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PMC:539061 / 2275-3073
Annnotations
craft-ca-core-dev
Below, discontinuous spans are shown in the chain model. You can change it to the bag model.
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T589 | 64-89 | PR:000000034 | denotes | bone morphogenic proteins |
T590 | 91-95 | PR:000000034 | denotes | BMPs |
T591 | 98-127 | PR:000000046 | denotes | transforming growth factor βs |
T592 | 129-135 | PR:000000046 | denotes | TGF-βs |
T593 | 142-152 | CL:0000057 | denotes | fibroblast |
T594 | 198-210 | GO:0009986 | denotes | cell surface |
T595 | 216-224 | GO:0016020 | denotes | membrane |
T596 | 242-250 | GO:0005576 | denotes | external |
T597 | 251-270 | CHEBI:62488 | denotes | signaling molecules |
T598 | 288-320 | GO:0035556 | denotes | cascades of intracellular events |
T599 | 300-313 | GO:0005622 | denotes | intracellular |
T600 | 350-354 | SO:0000704 | denotes | gene |
T601 | 350-365 | GO:0010467 | denotes | gene expression |
T602 | 512-525 | GO:0009653 | denotes | morphogenetic |
T603 | 727-736 | CHEBI:35224 | denotes | effectors |
2_test
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
15630473-11841536-84810235 | 396-397 | 11841536 | denotes | 2 |
T26441 | 396-397 | 11841536 | denotes | 2 |
craft-ca-core-ex-dev
Below, discontinuous spans are shown in the chain model. You can change it to the bag model.
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T769 | 21-30 | CHEBI_EXT:polyatomic_entity_or_group | denotes | molecular |
T770 | 31-53 | GO_EXT:cell_communication_or_signaling_or_signal_transduction | denotes | communication pathways |
T771 | 64-68 | UBERON_EXT:bone_element_or_tissue | denotes | bone |
T772 | 64-89 | PR_EXT:000000034 | denotes | bone morphogenic proteins |
T773 | 69-80 | GO_EXT:0016015 | denotes | morphogenic |
T774 | 81-89 | CHEBI_PR_EXT:protein | denotes | proteins |
T775 | 91-95 | PR_EXT:000000034 | denotes | BMPs |
T776 | 98-127 | PR_EXT:000000046 | denotes | transforming growth factor βs |
T777 | 111-117 | GO_EXT:biological_growth_entity_or_process | denotes | growth |
T778 | 111-124 | GO_EXT:0008083 | denotes | growth factor |
T779 | 129-135 | PR_EXT:000000046 | denotes | TGF-βs |
T780 | 142-152 | CL:0000057 | denotes | fibroblast |
T781 | 153-159 | GO_EXT:biological_growth_entity_or_process | denotes | growth |
T782 | 153-167 | GO_EXT:0008083 | denotes | growth factors |
T783 | 198-202 | CL_GO_EXT:cell | denotes | cell |
T784 | 198-210 | GO:0009986 | denotes | cell surface |
T785 | 216-224 | GO:0016020 | denotes | membrane |
T786 | 225-234 | GO_EXT:0004872 | denotes | receptors |
T787 | 242-250 | GO:0005576 | denotes | external |
T788 | 251-260 | GO_EXT:cell_communication_or_signaling_or_signal_transduction | denotes | signaling |
T789 | 251-270 | CHEBI_EXT:62488 | denotes | signaling molecules |
T790 | 288-320 | GO:0035556 | denotes | cascades of intracellular events |
T791 | 300-313 | GO:0005622 | denotes | intracellular |
T792 | 305-313 | CL_GO_EXT:cell | denotes | cellular |
T793 | 350-354 | SO_EXT:0000704 | denotes | gene |
T794 | 350-365 | GO:0010467 | denotes | gene expression |
T795 | 367-373 | GO_EXT:biological_growth_entity_or_process | denotes | growth |
