Id |
Subject |
Object |
Predicate |
Lexical cue |
T7954 |
0-3 |
DT |
denotes |
The |
T7955 |
10-18 |
NNS |
denotes |
kinetics |
T7956 |
4-9 |
JJ |
denotes |
rapid |
T7957 |
44-53 |
VBN |
denotes |
reflected |
T7958 |
19-21 |
IN |
denotes |
of |
T7959 |
22-27 |
NN |
denotes |
Snail |
T7960 |
28-38 |
NN |
denotes |
expression |
T7961 |
39-43 |
VBD |
denotes |
were |
T7962 |
54-56 |
IN |
denotes |
at |
T7963 |
57-60 |
DT |
denotes |
the |
T7964 |
66-71 |
NN |
denotes |
level |
T7965 |
61-65 |
NN |
denotes |
mRNA |
T7966 |
71-73 |
, |
denotes |
, |
T7967 |
73-83 |
VBG |
denotes |
suggesting |
T7968 |
84-88 |
IN |
denotes |
that |
T7969 |
136-138 |
VB |
denotes |
be |
T7970 |
89-94 |
NN |
denotes |
Snail |
T7971 |
95-103 |
NN |
denotes |
promoter |
T7972 |
104-112 |
NN |
denotes |
activity |
T7973 |
113-115 |
IN |
denotes |
in |
T7974 |
116-129 |
NNS |
denotes |
keratinocytes |
T7975 |
130-135 |
MD |
denotes |
might |
T7976 |
139-148 |
JJ |
denotes |
sensitive |
T7977 |
149-151 |
IN |
denotes |
to |
T7978 |
152-155 |
NN |
denotes |
TGF |
T7979 |
156-158 |
NN |
denotes |
β2 |
T7980 |
155-156 |
HYPH |
denotes |
- |
T7981 |
159-168 |
NN |
denotes |
signaling |
T7982 |
169-170 |
-LRB- |
denotes |
( |
T7983 |
177-179 |
NN |
denotes |
5C |
T7984 |
170-176 |
NN |
denotes |
Figure |
T7985 |
179-180 |
-RRB- |
denotes |
) |
T7986 |
180-181 |
. |
denotes |
. |
T7987 |
181-408 |
sentence |
denotes |
To test this possibility, we engineered a transgene driving the β-galactosidase reporter under the control of approximately 2.2 kb of promoter sequence located 5′ from the transcription initiation site of the mouse Snail gene. |
T7988 |
182-184 |
TO |
denotes |
To |
T7989 |
185-189 |
VB |
denotes |
test |
T7990 |
211-221 |
VBD |
denotes |
engineered |
T7991 |
190-194 |
DT |
denotes |
this |
T7992 |
195-206 |
NN |
denotes |
possibility |
T7993 |
206-208 |
, |
denotes |
, |
T7994 |
208-210 |
PRP |
denotes |
we |
T7995 |
222-223 |
DT |
denotes |
a |
T7996 |
224-233 |
NN |
denotes |
transgene |
T7997 |
234-241 |
VBG |
denotes |
driving |
T7998 |
242-245 |
DT |
denotes |
the |
T7999 |
262-270 |
NN |
denotes |
reporter |
T8000 |
246-247 |
NN |
denotes |
β |
T8001 |
248-261 |
NN |
denotes |
galactosidase |
T8002 |
247-248 |
HYPH |
denotes |
- |
T8003 |
271-276 |
IN |
denotes |
under |
T8004 |
277-280 |
DT |
denotes |
the |
T8005 |
281-288 |
NN |
denotes |
control |
T8006 |
289-291 |
IN |
denotes |
of |
T8007 |
292-305 |
RB |
denotes |
approximately |
T8008 |
306-309 |
CD |
denotes |
2.2 |
T8009 |
310-312 |
NN |
denotes |
kb |
T8010 |
313-315 |
IN |
denotes |
of |
T8011 |
316-324 |
NN |
denotes |
promoter |
T8012 |
325-333 |
NN |
denotes |
sequence |
T8013 |
334-341 |
VBN |
denotes |
located |
T8014 |
342-343 |
CD |
denotes |
5 |
T8015 |
343-344 |
SYM |
