PMC:539061 / 47677-48502 JSONTXT

{"project":"craft-ca-core-dev","denotations":[{"id":"T9357","span":{"begin":0,"end":6},"obj":"PR:000000046"},{"id":"T9358","span":{"begin":42,"end":55},"obj":"CL:0000312"},{"id":"T9359","span":{"begin":65,"end":75},"obj":"GO:0007049"},{"id":"T9360","span":{"begin":94,"end":100},"obj":"PR:000000183"},{"id":"T9361","span":{"begin":152,"end":159},"obj":"GO:0040007"},{"id":"T9362","span":{"begin":176,"end":185},"obj":"_FRAGMENT"},{"id":"T9363","span":{"begin":196,"end":206},"obj":"GO:0044851"},{"id":"T9364","span":{"begin":190,"end":195},"obj":"UBERON:0007023"},{"id":"T9365","span":{"begin":196,"end":200},"obj":"UBERON:0001037"},{"id":"T9366","span":{"begin":323,"end":332},"obj":"GO:0006915"},{"id":"T9367","span":{"begin":388,"end":394},"obj":"PR:000000182"},{"id":"T9368","span":{"begin":433,"end":440},"obj":"GO:0040007"},{"id":"T9369","span":{"begin":454,"end":459},"obj":"GO:0007567"},{"id":"T9370","span":{"begin":460,"end":474},"obj":"UBERON:0002073"},{"id":"T9371","span":{"begin":476,"end":482},"obj":"PR:000000183"},{"id":"T9372","span":{"begin":505,"end":514},"obj":"UBERON:0000922"},{"id":"T9373","span":{"begin":598,"end":604},"obj":"PR:000000183"},{"id":"T9374","span":{"begin":607,"end":616},"obj":"UBERON:0000922"},{"id":"T9375","span":{"begin":617,"end":627},"obj":"GO:0010467"},{"id":"T9376","span":{"begin":656,"end":662},"obj":"PR:000000183"},{"id":"T9377","span":{"begin":818,"end":824},"obj":"PR:000000046"}],"relations":[{"id":"R5885","pred":"_lexicallyChainedTo","subj":"T9363","obj":"T9362"}],"text":"TGF-βs are known to promote withdrawal of keratinocytes from the cell cycle [41]. Hence, when TGF-β2 protein was detected at the transition between the growing and destructive phases of the adult hair cycle, research initially and naturally focused on a role for this family member in cessation of growth and/or triggering apoptosis ([42] and references therein). However, in contrast to TGF-β1-null skin, which exhibits an extended growing phase of postnatal hair follicles, TGF-β2-null skin displays an embryonic block in follicle bud progression [32]. Although this phenotype is consistent with TGF-β2's embryonic expression patterns [33], about 50% of TGF-β2 null buds appear unable to progress to the down-growth phase, a feature that cannot be explained readily on the basis of previously established effects of TGF-βs."}

{"project":"2_test","denotations":[{"id":"15630473-12809600-84810308","span":{"begin":77,"end":79},"obj":"12809600"},{"id":"15630473-14708594-84810309","span":{"begin":335,"end":337},"obj":"14708594"},{"id":"15630473-10433821-84810310","span":{"begin":550,"end":552},"obj":"10433821"},{"id":"15630473-1955457-84810311","span":{"begin":638,"end":640},"obj":"1955457"},{"id":"T44318","span":{"begin":77,"end":79},"obj":"12809600"},{"id":"T56843","span":{"begin":335,"end":337},"obj":"14708594"},{"id":"T14593","span":{"begin":550,"end":552},"obj":"10433821"},{"id":"T83401","span":{"begin":638,"end":640},"obj":"1955457"}],"text":"TGF-βs are known to promote withdrawal of keratinocytes from the cell cycle [41]. Hence, when TGF-β2 protein was detected at the transition between the growing and destructive phases of the adult hair cycle, research initially and naturally focused on a role for this family member in cessation of growth and/or triggering apoptosis ([42] and references therein). However, in contrast to TGF-β1-null skin, which exhibits an extended growing phase of postnatal hair follicles, TGF-β2-null skin displays an embryonic block in follicle bud progression [32]. Although this phenotype is consistent with TGF-β2's embryonic expression patterns [33], about 50% of TGF-β2 null buds appear unable to progress to the down-growth phase, a feature that cannot be explained readily on the basis of previously established effects of TGF-βs."}

