Id |
Subject |
Object |
Predicate |
Lexical cue |
T2028 |
0-2 |
IN |
denotes |
In |
T2029 |
25-35 |
VBD |
denotes |
discovered |
T2030 |
3-6 |
DT |
denotes |
the |
T2031 |
15-20 |
NN |
denotes |
study |
T2032 |
7-14 |
JJ |
denotes |
present |
T2033 |
20-22 |
, |
denotes |
, |
T2034 |
22-24 |
PRP |
denotes |
we |
T2035 |
36-40 |
IN |
denotes |
that |
T2036 |
50-59 |
VBN |
denotes |
expressed |
T2037 |
41-46 |
NN |
denotes |
Snail |
T2038 |
47-49 |
VBZ |
denotes |
is |
T2039 |
60-67 |
RB |
denotes |
briefly |
T2040 |
68-70 |
IN |
denotes |
at |
T2041 |
71-73 |
DT |
denotes |
an |
T2042 |
80-85 |
NN |
denotes |
stage |
T2043 |
74-79 |
JJ |
denotes |
early |
T2044 |
86-88 |
IN |
denotes |
of |
T2045 |
89-93 |
NN |
denotes |
hair |
T2046 |
94-97 |
NN |
denotes |
bud |
T2047 |
98-107 |
NN |
denotes |
formation |
T2048 |
107-109 |
, |
denotes |
, |
T2049 |
109-113 |
WRB |
denotes |
when |
T2050 |
173-177 |
VBP |
denotes |
take |
T2051 |
114-115 |
NN |
denotes |
E |
T2052 |
116-124 |
NN |
denotes |
cadherin |
T2053 |
115-116 |
HYPH |
denotes |
- |
T2054 |
125-129 |
JJ |
denotes |
down |
T2055 |
130-140 |
NN |
denotes |
regulation |
T2056 |
129-130 |
HYPH |
denotes |
- |
T2057 |
141-144 |
CC |
denotes |
and |
T2058 |
145-155 |
NN |
denotes |
activation |
T2059 |
156-158 |
IN |
denotes |
of |
T2060 |
159-172 |
NN |
denotes |
proliferation |
T2061 |
178-183 |
NN |
denotes |
place |
T2062 |
183-184 |
. |
denotes |
. |
T2063 |
184-287 |
sentence |
denotes |
Thereafter, Snail disappears and remains absent during subsequent follicle down-growth and maturation. |
T2064 |
185-195 |
RB |
denotes |
Thereafter |
T2065 |
203-213 |
VBZ |
denotes |
disappears |
T2066 |
195-197 |
, |
denotes |
, |
T2067 |
197-202 |
NN |
denotes |
Snail |
T2068 |
214-217 |
CC |
denotes |
and |
T2069 |
218-225 |
VBZ |
denotes |
remains |
T2070 |
226-232 |
JJ |
denotes |
absent |
T2071 |
233-239 |
IN |
denotes |
during |
T2072 |
240-250 |
JJ |
denotes |
subsequent |
T2073 |
265-271 |
NN |
denotes |
growth |
T2074 |
251-259 |
NN |
denotes |
follicle |
T2075 |
260-264 |
JJ |
denotes |
down |
T2076 |
264-265 |
HYPH |
denotes |
- |
T2077 |
272-275 |
CC |
denotes |
and |
T2078 |
276-286 |
NN |
denotes |
maturation |
T2079 |
286-287 |
. |
denotes |
. |
T2080 |
287-547 |
sentence |
denotes |
This exquisite pattern appears to be functionally relevant since altering it in vivo correspondingly affects features associated with hair bud formation, including down-regulation of E-cadherin, increased proliferation, and repressed terminal differentiation. |
T2081 |
288-292 |
DT |
denotes |
This |
T2082 |
303-310 |
NN |
denotes |
pattern |
T2083 |
293-302 |
JJ |
denotes |
exquisite |
T2084 |
311-318 |
VBZ |
denotes |
appears |
T2085 |
319-321 |
TO |
denotes |
to |
T2086 |
322-324 |
VB |
denotes |
be |
T2087 |
325-337 |
RB |
denotes |
functionally |
T2088 |
