PMC:5400024 / 16976-17769 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/5400024","sourcedb":"PMC","sourceid":"5400024","source_url":"https://www.ncbi.nlm.nih.gov/pmc/5400024","text":"To assess the integrity of the pulmonary vascular compartment, we measured Syndecan-1 levels as a marker of endothelial glycocaylx disruption. Syndecan-1 levels were significantly lower in perfusate samples from transplanted donor lungs: mean (T) = 111 (pg/ml) (SD 98, n = 24) compared to mean (NT) = 281 (pg/ml) (SD 219, n = 40) [t(62) = 4.14, P \u003c 0.001] (Fig. 3).\nFigure 3: Protein expressions in perfusate and BALF from transplanted and non-transplanted EVLP donor lungs. Interleaved scatter plots with molecular marker levels expressed in (pg/ml) and lines representing means. *P\u003c0.1. **P\u003c0.05. ***P\u003c0.001. BALF: bronchoalveolar lavage fluid; EVLP: ex vivo lung perfusion; IL: interleukin; TNF-α: tumour necrosis factor alpha; LDH: lactate dehydrogenase; HMGB-1: high-mobility group box-1.","divisions":[{"label":"label","span":{"begin":366,"end":375}}],"tracks":[{"project":"testtesttest","denotations":[{"id":"T133","span":{"begin":231,"end":236},"obj":"Body_part"},{"id":"T134","span":{"begin":468,"end":473},"obj":"Body_part"},{"id":"T135","span":{"begin":640,"end":645},"obj":"Body_part"},{"id":"T136","span":{"begin":661,"end":665},"obj":"Body_part"}],"attributes":[{"id":"A133","pred":"uberon_id","subj":"T133","obj":"http://purl.obolibrary.org/obo/UBERON_0000170"},{"id":"A134","pred":"uberon_id","subj":"T134","obj":"http://purl.obolibrary.org/obo/UBERON_0000170"},{"id":"A135","pred":"uberon_id","subj":"T135","obj":"http://purl.obolibrary.org/obo/UBERON_0006314"},{"id":"A136","pred":"uberon_id","subj":"T136","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"subj":"T133","pred":"source","obj":"testtesttest"},{"subj":"T134","pred":"source","obj":"testtesttest"},{"subj":"T135","pred":"source","obj":"testtesttest"},{"subj":"T136","pred":"source","obj":"testtesttest"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"testtesttest","color":"#cc93ec","default":true}]}]}}