T796 | 379-394 | GO_RO_EXT:developmental_differentiation_process | denotes | differentiation |
T797 | 512-525 | GO:0009653 | denotes | morphogenetic |
T798 | 608-617 | GO_PATO_EXT:biological_patterning_process_or_quality | denotes | patterned |
T799 | 727-736 | CHEBI_EXT:35224 | denotes | effectors |
T800 | 773-777 | CL_GO_EXT:cell | denotes | cell |
craft-sa-dev
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1128 | 0-2 | IN | denotes | At |
T1129 | 54-57 | VBP | denotes | are |
T1130 | 3-6 | DT | denotes | the |
T1131 | 7-11 | NN | denotes | helm |
T1132 | 12-14 | IN | denotes | of |
T1133 | 15-20 | DT | denotes | these |
T1134 | 45-53 | NNS | denotes | pathways |
T1135 | 21-30 | JJ | denotes | molecular |
T1136 | 31-44 | NN | denotes | communication |
T1137 | 58-62 | NNS | denotes | Wnts |
T1138 | 62-64 | , | denotes | , |
T1139 | 64-68 | NN | denotes | bone |
T1140 | 81-89 | NN | denotes | proteins |
T1141 | 69-80 | JJ | denotes | morphogenic |
T1142 | 90-91 | -LRB- | denotes | ( |
T1143 | 91-95 | NNS | denotes | BMPs |
T1144 | 95-96 | -RRB- | denotes | ) |
T1145 | 96-98 | , | denotes | , |
T1146 | 98-110 | VBG | denotes | transforming |
T1147 | 125-127 | NNS | denotes | βs |
T1148 | 111-117 | NN | denotes | growth |
T1149 | 118-124 | NN | denotes | factor |
T1150 | 128-129 | -LRB- | denotes | ( |
T1151 | 129-132 | NN | denotes | TGF |
T1152 | 133-135 | NNS | denotes | βs |
T1153 | 132-133 | HYPH | denotes | - |
T1154 | 135-136 | -RRB- | denotes | ) |
T1155 | 136-138 | , | denotes | , |
T1156 | 138-141 | CC | denotes | and |
T1157 | 142-152 | NN | denotes | fibroblast |
T1158 | 160-167 | NNS | denotes | factors |
T1159 | 153-159 | NN | denotes | growth |
T1160 | 168-169 | -LRB- | denotes | ( |
T1161 | 169-173 | NNS | denotes | FGFs |
T1162 | 173-174 | -RRB- | denotes | ) |
T1163 | 174-175 | . | denotes | . |
T1164 | 175-399 | sentence | denotes | Through activation of cell surface transmembrane receptors, these external signaling molecules trigger distinct cascades of intracellular events that culminate in changes in gene expression, growth, and differentiation [2]. |
T1165 | 176-183 | IN | denotes | Through |
T1166 | 271-278 | VBP | denotes | trigger |
T1167 | 184-194 | NN | denotes | activation |
T1168 | 195-197 | IN | denotes | of |
T1169 | 198-202 | NN | denotes | cell |
T1170 | 203-210 | NN | denotes | surface |
T1171 | 225-234 | NNS | denotes | receptors |
T1172 | 211-224 | NN | denotes | transmembrane |
T1173 | 234-236 | , | denotes | , |
T1174 | 236-241 | DT | denotes | these |
T1175 | 261-270 | NNS | denotes | molecules |
T1176 | 242-250 | JJ | denotes | external |
T1177 | 251-260 | NN | denotes | signaling |
T1178 | 279-287 | JJ | denotes | distinct |
T1179 | 288-296 | NNS | denotes | cascades |
T1180 | 297-299 | IN | denotes | of |
T1181 | 300-313 | JJ | denotes | intracellular |
T1182 | 314-320 | NNS | denotes | events |
T1183 | 321-325 | WDT | denotes | that |
T1184 | 326-335 | VBP | denotes | culminate |
T1185 | 336-338 | IN | denotes | in |
T1186 | 339-346 | NNS | denotes | changes |
T1187 | 347-349 | IN | denotes | in |
T1188 | 350-354 | NN | denotes | gene |
T1189 | 355-365 | NN | denotes | expression |