{"project":"craft-ca-core-ex-dev","denotations":[{"id":"T9514","span":{"begin":0,"end":6},"obj":"PR_EXT:000000046"},{"id":"T9515","span":{"begin":42,"end":55},"obj":"CL:0000312"},{"id":"T9516","span":{"begin":65,"end":69},"obj":"CL_GO_EXT:cell"},{"id":"T9517","span":{"begin":65,"end":75},"obj":"GO:0007049"},{"id":"T9518","span":{"begin":94,"end":100},"obj":"PR_EXT:000000183"},{"id":"T9519","span":{"begin":101,"end":108},"obj":"CHEBI_PR_EXT:protein"},{"id":"T9520","span":{"begin":152,"end":159},"obj":"GO:0040007"},{"id":"T9521","span":{"begin":176,"end":185},"obj":"_FRAGMENT"},{"id":"T9522","span":{"begin":196,"end":206},"obj":"GO:0044851"},{"id":"T9523","span":{"begin":190,"end":195},"obj":"UBERON:0007023"},{"id":"T9524","span":{"begin":196,"end":200},"obj":"UBERON:0001037"},{"id":"T9525","span":{"begin":298,"end":304},"obj":"GO_EXT:biological_growth_entity_or_process"},{"id":"T9526","span":{"begin":323,"end":332},"obj":"GO:0006915"},{"id":"T9527","span":{"begin":388,"end":394},"obj":"PR_EXT:000000182"},{"id":"T9528","span":{"begin":395,"end":399},"obj":"SO_EXT:sequence_nullness"},{"id":"T9529","span":{"begin":400,"end":404},"obj":"UBERON_EXT:zone_of_skin_or_skin_of_body"},{"id":"T9530","span":{"begin":433,"end":440},"obj":"GO:0040007"},{"id":"T9531","span":{"begin":454,"end":459},"obj":"GO:0007567"},{"id":"T9532","span":{"begin":460,"end":474},"obj":"UBERON:0002073"},{"id":"T9533","span":{"begin":476,"end":482},"obj":"PR_EXT:000000183"},{"id":"T9534","span":{"begin":483,"end":487},"obj":"SO_EXT:sequence_nullness"},{"id":"T9535","span":{"begin":488,"end":492},"obj":"UBERON_EXT:zone_of_skin_or_skin_of_body"},{"id":"T9536","span":{"begin":505,"end":514},"obj":"UBERON:0000922"},{"id":"T9537","span":{"begin":524,"end":532},"obj":"UBERON_EXT:follicle"},{"id":"T9538","span":{"begin":598,"end":604},"obj":"PR_EXT:000000183"},{"id":"T9539","span":{"begin":607,"end":616},"obj":"UBERON:0000922"},{"id":"T9540","span":{"begin":617,"end":627},"obj":"GO:0010467"},{"id":"T9541","span":{"begin":656,"end":662},"obj":"PR_EXT:000000183"},{"id":"T9542","span":{"begin":663,"end":667},"obj":"SO_EXT:sequence_nullness"},{"id":"T9543","span":{"begin":711,"end":717},"obj":"GO_EXT:biological_growth_entity_or_process"},{"id":"T9544","span":{"begin":818,"end":824},"obj":"PR_EXT:000000046"}],"relations":[{"id":"R5890","pred":"_lexicallyChainedTo","subj":"T9522","obj":"T9521"}],"text":"TGF-βs are known to promote withdrawal of keratinocytes from the cell cycle [41]. Hence, when TGF-β2 protein was detected at the transition between the growing and destructive phases of the adult hair cycle, research initially and naturally focused on a role for this family member in cessation of growth and/or triggering apoptosis ([42] and references therein). However, in contrast to TGF-β1-null skin, which exhibits an extended growing phase of postnatal hair follicles, TGF-β2-null skin displays an embryonic block in follicle bud progression [32]. Although this phenotype is consistent with TGF-β2's embryonic expression patterns [33], about 50% of TGF-β2 null buds appear unable to progress to the down-growth phase, a feature that cannot be explained readily on the basis of previously established effects of TGF-βs."}

