
", ",viewed |
R1669 |
T2985 |
T2986 |
det |
the,layer |
R1670 |
T2986 |
T2971 |
nsubjpass |
layer,viewed |
R1671 |
T2987 |
T2986 |
amod |
developing,layer |
R1672 |
T2988 |
T2989 |
amod |
outer,segment |
R1673 |
T2989 |
T2986 |
compound |
segment,layer |
R1674 |
T2990 |
T2971 |
auxpass |
was,viewed |
R1675 |
T2991 |
T2971 |
prep |
by,viewed |
R1676 |
T2992 |
T2993 |
amod |
scanning,microscopy |
R1677 |
T2993 |
T2991 |
pobj |
microscopy,by |
R1678 |
T2994 |
T2993 |
compound |
electron,microscopy |
R1679 |
T2995 |
T2971 |
prep |
at,viewed |
R1680 |
T2996 |
T2995 |
pobj |
P7,at |
R1681 |
T2997 |
T2996 |
punct |
", ",P7 |
R1682 |
T2998 |
T2996 |
conj |
P14,P7 |
R1683 |
T2999 |
T2998 |
cc |
and,P14 |
R1684 |
T3000 |
T2998 |
conj |
P21,P14 |
R1685 |
T3001 |
T3002 |
punct |
(,Figure |
R1686 |
T3002 |
T2971 |
parataxis |
Figure,viewed |
R1687 |
T3003 |
T3002 |
nummod |
4,Figure |
R1688 |
T3004 |
T3002 |
punct |
),Figure |
R1689 |
T3005 |
T2971 |
punct |
.,viewed |
R1690 |
T3007 |
T3008 |
prep |
In,noted |
R1691 |
T3009 |
T3010 |
nmod |
Crx,retinas |
R1692 |
T3010 |
T3007 |
pobj |
retinas,In |
R1693 |
T3011 |
T3009 |
punct |
+,Crx |
R1694 |
T3012 |
T3009 |
punct |
/,Crx |
R1695 |
T3013 |
T3009 |
punct |
+,Crx |
R1696 |
T3014 |
T3008 |
punct |
", ",noted |
R1697 |
T3015 |
T3016 |
nmod |
photoreceptor,segments |
R1698 |
T3016 |
T3008 |
nsubjpass |
segments,noted |
R1699 |
T3017 |
T3016 |
amod |
inner,segments |
R1700 |
T3018 |
T3016 |
punct |
", ",segments |
R1701 |
T3019 |
T3020 |
amod |
connecting,cilia |
R1702 |
T3020 |
T3016 |
conj |
cilia,segments |
R1703 |
T3021 |
T3020 |
punct |
", ",cilia |
R1704 |
T3022 |
T3020 |
cc |
and,cilia |
R1705 |
T3023 |
T3024 |
det |
the,structures |
R1706 |
T3024 |
T3020 |
conj |
structures,cilia |
R1707 |
T3025 |
T3024 |
amod |
first,structures |
R1708 |
T3026 |
T3024 |
amod |
rudimentary,structures |
R1709 |
T3027 |
T3028 |
amod |
outer,segment |
R1710 |
T3028 |
T3024 |
compound |
segment,structures |
R1711 |
T3029 |
T3008 |
auxpass |
were,noted |
R1712 |
T3030 |
T3008 |
prep |
at,noted |
R1713 |
T3031 |
T3030 |
pobj |
P7,at |
R1714 |
T3032 |
T3008 |
punct |
.,noted |
R1715 |
T3034 |
T3035 |
prep |
In,emerging |
R1716 |
T3036 |
T3037 |
det |
the,retina |
R1717 |
T3037 |
T3034 |
pobj |
retina,In |
R1718 |
T3038 |
T3037 |
nmod |
Crx,retina |
R1719 |
T3039 |
T3038 |
punct |
-,Crx |
R1720 |
T3040 |
T3038 |
punct |
/,Crx |
R1721 |
T3041 |
T3038 |
punct |
-,Crx |
R1722 |
T3042 |
T3035 |
punct |
", ",emerging |
R1723 |
T3043 |
T3044 |
advmod |
only,cilium |
R1724 |
T3044 |
T3035 |
nsubjpass |
cilium,emerging |
R1725 |
T3045 |
T3044 |
det |
an,cilium |
R1726 |
T3046 |
T3044 |
amod |
occassional,cilium |
R1727 |
T3047 |
T3044 |
amod |
connecting,cilium |
R1728 |
T3048 |
T3035 |
auxpass |
was,emerging |
R1729 |
T3049 |
T3035 |
aux |
noted,emerging |
R1730 |
T3050 |
T3035 |
prep |
from,emerging |
R1731 |
T3051 |
T3052 |
amod |
inner,segments |
R1732 |
T3052 |
T3050 |
pobj |
segments,from |
R1733 |
T3053 |
T3035 |
prep |
at,emerging |
R1734 |
T3054 |
T3055 |
det |
this,stage |
R1735 |
T3055 |
T3053 |
pobj |
stage,at |
R1736 |
T3056 |
T3057 |
punct |
(,4A |
R1737 |
T3057 |
T3035 |
parataxis |
4A,emerging |
R1738 |
T3058 |
T3057 |
compound |
Figure,4A |
R1739 |
T3059 |
T3057 |
cc |
and,4A |
R1740 |
T3060 |
T3057 |
conj |
4B,4A |
R1741 |
T3061 |
T3057 |
punct |
),4A |
R1742 |
T3062 |
T3035 |
punct |
.,emerging |
R1743 |
T3064 |
T3065 |
det |
This,observation |
R1744 |
T3065 |
T3066 |
nsubjpass |
observation,confirmed |
R1745 |
T3067 |
T3066 |
auxpass |
was,confirmed |
R1746 |
T3068 |
T3066 |
prep |
by,confirmed |
R1747 |
T3069 |
T3068 |
pobj |
comparison,by |
R1748 |
T3070 |
T3069 |
prep |
with,comparison |
R1749 |
T3071 |
T3072 |
compound |
transmission,micrographs |
R1750 |
T3072 |
T3070 |
pobj |
micrographs,with |
R1751 |
T3073 |
T3072 |
compound |
electron,micrographs |
R1752 |
T3074 |
T3075 |
punct |
(,Figure |
R1753 |
T3075 |
T3066 |
parataxis |
Figure,confirmed |
R1754 |
T3076 |
T3075 |
nummod |
5,Figure |
R1755 |
T3077 |
T3075 |
punct |
),Figure |
R1756 |
T3078 |
T3066 |
punct |
.,confirmed |
R1757 |
T3080 |
T3081 |
det |
These,differences |
R1758 |
T3081 |
T3082 |
nsubj |
differences,are |
R1759 |
T3083 |
T3084 |
det |
the,differences |
R1760 |
T3084 |
T3082 |
attr |
differences,are |
R1761 |
T3085 |
T3084 |
amod |
earliest,differences |
R1762 |
T3086 |
T3084 |
amod |
noted,differences |
R1763 |
T3087 |
T3084 |
prep |
between,differences |
R1764 |
T3088 |
T3089 |
nmod |
Crx,photoreceptors |
R1765 |
T3089 |
T3087 |
pobj |
photoreceptors,between |
R1766 |
T3090 |
T3088 |
punct |
+,Crx |
R1767 |
T3091 |
T3088 |
punct |
/,Crx |
R1768 |
T3092 |
T3088 |
punct |
+,Crx |
R1769 |
T3093 |
T3088 |
cc |
and,Crx |
R1770 |
T3094 |
T3088 |
conj |
Crx,Crx |
R1771 |
T3095 |
T3094 |
punct |
-,Crx |
R1772 |
T3096 |
T3094 |
punct |
/,Crx |
R1773 |
T3097 |
T3094 |
punct |
-,Crx |
R1774 |
T3098 |
T3082 |
punct |
.,are |
R1775 |
T3100 |
T3101 |
prep |
At,noted |
R1776 |
T3102 |
T3100 |
pobj |
P14,At |
R1777 |
T3103 |
T3101 |
punct |
", ",noted |
R1778 |
T3104 |
T3105 |
amod |
elongating,segments |
R1779 |
T3105 |
T3101 |
nsubjpass |
segments,noted |
R1780 |
T3106 |
T3105 |
amod |
outer,segments |
R1781 |
T3107 |
T3101 |
auxpass |
were,noted |
R1782 |
T3108 |
T3101 |
prep |
on,noted |
R1783 |
T3109 |
T3110 |
nmod |
Crx,photoreceptors |
R1784 |
T3110 |
T3108 |
pobj |
photoreceptors,on |
R1785 |
T3111 |
T3109 |
punct |
+,Crx |
R1786 |
T3112 |
T3109 |
punct |
/,Crx |
R1787 |
T3113 |
T3109 |
punct |
+,Crx |
R1788 |
T3114 |
T3101 |
punct |
", ",noted |
R1789 |
T3115 |
T3116 |
advmod |
occasionally,demonstrating |
R1790 |
T3116 |
T3101 |
advcl |
demonstrating,noted |
R1791 |
T3117 |
T3118 |
det |
a,structure |
R1792 |
T3118 |
T3116 |
dobj |
structure,demonstrating |
R1793 |
T3119 |
T3120 |
npadvmod |
paddle,like |
R1794 |
T3120 |
T3118 |
amod |
like,structure |
R1795 |
T3121 |
T3120 |
punct |
-,like |
R1796 |
T3122 |
T3116 |
prep |
at,demonstrating |
R1797 |
T3123 |
T3124 |
poss |
their,apex |
R1798 |
T3124 |
T3122 |
pobj |
apex,at |
R1799 |
T3125 |
T3126 |
punct |
(,os |
R1800 |
T3126 |
T3116 |
parataxis |
os,demonstrating |
R1801 |
T3127 |
T3128 |
compound |
Figure,4C |
R1802 |
T3128 |
T3126 |
dep |
4C,os |
R1803 |
T3129 |
T3126 |
punct |
", ",os |
R1804 |
T3130 |
T3126 |
punct |
),os |
R1805 |
T3131 |
T3101 |
punct |
.,noted |
R1806 |
T3133 |
T3134 |
prep |
In,demonstrated |
R1807 |
T3135 |
T3136 |
nmod |
Crx,retinae |
R1808 |
T3136 |
T3133 |
pobj |
retinae,In |
R1809 |
T3137 |
T3135 |
punct |
-,Crx |
R1810 |
T3138 |
T3135 |
punct |
/,Crx |
R1811 |
T3139 |
T3135 |
punct |
-,Crx |
R1812 |
T3140 |
T3134 |
punct |
", ",demonstrated |
R1813 |
T3141 |
T3142 |
det |
the,majority |
R1814 |
T3142 |
T3134 |
nsubj |
majority,demonstrated |
R1815 |
T3143 |
T3142 |
amod |
vast,majority |
R1816 |
T3144 |
T3142 |
prep |
of,majority |
R1817 |
T3145 |
T3144 |
pobj |
photoreceptors,of |
R1818 |
T3153 |
T3151 |
pobj |
segments,without |
R1819 |
T3146 |
T3145 |
prep |
at,photoreceptors |
R1820 |
T3154 |
T3155 |
punct |
(,cc |
R1821 |
T3147 |
T3148 |
det |
this,stage |
R1822 |
T3155 |
T3134 |
parataxis |
cc,demonstrated |
R1823 |
T3156 |
T3157 |
compound |
Figure,4D |
R1824 |
T3148 |
T3146 |
pobj |
stage,at |
R1825 |
T3157 |
T3155 |
dep |
4D,cc |
R1826 |
T3158 |
T3155 |
punct |
", ",cc |
R1827 |
T3149 |
T3150 |
amod |
connecting,cilia |
R1828 |
T3159 |
T3155 |
punct |
),cc |
R1829 |
T3160 |
T3134 |
punct |
.,demonstrated |
R1830 |
T3150 |
T3134 |
dobj |
cilia,demonstrated |
R1831 |
T3162 |
T3163 |
advmod |
Sporadically,exhibit |
R1832 |
T3151 |
T3150 |
prep |
without,cilia |
R1833 |
T3164 |
T3163 |
punct |
", ",exhibit |
R1834 |
T3165 |
T3166 |
nmod |
Crx,photoreceptors |
R1835 |
T3166 |
T3163 |
nsubj |
photoreceptors,exhibit |
R1836 |
T3152 |
T3153 |
amod |
outer,segments |
R1837 |
T3167 |
T3165 |
punct |
-,Crx |
R1838 |
T3168 |
T3165 |
punct |
/,Crx |
R1839 |
T3258 |
T3259 |
compound |
Figure,4F |
R1840 |
T3169 |
T3165 |
punct |
-,Crx |
R1841 |
T3170 |
T3163 |
aux |
would,exhibit |
R1842 |
T3171 |
T3172 |
det |
an,structure |
R1843 |
T3259 |
T3257 |
dep |
4F,cc |
R1844 |
T3172 |
T3163 |
dobj |
structure,exhibit |
R1845 |
T3173 |
T3172 |
amod |
irregular,structure |
R1846 |
T3174 |
T3172 |
acl |
extending,structure |
R1847 |
T3260 |
T3257 |
punct |
", ",cc |
R1848 |
T3175 |
T3174 |
prep |
from,extending |
R1849 |
T3176 |
T3177 |
det |
a,cilium |
R1850 |
T3177 |
T3175 |
pobj |
cilium,from |
R1851 |
T3261 |
T3257 |
punct |
),cc |
R1852 |
T3178 |
T3177 |
amod |
connecting,cilium |
R1853 |
T3179 |
T3180 |
punct |
(,cc* |
R1854 |
T3262 |
T3242 |
punct |
.,noted |
R1855 |
T3180 |
T3174 |
parataxis |
cc*,extending |
R1856 |
T3181 |
T3182 |
compound |
Figure,4D |
R1857 |
T3182 |
T3180 |
dep |
4D,cc* |
R1858 |
T3183 |
T3180 |
punct |
", ",cc* |
R1859 |
T3264 |
T3265 |
amod |
Serial,examination |
R1860 |
T3184 |
T3180 |
punct |
),cc* |
R1861 |
T3185 |
T3186 |
advmod |
perhaps,representing |
R1862 |
T3186 |
T3172 |
acl |
representing,structure |
R1863 |
T3265 |
T3266 |
nsubj |
examination,demonstrated |
R1864 |
T3187 |
T3188 |
det |
a,segment |
R1865 |
T3188 |
T3186 |
dobj |
segment,representing |
R1866 |
T3189 |
T3188 |
amod |
malformed,segment |
R1867 |
T3190 |
T3188 |
amod |
outer,segment |
R1868 |
T3191 |
T3163 |
punct |
.,exhibit |
R1869 |
T3267 |
T3265 |
prep |
of,examination |
R1870 |
T3193 |
T3194 |
amod |
Such,structures |
R1871 |
T3194 |
T3195 |
nsubjpass |
structures,observed |
R1872 |
T3196 |
T3195 |
auxpass |
were,observed |
R1873 |
T3197 |
T3195 |
dobj |
also,observed |
R1874 |
T3268 |
T3269 |
nmod |
Crx,photoreceptors |
R1875 |
T3198 |
T3195 |
prep |
at,observed |
R1876 |
T3199 |
T3198 |
pobj |
P21,at |
R1877 |
T3269 |
T3267 |
pobj |
photoreceptors,of |
R1878 |
T3200 |
T3201 |
punct |
(,cc* |
R1879 |
T3201 |
T3195 |
parataxis |
cc*,observed |
R1880 |
T3202 |
T3203 |
compound |
Figure,4F |
R1881 |
T3270 |
T3268 |
punct |
-,Crx |
R1882 |
T3203 |
T3201 |
dep |
4F,cc* |
R1883 |
T3204 |
T3201 |
punct |
", ",cc* |
R1884 |
T3205 |
T3201 |
punct |
),cc* |
R1885 |
T3271 |
T3268 |
punct |
/,Crx |
R1886 |
T3206 |
T3195 |
punct |
.,observed |
R1887 |
T3272 |
T3268 |
punct |
-,Crx |
R1888 |
T3208 |
T3209 |
det |
These,segments |
R1889 |
T3209 |
T3214 |
nsubjpass |
segments,noted |
R1890 |
T3210 |
T3209 |
amod |
putative,segments |
R1891 |
T3273 |
T3265 |
prep |
at,examination |
R1892 |
T3211 |
T3209 |
punct |
", ",segments |
R1893 |
T3212 |
T3209 |
amod |
abnormal,segments |
R1894 |
T3213 |
T3209 |
amod |
outer,segments |
R1895 |
T3274 |
T3273 |
pobj |
P7,at |
R1896 |
T3215 |
T3214 |
auxpass |
were,noted |
R1897 |
T3216 |
T3217 |
advmod |
only,rarely |
R1898 |
T3275 |
T3274 |
punct |
", ",P7 |
R1899 |
T3217 |
T3214 |
advmod |
rarely,noted |
R1900 |
T3276 |
T3274 |
conj |
P10,P7 |
R1901 |
T3277 |
T3276 |
punct |
", ",P10 |
R1902 |
T3218 |
T3214 |
prep |
in,noted |
R1903 |
T3219 |
T3218 |
pobj |
Crx,in |
R1904 |
T3278 |
T3276 |
conj |
P14,P10 |
R1905 |
T3220 |
T3219 |
punct |
+,Crx |
R1906 |
T3221 |
T3219 |
punct |
/,Crx |
R1907 |
T3222 |
T3219 |
punct |
+,Crx |
R1908 |
T3279 |
T3278 |
punct |
", ",P14 |
R1909 |
T3280 |
T3278 |
cc |
and,P14 |
R1910 |
T3223 |
T3214 |
prep |
at,noted |
R1911 |
T3224 |
T3223 |
pobj |
P14,at |