denotes |
′ |
T8016 |
345-349 |
IN |
denotes |
from |
T8017 |
350-353 |
DT |
denotes |
the |
T8018 |
379-383 |
NN |
denotes |
site |
T8019 |
354-367 |
NN |
denotes |
transcription |
T8020 |
368-378 |
NN |
denotes |
initiation |
T8021 |
384-386 |
IN |
denotes |
of |
T8022 |
387-390 |
DT |
denotes |
the |
T8023 |
403-407 |
NN |
denotes |
gene |
T8024 |
391-396 |
NN |
denotes |
mouse |
T8025 |
397-402 |
NN |
denotes |
Snail |
T8026 |
407-408 |
. |
denotes |
. |
T8027 |
408-608 |
sentence |
denotes |
At 2 d after transient transfection, keratinocytes were treated with TGF-β2 (t = 0) and then assayed for transgene activity over the same time course in which we had observed Snail protein induction. |
T8028 |
409-411 |
IN |
denotes |
At |
T8029 |
465-472 |
VBN |
denotes |
treated |
T8030 |
412-413 |
CD |
denotes |
2 |
T8031 |
414-415 |
NN |
denotes |
d |
T8032 |
416-421 |
IN |
denotes |
after |
T8033 |
422-431 |
JJ |
denotes |
transient |
T8034 |
432-444 |
NN |
denotes |
transfection |
T8035 |
444-446 |
, |
denotes |
, |
T8036 |
446-459 |
NNS |
denotes |
keratinocytes |
T8037 |
460-464 |
VBD |
denotes |
were |
T8038 |
473-477 |
IN |
denotes |
with |
T8039 |
478-481 |
NN |
denotes |
TGF |
T8040 |
482-484 |
NN |
denotes |
β2 |
T8041 |
481-482 |
HYPH |
denotes |
- |
T8042 |
485-486 |
-LRB- |
denotes |
( |
T8043 |
490-491 |
CD |
denotes |
0 |
T8044 |
486-487 |
NN |
denotes |
t |
T8045 |
488-489 |
SYM |
denotes |
= |
T8046 |
491-492 |
-RRB- |
denotes |
) |
T8047 |
493-496 |
CC |
denotes |
and |
T8048 |
497-501 |
RB |
denotes |
then |
T8049 |
502-509 |
VBN |
denotes |
assayed |
T8050 |
510-513 |
IN |
denotes |
for |
T8051 |
514-523 |
NN |
denotes |
transgene |
T8052 |
524-532 |
NN |
denotes |
activity |
T8053 |
533-537 |
IN |
denotes |
over |
T8054 |
538-541 |
DT |
denotes |
the |
T8055 |
552-558 |
NN |
denotes |
course |
T8056 |
542-546 |
JJ |
denotes |
same |
T8057 |
547-551 |
NN |
denotes |
time |
T8058 |
559-561 |
IN |
denotes |
in |
T8059 |
575-583 |
VBN |
denotes |
observed |
T8060 |
562-567 |
WDT |
denotes |
which |
T8061 |
568-570 |
PRP |
denotes |
we |
T8062 |
571-574 |
VBD |
denotes |
had |
T8063 |
584-589 |
NN |
denotes |
Snail |
T8064 |
590-597 |
NN |
denotes |
protein |
T8065 |
598-607 |
NN |
denotes |
induction |
T8066 |
607-608 |
. |
denotes |
. |
T8067 |
608-667 |
sentence |
denotes |
The results of this experiment are presented in Figure 5D. |
T8068 |
609-612 |
DT |
denotes |
The |
T8069 |
613-620 |
NNS |
denotes |
results |
T8070 |
644-653 |
VBN |
denotes |
presented |
T8071 |
621-623 |
IN |
denotes |
of |
T8072 |
624-628 |
DT |
denotes |
this |
T8073 |
629-639 |
NN |
denotes |
experiment |
T8074 |
640-643 |
VBP |
denotes |
are |
T8075 |
654-656 |
IN |
denotes |
in |
T8076 |
657-663 |
NN |
denotes |
Figure |
T8077 |