{"project":"craft-sa-dev","denotations":[{"id":"T9956","span":{"begin":0,"end":3},"obj":"NN"},{"id":"T9957","span":{"begin":4,"end":6},"obj":"NNS"},{"id":"T9958","span":{"begin":3,"end":4},"obj":"HYPH"},{"id":"T9959","span":{"begin":11,"end":16},"obj":"VBN"},{"id":"T9960","span":{"begin":7,"end":10},"obj":"VBP"},{"id":"T9961","span":{"begin":17,"end":19},"obj":"TO"},{"id":"T9963","span":{"begin":28,"end":38},"obj":"NN"},{"id":"T9964","span":{"begin":39,"end":41},"obj":"IN"},{"id":"T9965","span":{"begin":42,"end":55},"obj":"NNS"},{"id":"T9966","span":{"begin":56,"end":60},"obj":"IN"},{"id":"T9967","span":{"begin":61,"end":64},"obj":"DT"},{"id":"T9968","span":{"begin":70,"end":75},"obj":"NN"},{"id":"T9969","span":{"begin":65,"end":69},"obj":"NN"},{"id":"T9970","span":{"begin":76,"end":77},"obj":"-LRB-"},{"id":"T9971","span":{"begin":77,"end":79},"obj":"CD"},{"id":"T9972","span":{"begin":79,"end":80},"obj":"-RRB-"},{"id":"T9973","span":{"begin":80,"end":81},"obj":"."},{"id":"T9974","span":{"begin":81,"end":363},"obj":"sentence"},{"id":"T9975","span":{"begin":82,"end":87},"obj":"RB"},{"id":"T9976","span":{"begin":241,"end":248},"obj":"VBD"},{"id":"T9977","span":{"begin":87,"end":89},"obj":","},{"id":"T9978","span":{"begin":89,"end":93},"obj":"WRB"},{"id":"T9979","span":{"begin":113,"end":121},"obj":"VBN"},{"id":"T9980","span":{"begin":94,"end":97},"obj":"NN"},{"id":"T9981","span":{"begin":98,"end":100},"obj":"NN"},{"id":"T9982","span":{"begin":97,"end":98},"obj":"HYPH"},{"id":"T9983","span":{"begin":101,"end":108},"obj":"NN"},{"id":"T9984","span":{"begin":109,"end":112},"obj":"VBD"},{"id":"T9985","span":{"begin":122,"end":124},"obj":"IN"},{"id":"T9986","span":{"begin":125,"end":128},"obj":"DT"},{"id":"T9987","span":{"begin":129,"end":139},"obj":"NN"},{"id":"T9988","span":{"begin":140,"end":147},"obj":"IN"},{"id":"T9989","span":{"begin":148,"end":151},"obj":"DT"},{"id":"T9990","span":{"begin":176,"end":182},"obj":"NNS"},{"id":"T9991","span":{"begin":152,"end":159},"obj":"NN"},{"id":"T9992","span":{"begin":164,"end":175},"obj":"JJ"},{"id":"T9993","span":{"begin":160,"end":163},"obj":"CC"},{"id":"T9994","span":{"begin":183,"end":185},"obj":"IN"},{"id":"T9995","span":{"begin":186,"end":189},"obj":"DT"},{"id":"T9996","span":{"begin":201,"end":206},"obj":"NN"},{"id":"T9997","span":{"begin":190,"end":195},"obj":"JJ"},{"id":"T9998","span":{"begin":196,"end":200},"obj":"NN"},{"id":"T9999","span":{"begin":206,"end":208},"obj":","},{"id":"T10000","span":{"begin":208,"end":216},"obj":"NN"},{"id":"T10001","span":{"begin":217,"end":226},"obj":"RB"},{"id":"T10002","span":{"begin":227,"end":230},"obj":"CC"},{"id":"T10003","span":{"begin":231,"end":240},"obj":"RB"},{"id":"T10004","span":{"begin":249,"end":251},"obj":"IN"},{"id":"T10005","span":{"begin":252,"end":253},"obj":"DT"},{"id":"T10006","span":{"begin":254,"end":258},"obj":"NN"},{"id":"T10007","span":{"begin":259,"end":262},"obj":"IN"},{"id":"T10008","span":{"begin":263,"end":267},"obj":"DT"},{"id":"T10009","span":{"begin":275,"end":281},"obj":"NN"},{"id":"T10010","span":{"begin":268,"end":274},"obj":"NN"},{"id":"T10011","span":{"begin":282,"end":284},"obj":"IN"},{"id":"T10012","span":{"begin":285,"end":294},"obj":"NN"},{"id":"T10013","span":{"begin":295,"end":297},"obj":"IN"},{"id":"T10014","span":{"begin":298,"end":304},"obj":"NN"},{"id":"T10015","span":{"begin":305,"end":308},"obj":"CC"},{"id":"T10016","span":{"begin":308,"end":309