![Logo](/assets/logo-d3f1fdf60522f0983e71f9fcc720cb7da5b55c0b748ed5bded3d2fbf81387bf0.png)
PMC:539297 / 19848-20181
Annnotations
craft-ca-core-dev
{"project":"craft-ca-core-dev","denotations":[{"id":"T3196","span":{"begin":67,"end":69},"obj":"UBERON:0002037"},{"id":"T3197","span":{"begin":69,"end":73},"obj":"PR:000005591"},{"id":"T3198","span":{"begin":198,"end":215},"obj":"CHEBI:16240"},{"id":"T3199","span":{"begin":292,"end":302},"obj":"GO:0008152"},{"id":"T3200","span":{"begin":307,"end":316},"obj":"MOP:0000568"}],"text":" Moreover, compared to wild-type or heterozygous cells, homozygous CbCln3Δex7/8 cells had significantly reduced cellular ATP levels (1.3 fold less, Fig. 8b) and exhibited reduced survival following hydrogen peroxide treatment (~50% of wild-type survival, Fig. 8c), suggesting impaired energy metabolism and oxidative stress response."}
craft-sa-dev
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Moreover, compared to wild-type or heterozygous cells, homozygous CbCln3Δex7/8 cells had significantly reduced cellular ATP levels (1.3 fold less, Fig. 8b) and exhibited reduced survival following hydrogen peroxide treatment (~50% of wild-type survival, Fig. 8c), suggesting impaired energy metabolism and oxidative stress response."}
craft-ca-core-ex-dev
{"project":"craft-ca-core-ex-dev","denotations":[{"id":"T3333","span":{"begin":23,"end":32},"obj":"SO_EXT:wild_type_entity_or_quality"},{"id":"T3334","span":{"begin":49,"end":54},"obj":"CL_GO_EXT:cell"},{"id":"T3335","span":{"begin":67,"end":69},"obj":"UBERON:0002037"},{"id":"T3336","span":{"begin":69,"end":73},"obj":"PR_EXT:000005591"},{"id":"T3337","span":{"begin":80,"end":85},"obj":"CL_GO_EXT:cell"},{"id":"T3338","span":{"begin":112,"end":120},"obj":"CL_GO_EXT:cell"},{"id":"T3339","span":{"begin":121,"end":124},"obj":"CHEBI_EXT:ATP"},{"id":"T3340","span":{"begin":198,"end":215},"obj":"CHEBI:16240"},{"id":"T3341","span":{"begin":235,"end":244},"obj":"SO_EXT:wild_type_entity_or_quality"},{"id":"T3342","span":{"begin":292,"end":302},"obj":"GO:0008152"},{"id":"T3343","span":{"begin":307,"end":316},"obj":"MOP:0000568"},{"id":"T3344","span":{"begin":324,"end":332},"obj":"GO_EXT:reaction_or_response"}],"text":" Moreover, compared to wild-type or heterozygous cells, homozygous CbCln3Δex7/8 cells had significantly reduced cellular ATP levels (1.3 fold less, Fig. 8b) and exhibited reduced survival following hydrogen peroxide treatment (~50% of wild-type survival, Fig. 8c), suggesting impaired energy metabolism and oxidative stress response."}