PMC:539061 / 8505-9260
Annnotations
craft-ca-core-dev
Below, discontinuous spans are shown in the chain model. You can change it to the bag model.
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T2404 | 9-14 | PR:000015308 | denotes | Snail |
| T2405 | 66-70 | GO:0001837 | denotes | EMTs |
| T2406 | 187-210 | GO:0005911 | denotes | intercellular junctions |
| T2407 | 263-268 | PR:000015308 | denotes | Snail |
| T2408 | 331-341 | UBERON:0000483 | denotes | epithelial |
| T2409 | 373-386 | UBERON:0002073 | denotes | hair follicle |
| T2410 | 453-458 | PR:000015308 | denotes | Snail |
| T2411 | 480-485 | PR:000009751 | denotes | LEF-1 |
| T2412 | 486-495 | PR:000002198 | denotes | β-catenin |
| T2413 | 515-525 | PR:000001447 | denotes | E-cadherin |
| T2414 | 526-536 | GO:0010467 | denotes | expression |
| T2415 | 540-553 | CL:0000312 | denotes | keratinocytes |
| T2416 | 604-609 | PR:000009751 | denotes | LEF-1 |
| T2417 | 610-619 | PR:000002198 | denotes | β-catenin |
| T2418 | 623-636 | UBERON:0002073 | denotes | hair follicle |
| T2419 | 623-650 | GO:0031069 | denotes | hair follicle morphogenesis |
| T2420 | 691-696 | PR:000015308 | denotes | Snail |
| T2421 | 697-701 | PR:000015309 | denotes | Slug |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 15630473-14644200-84810253 | 212-214 | 14644200 | denotes | 18 |
| 15630473-12646922-84810254 | 555-556 | 12646922 | denotes | 4 |
| 15630473-12646922-84810255 | 652-653 | 12646922 | denotes | 4 |
| 15630473-7958926-84810256 | 654-656 | 7958926 | denotes | 19 |
| T89400 | 212-214 | 14644200 | denotes | 18 |
| T54398 | 555-556 | 12646922 | denotes | 4 |
| T55026 | 652-653 | 12646922 | denotes | 4 |
| T82528 | 654-656 | 7958926 | denotes | 19 |
craft-ca-core-ex-dev
Below, discontinuous spans are shown in the chain model. You can change it to the bag model.
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T2533 | 9-14 | PR_EXT:000015308 | denotes | Snail |
| T2534 | 66-70 | GO:0001837 | denotes | EMTs |
| T2535 | 134-149 | GO_EXT:negative_regulation | denotes | down-regulation |
| T2536 | 187-210 | GO:0005911 | denotes | intercellular junctions |
| T2537 | 192-200 | CL_GO_EXT:cell | denotes | cellular |
| T2538 | 263-268 | PR_EXT:000015308 | denotes | Snail |
| T2539 | 331-341 | UBERON:0000483 | denotes | epithelial |
| T2540 | 373-386 | UBERON:0002073 | denotes | hair follicle |
| T2541 | 453-458 | PR_EXT:000015308 | denotes | Snail |
| T2542 | 480-485 | PR_EXT:000009751 | denotes | LEF-1 |
| T2543 | 486-495 | PR_EXT:000002198 | denotes | β-catenin |
| T2544 | 499-514 | GO_EXT:negative_regulation | denotes | down-regulating |
| T2545 | 515-525 | PR_EXT:000001447 | denotes | E-cadherin |
| T2546 | 526-536 | GO:0010467 | denotes | expression |
| T2547 | 540-553 | CL:0000312 | denotes | keratinocytes |
| T2548 | 604-609 | PR_EXT:000009751 | denotes | LEF-1 |
| T2549 | 610-619 | PR_EXT:000002198 | denotes | β-catenin |
| T2550 | 623-636 | UBERON:0002073 | denotes | hair follicle |
| T2551 | 623-650 | GO:0031069 | denotes | hair follicle morphogenesis |
| T2552 | 691-696 | PR_EXT:000015308 | denotes | Snail |
| T2553 | 697-701 | PR_EXT:000015309 | denotes | Slug |
craft-sa-dev
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T2718 | 0-8 | IN | denotes | Although |