R1912 |
T3281 |
T3278 |
conj |
P21,P14 |
R1913 |
T3225 |
T3214 |
punct |
", ",noted |
R1914 |
T3226 |
T3214 |
cc |
and,noted |
R1915 |
T3282 |
T3265 |
prep |
by,examination |
R1916 |
T3227 |
T3214 |
conj |
never,noted |
R1917 |
T3228 |
T3227 |
prep |
at,never |
R1918 |
T3229 |
T3228 |
pobj |
P21,at |
R1919 |
T3230 |
T3231 |
punct |
(,cc |
R1920 |
T3231 |
T3227 |
parataxis |
cc,never |
R1921 |
T3283 |
T3282 |
pobj |
TEM,by |
R1922 |
T3232 |
T3233 |
compound |
Figure,4C |
R1923 |
T3233 |
T3231 |
dep |
4C,cc |
R1924 |
T3234 |
T3233 |
cc |
and,4C |
R1925 |
T3284 |
T3266 |
punct |
", ",demonstrated |
R1926 |
T3235 |
T3233 |
conj |
4E,4C |
R1927 |
T3236 |
T3231 |
punct |
", ",cc |
R1928 |
T3237 |
T3231 |
punct |
*,cc |
R1929 |
T3285 |
T3286 |
det |
a,lack |
R1930 |
T3238 |
T3231 |
punct |
),cc |
R1931 |
T3239 |
T3214 |
punct |
.,noted |
R1932 |
T3286 |
T3266 |
dobj |
lack,demonstrated |
R1933 |
T3241 |
T3242 |
advmod |
Further,noted |
R1934 |
T3243 |
T3242 |
punct |
", ",noted |
R1935 |
T3287 |
T3286 |
amod |
distinctive,lack |
R1936 |
T3244 |
T3242 |
prep |
in,noted |
R1937 |
T3245 |
T3246 |
nmod |
Crx,photoreceptors |
R1938 |
T3246 |
T3244 |
pobj |
photoreceptors,in |
R1939 |
T3288 |
T3286 |
prep |
of,lack |
R1940 |
T3247 |
T3245 |
punct |
-,Crx |
R1941 |
T3248 |
T3245 |
punct |
/,Crx |
R1942 |
T3249 |
T3245 |
punct |
-,Crx |
R1943 |
T3289 |
T3290 |
det |
any,structure |
R1944 |
T3250 |
T3242 |
punct |
", ",noted |
R1945 |
T3251 |
T3252 |
advmod |
unusually,long |
R1946 |
T3290 |
T3288 |
pobj |
structure,of |
R1947 |
T3252 |
T3253 |
amod |
long,cilia |
R1948 |
T3253 |
T3242 |
nsubjpass |
cilia,noted |
R1949 |
T3254 |
T3253 |
amod |
connecting,cilia |
R1950 |
T3291 |
T3290 |
amod |
interpretable,structure |
R1951 |
T3255 |
T3242 |
auxpass |
were,noted |
R1952 |
T3256 |
T3257 |
punct |
(,cc |
R1953 |
T3257 |
T3242 |
parataxis |
cc,noted |
R1954 |
T3292 |
T3291 |
prep |
as,interpretable |
R1955 |
T3293 |
T3294 |
amod |
orderly,stacks |
R1956 |
T3294 |
T3292 |
pobj |
stacks,as |
R1957 |
T3295 |
T3294 |
prep |
of,stacks |
R1958 |
T3296 |
T3295 |
pobj |
discs,of |
R1959 |
T3297 |
T3296 |
cc |
or,discs |
R1960 |
T3298 |
T3299 |
amod |
forming,discs |
R1961 |
T3299 |
T3296 |
conj |
discs,discs |
R1962 |
T3300 |
T3266 |
punct |
.,demonstrated |
R1963 |
T3302 |
T3303 |
det |
These,data |
R1965 |
T3303 |
T3304 |
nsubj |
data,demonstrate |
R1966 |
T3305 |
T3306 |
det |
a,absence |
R1967 |
T3306 |
T3304 |
dobj |
absence,demonstrate |
R1968 |
T3307 |
T3306 |
amod |
complete,absence |
R1969 |
T3308 |
T3306 |
prep |
of,absence |
R1970 |
T3309 |
T3310 |
amod |
normal,formation |
R1988 |
T3377 |
T3375 |
pobj |
photoreceptors,to |
R1990 |
T3378 |
T3376 |
punct |
-,rhodopsin |
R1991 |
T3379 |
T3376 |
punct |
/,rhodopsin |
R1992 |
T3380 |
T3376 |
punct |
-,rhodopsin |
R1994 |
T3381 |
T3376 |
cc |
and,rhodopsin |
R1995 |
T3382 |
T3376 |
conj |
peripherin,rhodopsin |
R1996 |
T3383 |
T3382 |
punct |
-,peripherin |
R1998 |
T3384 |
T3382 |
punct |
/,peripherin |
R1999 |
T3385 |
T3382 |
punct |
-,peripherin |
R2000 |
T3386 |
T3365 |
punct |
.,compared |
R2005 |
T3388 |
T3389 |
nsubj |
Rhodopsin,are |
R2006 |
T3390 |
T3388 |
cc |
and,Rhodopsin |
R2008 |
T3391 |
T3388 |
conj |
peripherin,Rhodopsin |
R2009 |
T3392 |
T3393 |
nummod |
two,genes |
R2011 |
T3393 |
T3389 |
attr |
genes,are |
R2012 |
T3394 |
T3395 |
npadvmod |
photoreceptor,specific |
R2013 |
T3395 |
T3393 |
amod |
specific,genes |
R2015 |
T3396 |
T3395 |
punct |
-,specific |
R2016 |
T3397 |
T3398 |
poss |
whose,expression |
R2017 |
T3398 |
T3399 |
dep |
expression,downregulated |
R2019 |
T3399 |
T3393 |
relcl |
downregulated,genes |
R2020 |
T3400 |
T3399 |
auxpass |
is,downregulated |
R2021 |
T3401 |
T3399 |
advmod |
significantly,downregulated |
R2023 |
T3402 |
T3399 |
prep |
in,downregulated |
R2024 |
T3403 |
T3404 |
det |
the,retinae |
R2025 |
T3404 |
T3402 |
pobj |
retinae,in |
R2026 |
T3405 |
T3404 |
nmod |
Crx,retinae |
R2027 |
T3406 |
T3405 |
punct |
-,Crx |
R2029 |
T3407 |
T3405 |
punct |
/,Crx |
R2030 |
T3408 |
T3405 |
punct |
-,Crx |
R2031 |
T3409 |
T3410 |
punct |
[,35 |
R2032 |
T3410 |
T3399 |
parataxis |
35,downregulated |
R2034 |
T3411 |
T3410 |
nummod |
10,35 |
R2035 |
T3412 |
T3410 |
punct |
",",35 |
R2037 |
T3413 |
T3410 |
nummod |
34,35 |
R2038 |
T3414 |
T3410 |
punct |
",",35 |
R2039 |
T3415 |
T3410 |
punct |
],35 |
R2041 |
T3416 |
T3389 |
punct |
.,are |
R2043 |
T3418 |
T3419 |
nmod |
Loss,mutations |
R2044 |
T3419 |
T3422 |
nsubjpass |
mutations,reported |
R2045 |
T3420 |
T3418 |
prep |
of,Loss |
R2047 |
T3421 |
T3420 |
pobj |
function,of |
R2048 |
T3423 |
T3419 |
prep |
in,mutations |
R2050 |
T3424 |
T3423 |
pobj |
each,in |
R2051 |
T3425 |
T3424 |
prep |
of,each |
R2052 |
T3426 |
T3427 |
det |
these,genes |
R2054 |
T3427 |
T3425 |
pobj |
genes,of |
R2055 |
T3428 |
T3422 |
advmod |
separately,reported |
R2056 |
T3429 |
T3422 |
aux |
have,reported |
R2057 |
T3430 |
T3422 |
auxpass |
been,reported |
R2058 |
T3431 |
T3432 |
aux |
to,result |
R2059 |
T3432 |
T3422 |
xcomp |
result,reported |
R2060 |
T3433 |
T3432 |
prep |
in,result |
R2061 |
T3434 |
T3435 |
det |
a,failure |
R2062 |
T3435 |
T3433 |
pobj |
failure,in |
R2063 |
T3436 |
T3437 |
aux |
to,elaborate |
R2064 |
T3437 |
T3435 |
acl |
elaborate,failure |
R2065 |
T3438 |
T3439 |
amod |
outer,segments |
R2066 |
T3439 |
T3437 |
dobj |
segments,elaborate |
R2067 |
T3440 |
T3441 |
punct |
[,30 |
R2068 |
T3441 |
T3422 |
parataxis |
30,reported |
R2069 |
T3442 |
T3441 |
nummod |
29,30 |
R2070 |
T3443 |
T3441 |
punct |
",",30 |
R2071 |
T3444 |
T3441 |
punct |
],30 |
R2072 |
T3445 |
T3422 |
punct |
.,reported |
R2073 |
T3447 |
T3448 |
nsubj |
Photoreceptors,appeared |
R2074 |
T3449 |
T3447 |
prep |
from,Photoreceptors |
R2075 |
T3450 |
T3451 |
det |
these,mice |
R2076 |
T3451 |
T3449 |
pobj |
mice,from |
R2077 |
T3452 |
T3451 |
nummod |
two,mice |
R2078 |
T3453 |
T3451 |
amod |
mutant,mice |
R2079 |
T3454 |
T3451 |
acl |
examined,mice |
R2080 |
T3455 |
T3454 |
prep |
by,examined |
R2081 |
T3456 |
T3455 |
pobj |
SEM,by |
R2082 |
T3457 |
T3454 |
prep |
from,examined |
R2083 |
T3458 |
T3459 |
det |
the,side |
R2084 |
T3459 |
T3457 |
pobj |
side,from |
R2085 |
T3460 |
T3459 |
amod |
scleral,side |
R2086 |
T3461 |
T3462 |
advmod |
highly,similar |
R2087 |
T3462 |
T3448 |
oprd |
similar,appeared |
R2088 |
T3463 |
T3462 |
prep |
to,similar |
R2089 |
T3464 |
T3465 |
nmod |
Crx,photoreceptors |
R2090 |
T3465 |
T3463 |
pobj |
photoreceptors,to |
R2091 |
T3466 |
T3464 |
punct |
-,Crx |
R2092 |
T3467 |
T3464 |
punct |
/,Crx |
R2093 |
T3468 |
T3464 |
punct |
-,Crx |
R2094 |
T3469 |
T3470 |
punct |
(,compare |
R2095 |
T3470 |
T3448 |
parataxis |
compare,appeared |
R2096 |
T3471 |
T3472 |
compound |
Figure,4F |
R2097 |
T3472 |
T3470 |
dobj |
4F,compare |
R2098 |
T3473 |
T3470 |
prep |
to,compare |
R2099 |
T3474 |
T3475 |
compound |
Figure,6A |
R2100 |
T3475 |
T3473 |
pobj |
6A,to |
R2101 |
T3476 |
T3475 |
cc |
and,6A |
R2102 |
T3477 |
T3475 |
conj |
6B,6A |
R2103 |
T3478 |
T3470 |
punct |
),compare |
R2104 |
T3479 |
T3448 |
punct |
.,appeared |
R2111 |
T3638 |
T3639 |
nsubj |
Crx,is |
R2112 |
T3640 |
T3639 |
acomp |
necessary,is |
R2113 |
T3641 |
T3640 |
prep |
for,necessary |
R2114 |
T3642 |
T3643 |
det |
the,formation |
R2115 |
T3643 |
T3641 |
pobj |
formation,for |
R2116 |
T3644 |
T3643 |
prep |
of,formation |
R2117 |
T3645 |
T3646 |
compound |
photoreceptor,terminals |
R2118 |
T3646 |
T3644 |
pobj |
terminals,of |
R2119 |
T3648 |
T3649 |
prep |
In,demonstrated |
R2120 |
T3650 |
T3651 |
det |
a,study |
R2121 |
T3651 |
T3648 |
pobj |
study,In |
R2122 |
T3652 |
T3651 |
amod |
previous,study |
R2123 |
T3653 |
T3649 |
punct |
", ",demonstrated |
R2124 |
T3654 |
T3649 |
nsubj |
we,demonstrated |
R2125 |
T3655 |
T3656 |
mark |
that,blocked |
R2126 |
T3656 |
T3649 |
ccomp |
blocked,demonstrated |
R2127 |
T3657 |
T3658 |
amod |
forced,expression |
R2128 |
T3658 |
T3656 |
nsubj |
expression,blocked |
R2129 |
T3659 |
T3658 |
prep |
of,expression |
R2130 |
T3660 |
T3661 |
det |
a,allele |
R2131 |
T3661 |
T3659 |
pobj |
allele,of |
R2132 |
T3662 |
T3663 |
amod |
dominant,negative |
R2133 |
T3663 |
T3661 |
amod |
negative,allele |
R2134 |
T3664 |
T3663 |
punct |
-,negative |
R2135 |
T3665 |
T3661 |
prep |
of,allele |
R2136 |
T3666 |
T3665 |
pobj |
Crx,of |
R2137 |
T3667 |
T3658 |
prep |
in,expression |
R2138 |
T3668 |
T3669 |
amod |
developing,rods |
R2139 |
T3669 |
T3667 |
pobj |
rods,in |
R2140 |
T3670 |
T3656 |
dobj |
formation,blocked |
R2141 |
T3671 |
T3670 |
prep |
of,formation |
R2142 |
T3672 |
T3673 |
det |
both,spherules |
R2143 |
T3673 |
T3671 |
pobj |
spherules,of |
R2144 |
T3674 |
T3673 |
compound |
rod,spherules |
R2145 |
T3675 |
T3656 |
prep |
in,blocked |
R2146 |
T3676 |
T3677 |
det |
the,layer |
R2147 |
T3677 |
T3675 |
pobj |
layer,in |
R2148 |
T3678 |
T3677 |
amod |
outer,layer |
R2149 |
T3679 |
T3677 |
compound |
plexiform,layer |
R2150 |
T3680 |
T3677 |
punct |
(,layer |
R2151 |
T3681 |
T3677 |
appos |
OPL,layer |
R2152 |
T3682 |
T3677 |
punct |
),layer |
R2153 |
T3683 |
T3677 |
cc |
and,layer |
R2154 |
T3684 |
T3685 |
amod |
outer,segments |
R2155 |
T3685 |
T3677 |
conj |
segments,layer |
R2156 |
T3686 |
T3687 |
punct |
[,7 |
R2157 |
T3687 |
T3649 |
parataxis |
7,demonstrated |
R2158 |
T3688 |
T3687 |
punct |
],7 |
R2159 |
T3689 |
T3649 |
punct |
.,demonstrated |
R2160 |
T3691 |
T3692 |
aux |
To,expand |
R2161 |
T3692 |
T3693 |
advcl |
expand,examined |
R2162 |
T3694 |
T3692 |
prep |
on,expand |
R2163 |
T3695 |
T3696 |
det |
these,studies |
R2164 |
T3696 |
T3694 |
pobj |
studies,on |
R2165 |
T3697 |
T3693 |
punct |
", ",examined |
R2166 |
T3698 |
T3699 |
det |
the,ultrastructure |
R2167 |
T3699 |
T3693 |
nsubjpass |
ultrastructure,examined |
R2168 |
T3700 |
T3699 |
prep |
of,ultrastructure |
R2169 |
T3701 |
T3702 |
compound |
photoreceptor,synapses |
R2170 |
T3702 |
T3700 |
pobj |
synapses,of |
R2171 |
T3703 |
T3693 |
auxpass |
was,examined |
R2172 |
T3704 |
T3693 |
prep |
in,examined |
R2173 |
T3705 |
T3706 |
nmod |
Crx,retinas |
R2174 |
T3706 |
T3704 |
pobj |
retinas,in |
R2175 |
T3707 |
T3705 |
punct |
-,Crx |
R2176 |
T3708 |
T3705 |
punct |
/,Crx |
R2177 |
T3709 |
T3705 |
punct |
-,Crx |
R2178 |
T3710 |
T3693 |
punct |
.,examined |
R2179 |
T3712 |
T3713 |
prep |
In,were |
R2180 |
T3714 |
T3715 |
nmod |
Crx,retinas |
R2181 |
T3715 |
T3712 |
pobj |
retinas,In |
R2182 |
T3716 |
T3714 |
punct |
+,Crx |
R2183 |
T3717 |
T3714 |
punct |
/,Crx |
R2184 |
T3718 |
T3714 |
punct |
+,Crx |
R2185 |
T3719 |
T3713 |
prep |
at,were |
R2186 |
T3720 |
T3719 |
pobj |
P21,at |
R2187 |
T3721 |
T3713 |
punct |
", ",were |
R2188 |
T3722 |
T3723 |
advmod |
newly,mature |
R2189 |
T3723 |
T3724 |
amod |
mature,spherules |
R2190 |
T3724 |
T3713 |
nsubj |
spherules,were |
R2191 |
T3725 |
T3724 |
compound |
rod,spherules |
R2192 |
T3726 |
T3713 |
acomp |
abundant,were |
R2193 |
T3727 |
T3728 |
punct |
(,7A |
R2194 |
T3728 |
T3713 |
parataxis |
7A,were |
R2195 |
T3729 |
T3728 |
compound |
Figure,7A |
R2196 |
T3730 |
T3728 |
punct |
),7A |
R2197 |
T3731 |
T3713 |
punct |
.,were |
R2198 |
T3733 |
T3734 |
det |
The,sperules |
R2199 |
T3734 |
T3735 |
nsubj |
sperules,were |
R2200 |
T3736 |
T3737 |
amod |
blunt,structures |
R2201 |
