
PMC:539297 / 454-1027
Annnotations
craft-ca-core-dev
Below, discontinuous spans are shown in the chain model. You can change it to the bag model.
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T71 | 2-6 | PR:000005591 | denotes | Cln3 |
T72 | 22-26 | NCBITaxon:10088 | denotes | mice |
T73 | 70-77 | GO:0010467 | denotes | express |
T74 | 85-93 | PR:000005591 | denotes | battenin |
T75 | 197-211 | CL:0000540 | denotes | neuronal cells |
T76 | 233-238 | NCBITaxon:10088 | denotes | mouse |
T77 | 239-248 | UBERON:0002037 | denotes | cerebella |
T78 | 289-291 | UBERON:0002037 | denotes | Cb |
T79 | 291-295 | PR:000005591 | denotes | Cln3 |
T80 | 336-344 | CL:0000540 | denotes | neuronal |
T81 | 400-405 | PR:000010124 | denotes | MAP-2 |
T82 | 410-414 | PR:000006252 | denotes | NeuN |
T83 | 425-431 | CL:0000540 | denotes | neuron |
T84 | 455-457 | UBERON:0002037 | denotes | Cb |
T85 | 457-461 | PR:000005591 | denotes | Cln3 |
T86 | 484-491 | GO:0010467 | denotes | express |
T87 | 513-521 | PR:000005591 | denotes | battenin |
craft-sa-dev
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T246 | 2-10 | NN | denotes | Cln3Δex7 |
T247 | 22-26 | NNS | denotes | mice |
T248 | 10-11 | HYPH | denotes | / |
T249 | 11-12 | CD | denotes | 8 |
T250 | 13-18 | VB | denotes | knock |
T251 | 18-19 | HYPH | denotes | - |
T252 | 19-21 | RP | denotes | in |
T253 | 26-28 | , | denotes | , |
T254 | 28-33 | WDT | denotes | which |
T255 | 34-43 | VBP | denotes | replicate |
T256 | 44-47 | DT | denotes | the |
T257 | 60-68 | NN | denotes | mutation |
T258 | 48-54 | JJ | denotes | common |
T259 | 55-59 | NN | denotes | JNCL |
T260 | 68-70 | , | denotes | , |
T261 | 70-77 | VBP | denotes | express |
T262 | 78-84 | NN | denotes | mutant |
T263 | 85-93 | NN | denotes | battenin |
T264 | 94-97 | CC | denotes | and |
T265 | 98-105 | VBP | denotes | display |
T266 | 106-110 | NN | denotes | JNCL |
T267 | 111-115 | JJ | denotes | like |
T268 | 110-111 | HYPH | denotes | - |
T269 | 116-125 | NN | denotes | pathology |
T270 | 125-126 | . | denotes | . |
T271 | 126-135 | sentence | denotes | Results |
T272 | 128-135 | NNS | denotes | Results |
T273 | 135-443 | sentence | denotes | To elucidate the consequences of the common JNCL mutation in neuronal cells, we used P4 knock-in mouse cerebella to establish conditionally immortalized CbCln3 wild-type, heterozygous, and homozygous neuronal precursor cell lines, which can be differentiated into MAP-2 and NeuN-positive, neuron-like cells. |
T274 | 136-138 | TO | denotes | To |
T275 | 139-148 | VB | denotes | elucidate |
T276 | 216-220 | VBD | denotes | used |
T277 | 149-152 | DT | denotes | the |
T278 | 153-165 | NNS | denotes | consequences |
T279 | 166-168 | IN | denotes | of |
T280 | 169-172 | DT | denotes | the |
T281 | 185-193 | NN | denotes | mutation |
T282 | 173-179 | JJ | denotes | common |
T283 | 180-184 | NN | denotes | JNCL |
T284 | 194-196 | IN | denotes | in |
T285 | 197-205 | JJ | denotes | neuronal |
