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PMC:539297 / 1680-4162 JSONTXT

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craft-ca-core-dev

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Id Subject Object Predicate Lexical cue
T535 364-368 SO:0000704 denotes gene
T536 387-392 SO:0000147 denotes exons
T537 417-425 SO:0000188 denotes intronic
T538 567-580 GO:0044754 denotes autolysosomes
T540 602-614,619-653 PR:000022190 denotes subunit c of mitochondrial ATP synthase complex
T541 619-653 GO:0005753 denotes mitochondrial ATP synthase complex
T542 710-713 UBERON:0001017 denotes CNS
T543 710-721 CL:0000117 denotes CNS neurons
T544 751-759 CL:0000540 denotes neuronal
T545 781-795 UBERON:0001016 denotes nervous system
T546 817-826 PR:000022190 denotes subunit c
T547 899-907 CL:0000540 denotes neuronal
T548 965-969 PR:000005591 denotes CLN3
T549 987-995 PR:000005591 denotes battenin
T550 1009-1013 PR:000005591 denotes CLN3
T551 1017-1023 PR:000005591 denotes cln3 p
T552 1061-1070 GO:0010467 denotes expressed
T553 1083-1091 GO:0016020 denotes membrane
T554 1126-1134 GO:0005764 denotes lysosome
T555 1145-1154 GO:0031982 denotes vesicular
T556 1175-1183 PR:000005591 denotes Battenin
T557 1239-1243 PR:Q9US09 denotes btn1
T558 1255-1259 PR:000005591 denotes CLN3
T559 1260-1268 SO:0000855 denotes ortholog
T560 1286-1294 PR:000005591 denotes battenin
T561 1298-1307 GO:0005764 denotes lysosomal
T562 1308-1322 GO:0006885 denotes pH homeostasis
T563 1327-1347 GO:0006865 denotes amino acid transport
T564 1390-1398 PR:000005591 denotes battenin
T565 1435-1446 SO:0000704 denotes genetically
T566 1460-1465 NCBITaxon:10088 denotes mouse
T567 1473-1477 PR:000005591 denotes Cln3
T568 1493-1497 NCBITaxon:10088 denotes mice
T569 1540-1547 GO:0010467 denotes express
T570 1571-1579 PR:000005591 denotes battenin
T571 1580-1587 SO:0001060 denotes isoform
T572 1612-1622 GO:0042571 denotes antibodies
T573 1667-1671 PR:000005591 denotes Cln3
T574 1687-1691 NCBITaxon:10088 denotes mice
T575 1738-1747 UBERON:0012101 denotes perinatal
T576 1742-1747 GO:0007567 denotes natal
T577 1757-1766 PR:000022190 denotes subunit c
T578 1816-1824 CL:0000540 denotes neuronal
T579 1947-1960 GO:0005739 denotes mitochondrial
T580 1947-1970 PR:000022190 denotes mitochondrial subunit c
T581 2013-2016 UBERON:0001017 denotes CNS
T582 2013-2024 CL:0000117 denotes CNS neurons
T583 2058-2071 CL:0000540 denotes neuronal cell
T584 2136-2156 GO:0008150 denotes biological processes
T585 2189-2199 UBERON:0002037 denotes cerebellar
T586 2189-2208 CL:1001611 denotes cerebellar neuronal
T587 2235-2239 PR:000005591 denotes Cln3
T588 2255-2259 NCBITaxon:10088 denotes mice
T589 2272-2274 UBERON:0002037 denotes Cb
T590 2274-2278 PR:000005591 denotes Cln3
T591 2354-2373 GO:0043227 denotes membrane organelles
T592 2383-2391 GO:0016020 denotes membrane
T593 2383-2403 GO:0055085 denotes membrane trafficking
T594 2416-2429 GO:0005739 denotes mitochondrial
T595 2463-2465 UBERON:0002037 denotes Cb
T529 20-28 CL:0000540 denotes neuronal
T530 208-217 GO:0050890 denotes cognitive
T531 237-242 GO:0016265 denotes death
T532 260-267 SO:0000704 denotes genetic
T533 331-338 SO:0001026 denotes genomic
T534 359-363 PR:000005591 denotes CLN3

craft-sa-dev

Id Subject Object Predicate Lexical cue
T696 11-19 JJ denotes Juvenile
T697 36-50 NN denotes lipofuscinosis
T698 20-28 JJ denotes neuronal
T699 29-35 NN denotes ceroid
T700 78-80 VBZ denotes is
T701 51-52 -LRB- denotes (
T702 52-56 NN denotes JNCL
T703 56-57 -RRB- denotes )
T704 57-59 , denotes ,
T705 59-61 CC denotes or
T706 62-68 NNP denotes Batten
T707 69-76 NN denotes disease
T708 76-78 , denotes ,
T709 81-82 DT denotes a
T710 139-147 NN denotes disorder
T711 83-94 RB denotes recessively
T712 95-104 VBN denotes inherited
T713 105-114 NN denotes childhood
T714 114-115 HYPH denotes -
T715 115-120 JJ denotes onset
T716 121-138 JJ denotes neurodegenerative
T717 148-161 VBN denotes characterized
T718 162-164 IN denotes by
T719 165-176 JJ denotes progressive
T720 177-186 NN denotes blindness
T721 186-188 , denotes ,
T722 188-196 NNS denotes seizures
T723 196-198 , denotes ,
T724 198-203 NN denotes motor
T725 218-225 NN denotes decline
T726 204-207 CC denotes and
T727 208-217 JJ denotes cognitive
T728 225-227 , denotes ,
T729 227-230 CC denotes and
T730 231-236 JJ denotes early
T731 237-242 NN denotes death
T732 243-244 -LRB- denotes [
T733 244-245 CD denotes 1
T734 245-246 -RRB- denotes ]
T735 246-247 . denotes .
T736 247-479 sentence denotes The primary genetic defect (>80% disease chromosomes) leading to JNCL is a 1.02 kb genomic DNA deletion in the CLN3 gene, which eliminates exons 7 and 8 and surrounding intronic DNA, predicting a non-functional protein product [2].