| T2719 | 50-60 | VBN | denotes | associated |
| T2720 | 9-14 | NN | denotes | Snail |
| T2721 | 22-29 | NNS | denotes | members |
| T2722 | 15-21 | NN | denotes | family |
| T2723 | 30-33 | VBP | denotes | are |
| T2724 | 34-38 | RBS | denotes | most |
| T2725 | 39-49 | RB | denotes | frequently |
| T2726 | 82-93 | VBP | denotes | participate |
| T2727 | 61-65 | IN | denotes | with |
| T2728 | 66-70 | NNS | denotes | EMTs |
| T2729 | 70-72 | , | denotes | , |
| T2730 | 72-76 | PRP | denotes | they |
| T2731 | 77-81 | RB | denotes | also |
| T2732 | 94-96 | IN | denotes | in |
| T2733 | 97-101 | JJ | denotes | many |
| T2734 | 112-121 | NNS | denotes | processes |
| T2735 | 102-111 | JJ | denotes | malignant |
| T2736 | 122-131 | VBG | denotes | involving |
| T2737 | 132-133 | DT | denotes | a |
| T2738 | 139-149 | NN | denotes | regulation |
| T2739 | 134-138 | JJ | denotes | down |
| T2740 | 138-139 | HYPH | denotes | - |
| T2741 | 150-153 | CC | denotes | but |
| T2742 | 154-157 | RB | denotes | not |
| T2743 | 158-159 | DT | denotes | a |
| T2744 | 173-183 | NN | denotes | abrogation |
| T2745 | 160-172 | JJ | denotes | quantitative |
| T2746 | 184-186 | IN | denotes | of |
| T2747 | 187-200 | JJ | denotes | intercellular |
| T2748 | 201-210 | NNS | denotes | junctions |
| T2749 | 211-212 | -LRB- | denotes | [ |
| T2750 | 212-214 | CD | denotes | 18 |
| T2751 | 214-215 | -RRB- | denotes | ] |
| T2752 | 215-216 | . | denotes | . |
| T2753 | 216-401 | sentence | denotes | The range of developmental processes in which Snail family members have been implicated thus includes the type of epithelial remodeling that is observed in hair follicle bud formation. |
| T2754 | 217-220 | DT | denotes | The |
| T2755 | 221-226 | NN | denotes | range |
| T2756 | 310-318 | VBZ | denotes | includes |
| T2757 | 227-229 | IN | denotes | of |
| T2758 | 230-243 | JJ | denotes | developmental |
| T2759 | 244-253 | NNS | denotes | processes |
| T2760 | 254-256 | IN | denotes | in |
| T2761 | 294-304 | VBN | denotes | implicated |
| T2762 | 257-262 | WDT | denotes | which |
| T2763 | 263-268 | NN | denotes | Snail |
| T2764 | 276-283 | NNS | denotes | members |
| T2765 | 269-275 | NN | denotes | family |
| T2766 | 284-288 | VBP | denotes | have |
| T2767 | 289-293 | VBN | denotes | been |
| T2768 | 305-309 | RB | denotes | thus |
| T2769 | 319-322 | DT | denotes | the |
| T2770 | 323-327 | NN | denotes | type |
| T2771 | 328-330 | IN | denotes | of |
| T2772 | 331-341 | JJ | denotes | epithelial |
| T2773 | 342-352 | NN | denotes | remodeling |
| T2774 | 353-357 | WDT | denotes | that |
| T2775 | 361-369 | VBN | denotes | observed |
| T2776 | 358-360 | VBZ | denotes | is |
| T2777 | 370-372 | IN | denotes | in |
| T2778 | 373-377 | NN | denotes | hair |
| T2779 | 378-386 | NN | denotes | follicle |
| T2780 | 387-390 | NN | denotes | bud |
| T2781 | 391-400 | NN | denotes | formation |
| T2782 | 400-401 | . | denotes | . |
| T2783 | 401-755 | sentence | denotes | Given our prior observation that exogenously added Snail can participate with LEF-1/β-catenin in down-regulating E-cadherin expression in keratinocytes [4], coupled with the established requirement for LEF-1/β-catenin in hair follicle morphogenesis [4,19], we turned to addressing whether Snail/Slug family members might also participate in the process. |
