PMC:539061 / 534-799 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/539061","sourcedb":"PMC","sourceid":"539061","source_url":"http://www.ncbi.nlm.nih.gov/pmc/539061","text":" involved. We found that transforming growth factor β2 signaling is necessary to transiently induce the transcription factor Snail and activate the Ras-mitogen-activated protein kinase (MAPK) pathway in the bud. In the epidermis, Snail misexpression leads to hyperp","tracks":[{"project":"craft-ca-core-dev","denotations":[{"id":"T77","span":{"begin":25,"end":54},"obj":"PR:000000183"},{"id":"T78","span":{"begin":125,"end":130},"obj":"PR:000015308"},{"id":"T79","span":{"begin":152,"end":159},"obj":"CHEBI:52290"},{"id":"T80","span":{"begin":219,"end":228},"obj":"UBERON:0007376"},{"id":"T81","span":{"begin":230,"end":235},"obj":"PR:000015308"},{"id":"T82","span":{"begin":239,"end":249},"obj":"GO:0010467"}],"attributes":[{"subj":"T77","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T78","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T79","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T80","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T81","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T82","pred":"source","obj":"craft-ca-core-dev"}]},{"project":"craft-ca-core-ex-dev","denotations":[{"id":"T108","span":{"begin":25,"end":54},"obj":"PR_EXT:000000183"},{"id":"T109","span":{"begin":38,"end":44},"obj":"GO_EXT:biological_growth_entity_or_process"},{"id":"T110","span":{"begin":38,"end":51},"obj":"GO_EXT:0008083"},{"id":"T111","span":{"begin":55,"end":64},"obj":"GO_EXT:cell_communication_or_signaling_or_signal_transduction"},{"id":"T112","span":{"begin":104,"end":117},"obj":"GO_EXT:transcription"},{"id":"T113","span":{"begin":104,"end":124},"obj":"GO_EXT:transcription_factor"},{"id":"T114","span":{"begin":125,"end":130},"obj":"PR_EXT:000015308"},{"id":"T115","span":{"begin":152,"end":159},"obj":"CHEBI_EXT:52290"},{"id":"T116","span":{"begin":152,"end":184},"obj":"GO_PR_EXT:MAP_kinase"},{"id":"T117","span":{"begin":170,"end":177},"obj":"CHEBI_PR_EXT:protein"},{"id":"T118","span":{"begin":186,"end":190},"obj":"GO_PR_EXT:MAP_kinase"},{"id":"T119","span":{"begin":219,"end":228},"obj":"UBERON:0007376"},{"id":"T120","span":{"begin":230,"end":235},"obj":"PR_EXT:000015308"},{"id":"T121","span":{"begin":239,"end":249},"obj":"GO:0010467"}],"attributes":[{"subj":"T108","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T109","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T110","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T111","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T112","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T113","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T114","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T115","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T116","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T117","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T118","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T119","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T120","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T121","pred":"source","obj":"craft-ca-core-ex-dev"}]},{"project":"craft-sa-dev","denotations":[{"id":"T225","span":{"begin":1,"end":9},"obj":"VBN"},{"id":"T226","span":{"begin":9,"end":10},"obj":"."