T737 248-251 DT denotes The
T738 268-274 NN denotes defect
T739 252-259 JJ denotes primary
T740 260-267 JJ denotes genetic
T741 318-320 VBZ denotes is
T742 275-276 -LRB- denotes (
T743 289-300 NNS denotes chromosomes
T744 276-277 SYM denotes >
T745 277-279 CD denotes 80
T746 279-280 NN denotes %
T747 281-288 NN denotes disease
T748 300-301 -RRB- denotes )
T749 302-309 VBG denotes leading
T750 310-312 IN denotes to
T751 313-317 NN denotes JNCL
T752 321-322 DT denotes a
T753 343-351 NN denotes deletion
T754 323-327 CD denotes 1.02
T755 328-330 NN denotes kb
T756 331-338 JJ denotes genomic
T757 339-342 NN denotes DNA
T758 352-354 IN denotes in
T759 355-358 DT denotes the
T760 364-368 NN denotes gene
T761 359-363 NN denotes CLN3
T762 368-370 , denotes ,
T763 370-375 WDT denotes which
T764 376-386 VBZ denotes eliminates
T765 387-392 NNS denotes exons
T766 393-394 CD denotes 7
T767 395-398 CC denotes and
T768 399-400 CD denotes 8
T769 401-404 CC denotes and
T770 405-416 JJ denotes surrounding
T771 426-429 NN denotes DNA
T772 417-425 JJ denotes intronic
T773 429-431 , denotes ,
T774 431-441 VBG denotes predicting
T775 442-443 DT denotes a
T776 467-474 NN denotes product
T777 444-458 JJ denotes non-functional
T778 459-466 NN denotes protein
T779 475-476 -LRB- denotes [
T780 476-477 CD denotes 2
T781 477-478 -RRB- denotes ]
T782 478-479 . denotes .
T783 479-660 sentence denotes The pathological hallmark of JNCL is autofluorescent ceroid lipofuscin deposits within autolysosomes that are enriched in subunit c of the mitochondrial ATP synthase complex [3-5].
T784 480-483 DT denotes The
T785 497-505 NN denotes hallmark
T786 484-496 JJ denotes pathological
T787 514-516 VBZ denotes is
T788 506-508 IN denotes of
T789 509-513 NN denotes JNCL
T790 517-532 JJ denotes autofluorescent
T791 551-559 NNS denotes deposits
T792 533-539 NN denotes ceroid
T793 540-550 NN denotes lipofuscin
T794 560-566 IN denotes within
T795 567-580 NNS denotes autolysosomes
T796 581-585 WDT denotes that
T797 586-589 VBP denotes are
T798 590-598 JJ denotes enriched
T799 599-601 IN denotes in
T800 602-609 NN denotes subunit
T801 610-611 NN denotes c
T802 612-614 IN denotes of
T803 615-618 DT denotes the
T804 646-653 NN denotes complex
T805 619-632 JJ denotes mitochondrial
T806 637-645 NN denotes synthase
T807 633-636 NN denotes ATP
T808 654-655 -LRB- denotes [
T809 655-656 CD denotes 3
T810 656-657 SYM denotes -
T811 657-658 CD denotes 5
T812 658-659 -RRB- denotes ]
T813 659-660 . denotes .
T814 660-796 sentence denotes Remarkably, these deposits are not only found in CNS neurons but are also abundant in non-neuronal cells outside of the nervous system.
T815 661-671 RB denotes Remarkably
T816 701-706 VBN denotes found
T817 671-673 , denotes ,
T818 673-678 DT denotes these
T819 679-687 NNS denotes deposits
T820 688-691 VBP denotes are
T821 692-695 RB denotes not
T822 696-700 RB denotes only
T823 707-709 IN denotes in
T824 710-713 NN denotes CNS
T825 714-721 NNS denotes neurons
T826 722-725 CC denotes but
T827 726-729 VBP denotes are
T828 730-734 RB denotes also
T829 735-743 JJ denotes abundant
T830 744-746 IN denotes in
T831 747-759 JJ denotes non-neuronal
T832 760-765 NNS denotes cells
T833 766-773 IN denotes outside
T834 774-776 IN denotes of
T835 777-780 DT denotes the
T836 789-795 NN denotes system
T837 781-788 JJ denotes nervous
T838 795-796 . denotes .
T839 796-960 sentence denotes The relationship of subunit c deposits to the JNCL disease process, and the underlying reason for the neuronal specificity of the disease remain poorly understood.
T840 797-800 DT denotes The
T841 801-813 NN denotes relationship
T842 935-941 VBP denotes remain
T843 814-816 IN denotes of
T844 817-824 NN denotes subunit
T845 825-826 NN denotes c
T846 827-835 NNS denotes deposits
T847 836-838 IN denotes to
T848 839-842 DT denotes the
T849 856-863 NN denotes process
T850 843-847 NN denotes JNCL
T851 848-855 NN denotes disease
T852 863-865 , denotes ,
T853 865-868 CC denotes and
T854 869-872 DT denotes the
T855 884-890 NN denotes reason
T856 873-883 JJ denotes underlying
T857 891-894 IN denotes for
T858 895-898 DT denotes the
T859 908-919 NN denotes specificity
T860 899-907 JJ denotes neuronal
T861 920-922 IN denotes of
T862 923-926 DT denotes the
T863 927-934 NN denotes disease
T864 942-948 RB denotes poorly
T865 949-959 VBN denotes understood
T866 959-960 . denotes .
T867 960-1174 sentence denotes The CLN3-encoded protein (battenin, also called CLN3 or cln3 p) is a highly conserved, ubiquitously expressed, multi-pass membrane protein [6] that localizes to the lysosome and other vesicular compartments [7-9].
T868 961-964 DT denotes The
T869 978-985 NN denotes protein
T870 965-969 NN denotes CLN3
T871 970-977 VBN denotes encoded
T872 969-970 HYPH denotes -
T873 1025-1027 VBZ denotes is
T874 986-987 -LRB- denotes (
T875 987-995 NN denotes battenin
T876 995-997 , denotes ,
T877 997-1001 RB denotes also
T878 1002-1008 VBN denotes called
T879 1009-1013 NN denotes CLN3
T880 1014-1016 CC denotes or
T881 1017-1021 NN denotes cln3
T882 1022-1023 NN denotes p
T883 1023-1024 -RRB- denotes )
T884 1028-1029 DT denotes a
T885 1092-1099 NN denotes protein
T886 1030-1036 RB denotes highly
T887 1037-1046 JJ denotes conserved
T888 1046-1048 , denotes ,
T889 1048-1060 RB denotes ubiquitously
T890 1061-1070 VBN denotes expressed
T891 1070-1072 , denotes ,
T892 1072-1082 NN denotes multi-pass
T893 1083-1091 NN denotes membrane
T894 1100-1101 -LRB- denotes [
T895 1101-1102 CD denotes 6
T896 1102-1103 -RRB- denotes ]
T897 1104-1108 WDT denotes that
T898 1109-1118 VBZ denotes localizes
T899 1119-1121 IN denotes to
T900 1122-1125 DT denotes the
T901 1126-1134 NN denotes lysosome
T902 1135-1138 CC denotes and
T903 1139-1144 JJ denotes other
T904 1155-1167 NNS denotes compartments
T905 1145-1154 JJ denotes vesicular
T906 1168-1169 -LRB- denotes [
T907 1169-1170 CD denotes 7
T908 1170-1171 SYM denotes -
T909 1171-1172 CD denotes 9
T910 1172-1173 -RRB- denotes ]
T911 1173-1174 . denotes .