T286 | 206-211 | NNS | denotes | cells |
T287 | 211-213 | , | denotes | , |
T288 | 213-215 | PRP | denotes | we |
T289 | 221-223 | NN | denotes | P4 |
T290 | 239-248 | NNS | denotes | cerebella |
T291 | 224-229 | VB | denotes | knock |
T292 | 229-230 | HYPH | denotes | - |
T293 | 230-232 | RP | denotes | in |
T294 | 233-238 | NN | denotes | mouse |
T295 | 249-251 | TO | denotes | to |
T296 | 252-261 | VB | denotes | establish |
T297 | 262-275 | RB | denotes | conditionally |
T298 | 276-288 | VBN | denotes | immortalized |
T299 | 360-365 | NNS | denotes | lines |
T300 | 289-295 | NN | denotes | CbCln3 |
T301 | 296-300 | JJ | denotes | wild |
T302 | 301-305 | NN | denotes | type |
T303 | 300-301 | HYPH | denotes | - |
T304 | 305-307 | , | denotes | , |
T305 | 307-319 | JJ | denotes | heterozygous |
T306 | 319-321 | , | denotes | , |
T307 | 321-324 | CC | denotes | and |
T308 | 325-335 | JJ | denotes | homozygous |
T309 | 336-344 | JJ | denotes | neuronal |
T310 | 345-354 | NN | denotes | precursor |
T311 | 355-359 | NN | denotes | cell |
T312 | 365-367 | , | denotes | , |
T313 | 367-372 | WDT | denotes | which |
T314 | 380-394 | VBN | denotes | differentiated |
T315 | 373-376 | MD | denotes | can |
T316 | 377-379 | VB | denotes | be |
T317 | 395-399 | IN | denotes | into |
T318 | 400-403 | NN | denotes | MAP |
T319 | 415-423 | JJ | denotes | positive |
T320 | 403-404 | HYPH | denotes | - |
T321 | 404-405 | CD | denotes | 2 |
T322 | 406-409 | CC | denotes | and |
T323 | 410-414 | NN | denotes | NeuN |
T324 | 414-415 | HYPH | denotes | - |
T325 | 437-442 | NNS | denotes | cells |
T326 | 423-425 | , | denotes | , |
T327 | 425-431 | NN | denotes | neuron |
T328 | 432-436 | JJ | denotes | like |
T329 | 431-432 | HYPH | denotes | - |
T330 | 442-443 | . | denotes | . |
T332 | 444-454 | JJ | denotes | Homozygous |
T333 | 478-483 | NNS | denotes | cells |
T334 | 455-465 | NN | denotes | CbCln3Δex7 |
T335 | 465-466 | HYPH | denotes | / |
T336 | 466-467 | CD | denotes | 8 |
T337 | 468-477 | NN | denotes | precursor |
T338 | 484-491 | VBP | denotes | express |
T339 | 492-495 | JJ | denotes | low |
T340 | 496-502 | NNS | denotes | levels |
T341 | 503-505 | IN | denotes | of |
T342 | 506-512 | NN | denotes | mutant |
T343 | 513-521 | NN | denotes | battenin |
T344 | 522-525 | CC | denotes | and |
T345 | 525-527 | , | denotes | , |
T346 | 527-531 | WRB | denotes | when |
T347 | 532-536 | VBN | denotes | aged |
T348 | 552-562 | VBP | denotes | accumulate |
T349 | 537-539 | IN | denotes | at |
T350 | 540-550 | NN | denotes | confluency |
T351 | 550-552 | , | denotes | , |
T352 | 563-569 | NN | denotes | ATPase |
R85 | T264 | T261 | cc | and,express |
R86 | T265 | T261 | conj | display,express |
R84 | T263 | T261 | dobj | battenin,express |
R67 | T246 | T247 | nmod | Cln3Δex7,mice |
R69 | T248 | T246 | punct | /,Cln3Δex7 |
R70 | T249 | T246 | nummod | 8,Cln3Δex7 |
R71 | T250 | T247 | amod | knock,mice |