| T2784 | 402-407 | VBN | denotes | Given |
| T2785 | 662-668 | VBD | denotes | turned |
| T2786 | 408-411 | PRP$ | denotes | our |
| T2787 | 418-429 | NN | denotes | observation |
| T2788 | 412-417 | JJ | denotes | prior |
| T2789 | 430-434 | IN | denotes | that |
| T2790 | 463-474 | VB | denotes | participate |
| T2791 | 435-446 | RB | denotes | exogenously |
| T2792 | 447-452 | VBN | denotes | added |
| T2793 | 453-458 | NN | denotes | Snail |
| T2794 | 459-462 | MD | denotes | can |
| T2795 | 475-479 | IN | denotes | with |
| T2796 | 480-483 | NN | denotes | LEF |
| T2797 | 483-484 | HYPH | denotes | - |
| T2798 | 484-485 | CD | denotes | 1 |
| T2799 | 485-486 | HYPH | denotes | / |
| T2800 | 486-487 | NN | denotes | β |
| T2801 | 488-495 | NN | denotes | catenin |
| T2802 | 487-488 | HYPH | denotes | - |
| T2803 | 496-498 | IN | denotes | in |
| T2804 | 499-503 | RB | denotes | down |
| T2805 | 504-514 | VBG | denotes | regulating |
| T2806 | 503-504 | HYPH | denotes | - |
| T2807 | 515-516 | NN | denotes | E |
| T2808 | 517-525 | NN | denotes | cadherin |
| T2809 | 516-517 | HYPH | denotes | - |
| T2810 | 526-536 | NN | denotes | expression |
| T2811 | 537-539 | IN | denotes | in |
| T2812 | 540-553 | NNS | denotes | keratinocytes |
| T2813 | 554-555 | -LRB- | denotes | [ |
| T2814 | 555-556 | CD | denotes | 4 |
| T2815 | 556-557 | -RRB- | denotes | ] |
| T2816 | 557-559 | , | denotes | , |
| T2817 | 559-566 | VBN | denotes | coupled |
| T2818 | 567-571 | IN | denotes | with |
| T2819 | 572-575 | DT | denotes | the |
| T2820 | 588-599 | NN | denotes | requirement |
| T2821 | 576-587 | JJ | denotes | established |
| T2822 | 600-603 | IN | denotes | for |
| T2823 | 604-607 | NN | denotes | LEF |
| T2824 | 607-608 | HYPH | denotes | - |
| T2825 | 608-609 | CD | denotes | 1 |
| T2826 | 609-610 | HYPH | denotes | / |
| T2827 | 610-611 | NN | denotes | β |
| T2828 | 612-619 | NN | denotes | catenin |
| T2829 | 611-612 | HYPH | denotes | - |
| T2830 | 620-622 | IN | denotes | in |
| T2831 | 623-627 | NN | denotes | hair |
| T2832 | 628-636 | NN | denotes | follicle |
| T2833 | 637-650 | NN | denotes | morphogenesis |
| T2834 | 651-652 | -LRB- | denotes | [ |
| T2835 | 654-656 | CD | denotes | 19 |
| T2836 | 652-653 | CD | denotes | 4 |
| T2837 | 653-654 | , | denotes | , |
| T2838 | 656-657 | -RRB- | denotes | ] |
| T2839 | 657-659 | , | denotes | , |
| T2840 | 659-661 | PRP | denotes | we |
| T2841 | 669-671 | IN | denotes | to |
| T2842 | 672-682 | VBG | denotes | addressing |
| T2843 | 683-690 | IN | denotes | whether |
| T2844 | 728-739 | VB | denotes | participate |
| T2845 | 691-696 | NN | denotes | Snail |
| T2846 | 697-701 | NN | denotes | Slug |
| T2847 | 696-697 | HYPH | denotes | / |
| T2848 | 709-716 | NNS | denotes | members |
| T2849 | 702-708 | NN | denotes | family |
| T2850 | 717-722 | MD | denotes | might |
| T2851 | 723-727 | RB | denotes | also |
| T2852 | 740-742 | IN | denotes | in |
| T2853 | 743-746 | DT | denotes | the |
| T2854 | 747-754 | NN | denotes | process |
| T2855 | 754-755 | . | denotes | . |
| R1447 | T2718 | T2719 | mark | Although,associated |
| R1448 | T2719 | T2726 | advcl | associated,participate |