},"obj":"HYPH"},{"id":"T10017","span":{"begin":309,"end":311},"obj":"CC"},{"id":"T10018","span":{"begin":312,"end":322},"obj":"VBG"},{"id":"T10019","span":{"begin":323,"end":332},"obj":"NN"},{"id":"T10020","span":{"begin":333,"end":334},"obj":"-LRB-"},{"id":"T10021","span":{"begin":335,"end":337},"obj":"CD"},{"id":"T10022","span":{"begin":334,"end":335},"obj":"-LRB-"},{"id":"T10023","span":{"begin":337,"end":338},"obj":"-RRB-"},{"id":"T10024","span":{"begin":339,"end":342},"obj":"CC"},{"id":"T10025","span":{"begin":343,"end":353},"obj":"NNS"},{"id":"T10026","span":{"begin":354,"end":361},"obj":"RB"},{"id":"T10027","span":{"begin":361,"end":362},"obj":"-RRB-"},{"id":"T10028","span":{"begin":362,"end":363},"obj":"."},{"id":"T10029","span":{"begin":363,"end":554},"obj":"sentence"},{"id":"T10030","span":{"begin":364,"end":371},"obj":"RB"},{"id":"T10031","span":{"begin":493,"end":501},"obj":"VBZ"},{"id":"T10032","span":{"begin":371,"end":373},"obj":","},{"id":"T10033","span":{"begin":373,"end":375},"obj":"IN"},{"id":"T10034","span":{"begin":376,"end":384},"obj":"NN"},{"id":"T10035","span":{"begin":385,"end":387},"obj":"IN"},{"id":"T10036","span":{"begin":388,"end":391},"obj":"NN"},{"id":"T10037","span":{"begin":392,"end":394},"obj":"NN"},{"id":"T10038","span":{"begin":391,"end":392},"obj":"HYPH"},{"id":"T10039","span":{"begin":395,"end":399},"obj":"JJ"},{"id":"T10040","span":{"begin":394,"end":395},"obj":"HYPH"},{"id":"T10041","span":{"begin":400,"end":404},"obj":"NN"},{"id":"T10042","span":{"begin":404,"end":406},"obj":","},{"id":"T10043","span":{"begin":406,"end":411},"obj":"WDT"},{"id":"T10044","span":{"begin":412,"end":420},"obj":"VBZ"},{"id":"T10045","span":{"begin":421,"end":423},"obj":"DT"},{"id":"T10046","span":{"begin":441,"end":446},"obj":"NN"},{"id":"T10047","span":{"begin":424,"end":432},"obj":"JJ"},{"id":"T10048","span":{"begin":433,"end":440},"obj":"NN"},{"id":"T10049","span":{"begin":447,"end":449},"obj":"IN"},{"id":"T10050","span":{"begin":450,"end":459},"obj":"JJ"},{"id":"T10051","span":{"begin":465,"end":474},"obj":"NNS"},{"id":"T10052","span":{"begin":460,"end":464},"obj":"NN"},{"id":"T10053","span":{"begin":474,"end":476},"obj":","},{"id":"T10054","span":{"begin":476,"end":479},"obj":"NN"},{"id":"T10055","span":{"begin":480,"end":482},"obj":"NN"},{"id":"T10056","span":{"begin":479,"end":480},"obj":"HYPH"},{"id":"T10057","span":{"begin":483,"end":487},"obj":"JJ"},{"id":"T10058","span":{"begin":482,"end":483},"obj":"HYPH"},{"id":"T10059","span":{"begin":488,"end":492},"obj":"NN"},{"id":"T10060","span":{"begin":502,"end":504},"obj":"DT"},{"id":"T10061","span":{"begin":515,"end":520},"obj":"NN"},{"id":"T10062","span":{"begin":505,"end":514},"obj":"JJ"},{"id":"T10063","span":{"begin":521,"end":523},"obj":"IN"},{"id":"T10064","span":{"begin":524,"end":532},"obj":"NN"},{"id":"T10065","span":{"begin":533,"end":536},"obj":"NN"},{"id":"T10066","span":{"begin":537,"end":548},"obj":"NN"},{"id":"T10067","span":{"begin":549,"end":550},"obj":"-LRB-"},{"id":"T10068","span":{"begin":550,"end":552},"obj":"CD"},{"id":"T10069","span":{"begin":552,"end":553},"obj":"-RRB-"},{"id":"T10070","span":{"begin":553,"end":554},"obj":"."