},{"id":"T227","span":{"begin":10,"end":211},"obj":"sentence"},{"id":"T228","span":{"begin":11,"end":13},"obj":"PRP"},{"id":"T229","span":{"begin":14,"end":19},"obj":"VBD"},{"id":"T230","span":{"begin":20,"end":24},"obj":"IN"},{"id":"T231","span":{"begin":65,"end":67},"obj":"VBZ"},{"id":"T232","span":{"begin":25,"end":37},"obj":"VBG"},{"id":"T233","span":{"begin":38,"end":44},"obj":"NN"},{"id":"T234","span":{"begin":52,"end":54},"obj":"NN"},{"id":"T235","span":{"begin":45,"end":51},"obj":"NN"},{"id":"T236","span":{"begin":55,"end":64},"obj":"NN"},{"id":"T237","span":{"begin":68,"end":77},"obj":"JJ"},{"id":"T238","span":{"begin":78,"end":80},"obj":"TO"},{"id":"T239","span":{"begin":93,"end":99},"obj":"VB"},{"id":"T240","span":{"begin":81,"end":92},"obj":"RB"},{"id":"T241","span":{"begin":100,"end":103},"obj":"DT"},{"id":"T242","span":{"begin":125,"end":130},"obj":"NN"},{"id":"T243","span":{"begin":104,"end":117},"obj":"NN"},{"id":"T244","span":{"begin":118,"end":124},"obj":"NN"},{"id":"T245","span":{"begin":131,"end":134},"obj":"CC"},{"id":"T246","span":{"begin":135,"end":143},"obj":"VB"},{"id":"T247","span":{"begin":144,"end":147},"obj":"DT"},{"id":"T248","span":{"begin":192,"end":199},"obj":"NN"},{"id":"T249","span":{"begin":148,"end":151},"obj":"NN"},{"id":"T250","span":{"begin":178,"end":184},"obj":"NN"},{"id":"T251","span":{"begin":151,"end":152},"obj":"HYPH"},{"id":"T252","span":{"begin":152,"end":159},"obj":"NN"},{"id":"T253","span":{"begin":160,"end":169},"obj":"VBN"},{"id":"T254","span":{"begin":159,"end":160},"obj":"HYPH"},{"id":"T255","span":{"begin":170,"end":177},"obj":"NN"},{"id":"T256","span":{"begin":185,"end":186},"obj":"-LRB-"},{"id":"T257","span":{"begin":186,"end":190},"obj":"NN"},{"id":"T258","span":{"begin":190,"end":191},"obj":"-RRB-"},{"id":"T259","span":{"begin":200,"end":202},"obj":"IN"},{"id":"T260","span":{"begin":203,"end":206},"obj":"DT"},{"id":"T261","span":{"begin":207,"end":210},"obj":"NN"},{"id":"T262","span":{"begin":210,"end":211},"obj":"."},{"id":"T264","span":{"begin":212,"end":214},"obj":"IN"},{"id":"T265","span":{"begin":250,"end":255},"obj":"VBZ"},{"id":"T266","span":{"begin":215,"end":218},"obj":"DT"},{"id":"T267","span":{"begin":219,"end":228},"obj":"NN"},{"id":"T268","span":{"begin":228,"end":230},"obj":","},{"id":"T269","span":{"begin":230,"end":235},"obj":"NN"},{"id":"T270","span":{"begin":236,"end":249},"obj":"NN"},{"id":"T271","span":{"begin":256,"end":258},"obj":"IN"}],"relations":[{"id":"R77","pred":"ccomp","subj":"T231","obj":"T229"},{"id":"R78","pred":"csubj","subj":"T232","obj":"T231"},{"id":"R79","pred":"compound","subj":"T233","obj":"T234"},{"id":"R81","pred":"compound","subj":"T235","obj":"T234"},{"id":"R82","pred":"dobj","subj":"T236","obj":"T232"},{"id":"R85","pred":"advcl","subj":"T239","obj":"T231"},{"id":"R86","pred":"advmod","subj":"T240","obj":"T239"},{"id":"R88","pred":"dobj","subj":"T242","obj":"T239"},{"id":"R89","pred":"compound","subj":"T243","obj":"T242"},{"id":"R90","pred":"compound","subj":"T244","obj":"T242"},{"id":"R94","pred":"dobj","subj":"T248","obj":"T246"},{"id":"R95","pred":"nmod","subj":"T249","obj":"T250"},{"id":"R96","pred":"nmod","subj":"T250","obj":"T248"},{"id":"R97","pred":"punct","subj":"T251","obj":"T250"},{"id":"R98","pred":"npadvmod","subj":"T252","obj":"T253"},{"id":"R99","pred":"amod","subj":"T253","obj":"T250"},{"id":"R100","pred":"punct","subj":"T254","obj":"T253"},{"id":"R101","pred":"nmod","subj":"T255","obj":"T250"},{"id":"R102","pred":"punct","subj":"T256","obj":"T250"},{"id":"R103","pred":"appos","subj":"T257","obj":"T250"},{"id":"R104","pred":"punct","subj":"T258","obj":"T248"},{"id":"R75","pred":"nsubj","subj":"T228","obj":"T229"},{"id":"R76","pred":"mark","subj":"T230","obj":"T231"},{"id":"R80","pred":"compound","subj":"T234","obj":"