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PMC:539297 / 21950-22549 JSONTXT

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craft-ca-core-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T4173 581-589 CL:0000540 denotes neuronal
T4152 0-2 UBERON:0002037 denotes Cb
T4153 2-6 PR:000005591 denotes Cln3
T4154 13-23 UBERON:0002037 denotes cerebellar
T4155 60-71 SO:0000704 denotes genetically
T4156 81-87 CL:0000540 denotes neuron
T4157 130-132 UBERON:0002037 denotes Cb
T4158 132-136 PR:000005591 denotes Cln3
T4159 149-156 GO:0010467 denotes express
T4160 164-172 PR:000005591 denotes battenin
T4161 191-204 GO:0005739 denotes mitochondrial
T4162 191-221 PR:000022190 denotes mitochondrial ATPase subunit c
T4163 241-255 GO:0007569 denotes aging of cells
T4164 327-336 _FRAGMENT denotes endosomal
T4165 347-355 GO:0010008 denotes membrane
T4166 356-367 GO:0016197 denotes trafficking
T4167 337-355 GO:0005765 denotes lysosomal membrane
T4168 337-346 _FRAGMENT denotes lysosomal
T4169 356-367 GO:0007041 denotes trafficking
T4170 347-367 GO:0055085 denotes membrane trafficking
T4171 380-393 GO:0005739 denotes mitochondrial
T4172 420-429 PR:000022190 denotes subunit c
R2367 T4166 T4164 _lexicallyChainedTo trafficking,endosomal
R2368 T4169 T4168 _lexicallyChainedTo trafficking,lysosomal
R2366 T4165 T4164 _lexicallyChainedTo membrane,endosomal

craft-sa-dev

Id Subject Object Predicate Lexical cue
T4415 0-10 NN denotes CbCln3Δex7
T4416 34-39 NNS denotes cells
T4417 10-11 HYPH denotes /
T4418 11-12 CD denotes 8
T4419 13-23 JJ denotes cerebellar
T4420 24-33 NN denotes precursor
T4421 40-49 VBP denotes represent
T4422 50-53 DT denotes the
T4423 104-109 NN denotes model
T4424 54-59 JJ denotes first
T4425 60-71 RB denotes genetically
T4426 72-80 JJ denotes accurate
T4427 81-87 NN denotes neuron
T4428 88-95 JJ denotes derived
T4429 87-88 HYPH denotes -
T4430 96-103 NN denotes culture
T4431 110-112 IN denotes of
T4432 113-117 NN denotes JNCL
T4433 117-118 . denotes .
T4434 118-270 sentence denotes Homozygous CbCln3Δex7/8 cells express mutant battenin and JNCL-hallmark mitochondrial ATPase subunit c accumulation, upon aging of cells at confluency.
T4435 119-129 JJ denotes Homozygous
T4436 143-148 NNS denotes cells
T4437 130-140 NN denotes CbCln3Δex7
T4438 140-141 HYPH denotes /
T4439 141-142 CD denotes 8
T4440 149-156 VBP denotes express
T4441 157-163 NN denotes mutant
T4442 164-172 NN denotes battenin
T4443 173-176 CC denotes and
T4444 177-181 NN denotes JNCL
T4445 182-190 NN denotes hallmark
T4446 181-182 HYPH denotes -
T4447 222-234 NN denotes accumulation
T4448 191-204 JJ denotes mitochondrial
T4449 205-211 NN denotes ATPase
T4450 212-219 NN denotes subunit
T4451 220-221 NN denotes c
T4452 234-236 , denotes ,
T4453 236-240 IN denotes upon
T4454 241-246 NN denotes aging
T4455 247-249 IN denotes of
T4456 250-255 NNS denotes cells
T4457 256-258 IN denotes at
T4458 259-269 NN denotes confluency
T4459 269-270 . denotes .
T4460 270-467 sentence denotes Moreover, this is the first study to indicate recessive endosomal/lysosomal membrane trafficking defects and mitochondrial dysfunction that precedes subunit c deposition in an accurate JNCL model.