},{"id":"T10071","span":{"begin":554,"end":825},"obj":"sentence"},{"id":"T10072","span":{"begin":555,"end":563},"obj":"IN"},{"id":"T10073","span":{"begin":579,"end":581},"obj":"VBZ"},{"id":"T10074","span":{"begin":564,"end":568},"obj":"DT"},{"id":"T10075","span":{"begin":569,"end":578},"obj":"NN"},{"id":"T10076","span":{"begin":673,"end":679},"obj":"VBP"},{"id":"T10077","span":{"begin":582,"end":592},"obj":"JJ"},{"id":"T10078","span":{"begin":593,"end":597},"obj":"IN"},{"id":"T10079","span":{"begin":598,"end":601},"obj":"NN"},{"id":"T10080","span":{"begin":602,"end":604},"obj":"NN"},{"id":"T10081","span":{"begin":601,"end":602},"obj":"HYPH"},{"id":"T10082","span":{"begin":628,"end":636},"obj":"NNS"},{"id":"T10083","span":{"begin":604,"end":606},"obj":"POS"},{"id":"T10084","span":{"begin":607,"end":616},"obj":"JJ"},{"id":"T10085","span":{"begin":617,"end":627},"obj":"NN"},{"id":"T10086","span":{"begin":637,"end":638},"obj":"-LRB-"},{"id":"T10087","span":{"begin":638,"end":640},"obj":"CD"},{"id":"T10088","span":{"begin":640,"end":641},"obj":"-RRB-"},{"id":"T10089","span":{"begin":641,"end":643},"obj":","},{"id":"T10090","span":{"begin":643,"end":648},"obj":"IN"},{"id":"T10091","span":{"begin":649,"end":651},"obj":"CD"},{"id":"T10092","span":{"begin":651,"end":652},"obj":"NN"},{"id":"T10093","span":{"begin":653,"end":655},"obj":"IN"},{"id":"T10094","span":{"begin":656,"end":659},"obj":"NN"},{"id":"T10095","span":{"begin":660,"end":662},"obj":"NN"},{"id":"T10096","span":{"begin":659,"end":660},"obj":"HYPH"},{"id":"T10097","span":{"begin":663,"end":667},"obj":"JJ"},{"id":"T10098","span":{"begin":668,"end":672},"obj":"NNS"},{"id":"T10099","span":{"begin":680,"end":686},"obj":"JJ"},{"id":"T10100","span":{"begin":687,"end":689},"obj":"TO"},{"id":"T10101","span":{"begin":690,"end":698},"obj":"VB"},{"id":"T10102","span":{"begin":699,"end":701},"obj":"IN"},{"id":"T10103","span":{"begin":702,"end":705},"obj":"DT"},{"id":"T10104","span":{"begin":718,"end":723},"obj":"NN"},{"id":"T10105","span":{"begin":706,"end":710},"obj":"JJ"},{"id":"T10106","span":{"begin":711,"end":717},"obj":"NN"},{"id":"T10107","span":{"begin":710,"end":711},"obj":"HYPH"},{"id":"T10108","span":{"begin":723,"end":725},"obj":","},{"id":"T10109","span":{"begin":725,"end":726},"obj":"DT"},{"id":"T10110","span":{"begin":727,"end":734},"obj":"NN"},{"id":"T10111","span":{"begin":735,"end":739},"obj":"WDT"},{"id":"T10112","span":{"begin":750,"end":759},"obj":"VBN"},{"id":"T10113","span":{"begin":740,"end":743},"obj":"MD"},{"id":"T10114","span":{"begin":743,"end":746},"obj":"RB"},{"id":"T10115","span":{"begin":747,"end":749},"obj":"VB"},{"id":"T10116","span":{"begin":760,"end":767},"obj":"RB"},{"id":"T10117","span":{"begin":768,"end":770},"obj":"IN"},{"id":"T10118","span":{"begin":771,"end":774},"obj":"DT"},{"id":"T10119","span":{"begin":775,"end":780},"obj":"NN"},{"id":"T10120","span":{"begin":781,"end":783},"obj":"IN"},{"id":"T10121","span":{"begin":784,"end":794},"obj":"RB"},{"id":"T10122","span":{"begin":795,"end":806},"obj":"VBN"},{"id":"T10123","span":{"begin":807,"end":814},"obj":"NNS"},{"id":"T10124","span":{"begin":815,"end":817},"obj":"IN"},{"id":"T10125","span":{"begin":818,"end":821},"obj":"NN"},{"id":"T10126","span":{"begin":822,"end":824},"obj":"NNS"},{"id":"T10127","span":{"begin":821,"end":822},"obj":"HYPH"},{"id":"T10128","span":{"begin":824,"end":825},"obj":"."