T3737 |
T3735 |
attr |
structures,were |
R2202 |
T3738 |
T3736 |
cc |
or,blunt |
R2203 |
T3739 |
T3740 |
npadvmod |
club,shaped |
R2204 |
T3740 |
T3736 |
conj |
shaped,blunt |
R2205 |
T3741 |
T3740 |
punct |
-,shaped |
R2206 |
T3742 |
T3737 |
prep |
with,structures |
R2207 |
T3743 |
T3744 |
det |
a,ribbon |
R2208 |
T3744 |
T3742 |
pobj |
ribbon,with |
R2209 |
T3745 |
T3744 |
amod |
single,ribbon |
R2210 |
T3746 |
T3744 |
acl |
associated,ribbon |
R2211 |
T3747 |
T3746 |
prep |
with,associated |
R2212 |
T3748 |
T3749 |
det |
a,synapse |
R2213 |
T3749 |
T3747 |
pobj |
synapse,with |
R2214 |
T3750 |
T3749 |
amod |
single,synapse |
R2215 |
T3751 |
T3749 |
amod |
invaginating,synapse |
R2216 |
T3752 |
T3753 |
punct |
(,8A |
R2217 |
T3753 |
T3735 |
parataxis |
8A,were |
R2218 |
T3754 |
T3755 |
compound |
Figure,7A |
R2219 |
T3755 |
T3753 |
dep |
7A,8A |
R2220 |
T3756 |
T3753 |
punct |
", ",8A |
R2221 |
T3757 |
T3758 |
nsubj |
arrow,indicates |
R2222 |
T3758 |
T3753 |
ccomp |
indicates,8A |
R2223 |
T3759 |
T3760 |
nummod |
one,example |
R2224 |
T3760 |
T3758 |
dobj |
example,indicates |
R2225 |
T3761 |
T3753 |
punct |
;,8A |
R2226 |
T3762 |
T3753 |
compound |
Figure,8A |
R2227 |
T3763 |
T3753 |
cc |
and,8A |
R2228 |
T3764 |
T3753 |
conj |
8B,8A |
R2229 |
T3765 |
T3753 |
punct |
),8A |
R2230 |
T3766 |
T3735 |
punct |
.,were |
R2231 |
T3768 |
T3769 |
nummod |
Two,processes |
R2232 |
T3769 |
T3770 |
nsubjpass |
processes,situated |
R2233 |
T3771 |
T3769 |
prep |
from,processes |
R2234 |
T3772 |
T3773 |
amod |
horizontal,cells |
R2235 |
T3773 |
T3771 |
pobj |
cells,from |
R2236 |
T3774 |
T3770 |
auxpass |
were,situated |
R2237 |
T3775 |
T3770 |
prep |
on,situated |
R2238 |
T3776 |
T3777 |
det |
either,side |
R2239 |
T3777 |
T3775 |
pobj |
side,on |
R2240 |
T3778 |
T3777 |
prep |
of,side |
R2241 |
T3779 |
T3780 |
det |
the,ridge |
R2242 |
T3780 |
T3778 |
pobj |
ridge,of |
R2243 |
T3781 |
T3780 |
amod |
synaptic,ridge |
R2244 |
T3782 |
T3783 |
punct |
(,8B |
R2245 |
T3783 |
T3770 |
parataxis |
8B,situated |
R2246 |
T3784 |
T3783 |
compound |
Figure,8B |
R2247 |
T3785 |
T3783 |
punct |
", ",8B |
R2248 |
T3786 |
T3783 |
advcl |
labelled,8B |
R2249 |
T3787 |
T3786 |
ccomp |
H,labelled |
R2250 |
T3788 |
T3783 |
punct |
),8B |
R2251 |
T3789 |
T3770 |
cc |
and,situated |
R2252 |
T3790 |
T3791 |
nummod |
one,dendrites |
R2253 |
T3791 |
T3794 |
nsubj |
dendrites,occupied |
R2254 |
T3792 |
T3790 |
cc |
or,one |
R2255 |
T3793 |
T3790 |
conj |
more,one |
R2256 |
T3794 |
T3770 |
conj |
occupied,situated |
R2257 |
T3795 |
T3791 |
prep |
of,dendrites |
R2258 |
T3796 |
T3797 |
nmod |
rod,cells |
R2259 |
T3797 |
T3795 |
pobj |
cells,of |
R2260 |
T3798 |
T3797 |
amod |
bipolar,cells |
R2261 |
T3799 |
T3800 |
det |
a,position |
R2262 |
T3800 |
T3794 |
dobj |
position,occupied |
R2263 |
T3801 |
T3800 |
amod |
central,position |
R2264 |
T3802 |
T3803 |
punct |
(,B |
R2265 |
T3803 |
T3794 |
parataxis |
B,occupied |
R2266 |
T3804 |
T3805 |
compound |
Figure,8B |
R2267 |
T3805 |
T3803 |
dep |
8B,B |
R2268 |
T3806 |
T3803 |
punct |
", ",B |
R2269 |
T3807 |
T3808 |
amod |
bipolar,labelled |
R2270 |
T3808 |
T3803 |
amod |
labelled,B |
R2271 |
T3809 |
T3794 |
punct |
),occupied |
R2272 |
T3810 |
T3794 |
punct |
.,occupied |
R2273 |
T3812 |
T3813 |
compound |
Cone,terminals |
R2274 |
T3813 |
T3814 |
nsubj |
terminals,are |
R2275 |
T3815 |
T3816 |
amod |
large,flat |
R2276 |
T3816 |
T3818 |
amod |
flat,pedicles |
R2277 |
T3817 |
T3816 |
punct |
", ",flat |
R2278 |
T3818 |
T3814 |
attr |
pedicles,are |
R2279 |
T3819 |
T3820 |
dep |
that,exhibit |
R2280 |
T3820 |
T3818 |
relcl |
exhibit,pedicles |
R2281 |
T3821 |
T3822 |
amod |
many,synapses |
R2282 |
T3822 |
T3820 |
dobj |
synapses,exhibit |
R2283 |
T3823 |
T3822 |
amod |
invaginating,synapses |
R2284 |
T3824 |
T3822 |
acl |
containing,synapses |
R2285 |
T3825 |
T3826 |
amod |
separate,sets |
R2286 |
T3826 |
T3824 |
dobj |
sets,containing |
R2287 |
T3827 |
T3826 |
prep |
of,sets |
R2288 |
T3828 |
T3829 |
amod |
horizontal,processes |
R2289 |
T3829 |
T3827 |
pobj |
processes,of |
R2290 |
T3830 |
T3828 |
cc |
and,horizontal |
R2291 |
T3831 |
T3828 |
conj |
bipolar,horizontal |
R2292 |
T3832 |
T3829 |
compound |
cell,processes |
R2293 |
T3833 |
T3814 |
punct |
.,are |
R2294 |
T3835 |
T3836 |
det |
Each,pedicle |
R2295 |
T3836 |
T3837 |
nsubj |
pedicle,contains |
R2296 |
T3838 |
T3839 |
amod |
numerous,ribbons |
R2297 |
T3839 |
T3837 |
dobj |
ribbons,contains |
R2298 |
T3840 |
T3837 |
punct |
.,contains |
R2299 |
T3842 |
T3843 |
det |
These,terminals |
R2300 |
T3843 |
T3844 |
nsubj |
terminals,were |
R2301 |
T3845 |
T3846 |
advmod |
much,less |
R2302 |
T3846 |
T3847 |
advmod |
less,common |
R2303 |
T3847 |
T3844 |
acomp |
common,were |
R2304 |
T3848 |
T3847 |
prep |
than,common |
R2305 |
T3849 |
T3848 |
pobj |
spherules,than |
R2306 |
T3850 |
T3849 |
prep |
in,spherules |
R2307 |
T3851 |
T3852 |
nmod |
Crx,retinas |
R2308 |
T3852 |
T3850 |
pobj |
retinas,in |
R2309 |
T3853 |
T3851 |
punct |
+,Crx |
R2310 |
T3854 |
T3851 |
punct |
/,Crx |
R2311 |
T3855 |
T3851 |
punct |
+,Crx |
R2312 |
T3856 |
T3849 |
prep |
at,spherules |
R2313 |
T3857 |
T3856 |
pobj |
P21,at |
R2314 |
T3858 |
T3859 |
punct |
(,box |
R2315 |
T3859 |
T3844 |
parataxis |
box,were |
R2316 |
T3860 |
T3859 |
dep |
Figure,box |
R2317 |
T3861 |
T3860 |
nummod |
7,Figure |
R2318 |
T3862 |
T3859 |
punct |
", ",box |
R2319 |
T3863 |
T3859 |
punct |
),box |
R2320 |
T3864 |
T3844 |
punct |
.,were |
R2321 |
T3866 |
T3867 |
prep |
In,were |
R2322 |
T3868 |
T3869 |
det |
the,OPL |
R2323 |
T3869 |
T3866 |
pobj |
OPL,In |
R2324 |
T3870 |
T3869 |
prep |
of,OPL |
R2325 |
T3871 |
T3872 |
nmod |
Crx,retinas |
R2326 |
T3872 |
T3870 |
pobj |
retinas,of |
R2327 |
T3873 |
T3871 |
punct |
-,Crx |
R2328 |
T3874 |
T3871 |
punct |
/,Crx |
R2329 |
T3875 |
T3871 |
punct |
-,Crx |
R2330 |
T3876 |
T3867 |
punct |
", ",were |
R2331 |
T3877 |
T3878 |
compound |
photoreceptor,terminals |
R2332 |
T3878 |
T3867 |
nsubj |
terminals,were |
R2333 |
T3879 |
T3880 |
advmod |
highly,disorganized |
R2334 |
T3880 |
T3867 |
acomp |
disorganized,were |
R2335 |
T3881 |
T3867 |
prep |
at,were |
R2336 |
T3882 |
T3881 |
pobj |
P21,at |
R2337 |
T3883 |
T3884 |
punct |
(,arrows |
R2338 |
T3884 |
T3867 |
parataxis |
arrows,were |
R2339 |
T3885 |
T3886 |
compound |
Figure,7B |
R2340 |
T3886 |
T3884 |
dep |
7B,arrows |
R2341 |
T3887 |
T3884 |
punct |
", ",arrows |
R2342 |
T3888 |
T3884 |
punct |
),arrows |
R2343 |
T3889 |
T3867 |
punct |
.,were |
R2344 |
T3891 |
T3892 |
nsubj |
Processes,were |
R2345 |
T3893 |
T3891 |
acl |
containing,Processes |
R2346 |
T3894 |
T3895 |
amod |
synaptic,vesicles |
R2347 |
T3895 |
T3893 |
dobj |
vesicles,containing |
R2348 |
T3896 |
T3895 |
cc |
and,vesicles |
R2349 |
T3897 |
T3898 |
npadvmod |
ribbon,like |
R2350 |
T3898 |
T3900 |
amod |
like,structures |
R2351 |
T3899 |
T3898 |
punct |
-,like |
R2352 |
T3900 |
T3895 |
conj |
structures,vesicles |
R2353 |
T3901 |
T3892 |
acomp |
apparent,were |
R2354 |
T3902 |
T3892 |
punct |
", ",were |
R2355 |
T3903 |
T3892 |
advcl |
suggesting,were |
R2356 |
T3904 |
T3905 |
advmod |
at,least |
R2357 |
T3905 |
T3906 |
advmod |
least,limited |
R2358 |
T3906 |
T3907 |
amod |
limited,generation |
R2359 |
T3907 |
T3903 |
dobj |
generation,suggesting |
R2360 |
T3908 |
T3907 |
prep |
of,generation |
R2361 |
T3909 |
T3910 |
compound |
synapse,components |
R2362 |
T3910 |
T3908 |
pobj |
components,of |
R2363 |
T3911 |
T3892 |
punct |
.,were |
R2364 |
T3913 |
T3914 |
advmod |
However,observed |
R2365 |
T3915 |
T3914 |
punct |
", ",observed |
R2366 |
T3916 |
T3917 |
advmod |
well,formed |
R2367 |
T3917 |
T3918 |
amod |
formed,spherules |
R2368 |
T3918 |
T3914 |
nsubjpass |
spherules,observed |
R2369 |
T3919 |
T3918 |
cc |
and,spherules |
R2370 |
T3920 |
T3918 |
conj |
pedicles,spherules |
R2371 |
T3921 |
T3914 |
auxpass |
were,observed |
R2372 |
T3922 |
T3914 |
neg |
not,observed |
R2373 |
T3923 |
T3914 |
punct |
.,observed |
R2374 |
T3925 |
T3926 |
prep |
In,appeared |
R2375 |
T3927 |
T3925 |
pobj |
addition,In |
R2376 |
T3928 |
T3926 |
punct |
", ",appeared |
R2377 |
T3929 |
T3930 |
amod |
many,terminals |
R2378 |
T3930 |
T3926 |
nsubj |
terminals,appeared |
R2379 |
T3931 |
T3932 |
aux |
to,contain |
R2380 |
T3932 |
T3926 |
xcomp |
contain,appeared |
R2381 |
T3933 |
T3934 |
amod |
multiple,ribbons |
R2382 |
T3934 |
T3932 |
dobj |
ribbons,contain |
R2383 |
T3935 |
T3936 |
punct |
(,r |
R2384 |
T3936 |
T3934 |
parataxis |
r,ribbons |
R2385 |
T3937 |
T3938 |
compound |
Figure,8C |
R2386 |
T3938 |
T3936 |
dep |
8C,r |
R2387 |
T3939 |
T3938 |
cc |
and,8C |
R2388 |
T3940 |
T3938 |
conj |
8D,8C |
R2389 |
T3941 |
T3936 |
punct |
", ",r |
R2390 |
T3942 |
T3936 |
punct |
),r |
R2391 |
T3943 |
T3944 |
neg |
not,tethered |
R2392 |
T3944 |
T3934 |
acl |
tethered,ribbons |
R2393 |
T3945 |
T3944 |
prep |
to,tethered |
R2394 |
T3946 |
T3947 |
det |
the,membrane |
R2395 |
T3947 |
T3945 |
pobj |
membrane,to |
R2396 |
T3948 |
T3947 |
compound |
plasma,membrane |
R2397 |
T3949 |
T3944 |
cc |
and,tethered |
R2398 |
T3950 |
T3951 |
advmod |
occasionally,in |
R2399 |
T3951 |
T3944 |
conj |
in,tethered |
R2400 |
T3952 |
T3953 |
amod |
perinuclear,positions |
R2401 |
T3953 |
T3951 |
pobj |
positions,in |
R2402 |
T3954 |
T3955 |
punct |
(,8D |
R2403 |
T3955 |
T3932 |
parataxis |
8D,contain |
R2404 |
T3956 |
T3955 |
compound |
Figure,8D |
R2405 |
T3957 |
T3955 |
punct |
),8D |
R2406 |
T3958 |
T3926 |
punct |
.,appeared |
R5061 |
T8250 |
T8251 |
compound |
Transmission,microscopy |
R5062 |
T8252 |
T8251 |
compound |
electron,microscopy |
R5063 |
T8253 |
T8251 |
prep |
of,microscopy |
R5064 |
T8254 |
T8255 |
det |
the,retina |
R5065 |
T8255 |
T8253 |
pobj |
retina,of |
R5066 |
T8256 |
T8255 |
amod |
outer,retina |
R5067 |
T8257 |
T8251 |
prep |
at,microscopy |
R5068 |
T8258 |
T8257 |
pobj |
P21,at |
R5069 |
T8259 |
T8251 |
prep |
in,microscopy |
R5070 |
T8260 |
T8261 |
punct |
(,A |
R5071 |
T8261 |
T8262 |
meta |
A,Crx |
R5072 |
T8262 |
T8264 |
nmod |
Crx,retinas |
R5073 |
T8263 |
T8261 |
punct |
),A |
R5074 |
T8264 |
T8259 |
pobj |
retinas,in |
R5075 |
T8265 |
T8262 |
punct |
+,Crx |
R5076 |
T8266 |
T8262 |
punct |
/,Crx |
R5077 |
T8267 |
T8262 |
punct |
+,Crx |
R5078 |
T8268 |
T8262 |
cc |
and,Crx |
R5079 |
T8269 |
T8270 |
punct |
(,B |
R5080 |
T8270 |
T8271 |
meta |
B,Crx |
R5081 |
T8271 |
T8262 |
conj |
Crx,Crx |
R5082 |
T8272 |
T8270 |
punct |
),B |
R5083 |
T8273 |
T8271 |
punct |
-,Crx |
R5084 |
T8274 |
T8271 |
punct |
/,Crx |
R5085 |
T8275 |
T8271 |
punct |
-,Crx |
R5086 |
T8276 |
T8251 |
punct |
.,microscopy |
R5087 |
T8279 |
T8278 |
punct |
", ",pe |
R5088 |
T8280 |
T8281 |
amod |
pigmented,epithelium |
R5089 |
T8281 |
T8278 |
appos |
epithelium,pe |
R5090 |
T8282 |
T8278 |
punct |
.,pe |
R5091 |
T8285 |
T8284 |
punct |
", ",os |
R5092 |
T8286 |
T8287 |
amod |
outer,segments |
R5093 |
T8287 |
T8284 |
appos |
segments,os |
R5094 |
T8288 |
T8284 |
punct |
.,os |
R5095 |
T8291 |
T8290 |
punct |
", ",is |
R5096 |
T8292 |
T8293 |
amod |
inner,segments |
R5097 |
T8293 |
T8290 |
appos |
segments,is |
R5098 |
T8294 |
T8290 |
punct |
.,is |
R5099 |
T8297 |
T8296 |
punct |
", ",onl |
R5100 |
T8298 |
T8299 |
amod |
outer,layer |
R5101 |
T8299 |