338-346 |
JJ |
denotes |
relevant |
T2089 |
347-352 |
IN |
denotes |
since |
T2090 |
389-396 |
VBZ |
denotes |
affects |
T2091 |
353-361 |
VBG |
denotes |
altering |
T2092 |
362-364 |
PRP |
denotes |
it |
T2093 |
365-367 |
FW |
denotes |
in |
T2094 |
368-372 |
FW |
denotes |
vivo |
T2095 |
373-388 |
RB |
denotes |
correspondingly |
T2096 |
397-405 |
NNS |
denotes |
features |
T2097 |
406-416 |
VBN |
denotes |
associated |
T2098 |
417-421 |
IN |
denotes |
with |
T2099 |
422-426 |
NN |
denotes |
hair |
T2100 |
427-430 |
NN |
denotes |
bud |
T2101 |
431-440 |
NN |
denotes |
formation |
T2102 |
440-442 |
, |
denotes |
, |
T2103 |
442-451 |
VBG |
denotes |
including |
T2104 |
452-456 |
NN |
denotes |
down |
T2105 |
457-467 |
NN |
denotes |
regulation |
T2106 |
456-457 |
HYPH |
denotes |
- |
T2107 |
468-470 |
IN |
denotes |
of |
T2108 |
471-472 |
NN |
denotes |
E |
T2109 |
473-481 |
NN |
denotes |
cadherin |
T2110 |
472-473 |
HYPH |
denotes |
- |
T2111 |
481-483 |
, |
denotes |
, |
T2112 |
483-492 |
VBN |
denotes |
increased |
T2113 |
493-506 |
NN |
denotes |
proliferation |
T2114 |
506-508 |
, |
denotes |
, |
T2115 |
508-511 |
CC |
denotes |
and |
T2116 |
512-521 |
VBN |
denotes |
repressed |
T2117 |
531-546 |
NN |
denotes |
differentiation |
T2118 |
522-530 |
JJ |
denotes |
terminal |
T2119 |
546-547 |
. |
denotes |
. |
T2120 |
547-793 |
sentence |
denotes |
Although the temporal spike of Snail in the hair bud is reflected at the mRNA level and seems to follow Wnt signaling and BMP inhibition, LEF-1/β-catenin activation does not appear to induce Snail gene expression in embryonic skin keratinocytes. |
T2121 |
548-556 |
IN |
denotes |
Although |
T2122 |
604-613 |
VBN |
denotes |
reflected |
T2123 |
557-560 |
DT |
denotes |
the |
T2124 |
570-575 |
NN |
denotes |
spike |
T2125 |
561-569 |
JJ |
denotes |
temporal |
T2126 |
576-578 |
IN |
denotes |
of |
T2127 |
579-584 |
NN |
denotes |
Snail |
T2128 |
585-587 |
IN |
denotes |
in |
T2129 |
588-591 |
DT |
denotes |
the |
T2130 |
597-600 |
NN |
denotes |
bud |
T2131 |
592-596 |
NN |
denotes |
hair |
T2132 |
601-603 |
VBZ |
denotes |
is |
T2133 |
722-728 |
VB |
denotes |
appear |
T2134 |
614-616 |
IN |
denotes |
at |
T2135 |
617-620 |
DT |
denotes |
the |
T2136 |
626-631 |
NN |
denotes |
level |
T2137 |
621-625 |
NN |
denotes |
mRNA |
T2138 |
632-635 |
CC |
denotes |
and |
T2139 |
636-641 |
VBZ |
denotes |
seems |
T2140 |
642-644 |
TO |
denotes |
to |
T2141 |
645-651 |
VB |
denotes |
follow |
T2142 |
652-655 |
NN |
denotes |
Wnt |
T2143 |
656-665 |
NN |
denotes |
signaling |
T2144 |
666-669 |
CC |
denotes |
and |
T2145 |
670-673 |
NN |
denotes |
BMP |
T2146 |
674-684 |
NN |
denotes |
inhibition |
T2147 |
684-686 |
, |
denotes |
, |
T2148 |
686-689 |
NN |
denotes |
LEF |
T2149 |
702-712 |
NN |
denotes |
activation |
T2150 |
689-690 |
HYPH |
denotes |
- |
T2151 |