},{"id":"T9962","span":{"begin":20,"end":27},"obj":"VB"}],"relations":[{"id":"R6182","pred":"compound","subj":"T9956","obj":"T9957"},{"id":"R6183","pred":"nsubjpass","subj":"T9957","obj":"T9959"},{"id":"R6184","pred":"punct","subj":"T9958","obj":"T9957"},{"id":"R6185","pred":"auxpass","subj":"T9960","obj":"T9959"},{"id":"R6186","pred":"aux","subj":"T9961","obj":"T9962"},{"id":"R6187","pred":"xcomp","subj":"T9962","obj":"T9959"},{"id":"R6188","pred":"dobj","subj":"T9963","obj":"T9962"},{"id":"R6189","pred":"prep","subj":"T9964","obj":"T9963"},{"id":"R6190","pred":"pobj","subj":"T9965","obj":"T9964"},{"id":"R6191","pred":"prep","subj":"T9966","obj":"T9963"},{"id":"R6192","pred":"det","subj":"T9967","obj":"T9968"},{"id":"R6193","pred":"pobj","subj":"T9968","obj":"T9966"},{"id":"R6194","pred":"compound","subj":"T9969","obj":"T9968"},{"id":"R6195","pred":"punct","subj":"T9970","obj":"T9971"},{"id":"R6196","pred":"parataxis","subj":"T9971","obj":"T9959"},{"id":"R6197","pred":"punct","subj":"T9972","obj":"T9971"},{"id":"R6198","pred":"punct","subj":"T9973","obj":"T9959"},{"id":"R6199","pred":"advmod","subj":"T9975","obj":"T9976"},{"id":"R6200","pred":"punct","subj":"T9977","obj":"T9976"},{"id":"R6201","pred":"advmod","subj":"T9978","obj":"T9979"},{"id":"R6202","pred":"advcl","subj":"T9979","obj":"T9976"},{"id":"R6203","pred":"compound","subj":"T9980","obj":"T9981"},{"id":"R6204","pred":"compound","subj":"T9981","obj":"T9983"},{"id":"R6205","pred":"punct","subj":"T9982","obj":"T9981"},{"id":"R6206","pred":"nsubjpass","subj":"T9983","obj":"T9979"},{"id":"R6207","pred":"auxpass","subj":"T9984","obj":"T9979"},{"id":"R6208","pred":"prep","subj":"T9985","obj":"T9979"},{"id":"R6209","pred":"det","subj":"T9986","obj":"T9987"},{"id":"R6210","pred":"pobj","subj":"T9987","obj":"T9985"},{"id":"R6211","pred":"prep","subj":"T9988","obj":"T9987"},{"id":"R6212","pred":"det","subj":"T9989","obj":"T9990"},{"id":"R6213","pred":"pobj","subj":"T9990","obj":"T9988"},{"id":"R6214","pred":"npadvmod","subj":"T9991","obj":"T9992"},{"id":"R6215","pred":"amod","subj":"T9992","obj":"T9990"},{"id":"R6216","pred":"cc","subj":"T9993","obj":"T9992"},{"id":"R6217","pred":"prep","subj":"T9994","obj":"T9990"},{"id":"R6218","pred":"det","subj":"T9995","obj":"T9996"},{"id":"R6219","pred":"pobj","subj":"T9996","obj":"T9994"},{"id":"R6220","pred":"amod","subj":"T9997","obj":"T9996"},{"id":"R6221","pred":"compound","subj":"T9998","obj":"T9996"},{"id":"R6222","pred":"punct","subj":"T9999","obj":"T9976"},{"id":"R6223","pred":"nsubj","subj":"T10000","obj":"T9976"},{"id":"R6224","pred":"advmod","subj":"T10001","obj":"T9976"},{"id":"R6225","pred":"cc","subj":"T10002","obj":"T10001"},{"id":"R6226","pred":"conj","subj":"T10003","obj":"T10001"},{"id":"R6227","pred":"prep","subj":"T10004","obj":"T9976"},{"id":"R6228","pred":"det","subj":"T10005","obj":"T10006"},{"id":"R6229","pred":"pobj","subj":"T10006","obj":"T10004"},{"id":"R6230","pred":"prep","subj":"T10007","obj":"T10006"},{"id":"R6231","pred":"det","subj":"T10008","obj":"T10009"},{"id":"R6232","pred":"pobj","subj":"T10009","obj":"T10007"},{"id":"R6233","pred":"compound","subj":"T10010","obj":"T10009"},{"id":"R6234","pred":"prep","subj":"T10011","obj":"T10006"},{"id":"R6235","pred":"pobj","subj":"T10012","obj":"T10011"},{"id":"R6236","pred":"prep","subj":"T10013","obj":"T10012"},{"id":"R6237","pred":"pobj","subj":"T10014","obj":"T10013"},{"id":"R6238","pred":"cc","subj":"T10015","obj":"T10012"},{"id":"R6239","pred":"punct","subj":"T10016","obj":"T10015"},{"id":"R6240","pred":"cc","subj":"T10017","obj":"T10015"},{"id":"R6241","pred":"conj","subj":"T10018","obj":"T10012"},{"id":"R6242","pred":"dobj","subj":"T10019","obj":"T10018"},{"id":"R6243","pred":"punct","subj":"T10020","obj":"T10021"},{"id":"R6244","pred":"parataxis","subj":"T10021","obj":"T9976"},{"id":"R6245","pred":"punct","subj":"T10022","obj":"T10021"},{"id":"R6246","pred":"punct","subj":"T10023","obj":"T