T912 1174-1356 sentence denotes Battenin function remains to be elucidated, although studies of btn1, the yeast CLN3 ortholog, have implicated battenin in lysosomal pH homeostasis and amino acid transport [10,11].
T913 1175-1183 NN denotes Battenin
T914 1184-1192 NN denotes function
T915 1193-1200 VBZ denotes remains
T916 1201-1203 TO denotes to
T917 1207-1217 VBN denotes elucidated
T918 1204-1206 VB denotes be
T919 1217-1219 , denotes ,
T920 1219-1227 IN denotes although
T921 1275-1285 VBN denotes implicated
T922 1228-1235 NNS denotes studies
T923 1236-1238 IN denotes of
T924 1239-1243 NN denotes btn1
T925 1243-1245 , denotes ,
T926 1245-1248 DT denotes the
T927 1260-1268 NN denotes ortholog
T928 1249-1254 NN denotes yeast
T929 1255-1259 NN denotes CLN3
T930 1268-1270 , denotes ,
T931 1270-1274 VBP denotes have
T932 1286-1294 NN denotes battenin
T933 1295-1297 IN denotes in
T934 1298-1307 JJ denotes lysosomal
T935 1311-1322 NN denotes homeostasis
T936 1308-1310 NN denotes pH
T937 1323-1326 CC denotes and
T938 1327-1332 NN denotes amino
T939 1333-1337 NN denotes acid
T940 1338-1347 NN denotes transport
T941 1348-1349 -LRB- denotes [
T942 1352-1354 CD denotes 11
T943 1349-1351 CD denotes 10
T944 1351-1352 , denotes ,
T945 1354-1355 -RRB- denotes ]
T946 1355-1356 . denotes .
T947 1356-1472 sentence denotes To explore JNCL pathogenesis and battenin function, we previously generated a genetically precise JNCL mouse model.
T948 1357-1359 TO denotes To
T949 1360-1367 VB denotes explore
T950 1423-1432 VBD denotes generated
T951 1368-1372 NN denotes JNCL
T952 1373-1385 NN denotes pathogenesis
T953 1386-1389 CC denotes and
T954 1390-1398 NN denotes battenin
T955 1399-1407 NN denotes function
T956 1407-1409 , denotes ,
T957 1409-1411 PRP denotes we
T958 1412-1422 RB denotes previously
T959 1433-1434 DT denotes a
T960 1466-1471 NN denotes model
T961 1435-1446 RB denotes genetically
T962 1447-1454 JJ denotes precise
T963 1455-1459 NN denotes JNCL
T964 1460-1465 NN denotes mouse
T965 1471-1472 . denotes .
T966 1472-1655 sentence denotes Cln3Δex7/8 knock-in mice harbor the ~1 kb common JNCL mutation and express a non-truncated mutant battenin isoform that is detectable with antibodies recognizing C-terminal epitopes.
T967 1473-1481 NN denotes Cln3Δex7
T968 1493-1497 NNS denotes mice
T969 1481-1482 HYPH denotes /
T970 1482-1483 CD denotes 8
T971 1484-1489 VB denotes knock
T972 1489-1490 HYPH denotes -
T973 1490-1492 RP denotes in
T974 1498-1504 VBP denotes harbor
T975 1505-1508 DT denotes the
T976 1527-1535 NN denotes mutation
T977 1509-1510 SYM denotes ~
T978 1510-1511 CD denotes 1
T979 1512-1514 NN denotes kb
T980 1515-1521 JJ denotes common
T981 1522-1526 NN denotes JNCL
T982 1536-1539 CC denotes and
T983 1540-1547 VBP denotes express
T984 1548-1549 DT denotes a
T985 1580-1587 NN denotes isoform
T986 1550-1563 JJ denotes non-truncated
T987 1564-1570 NN denotes mutant
T988 1571-1579 NN denotes battenin
T989 1588-1592 WDT denotes that
T990 1593-1595 VBZ denotes is
T991 1596-1606 JJ denotes detectable
T992 1607-1611 IN denotes with
T993 1612-1622 NNS denotes antibodies
T994 1623-1634 VBG denotes recognizing
T995 1635-1636 NN denotes C
T996 1637-1645 JJ denotes terminal
T997 1636-1637 HYPH denotes -
T998 1646-1654 NNS denotes epitopes
T999 1654-1655 . denotes .
T1000 1655-1866 sentence denotes Homozygous Cln3Δex7/8 knock-in mice exhibit a progressive JNCL-like disease, with perinatal onset of subunit c deposition in many cell types and later onset of neuronal dysfunction and behavioral deficits [12].
T1001 1656-1666 JJ denotes Homozygous
T1002 1687-1691 NNS denotes mice
T1003 1667-1675 NN denotes Cln3Δex7
T1004 1675-1676 HYPH denotes /
T1005 1676-1677 CD denotes 8
T1006 1678-1683 VB denotes knock
T1007 1683-1684 HYPH denotes -
T1008 1684-1686 RP denotes in
T1009 1692-1699 VBP denotes exhibit
T1010 1700-1701 DT denotes a
T1011 1724-1731 NN denotes disease
T1012 1702-1713 JJ denotes progressive
T1013 1714-1718 NN denotes JNCL
T1014 1719-1723 JJ denotes like
T1015 1718-1719 HYPH denotes -
T1016 1731-1733 , denotes ,
T1017 1733-1737 IN denotes with
T1018 1738-1747 JJ denotes perinatal
T1019 1748-1753 NN denotes onset
T1020 1754-1756 IN denotes of
T1021 1757-1764 NN denotes subunit
T1022 1765-1766 NN denotes c
T1023 1767-1777 NN denotes deposition
T1024 1778-1780 IN denotes in
T1025 1781-1785 JJ denotes many
T1026 1791-1796 NNS denotes types
T1027 1786-1790 NN denotes cell
T1028 1797-1800 CC denotes and
T1029 1801-1806 JJ denotes later
T1030 1807-1812 NN denotes onset
T1031 1813-1815 IN denotes of
T1032 1816-1824 JJ denotes neuronal
T1033 1825-1836 NN denotes dysfunction
T1034 1837-1840 CC denotes and
T1035 1841-1851 JJ denotes behavioral
T1061 1977-1983 NN denotes manner
T1036 1852-1860 NNS denotes deficits
T1037 1861-1862 -LRB- denotes [
T1038 1862-1864 CD denotes 12
T1039 1864-1865 -RRB- denotes ]
T1040 1865-1866 . denotes .