R72 | T251 | T250 | punct | -,knock |
R73 | T252 | T250 | prt | in,knock |
R74 | T253 | T247 | punct | ", ",mice |
R75 | T254 | T255 | dep | which,replicate |
R76 | T255 | T247 | relcl | replicate,mice |
R77 | T256 | T257 | det | the,mutation |
R78 | T257 | T255 | dobj | mutation,replicate |
R79 | T258 | T257 | amod | common,mutation |
R80 | T259 | T257 | compound | JNCL,mutation |
R81 | T260 | T255 | punct | ", ",replicate |
R82 | T261 | T255 | conj | express,replicate |
R83 | T262 | T263 | compound | mutant,battenin |
R87 | T266 | T267 | npadvmod | JNCL,like |
R89 | T268 | T267 | punct | -,like |
R90 | T269 | T265 | dobj | pathology,display |
R92 | T274 | T275 | aux | To,elucidate |
R93 | T275 | T276 | advcl | elucidate,used |
R94 | T277 | T278 | det | the,consequences |
R95 | T278 | T275 | dobj | consequences,elucidate |
R96 | T279 | T278 | prep | of,consequences |
R97 | T280 | T281 | det | the,mutation |
R98 | T281 | T279 | pobj | mutation,of |
R99 | T282 | T281 | amod | common,mutation |
R100 | T283 | T281 | compound | JNCL,mutation |
R101 | T284 | T278 | prep | in,consequences |
R102 | T285 | T286 | amod | neuronal,cells |
R103 | T286 | T284 | pobj | cells,in |
R104 | T287 | T276 | punct | ", ",used |
R105 | T288 | T276 | nsubj | we,used |
R106 | T289 | T290 | nmod | P4,cerebella |
R107 | T290 | T276 | dobj | cerebella,used |
R108 | T291 | T290 | amod | knock,cerebella |
R109 | T292 | T291 | punct | -,knock |
R110 | T293 | T291 | prt | in,knock |
R111 | T294 | T290 | compound | mouse,cerebella |
R112 | T295 | T296 | aux | to,establish |
R113 | T296 | T276 | advcl | establish,used |
R114 | T297 | T298 | advmod | conditionally,immortalized |
R115 | T298 | T299 | amod | immortalized,lines |
R116 | T299 | T296 | dobj | lines,establish |
R117 | T300 | T299 | nmod | CbCln3,lines |
R118 | T301 | T302 | amod | wild,type |
R119 | T302 | T299 | nmod | type,lines |
R120 | T303 | T302 | punct | -,type |
R121 | T304 | T302 | punct | ", ",type |
R122 | T305 | T302 | conj | heterozygous,type |
R123 | T306 | T305 | punct | ", ",heterozygous |
R124 | T307 | T305 | cc | and,heterozygous |
R125 | T308 | T305 | conj | homozygous,heterozygous |
R126 | T309 | T310 | amod | neuronal,precursor |
R127 | T310 | T299 | compound | precursor,lines |
R128 | T311 | T299 | compound | cell,lines |
R129 | T312 | T299 | punct | ", ",lines |
R130 | T313 | T314 | dep | which,differentiated |
R131 | T314 | T299 | relcl | differentiated,lines |
R132 | T315 | T314 | aux | can,differentiated |
R133 | T316 | T314 | auxpass | be,differentiated |
R134 | T317 | T314 | prep | into,differentiated |
R135 | T318 | T319 | npadvmod | MAP,positive |
R136 | T319 | T325 | amod | positive,cells |
R137 | T320 | T318 | punct | -,MAP |
R138 | T321 | T318 | nummod | 2,MAP |
R139 | T322 | T318 | cc | and,MAP |
R140 | T323 | T318 | conj | NeuN,MAP |
R141 | T324 | T319 | punct | -,positive |
R142 | T325 | T317 | pobj | cells,into |
R143 | T326 | T325 | punct | ", ",cells |