T1190 | 365-367 | , | denotes | , |
T1191 | 367-373 | NN | denotes | growth |
T1192 | 373-375 | , | denotes | , |
T1193 | 375-378 | CC | denotes | and |
T1194 | 379-394 | NN | denotes | differentiation |
T1195 | 395-396 | -LRB- | denotes | [ |
T1196 | 396-397 | CD | denotes | 2 |
T1197 | 397-398 | -RRB- | denotes | ] |
T1198 | 398-399 | . | denotes | . |
T1199 | 399-572 | sentence | denotes | How this constellation of signals collaborates in tailoring each budding process so that it executes a distinct morphogenetic program has yet to be comprehensively defined. |
T1200 | 400-403 | WRB | denotes | How |
T1201 | 434-446 | VBZ | denotes | collaborates |
T1202 | 404-408 | DT | denotes | this |
T1203 | 409-422 | NN | denotes | constellation |
T1204 | 423-425 | IN | denotes | of |
T1205 | 426-433 | NNS | denotes | signals |
T1206 | 534-537 | VBZ | denotes | has |
T1207 | 447-449 | IN | denotes | in |
T1208 | 450-459 | VBG | denotes | tailoring |
T1209 | 460-464 | DT | denotes | each |
T1210 | 473-480 | NN | denotes | process |
T1211 | 465-472 | NN | denotes | budding |
T1212 | 481-483 | IN | denotes | so |
T1213 | 492-500 | VBZ | denotes | executes |
T1214 | 484-488 | IN | denotes | that |
T1215 | 489-491 | PRP | denotes | it |
T1216 | 501-502 | DT | denotes | a |
T1217 | 526-533 | NN | denotes | program |
T1218 | 503-511 | JJ | denotes | distinct |
T1219 | 512-525 | JJ | denotes | morphogenetic |
T1220 | 538-541 | RB | denotes | yet |
T1221 | 564-571 | VBN | denotes | defined |
T1222 | 542-544 | TO | denotes | to |
T1223 | 545-547 | VB | denotes | be |
T1224 | 548-563 | RB | denotes | comprehensively |
T1225 | 571-572 | . | denotes | . |
T1226 | 572-798 | sentence | denotes | However, the process appears to be patterned at the initial stages of bud formation, since the relative importance of these pathways and their downstream effectors differ as buds begin to develop and cell fates are specified. |
T1227 | 573-580 | RB | denotes | However |
T1228 | 594-601 | VBZ | denotes | appears |
T1229 | 580-582 | , | denotes | , |
T1230 | 582-585 | DT | denotes | the |
T1231 | 586-593 | NN | denotes | process |
T1232 | 602-604 | TO | denotes | to |
T1233 | 608-617 | VBN | denotes | patterned |
T1234 | 605-607 | VB | denotes | be |
T1235 | 618-620 | IN | denotes | at |
T1236 | 621-624 | DT | denotes | the |
T1237 | 633-639 | NNS | denotes | stages |
T1238 | 625-632 | JJ | denotes | initial |
T1239 | 640-642 | IN | denotes | of |
T1240 | 643-646 | NN | denotes | bud |
T1241 | 647-656 | NN | denotes | formation |
T1242 | 656-658 | , | denotes | , |
T1243 | 658-663 | IN | denotes | since |
T1244 | 737-743 | VBP | denotes | differ |
T1245 | 664-667 | DT | denotes | the |
T1246 | 677-687 | NN | denotes | importance |
T1247 | 668-676 | JJ | denotes | relative |
T1248 | 688-690 | IN | denotes | of |
T1249 | 691-696 | DT | denotes | these |
T1250 | 697-705 | NNS | denotes | pathways |
T1251 | 706-709 | CC | denotes | and |
T1252 | 710-715 | PRP$ | denotes | their |
T1253 | 727-736 | NNS | denotes | effectors |
T1254 | 716-726 | JJ | denotes | downstream |
T1255 | 744-746 | IN | denotes | as |
T1256 | 752-757 | VBP | denotes | begin |
T1257 | 747-751 | NNS | denotes | buds |