T1041 1866-2025 sentence denotes These findings suggest that the major JNCL defect leads to abnormal turnover of mitochondrial subunit c, in a manner that selectively compromises CNS neurons.
T1042 1867-1872 DT denotes These
T1043 1873-1881 NNS denotes findings
T1044 1882-1889 VBP denotes suggest
T1045 1890-1894 IN denotes that
T1046 1917-1922 VBZ denotes leads
T1047 1895-1898 DT denotes the
T1048 1910-1916 NN denotes defect
T1049 1899-1904 JJ denotes major
T1050 1905-1909 NN denotes JNCL
T1051 1923-1925 IN denotes to
T1052 1926-1934 JJ denotes abnormal
T1053 1935-1943 NN denotes turnover
T1054 1944-1946 IN denotes of
T1055 1947-1960 JJ denotes mitochondrial
T1056 1969-1970 NN denotes c
T1057 1961-1968 NN denotes subunit
T1058 1970-1972 , denotes ,
T1059 1972-1974 IN denotes in
T1060 1975-1976 DT denotes a
T1062 1984-1988 WDT denotes that
T1063 2001-2012 VBZ denotes compromises
T1064 1989-2000 RB denotes selectively
T1065 2013-2016 NN denotes CNS
T1066 2017-2024 NNS denotes neurons
T1067 2024-2025 . denotes .
T1068 2025-2157 sentence denotes Currently, there is no suitable neuronal cell system to investigate the impact of the common JNCL mutation on biological processes.
T1069 2026-2035 RB denotes Currently
T1070 2043-2045 VBZ denotes is
T1071 2035-2037 , denotes ,
T1072 2037-2042 EX denotes there
T1073 2046-2048 DT denotes no
T1074 2072-2078 NN denotes system
T1075 2049-2057 JJ denotes suitable
T1076 2058-2066 JJ denotes neuronal
T1077 2067-2071 NN denotes cell
T1078 2079-2081 TO denotes to
T1079 2082-2093 VB denotes investigate
T1080 2094-2097 DT denotes the
T1081 2098-2104 NN denotes impact
T1082 2105-2107 IN denotes of
T1083 2108-2111 DT denotes the
T1084 2124-2132 NN denotes mutation
T1085 2112-2118 JJ denotes common
T1086 2119-2123 NN denotes JNCL
T1087 2133-2135 IN denotes on
T1088 2136-2146 JJ denotes biological
T1089 2147-2156 NNS denotes processes
T1090 2156-2157 . denotes .
T1091 2157-2260 sentence denotes Therefore, we have established cerebellar neuronal precursor cell lines from Cln3Δex7/8 knock-in mice.
T1092 2158-2167 RB denotes Therefore
T1093 2177-2188 VBN denotes established
T1094 2167-2169 , denotes ,
T1095 2169-2171 PRP denotes we
T1096 2172-2176 VBP denotes have
T1097 2189-2199 JJ denotes cerebellar
T1098 2224-2229 NNS denotes lines
T1099 2200-2208 JJ denotes neuronal
T1100 2209-2218 NN denotes precursor
T1101 2219-2223 NN denotes cell
T1102 2230-2234 IN denotes from
T1103 2235-2243 NN denotes Cln3Δex7
T1104 2255-2259 NNS denotes mice
T1105 2243-2244 HYPH denotes /
T1106 2244-2245 CD denotes 8
T1107 2246-2251 VB denotes knock
T1108 2251-2252 HYPH denotes -
T1109 2252-2254 RP denotes in
T1110 2259-2260 . denotes .
T1111 2260-2482 sentence denotes Homozygous CbCln3Δex7/8 cells exhibit pathological hallmarks of the disease, and a survey of membrane organelles revealed membrane trafficking defects and mitochondrial dysfunction in homozygous mutant CbCln3Δex7/8 cells.
T1112 2261-2271 JJ denotes Homozygous
T1113 2285-2290 NNS denotes cells
T1114 2272-2282 NN denotes CbCln3Δex7
T1115 2282-2283 HYPH denotes /
T1116 2283-2284 CD denotes 8
T1117 2291-2298 VBP denotes exhibit
T1118 2299-2311 JJ denotes pathological
T1119 2312-2321 NNS denotes hallmarks
T1120 2322-2324 IN denotes of
T1121 2325-2328 DT denotes the
T1122 2329-2336 NN denotes disease
T1123 2336-2338 , denotes ,
T1124 2338-2341 CC denotes and
T1125 2342-2343 DT denotes a
T1126 2344-2350 NN denotes survey
T1127 2374-2382 VBD denotes revealed
T1128 2351-2353 IN denotes of
T1129 2354-2362 NN denotes membrane
T1130 2363-2373 NNS denotes organelles
T1131 2383-2391 NN denotes membrane
T1132 2392-2403 VBG denotes trafficking
T1133 2404-2411 NNS denotes defects
T1134 2412-2415 CC denotes and
T1135 2416-2429 JJ denotes mitochondrial
T1136 2430-2441 NN denotes dysfunction
T1137 2442-2444 IN denotes in
T1138 2445-2455 JJ denotes homozygous
T1139 2456-2462 NN denotes mutant
T1140 2476-2481 NNS denotes cells
T1141 2463-2473 NN denotes CbCln3Δex7
T1142 2473-2474 HYPH denotes /
T1143 2474-2475 CD denotes 8
T1144 2481-2482 . denotes .