| R1449 | T2720 | T2721 | compound | Snail,members |
| R1450 | T2721 | T2719 | nsubjpass | members,associated |
| R1451 | T2722 | T2721 | compound | family,members |
| R1452 | T2723 | T2719 | auxpass | are,associated |
| R1453 | T2724 | T2725 | advmod | most,frequently |
| R1454 | T2725 | T2719 | advmod | frequently,associated |
| R1455 | T2727 | T2719 | prep | with,associated |
| R1456 | T2728 | T2727 | pobj | EMTs,with |
| R1457 | T2729 | T2726 | punct | ", ",participate |
| R1458 | T2730 | T2726 | nsubj | they,participate |
| R1459 | T2731 | T2726 | advmod | also,participate |
| R1460 | T2732 | T2726 | prep | in,participate |
| R1461 | T2733 | T2734 | amod | many,processes |
| R1462 | T2734 | T2732 | pobj | processes,in |
| R1463 | T2735 | T2734 | amod | malignant,processes |
| R1464 | T2736 | T2734 | acl | involving,processes |
| R1465 | T2737 | T2738 | det | a,regulation |
| R1466 | T2738 | T2736 | dobj | regulation,involving |
| R1467 | T2739 | T2738 | amod | down,regulation |
| R1468 | T2740 | T2738 | punct | -,regulation |
| R1469 | T2741 | T2738 | cc | but,regulation |
| R1470 | T2742 | T2741 | neg | not,but |
| R1471 | T2743 | T2744 | det | a,abrogation |
| R1472 | T2744 | T2738 | conj | abrogation,regulation |
| R1473 | T2745 | T2744 | amod | quantitative,abrogation |
| R1474 | T2746 | T2738 | prep | of,regulation |
| R1475 | T2747 | T2748 | amod | intercellular,junctions |
| R1476 | T2748 | T2746 | pobj | junctions,of |
| R1477 | T2749 | T2750 | punct | [,18 |
| R1478 | T2750 | T2726 | parataxis | 18,participate |
| R1479 | T2751 | T2750 | punct | ],18 |
| R1480 | T2752 | T2726 | punct | .,participate |
| R1481 | T2754 | T2755 | det | The,range |
| R1482 | T2755 | T2756 | nsubj | range,includes |
| R1483 | T2757 | T2755 | prep | of,range |
| R1484 | T2758 | T2759 | amod | developmental,processes |
| R1485 | T2759 | T2757 | pobj | processes,of |
| R1486 | T2760 | T2761 | prep | in,implicated |
| R1487 | T2761 | T2759 | relcl | implicated,processes |
| R1488 | T2762 | T2760 | pobj | which,in |
| R1489 | T2763 | T2764 | compound | Snail,members |
| R1490 | T2764 | T2761 | nsubjpass | members,implicated |
| R1491 | T2765 | T2764 | compound | family,members |
| R1492 | T2766 | T2761 | aux | have,implicated |
| R1493 | T2767 | T2761 | auxpass | been,implicated |
| R1494 | T2768 | T2756 | advmod | thus,includes |
| R1495 | T2769 | T2770 | det | the,type |
| R1496 | T2770 | T2756 | dobj | type,includes |
| R1497 | T2771 | T2770 | prep | of,type |
| R1498 | T2772 | T2773 | amod | epithelial,remodeling |
| R1499 | T2773 | T2771 | pobj | remodeling,of |
| R1500 | T2774 | T2775 | dep | that,observed |
| R1501 | T2775 | T2770 | relcl | observed,type |
| R1502 | T2776 | T2775 | auxpass | is,observed |
| R1503 | T2777 | T2775 | prep | in,observed |
| R1504 | T2778 | T2779 | compound | hair,follicle |
| R1505 | T2779 | T2780 | compound | follicle,bud |
| R1506 | T2780 | T2781 | compound | bud,formation |
| R1507 | T2781 | T2777 | pobj | formation,in |
| R1508 | T2782 | T2756 | punct | .,includes |
| R1509 | T2784 | T2785 | prep | Given,turned |
| R1510 | T2786 | T2787 | poss | our,observation |
| R1511 | T2787 | T2784 | pobj | observation,Given |
| R1512 | T2788 | T2787 | amod | prior,observation |