T1258 | 758-760 | TO | denotes | to |
T1259 | 761-768 | VB | denotes | develop |
T1260 | 769-772 | CC | denotes | and |
T1261 | 773-777 | NN | denotes | cell |
T1262 | 778-783 | NNS | denotes | fates |
T1263 | 788-797 | VBN | denotes | specified |
T1264 | 784-787 | VBP | denotes | are |
T1265 | 797-798 | . | denotes | . |
R328 | T1128 | T1129 | prep | At,are |
R329 | T1130 | T1131 | det | the,helm |
R330 | T1131 | T1128 | pobj | helm,At |
R331 | T1132 | T1131 | prep | of,helm |
R332 | T1133 | T1134 | det | these,pathways |
R333 | T1134 | T1132 | pobj | pathways,of |
R334 | T1135 | T1136 | amod | molecular,communication |
R335 | T1136 | T1134 | compound | communication,pathways |
R336 | T1137 | T1129 | nsubj | Wnts,are |
R337 | T1138 | T1137 | punct | ", ",Wnts |
R338 | T1139 | T1140 | nmod | bone,proteins |
R339 | T1140 | T1137 | appos | proteins,Wnts |
R340 | T1141 | T1140 | amod | morphogenic,proteins |
R341 | T1142 | T1140 | punct | (,proteins |
R342 | T1143 | T1140 | appos | BMPs,proteins |
R343 | T1144 | T1137 | punct | ),Wnts |
R344 | T1145 | T1137 | punct | ", ",Wnts |
R345 | T1146 | T1147 | amod | transforming,βs |
R346 | T1147 | T1137 | appos | βs,Wnts |
R347 | T1148 | T1147 | compound | growth,βs |
R348 | T1149 | T1147 | compound | factor,βs |
R349 | T1150 | T1147 | punct | (,βs |
R350 | T1151 | T1152 | compound | TGF,βs |
R351 | T1152 | T1147 | appos | βs,βs |
R352 | T1153 | T1152 | punct | -,βs |
R353 | T1154 | T1137 | punct | ),Wnts |
R354 | T1155 | T1137 | punct | ", ",Wnts |
R355 | T1156 | T1137 | cc | and,Wnts |
R356 | T1157 | T1158 | compound | fibroblast,factors |
R357 | T1158 | T1137 | conj | factors,Wnts |
R358 | T1159 | T1158 | compound | growth,factors |
R359 | T1160 | T1158 | punct | (,factors |
R360 | T1161 | T1158 | appos | FGFs,factors |
R361 | T1162 | T1129 | punct | ),are |
R362 | T1163 | T1129 | punct | .,are |
R363 | T1165 | T1166 | prep | Through,trigger |
R364 | T1167 | T1165 | pobj | activation,Through |
R365 | T1168 | T1167 | prep | of,activation |
R366 | T1169 | T1170 | compound | cell,surface |
R367 | T1170 | T1171 | compound | surface,receptors |
R368 | T1171 | T1168 | pobj | receptors,of |
R369 | T1172 | T1171 | compound | transmembrane,receptors |
R370 | T1173 | T1166 | punct | ", ",trigger |
R371 | T1174 | T1175 | det | these,molecules |
R372 | T1175 | T1166 | nsubj | molecules,trigger |
R373 | T1176 | T1175 | amod | external,molecules |
R374 | T1177 | T1175 | compound | signaling,molecules |
R375 | T1178 | T1179 | amod | distinct,cascades |
R376 | T1179 | T1166 | dobj | cascades,trigger |
R377 | T1180 | T1179 | prep | of,cascades |
R378 | T1181 | T1182 | amod | intracellular,events |
R379 | T1182 | T1180 | pobj | events,of |
R380 | T1183 | T1184 | dep | that,culminate |
R381 | T1184 | T1179 | relcl | culminate,cascades |
R382 | T1185 | T1184 | prep | in,culminate |
R383 | T1186 | T1185 | pobj | changes,in |
R384 | T1187 | T1186 | prep | in,changes |
R385 | T1188 | T1189 | compound | gene,expression |
R386 | T1189 | T1187 | pobj | expression,in |
R387 | T1190 | T1189 | punct | ", ",expression |
R388 | T1191 | T1189 | conj | growth,expression |
R389 | T1192 | T1191 | punct | ", ",growth |