T236"},{"id":"R83","pred":"acomp","subj":"T237","obj":"T231"},{"id":"R84","pred":"aux","subj":"T238","obj":"T239"},{"id":"R87","pred":"det","subj":"T241","obj":"T242"},{"id":"R91","pred":"cc","subj":"T245","obj":"T239"},{"id":"R92","pred":"conj","subj":"T246","obj":"T239"},{"id":"R93","pred":"det","subj":"T247","obj":"T248"},{"id":"R105","pred":"prep","subj":"T259","obj":"T246"},{"id":"R106","pred":"det","subj":"T260","obj":"T261"},{"id":"R107","pred":"pobj","subj":"T261","obj":"T259"},{"id":"R108","pred":"punct","subj":"T262","obj":"T229"},{"id":"R109","pred":"prep","subj":"T264","obj":"T265"},{"id":"R110","pred":"det","subj":"T266","obj":"T267"},{"id":"R111","pred":"pobj","subj":"T267","obj":"T264"},{"id":"R112","pred":"punct","subj":"T268","obj":"T265"},{"id":"R113","pred":"compound","subj":"T269","obj":"T270"},{"id":"R114","pred":"nsubj","subj":"T270","obj":"T265"},{"id":"R115","pred":"prep","subj":"T271","obj":"T265"}],"attributes":[{"subj":"T225","pred":"source","obj":"craft-sa-dev"},{"subj":"T226","pred":"source","obj":"craft-sa-dev"},{"subj":"T227","pred":"source","obj":"craft-sa-dev"},{"subj":"T228","pred":"source","obj":"craft-sa-dev"},{"subj":"T229","pred":"source","obj":"craft-sa-dev"},{"subj":"T230","pred":"source","obj":"craft-sa-dev"},{"subj":"T231","pred":"source","obj":"craft-sa-dev"},{"subj":"T232","pred":"source","obj":"craft-sa-dev"},{"subj":"T233","pred":"source","obj":"craft-sa-dev"},{"subj":"T234","pred":"source","obj":"craft-sa-dev"},{"subj":"T235","pred":"source","obj":"craft-sa-dev"},{"subj":"T236","pred":"source","obj":"craft-sa-dev"},{"subj":"T237","pred":"source","obj":"craft-sa-dev"},{"subj":"T238","pred":"source","obj":"craft-sa-dev"},{"subj":"T239","pred":"source","obj":"craft-sa-dev"},{"subj":"T240","pred":"source","obj":"craft-sa-dev"},{"subj":"T241","pred":"source","obj":"craft-sa-dev"},{"subj":"T242","pred":"source","obj":"craft-sa-dev"},{"subj":"T243","pred":"source","obj":"craft-sa-dev"},{"subj":"T244","pred":"source","obj":"craft-sa-dev"},{"subj":"T245","pred":"source","obj":"craft-sa-dev"},{"subj":"T246","pred":"source","obj":"craft-sa-dev"},{"subj":"T247","pred":"source","obj":"craft-sa-dev"},{"subj":"T248","pred":"source","obj":"craft-sa-dev"},{"subj":"T249","pred":"source","obj":"craft-sa-dev"},{"subj":"T250","pred":"source","obj":"craft-sa-dev"},{"subj":"T251","pred":"source","obj":"craft-sa-dev"},{"subj":"T252","pred":"source","obj":"craft-sa-dev"},{"subj":"T253","pred":"source","obj":"craft-sa-dev"},{"subj":"T254","pred":"source","obj":"craft-sa-dev"},{"subj":"T255","pred":"source","obj":"craft-sa-dev"},{"subj":"T256","pred":"source","obj":"craft-sa-dev"},{"subj":"T257","pred":"source","obj":"craft-sa-dev"},{"subj":"T258","pred":"source","obj":"craft-sa-dev"},{"subj":"T259","pred":"source","obj":"craft-sa-dev"},{"subj":"T260","pred":"source","obj":"craft-sa-dev"},{"subj":"T261","pred":"source","obj":"craft-sa-dev"},{"subj":"T262","pred":"source","obj":"craft-sa-dev"},{"subj":"T264","pred":"source","obj":"craft-sa-dev"},{"subj":"T265","pred":"source","obj":"craft-sa-dev"},{"subj":"T266","pred":"source","obj":"craft-sa-dev"},{"subj":"T267","pred":"source","obj":"craft-sa-dev"},{"subj":"T268","pred":"source","obj":"craft-sa-dev"},{"subj":"T269","pred":"source","obj":"craft-sa-dev"},{"subj":"T270","pred":"source","obj":"craft-sa-dev"},{"subj":"T271","pred":"source","obj":"craft-sa-dev"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"craft-ca-core-dev","color":"#ec93dc","default":true},{"id":"craft-ca-core-ex-dev","color":"#93ece1"},{"id":"craft-sa-dev","color":"#ecc793"}]}]}}