690-691 |
CD |
denotes |
1 |
T2152 |
691-692 |
HYPH |
denotes |
/ |
T2153 |
692-693 |
NN |
denotes |
β |
T2154 |
694-701 |
NN |
denotes |
catenin |
T2155 |
693-694 |
HYPH |
denotes |
- |
T2156 |
713-717 |
VBZ |
denotes |
does |
T2157 |
718-721 |
RB |
denotes |
not |
T2158 |
729-731 |
TO |
denotes |
to |
T2159 |
732-738 |
VB |
denotes |
induce |
T2160 |
739-744 |
NN |
denotes |
Snail |
T2161 |
750-760 |
NN |
denotes |
expression |
T2162 |
745-749 |
NN |
denotes |
gene |
T2163 |
761-763 |
IN |
denotes |
in |
T2164 |
764-773 |
JJ |
denotes |
embryonic |
T2165 |
779-792 |
NNS |
denotes |
keratinocytes |
T2166 |
774-778 |
NN |
denotes |
skin |
T2167 |
792-793 |
. |
denotes |
. |
T2168 |
793-1052 |
sentence |
denotes |
In contrast, we provide in vitro, transgenic (Tg), and gene targeting evidence to show that TGF-β2 and small phenotype– and mothers against decapentaplegic–related protein 2 (SMAD2) signaling are upstream inducers of Snail gene expression in skin epithelium. |
T2169 |
794-796 |
IN |
denotes |
In |
T2170 |
810-817 |
VBP |
denotes |
provide |
T2171 |
797-805 |
NN |
denotes |
contrast |
T2172 |
805-807 |
, |
denotes |
, |
T2173 |
807-809 |
PRP |
denotes |
we |
T2174 |
818-820 |
FW |
denotes |
in |
T2175 |
821-826 |
FW |
denotes |
vitro |
T2176 |
864-872 |
NN |
denotes |
evidence |
T2177 |
826-828 |
, |
denotes |
, |
T2178 |
828-838 |
JJ |
denotes |
transgenic |
T2179 |
839-840 |
-LRB- |
denotes |
( |
T2180 |
840-842 |
JJ |
denotes |
Tg |
T2181 |
842-843 |
-RRB- |
denotes |
) |
T2182 |
843-845 |
, |
denotes |
, |
T2183 |
845-848 |
CC |
denotes |
and |
T2184 |
849-853 |
NN |
denotes |
gene |
T2185 |
854-863 |
VBG |
denotes |
targeting |
T2186 |
873-875 |
TO |
denotes |
to |
T2187 |
876-880 |
VB |
denotes |
show |
T2188 |
881-885 |
IN |
denotes |
that |
T2189 |
986-989 |
VBP |
denotes |
are |
T2190 |
886-889 |
NN |
denotes |
TGF |
T2191 |
890-892 |
NN |
denotes |
β2 |
T2192 |
889-890 |
HYPH |
denotes |
- |
T2193 |
976-985 |
NN |
denotes |
signaling |
T2194 |
893-896 |
CC |
denotes |
and |
T2195 |
897-902 |
JJ |
denotes |
small |
T2196 |
903-912 |
NN |
denotes |
phenotype |
T2197 |
950-957 |
VBN |
denotes |
related |
T2198 |
912-913 |
-LRB- |
denotes |
– |
T2199 |
914-917 |
CC |
denotes |
and |
T2200 |
918-925 |
NNS |
denotes |
mothers |
T2201 |
926-933 |
IN |
denotes |
against |
T2202 |
934-949 |
NN |
denotes |
decapentaplegic |
T2203 |
949-950 |
-RRB- |
denotes |
– |
T2204 |
958-965 |
NN |
denotes |
protein |
T2205 |
966-967 |
CD |
denotes |
2 |
T2206 |
968-969 |
-LRB- |
denotes |
( |
T2207 |
969-974 |
NN |
denotes |
SMAD2 |
T2208 |
974-975 |
-RRB- |
denotes |
) |
T2209 |
990-998 |
JJ |
denotes |
upstream |
T2210 |
999-1007 |
NNS |
denotes |
inducers |
T2211 |
1008-1010 |
IN |
denotes |
of |
T2212 |
1011-1016 |
NN |
denotes |
Snail |
T2213 |
1022-1032 |
NN |
denotes |
expression |
T2214 |
1017-1021 |