R390 | T1193 | T1191 | cc | and,growth |
R391 | T1194 | T1191 | conj | differentiation,growth |
R392 | T1195 | T1196 | punct | [,2 |
R393 | T1196 | T1166 | parataxis | 2,trigger |
R394 | T1197 | T1196 | punct | ],2 |
R395 | T1198 | T1166 | punct | .,trigger |
R396 | T1200 | T1201 | advmod | How,collaborates |
R397 | T1201 | T1206 | csubj | collaborates,has |
R398 | T1202 | T1203 | det | this,constellation |
R399 | T1203 | T1201 | nsubj | constellation,collaborates |
R400 | T1204 | T1203 | prep | of,constellation |
R401 | T1205 | T1204 | pobj | signals,of |
R402 | T1207 | T1201 | prep | in,collaborates |
R403 | T1208 | T1207 | pcomp | tailoring,in |
R404 | T1209 | T1210 | det | each,process |
R405 | T1210 | T1208 | dobj | process,tailoring |
R406 | T1211 | T1210 | compound | budding,process |
R407 | T1212 | T1213 | mark | so,executes |
R408 | T1213 | T1208 | advcl | executes,tailoring |
R409 | T1214 | T1213 | mark | that,executes |
R410 | T1215 | T1213 | nsubj | it,executes |
R411 | T1216 | T1217 | det | a,program |
R412 | T1217 | T1213 | dobj | program,executes |
R413 | T1218 | T1217 | amod | distinct,program |
R414 | T1219 | T1217 | amod | morphogenetic,program |
R415 | T1220 | T1221 | advmod | yet,defined |
R416 | T1221 | T1206 | xcomp | defined,has |
R417 | T1222 | T1221 | aux | to,defined |
R418 | T1223 | T1221 | auxpass | be,defined |
R419 | T1224 | T1221 | advmod | comprehensively,defined |
R420 | T1225 | T1206 | punct | .,has |
R421 | T1227 | T1228 | advmod | However,appears |
R422 | T1229 | T1228 | punct | ", ",appears |
R423 | T1230 | T1231 | det | the,process |
R424 | T1231 | T1228 | nsubj | process,appears |
R425 | T1232 | T1233 | aux | to,patterned |
R426 | T1233 | T1228 | xcomp | patterned,appears |
R427 | T1234 | T1233 | auxpass | be,patterned |
R428 | T1235 | T1233 | prep | at,patterned |
R429 | T1236 | T1237 | det | the,stages |
R430 | T1237 | T1235 | pobj | stages,at |
R431 | T1238 | T1237 | amod | initial,stages |
R432 | T1239 | T1237 | prep | of,stages |
R433 | T1240 | T1241 | compound | bud,formation |
R434 | T1241 | T1239 | pobj | formation,of |
R435 | T1242 | T1228 | punct | ", ",appears |
R436 | T1243 | T1244 | mark | since,differ |
R437 | T1244 | T1228 | advcl | differ,appears |
R438 | T1245 | T1246 | det | the,importance |
R439 | T1246 | T1244 | nsubj | importance,differ |
R440 | T1247 | T1246 | amod | relative,importance |
R441 | T1248 | T1246 | prep | of,importance |
R442 | T1249 | T1250 | det | these,pathways |
R443 | T1250 | T1248 | pobj | pathways,of |
R444 | T1251 | T1250 | cc | and,pathways |
R445 | T1252 | T1253 | poss | their,effectors |
R446 | T1253 | T1250 | conj | effectors,pathways |
R447 | T1254 | T1253 | amod | downstream,effectors |
R448 | T1255 | T1256 | mark | as,begin |
R449 | T1256 | T1244 | advcl | begin,differ |
R450 | T1257 | T1256 | nsubj | buds,begin |
R451 | T1258 | T1259 | aux | to,develop |
R452 | T1259 | T1256 | xcomp | develop,begin |
R453 | T1260 | T1256 | cc | and,begin |
R454 | T1261 | T1262 | compound | cell,fates |
R455 | T1262 | T1263 | nsubjpass | fates,specified |
R456 | T1263 | T1256 | conj | specified,begin |
R457 | T1264 | T1263 | auxpass | are,specified |
R458 | T1265 | T1228 | punct | .,appears |