T4461 271-279 RB denotes Moreover
T4462 286-288 VBZ denotes is
T4463 279-281 , denotes ,
T4464 281-285 DT denotes this
T4465 289-292 DT denotes the
T4466 299-304 NN denotes study
T4467 293-298 JJ denotes first
T4468 305-307 TO denotes to
T4469 308-316 VB denotes indicate
T4470 317-326 JJ denotes recessive
T4471 368-375 NNS denotes defects
T4472 327-336 JJ denotes endosomal
T4473 337-346 JJ denotes lysosomal
T4474 336-337 HYPH denotes /
T4475 347-355 NN denotes membrane
T4476 356-367 NN denotes trafficking
T4477 376-379 CC denotes and
T4478 380-393 JJ denotes mitochondrial
T4479 394-405 NN denotes dysfunction
T4480 406-410 WDT denotes that
T4481 411-419 VBZ denotes precedes
T4482 420-427 NN denotes subunit
T4483 428-429 NN denotes c
T4484 430-440 NN denotes deposition
T4485 441-443 IN denotes in
T4486 444-446 DT denotes an
T4487 461-466 NN denotes model
T4488 447-455 JJ denotes accurate
T4489 456-460 NN denotes JNCL
T4490 466-467 . denotes .
T4491 467-599 sentence denotes Importantly, these defects are likely to be early events in the JNCL disease process and may particularly impact neuronal function.
T4492 468-479 RB denotes Importantly
T4493 495-498 VBP denotes are
T4494 479-481 , denotes ,
T4495 481-486 DT denotes these
T4496 487-494 NNS denotes defects
T4497 499-505 JJ denotes likely
T4498 506-508 TO denotes to
T4499 509-511 VB denotes be
T4500 512-517 JJ denotes early
T4501 518-524 NNS denotes events
T4502 525-527 IN denotes in
T4503 528-531 DT denotes the
T4504 545-552 NN denotes process
T4505 532-536 NN denotes JNCL
T4506 537-544 NN denotes disease
T4507 553-556 CC denotes and
T4508 557-560 MD denotes may
T4509 574-580 VB denotes impact
T4510 561-573 RB denotes particularly
T4511 581-589 JJ denotes neuronal
T4512 590-598 NN denotes function
T4513 598-599 . denotes .
R2382 T4415 T4416 nmod CbCln3Δex7,cells
R2383 T4416 T4421 nsubj cells,represent
R2384 T4417 T4415 punct /,CbCln3Δex7
R2385 T4418 T4415 nummod 8,CbCln3Δex7
R2386 T4419 T4420 amod cerebellar,precursor
R2387 T4420 T4416 compound precursor,cells
R2388 T4422 T4423 det the,model
R2389 T4423 T4421 dobj model,represent
R2390 T4424 T4423 amod first,model
R2391 T4425 T4426 advmod genetically,accurate
R2392 T4426 T4423 amod accurate,model
R2393 T4427 T4428 npadvmod neuron,derived
R2394 T4428 T4423 amod derived,model
R2395 T4429 T4428 punct -,derived
R2396 T4430 T4423 compound culture,model
R2397 T4431 T4423 prep of,model
R2398 T4432 T4431 pobj JNCL,of
R2399 T4433 T4421 punct .,represent
R2400 T4435 T4436 amod Homozygous,cells
R2401 T4436 T4440 nsubj cells,express
R2402 T4437 T4436 nmod CbCln3Δex7,cells
R2403 T4438 T4437 punct /,CbCln3Δex7
R2404 T4439 T4437 nummod 8,CbCln3Δex7
R2405 T4441 T4442 compound mutant,battenin
R2406 T4442 T4440 dobj battenin,express
R2407 T4443 T4442 cc and,battenin
R2408 T4444 T4445 nmod JNCL,hallmark
R2409 T4445 T4447 nmod hallmark,accumulation
R2410 T4446 T4445 punct -,hallmark
R2411 T4447 T4442 conj accumulation,battenin
R2412 T4448 T4447 amod mitochondrial,accumulation
R2413 T4449 T4447 compound ATPase,accumulation
R2414 T4450 T4451 compound subunit,c
R2415 T4451 T4447 compound c,accumulation
R2416 T4452 T4440 punct ", ",express
R2417 T4453 T4440 prep upon,express
R2418 T4454 T4453 pobj aging,upon
R2419 T4455 T4454 prep of,aging
R2420 T4456 T4455 pobj cells,of
R2421 T4457 T4456 prep at,cells
R2422 T4458 T4457 pobj confluency,at