T8296 |
appos |
layer,onl |
R5102 |
T8300 |
T8299 |
amod |
nuclear,layer |
R5103 |
T8301 |
T8299 |
prep |
with,layer |
R5104 |
T8302 |
T8303 |
compound |
photoreceptor,nuclei |
R5105 |
T8303 |
T8301 |
pobj |
nuclei,with |
R5106 |
T8304 |
T8296 |
punct |
.,onl |
R5107 |
T8306 |
T8307 |
compound |
Scale,bar |
R5108 |
T8307 |
T8308 |
nsubj |
bar,μm |
R5109 |
T8309 |
T8308 |
punct |
=,μm |
R5110 |
T8310 |
T8308 |
nummod |
5,μm |
R5111 |
T8311 |
T8308 |
prep |
for,μm |
R5112 |
T8312 |
T8311 |
pobj |
A,for |
R5113 |
T8313 |
T8312 |
cc |
and,A |
R5114 |
T8314 |
T8312 |
conj |
B,A |
R5115 |
T8315 |
T8308 |
punct |
.,μm |
R5118 |
T8372 |
T8373 |
compound |
Transmission,micrograph |
R5119 |
T8374 |
T8373 |
compound |
electron,micrograph |
R5120 |
T8375 |
T8373 |
prep |
of,micrograph |
R5121 |
T8376 |
T8377 |
det |
the,layer |
R5122 |
T8377 |
T8375 |
pobj |
layer,of |
R5123 |
T8378 |
T8379 |
amod |
outer,segment |
R5124 |
T8379 |
T8377 |
compound |
segment,layer |
R5125 |
T8380 |
T8377 |
prep |
of,layer |
R5126 |
T8381 |
T8382 |
nmod |
Crx,retina |
R5127 |
T8382 |
T8380 |
pobj |
retina,of |
R5128 |
T8383 |
T8381 |
punct |
-,Crx |
R5129 |
T8384 |
T8381 |
punct |
/,Crx |
R5130 |
T8385 |
T8381 |
punct |
-,Crx |
R5131 |
T8386 |
T8373 |
prep |
at,micrograph |
R5132 |
T8387 |
T8386 |
pobj |
P21,at |
R5133 |
T8388 |
T8373 |
punct |
.,micrograph |
R5134 |
T8390 |
T8391 |
amod |
Inner,segments |
R5135 |
T8391 |
T8392 |
nsubj |
segments,exhibit |
R5136 |
T8393 |
T8391 |
prep |
of,segments |
R5137 |
T8394 |
T8395 |
nmod |
Crx,photoreceptors |
R5138 |
T8395 |
T8393 |
pobj |
photoreceptors,of |
R5139 |
T8396 |
T8394 |
punct |
-,Crx |
R5140 |
T8397 |
T8394 |
punct |
/,Crx |
R5141 |
T8398 |
T8394 |
punct |
-,Crx |
R5142 |
T8399 |
T8400 |
amod |
numerous,mitochondria |
R5143 |
T8400 |
T8392 |
dobj |
mitochondria,exhibit |
R5144 |
T8401 |
T8402 |
punct |
(,indicated |
R5145 |
T8402 |
T8400 |
parataxis |
indicated,mitochondria |
R5146 |
T8403 |
T8402 |
nsubj |
m,indicated |
R5147 |
T8404 |
T8402 |
agent |
by,indicated |
R5148 |
T8405 |
T8404 |
pobj |
arrow,by |
R5149 |
T8406 |
T8402 |
punct |
),indicated |
R5150 |
T8407 |
T8392 |
prep |
as,exhibit |
R5151 |
T8408 |
T8407 |
prep |
in,as |
R5152 |
T8409 |
T8408 |
pobj |
Crx,in |
R5153 |
T8410 |
T8409 |
punct |
+,Crx |
R5154 |
T8411 |
T8409 |
punct |
/,Crx |
R5155 |
T8412 |
T8409 |
punct |
+,Crx |
R5156 |
T8413 |
T8414 |
punct |
(,Figure |
R5157 |
T8414 |
T8392 |
parataxis |
Figure,exhibit |
R5158 |
T8415 |
T8414 |
nummod |
1A,Figure |
R5159 |
T8416 |
T8414 |
punct |
),Figure |
R5160 |
T8417 |
T8392 |
punct |
.,exhibit |
R5161 |
T8420 |
T8419 |
punct |
", ",pe |
R5162 |
T8421 |
T8422 |
amod |
pigmented,epithelium |
R5163 |
T8422 |
T8419 |
appos |
epithelium,pe |
R5164 |
T8423 |
T8419 |
punct |
.,pe |
R5165 |
T8426 |
T8425 |
punct |
", ",is |
R5166 |
T8427 |
T8428 |
amod |
inner,segments |
R5167 |
T8428 |
T8425 |
appos |
segments,is |
R5168 |
T8429 |
T8425 |
punct |
.,is |
R5169 |
T8432 |
T8431 |
punct |
", ",onl |
R5170 |
T8433 |
T8434 |
amod |
outer,layer |
R5171 |
T8434 |
T8431 |
appos |
layer,onl |
R5172 |
T8435 |
T8434 |
amod |
nuclear,layer |
R5173 |
T8436 |
T8431 |
punct |
.,onl |
R5174 |
T8438 |
T8439 |
compound |
Scale,bar |
R5175 |
T8439 |
T8440 |
nsubj |
bar,μm |
R5176 |
T8441 |
T8440 |
punct |
=,μm |
R5177 |
T8442 |
T8440 |
nummod |
2,μm |
R5178 |
T8443 |
T8440 |
punct |
.,μm |
R5181 |
T8570 |
T8571 |
compound |
Transmission,micrograph |
R5182 |
T8572 |
T8571 |
compound |
electron,micrograph |
R5183 |
T8573 |
T8571 |
prep |
of,micrograph |
R5184 |
T8574 |
T8575 |
nmod |
Crx,retina |
R5185 |
T8575 |
T8573 |
pobj |
retina,of |
R5186 |
T8576 |
T8574 |
punct |
-,Crx |
R5187 |
T8577 |
T8574 |
punct |
/,Crx |
R5188 |
T8578 |
T8574 |
punct |
-,Crx |
R5189 |
T8579 |
T8575 |
prep |
at,retina |
R5190 |
T8580 |
T8579 |
pobj |
P21,at |
R5191 |
T8581 |
T8582 |
punct |
(,A |
R5192 |
T8582 |
T8571 |
parataxis |
A,micrograph |
R5193 |
T8583 |
T8582 |
cc |
and,A |
R5194 |
T8584 |
T8582 |
conj |
B,A |
R5195 |
T8585 |
T8582 |
punct |
),A |
R5196 |
T8586 |
T8571 |
punct |
", ",micrograph |
R5197 |
T8587 |
T8571 |
cc |
and,micrograph |
R5198 |
T8588 |
T8589 |
amod |
scanning,micrograph |
R5199 |
T8589 |
T8571 |
conj |
micrograph,micrograph |
R5200 |
T8590 |
T8589 |
compound |
electron,micrograph |
R5201 |
T8591 |
T8589 |
prep |
of,micrograph |
R5202 |
T8592 |
T8591 |
pobj |
Crx,of |
R5203 |
T8593 |
T8592 |
punct |
-,Crx |
R5204 |
T8594 |
T8592 |
punct |
/,Crx |
R5205 |
T8595 |
T8592 |
punct |
-,Crx |
R5206 |
T8596 |
T8592 |
prep |
at,Crx |
R5207 |
T8597 |
T8596 |
pobj |
P10,at |
R5208 |
T8598 |
T8599 |
punct |
(,C |
R5209 |
T8599 |
T8589 |
parataxis |
C,micrograph |
R5210 |
T8600 |
T8599 |
punct |
),C |
R5211 |
T8601 |
T8571 |
prep |
of,micrograph |
R5212 |
T8602 |
T8603 |
amod |
outer,segment |
R5213 |
T8603 |
T8604 |
compound |
segment,layer |
R5214 |
T8604 |
T8601 |
pobj |
layer,of |
R5215 |
T8605 |
T8571 |
punct |
.,micrograph |
R5216 |
T8607 |
T8608 |
punct |
(,A |
R5217 |
T8608 |
T8609 |
meta |
A,Evidence |
R5218 |
T8610 |
T8608 |
punct |
),A |
R5219 |
T8611 |
T8609 |
prep |
of,Evidence |
R5220 |
T8612 |
T8611 |
pobj |
ciliogenesis,of |
R5221 |
T8613 |
T8609 |
prep |
in,Evidence |
R5222 |
T8614 |
T8615 |
det |
the,layer |
R5223 |
T8615 |
T8613 |
pobj |
layer,in |
R5224 |
T8616 |
T8615 |
compound |
photoreceptor,layer |
R5225 |
T8617 |
T8615 |
prep |
of,layer |
R5226 |
T8618 |
T8619 |
nmod |
Crx,retina |
R5227 |
T8619 |
T8617 |
pobj |
retina,of |
R5228 |
T8620 |
T8618 |
punct |
-,Crx |
R5229 |
T8621 |
T8618 |
punct |
/,Crx |
R5230 |
T8622 |
T8618 |
punct |
-,Crx |
R5231 |
T8623 |
T8609 |
punct |
.,Evidence |
R5232 |
T8625 |
T8626 |
amod |
Nonmotile,cilia |
R5233 |
T8626 |
T8628 |
nsubjpass |
cilia,observed |
R5234 |
T8627 |
T8626 |
amod |
connecting,cilia |
R5235 |
T8629 |
T8628 |
auxpass |
were,observed |
R5236 |
T8630 |
T8628 |
prep |
in,observed |
R5237 |
T8631 |
T8632 |
compound |
cross,section |
R5238 |
T8632 |
T8630 |
pobj |
section,in |
R5239 |
T8633 |
T8634 |
punct |
(,1 |
R5240 |
T8634 |
T8628 |
parataxis |
1,observed |
R5241 |
T8635 |
T8634 |
nmod |
arrowheads,1 |
R5242 |
T8636 |
T8634 |
punct |
",",1 |
R5243 |
T8637 |
T8634 |
conj |
2,1 |
R5244 |
T8638 |
T8637 |
punct |
", ",2 |
R5245 |
T8639 |
T8637 |
cc |
and,2 |
R5246 |
T8640 |
T8637 |
conj |
3,2 |
R5247 |
T8641 |
T8634 |
punct |
", ",1 |
R5248 |
T8642 |
T8634 |
prep |
for,1 |
R5249 |
T8643 |
T8642 |
pobj |
examples,for |
R5250 |
T8644 |
T8634 |
punct |
),1 |
R5251 |
T8645 |
T8628 |
punct |
.,observed |
R5252 |
T8647 |
T8648 |
amod |
Connecting,cilium |
R5253 |
T8648 |
T8649 |
nsubj |
cilium,demonstrated |
R5254 |
T8650 |
T8648 |
nummod |
1,cilium |
R5255 |
T8651 |
T8652 |
punct |
(,arrowhead |
R5256 |
T8652 |
T8648 |
parataxis |
arrowhead,cilium |
R5257 |
T8653 |
T8652 |
nummod |
1,arrowhead |
R5258 |
T8654 |
T8652 |
punct |
),arrowhead |
R5259 |
T8655 |
T8656 |
nummod |
seven,doublets |
R5260 |
T8656 |
T8649 |
dobj |
doublets,demonstrated |
R5261 |
T8657 |
T8656 |
amod |
microtuble,doublets |
R5262 |
T8658 |
T8649 |
punct |
", ",demonstrated |
R5263 |
T8659 |
T8660 |
mark |
while,exhibited |
R5264 |
T8660 |
T8649 |
advcl |
exhibited,demonstrated |
R5265 |
T8661 |
T8660 |
nsubj |
cilium,exhibited |
R5266 |
T8662 |
T8661 |
nummod |
2,cilium |
R5267 |
T8663 |
T8661 |
cc |
and,cilium |
R5268 |
T8664 |
T8661 |
conj |
cilium,cilium |
R5269 |
T8665 |
T8664 |
nummod |
3,cilium |
R5270 |
T8666 |
T8660 |
dobj |
nine,exhibited |
R5271 |
T8667 |
T8649 |
punct |
.,demonstrated |
R5272 |
T8669 |
T8670 |
prep |
In,seen |
R5273 |
T8671 |
T8669 |
pobj |
A,In |
R5274 |
T8672 |
T8670 |
punct |
", ",seen |
R5275 |
T8673 |
T8674 |
det |
a,nucleus |
R5276 |
T8674 |
T8670 |
nsubjpass |
nucleus,seen |
R5277 |
T8675 |
T8674 |
amod |
displaced,nucleus |
R5278 |
T8676 |
T8674 |
compound |
cell,nucleus |
R5279 |
T8677 |
T8674 |
punct |
(,nucleus |
R5280 |
T8678 |
T8674 |
appos |
n,nucleus |
R5281 |
T8679 |
T8674 |
punct |
),nucleus |
R5282 |
T8680 |
T8674 |
acl |
appearing,nucleus |
R5283 |
T8681 |
T8680 |
oprd |
pyknotic,appearing |
R5284 |
T8682 |
T8674 |
cc |
and,nucleus |
R5285 |
T8683 |
T8684 |
amod |
abnormal,deposition |
R5286 |
T8684 |
T8674 |
conj |
deposition,nucleus |
R5287 |
T8685 |
T8684 |
prep |
of,deposition |
R5288 |
T8686 |
T8687 |
nmod |
matrix,material |
R5289 |
T8687 |
T8685 |
pobj |
material,of |
R5290 |
T8688 |
T8686 |
punct |
(,matrix |
R5291 |
T8689 |
T8686 |
appos |
mx,matrix |
R5292 |
T8690 |
T8687 |
punct |
),material |
R5293 |
T8691 |
T8687 |
prep |
of,material |
R5294 |
T8692 |
T8693 |
amod |
unknown,identity |
R5295 |
T8693 |
T8691 |
pobj |
identity,of |
R5296 |
T8694 |
T8670 |
auxpass |
were,seen |
R5297 |
T8695 |
T8670 |
punct |
", ",seen |
R5298 |
T8696 |
T8670 |
prep |
along,seen |
R5299 |
T8697 |
T8696 |
prep |
with,along |
R5300 |
T8698 |
T8699 |
amod |
large,amounts |
R5301 |
T8699 |
T8697 |
pobj |
amounts,with |
R5302 |
T8700 |
T8699 |
prep |
of,amounts |
R5303 |
T8701 |
T8702 |
amod |
membranous,vesicles |
R5304 |
T8702 |
T8700 |
pobj |
vesicles,of |
R5305 |
T8703 |
T8704 |
punct |
(,arrow |
R5306 |
T8704 |
T8702 |
parataxis |
arrow,vesicles |
R5307 |
T8705 |
T8704 |
punct |
),arrow |
R5308 |
T8706 |
T8707 |
dep |
which,filled |
R5309 |
T8707 |
T8699 |
relcl |
filled,amounts |
R5310 |
T8708 |
T8709 |
det |
the,space |
R5311 |
T8709 |
T8707 |
dobj |
space,filled |
R5312 |
T8710 |
T8709 |
compound |
photoreceptor,space |
R5313 |
T8711 |
T8707 |
cc |
and,filled |
R5314 |
T8712 |
T8707 |
conj |
appeared,filled |
R5315 |
T8713 |
T8714 |
aux |
to,released |
R5316 |
T8714 |
T8712 |
xcomp |
released,appeared |
R5317 |
T8715 |
T8714 |
auxpass |
be,released |
R5318 |
T8716 |
T8714 |
prep |
from,released |
R5319 |
T8717 |
T8718 |
amod |
inner,segments |
R5320 |
T8718 |
T8716 |
pobj |
segments,from |
R5321 |
T8719 |
T8670 |
punct |
.,seen |
R5322 |
T8721 |
T8722 |
compound |
Scale,bar |
R5323 |
T8722 |
T8723 |
nsubj |
bar,μm |
R5324 |
T8724 |
T8723 |
punct |
=,μm |
R5325 |
T8725 |
T8723 |
nummod |
3.7,μm |
R5326 |
T8726 |
T8723 |
punct |
.,μm |
R5327 |
T8728 |
T8729 |
punct |
(,B |
R5328 |
T8729 |
T8730 |
meta |
B,cilium |
R5329 |
T8731 |
T8729 |
punct |
),B |
R5330 |
T8732 |
T8730 |
amod |
Nonmotile,cilium |
R5331 |
T8733 |
T8730 |
amod |
connecting,cilium |
R5332 |
T8734 |
T8730 |
prep |
in,cilium |
R5333 |
T8735 |
T8736 |
compound |
cross,section |
R5334 |
T8736 |
T8734 |
pobj |
section,in |
R5335 |
T8737 |
T8730 |
punct |
", ",cilium |
R5336 |
T8738 |
T8730 |
prep |
from,cilium |
R5337 |
T8739 |
T8740 |
det |
a,photoreceptor |
R5338 |
T8740 |
T8738 |
pobj |
photoreceptor,from |
R5339 |
T8741 |
T8740 |
nmod |
Crx,photoreceptor |
R5340 |
T8742 |
T8741 |
punct |
-,Crx |
R5341 |
T8743 |
T8741 |
punct |
/,Crx |
R5342 |
T8744 |
T8741 |
punct |
-,Crx |
R5343 |
T8745 |
T8730 |
punct |
", ",cilium |
R5344 |
T8746 |
T8730 |
acl |
demonstrating,cilium |
R5345 |
T8747 |
T8748 |
amod |
characteristic,array |
R5346 |
T8748 |
T8746 |
dobj |
array,demonstrating |
R5347 |
T8749 |
T8750 |
nummod |
9,0 |
R5348 |
T8750 |
T8748 |
nummod |
0,array |
R5349 |
T8751 |
T8750 |
punct |
+,0 |
R5350 |
T8752 |
T8748 |
amod |
radial,array |
R5351 |
T8753 |
T8748 |
prep |
of,array |
R5352 |
T8754 |
T8755 |
compound |
microtubule,doublets |
