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PMC:539297 / 162-580 JSONTXT

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craft-ca-core-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T65 118-122 PR:000005591 denotes CLN3
T66 155-163 PR:000005591 denotes battenin
T67 196-209 GO:0005739 denotes mitochondrial
T68 196-233 PR:000022190 denotes mitochondrial ATP synthase, subunit c
T69 257-260 UBERON:0001017 denotes CNS
T70 257-268 CL:0000117 denotes CNS neurons
T71 294-298 PR:000005591 denotes Cln3
T72 314-318 NCBITaxon:10088 denotes mice
T73 362-369 GO:0010467 denotes express
T74 377-385 PR:000005591 denotes battenin

craft-sa-dev

Id Subject Object Predicate Lexical cue
T191 0-10 sentence denotes Background
T192 0-10 NN denotes Background
T193 10-132 sentence denotes JNCL is a recessively inherited, childhood-onset neurodegenerative disease most-commonly caused by a ~1 kb CLN3 mutation.
T194 11-15 NN denotes JNCL
T195 16-18 VBZ denotes is
T196 19-20 DT denotes a
T197 78-85 NN denotes disease
T198 21-32 RB denotes recessively
T199 33-42 VBN denotes inherited
T200 42-44 , denotes ,
T201 44-53 NN denotes childhood
T202 54-59 NN denotes onset
T203 53-54 HYPH denotes -
T204 60-77 JJ denotes neurodegenerative
T205 86-90 RBS denotes most
T206 91-99 RB denotes commonly
T207 90-91 HYPH denotes -
T208 100-106 VBN denotes caused
T209 107-109 IN denotes by
T210 110-111 DT denotes a
T211 123-131 NN denotes mutation
T212 112-113 SYM denotes ~
T213 113-114 CD denotes 1
T214 115-117 NN denotes kb
T215 118-122 NN denotes CLN3
T216 131-132 . denotes .
T217 132-269 sentence denotes The resulting loss of battenin activity leads to deposition of mitochondrial ATP synthase, subunit c and a specific loss of CNS neurons.
T218 133-136 DT denotes The
T219 147-151 NN denotes loss
T220 137-146 JJ denotes resulting
T221 173-178 VBZ denotes leads
T222 152-154 IN denotes of
T223 155-163 NN denotes battenin
T224 164-172 NN denotes activity
T225 179-181 IN denotes to
T226 182-192 NN denotes deposition
T227 193-195 IN denotes of
T228 196-209 JJ denotes mitochondrial
T229 214-222 NN denotes synthase
T230 210-213 NN denotes ATP
T231 222-224 , denotes ,
T232 224-231 NN denotes subunit
T233 232-233 NN denotes c
T234 234-237 CC denotes and
T235 238-239 DT denotes a
T236 249-253 NN denotes loss
T237 240-248 JJ denotes specific
T238 254-256 IN denotes of
T239 257-260 NN denotes CNS
T240 261-268 NNS denotes neurons
T241 268-269 . denotes .
T242 269-418 sentence denotes We previously generated Cln3Δex7/8 knock-in mice, which replicate the common JNCL mutation, express mutant battenin and display JNCL-like pathology.
T243 270-272 PRP denotes We
T244 284-293 VBD denotes generated
T245 273-283 RB denotes previously
T246 294-302 NN denotes Cln3Δex7
T247 314-318 NNS denotes mice
T248 302-303 HYPH denotes /
T249 303-304 CD denotes 8
T250 305-310 VB denotes knock
T251 310-311 HYPH denotes -
T252 311-313 RP denotes in
T253 318-320 , denotes ,
T254 320-325 WDT denotes which
T255 326-335 VBP denotes replicate
T256 336-339 DT denotes the
T257 352-360 NN denotes mutation
T258 340-346 JJ denotes common
T259 347-351 NN denotes JNCL
T260 360-362 , denotes ,
T261 362-369 VBP denotes express
T262 370-376 NN denotes mutant
T263 377-385 NN denotes battenin
T264 386-389 CC denotes and
T265 390-397 VBP denotes display
T266 398-402 NN denotes JNCL