664-666 |
NN |
denotes |
5D |
T8078 |
666-667 |
. |
denotes |
. |
R4736 |
T7954 |
T7955 |
det |
The,kinetics |
R4737 |
T7955 |
T7957 |
nsubjpass |
kinetics,reflected |
R4738 |
T7956 |
T7955 |
amod |
rapid,kinetics |
R4739 |
T7958 |
T7955 |
prep |
of,kinetics |
R4740 |
T7959 |
T7960 |
compound |
Snail,expression |
R4741 |
T7960 |
T7958 |
pobj |
expression,of |
R4742 |
T7961 |
T7957 |
auxpass |
were,reflected |
R4743 |
T7962 |
T7957 |
prep |
at,reflected |
R4744 |
T7963 |
T7964 |
det |
the,level |
R4745 |
T7964 |
T7962 |
pobj |
level,at |
R4746 |
T7965 |
T7964 |
compound |
mRNA,level |
R4747 |
T7966 |
T7957 |
punct |
", ",reflected |
R4748 |
T7967 |
T7957 |
advcl |
suggesting,reflected |
R4749 |
T7968 |
T7969 |
mark |
that,be |
R4750 |
T7969 |
T7967 |
ccomp |
be,suggesting |
R4751 |
T7970 |
T7971 |
compound |
Snail,promoter |
R4752 |
T7971 |
T7972 |
compound |
promoter,activity |
R4753 |
T7972 |
T7969 |
nsubj |
activity,be |
R4754 |
T7973 |
T7972 |
prep |
in,activity |
R4755 |
T7974 |
T7973 |
pobj |
keratinocytes,in |
R4756 |
T7975 |
T7969 |
aux |
might,be |
R4757 |
T7976 |
T7969 |
acomp |
sensitive,be |
R4758 |
T7977 |
T7976 |
prep |
to,sensitive |
R4759 |
T7978 |
T7979 |
compound |
TGF,β2 |
R4760 |
T7979 |
T7981 |
compound |
β2,signaling |
R4761 |
T7980 |
T7979 |
punct |
-,β2 |
R4762 |
T7981 |
T7977 |
pobj |
signaling,to |
R4763 |
T7982 |
T7983 |
punct |
(,5C |
R4764 |
T7983 |
T7957 |
parataxis |
5C,reflected |
R4765 |
T7984 |
T7983 |
compound |
Figure,5C |
R4766 |
T7985 |
T7983 |
punct |
),5C |
R4767 |
T7986 |
T7957 |
punct |
.,reflected |
R4768 |
T7988 |
T7989 |
aux |
To,test |
R4769 |
T7989 |
T7990 |
advcl |
test,engineered |
R4770 |
T7991 |
T7992 |
det |
this,possibility |
R4771 |
T7992 |
T7989 |
dobj |
possibility,test |
R4772 |
T7993 |
T7990 |
punct |
", ",engineered |
R4773 |
T7994 |
T7990 |
nsubj |
we,engineered |
R4774 |
T7995 |
T7996 |
det |
a,transgene |
R4775 |
T7996 |
T7990 |
dobj |
transgene,engineered |
R4776 |
T7997 |
T7996 |
acl |
driving,transgene |
R4777 |
T7998 |
T7999 |
det |
the,reporter |
R4778 |
T7999 |
T7997 |
dobj |
reporter,driving |
R4779 |
T8000 |
T8001 |
compound |
β,galactosidase |
R4780 |
T8001 |
T7999 |
compound |
galactosidase,reporter |
R4781 |
T8002 |
T8001 |
punct |
-,galactosidase |
R4782 |
T8003 |
T7997 |
prep |
under,driving |
R4783 |
T8004 |
T8005 |
det |
the,control |
R4784 |
T8005 |
T8003 |
pobj |
control,under |
R4785 |
T8006 |
T8005 |
prep |
of,control |
R4786 |
T8007 |
T8008 |
advmod |
approximately,2.2 |
R4787 |
T8008 |
T8009 |
nummod |
2.2,kb |
R4788 |
T8009 |
T8006 |
pobj |
kb,of |
R4789 |
T8010 |
T8009 |
prep |
of,kb |
R4790 |
T8011 |
T8012 |
compound |
promoter,sequence |
R4791 |
T8012 |
T8010 |
pobj |
sequence,of |
R4792 |
T8013 |
T8012 |
acl |
located,sequence |
R4793 |
T8014 |
