> top > docs > PMC:539297 > spans > 590-1416 > annotations

PMC:539297 / 590-1416 JSONTXT

Annnotations TAB JSON ListView MergeView

craft-ca-core-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T75 61-75 CL:0000540 denotes neuronal cells
T76 97-102 NCBITaxon:10088 denotes mouse
T77 103-112 UBERON:0002037 denotes cerebella
T78 153-155 UBERON:0002037 denotes Cb
T79 155-159 PR:000005591 denotes Cln3
T80 200-208 CL:0000540 denotes neuronal
T81 264-269 PR:000010124 denotes MAP-2
T82 274-278 PR:000006252 denotes NeuN
T83 289-295 CL:0000540 denotes neuron
T84 319-321 UBERON:0002037 denotes Cb
T85 321-325 PR:000005591 denotes Cln3
T86 348-355 GO:0010467 denotes express
T87 377-385 PR:000005591 denotes battenin
T88 427-443 PR:000022190 denotes ATPase subunit c
T89 509-520 PR:000006025 denotes cathepsin D
T90 615-624 GO:0005764 denotes lysosomal
T91 664-675 GO:0006897 denotes endocytosis
T92 701-713 GO:0005739 denotes mitochondria
T93 798-807 MOP:0000568 denotes oxidative

craft-sa-dev

Id Subject Object Predicate Lexical cue
T274 0-2 TO denotes To
T275 3-12 VB denotes elucidate
T276 80-84 VBD denotes used
T277 13-16 DT denotes the
T278 17-29 NNS denotes consequences
T279 30-32 IN denotes of
T280 33-36 DT denotes the
T281 49-57 NN denotes mutation
T282 37-43 JJ denotes common
T283 44-48 NN denotes JNCL
T284 58-60 IN denotes in
T285 61-69 JJ denotes neuronal
T286 70-75 NNS denotes cells
T287 75-77 , denotes ,
T288 77-79 PRP denotes we
T289 85-87 NN denotes P4
T290 103-112 NNS denotes cerebella
T291 88-93 VB denotes knock
T292 93-94 HYPH denotes -
T293 94-96 RP denotes in
T294 97-102 NN denotes mouse
T295 113-115 TO denotes to
T296 116-125 VB denotes establish
T297 126-139 RB denotes conditionally
T298 140-152 VBN denotes immortalized
T299 224-229 NNS denotes lines
T300 153-159 NN denotes CbCln3
T301 160-164 JJ denotes wild
T302 165-169 NN denotes type
T303 164-165 HYPH denotes -
T304 169-171 , denotes ,
T305 171-183 JJ denotes heterozygous
T306 183-185 , denotes ,
T307 185-188 CC denotes and
T308 189-199 JJ denotes homozygous
T309 200-208 JJ denotes neuronal
T310 209-218 NN denotes precursor
T311 219-223 NN denotes cell
T312 229-231 , denotes ,
T313 231-236 WDT denotes which
T314 244-258 VBN denotes differentiated
T315 237-240 MD denotes can
T316 241-243 VB denotes be
T317 259-263 IN denotes into
T318 264-267 NN denotes MAP
T319 279-287 JJ denotes positive
T320 267-268 HYPH denotes -
T321 268-269 CD denotes 2
T322 270-273 CC denotes and
T323 274-278 NN denotes NeuN
T324 278-279 HYPH denotes -
T325 301-306 NNS denotes cells
T326 287-289 , denotes ,
T327 289-295 NN denotes neuron
T328 296-300 JJ denotes like
T329 295-296 HYPH denotes -
T330 306-307 . denotes .
T331 307-444 sentence denotes Homozygous CbCln3Δex7/8 precursor cells express low levels of mutant battenin and, when aged at confluency, accumulate ATPase subunit c.