NN |
denotes |
gene |
T2215 |
1033-1035 |
IN |
denotes |
in |
T2216 |
1036-1040 |
NN |
denotes |
skin |
T2217 |
1041-1051 |
NN |
denotes |
epithelium |
T2218 |
1051-1052 |
. |
denotes |
. |
T2219 |
1052-1183 |
sentence |
denotes |
In the absence of TGF-β2 signaling and Snail gene expression, hair placodes can form, but further follicle down-growth is blocked. |
T2220 |
1053-1055 |
IN |
denotes |
In |
T2221 |
1133-1137 |
VB |
denotes |
form |
T2222 |
1056-1059 |
DT |
denotes |
the |
T2223 |
1060-1067 |
NN |
denotes |
absence |
T2224 |
1068-1070 |
IN |
denotes |
of |
T2225 |
1071-1074 |
NN |
denotes |
TGF |
T2226 |
1075-1077 |
NN |
denotes |
β2 |
T2227 |
1074-1075 |
HYPH |
denotes |
- |
T2228 |
1078-1087 |
NN |
denotes |
signaling |
T2229 |
1088-1091 |
CC |
denotes |
and |
T2230 |
1092-1097 |
NN |
denotes |
Snail |
T2231 |
1103-1113 |
NN |
denotes |
expression |
T2232 |
1098-1102 |
NN |
denotes |
gene |
T2233 |
1113-1115 |
, |
denotes |
, |
T2234 |
1115-1119 |
NN |
denotes |
hair |
T2235 |
1120-1128 |
NNS |
denotes |
placodes |
T2236 |
1129-1132 |
MD |
denotes |
can |
T2237 |
1137-1139 |
, |
denotes |
, |
T2238 |
1139-1142 |
CC |
denotes |
but |
T2239 |
1143-1150 |
JJ |
denotes |
further |
T2240 |
1165-1171 |
NN |
denotes |
growth |
T2241 |
1151-1159 |
NN |
denotes |
follicle |
T2242 |
1160-1164 |
JJ |
denotes |
down |
T2243 |
1164-1165 |
HYPH |
denotes |
- |
T2244 |
1175-1182 |
VBN |
denotes |
blocked |
T2245 |
1172-1174 |
VBZ |
denotes |
is |
T2246 |
1182-1183 |
. |
denotes |
. |
T2247 |
1183-1361 |
sentence |
denotes |
Our studies point to the view that Snail likely functions downstream of cell fate specification, at a stage where the bud begins to exhibit enhanced proliferation and migration. |
T2248 |
1184-1187 |
PRP$ |
denotes |
Our |
T2249 |
1188-1195 |
NNS |
denotes |
studies |
T2250 |
1196-1201 |
VBP |
denotes |
point |
T2251 |
1202-1204 |
IN |
denotes |
to |
T2252 |
1205-1208 |
DT |
denotes |
the |
T2253 |
1209-1213 |
NN |
denotes |
view |
T2254 |
1214-1218 |
IN |
denotes |
that |
T2255 |
1232-1241 |
VBZ |
denotes |
functions |
T2256 |
1219-1224 |
NN |
denotes |
Snail |
T2257 |
1225-1231 |
RB |
denotes |
likely |
T2258 |
1242-1252 |
RB |
denotes |
downstream |
T2259 |
1253-1255 |
IN |
denotes |
of |
T2260 |
1256-1260 |
NN |
denotes |
cell |
T2261 |
1261-1265 |
NN |
denotes |
fate |
T2262 |
1266-1279 |
NN |
denotes |
specification |
T2263 |
1279-1281 |
, |
denotes |
, |
T2264 |
1281-1283 |
IN |
denotes |
at |
T2265 |
1284-1285 |
DT |
denotes |
a |
T2266 |
1286-1291 |
NN |
denotes |
stage |
T2267 |
1292-1297 |
WRB |
denotes |
where |
T2268 |
1306-1312 |
VBZ |
denotes |
begins |
T2269 |
1298-1301 |
DT |
denotes |
the |
T2270 |
1302-1305 |
NN |
denotes |
bud |
T2271 |
1313-1315 |
TO |
denotes |
to |
T2272 |
1316-1323 |
VB |
denotes |
exhibit |
T2273 |
1324-1332 |
VBN |
denotes |
enhanced |
T2274 |