R5353 |
T8755 |
T8753 |
pobj |
doublets,of |
R5354 |
T8756 |
T8730 |
punct |
.,cilium |
R5355 |
T8758 |
T8759 |
compound |
Scale,bar |
R5356 |
T8759 |
T8760 |
nsubj |
bar,nm |
R5357 |
T8761 |
T8760 |
punct |
=,nm |
R5358 |
T8762 |
T8760 |
nummod |
88,nm |
R5359 |
T8763 |
T8760 |
punct |
.,nm |
R5360 |
T8765 |
T8766 |
punct |
(,C |
R5361 |
T8766 |
T8767 |
meta |
C,micrograph |
R5362 |
T8768 |
T8766 |
punct |
),C |
R5363 |
T8769 |
T8767 |
amod |
Scanning,micrograph |
R5364 |
T8770 |
T8767 |
compound |
electron,micrograph |
R5365 |
T8771 |
T8772 |
punct |
(,SEM |
R5366 |
T8772 |
T8767 |
appos |
SEM,micrograph |
R5367 |
T8773 |
T8767 |
punct |
),micrograph |
R5368 |
T8774 |
T8767 |
prep |
of,micrograph |
R5369 |
T8775 |
T8776 |
amod |
membranous,vesicles |
R5370 |
T8776 |
T8774 |
pobj |
vesicles,of |
R5371 |
T8777 |
T8778 |
punct |
(,shows |
R5372 |
T8778 |
T8776 |
parataxis |
shows,vesicles |
R5373 |
T8779 |
T8778 |
nsubj |
arrow,shows |
R5374 |
T8780 |
T8781 |
nummod |
one,example |
R5375 |
T8781 |
T8778 |
dobj |
example,shows |
R5376 |
T8782 |
T8778 |
punct |
),shows |
R5377 |
T8783 |
T8776 |
acl |
shed,vesicles |
R5378 |
T8784 |
T8783 |
prep |
from,shed |
R5379 |
T8785 |
T8786 |
amod |
inner,segments |
R5380 |
T8786 |
T8784 |
pobj |
segments,from |
R5381 |
T8787 |
T8786 |
prep |
of,segments |
R5382 |
T8788 |
T8789 |
nmod |
Crx,photoreceptors |
R5383 |
T8789 |
T8787 |
pobj |
photoreceptors,of |
R5384 |
T8790 |
T8788 |
punct |
-,Crx |
R5385 |
T8791 |
T8788 |
punct |
/,Crx |
R5386 |
T8792 |
T8788 |
punct |
-,Crx |
R5387 |
T8793 |
T8783 |
prep |
at,shed |
R5388 |
T8794 |
T8793 |
pobj |
P10,at |
R5389 |
T8795 |
T8767 |
punct |
.,micrograph |
R5390 |
T8797 |
T8798 |
nsubj |
Figure,shows |
R5391 |
T8799 |
T8800 |
amod |
inner,segments |
R5392 |
T8800 |
T8798 |
dobj |
segments,shows |
R5393 |
T8801 |
T8800 |
acl |
viewed,segments |
R5394 |
T8802 |
T8801 |
prep |
from,viewed |
R5395 |
T8803 |
T8804 |
det |
the,side |
R5396 |
T8804 |
T8802 |
pobj |
side,from |
R5397 |
T8805 |
T8804 |
amod |
scleral,side |
R5398 |
T8806 |
T8807 |
mark |
with,removed |
R5399 |
T8807 |
T8798 |
advcl |
removed,shows |
R5400 |
T8808 |
T8809 |
det |
the,epithelium |
R5401 |
T8809 |
T8807 |
nsubj |
epithelium,removed |
R5402 |
T8810 |
T8809 |
amod |
pigmented,epithelium |
R5403 |
T8811 |
T8798 |
punct |
.,shows |
R5404 |
T8813 |
T8814 |
compound |
Scale,bar |
R5405 |
T8814 |
T8815 |
nsubj |
bar,μm |
R5406 |
T8816 |
T8815 |
punct |
=,μm |
R5407 |
T8817 |
T8815 |
nummod |
1,μm |
R5408 |
T8818 |
T8815 |
punct |
.,μm |
R5409 |
T8923 |
T8924 |
compound |
Outer,segment |
R5410 |
T8924 |
T8925 |
compound |
segment,morphogenesis |
R5411 |
T8926 |
T8925 |
prep |
in,morphogenesis |
R5412 |
T8927 |
T8928 |
nmod |
Crx,photoreceptors |
R5413 |
T8928 |
T8926 |
pobj |
photoreceptors,in |
R5414 |
T8929 |
T8927 |
punct |
-,Crx |
R5415 |
T8930 |
T8927 |
punct |
/,Crx |
R5416 |
T8931 |
T8927 |
punct |
-,Crx |
R5417 |
T8932 |
T8925 |
punct |
.,morphogenesis |
R5418 |
T8934 |
T8935 |
amod |
Scanning,microscopy |
R5419 |
T8936 |
T8935 |
compound |
electron,microscopy |
R5420 |
T8937 |
T8935 |
prep |
of,microscopy |
R5421 |
T8938 |
T8939 |
amod |
developing,photoreceptors |
R5422 |
T8939 |
T8937 |
pobj |
photoreceptors,of |
R5423 |
T8940 |
T8939 |
acl |
viewed,photoreceptors |
R5424 |
T8941 |
T8940 |
prep |
from,viewed |
R5425 |
T8942 |
T8943 |
det |
the,side |
R5426 |
T8943 |
T8941 |
pobj |
side,from |
R5427 |
T8944 |
T8943 |
amod |
scleral,side |
R5428 |
T8945 |
T8946 |
mark |
with,removed |
R5429 |
T8946 |
T8940 |
advcl |
removed,viewed |
R5430 |
T8947 |
T8948 |
det |
the,epithelium |
R5431 |
T8948 |
T8946 |
nsubj |
epithelium,removed |
R5432 |
T8949 |
T8948 |
amod |
pigmented,epithelium |
R5433 |
T8950 |
T8946 |
prep |
at,removed |
R5434 |
T8951 |
T8950 |
pobj |
P7,at |
R5435 |
T8952 |
T8951 |
punct |
", ",P7 |
R5436 |
T8953 |
T8951 |
conj |
P14,P7 |
R5437 |
T8954 |
T8953 |
punct |
", ",P14 |
R5438 |
T8955 |
T8953 |
cc |
and,P14 |
R5439 |
T8956 |
T8953 |
conj |
P21,P14 |
R5440 |
T8957 |
T8946 |
prep |
for,removed |
R5441 |
T8958 |
T8959 |
nmod |
Crx,littermates |
R5442 |
T8959 |
T8957 |
pobj |
littermates,for |
R5443 |
T8960 |
T8958 |
punct |
+,Crx |
R5444 |
T8961 |
T8958 |
punct |
/,Crx |
R5445 |
T8962 |
T8958 |
punct |
+,Crx |
R5446 |
T8963 |
T8964 |
punct |
(,A |
R5447 |
T8964 |
T8958 |
parataxis |
A,Crx |
R5448 |
T8965 |
T8964 |
punct |
", ",A |
R5449 |
T8966 |
T8964 |
conj |
C,A |
R5450 |
T8967 |
T8966 |
punct |
", ",C |
R5451 |
T8968 |
T8966 |
cc |
and,C |
R5452 |
T8969 |
T8966 |
conj |
E,C |
R5453 |
T8970 |
T8964 |
punct |
),A |
R5454 |
T8971 |
T8958 |
cc |
and,Crx |
R5455 |
T8972 |
T8958 |
conj |
Crx,Crx |
R5456 |
T8973 |
T8972 |
punct |
-,Crx |
R5457 |
T8974 |
T8972 |
punct |
/,Crx |
R5458 |
T8975 |
T8972 |
punct |
-,Crx |
R5459 |
T8976 |
T8977 |
punct |
(,F |
R5460 |
T8977 |
T8972 |
parataxis |
F,Crx |
R5461 |
T8978 |
T8977 |
nmod |
B,F |
R5462 |
T8979 |
T8977 |
punct |
", ",F |
R5463 |
T8980 |
T8977 |
nmod |
D,F |
R5464 |
T8981 |
T8977 |
punct |
", ",F |
R5465 |
T8982 |
T8977 |
punct |
),F |
R5466 |
T8983 |
T8935 |
punct |
.,microscopy |
R5467 |
T8985 |
T8986 |
prep |
In,were |
R5468 |
T8987 |
T8988 |
nmod |
Crx,retina |
R5469 |
T8988 |
T8985 |
pobj |
retina,In |
R5470 |
T8989 |
T8987 |
punct |
+,Crx |
R5471 |
T8990 |
T8987 |
punct |
/,Crx |
R5472 |
T8991 |
T8987 |
punct |
+,Crx |
R5473 |
T8992 |
T8986 |
punct |
", ",were |
R5474 |
T8993 |
T8994 |
amod |
numerous,cilia |
R5475 |
T8994 |
T8986 |
nsubj |
cilia,were |
R5476 |
T8995 |
T8994 |
amod |
connecting,cilia |
R5477 |
T8996 |
T8997 |
punct |
(,cc |
R5478 |
T8997 |
T8994 |
parataxis |
cc,cilia |
R5479 |
T8998 |
T8997 |
dep |
A,cc |
R5480 |
T8999 |
T8997 |
punct |
", ",cc |
R5481 |
T9000 |
T8997 |
punct |
),cc |
R5482 |
T9001 |
T8986 |
acomp |
evident,were |
R5483 |
T9002 |
T8986 |
prep |
at,were |
R5484 |
T9003 |
T9002 |
pobj |
P7,at |
R5485 |
T9004 |
T8986 |
prep |
with,were |
R5486 |
T9005 |
T9006 |
amod |
rudimentary,segments |
R5487 |
T9006 |
T9004 |
pobj |
segments,with |
R5488 |
T9007 |
T9006 |
amod |
outer,segments |
R5489 |
T9008 |
T8986 |
punct |
.,were |
R5490 |
T9010 |
T9011 |
prep |
After,occurs |
R5491 |
T9012 |
T9010 |
pobj |
P7,After |
R5492 |
T9013 |
T9011 |
punct |
", ",occurs |
R5493 |
T9014 |
T9011 |
prep |
in,occurs |
R5494 |
T9015 |
T9014 |
pobj |
Crx,in |
R5495 |
T9016 |
T9015 |
punct |
+,Crx |
R5496 |
T9017 |
T9015 |
punct |
/,Crx |
R5497 |
T9018 |
T9015 |
punct |
+,Crx |
R5498 |
T9019 |
T9020 |
amod |
outer,segment |
R5499 |
T9020 |
T9021 |
compound |
segment,elongation |
R5500 |
T9021 |
T9011 |
nsubj |
elongation,occurs |
R5501 |
T9022 |
T9011 |
punct |
.,occurs |
R5502 |
T9024 |
T9025 |
advmod |
Initially,have |
R5503 |
T9026 |
T9025 |
punct |
", ",have |
R5504 |
T9027 |
T9028 |
amod |
outer,segments |
R5505 |
T9028 |
T9025 |
nsubj |
segments,have |
R5506 |
T9029 |
T9030 |
det |
a,structure |
R5507 |
T9030 |
T9025 |
dobj |
structure,have |
R5508 |
T9031 |
T9032 |
npadvmod |
paddle,like |
R5509 |
T9032 |
T9030 |
amod |
like,structure |
R5510 |
T9033 |
T9032 |
punct |
-,like |
R5511 |
T9034 |
T9035 |
punct |
(,os |
R5512 |
T9035 |
T9030 |
parataxis |
os,structure |
R5513 |
T9036 |
T9035 |
dep |
C,os |
R5514 |
T9037 |
T9035 |
punct |
", ",os |
R5515 |
T9038 |
T9035 |
punct |
),os |
R5516 |
T9039 |
T9040 |
dep |
which,shed |
R5517 |
T9040 |
T9030 |
relcl |
shed,structure |
R5518 |
T9041 |
T9040 |
auxpass |
is,shed |
R5519 |
T9042 |
T9040 |
advmod |
later,shed |
R5520 |
T9043 |
T9044 |
punct |
(,os |
R5521 |
T9044 |
T9040 |
parataxis |
os,shed |
R5522 |
T9045 |
T9044 |
dep |
E,os |
R5523 |
T9046 |
T9044 |
punct |
", ",os |
R5524 |
T9047 |
T9044 |
punct |
),os |
R5525 |
T9048 |
T9025 |
punct |
.,have |
R5526 |
T9050 |
T9051 |
prep |
In,observed |
R5527 |
T9052 |
T9053 |
nmod |
Crx,photoreceptors |
R5528 |
T9053 |
T9050 |
pobj |
photoreceptors,In |
R5529 |
T9054 |
T9052 |
punct |
-,Crx |
R5530 |
T9055 |
T9052 |
punct |
/,Crx |
R5531 |
T9056 |
T9052 |
punct |
-,Crx |
R5532 |
T9057 |
T9051 |
punct |
", ",observed |
R5533 |
T9058 |
T9059 |
amod |
few,cilia |
R5534 |
T9059 |
T9051 |
nsubjpass |
cilia,observed |
R5535 |
T9060 |
T9059 |
amod |
connecting,cilia |
R5536 |
T9061 |
T9051 |
auxpass |
were,observed |
R5537 |
T9062 |
T9051 |
prep |
at,observed |
R5538 |
T9063 |
T9062 |
pobj |
P7,at |
R5539 |
T9064 |
T9065 |
punct |
(,cc |
R5540 |
T9065 |
T9051 |
parataxis |
cc,observed |
R5541 |
T9066 |
T9065 |
dep |
B,cc |
R5542 |
T9067 |
T9065 |
punct |
", ",cc |
R5543 |
T9068 |
T9065 |
punct |
),cc |
R5544 |
T9069 |
T9051 |
punct |
.,observed |
R5545 |
T9071 |
T9072 |
prep |
After,were |
R5546 |
T9073 |
T9071 |
pobj |
P7,After |
R5547 |
T9074 |
T9072 |
punct |
", ",were |
R5548 |
T9075 |
T9076 |
amod |
connecting,cilia |
R5549 |
T9076 |
T9072 |
nsubj |
cilia,were |
R5550 |
T9077 |
T9078 |
advmod |
more,numerous |
R5551 |
T9078 |
T9072 |
acomp |
numerous,were |
R5552 |
T9079 |
T9072 |
cc |
and,were |
R5553 |
T9080 |
T9081 |
advmod |
occasionally,noted |
R5554 |
T9081 |
T9072 |
conj |
noted,were |
R5555 |
T9082 |
T9083 |
det |
a,segment |
R5556 |
T9083 |
T9081 |
nsubjpass |
segment,noted |
R5557 |
T9084 |
T9083 |
amod |
malformed,segment |
R5558 |
T9085 |
T9083 |
amod |
outer,segment |
R5559 |
T9086 |
T9081 |
auxpass |
was,noted |
R5560 |
T9087 |
T9081 |
advcl |
extending,noted |
R5561 |
T9088 |
T9087 |
prep |
from,extending |
R5562 |
T9089 |
T9090 |
det |
a,cilium |
R5563 |
T9090 |
T9088 |
pobj |
cilium,from |
R5564 |
T9091 |
T9090 |
amod |
connecting,cilium |
R5565 |
T9092 |
T9093 |
punct |
(,cc* |
R5566 |
T9093 |
T9081 |
parataxis |
cc*,noted |
R5567 |
T9094 |
T9093 |
dep |
D,cc* |
R5568 |
T9095 |
T9094 |
cc |
and,D |
R5569 |
T9096 |
T9094 |
conj |
F,D |
R5570 |
T9097 |
T9093 |
punct |
", ",cc* |
R5571 |
T9098 |
T9093 |
punct |
),cc* |
R5572 |
T9099 |
T9081 |
punct |
.,noted |
R5573 |
T9101 |
T9102 |
nsubjpass |
These,observed |
R5574 |
T9103 |
T9102 |
auxpass |
were,observed |
R5575 |
T9104 |
T9102 |
advmod |
rarely,observed |
R5576 |
T9105 |
T9102 |
prep |
in,observed |
R5577 |
T9106 |
T9105 |
pobj |
Crx,in |
R5578 |
T9107 |
T9106 |
punct |
+,Crx |
R5579 |
T9108 |
T9106 |
punct |
/,Crx |
R5580 |
T9109 |
T9106 |
punct |
+,Crx |
R5581 |
T9110 |
T9102 |
cc |
and,observed |
R5582 |
T9111 |
T9112 |
advmod |
only,at |
R5583 |
T9112 |
T9110 |
prep |
at,and |
R5584 |
T9113 |
T9112 |
pobj |
P14,at |
R5585 |
T9114 |
T9115 |
punct |
(,cc* |
R5586 |
T9115 |
T9102 |
parataxis |
cc*,observed |
R5587 |
T9116 |
T9115 |
dep |
C,cc* |
R5588 |
T9117 |
T9115 |
punct |
", ",cc* |
R5589 |
T9118 |
T9115 |
punct |
),cc* |
R5590 |
T9119 |
T9102 |
punct |
.,observed |
R5591 |
T9121 |
T9122 |
prep |
At,noted |
R5592 |
T9123 |
T9121 |
pobj |
P21,At |
R5593 |
T9124 |
T9122 |
punct |
", ",noted |
R5594 |
T9125 |
T9126 |
advmod |
abnormally,long |
R5595 |
T9126 |
T9127 |
amod |
long,cilia |
R5596 |
T9127 |
T9122 |
nsubjpass |
cilia,noted |
R5597 |
T9128 |
T9127 |
amod |
connecting,cilia |
R5598 |
T9129 |
T9122 |
auxpass |
are,noted |
R5599 |
T9130 |
T9122 |
prep |
in,noted |
R5600 |
T9131 |
T9130 |
pobj |
Crx,in |
R5601 |
T9132 |
T9131 |
punct |
-,Crx |
R5602 |
T9133 |
T9131 |
punct |
/,Crx |
R5603 |
T9134 |
T9131 |
punct |
-,Crx |
R5604 |
T9135 |
T9136 |
punct |
(,cc |
R5605 |
T9136 |
T9122 |