R266 T696 T697 amod Juvenile,lipofuscinosis
R267 T697 T700 nsubj lipofuscinosis,is
R268 T698 T697 amod neuronal,lipofuscinosis
R269 T699 T697 compound ceroid,lipofuscinosis
R270 T701 T697 punct (,lipofuscinosis
R271 T702 T697 appos JNCL,lipofuscinosis
R272 T703 T697 punct ),lipofuscinosis
R273 T704 T697 punct ", ",lipofuscinosis
R274 T705 T697 cc or,lipofuscinosis
R275 T706 T707 compound Batten,disease
R276 T707 T697 conj disease,lipofuscinosis
R277 T708 T700 punct ", ",is
R278 T709 T710 det a,disorder
R279 T710 T700 attr disorder,is
R280 T711 T712 advmod recessively,inherited
R281 T712 T710 amod inherited,disorder
R282 T713 T710 nmod childhood,disorder
R283 T714 T713 punct -,childhood
R284 T715 T713 amod onset,childhood
R285 T716 T710 amod neurodegenerative,disorder
R286 T717 T710 acl characterized,disorder
R287 T718 T717 agent by,characterized
R288 T719 T720 amod progressive,blindness
R289 T720 T718 pobj blindness,by
R290 T721 T720 punct ", ",blindness
R291 T722 T720 conj seizures,blindness
R292 T723 T722 punct ", ",seizures
R293 T724 T725 nmod motor,decline
R294 T725 T722 conj decline,seizures
R295 T726 T724 cc and,motor
R296 T727 T724 conj cognitive,motor
R297 T728 T725 punct ", ",decline
R298 T729 T725 cc and,decline
R299 T730 T731 amod early,death
R300 T731 T725 conj death,decline
R301 T732 T733 punct [,1
R302 T733 T717 parataxis 1,characterized
R303 T734 T733 punct ],1
R304 T735 T700 punct .,is
R305 T737 T738 det The,defect
R306 T738 T741 nsubj defect,is
R307 T739 T738 amod primary,defect
R308 T740 T738 amod genetic,defect
R309 T742 T743 punct (,chromosomes
R311 T744 T745 punct >,80
R312 T745 T746 nummod 80,%
R313 T746 T743 compound %,chromosomes
R314 T747 T743 compound disease,chromosomes
R315 T748 T743 punct ),chromosomes
R316 T749 T738 acl leading,defect
R317 T750 T749 prep to,leading
R318 T751 T750 pobj JNCL,to
R319 T752 T753 det a,deletion
R321 T754 T755 nummod 1.02,kb
R322 T755 T753 nmod kb,deletion
R323 T756 T753 amod genomic,deletion
R324 T757 T753 compound DNA,deletion
R325 T758 T753 prep in,deletion
R326 T759 T760 det the,gene
R327 T760 T758 pobj gene,in
R328 T761 T760 compound CLN3,gene
R329 T762 T753 punct ", ",deletion
R330 T763 T764 dep which,eliminates
R331 T764 T753 relcl eliminates,deletion
R332 T765 T766 nmod exons,7
R333 T766 T764 dobj 7,eliminates
R334 T767 T766 cc and,7
R335 T768 T766 conj 8,7
R336 T769 T766 cc and,7
R337 T770 T771 amod surrounding,DNA
R338 T771 T766 conj DNA,7
R339 T772 T771 amod intronic,DNA
R340 T773 T741 punct ", ",is
R341 T774 T741 advcl predicting,is
R342 T775 T776 det a,product
R343 T776 T774 dobj product,predicting
R344 T777 T776 amod non-functional,product
R345 T778 T776 compound protein,product
R346 T779 T780 punct [,2
R347 T780 T741 parataxis 2,is
R348 T781 T780 punct ],2
R349 T782 T741 punct .,is
R350 T784 T785 det The,hallmark
R351 T785 T787 nsubj hallmark,is
R352 T786 T785 amod pathological,hallmark
R353 T788 T785 prep of,hallmark
R354 T789 T788 pobj JNCL,of
R355 T790 T791 amod autofluorescent,deposits
R356 T791 T787 attr deposits,is
R357 T792 T791 compound ceroid,deposits
R358 T793 T791 compound lipofuscin,deposits
R359 T794 T791 prep within,deposits
R360 T795 T794 pobj autolysosomes,within
R361 T796 T797 dep that,are
R362 T797 T791 relcl are,deposits
R363 T798 T797 acomp enriched,are
R364 T799 T797 prep in,are
R365 T800 T801 compound subunit,c
R366 T801 T799 pobj c,in
R367 T802 T801 prep of,c
R368 T803 T804 det the,complex
R369 T804 T802 pobj complex,of
R370 T805 T806 amod mitochondrial,synthase
R371 T806 T804 compound synthase,complex
R372 T807 T806 compound ATP,synthase
R373 T808 T809 punct [,3
R374 T809 T787 parataxis 3,is
R375 T810 T811 punct -,5
R376 T811 T809 prep 5,3
R377 T812 T809 punct ],3
R378 T813 T787 punct .,is
R379 T815 T816 advmod Remarkably,found
R380 T817 T816 punct ", ",found
R381 T818 T819 det these,deposits
R382 T819 T816 nsubjpass deposits,found
R383 T820 T816 auxpass are,found
R384 T821 T816 preconj not,found
R385 T822 T821 advmod only,not
R386 T823 T816 prep in,found
R387 T824 T825 compound CNS,neurons
R388 T825 T823 pobj neurons,in
R389 T826 T816 cc but,found
R390 T827 T816 conj are,found
R391 T828 T827 advmod also,are
R392 T829 T827 acomp abundant,are
R393 T830 T827 prep in,are
R394 T831 T832 amod non-neuronal,cells
R395 T832 T830 pobj cells,in
R396 T833 T832 prep outside,cells
R397 T834 T833 prep of,outside
R398 T835 T836 det the,system
R399 T836 T834 pobj system,of
R400 T837 T836 amod nervous,system
R401 T838 T816 punct .,found
R402 T840 T841 det The,relationship
R403 T841 T842 nsubj relationship,remain
R404 T843 T841 prep of,relationship
R405 T844 T845 compound subunit,c
R406 T845 T846 compound c,deposits
R407 T846 T843 pobj deposits,of
R408 T847 T841 prep to,relationship
R409 T848 T849 det the,process
R410 T849 T847 pobj process,to
R411 T850 T851 compound JNCL,disease
R412 T851 T849 compound disease,process
R413 T852 T841 punct ", ",relationship