1333-1346 |
NN |
denotes |
proliferation |
T2275 |
1347-1350 |
CC |
denotes |
and |
T2276 |
1351-1360 |
NN |
denotes |
migration |
T2277 |
1360-1361 |
. |
denotes |
. |
R1177 |
T2097 |
T2096 |
acl |
associated,features |
R1178 |
T2098 |
T2097 |
prep |
with,associated |
R1180 |
T2099 |
T2100 |
compound |
hair,bud |
R1181 |
T2100 |
T2101 |
compound |
bud,formation |
R1183 |
T2101 |
T2098 |
pobj |
formation,with |
R1184 |
T2102 |
T2096 |
punct |
", ",features |
R1185 |
T2103 |
T2096 |
prep |
including,features |
R1187 |
T2104 |
T2105 |
compound |
down,regulation |
R1188 |
T2105 |
T2103 |
pobj |
regulation,including |
R1189 |
T2028 |
T2029 |
prep |
In,discovered |
R1190 |
T2106 |
T2105 |
punct |
-,regulation |
R1191 |
T2107 |
T2105 |
prep |
of,regulation |
R1192 |
T2108 |
T2109 |
compound |
E,cadherin |
R1193 |
T2109 |
T2107 |
pobj |
cadherin,of |
R1194 |
T2030 |
T2031 |
det |
the,study |
R1195 |
T2110 |
T2109 |
punct |
-,cadherin |
R1196 |
T2111 |
T2105 |
punct |
", ",regulation |
R1197 |
T2112 |
T2113 |
amod |
increased,proliferation |
R1198 |
T2113 |
T2105 |
conj |
proliferation,regulation |
R1199 |
T2031 |
T2028 |
pobj |
study,In |
R1200 |
T2114 |
T2113 |
punct |
", ",proliferation |
R1201 |
T2115 |
T2113 |
cc |
and,proliferation |
R1202 |
T2032 |
T2031 |
amod |
present,study |
R1203 |
T2116 |
T2117 |
amod |
repressed,differentiation |
R1204 |
T2117 |
T2113 |
conj |
differentiation,proliferation |
R1205 |
T2118 |
T2117 |
amod |
terminal,differentiation |
R1206 |
T2119 |
T2084 |
punct |
.,appears |
R1207 |
T2033 |
T2029 |
punct |
", ",discovered |
R1208 |
T2121 |
T2122 |
mark |
Although,reflected |
R1209 |
T2034 |
T2029 |
nsubj |
we,discovered |
R1210 |
T2122 |
T2133 |
advcl |
reflected,appear |
R1211 |
T2123 |
T2124 |
det |
the,spike |
R1212 |
T2035 |
T2036 |
mark |
that,expressed |
R1213 |
T2124 |
T2122 |
nsubjpass |
spike,reflected |
R1214 |
T2125 |
T2124 |
amod |
temporal,spike |
R1215 |
T2036 |
T2029 |
ccomp |
expressed,discovered |
R1216 |
T2126 |
T2124 |
prep |
of,spike |
R1217 |
T2127 |
T2126 |
pobj |
Snail,of |
R1218 |
T2037 |
T2036 |
nsubjpass |
Snail,expressed |
R1219 |
T2128 |
T2124 |
prep |
in,spike |
R1220 |
T2129 |
T2130 |
det |
the,bud |
R1221 |
T2130 |
T2128 |
pobj |
bud,in |
R1222 |
T2038 |
T2036 |
auxpass |
is,expressed |
R1223 |
T2131 |
T2130 |
compound |
hair,bud |
R1224 |
T2132 |
T2122 |
auxpass |
is,reflected |
R1225 |
T2039 |
T2036 |
advmod |
briefly,expressed |
R1226 |
T2134 |
T2122 |
prep |
at,reflected |
R1227 |
T2135 |
T2136 |
det |
the,level |
R1228 |
T2136 |
T2134 |
pobj |
level,at |
R1229 |
T2040 |
T2036 |
prep |
at,expressed |
R1230 |
T2137 |
T2136 |
compound |
mRNA,level |
R1231 |
T2138 |
T2122 |
cc |
and,reflected |
R1232 |
T2139 |
T2122 |
conj |
seems,reflected |
R1233 |
T2041 |
T2042 |
det |
an,stage |
R1234 |
T2140 |
T2141 |
aux |
to,follow |
R1235 |
T2141 |
T2139 |