T332 308-318 JJ denotes Homozygous
T333 342-347 NNS denotes cells
T334 319-329 NN denotes CbCln3Δex7
T335 329-330 HYPH denotes /
T336 330-331 CD denotes 8
T337 332-341 NN denotes precursor
T338 348-355 VBP denotes express
T339 356-359 JJ denotes low
T340 360-366 NNS denotes levels
T341 367-369 IN denotes of
T342 370-376 NN denotes mutant
T343 377-385 NN denotes battenin
T344 386-389 CC denotes and
T345 389-391 , denotes ,
T346 391-395 WRB denotes when
T347 396-400 VBN denotes aged
T348 416-426 VBP denotes accumulate
T349 401-403 IN denotes at
T350 404-414 NN denotes confluency
T351 414-416 , denotes ,
T352 427-433 NN denotes ATPase
T353 442-443 NN denotes c
T354 434-441 NN denotes subunit
T355 443-444 . denotes .
T356 444-687 sentence denotes Recessive phenotypes are also observed at sub-confluent growth; cathepsin D transport and processing are altered, although enzyme activity is not significantly affected, lysosomal size and distribution are altered, and endocytosis is reduced.
T357 445-454 JJ denotes Recessive
T358 455-465 NNS denotes phenotypes
T359 475-483 VBN denotes observed
T360 466-469 VBP denotes are
T361 470-474 RB denotes also
T362 484-486 IN denotes at
T363 487-500 JJ denotes sub-confluent
T364 501-507 NN denotes growth
T365 507-508 : denotes ;
T366 509-518 NN denotes cathepsin
T367 519-520 NN denotes D
T368 550-557 VBN denotes altered
T369 521-530 NN denotes transport
T370 531-534 CC denotes and
T371 535-545 NN denotes processing
T372 546-549 VBP denotes are
T373 557-559 , denotes ,
T374 559-567 IN denotes although
T375 605-613 VBN denotes affected
T376 568-574 NN denotes enzyme
T377 575-583 NN denotes activity
T378 584-586 VBZ denotes is
T379 587-590 RB denotes not
T380 591-604 RB denotes significantly
T381 651-658 VBN denotes altered
T382 613-615 , denotes ,
T383 615-624 JJ denotes lysosomal
T384 625-629 NN denotes size
T385 630-633 CC denotes and
T386 634-646 NN denotes distribution
T387 647-650 VBP denotes are
T388 658-660 , denotes ,
T389 660-663 CC denotes and
T390 664-675 NN denotes endocytosis
T391 679-686 VBN denotes reduced
T392 676-678 VBZ denotes is
T393 686-687 . denotes .
T394 687-826 sentence denotes In addition, mitochondria are abnormally elongated, cellular ATP levels are decreased, and survival following oxidative stress is reduced.
T395 688-690 IN denotes In
T396 714-717 VBP denotes are
T397 691-699 NN denotes addition
T398 699-701 , denotes ,
T399 701-713 NNS denotes mitochondria
T400 718-728 RB denotes abnormally
T401 729-738 JJ denotes elongated
T402 738-740 , denotes ,
T403 740-748 JJ denotes cellular
T404 753-759 NNS denotes levels
T405 749-752 NN denotes ATP
T406 764-773 VBN denotes decreased
T407 760-763 VBP denotes are
T408 773-775 , denotes ,
T409 775-778 CC denotes and
T410 779-787 NN denotes survival
T411 818-825 VBN denotes reduced
T412 788-797 VBG denotes following
T413 798-807 JJ denotes oxidative
T414 808-814 NN denotes stress
T415 815-817 VBZ denotes is
T416 825-826 . denotes .