R414 T853 T841 cc and,relationship
R415 T854 T855 det the,reason
R416 T855 T841 conj reason,relationship
R417 T856 T855 amod underlying,reason
R418 T857 T855 prep for,reason
R419 T858 T859 det the,specificity
R420 T859 T857 pobj specificity,for
R421 T860 T859 amod neuronal,specificity
R422 T861 T859 prep of,specificity
R423 T862 T863 det the,disease
R424 T863 T861 pobj disease,of
R425 T864 T865 advmod poorly,understood
R426 T865 T842 acomp understood,remain
R427 T866 T842 punct .,remain
R428 T868 T869 det The,protein
R429 T869 T873 nsubj protein,is
R430 T870 T871 npadvmod CLN3,encoded
R431 T871 T869 amod encoded,protein
R432 T872 T871 punct -,encoded
R433 T874 T869 punct (,protein
R434 T875 T869 appos battenin,protein
R435 T876 T875 punct ", ",battenin
R436 T877 T878 advmod also,called
R437 T878 T875 acl called,battenin
R438 T879 T878 oprd CLN3,called
R439 T880 T879 cc or,CLN3
R440 T881 T882 compound cln3,p
R441 T882 T879 conj p,CLN3
R442 T883 T873 punct ),is
R443 T884 T885 det a,protein
R444 T885 T873 attr protein,is
R445 T886 T887 advmod highly,conserved
R446 T887 T885 amod conserved,protein
R447 T888 T885 punct ", ",protein
R448 T889 T890 advmod ubiquitously,expressed
R449 T890 T885 amod expressed,protein
R450 T891 T885 punct ", ",protein
R451 T892 T885 compound multi-pass,protein
R452 T893 T885 compound membrane,protein
R453 T894 T895 punct [,6
R454 T895 T885 parataxis 6,protein
R455 T896 T895 punct ],6
R456 T897 T898 dep that,localizes
R457 T898 T885 relcl localizes,protein
R458 T899 T898 prep to,localizes
R459 T900 T901 det the,lysosome
R460 T901 T899 pobj lysosome,to
R461 T902 T901 cc and,lysosome
R462 T903 T904 amod other,compartments
R463 T904 T901 conj compartments,lysosome
R464 T905 T904 amod vesicular,compartments
R465 T906 T907 punct [,7
R466 T907 T898 parataxis 7,localizes
R467 T908 T909 punct -,9
R468 T909 T907 prep 9,7
R469 T910 T907 punct ],7
R470 T911 T873 punct .,is
R471 T913 T914 compound Battenin,function
R472 T914 T915 nsubj function,remains
R473 T916 T917 aux to,elucidated
R474 T917 T915 xcomp elucidated,remains
R475 T918 T917 auxpass be,elucidated
R476 T919 T917 punct ", ",elucidated
R477 T920 T921 mark although,implicated
R478 T921 T917 advcl implicated,elucidated
R479 T922 T921 nsubj studies,implicated
R480 T923 T922 prep of,studies
R481 T924 T923 pobj btn1,of
R482 T925 T924 punct ", ",btn1
R483 T926 T927 det the,ortholog
R484 T927 T924 appos ortholog,btn1
R485 T928 T927 compound yeast,ortholog
R486 T929 T927 compound CLN3,ortholog
R487 T930 T921 punct ", ",implicated
R488 T931 T921 aux have,implicated
R489 T932 T921 dobj battenin,implicated
R490 T933 T921 prep in,implicated
R491 T934 T935 amod lysosomal,homeostasis
R492 T935 T933 pobj homeostasis,in
R493 T936 T935 compound pH,homeostasis
R494 T937 T935 cc and,homeostasis
R495 T938 T939 compound amino,acid
R496 T939 T940 compound acid,transport
R497 T940 T935 conj transport,homeostasis
R498 T941 T942 punct [,11
R499 T942 T921 parataxis 11,implicated
R500 T943 T942 nummod 10,11
R501 T944 T942 punct ",",11
R502 T945 T942 punct ],11
R503 T946 T915 punct .,remains
R504 T948 T949 aux To,explore
R505 T949 T950 advcl explore,generated
R506 T951 T952 compound JNCL,pathogenesis
R507 T952 T949 dobj pathogenesis,explore
R508 T953 T952 cc and,pathogenesis
R509 T954 T955 compound battenin,function
R510 T955 T952 conj function,pathogenesis
R511 T956 T950 punct ", ",generated
R512 T957 T950 nsubj we,generated
R513 T958 T950 advmod previously,generated
R514 T959 T960 det a,model
R516 T961 T962 advmod genetically,precise
R517 T962 T960 amod precise,model
R518 T963 T960 compound JNCL,model
R519 T964 T960 compound mouse,model
R520 T965 T950 punct .,generated
R521 T967 T968 nmod Cln3Δex7,mice
R522 T968 T974 nsubj mice,harbor
R523 T969 T967 punct /,Cln3Δex7
R524 T970 T967 nummod 8,Cln3Δex7
R525 T971 T968 amod knock,mice
R526 T972 T971 punct -,knock
R527 T973 T971 prt in,knock
R528 T975 T976 det the,mutation
R529 T976 T974 dobj mutation,harbor
R530 T977 T978 punct ~,1
R531 T978 T979 nummod 1,kb
R532 T979 T976 nmod kb,mutation
R533 T980 T976 amod common,mutation
R534 T981 T976 compound JNCL,mutation
R535 T982 T974 cc and,harbor
R536 T983 T974 conj express,harbor
R537 T984 T985 det a,isoform
R538 T985 T983 dobj isoform,express
R539 T986 T985 amod non-truncated,isoform
R540 T987 T988 compound mutant,battenin
R541 T988 T985 compound battenin,isoform
R542 T989 T990 dep that,is
R543 T990 T985 relcl is,isoform
R544 T991 T990 acomp detectable,is
R545 T992 T990 prep with,is
R546 T993 T992 pobj antibodies,with
R547 T994 T993 acl recognizing,antibodies
R548 T995 T996 npadvmod C,terminal
R549 T996 T998 amod terminal,epitopes
R550 T997 T996 punct -,terminal
R551 T998 T994 dobj epitopes,recognizing
R552 T999 T974 punct .,harbor
R553 T1001 T1002 amod Homozygous,mice
R554 T1002 T1009 nsubj mice,exhibit
R555 T1003 T1002 nmod Cln3Δex7,mice
R556 T1004 T1003 punct /,Cln3Δex7