xcomp |
follow,seems |
R1236 |
T2142 |
T2143 |
compound |
Wnt,signaling |
R1237 |
T2042 |
T2040 |
pobj |
stage,at |
R1238 |
T2143 |
T2141 |
dobj |
signaling,follow |
R1239 |
T2144 |
T2143 |
cc |
and,signaling |
R1240 |
T2043 |
T2042 |
amod |
early,stage |
R1241 |
T2145 |
T2146 |
compound |
BMP,inhibition |
R1242 |
T2146 |
T2143 |
conj |
inhibition,signaling |
R1243 |
T2147 |
T2133 |
punct |
", ",appear |
R1244 |
T2044 |
T2042 |
prep |
of,stage |
R1245 |
T2148 |
T2149 |
nmod |
LEF,activation |
R1246 |
T2149 |
T2133 |
nsubj |
activation,appear |
R1247 |
T2045 |
T2046 |
compound |
hair,bud |
R1248 |
T2150 |
T2148 |
punct |
-,LEF |
R1249 |
T2151 |
T2148 |
nummod |
1,LEF |
R1250 |
T2152 |
T2148 |
punct |
/,LEF |
R1251 |
T2046 |
T2047 |
compound |
bud,formation |
R1252 |
T2153 |
T2154 |
compound |
β,catenin |
R1253 |
T2154 |
T2148 |
appos |
catenin,LEF |
R1254 |
T2155 |
T2154 |
punct |
-,catenin |
R1255 |
T2047 |
T2044 |
pobj |
formation,of |
R1256 |
T2156 |
T2133 |
aux |
does,appear |
R1257 |
T2157 |
T2133 |
neg |
not,appear |
R1258 |
T2158 |
T2159 |
aux |
to,induce |
R1259 |
T2159 |
T2133 |
xcomp |
induce,appear |
R1260 |
T2160 |
T2161 |
compound |
Snail,expression |
R1261 |
T2161 |
T2159 |
dobj |
expression,induce |
R1262 |
T2162 |
T2161 |
compound |
gene,expression |
R1263 |
T2048 |
T2042 |
punct |
", ",stage |
R1264 |
T2163 |
T2159 |
prep |
in,induce |
R1265 |
T2164 |
T2165 |
amod |
embryonic,keratinocytes |
R1266 |
T2165 |
T2163 |
pobj |
keratinocytes,in |
R1267 |
T2166 |
T2165 |
compound |
skin,keratinocytes |
R1268 |
T2049 |
T2050 |
advmod |
when,take |
R1269 |
T2167 |
T2133 |
punct |
.,appear |
R1270 |
T2050 |
T2042 |
relcl |
take,stage |
R1271 |
T2169 |
T2170 |
prep |
In,provide |
R1272 |
T2171 |
T2169 |
pobj |
contrast,In |
R1273 |
T2051 |
T2052 |
compound |
E,cadherin |
R1274 |
T2172 |
T2170 |
punct |
", ",provide |
R1275 |
T2173 |
T2170 |
nsubj |
we,provide |
R1276 |
T2174 |
T2175 |
advmod |
in,vitro |
R1277 |
T2052 |
T2050 |
nsubj |
cadherin,take |
R1278 |
T2175 |
T2176 |
amod |
vitro,evidence |
R1279 |
T2176 |
T2170 |
dobj |
evidence,provide |
R1280 |
T2053 |
T2052 |
punct |
-,cadherin |
R1281 |
T2177 |
T2175 |
punct |
", ",vitro |
R1282 |
T2178 |
T2175 |
conj |
transgenic,vitro |
R1283 |
T2179 |
T2180 |
punct |
(,Tg |
R1284 |
T2054 |
T2055 |
amod |
down,regulation |
R1285 |
T2180 |
T2178 |
parataxis |
Tg,transgenic |
R1286 |
T2181 |
T2180 |
punct |
),Tg |
R1287 |
T2182 |
T2178 |
punct |
", ",transgenic |
R1288 |
T2055 |
T2052 |
appos |
regulation,cadherin |
R1289 |
T2183 |
T2178 |
cc |
and,transgenic |
R1290 |
T2184 |
T2185 |
npadvmod |
gene,targeting |
R1291 |
T2056 |
T2055 |
punct |
-,regulation |
R1292 |
T2185 |
T2178 |
conj |
targeting,transgenic |
R1293 |
T2186 |
T2187 |
aux |
to,show |
R1294 |
T2057 |
T2055 |
cc |
and,regulation |
R1295 |
T2187 |
T2170 |
advcl |
show,provide |
R1296 |