| R1513 | T2789 | T2790 | mark | that,participate |
| R1514 | T2790 | T2787 | acl | participate,observation |
| R1515 | T2791 | T2792 | advmod | exogenously,added |
| R1516 | T2792 | T2793 | amod | added,Snail |
| R1517 | T2793 | T2790 | nsubj | Snail,participate |
| R1518 | T2794 | T2790 | aux | can,participate |
| R1519 | T2795 | T2790 | prep | with,participate |
| R1520 | T2796 | T2795 | pobj | LEF,with |
| R1521 | T2797 | T2796 | punct | -,LEF |
| R1522 | T2798 | T2796 | nummod | 1,LEF |
| R1523 | T2799 | T2796 | punct | /,LEF |
| R1524 | T2800 | T2801 | compound | β,catenin |
| R1525 | T2801 | T2796 | appos | catenin,LEF |
| R1526 | T2802 | T2801 | punct | -,catenin |
| R1527 | T2803 | T2790 | prep | in,participate |
| R1528 | T2804 | T2805 | advmod | down,regulating |
| R1529 | T2805 | T2803 | pcomp | regulating,in |
| R1530 | T2806 | T2805 | punct | -,regulating |
| R1531 | T2807 | T2808 | compound | E,cadherin |
| R1532 | T2808 | T2810 | compound | cadherin,expression |
| R1533 | T2809 | T2808 | punct | -,cadherin |
| R1534 | T2810 | T2805 | dobj | expression,regulating |
| R1535 | T2811 | T2790 | prep | in,participate |
| R1536 | T2812 | T2811 | pobj | keratinocytes,in |
| R1537 | T2813 | T2814 | punct | [,4 |
| R1538 | T2814 | T2790 | parataxis | 4,participate |
| R1539 | T2815 | T2814 | punct | ],4 |
| R1540 | T2816 | T2787 | punct | ", ",observation |
| R1541 | T2817 | T2787 | acl | coupled,observation |
| R1542 | T2818 | T2817 | prep | with,coupled |
| R1543 | T2819 | T2820 | det | the,requirement |
| R1544 | T2820 | T2818 | pobj | requirement,with |
| R1545 | T2821 | T2820 | amod | established,requirement |
| R1546 | T2822 | T2820 | prep | for,requirement |
| R1547 | T2823 | T2822 | pobj | LEF,for |
| R1548 | T2824 | T2823 | punct | -,LEF |
| R1549 | T2825 | T2823 | nummod | 1,LEF |
| R1550 | T2826 | T2823 | punct | /,LEF |
| R1551 | T2827 | T2828 | compound | β,catenin |
| R1552 | T2828 | T2823 | appos | catenin,LEF |
| R1553 | T2829 | T2828 | punct | -,catenin |
| R1554 | T2830 | T2820 | prep | in,requirement |
| R1555 | T2831 | T2832 | compound | hair,follicle |
| R1556 | T2832 | T2833 | compound | follicle,morphogenesis |
| R1557 | T2833 | T2830 | pobj | morphogenesis,in |
| R1558 | T2834 | T2835 | punct | [,19 |
| R1559 | T2835 | T2817 | parataxis | 19,coupled |
| R1560 | T2836 | T2835 | nummod | 4,19 |
| R1561 | T2837 | T2835 | punct | ",",19 |
| R1562 | T2838 | T2835 | punct | ],19 |
| R1563 | T2839 | T2785 | punct | ", ",turned |
| R1564 | T2840 | T2785 | nsubj | we,turned |
| R1565 | T2841 | T2785 | prep | to,turned |
| R1566 | T2842 | T2841 | pcomp | addressing,to |
| R1567 | T2843 | T2844 | mark | whether,participate |
| R1568 | T2844 | T2842 | ccomp | participate,addressing |
| R1569 | T2845 | T2846 | compound | Snail,Slug |
| R1570 | T2846 | T2848 | compound | Slug,members |
| R1571 | T2847 | T2846 | punct | /,Slug |
| R1572 | T2848 | T2844 | nsubj | members,participate |
| R1573 | T2849 | T2848 | compound | family,members |
| R1574 | T2850 | T2844 | aux | might,participate |
| R1575 | T2851 | T2844 | advmod | also,participate |
| R1576 | T2852 | T2844 | prep | in,participate |
| R1577 | T2853 | T2854 | det | the,process |
| R1578 | T2854 | T2852 | pobj | process,in |
| R1579 | T2855 | T2785 | punct | .,turned |