PMC:539973 / 757-2329 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/539973","sourcedb":"PMC","sourceid":"539973","source_url":"https://www.ncbi.nlm.nih.gov/pmc/539973","text":"INTRODUCTION\nSequencing of a new genome is not a sensational event anymore: while the first genome sequences determined several years ago often made it to the front page of the New York Times, nowadays even getting them published in major scientific journals is becoming increasingly difficult. The novelty of genomic data as such is certainly passé, but their usefulness remains intact, and perhaps is even increasing owing to virtually unlimited opportunities for comparative genomic analysis and large-scale data mining. At the same time, due to the sheer amount of genomic data currently available, the task of maintaining an up-to-date and complete genome analysis database represents a significant challenge.\nThe MIPS group (now Institute for Bioinformatics) in Munich began to provide exhaustive automatic analysis of all publicly available genomes in 1996, when only five genomic sequences were published (1). The main mission of the PEDANT genome database is to fill the gap between manually curated high-quality protein sequence databases, such as SWISS-PROT (2) or PIR International (3), and the enormous amounts of other protein sequences produced by genome sequencing projects at an ever increasing pace. For example, release 44.0 of SWISS-PROT contains 153 871 manually annotated proteins, while the total number of currently known protein sequences stands at roughly 2 500 000. Since the aforementioned gap is quickly growing, it is probably safe to say that the majority of protein sequences will never be subjected to in-depth annotation by human experts.","divisions":[{"label":"title","span":{"begin":0,"end":12}},{"label":"p","span":{"begin":13,"end":714}}],"tracks":[{"project":"2_test","denotations":[{"id":"15608204-12520024-76722512","span":{"begin":1070,"end":1071},"obj":"12520024"},{"id":"15608204-14681371-76722513","span":{"begin":1095,"end":1096},"obj":"14681371"}],"attributes":[{"subj":"15608204-12520024-76722512","pred":"source","obj":"2_test"},{"subj":"15608204-14681371-76722513","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"2_test","color":"#d6ec93","default":true}]}]}}