T2188 |
T2189 |
mark |
that,are |
R1297 |
T2058 |
T2055 |
conj |
activation,regulation |
R1298 |
T2059 |
T2058 |
prep |
of,activation |
R1299 |
T2189 |
T2187 |
ccomp |
are,show |
R1300 |
T2190 |
T2191 |
nmod |
TGF,β2 |
R1301 |
T2060 |
T2059 |
pobj |
proliferation,of |
R1302 |
T2191 |
T2193 |
nmod |
β2,signaling |
R1303 |
T2192 |
T2191 |
punct |
-,β2 |
R1304 |
T2193 |
T2189 |
nsubj |
signaling,are |
R1305 |
T2061 |
T2050 |
dobj |
place,take |
R1306 |
T2194 |
T2191 |
cc |
and,β2 |
R1307 |
T2195 |
T2196 |
amod |
small,phenotype |
R1308 |
T2196 |
T2197 |
npadvmod |
phenotype,related |
R1309 |
T2197 |
T2204 |
amod |
related,protein |
R1310 |
T2198 |
T2196 |
punct |
–,phenotype |
R1311 |
T2199 |
T2196 |
cc |
and,phenotype |
R1312 |
T2062 |
T2029 |
punct |
.,discovered |
R1313 |
T2200 |
T2196 |
conj |
mothers,phenotype |
R1314 |
T2201 |
T2200 |
prep |
against,mothers |
R1315 |
T2202 |
T2201 |
pobj |
decapentaplegic,against |
R1316 |
T2064 |
T2065 |
advmod |
Thereafter,disappears |
R1317 |
T2066 |
T2065 |
punct |
", ",disappears |
R1318 |
T2203 |
T2197 |
punct |
–,related |
R1319 |
T2204 |
T2191 |
conj |
protein,β2 |
R1320 |
T2067 |
T2065 |
nsubj |
Snail,disappears |
R1321 |
T2205 |
T2204 |
nummod |
2,protein |
R1322 |
T2206 |
T2204 |
punct |
(,protein |
R1323 |
T2207 |
T2204 |
appos |
SMAD2,protein |
R1324 |
T2068 |
T2065 |
cc |
and,disappears |
R1325 |
T2208 |
T2193 |
punct |
),signaling |
R1326 |
T2209 |
T2210 |
amod |
upstream,inducers |
R1327 |
T2069 |
T2065 |
conj |
remains,disappears |
R1328 |
T2210 |
T2189 |
attr |
inducers,are |
R1329 |
T2211 |
T2210 |
prep |
of,inducers |
R1330 |
T2212 |
T2213 |
compound |
Snail,expression |
R1331 |
T2070 |
T2069 |
acomp |
absent,remains |
R1332 |
T2213 |
T2211 |
pobj |
expression,of |
R1333 |
T2214 |
T2213 |
compound |
gene,expression |
R1334 |
T2071 |
T2069 |
prep |
during,remains |
R1335 |
T2215 |
T2189 |
prep |
in,are |
R1336 |
T2216 |
T2217 |
compound |
skin,epithelium |
R1337 |
T2072 |
T2073 |
amod |
subsequent,growth |
R1338 |
T2217 |
T2215 |
pobj |
epithelium,in |
R1339 |
T2218 |
T2170 |
punct |
.,provide |
R1340 |
T2073 |
T2071 |
pobj |
growth,during |
R1341 |
T2220 |
T2221 |
prep |
In,form |
R1342 |
T2074 |
T2073 |
nmod |
follicle,growth |
R1343 |
T2222 |
T2223 |
det |
the,absence |
R1344 |
T2223 |
T2220 |
pobj |
absence,In |
R1345 |
T2075 |
T2073 |
amod |
down,growth |
R1346 |
T2224 |
T2223 |
prep |
of,absence |
R1347 |
T2225 |
T2226 |
compound |
TGF,β2 |
R1348 |
T2226 |
T2228 |
compound |
β2,signaling |
R1349 |
T2076 |
T2073 |
punct |
-,growth |
R1350 |
T2227 |
T2226 |
punct |
-,β2 |
R1351 |
T2077 |
T2073 |
cc |
and,growth |
R1352 |
T2228 |
T2224 |
pobj |
signaling,of |
R1353 |
T2229 |
T2228 |
cc |
and,signaling |
R1354 |
T2230 |
T2231 |
compound |
Snail,expression |
R1355 |
T2078 |
T2073 |
conj |
maturation,growth |
R1356 |
T2231 |
T2228 |
conj |