R557 T1005 T1003 nummod 8,Cln3Δex7
R558 T1006 T1002 amod knock,mice
R559 T1007 T1006 punct -,knock
R560 T1008 T1006 prt in,knock
R561 T1010 T1011 det a,disease
R563 T1012 T1011 amod progressive,disease
R564 T1013 T1014 npadvmod JNCL,like
R565 T1014 T1011 amod like,disease
R566 T1015 T1014 punct -,like
R567 T1016 T1011 punct ", ",disease
R568 T1017 T1011 prep with,disease
R569 T1018 T1019 amod perinatal,onset
R570 T1019 T1017 pobj onset,with
R571 T1020 T1019 prep of,onset
R572 T1021 T1022 compound subunit,c
R573 T1022 T1023 compound c,deposition
R574 T1023 T1020 pobj deposition,of
R575 T1024 T1023 prep in,deposition
R576 T1025 T1026 amod many,types
R577 T1026 T1024 pobj types,in
R578 T1027 T1026 compound cell,types
R579 T1028 T1019 cc and,onset
R580 T1029 T1030 amod later,onset
R581 T1030 T1019 conj onset,onset
R582 T1031 T1030 prep of,onset
R583 T1032 T1033 amod neuronal,dysfunction
R584 T1033 T1031 pobj dysfunction,of
R585 T1034 T1033 cc and,dysfunction
R586 T1035 T1036 amod behavioral,deficits
R587 T1036 T1033 conj deficits,dysfunction
R588 T1037 T1038 punct [,12
R589 T1038 T1009 parataxis 12,exhibit
R590 T1039 T1038 punct ],12
R591 T1040 T1009 punct .,exhibit
R592 T1042 T1043 det These,findings
R593 T1043 T1044 nsubj findings,suggest
R594 T1045 T1046 mark that,leads
R596 T1047 T1048 det the,defect
R597 T1048 T1046 nsubj defect,leads
R598 T1049 T1048 amod major,defect
R599 T1050 T1048 compound JNCL,defect
R600 T1051 T1046 prep to,leads
R601 T1052 T1053 amod abnormal,turnover
R602 T1053 T1051 pobj turnover,to
R603 T1054 T1053 prep of,turnover
R604 T1055 T1056 amod mitochondrial,c
R605 T1056 T1054 pobj c,of
R606 T1057 T1056 compound subunit,c
R607 T1058 T1046 punct ", ",leads
R608 T1059 T1046 prep in,leads
R609 T1060 T1061 det a,manner
R610 T1061 T1059 pobj manner,in
R611 T1062 T1063 dep that,compromises
R612 T1063 T1061 relcl compromises,manner
R613 T1064 T1063 advmod selectively,compromises
R614 T1065 T1066 compound CNS,neurons
R615 T1066 T1063 dobj neurons,compromises
R616 T1067 T1044 punct .,suggest
R617 T1069 T1070 advmod Currently,is
R618 T1071 T1070 punct ", ",is
R619 T1072 T1070 expl there,is
R620 T1073 T1074 det no,system
R621 T1074 T1070 attr system,is
R622 T1075 T1074 amod suitable,system
R623 T1076 T1077 amod neuronal,cell
R624 T1077 T1074 compound cell,system
R625 T1078 T1079 aux to,investigate
R626 T1079 T1074 advcl investigate,system
R627 T1080 T1081 det the,impact
R628 T1081 T1079 dobj impact,investigate
R629 T1082 T1081 prep of,impact
R630 T1083 T1084 det the,mutation
R631 T1084 T1082 pobj mutation,of
R632 T1085 T1084 amod common,mutation
R633 T1086 T1084 compound JNCL,mutation
R634 T1087 T1081 prep on,impact
R635 T1088 T1089 amod biological,processes
R636 T1089 T1087 pobj processes,on
R637 T1090 T1070 punct .,is
R638 T1092 T1093 advmod Therefore,established
R639 T1094 T1093 punct ", ",established
R640 T1095 T1093 nsubj we,established
R641 T1096 T1093 aux have,established
R642 T1097 T1098 amod cerebellar,lines
R643 T1098 T1093 dobj lines,established
R644 T1099 T1098 amod neuronal,lines
R645 T1100 T1098 compound precursor,lines
R646 T1101 T1098 compound cell,lines
R647 T1102 T1093 prep from,established
R648 T1103 T1104 nmod Cln3Δex7,mice
R649 T1104 T1102 pobj mice,from
R650 T1105 T1103 punct /,Cln3Δex7
R651 T1106 T1103 nummod 8,Cln3Δex7
R652 T1107 T1104 amod knock,mice
R653 T1108 T1107 punct -,knock
R654 T1109 T1107 prt in,knock
R655 T1110 T1093 punct .,established
R656 T1112 T1113 amod Homozygous,cells
R657 T1113 T1117 nsubj cells,exhibit
R658 T1114 T1113 nmod CbCln3Δex7,cells
R659 T1115 T1114 punct /,CbCln3Δex7
R660 T1116 T1114 nummod 8,CbCln3Δex7
R661 T1118 T1119 amod pathological,hallmarks
R662 T1119 T1117 dobj hallmarks,exhibit
R663 T1120 T1119 prep of,hallmarks
R664 T1121 T1122 det the,disease
R665 T1122 T1120 pobj disease,of
R666 T1123 T1117 punct ", ",exhibit
R667 T1124 T1117 cc and,exhibit
R668 T1125 T1126 det a,survey
R669 T1126 T1127 nsubj survey,revealed
R670 T1127 T1117 conj revealed,exhibit
R671 T1128 T1126 prep of,survey
R672 T1129 T1130 compound membrane,organelles
R673 T1130 T1128 pobj organelles,of
R674 T1131 T1132 npadvmod membrane,trafficking
R675 T1132 T1133 amod trafficking,defects
R676 T1133 T1127 dobj defects,revealed
R677 T1134 T1133 cc and,defects
R678 T1135 T1136 amod mitochondrial,dysfunction
R679 T1136 T1133 conj dysfunction,defects
R680 T1137 T1127 prep in,revealed
R681 T1138 T1139 amod homozygous,mutant
R682 T1139 T1140 nmod mutant,cells
R683 T1140 T1137 pobj cells,in
R684 T1141 T1140 nmod CbCln3Δex7,cells
R685 T1142 T1141 punct /,CbCln3Δex7
R686 T1143 T1141 nummod 8,CbCln3Δex7
R687 T1144 T1127 punct .,revealed
R310 T743 T738 parataxis chromosomes,defect
R320 T753 T741 attr deletion,is
R515 T960 T950 dobj model,generated
R562 T1011 T1009 dobj disease,exhibit
R595 T1046 T1044 ccomp leads,suggest

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the bag model. You can change it to the chain model.