R92 T274 T275 aux To,elucidate
R93 T275 T276 advcl elucidate,used
R94 T277 T278 det the,consequences
R95 T278 T275 dobj consequences,elucidate
R96 T279 T278 prep of,consequences
R97 T280 T281 det the,mutation
R98 T281 T279 pobj mutation,of
R99 T282 T281 amod common,mutation
R100 T283 T281 compound JNCL,mutation
R101 T284 T278 prep in,consequences
R102 T285 T286 amod neuronal,cells
R103 T286 T284 pobj cells,in
R104 T287 T276 punct ", ",used
R105 T288 T276 nsubj we,used
R106 T289 T290 nmod P4,cerebella
R107 T290 T276 dobj cerebella,used
R108 T291 T290 amod knock,cerebella
R109 T292 T291 punct -,knock
R110 T293 T291 prt in,knock
R111 T294 T290 compound mouse,cerebella
R112 T295 T296 aux to,establish
R113 T296 T276 advcl establish,used
R114 T297 T298 advmod conditionally,immortalized
R115 T298 T299 amod immortalized,lines
R116 T299 T296 dobj lines,establish
R117 T300 T299 nmod CbCln3,lines
R118 T301 T302 amod wild,type
R119 T302 T299 nmod type,lines
R120 T303 T302 punct -,type
R121 T304 T302 punct ", ",type
R122 T305 T302 conj heterozygous,type
R123 T306 T305 punct ", ",heterozygous
R124 T307 T305 cc and,heterozygous
R125 T308 T305 conj homozygous,heterozygous
R126 T309 T310 amod neuronal,precursor
R127 T310 T299 compound precursor,lines
R128 T311 T299 compound cell,lines
R129 T312 T299 punct ", ",lines
R130 T313 T314 dep which,differentiated
R131 T314 T299 relcl differentiated,lines
R132 T315 T314 aux can,differentiated
R133 T316 T314 auxpass be,differentiated
R134 T317 T314 prep into,differentiated
R135 T318 T319 npadvmod MAP,positive
R136 T319 T325 amod positive,cells
R137 T320 T318 punct -,MAP
R138 T321 T318 nummod 2,MAP
R139 T322 T318 cc and,MAP
R140 T323 T318 conj NeuN,MAP
R141 T324 T319 punct -,positive
R142 T325 T317 pobj cells,into
R143 T326 T325 punct ", ",cells
R144 T327 T328 npadvmod neuron,like
R145 T328 T325 amod like,cells
R146 T329 T328 punct -,like
R147 T330 T276 punct .,used
R148 T332 T333 amod Homozygous,cells
R149 T333 T338 nsubj cells,express
R150 T334 T333 nmod CbCln3Δex7,cells
R151 T335 T334 punct /,CbCln3Δex7
R152 T336 T334 nummod 8,CbCln3Δex7
R153 T337 T333 compound precursor,cells
R154 T339 T340 amod low,levels
R155 T340 T338 dobj levels,express
R156 T341 T340 prep of,levels
R157 T342 T343 compound mutant,battenin
R158 T343 T341 pobj battenin,of
R159 T344 T338 cc and,express
R160 T345 T338 punct ", ",express
R161 T346 T347 advmod when,aged
R162 T347 T348 advcl aged,accumulate
R163 T348 T338 conj accumulate,express
R164 T349 T347 prep at,aged
R165 T350 T349 pobj confluency,at
R166 T351 T348 punct ", ",accumulate
R167 T352 T353 compound ATPase,c
R169 T354 T353 compound subunit,c
R170 T355 T338 punct .,express
R171 T357 T358 amod Recessive,phenotypes
R172 T358 T359 nsubjpass phenotypes,observed
R173 T360 T359 auxpass are,observed
R174 T361 T359 advmod also,observed
R175 T362 T359 prep at,observed
R176 T363 T364 amod sub-confluent,growth
R177 T364 T362 pobj growth,at
R178 T365 T359 punct ;,observed
R179 T366 T367 compound cathepsin,D
R180 T367 T368 nsubjpass D,altered
R181 T368 T359 conj altered,observed
R182 T369 T367 appos transport,D
R183 T370 T369 cc and,transport
R184 T371 T369 conj processing,transport
R185 T372 T368 auxpass are,altered
R186 T373 T368 punct ", ",altered
R187 T374 T375 mark although,affected