R144 | T327 | T328 | npadvmod | neuron,like |
R145 | T328 | T325 | amod | like,cells |
R146 | T329 | T328 | punct | -,like |
R147 | T330 | T276 | punct | .,used |
R148 | T332 | T333 | amod | Homozygous,cells |
R149 | T333 | T338 | nsubj | cells,express |
R150 | T334 | T333 | nmod | CbCln3Δex7,cells |
R151 | T335 | T334 | punct | /,CbCln3Δex7 |
R152 | T336 | T334 | nummod | 8,CbCln3Δex7 |
R153 | T337 | T333 | compound | precursor,cells |
R154 | T339 | T340 | amod | low,levels |
R155 | T340 | T338 | dobj | levels,express |
R156 | T341 | T340 | prep | of,levels |
R157 | T342 | T343 | compound | mutant,battenin |
R158 | T343 | T341 | pobj | battenin,of |
R159 | T344 | T338 | cc | and,express |
R160 | T345 | T338 | punct | ", ",express |
R161 | T346 | T347 | advmod | when,aged |
R162 | T347 | T348 | advcl | aged,accumulate |
R163 | T348 | T338 | conj | accumulate,express |
R164 | T349 | T347 | prep | at,aged |
R165 | T350 | T349 | pobj | confluency,at |
R166 | T351 | T348 | punct | ", ",accumulate |
R88 | T267 | T269 | amod | like,pathology |
craft-ca-core-ex-dev
Below, discontinuous spans are shown in the chain model. You can change it to the bag model.
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T120 | 2-6 | PR_EXT:000005591 | denotes | Cln3 |
T121 | 22-26 | NCBITaxon:10088 | denotes | mice |
T122 | 60-68 | SO_EXT:sequence_alteration_entity_or_process | denotes | mutation |
T123 | 70-77 | GO:0010467 | denotes | express |
T124 | 78-84 | SO_EXT:sequence_altered_entity_or_alteration_process | denotes | mutant |
T125 | 85-93 | PR_EXT:000005591 | denotes | battenin |
T126 | 185-193 | SO_EXT:sequence_alteration_entity_or_process | denotes | mutation |
T127 | 197-211 | CL:0000540 | denotes | neuronal cells |
T128 | 206-211 | CL_GO_EXT:cell | denotes | cells |
T129 | 233-238 | NCBITaxon:10088 | denotes | mouse |
T130 | 239-248 | UBERON:0002037 | denotes | cerebella |
T131 | 289-291 | UBERON:0002037 | denotes | Cb |
T132 | 291-295 | PR_EXT:000005591 | denotes | Cln3 |
T133 | 296-305 | SO_EXT:wild_type_entity_or_quality | denotes | wild-type |
T134 | 336-344 | CL:0000540 | denotes | neuronal |
T135 | 355-359 | CL_GO_EXT:cell | denotes | cell |
T136 | 380-394 | GO_PATO_RO_EXT:developmental_differentiation_process_or_quality | denotes | differentiated |
T137 | 400-405 | PR_EXT:000010124 | denotes | MAP-2 |
T138 | 410-414 | PR_EXT:000006252 | denotes | NeuN |
T139 | 425-431 | CL:0000540 | denotes | neuron |
T140 | 437-442 | CL_GO_EXT:cell | denotes | cells |
T141 | 455-457 | UBERON:0002037 | denotes | Cb |
T142 | 457-461 | PR_EXT:000005591 | denotes | Cln3 |
T143 | 478-483 | CL_GO_EXT:cell | denotes | cells |
T144 | 484-491 | GO:0010467 | denotes | express |
T145 | 506-512 | SO_EXT:sequence_altered_entity_or_alteration_process | denotes | mutant |
T146 | 513-521 | PR_EXT:000005591 | denotes | battenin |
T147 | 532-536 | GO_PATO_EXT:aging_or_agedness | denotes | aged |
T148 | 563-569 | GO_EXT:0016887 | denotes | ATPase |