10021"},{"id":"R6247","pred":"cc","subj":"T10024","obj":"T10021"},{"id":"R6248","pred":"conj","subj":"T10025","obj":"T10021"},{"id":"R6249","pred":"advmod","subj":"T10026","obj":"T10025"},{"id":"R6250","pred":"punct","subj":"T10027","obj":"T10021"},{"id":"R6251","pred":"punct","subj":"T10028","obj":"T9976"},{"id":"R6252","pred":"advmod","subj":"T10030","obj":"T10031"},{"id":"R6253","pred":"punct","subj":"T10032","obj":"T10031"},{"id":"R6254","pred":"prep","subj":"T10033","obj":"T10031"},{"id":"R6255","pred":"pobj","subj":"T10034","obj":"T10033"},{"id":"R6256","pred":"prep","subj":"T10035","obj":"T10034"},{"id":"R6257","pred":"compound","subj":"T10036","obj":"T10037"},{"id":"R6258","pred":"npadvmod","subj":"T10037","obj":"T10039"},{"id":"R6259","pred":"punct","subj":"T10038","obj":"T10037"},{"id":"R6260","pred":"amod","subj":"T10039","obj":"T10041"},{"id":"R6261","pred":"punct","subj":"T10040","obj":"T10039"},{"id":"R6262","pred":"pobj","subj":"T10041","obj":"T10035"},{"id":"R6263","pred":"punct","subj":"T10042","obj":"T10041"},{"id":"R6264","pred":"dep","subj":"T10043","obj":"T10044"},{"id":"R6265","pred":"relcl","subj":"T10044","obj":"T10041"},{"id":"R6266","pred":"det","subj":"T10045","obj":"T10046"},{"id":"R6267","pred":"dobj","subj":"T10046","obj":"T10044"},{"id":"R6268","pred":"amod","subj":"T10047","obj":"T10046"},{"id":"R6269","pred":"compound","subj":"T10048","obj":"T10046"},{"id":"R6270","pred":"prep","subj":"T10049","obj":"T10046"},{"id":"R6271","pred":"amod","subj":"T10050","obj":"T10051"},{"id":"R6272","pred":"pobj","subj":"T10051","obj":"T10049"},{"id":"R6273","pred":"compound","subj":"T10052","obj":"T10051"},{"id":"R6274","pred":"punct","subj":"T10053","obj":"T10031"},{"id":"R6275","pred":"compound","subj":"T10054","obj":"T10055"},{"id":"R6276","pred":"npadvmod","subj":"T10055","obj":"T10057"},{"id":"R6277","pred":"punct","subj":"T10056","obj":"T10055"},{"id":"R6278","pred":"amod","subj":"T10057","obj":"T10059"},{"id":"R6279","pred":"punct","subj":"T10058","obj":"T10057"},{"id":"R6280","pred":"nsubj","subj":"T10059","obj":"T10031"},{"id":"R6281","pred":"det","subj":"T10060","obj":"T10061"},{"id":"R6282","pred":"dobj","subj":"T10061","obj":"T10031"},{"id":"R6283","pred":"amod","subj":"T10062","obj":"T10061"},{"id":"R6284","pred":"prep","subj":"T10063","obj":"T10061"},{"id":"R6285","pred":"compound","subj":"T10064","obj":"T10065"},{"id":"R6286","pred":"compound","subj":"T10065","obj":"T10066"},{"id":"R6287","pred":"pobj","subj":"T10066","obj":"T10063"},{"id":"R6288","pred":"punct","subj":"T10067","obj":"T10068"},{"id":"R6289","pred":"parataxis","subj":"T10068","obj":"T10031"},{"id":"R6290","pred":"punct","subj":"T10069","obj":"T10068"},{"id":"R6291","pred":"punct","subj":"T10070","obj":"T10031"},{"id":"R6292","pred":"mark","subj":"T10072","obj":"T10073"},{"id":"R6293","pred":"advcl","subj":"T10073","obj":"T10076"},{"id":"R6294","pred":"det","subj":"T10074","obj":"T10075"},{"id":"R6295","pred":"nsubj","subj":"T10075","obj":"T10073"},{"id":"R6296","pred":"acomp","subj":"T10077","obj":"T10073"},{"id":"R6297","pred":"prep","subj":"T10078","obj":"T10077"},{"id":"R6298","pred":"compound","subj":"T10079","obj":"T10080"},{"id":"R6299","pred":"poss","subj":"T10080","obj":"T10082"},{"id":"R6300","pred":"punct","subj":"T10081","obj":"T10080"},{"id":"R6301","pred":"pobj","subj":"T10082","obj":"T10078"},{"id":"R6302","pred":"case","subj":"T10083","obj":"T10080"},{"id":"R6303","pred":"amod","subj":"T10084","obj":"T10082"},{"id":"R6304","pred