Id Subject Object Predicate Lexical cue
T619 710-713 UBERON:0001017 denotes CNS
T620 710-721 CL:0000117 denotes CNS neurons
T621 751-759 CL:0000540 denotes neuronal
T622 760-765 CL_GO_EXT:cell denotes cells
T623 781-795 UBERON:0001016 denotes nervous system
T624 817-826 PR_EXT:000022190 denotes subunit c
T625 899-907 CL:0000540 denotes neuronal
T626 965-969 PR_EXT:000005591 denotes CLN3
T627 970-977 SO_EXT:sequence_coding_function denotes encoded
T628 978-985 CHEBI_PR_EXT:protein denotes protein
T629 987-995 PR_EXT:000005591 denotes battenin
T630 1009-1013 PR_EXT:000005591 denotes CLN3
T631 1017-1023 PR_EXT:000005591 denotes cln3 p
T632 1037-1046 SO_EXT:biological_conservation_process_or_quality denotes conserved
T633 1061-1070 GO:0010467 denotes expressed
T634 1083-1091 GO:0016020 denotes membrane
T635 1092-1099 CHEBI_PR_EXT:protein denotes protein
T636 1109-1118 GO_PATO_EXT:biological_localization_process_or_quality denotes localizes
T637 1126-1134 GO:0005764 denotes lysosome
T638 1145-1154 GO:0031982 denotes vesicular
T639 1175-1183 PR_EXT:000005591 denotes Battenin
T640 1239-1243 PR_EXT:Q9US09 denotes btn1
T641 1249-1254 NCBITaxon_EXT:yeast denotes yeast
T642 1255-1259 PR_EXT:000005591 denotes CLN3
T643 1260-1268 SO_EXT:0000855 denotes ortholog
T644 1286-1294 PR_EXT:000005591 denotes battenin
T645 1298-1307 GO:0005764 denotes lysosomal
T646 1308-1322 GO:0006885 denotes pH homeostasis
T647 1327-1337 CHEBI_SO_EXT:amino_acid denotes amino acid
T648 1327-1347 GO:0006865 denotes amino acid transport
T649 1390-1398 PR_EXT:000005591 denotes battenin
T650 1435-1446 SO_EXT:0000704 denotes genetically
T651 1460-1465 NCBITaxon:10088 denotes mouse
T652 1473-1477 PR_EXT:000005591 denotes Cln3
T653 1493-1497 NCBITaxon:10088 denotes mice
T654 1513-1514 CHEBI_SO_EXT:base denotes b
T655 1527-1535 SO_EXT:sequence_alteration_entity_or_process denotes mutation
T656 1540-1547 GO:0010467 denotes express
T657 1554-1563 SO_EXT:sequence_truncation_process denotes truncated
T658 1564-1570 SO_EXT:sequence_altered_entity_or_alteration_process denotes mutant
T659 1571-1579 PR_EXT:000005591 denotes battenin
T660 1580-1587 SO_EXT:0001060 denotes isoform
T661 1612-1622 GO:0042571 denotes antibodies
T662 1635-1645 CHEBI_SO_EXT:C_terminus_or_C_terminal_region denotes C-terminal
T663 1646-1654 CHEBI_SO_EXT:epitope denotes epitopes
T664 1667-1671 PR_EXT:000005591 denotes Cln3
T665 1687-1691 NCBITaxon:10088 denotes mice
T666 1738-1747 UBERON:0012101 denotes perinatal
T667 1742-1747 GO:0007567 denotes natal
T668 1757-1766 PR_EXT:000022190 denotes subunit c
T669 1786-1790 CL_GO_EXT:cell denotes cell
T670 1816-1824 CL:0000540 denotes neuronal
T671 1841-1851 GO_PATO_EXT:biological_behavior denotes behavioral
T672 1947-1960 GO:0005739 denotes mitochondrial
T673 1947-1970 PR_EXT:000022190 denotes mitochondrial subunit c
T674 2013-2016 UBERON:0001017 denotes CNS
T675 2013-2024 CL:0000117 denotes CNS neurons
T676 2058-2071 CL:0000540 denotes neuronal cell
T677 2067-2071 CL_GO_EXT:cell denotes cell
T678 2124-2132 SO_EXT:sequence_alteration_entity_or_process denotes mutation
T679 2136-2146 CHEBI_GO_EXT:biological_process_or_quality_or_role denotes biological
T680 2136-2156 GO:0008150 denotes biological processes
T681 2189-2199 UBERON:0002037 denotes cerebellar
T682 2189-2208 CL:1001611 denotes cerebellar neuronal
T683 2219-2223 CL_GO_EXT:cell denotes cell
T684 2235-2239 PR_EXT:000005591 denotes Cln3
T685 2255-2259 NCBITaxon:10088 denotes mice
T686 2272-2274 UBERON:0002037 denotes Cb
T687 2274-2278 PR_EXT:000005591 denotes Cln3
T688 2285-2290 CL_GO_EXT:cell denotes cells
T689 2354-2373 GO:0043227 denotes membrane organelles
T690 2383-2391 GO:0016020 denotes membrane
T691 2383-2403 GO:0055085 denotes membrane trafficking
T692 2416-2429 GO:0005739 denotes mitochondrial
T693 2456-2462 SO_EXT:sequence_altered_entity_or_alteration_process denotes mutant
T694 2463-2465 UBERON:0002037 denotes Cb
T695 2476-2481 CL_GO_EXT:cell denotes cells
T596 11-19 PATO_UBERON_EXT:juvenile_organism denotes Juvenile
T597 20-28 CL:0000540 denotes neuronal
T598 105-114 UBERON_EXT:childhood denotes childhood
T599 198-203 GO_EXT:biological_movement_or_translocation_process denotes motor
T600 208-217 GO:0050890 denotes cognitive
T601 237-242 GO:0016265 denotes death
T602 260-267 SO_EXT:0000704 denotes genetic
T603 289-300 GO_SO_EXT:chromosome denotes chromosomes
T604 329-330 CHEBI_SO_EXT:base denotes b
T605 331-342 SO_EXT:genomic_DNA denotes genomic DNA
T606 339-342 CHEBI_SO_EXT:DNA denotes DNA
T607 343-351 SO_EXT:sequence_deletion_entity_or_process denotes deletion
T608 359-363 PR_EXT:000005591 denotes CLN3
T609 364-368 SO_EXT:0000704 denotes gene
T610 387-392 SO_EXT:0000147 denotes exons
T611 417-425 SO_EXT:0000188 denotes intronic
T612 426-429 CHEBI_SO_EXT:DNA denotes DNA
T613 459-466 CHEBI_PR_EXT:protein denotes protein
T614 567-580 GO:0044754 denotes autolysosomes
T616 602-614,619-653 PR_EXT:000022190 denotes subunit c of mitochondrial ATP synthase complex
T617 619-653 GO:0005753 denotes mitochondrial ATP synthase complex
T618 633-636 CHEBI_EXT:ATP denotes ATP

2_test

Id Subject Object Predicate Lexical cue
15588329-3146319-12950135 244-245 3146319 denotes 1
15588329-7553855-12950136 476-477 7553855 denotes 2
15588329-1535180-12950137 655-656 1535180 denotes 3
15588329-1535179-12950137 655-656 1535179 denotes 3
15588329-3146325-12950137 655-656 3146325 denotes 3
15588329-12706816-12950138 1101-1102 12706816 denotes 6
15588329-14622109-12950139 1169-1170 14622109 denotes 7
15588329-11590129-12950139 1169-1170 11590129 denotes 7
15588329-14699076-12950139 1169-1170 14699076 denotes 7
15588329-10319861-12950140 1349-1351 10319861 denotes 10
15588329-14660799-12950141 1352-1354 14660799 denotes 11
15588329-12374761-12950142 1862-1864 12374761 denotes 12