parataxis |
cc,noted |
R5606 |
T9137 |
T9136 |
dep |
F,cc |
R5607 |
T9138 |
T9136 |
punct |
", ",cc |
R5608 |
T9139 |
T9136 |
punct |
),cc |
R5609 |
T9140 |
T9122 |
punct |
.,noted |
R5610 |
T9142 |
T9143 |
compound |
Scale,bars |
R5611 |
T9143 |
T9144 |
nsubj |
bars,μm |
R5612 |
T9145 |
T9144 |
punct |
=,μm |
R5613 |
T9146 |
T9144 |
nummod |
10,μm |
R5616 |
T9204 |
T9205 |
compound |
Transmission,micrographs |
R5617 |
T9206 |
T9205 |
compound |
electron,micrographs |
R5618 |
T9207 |
T9205 |
prep |
of,micrographs |
R5619 |
T9208 |
T9209 |
nmod |
Crx,photoreceptors |
R5620 |
T9209 |
T9207 |
pobj |
photoreceptors,of |
R5621 |
T9210 |
T9208 |
punct |
-,Crx |
R5622 |
T9211 |
T9208 |
punct |
/,Crx |
R5623 |
T9212 |
T9208 |
punct |
-,Crx |
R5624 |
T9213 |
T9205 |
prep |
in,micrographs |
R5625 |
T9214 |
T9215 |
det |
the,layer |
R5626 |
T9215 |
T9213 |
pobj |
layer,in |
R5627 |
T9216 |
T9215 |
compound |
photoreceptor,layer |
R5628 |
T9217 |
T9205 |
prep |
at,micrographs |
R5629 |
T9218 |
T9217 |
pobj |
P7,at |
R5630 |
T9219 |
T9205 |
punct |
.,micrographs |
R5631 |
T9221 |
T9222 |
punct |
(,A |
R5632 |
T9222 |
T9223 |
meta |
A,layer |
R5633 |
T9224 |
T9222 |
punct |
),A |
R5634 |
T9225 |
T9223 |
compound |
Photoreceptor,layer |
R5635 |
T9226 |
T9223 |
prep |
of,layer |
R5636 |
T9227 |
T9228 |
nmod |
Crx,retina |
R5637 |
T9228 |
T9226 |
pobj |
retina,of |
R5638 |
T9229 |
T9227 |
punct |
+,Crx |
R5639 |
T9230 |
T9227 |
punct |
/,Crx |
R5640 |
T9231 |
T9227 |
punct |
+,Crx |
R5641 |
T9232 |
T9223 |
acl |
demonstrating,layer |
R5642 |
T9233 |
T9234 |
amod |
nascent,structures |
R5643 |
T9234 |
T9237 |
nsubj |
structures,emerging |
R5644 |
T9235 |
T9236 |
amod |
outer,segment |
R5645 |
T9236 |
T9234 |
compound |
segment,structures |
R5646 |
T9237 |
T9232 |
ccomp |
emerging,demonstrating |
R5647 |
T9238 |
T9239 |
punct |
(,arrow |
R5648 |
T9239 |
T9237 |
parataxis |
arrow,emerging |
R5649 |
T9240 |
T9239 |
punct |
),arrow |
R5650 |
T9241 |
T9237 |
prep |
from,emerging |
R5651 |
T9242 |
T9243 |
nmod |
photoreceptor,cilia |
R5652 |
T9243 |
T9241 |
pobj |
cilia,from |
R5653 |
T9244 |
T9243 |
amod |
connecting,cilia |
R5654 |
T9245 |
T9243 |
punct |
(,cilia |
R5655 |
T9246 |
T9243 |
appos |
cc,cilia |
R5656 |
T9247 |
T9243 |
punct |
),cilia |
R5657 |
T9248 |
T9223 |
punct |
.,layer |
R5658 |
T9250 |
T9251 |
punct |
(,B |
R5659 |
T9251 |
T9252 |
meta |
B,observed |
R5660 |
T9253 |
T9251 |
punct |
),B |
R5661 |
T9254 |
T9255 |
nmod |
Crx,photoreceptors |
R5662 |
T9255 |
T9259 |
nsubj |
photoreceptors,exhibited |
R5663 |
T9256 |
T9254 |
punct |
-,Crx |
R5664 |
T9257 |
T9254 |
punct |
/,Crx |
R5665 |
T9258 |
T9254 |
punct |
-,Crx |
R5666 |
T9259 |
T9252 |
ccomp |
exhibited,observed |
R5667 |
T9260 |
T9261 |
amod |
connecting,cilia |
R5668 |
T9261 |
T9259 |
dobj |
cilia,exhibited |
R5669 |
T9262 |
T9261 |
punct |
(,cilia |
R5670 |
T9263 |
T9261 |
appos |
cc,cilia |
R5671 |
T9264 |
T9259 |
punct |
),exhibited |
R5672 |
T9265 |
T9259 |
prep |
at,exhibited |
R5673 |
T9266 |
T9267 |
det |
this,stage |
R5674 |
T9267 |
T9265 |
pobj |
stage,at |
R5675 |
T9268 |
T9267 |
amod |
early,stage |
R5676 |
T9269 |
T9252 |
punct |
", ",observed |
R5677 |
T9270 |
T9252 |
advmod |
however,observed |
R5678 |
T9271 |
T9252 |
punct |
", ",observed |
R5679 |
T9272 |
T9273 |
amod |
nascent,structures |
R5680 |
T9273 |
T9252 |
nsubjpass |
structures,observed |
R5681 |
T9274 |
T9275 |
amod |
outer,segment |
R5682 |
T9275 |
T9273 |
compound |
segment,structures |
R5683 |
T9276 |
T9252 |
auxpass |
were,observed |
R5684 |
T9277 |
T9252 |
neg |
not,observed |
R5685 |
T9278 |
T9252 |
punct |
.,observed |
R5686 |
T9280 |
T9281 |
compound |
Scale,Bar |
R5687 |
T9281 |
T9282 |
nsubj |
Bar,μm |
R5688 |
T9283 |
T9282 |
punct |
=,μm |
R5689 |
T9284 |
T9282 |
nummod |
1,μm |
R5690 |
T9285 |
T9282 |
punct |
.,μm |
R5691 |
T9319 |
T9320 |
amod |
Scanning,microscopy |
R5692 |
T9321 |
T9320 |
compound |
electron,microscopy |
R5693 |
T9322 |
T9320 |
prep |
of,microscopy |
R5694 |
T9323 |
T9324 |
nmod |
peripherin,photoreceptors |
R5695 |
T9324 |
T9322 |
pobj |
photoreceptors,of |
R5696 |
T9325 |
T9323 |
punct |
-,peripherin |
R5697 |
T9326 |
T9323 |
punct |
/,peripherin |
R5698 |
T9327 |
T9323 |
punct |
-,peripherin |
R5699 |
T9328 |
T9329 |
punct |
(,A |
R5700 |
T9329 |
T9323 |
parataxis |
A,peripherin |
R5701 |
T9330 |
T9329 |
punct |
),A |
R5702 |
T9331 |
T9323 |
cc |
and,peripherin |
R5703 |
T9332 |
T9323 |
conj |
rhodopsin,peripherin |
R5704 |
T9333 |
T9332 |
punct |
-,rhodopsin |
R5705 |
T9334 |
T9332 |
punct |
/,rhodopsin |
R5706 |
T9335 |
T9332 |
punct |
-,rhodopsin |
R5707 |
T9336 |
T9337 |
punct |
(,B |
R5708 |
T9337 |
T9332 |
parataxis |
B,rhodopsin |
R5709 |
T9338 |
T9337 |
punct |
),B |
R5710 |
T9339 |
T9320 |
prep |
at,microscopy |
R5711 |
T9340 |
T9339 |
pobj |
P21,at |
R5712 |
T9341 |
T9320 |
punct |
", ",microscopy |
R5713 |
T9342 |
T9320 |
acl |
viewed,microscopy |
R5714 |
T9343 |
T9342 |
prep |
from,viewed |
R5715 |
T9344 |
T9345 |
det |
the,side |
R5716 |
T9345 |
T9343 |
pobj |
side,from |
R5717 |
T9346 |
T9345 |
amod |
scleral,side |
R5718 |
T9347 |
T9348 |
mark |
with,removed |
R5719 |
T9348 |
T9342 |
advcl |
removed,viewed |
R5720 |
T9349 |
T9350 |
det |
the,epithelium |
R5721 |
T9350 |
T9348 |
nsubj |
epithelium,removed |
R5722 |
T9351 |
T9350 |
amod |
pigmented,epithelium |
R5723 |
T9352 |
T9320 |
punct |
.,microscopy |
R5724 |
T9355 |
T9354 |
punct |
", ",cc |
R5725 |
T9356 |
T9357 |
amod |
connecting,cilium |
R5726 |
T9357 |
T9354 |
appos |
cilium,cc |
R5727 |
T9358 |
T9354 |
punct |
.,cc |
R5728 |
T9361 |
T9360 |
punct |
", ",is |
R5729 |
T9362 |
T9363 |
amod |
inner,segment |
R5730 |
T9363 |
T9360 |
appos |
segment,is |
R5731 |
T9364 |
T9360 |
punct |
.,is |
R5732 |
T9366 |
T9367 |
compound |
Scale,bar |
R5733 |
T9367 |
T9368 |
nsubj |
bar,μm |
R5734 |
T9369 |
T9368 |
punct |
=,μm |
R5735 |
T9370 |
T9368 |
nummod |
10,μm |
R5736 |
T9371 |
T9368 |
punct |
.,μm |
R5743 |
T9460 |
T9461 |
compound |
Transmission,micrographs |
R5744 |
T9462 |
T9461 |
compound |
electron,micrographs |
R5745 |
T9463 |
T9461 |
prep |
of,micrographs |
R5746 |
T9464 |
T9465 |
det |
the,layer |
R5747 |
T9465 |
T9463 |
pobj |
layer,of |
R5748 |
T9466 |
T9467 |
amod |
outer,plexiform |
R5749 |
T9467 |
T9465 |
compound |
plexiform,layer |
R5750 |
T9468 |
T9461 |
prep |
in,micrographs |
R5751 |
T9469 |
T9470 |
nmod |
Crx,retinas |
R5752 |
T9470 |
T9468 |
pobj |
retinas,in |
R5753 |
T9471 |
T9469 |
punct |
-,Crx |
R5754 |
T9472 |
T9469 |
punct |
/,Crx |
R5755 |
T9473 |
T9469 |
punct |
-,Crx |
R5756 |
T9474 |
T9461 |
punct |
.,micrographs |
R5757 |
T9476 |
T9477 |
punct |
(,A |
R5758 |
T9477 |
T9478 |
meta |
A,were |
R5759 |
T9479 |
T9477 |
punct |
),A |
R5760 |
T9480 |
T9478 |
prep |
In,were |
R5761 |
T9481 |
T9482 |
nmod |
Crx,retina |
R5762 |
T9482 |
T9480 |
pobj |
retina,In |
R5763 |
T9483 |
T9481 |
punct |
+,Crx |
R5764 |
T9484 |
T9481 |
punct |
/,Crx |
R5765 |
T9485 |
T9481 |
punct |
+,Crx |
R5766 |
T9486 |
T9478 |
prep |
at,were |
R5767 |
T9487 |
T9486 |
pobj |
P21,at |
R5768 |
T9488 |
T9478 |
punct |
", ",were |
R5769 |
T9489 |
T9490 |
advmod |
newly,formed |
R5770 |
T9490 |
T9491 |
amod |
formed,spherules |
R5771 |
T9491 |
T9478 |
nsubj |
spherules,were |
R5772 |
T9492 |
T9491 |
compound |
rod,spherules |
R5773 |
T9493 |
T9478 |
acomp |
abundant,were |
R5774 |
T9494 |
T9495 |
punct |
(,demonstrates |
R5775 |
T9495 |
T9478 |
parataxis |
demonstrates,were |
R5776 |
T9496 |
T9495 |
nsubj |
arrow,demonstrates |
R5777 |
T9497 |
T9498 |
nummod |
one,example |
R5778 |
T9498 |
T9495 |
dobj |
example,demonstrates |
R5779 |
T9499 |
T9495 |
punct |
),demonstrates |
R5780 |
T9500 |
T9478 |
punct |
.,were |
R5781 |
T9502 |
T9503 |
det |
The,spherules |
R5782 |
T9503 |
T9504 |
nsubj |
spherules,were |
R5783 |
T9505 |
T9506 |
npadvmod |
club,shaped |
R5784 |
T9506 |
T9504 |
acomp |
shaped,were |
R5785 |
T9507 |
T9506 |
punct |
-,shaped |
R5786 |
T9508 |
T9504 |
cc |
and,were |
R5787 |
T9509 |
T9504 |
conj |
contained,were |
R5788 |
T9510 |
T9511 |
det |
a,synapse |
R5789 |
T9511 |
T9509 |
dobj |
synapse,contained |
R5790 |
T9512 |
T9511 |
amod |
single,synapse |
R5791 |
T9513 |
T9511 |
amod |
invaginating,synapse |
R5792 |
T9514 |
T9511 |
prep |
with,synapse |
R5793 |
T9515 |
T9516 |
nummod |
one,complex |
R5794 |
T9516 |
T9514 |
pobj |
complex,with |
R5795 |
T9517 |
T9516 |
compound |
ribbon,complex |
R5796 |
T9518 |
T9504 |
punct |
.,were |
R5797 |
T9520 |
T9521 |
compound |
Cone,terminals |
R5798 |
T9521 |
T9522 |
nsubj |
terminals,form |
R5799 |
T9523 |
T9524 |
amod |
large,pedicles |
R5800 |
T9524 |
T9522 |
dobj |
pedicles,form |
R5801 |
T9525 |
T9524 |
punct |
", ",pedicles |
R5802 |
T9526 |
T9524 |
amod |
flat,pedicles |
R5803 |
T9527 |
T9528 |
dep |
that,contain |
R5804 |
T9528 |
T9524 |
relcl |
contain,pedicles |
R5805 |
T9529 |
T9530 |
amod |
many,synapses |
R5806 |
T9530 |
T9528 |
dobj |
synapses,contain |
R5807 |
T9531 |
T9530 |
amod |
invaginating,synapses |
R5808 |
T9532 |
T9530 |
prep |
with,synapses |
R5809 |
T9533 |
T9534 |
amod |
separate,structures |
R5810 |
T9534 |
T9532 |
pobj |
structures,with |
R5811 |
T9535 |
T9534 |
compound |
ribbon,structures |
R5812 |
T9536 |
T9522 |
punct |
.,form |
R5813 |
T9538 |
T9539 |
det |
These,terminals |
R5814 |
T9539 |
T9540 |
nsubj |
terminals,were |
R5815 |
T9541 |
T9542 |
advmod |
more,scarce |
R5816 |
T9542 |
T9540 |
acomp |
scarce,were |
R5817 |
T9543 |
T9542 |
punct |
", ",scarce |
R5818 |
T9544 |
T9542 |
cc |
but,scarce |
R5819 |
T9545 |
T9542 |
conj |
apparent,scarce |
R5820 |
T9546 |
T9540 |
prep |
in,were |
R5821 |
T9547 |
T9548 |
nmod |
Crx,retinas |
R5822 |
T9548 |
T9546 |
pobj |
retinas,in |
R5823 |
T9549 |
T9547 |
punct |
+,Crx |
R5824 |
T9550 |
T9547 |
punct |
/,Crx |
R5825 |
T9551 |
T9547 |
punct |
+,Crx |
R5826 |
T9552 |
T9540 |
prep |
at,were |
R5827 |
T9553 |
T9552 |
pobj |
P21,at |
R5828 |
T9554 |
T9555 |
punct |
(,example |
R5829 |
T9555 |
T9553 |
parataxis |
example,P21 |
R5830 |
T9556 |
T9555 |
nummod |
one,example |
R5831 |
T9557 |
T9555 |
prep |
in,example |
R5832 |
T9558 |
T9557 |
pobj |
box,in |
R5833 |
T9559 |
T9555 |
punct |
),example |
R5834 |
T9560 |
T9540 |
punct |
.,were |
R5835 |
T9562 |
T9563 |
punct |
(,B |
R5836 |
T9563 |
T9564 |
meta |
B,appeared |
R5837 |
T9565 |
T9563 |
punct |
),B |
R5838 |
T9566 |
T9564 |
prep |
In,appeared |
R5839 |
T9567 |
T9568 |
det |
the,layer |
R5840 |
T9568 |
T9566 |
pobj |
layer,In |
R5841 |
T9569 |
T9568 |
amod |
outer,layer |
R5842 |
T9570 |
T9568 |
compound |
plexiform,layer |
R5843 |
T9571 |
T9568 |
punct |
(,layer |
R5844 |
T9572 |
T9568 |
appos |
OPL,layer |
R5845 |
T9573 |
T9568 |
punct |
),layer |
R5846 |
T9574 |
T9568 |
prep |
of,layer |
R5847 |
T9575 |
T9576 |
nmod |
Crx,retinas |
R5848 |
T9576 |
T9574 |
pobj |
retinas,of |
R5849 |
T9577 |
T9575 |
punct |
-,Crx |
R5850 |
T9578 |
T9575 |
punct |
/,Crx |
R5851 |
T9579 |
T9575 |
punct |
-,Crx |
R5852 |
T9580 |
T9564 |
punct |
", ",appeared |
R5853 |
T9581 |
T9582 |
compound |
photoreceptor,terminals |
R5854 |
T9582 |
T9564 |
nsubj |
terminals,appeared |
R5855 |
T9583 |
T9584 |
advmod |
highly,disorganized |
R5856 |
T9584 |
T9564 |
oprd |
disorganized,appeared |
R5857 |
T9585 |
T9564 |