":"compound","subj":"T10085","obj":"T10082"},{"id":"R6305","pred":"punct","subj":"T10086","obj":"T10087"},{"id":"R6306","pred":"parataxis","subj":"T10087","obj":"T10073"},{"id":"R6307","pred":"punct","subj":"T10088","obj":"T10087"},{"id":"R6308","pred":"punct","subj":"T10089","obj":"T10076"},{"id":"R6309","pred":"quantmod","subj":"T10090","obj":"T10091"},{"id":"R6310","pred":"nummod","subj":"T10091","obj":"T10092"},{"id":"R6311","pred":"nsubj","subj":"T10092","obj":"T10076"},{"id":"R6312","pred":"prep","subj":"T10093","obj":"T10092"},{"id":"R6313","pred":"compound","subj":"T10094","obj":"T10095"},{"id":"R6314","pred":"npadvmod","subj":"T10095","obj":"T10097"},{"id":"R6315","pred":"punct","subj":"T10096","obj":"T10095"},{"id":"R6316","pred":"amod","subj":"T10097","obj":"T10098"},{"id":"R6317","pred":"pobj","subj":"T10098","obj":"T10093"},{"id":"R6318","pred":"oprd","subj":"T10099","obj":"T10076"},{"id":"R6319","pred":"aux","subj":"T10100","obj":"T10101"},{"id":"R6320","pred":"xcomp","subj":"T10101","obj":"T10099"},{"id":"R6321","pred":"prep","subj":"T10102","obj":"T10101"},{"id":"R6322","pred":"det","subj":"T10103","obj":"T10104"},{"id":"R6323","pred":"pobj","subj":"T10104","obj":"T10102"},{"id":"R6324","pred":"amod","subj":"T10105","obj":"T10106"},{"id":"R6325","pred":"compound","subj":"T10106","obj":"T10104"},{"id":"R6326","pred":"punct","subj":"T10107","obj":"T10106"},{"id":"R6327","pred":"punct","subj":"T10108","obj":"T10099"},{"id":"R6328","pred":"det","subj":"T10109","obj":"T10110"},{"id":"R6329","pred":"npadvmod","subj":"T10110","obj":"T10099"},{"id":"R6330","pred":"dep","subj":"T10111","obj":"T10112"},{"id":"R6331","pred":"relcl","subj":"T10112","obj":"T10110"},{"id":"R6332","pred":"aux","subj":"T10113","obj":"T10112"},{"id":"R6333","pred":"neg","subj":"T10114","obj":"T10112"},{"id":"R6334","pred":"auxpass","subj":"T10115","obj":"T10112"},{"id":"R6335","pred":"advmod","subj":"T10116","obj":"T10112"},{"id":"R6336","pred":"prep","subj":"T10117","obj":"T10112"},{"id":"R6337","pred":"det","subj":"T10118","obj":"T10119"},{"id":"R6338","pred":"pobj","subj":"T10119","obj":"T10117"},{"id":"R6339","pred":"prep","subj":"T10120","obj":"T10119"},{"id":"R6340","pred":"advmod","subj":"T10121","obj":"T10122"},{"id":"R6341","pred":"amod","subj":"T10122","obj":"T10123"},{"id":"R6342","pred":"pobj","subj":"T10123","obj":"T10120"},{"id":"R6343","pred":"prep","subj":"T10124","obj":"T10123"},{"id":"R6344","pred":"compound","subj":"T10125","obj":"T10126"},{"id":"R6345","pred":"pobj","subj":"T10126","obj":"T10124"},{"id":"R6346","pred":"punct","subj":"T10127","obj":"T10126"},{"id":"R6347","pred":"punct","subj":"T10128","obj":"T10076"}],"text":"TGF-βs are known to promote withdrawal of keratinocytes from the cell cycle [41]. Hence, when TGF-β2 protein was detected at the transition between the growing and destructive phases of the adult hair cycle, research initially and naturally focused on a role for this family member in cessation of growth and/or triggering apoptosis ([42] and references therein). However, in contrast to TGF-β1-null skin, which exhibits an extended growing phase of postnatal hair follicles, TGF-β2-null skin displays an embryonic block in follicle bud progression [32]. Although this phenotype is consistent with TGF-β2's embryonic expression patterns [33], about 50% of TGF-β2 null buds appear unable to progress to the down-growth phase, a feature that cannot be explained readily on the basis of previously established effects of TGF-βs."}