T8013 |
npadvmod |
5,located |
R4794 |
T8015 |
T8014 |
punct |
′,5 |
R4795 |
T8016 |
T8014 |
prep |
from,5 |
R4796 |
T8017 |
T8018 |
det |
the,site |
R4797 |
T8018 |
T8016 |
pobj |
site,from |
R4798 |
T8019 |
T8018 |
compound |
transcription,site |
R4799 |
T8020 |
T8018 |
compound |
initiation,site |
R4800 |
T8021 |
T8018 |
prep |
of,site |
R4801 |
T8022 |
T8023 |
det |
the,gene |
R4802 |
T8023 |
T8021 |
pobj |
gene,of |
R4803 |
T8024 |
T8023 |
compound |
mouse,gene |
R4804 |
T8025 |
T8023 |
compound |
Snail,gene |
R4805 |
T8026 |
T7990 |
punct |
.,engineered |
R4806 |
T8028 |
T8029 |
prep |
At,treated |
R4807 |
T8030 |
T8031 |
nummod |
2,d |
R4808 |
T8031 |
T8028 |
pobj |
d,At |
R4809 |
T8032 |
T8031 |
prep |
after,d |
R4810 |
T8033 |
T8034 |
amod |
transient,transfection |
R4811 |
T8034 |
T8032 |
pobj |
transfection,after |
R4812 |
T8035 |
T8029 |
punct |
", ",treated |
R4813 |
T8036 |
T8029 |
nsubjpass |
keratinocytes,treated |
R4814 |
T8037 |
T8029 |
auxpass |
were,treated |
R4815 |
T8038 |
T8029 |
prep |
with,treated |
R4816 |
T8039 |
T8040 |
compound |
TGF,β2 |
R4817 |
T8040 |
T8038 |
pobj |
β2,with |
R4818 |
T8041 |
T8040 |
punct |
-,β2 |
R4819 |
T8042 |
T8043 |
punct |
(,0 |
R4820 |
T8043 |
T8029 |
parataxis |
0,treated |
R4821 |
T8044 |
T8043 |
nsubj |
t,0 |
R4822 |
T8045 |
T8043 |
punct |
=,0 |
R4823 |
T8046 |
T8043 |
punct |
),0 |
R4824 |
T8047 |
T8029 |
cc |
and,treated |
R4825 |
T8048 |
T8049 |
advmod |
then,assayed |
R4826 |
T8049 |
T8029 |
conj |
assayed,treated |
R4827 |
T8050 |
T8049 |
prep |
for,assayed |
R4828 |
T8051 |
T8052 |
compound |
transgene,activity |
R4829 |
T8052 |
T8050 |
pobj |
activity,for |
R4830 |
T8053 |
T8049 |
prep |
over,assayed |
R4831 |
T8054 |
T8055 |
det |
the,course |
R4832 |
T8055 |
T8053 |
pobj |
course,over |
R4833 |
T8056 |
T8055 |
amod |
same,course |
R4834 |
T8057 |
T8055 |
compound |
time,course |
R4835 |
T8058 |
T8059 |
prep |
in,observed |
R4836 |
T8059 |
T8055 |
relcl |
observed,course |
R4837 |
T8060 |
T8058 |
pobj |
which,in |
R4838 |
T8061 |
T8059 |
nsubj |
we,observed |
R4839 |
T8062 |
T8059 |
aux |
had,observed |
R4840 |
T8063 |
T8064 |
compound |
Snail,protein |
R4841 |
T8064 |
T8065 |
compound |
protein,induction |
R4842 |
T8065 |
T8059 |
dobj |
induction,observed |
R4843 |
T8066 |
T8029 |
punct |
.,treated |
R4844 |
T8068 |
T8069 |
det |
The,results |
R4845 |
T8069 |
T8070 |
nsubjpass |
results,presented |
R4846 |
T8071 |
T8069 |
prep |
of,results |
R4847 |
T8072 |
T8073 |
det |
this,experiment |
R4848 |
T8073 |
T8071 |
pobj |
experiment,of |
R4849 |
T8074 |
T8070 |
auxpass |
are,presented |
R4850 |
T8075 |
T8070 |
prep |
in,presented |
R4851 |
T8076 |
T8077 |
compound |
Figure,5D |
R4852 |
T8077 |
T8075 |
pobj |
5D,in |
R4853 |
T8078 |
T8070 |
punct |
.,presented |