prep |
at,appeared |
R5858 |
T9586 |
T9585 |
pobj |
P21,at |
R5859 |
T9587 |
T9588 |
punct |
(,arrows |
R5860 |
T9588 |
T9564 |
parataxis |
arrows,appeared |
R5861 |
T9589 |
T9588 |
punct |
),arrows |
R5862 |
T9590 |
T9564 |
punct |
.,appeared |
R5863 |
T9592 |
T9593 |
advmod |
Well,formed |
R5864 |
T9593 |
T9595 |
amod |
formed,pedicles |
R5865 |
T9594 |
T9593 |
punct |
-,formed |
R5866 |
T9595 |
T9596 |
nsubj |
pedicles,were |
R5867 |
T9597 |
T9595 |
cc |
and,pedicles |
R5868 |
T9598 |
T9595 |
conj |
spherules,pedicles |
R5869 |
T9599 |
T9596 |
neg |
not,were |
R5870 |
T9600 |
T9596 |
acomp |
evident,were |
R5871 |
T9601 |
T9596 |
punct |
.,were |
R5872 |
T9603 |
T9604 |
amod |
Putative,terminals |
R5873 |
T9604 |
T9605 |
nsubj |
terminals,were |
R5874 |
T9606 |
T9604 |
acl |
containing,terminals |
R5875 |
T9607 |
T9608 |
npadvmod |
ribbon,like |
R5876 |
T9608 |
T9610 |
amod |
like,structures |
R5877 |
T9609 |
T9608 |
punct |
-,like |
R5878 |
T9610 |
T9606 |
dobj |
structures,containing |
R5879 |
T9611 |
T9605 |
acomp |
apparent,were |
R5880 |
T9612 |
T9605 |
punct |
", ",were |
R5881 |
T9613 |
T9605 |
advcl |
suggesting,were |
R5882 |
T9614 |
T9615 |
advmod |
at,least |
R5883 |
T9615 |
T9616 |
advmod |
least,limited |
R5884 |
T9616 |
T9617 |
amod |
limited,generation |
R5885 |
T9617 |
T9613 |
dobj |
generation,suggesting |
R5886 |
T9618 |
T9617 |
prep |
of,generation |
R5887 |
T9619 |
T9620 |
compound |
synapse,components |
R5888 |
T9620 |
T9618 |
pobj |
components,of |
R5889 |
T9621 |
T9605 |
punct |
.,were |
R5890 |
T9623 |
T9624 |
amod |
Many,terminals |
R5891 |
T9624 |
T9625 |
nsubj |
terminals,appeared |
R5892 |
T9626 |
T9627 |
aux |
to,contain |
R5893 |
T9627 |
T9625 |
xcomp |
contain,appeared |
R5894 |
T9628 |
T9629 |
amod |
multiple,structures |
R5895 |
T9629 |
T9627 |
dobj |
structures,contain |
R5896 |
T9630 |
T9631 |
npadvmod |
ribbon,like |
R5897 |
T9631 |
T9629 |
amod |
like,structures |
R5898 |
T9632 |
T9631 |
punct |
-,like |
R5899 |
T9633 |
T9629 |
punct |
", ",structures |
R5900 |
T9634 |
T9635 |
advmod |
instead,of |
R5901 |
T9635 |
T9629 |
prep |
of,structures |
R5902 |
T9636 |
T9637 |
det |
a,ribbon |
R5903 |
T9637 |
T9635 |
pobj |
ribbon,of |
R5904 |
T9638 |
T9637 |
amod |
singule,ribbon |
R5905 |
T9639 |
T9625 |
punct |
.,appeared |
R5906 |
T9641 |
T9642 |
prep |
For,contained |
R5907 |
T9643 |
T9641 |
pobj |
example,For |
R5908 |
T9644 |
T9642 |
punct |
", ",contained |
R5909 |
T9645 |
T9646 |
nmod |
terminal,1 |
R5910 |
T9646 |
T9642 |
nsubj |
1,contained |
R5911 |
T9647 |
T9646 |
cc |
and,1 |
R5912 |
T9648 |
T9646 |
conj |
2,1 |
R5913 |
T9649 |
T9650 |
nummod |
two,ribbons |
R5914 |
T9650 |
T9642 |
dobj |
ribbons,contained |
R5915 |
T9651 |
T9650 |
appos |
each,ribbons |
R5916 |
T9652 |
T9642 |
punct |
", ",contained |
R5917 |
T9653 |
T9654 |
mark |
whereas,appeared |
R5918 |
T9654 |
T9642 |
advcl |
appeared,contained |
R5919 |
T9655 |
T9654 |
nsubj |
terminal,appeared |
R5920 |
T9656 |
T9655 |
nummod |
3,terminal |
R5921 |
T9657 |
T9658 |
aux |
to,contain |
R5922 |
T9658 |
T9654 |
xcomp |
contain,appeared |
R5923 |
T9659 |
T9660 |
advmod |
only,one |
R5924 |
T9660 |
T9658 |
dobj |
one,contain |
R5925 |
T9661 |
T9642 |
punct |
.,contained |
R5926 |
T9664 |
T9663 |
punct |
", ",opl |
R5927 |
T9665 |
T9666 |
amod |
outer,layer |
R5928 |
T9666 |
T9663 |
appos |
layer,opl |
R5929 |
T9667 |
T9666 |
compound |
plexiform,layer |
R5930 |
T9668 |
T9663 |
punct |
.,opl |
R5931 |
T9670 |
T9671 |
compound |
Scale,bar |
R5932 |
T9671 |
T9672 |
nsubj |
bar,μm |
R5933 |
T9673 |
T9672 |
punct |
=,μm |
R5934 |
T9674 |
T9672 |
nummod |
2,μm |
R5935 |
T9675 |
T9672 |
punct |
.,μm |
R5938 |
T9811 |
T9812 |
compound |
Transmission,micrographs |
R5939 |
T9813 |
T9812 |
compound |
electron,micrographs |
R5940 |
T9814 |
T9812 |
prep |
of,micrographs |
R5941 |
T9815 |
T9816 |
det |
the,layer |
R5942 |
T9816 |
T9814 |
pobj |
layer,of |
R5943 |
T9817 |
T9818 |
amod |
outer,plexiform |
R5944 |
T9818 |
T9816 |
compound |
plexiform,layer |
R5945 |
T9819 |
T9812 |
prep |
in,micrographs |
R5946 |
T9820 |
T9821 |
nmod |
Crx,retinas |
R5947 |
T9821 |
T9819 |
pobj |
retinas,in |
R5948 |
T9822 |
T9820 |
punct |
-,Crx |
R5949 |
T9823 |
T9820 |
punct |
/,Crx |
R5950 |
T9824 |
T9820 |
punct |
-,Crx |
R5951 |
T9825 |
T9812 |
prep |
at,micrographs |
R5952 |
T9826 |
T9825 |
pobj |
P21,at |
R5953 |
T9827 |
T9812 |
punct |
.,micrographs |
R5954 |
T9829 |
T9830 |
punct |
(,A |
R5955 |
T9830 |
T9831 |
meta |
A,contained |
R5956 |
T9832 |
T9830 |
punct |
),A |
R5957 |
T9833 |
T9834 |
nmod |
Crx,spherules |
R5958 |
T9834 |
T9831 |
nsubj |
spherules,contained |
R5959 |
T9835 |
T9833 |
punct |
+,Crx |
R5960 |
T9836 |
T9833 |
punct |
/,Crx |
R5961 |
T9837 |
T9833 |
punct |
+,Crx |
R5962 |
T9838 |
T9834 |
compound |
rod,spherules |
R5963 |
T9839 |
T9840 |
det |
a,synapse |
R5964 |
T9840 |
T9831 |
dobj |
synapse,contained |
R5965 |
T9841 |
T9840 |
amod |
single,synapse |
R5966 |
T9842 |
T9840 |
amod |
invaginating,synapse |
R5967 |
T9843 |
T9840 |
prep |
with,synapse |
R5968 |
T9844 |
T9845 |
nummod |
one,complex |
R5969 |
T9845 |
T9843 |
pobj |
complex,with |
R5970 |
T9846 |
T9845 |
compound |
ribbon,complex |
R5971 |
T9847 |
T9831 |
punct |
.,contained |
R5972 |
T9849 |
T9850 |
det |
The,spherule |
R5973 |
T9850 |
T9851 |
nsubj |
spherule,was |
R5974 |
T9852 |
T9853 |
det |
a,structure |
R5975 |
T9853 |
T9851 |
attr |
structure,was |
R5976 |
T9854 |
T9853 |
amod |
blunt,structure |
R5977 |
T9855 |
T9854 |
cc |
or,blunt |
R5978 |
T9856 |
T9857 |
npadvmod |
club,shaped |
R5979 |
T9857 |
T9854 |
conj |
shaped,blunt |
R5980 |
T9858 |
T9857 |
punct |
-,shaped |
R5981 |
T9859 |
T9851 |
punct |
.,was |
R5982 |
T9861 |
T9862 |
punct |
(,B |
R5983 |
T9862 |
T9863 |
meta |
B,contained |
R5984 |
T9864 |
T9862 |
punct |
),B |
R5985 |
T9865 |
T9866 |
nmod |
Crx,terminals |
R5986 |
T9866 |
T9863 |
nsubj |
terminals,contained |
R5987 |
T9867 |
T9865 |
punct |
+,Crx |
R5988 |
T9868 |
T9865 |
punct |
/,Crx |
R5989 |
T9869 |
T9865 |
punct |
+,Crx |
R5990 |
T9870 |
T9866 |
compound |
rod,terminals |
R5991 |
T9871 |
T9872 |
det |
a,structure |
R5992 |
T9872 |
T9863 |
dobj |
structure,contained |
R5993 |
T9873 |
T9872 |
amod |
single,structure |
R5994 |
T9874 |
T9872 |
compound |
ribbon,structure |
R5995 |
T9875 |
T9872 |
punct |
(,structure |
R5996 |
T9876 |
T9872 |
appos |
r,structure |
R5997 |
T9877 |
T9863 |
punct |
),contained |
R5998 |
T9878 |
T9863 |
punct |
.,contained |
R5999 |
T9880 |
T9881 |
nummod |
Two,processes |
R6000 |
T9881 |
T9882 |
nsubj |
processes,contacted |
R6001 |
T9883 |
T9881 |
punct |
", ",processes |
R6002 |
T9884 |
T9881 |
prep |
from,processes |
R6003 |
T9885 |
T9886 |
amod |
horizontal,cells |
R6004 |
T9886 |
T9884 |
pobj |
cells,from |
R6005 |
T9887 |
T9886 |
punct |
(,cells |
R6006 |
T9888 |
T9886 |
appos |
h,cells |
R6007 |
T9889 |
T9882 |
punct |
),contacted |
R6008 |
T9890 |
T9882 |
punct |
", ",contacted |
R6009 |
T9891 |
T9892 |
det |
the,rod |
R6010 |
T9892 |
T9882 |
dobj |
rod,contacted |
R6011 |
T9893 |
T9882 |
advmod |
laterally,contacted |
R6012 |
T9894 |
T9882 |
punct |
.,contacted |
R6013 |
T9896 |
T9897 |
det |
An,process |
R6014 |
T9897 |
T9899 |
nsubjpass |
process,situated |
R6015 |
T9898 |
T9897 |
amod |
additional,process |
R6016 |
T9900 |
T9897 |
punct |
", ",process |
R6017 |
T9901 |
T9902 |
det |
the,dendrite |
R6018 |
T9902 |
T9897 |
appos |
dendrite,process |
R6019 |
T9903 |
T9902 |
amod |
postsynaptic,dendrite |
R6020 |
T9904 |
T9902 |
amod |
bipolar,dendrite |
R6021 |
T9905 |
T9902 |
punct |
(,dendrite |
R6022 |
T9906 |
T9902 |
appos |
b,dendrite |
R6023 |
T9907 |
T9899 |
punct |
),situated |
R6024 |
T9908 |
T9899 |
punct |
", ",situated |
R6025 |
T9909 |
T9899 |
auxpass |
was,situated |
R6026 |
T9910 |
T9911 |
advmod |
more,centrally |
R6027 |
T9911 |
T9899 |
advmod |
centrally,situated |
R6028 |
T9912 |
T9899 |
punct |
.,situated |
R6029 |
T9914 |
T9915 |
nsubjpass |
Terminals,filled |
R6030 |
T9916 |
T9915 |
auxpass |
were,filled |
R6031 |
T9917 |
T9915 |
prep |
with,filled |
R6032 |
T9918 |
T9919 |
amod |
synaptic,vesicles |
R6033 |
T9919 |
T9917 |
pobj |
vesicles,with |
R6034 |
T9920 |
T9915 |
punct |
.,filled |
R6035 |
T9922 |
T9923 |
nummod |
One,vesicle |
R6036 |
T9923 |
T9925 |
nsubjpass |
vesicle,observed |
R6037 |
T9924 |
T9923 |
amod |
coated,vesicle |
R6038 |
T9926 |
T9923 |
acl |
originatinf,vesicle |
R6039 |
T9927 |
T9926 |
prep |
from,originatinf |
R6040 |
T9928 |
T9929 |
det |
the,membrane |
R6041 |
T9929 |
T9927 |
pobj |
membrane,from |
R6042 |
T9930 |
T9929 |
compound |
cell,membrane |
R6043 |
T9931 |
T9925 |
auxpass |
was,observed |
R6044 |
T9932 |
T9933 |
punct |
(,arrow |
R6045 |
T9933 |
T9925 |
parataxis |
arrow,observed |
R6046 |
T9934 |
T9933 |
punct |
),arrow |
R6047 |
T9935 |
T9925 |
punct |
.,observed |
R6048 |
T9937 |
T9938 |
punct |
(,C |
R6049 |
T9938 |
T9939 |
meta |
C,appeared |
R6050 |
T9940 |
T9938 |
punct |
),C |
R6051 |
T9941 |
T9939 |
prep |
In,appeared |
R6052 |
T9942 |
T9943 |
det |
the,OPL |
R6053 |
T9943 |
T9941 |
pobj |
OPL,In |
R6054 |
T9944 |
T9943 |
prep |
of,OPL |
R6055 |
T9945 |
T9946 |
nmod |
Crx,retinas |
R6056 |
T9946 |
T9944 |
pobj |
retinas,of |
R6057 |
T9947 |
T9945 |
punct |
-,Crx |
R6058 |
T9948 |
T9945 |
punct |
/,Crx |
R6059 |
T9949 |
T9945 |
punct |
-,Crx |
R6060 |
T9950 |
T9939 |
punct |
", ",appeared |
R6061 |
T9951 |
T9952 |
compound |
photoreceptor,terminals |
R6062 |
T9952 |
T9939 |
nsubj |
terminals,appeared |
R6063 |
T9953 |
T9954 |
advmod |
highly,disorganized |
R6064 |
T9954 |
T9939 |
oprd |
disorganized,appeared |
R6065 |
T9955 |
T9939 |
punct |
.,appeared |
R6066 |
T9957 |
T9958 |
amod |
Putative,terminals |
R6067 |
T9958 |
T9959 |
nsubj |
terminals,were |
R6068 |
T9960 |
T9958 |
acl |
containing,terminals |
R6069 |
T9961 |
T9962 |
amod |
synaptic,vesicles |
R6070 |
T9962 |
T9960 |
dobj |
vesicles,containing |
R6071 |
T9963 |
T9962 |
cc |
and,vesicles |
R6072 |
T9964 |
T9965 |
npadvmod |
ribbon,like |
R6073 |
T9965 |
T9967 |
amod |
like,structures |
R6074 |
T9966 |
T9965 |
punct |
-,like |
R6075 |
T9967 |
T9962 |
conj |
structures,vesicles |
R6076 |
T9968 |
T9959 |
acomp |
apparent,were |
R6077 |
T9969 |
T9970 |
punct |
(,arrows |
R6078 |
T9970 |
T9959 |
parataxis |
arrows,were |
R6079 |
T9971 |
T9970 |
punct |
),arrows |
R6080 |
T9972 |
T9959 |
punct |
", ",were |
R6081 |
T9973 |
T9959 |
advcl |
suggesting,were |
R6082 |
T9974 |
T9975 |
advmod |
at,least |
R6083 |
T9975 |
T9976 |
advmod |
least,limited |
R6084 |
T9976 |
T9977 |
amod |
limited,generation |
R6085 |
T9977 |
T9973 |
dobj |
generation,suggesting |
R6086 |
T9978 |
T9977 |
prep |
of,generation |
R6087 |
T9979 |
T9980 |
compound |
synapse,components |
R6088 |
T9980 |
T9978 |
pobj |
components,of |
R6089 |
T9981 |
T9959 |
punct |
.,were |
R6090 |
T9983 |
T9984 |
advmod |
However,observed |
R6091 |
T9985 |
T9984 |
punct |
", ",observed |
R6092 |
T9986 |
T9987 |
advmod |
well,formed |
R6093 |
T9987 |
T9988 |
amod |
formed,spherules |
R6094 |
T9988 |
T9984 |
nsubjpass |
spherules,observed |
R6095 |
T9989 |
T9988 |
cc |
and,spherules |
R6096 |
T9990 |
T9988 |
conj |
pedicles,spherules |
R6097 |
T9991 |
T9984 |
auxpass |
were,observed |
R6098 |
T9992 |