expression,signaling |
R1357 |
T2232 |
T2231 |
compound |
gene,expression |
R1358 |
T2079 |
T2065 |
punct |
.,disappears |
R1359 |
T2233 |
T2221 |
punct |
", ",form |
R1360 |
T2234 |
T2235 |
compound |
hair,placodes |
R1361 |
T2235 |
T2221 |
nsubj |
placodes,form |
R1362 |
T2236 |
T2221 |
aux |
can,form |
R1363 |
T2237 |
T2221 |
punct |
", ",form |
R1364 |
T2238 |
T2221 |
cc |
but,form |
R1365 |
T2081 |
T2082 |
det |
This,pattern |
R1366 |
T2239 |
T2240 |
amod |
further,growth |
R1367 |
T2240 |
T2244 |
nsubjpass |
growth,blocked |
R1370 |
T2082 |
T2084 |
nsubj |
pattern,appears |
R1371 |
T2243 |
T2240 |
punct |
-,growth |
R1372 |
T2244 |
T2221 |
conj |
blocked,form |
R1373 |
T2245 |
T2244 |
auxpass |
is,blocked |
R1374 |
T2083 |
T2082 |
amod |
exquisite,pattern |
R1375 |
T2246 |
T2221 |
punct |
.,form |
R1376 |
T2085 |
T2086 |
aux |
to,be |
R1377 |
T2248 |
T2249 |
poss |
Our,studies |
R1378 |
T2249 |
T2250 |
nsubj |
studies,point |
R1379 |
T2251 |
T2250 |
prep |
to,point |
R1380 |
T2086 |
T2084 |
xcomp |
be,appears |
R1381 |
T2252 |
T2253 |
det |
the,view |
R1382 |
T2253 |
T2251 |
pobj |
view,to |
R1383 |
T2087 |
T2088 |
advmod |
functionally,relevant |
R1384 |
T2254 |
T2255 |
mark |
that,functions |
R1385 |
T2255 |
T2253 |
acl |
functions,view |
R1386 |
T2256 |
T2255 |
nsubj |
Snail,functions |
R1387 |
T2088 |
T2086 |
acomp |
relevant,be |
R1388 |
T2257 |
T2255 |
advmod |
likely,functions |
R1389 |
T2258 |
T2255 |
advmod |
downstream,functions |
R1390 |
T2259 |
T2258 |
prep |
of,downstream |
R1391 |
T2089 |
T2090 |
mark |
since,affects |
R1392 |
T2260 |
T2261 |
compound |
cell,fate |
R1393 |
T2261 |
T2262 |
compound |
fate,specification |
R1394 |
T2090 |
T2086 |
advcl |
affects,be |
R1395 |
T2262 |
T2259 |
pobj |
specification,of |
R1396 |
T2263 |
T2250 |
punct |
", ",point |
R1397 |
T2264 |
T2250 |
prep |
at,point |
R1398 |
T2091 |
T2090 |
csubj |
altering,affects |
R1399 |
T2265 |
T2266 |
det |
a,stage |
R1400 |
T2266 |
T2264 |
pobj |
stage,at |
R1401 |
T2092 |
T2091 |
dobj |
it,altering |
R1402 |
T2267 |
T2268 |
advmod |
where,begins |
R1403 |
T2268 |
T2266 |
relcl |
begins,stage |
R1404 |
T2093 |
T2094 |
advmod |
in,vivo |
R1405 |
T2269 |
T2270 |
det |
the,bud |
R1406 |
T2270 |
T2268 |
nsubj |
bud,begins |
R1407 |
T2094 |
T2091 |
advmod |
vivo,altering |
R1408 |
T2271 |
T2272 |
aux |
to,exhibit |
R1409 |
T2272 |
T2268 |
xcomp |
exhibit,begins |
R1410 |
T2273 |
T2274 |
amod |
enhanced,proliferation |
R1411 |
T2095 |
T2090 |
advmod |
correspondingly,affects |
R1412 |
T2274 |
T2272 |
dobj |
proliferation,exhibit |
R1413 |
T2275 |
T2274 |
cc |
and,proliferation |
R1414 |
T2276 |
T2274 |
conj |
migration,proliferation |
R1415 |
T2277 |
T2250 |
punct |
.,point |
R1416 |
T2096 |
T2090 |
dobj |
features,affects |
R1368 |
T2241 |
T2240 |
nmod |
follicle,growth |
R1369 |
T2242 |
T2240 |
amod |
down,growth |