R188 T375 T381 advcl affected,altered
R189 T376 T377 compound enzyme,activity
R190 T377 T375 nsubjpass activity,affected
R191 T378 T375 auxpass is,affected
R192 T379 T375 neg not,affected
R193 T380 T375 advmod significantly,affected
R194 T381 T368 conj altered,altered
R195 T382 T381 punct ", ",altered
R196 T383 T384 amod lysosomal,size
R197 T384 T381 nsubjpass size,altered
R198 T385 T384 cc and,size
R199 T386 T384 conj distribution,size
R200 T387 T381 auxpass are,altered
R201 T388 T381 punct ", ",altered
R202 T389 T381 cc and,altered
R203 T390 T391 nsubjpass endocytosis,reduced
R205 T392 T391 auxpass is,reduced
R206 T393 T391 punct .,reduced
R207 T395 T396 prep In,are
R208 T397 T395 pobj addition,In
R209 T398 T396 punct ", ",are
R210 T399 T396 nsubj mitochondria,are
R211 T400 T401 advmod abnormally,elongated
R212 T401 T396 acomp elongated,are
R213 T402 T396 punct ", ",are
R214 T403 T404 amod cellular,levels
R216 T405 T404 compound ATP,levels
R218 T407 T406 auxpass are,decreased
R219 T408 T406 punct ", ",decreased
R220 T409 T406 cc and,decreased
R221 T410 T411 nsubjpass survival,reduced
R222 T411 T406 conj reduced,decreased
R223 T412 T410 prep following,survival
R224 T413 T414 amod oxidative,stress
R225 T414 T412 pobj stress,following
R226 T415 T411 auxpass is,reduced
R227 T416 T396 punct .,are
R168 T353 T348 dobj c,accumulate
R204 T391 T381 conj reduced,altered
R215 T404 T406 nsubjpass levels,decreased
R217 T406 T396 conj decreased,are

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T126 49-57 SO_EXT:sequence_alteration_entity_or_process denotes mutation
T127 61-75 CL:0000540 denotes neuronal cells
T128 70-75 CL_GO_EXT:cell denotes cells
T129 97-102 NCBITaxon:10088 denotes mouse
T130 103-112 UBERON:0002037 denotes cerebella
T131 153-155 UBERON:0002037 denotes Cb
T132 155-159 PR_EXT:000005591 denotes Cln3
T133 160-169 SO_EXT:wild_type_entity_or_quality denotes wild-type
T134 200-208 CL:0000540 denotes neuronal
T135 219-223 CL_GO_EXT:cell denotes cell
T136 244-258 GO_PATO_RO_EXT:developmental_differentiation_process_or_quality denotes differentiated
T137 264-269 PR_EXT:000010124 denotes MAP-2
T138 274-278 PR_EXT:000006252 denotes NeuN
T139 289-295 CL:0000540 denotes neuron
T140 301-306 CL_GO_EXT:cell denotes cells
T141 319-321 UBERON:0002037 denotes Cb
T142 321-325 PR_EXT:000005591 denotes Cln3
T143 342-347 CL_GO_EXT:cell denotes cells
T144 348-355 GO:0010467 denotes express
T145 370-376 SO_EXT:sequence_altered_entity_or_alteration_process denotes mutant
T146 377-385 PR_EXT:000005591 denotes battenin
T147 396-400 GO_PATO_EXT:aging_or_agedness denotes aged
T148 427-433 GO_EXT:0016887 denotes ATPase
T149 427-443 PR_EXT:000022190 denotes ATPase subunit c
T150 501-507 GO_EXT:biological_growth_entity_or_process denotes growth
T151 509-520 PR_EXT:000006025 denotes cathepsin D
T152 521-530 GO_EXT:biological_routing_or_transport denotes transport
T153 535-545 SO_EXT:sequence_alteration_process denotes processing
T154 568-574 CHEBI_GO_SO_EXT:enzyme denotes enzyme
T155 615-624 GO:0005764 denotes lysosomal
T156 664-675 GO:0006897 denotes endocytosis
T157 701-713 GO:0005739 denotes mitochondria
T158 740-748 CL_GO_EXT:cell denotes cellular
T159 749-752 CHEBI_EXT:ATP denotes ATP
T160 798-807 MOP:0000568 denotes oxidative