T9984 |
neg |
not,observed |
R6099 |
T9993 |
T9984 |
punct |
.,observed |
R6100 |
T9995 |
T9996 |
advmod |
Further,appeared |
R6101 |
T9997 |
T9996 |
punct |
", ",appeared |
R6102 |
T9998 |
T9999 |
amod |
many,terminals |
R6103 |
T9999 |
T9996 |
nsubj |
terminals,appeared |
R6104 |
T10000 |
T10001 |
aux |
to,contain |
R6105 |
T10001 |
T9996 |
xcomp |
contain,appeared |
R6106 |
T10002 |
T10003 |
amod |
multiple,structures |
R6107 |
T10003 |
T10001 |
dobj |
structures,contain |
R6108 |
T10004 |
T10005 |
npadvmod |
ribbon,like |
R6109 |
T10005 |
T10003 |
amod |
like,structures |
R6110 |
T10006 |
T10005 |
punct |
-,like |
R6111 |
T10007 |
T10003 |
punct |
(,structures |
R6112 |
T10008 |
T10003 |
appos |
r,structures |
R6113 |
T10009 |
T9996 |
punct |
),appeared |
R6114 |
T10010 |
T9996 |
punct |
.,appeared |
R6115 |
T10012 |
T10013 |
det |
The,majority |
R6116 |
T10013 |
T10014 |
nsubjpass |
majority,associated |
R6117 |
T10015 |
T10013 |
prep |
of,majority |
R6118 |
T10016 |
T10017 |
det |
these,ribbons |
R6119 |
T10017 |
T10015 |
pobj |
ribbons,of |
R6120 |
T10018 |
T10014 |
auxpass |
were,associated |
R6121 |
T10019 |
T10014 |
neg |
not,associated |
R6122 |
T10020 |
T10014 |
prep |
with,associated |
R6123 |
T10021 |
T10022 |
det |
the,membrane |
R6124 |
T10022 |
T10020 |
pobj |
membrane,with |
R6125 |
T10023 |
T10022 |
amod |
synaptic,membrane |
R6126 |
T10024 |
T10014 |
punct |
", ",associated |
R6127 |
T10025 |
T10014 |
cc |
but,associated |
R6128 |
T10026 |
T10025 |
advmod |
instead,but |
R6129 |
T10027 |
T10028 |
auxpass |
were,found |
R6130 |
T10028 |
T10014 |
conj |
found,associated |
R6131 |
T10029 |
T10030 |
amod |
free,floating |
R6132 |
T10030 |
T10028 |
advcl |
floating,found |
R6133 |
T10031 |
T10028 |
cc |
and,found |
R6134 |
T10032 |
T10028 |
punct |
", ",found |
R6135 |
T10033 |
T10034 |
prep |
in,were |
R6136 |
T10034 |
T10028 |
conj |
were,found |
R6137 |
T10035 |
T10036 |
det |
some,instances |
R6138 |
T10036 |
T10033 |
pobj |
instances,in |
R6139 |
T10037 |
T10034 |
punct |
", ",were |
R6140 |
T10038 |
T10034 |
acomp |
perinuclear,were |
R6141 |
T10039 |
T10040 |
punct |
(,arrow |
R6142 |
T10040 |
T10034 |
parataxis |
arrow,were |
R6143 |
T10041 |
T10040 |
dep |
D,arrow |
R6144 |
T10042 |
T10040 |
punct |
", ",arrow |
R6145 |
T10043 |
T10040 |
punct |
),arrow |
R6146 |
T10044 |
T10014 |
punct |
.,associated |
R6147 |
T10047 |
T10046 |
punct |
", ",H |
R6148 |
T10048 |
T10049 |
amod |
horizontal,cell |
R6149 |
T10049 |
T10046 |
appos |
cell,H |
R6150 |
T10050 |
T10046 |
punct |
;,H |
R6151 |
T10051 |
T10046 |
appos |
B,H |
R6152 |
T10052 |
T10051 |
punct |
", ",B |
R6153 |
T10053 |
T10054 |
amod |
bipolar,cell |
R6154 |
T10054 |
T10051 |
appos |
cell,B |
R6155 |
T10055 |
T10046 |
punct |
;,H |
R6156 |
T10056 |
T10046 |
appos |
N,H |
R6157 |
T10057 |
T10056 |
punct |
", ",N |
R6158 |
T10058 |
T10056 |
appos |
nucleus,N |
R6159 |
T10059 |
T10046 |
punct |
;,H |
R6160 |
T10060 |
T10046 |
appos |
r,H |
R6161 |
T10061 |
T10060 |
punct |
", ",r |
R6162 |
T10062 |
T10060 |
appos |
ribbon,r |
R6163 |
T10063 |
T10046 |
punct |
.,H |
R6164 |
T10065 |
T10066 |
punct |
(,A |
R6165 |
T10066 |
T10067 |
meta |
A,nm |
R6166 |
T10067 |
T10073 |
ccomp |
nm,nm |
R6167 |
T10068 |
T10066 |
punct |
),A |
R6168 |
T10069 |
T10070 |
compound |
Scale,bar |
R6169 |
T10070 |
T10067 |
nsubj |
bar,nm |
R6170 |
T10071 |
T10067 |
punct |
=,nm |
R6171 |
T10072 |
T10067 |
nummod |
500,nm |
R6172 |
T10074 |
T10073 |
punct |
", ",nm |
R6173 |
T10075 |
T10076 |
punct |
(,B |
R6174 |
T10076 |
T10077 |
meta |
B,nm |
R6175 |
T10077 |
T10073 |
ccomp |
nm,nm |
R6176 |
T10078 |
T10076 |
punct |
),B |
R6177 |
T10079 |
T10080 |
compound |
Scale,bar |
R6178 |
T10080 |
T10077 |
nsubj |
bar,nm |
R6179 |
T10081 |
T10077 |
punct |
=,nm |
R6180 |
T10082 |
T10077 |
nummod |
250,nm |
R6181 |
T10083 |
T10073 |
punct |
", ",nm |
R6182 |
T10084 |
T10085 |
punct |
(,C |
R6183 |
T10085 |
T10073 |
meta |
C,nm |
R6184 |
T10086 |
T10085 |
cc |
and,C |
R6185 |
T10087 |
T10085 |
conj |
D,C |
R6186 |
T10088 |
T10087 |
punct |
),D |
R6187 |
T10089 |
T10090 |
compound |
Scale,bar |
R6188 |
T10090 |
T10073 |
nsubj |
bar,nm |
R6189 |
T10091 |
T10073 |
punct |
=,nm |
R6190 |
T10092 |
T10073 |
nummod |
500,nm |
R6191 |
T10093 |
T10073 |
punct |
.,nm |
R1348 |
T2590 |
T2591 |
compound |
ceptor,i |
R1349 |
T2601 |
T2600 |
parataxis |
nd,a |
R1350 |
T2607 |
T2608 |
amod |
r,segments |
R1351 |
T2611 |
T2610 |
amod |
ar,e |
R1352 |
T2615 |
T2614 |
agent |
by,joined |
R1353 |
T2616 |
T2617 |
det |
a,cilium |
R1354 |
T2617 |
T2615 |
pobj |
cilium,by |
R1355 |
T2618 |
T2617 |
amod |
non-motile,cilium |
R1356 |
T2619 |
T2617 |
amod |
connecting,cilium |
R1357 |
T2620 |
T2621 |
dep |
that,exhibits |
R1358 |
T2621 |
T2617 |
relcl |
exhibits,cilium |
R1359 |
T2622 |
T2623 |
det |
a,arrangement |
R1360 |
T2623 |
T2621 |
dobj |
arrangement,exhibits |
R1361 |
T2624 |
T2623 |
amod |
characteristic,arrangement |
R1362 |
T2625 |
T2626 |
nummod |
9,0 |
R1363 |
T2626 |
T2623 |
nummod |
0,arrangement |
R1364 |
T2627 |
T2626 |
punct |
+,0 |
R1365 |
T2628 |
T2623 |
prep |
of,arrangement |
R1366 |
T2629 |
T2630 |
compound |
microtubule,doublets |
R1367 |
T2630 |
T2628 |
pobj |
doublets,of |
R1368 |
T2631 |
T2632 |
advmod |
when,viewed |
R1369 |
T2632 |
T2621 |
advcl |
viewed,exhibits |
R1370 |
T2633 |
T2632 |
prep |
in,viewed |
R1371 |
T2634 |
T2633 |
pobj |
cross-section,in |
R1372 |
T2635 |
T2614 |
punct |
.,joined |
R1373 |
T2637 |
T2638 |
prep |
At,noted |
R1374 |
T2639 |
T2637 |
pobj |
P21,At |
R1375 |
T2640 |
T2638 |
punct |
", ",noted |
R1376 |
T2641 |
T2638 |
prep |
in,noted |
R1377 |
T2642 |
T2643 |
nmod |
Crx,retinas |
R1378 |
T2643 |
T2641 |
pobj |
retinas,in |
R1379 |
T2644 |
T2642 |
punct |
-,Crx |
R1380 |
T2645 |
T2642 |
punct |
/,Crx |
R1381 |
T2646 |
T2642 |
punct |
-,Crx |
R1382 |
T2647 |
T2638 |
punct |
", ",noted |
R1383 |
T2648 |
T2649 |
amod |
numerous,sections |
R1384 |
T2649 |
T2638 |
nsubjpass |
sections,noted |
R1385 |
T2650 |
T2649 |
compound |
cross,sections |
R1386 |
T2651 |
T2649 |
prep |
of,sections |
R1387 |
T2652 |
T2653 |
amod |
connecting,cilia |
R1388 |
T2653 |
T2651 |
pobj |
cilia,of |
R1468 |
T2741 |
T2739 |
pobj |
photoreceptors,in |
R1471 |
T2744 |
T2740 |
punct |
-,Crx |
R1472 |
T2745 |
T2725 |
punct |
.,indicate |
R1473 |
T2747 |
T2748 |
advmod |
Further,appeared |
R1474 |
T2749 |
T2748 |
punct |
", ",appeared |
R1475 |
T2750 |
T2748 |
prep |
in,appeared |
R1476 |
T2751 |
T2752 |
nmod |
Crx,retinas |
R1477 |
T2752 |
T2750 |
pobj |
retinas,in |
R1478 |
T2753 |
T2751 |
punct |
-,Crx |
R1479 |
T2754 |
T2751 |
punct |
/,Crx |
R1480 |
T2755 |
T2751 |
punct |
-,Crx |
R1481 |
T2756 |
T2757 |
det |
the,epithelium |
R1482 |
T2757 |
T2748 |
nsubj |
epithelium,appeared |
R1483 |
T2758 |
T2757 |
nmod |
retinal,epithelium |
R1484 |
T2759 |
T2757 |
amod |
pigmented,epithelium |
R1485 |
T2760 |
T2757 |
punct |
(,epithelium |
R1486 |
T2761 |
T2757 |
appos |
PE,epithelium |
R1487 |
T2762 |
T2748 |
punct |
),appeared |
R1488 |
T2763 |
T2748 |
oprd |
normal,appeared |
R1489 |
T2764 |
T2748 |
punct |
", ",appeared |
R1490 |
T2765 |
T2766 |
advmod |
at,least |
R1491 |
T2766 |
T2767 |
advmod |
least,up |
R1492 |
T2767 |
T2748 |
prep |
up,appeared |
R1493 |
T2768 |
T2767 |
prep |
to,up |
R1494 |
T2769 |
T2768 |
pobj |
P21,to |
R1495 |
T2770 |
T2771 |
punct |
(,shown |
R1496 |
T2771 |
T2769 |
parataxis |
shown,P21 |
R1497 |
T2772 |
T2771 |
nsubj |
data,shown |
R1498 |
T2773 |
T2771 |
neg |
not,shown |
R1499 |
T2774 |
T2771 |
punct |
),shown |
R1500 |
T2775 |
T2769 |
punct |
", ",P21 |
R1501 |
T2776 |
T2777 |
det |
the,age |
R1502 |
T2777 |
T2769 |
appos |
age,P21 |
R1503 |
T2778 |
T2777 |
amod |
oldest,age |
R1504 |
T2779 |
T2777 |
acl |
examined,age |
R1505 |
T2780 |
T2748 |
punct |
.,appeared |
R1506 |
T2787 |
T2786 |
oprd |
ti,i |
R1507 |
T2788 |
T2789 |
amod |
o,n |
R1508 |
T2792 |
T2791 |
pobj |
t,o |
R1509 |
T2796 |
T2795 |
parataxis |
o,c |
R1510 |
T2801 |
T2802 |
compound |
e,t |
R1511 |
T2804 |
T2805 |
compound |
e,a |
R1512 |
T2807 |
T2808 |
amod |
bs,e |
R1513 |
T2814 |
T2812 |
advcl |
o,o |
R1514 |
T2817 |
T2818 |
amod |
uter,segments |
R1515 |
T2819 |
T2816 |
punct |
", ",exhibited |
R1516 |
T2820 |
T2821 |
nmod |
Crx,retinas |
R1517 |
T2821 |
T2816 |
nsubj |
retinas,exhibited |
R1518 |
T2822 |
T2820 |
punct |
-,Crx |
R1519 |
T2823 |
T2820 |
punct |
/,Crx |
R1520 |
T2824 |
T2820 |
punct |
-,Crx |
R1521 |
T2825 |
T2826 |
nummod |
three,pathologies |
R1522 |
T2826 |
T2816 |
dobj |
pathologies,exhibited |
R1523 |
T2827 |
T2826 |
amod |
other,pathologies |
R1524 |
T2828 |
T2826 |
amod |
notable,pathologies |
R1525 |
T2829 |
T2816 |
prep |
in,exhibited |
R1526 |
T2830 |
T2831 |
det |
the,layer |
R1527 |
T2831 |
T2829 |
pobj |
layer,in |
R1528 |
T2832 |
T2833 |
amod |
outer,segment |
R1529 |
T2833 |
T2831 |
compound |
segment,layer |
R1530 |
T2834 |
T2816 |
punct |
.,exhibited |
R1531 |
T2836 |
T2837 |
advmod |
First,noted |
R1532 |
T2838 |
T2837 |
punct |
", ",noted |
R1533 |
T2839 |
T2840 |
det |
an,deposition |
R1534 |
T2840 |
T2837 |
nsubjpass |
deposition,noted |
R1535 |
T2841 |
T2840 |
amod |
abnormal,deposition |
R1536 |
T2842 |
T2840 |
prep |
of,deposition |
R1537 |
T2843 |
T2842 |
pobj |
matrix,of |
R1538 |
T2844 |
T2843 |
prep |
of,matrix |
R1539 |
T2845 |
T2846 |
amod |
unknown,identity |
R1540 |
T2846 |
T2844 |
pobj |
identity,of |
R1541 |
T2847 |
T2837 |
auxpass |
was,noted |
R1971 |
T3310 |
T3308 |
pobj |
formation,of |
R1973 |
T3311 |
T3312 |
amod |
outer,segment |
R1976 |
T3312 |
T3310 |
compound |
segment,formation |
R1979 |
T3313 |
T3306 |
prep |
in,absence |
R1983 |
T3314 |
T3315 |
det |
the,mouse |
R1986 |
T3315 |
T3313 |
pobj |
mouse,in |
R1987 |
T3316 |
T3315 |
compound |
Crx,mouse |
R1989 |
T3317 |
T3315 |
compound |
mutant,mouse |
R1993 |
T3318 |
T3306 |
punct |
", ",absence |
R1997 |
T3319 |
T3306 |
cc |
and,absence |
R2001 |
T3320 |
T3321 |
det |
the,arrest |
R2002 |
T3321 |
T3306 |
conj |
arrest,absence |
R2003 |
T3322 |
T3321 |
prep |
of,arrest |
R2004 |
T3323 |
T3322 |
pobj |
development,of |
R2007 |
T3324 |
T3323 |
prep |
of,development |
R2010 |
T3325 |
T3326 |
det |
the,appendage |
R2014 |
T3326 |
T3324 |
pobj |
appendage,of |
R2018 |
T3327 |
T3326 |
compound |
photoreceptor,appendage |
R2022 |
T3328 |
T3321 |
prep |
at,arrest |
R2028 |
T3329 |
T3330 |
det |
the,stage |
R2033 |
T3330 |
T3328 |
pobj |
stage,at |
R2036 |
T3331 |
T3330 |
compound |
elongation,stage |
R2040 |
T3332 |
T3330 |
prep |
of,stage |
R2042 |
T3333 |
T3334 |
amod |
outer,segment |
R2046 |
T3334 |
T3335 |
compound |
segment,formation |
R2049 |
T3335 |
T3332 |
pobj |
formation,of |
R2053 |
T3336 |
T3304 |
punct |
.,demonstrate |
R1964 |
T3356 |
T3355 |
prep |
o,ph |
R1972 |
T3367 |
T3368 |
det |
the,photoreceptors |
R1974 |
T3368 |
T3366 |
pobj |
photoreceptors,f |
R1975 |
T3369 |
T3368 |
amod |
malformed,photoreceptors |
R1977 |
T3370 |
T3368 |
nmod |
Crx,photoreceptors |
R1978 |
T3371 |
T3370 |
punct |
-,Crx |
R1980 |
T3372 |
T3370 |
punct |
/,Crx |
R1981 |
T3373 |
T3370 |
punct |
-,Crx |
R1982 |
T3374 |
T3365 |
auxpass |
was,compared |
R1984 |
T3375 |
T3365 |
prep |
to,compared |
R1985 |
T3376 |
T3377 |
nmod |
rhodopsin,photoreceptors |