T267 403-407 JJ denotes like
T268 402-403 HYPH denotes -
T269 408-417 NN denotes pathology
T270 417-418 . denotes .
R85 T264 T261 cc and,express
R86 T265 T261 conj display,express
R84 T263 T261 dobj battenin,express
R20 T194 T195 nsubj JNCL,is
R21 T196 T197 det a,disease
R22 T197 T195 attr disease,is
R23 T198 T199 advmod recessively,inherited
R24 T199 T197 amod inherited,disease
R25 T200 T197 punct ", ",disease
R26 T201 T202 nmod childhood,onset
R27 T202 T197 nmod onset,disease
R28 T203 T202 punct -,onset
R29 T204 T197 amod neurodegenerative,disease
R30 T205 T206 advmod most,commonly
R32 T207 T206 punct -,commonly
R33 T208 T197 acl caused,disease
R34 T209 T208 agent by,caused
R35 T210 T211 det a,mutation
R36 T211 T209 pobj mutation,by
R37 T212 T213 punct ~,1
R38 T213 T214 nummod 1,kb
R39 T214 T211 compound kb,mutation
R40 T215 T211 compound CLN3,mutation
R41 T216 T195 punct .,is
R42 T218 T219 det The,loss
R44 T220 T219 amod resulting,loss
R45 T222 T219 prep of,loss
R46 T223 T224 compound battenin,activity
R47 T224 T222 pobj activity,of
R48 T225 T221 prep to,leads
R49 T226 T225 pobj deposition,to
R50 T227 T226 prep of,deposition
R51 T228 T229 amod mitochondrial,synthase
R53 T230 T229 compound ATP,synthase
R54 T231 T229 punct ", ",synthase
R55 T232 T233 compound subunit,c
R56 T233 T229 npadvmod c,synthase
R57 T234 T226 cc and,deposition
R58 T235 T236 det a,loss
R60 T237 T236 amod specific,loss
R61 T238 T236 prep of,loss
R62 T239 T240 compound CNS,neurons
R63 T240 T238 pobj neurons,of
R64 T241 T221 punct .,leads
R65 T243 T244 nsubj We,generated
R66 T245 T244 advmod previously,generated
R67 T246 T247 nmod Cln3Δex7,mice
R68 T247 T244 dobj mice,generated
R69 T248 T246 punct /,Cln3Δex7
R70 T249 T246 nummod 8,Cln3Δex7
R71 T250 T247 amod knock,mice
R72 T251 T250 punct -,knock
R73 T252 T250 prt in,knock
R74 T253 T247 punct ", ",mice
R75 T254 T255 dep which,replicate
R76 T255 T247 relcl replicate,mice
R77 T256 T257 det the,mutation
R78 T257 T255 dobj mutation,replicate
R79 T258 T257 amod common,mutation
R80 T259 T257 compound JNCL,mutation
R81 T260 T255 punct ", ",replicate
R82 T261 T255 conj express,replicate
R83 T262 T263 compound mutant,battenin
R87 T266 T267 npadvmod JNCL,like
R89 T268 T267 punct -,like
R90 T269 T265 dobj pathology,display
R91 T270 T244 punct .,generated
R31 T206 T208 advmod commonly,caused
R43 T219 T221 nsubj loss,leads
R52 T229 T227 pobj synthase,of
R59 T236 T226 conj loss,deposition
R88 T267 T269 amod like,pathology

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T110 44-53 UBERON_EXT:childhood denotes childhood
T111 116-117 CHEBI_SO_EXT:base denotes b
T112 118-122 PR_EXT:000005591 denotes CLN3
T113 123-131 SO_EXT:sequence_alteration_entity_or_process denotes mutation
T114 155-163 PR_EXT:000005591 denotes battenin
T115 196-209 GO:0005739 denotes mitochondrial
T116 196-233 PR_EXT:000022190 denotes mitochondrial ATP synthase, subunit c
T117 210-213 CHEBI_EXT:ATP denotes ATP
T118 257-260 UBERON:0001017 denotes CNS
T119 257-268 CL:0000117 denotes CNS neurons
T120 294-298 PR_EXT:000005591 denotes Cln3
T121 314-318 NCBITaxon:10088 denotes mice
T122 352-360 SO_EXT:sequence_alteration_entity_or_process denotes mutation
T123 362-369 GO:0010467 denotes express
T124 370-376 SO_EXT:sequence_altered_entity_or_alteration_process denotes mutant
T125 377-385 PR_EXT:000005591 denotes battenin