R2423 T4459 T4440 punct .,express
R2424 T4461 T4462 advmod Moreover,is
R2425 T4463 T4462 punct ", ",is
R2426 T4464 T4462 nsubj this,is
R2427 T4465 T4466 det the,study
R2428 T4466 T4462 attr study,is
R2429 T4467 T4466 amod first,study
R2430 T4468 T4469 aux to,indicate
R2431 T4469 T4466 advcl indicate,study
R2432 T4470 T4471 amod recessive,defects
R2433 T4471 T4469 dobj defects,indicate
R2434 T4472 T4473 amod endosomal,lysosomal
R2435 T4473 T4475 amod lysosomal,membrane
R2436 T4474 T4473 punct /,lysosomal
R2437 T4475 T4471 compound membrane,defects
R2438 T4476 T4471 compound trafficking,defects
R2439 T4477 T4471 cc and,defects
R2440 T4478 T4479 amod mitochondrial,dysfunction
R2441 T4479 T4471 conj dysfunction,defects
R2442 T4480 T4481 dep that,precedes
R2443 T4481 T4471 relcl precedes,defects
R2444 T4482 T4483 compound subunit,c
R2445 T4483 T4484 compound c,deposition
R2446 T4484 T4481 dobj deposition,precedes
R2447 T4485 T4481 prep in,precedes
R2448 T4486 T4487 det an,model
R2449 T4487 T4485 pobj model,in
R2450 T4488 T4487 amod accurate,model
R2451 T4489 T4487 compound JNCL,model
R2452 T4490 T4462 punct .,is
R2453 T4492 T4493 advmod Importantly,are
R2454 T4494 T4493 punct ", ",are
R2455 T4495 T4496 det these,defects
R2456 T4496 T4493 nsubj defects,are
R2457 T4497 T4493 acomp likely,are
R2458 T4498 T4499 aux to,be
R2459 T4499 T4497 xcomp be,likely
R2460 T4500 T4501 amod early,events
R2461 T4501 T4499 attr events,be
R2462 T4502 T4501 prep in,events
R2463 T4503 T4504 det the,process
R2464 T4504 T4502 pobj process,in
R2465 T4505 T4504 compound JNCL,process
R2466 T4506 T4504 compound disease,process
R2467 T4507 T4493 cc and,are
R2468 T4508 T4509 aux may,impact
R2469 T4509 T4493 conj impact,are
R2470 T4510 T4509 advmod particularly,impact
R2471 T4511 T4512 amod neuronal,function
R2472 T4512 T4509 dobj function,impact
R2473 T4513 T4493 punct .,are

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T4263 0-2 UBERON:0002037 denotes Cb
T4264 2-6 PR_EXT:000005591 denotes Cln3
T4265 13-23 UBERON:0002037 denotes cerebellar
T4266 34-39 CL_GO_EXT:cell denotes cells
T4267 60-71 SO_EXT:0000704 denotes genetically
T4268 81-87 CL:0000540 denotes neuron
T4269 130-132 UBERON:0002037 denotes Cb
T4270 132-136 PR_EXT:000005591 denotes Cln3
T4271 143-148 CL_GO_EXT:cell denotes cells
T4272 149-156 GO:0010467 denotes express
T4273 157-163 SO_EXT:sequence_altered_entity_or_alteration_process denotes mutant
T4274 164-172 PR_EXT:000005591 denotes battenin
T4275 191-204 GO:0005739 denotes mitochondrial
T4276 191-221 PR_EXT:000022190 denotes mitochondrial ATPase subunit c
T4277 205-211 GO_EXT:0016887 denotes ATPase
T4278 241-255 GO:0007569 denotes aging of cells
T4279 250-255 CL_GO_EXT:cell denotes cells
T4280 327-336 _FRAGMENT denotes endosomal
T4281 347-355 GO:0010008 denotes membrane
T4282 356-367 GO:0016197 denotes trafficking
T4283 337-355 GO:0005765 denotes lysosomal membrane
T4284 337-346 _FRAGMENT denotes lysosomal
T4285 356-367 GO:0007041 denotes trafficking
T4286 347-367 GO:0055085 denotes membrane trafficking
T4287 380-393 GO:0005739 denotes mitochondrial
T4288 420-429 PR_EXT:000022190 denotes subunit c
T4289 581-589 CL:0000540 denotes neuronal
R2374 T4281 T4280 _lexicallyChainedTo membrane,endosomal
R2375 T4282 T4280 _lexicallyChainedTo trafficking,endosomal
R2376 T4285 T4284 _lexicallyChainedTo trafficking,lysosomal