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PMC:529315 / 13614-16450 JSONTXT

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craft-ca-core-ex-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T7777 28-32 PR_EXT:000011459 denotes NT-3
T7778 43-58 GO_EXT:0042056 denotes chemoattractant
T7779 63-70 GO_EXT:detection_or_sensing_of_stimulus denotes sensory
T7780 71-76 GO:0030424 denotes axons
T7781 120-134 GO:0019230 denotes Proprioceptive
T7782 135-140 GO:0030424 denotes axons
T7841 2021-2024 CHEBI:52029 denotes DiI
T7783 144-148 NCBITaxon:10088 denotes mice
T7784 159-170 UBERON:0002315 denotes gray matter
T7785 178-189 UBERON:0002240 denotes spinal cord
T7786 228-235 UBERON:0009571 denotes midline
T7787 257-262 GO_EXT:biological_movement_or_translocation_process denotes motor
T7788 257-270 CL:0000100 denotes motor neurons
T7789 318-326 CHEBI_PR_EXT:collagen denotes collagen
T7790 340-342 SO_EXT:wild_type_entity_or_quality denotes WT
T7791 343-346 UBERON:0000044 denotes DRG
T7792 361-365 PR_EXT:000011459 denotes NT-3
T7793 434-440 NCBITaxon:27592 denotes bovine
T7794 441-446 UBERON:0001977 denotes serum
T7795 441-454 PR_EXT:000003918 denotes serum albumin
T7796 465-474 CHEBI_EXT:phosphate denotes phosphate
T7797 475-481 CHEBI_CHMO_EXT:buffer_solution denotes buffer
T7798 482-488 CHEBI_EXT:saline_solution denotes saline
T7799 518-521 UBERON:0000044 denotes DRG
T7800 522-527 GO:0030424 denotes axons
T7801 556-565 GO_PATO_EXT:biological_localization_process_or_quality denotes localized
T7802 566-570 PR_EXT:000011459 denotes NT-3
T7803 642-657 GO:0050918 denotes chemoattraction
T7804 817-821 PR_EXT:000011459 denotes NT-3
T7805 830-833 PR_EXT:000002193 denotes Bax
T7806 834-838 SO_EXT:sequence_nullness denotes null
T7807 839-846 UBERON:0000045 denotes ganglia
T7808 866-881 GO:0050918 denotes chemoattraction
T7809 903-907 PR_EXT:000011459 denotes NT-3
T7810 931-935 PR_EXT:000011471 denotes TrkC
T7811 944-950 PR_EXT:000001405 denotes p75NTR
T7812 996-999 UBERON:0000044 denotes DRG
T7813 1022-1028 PR_EXT:000001405 denotes p75NTR
T7814 1032-1036 NCBITaxon:10088 denotes mice
T7815 1047-1052 GO:0030424 denotes Axons
T7816 1062-1069 UBERON:0000045 denotes ganglia
T7817 1089-1104 GO:0050918 denotes chemoattraction
T7818 1117-1121 PR_EXT:000011459 denotes NT-3
T7819 1169-1173 PR_EXT:000011471 denotes TrkC
T7820 1174-1183 GO_EXT:0004872 denotes receptors
T7821 1184-1194 MOP:0000779 denotes conjugated
T7822 1198-1201 GO:0071735 denotes IgG
T7823 1220-1224 PR_EXT:000011471 denotes TrkC
T7824 1276-1280 PR_EXT:000011459 denotes NT-3
T7825 1290-1298 CHEBI_PR_EXT:collagen denotes collagen
T7826 1336-1340 PR_EXT:000011471 denotes TrkC
T7827 1348-1363 GO:0050918 denotes chemoattraction
T7828 1441-1445 PR_EXT:000011459 denotes NT-3
T7829 1537-1539 SO_EXT:wild_type_entity_or_quality denotes WT
T7830 1544-1548 UBERON:0000044 denotes DRGs
T7831 1603-1610 UBERON:0000045 denotes ganglia
T7832 1663-1669 GO_EXT:biological_growth_entity_or_process denotes growth
T7833 1752-1757 GO:0030424 denotes axons
T7834 1776-1782 GO_EXT:biological_growth_entity_or_process denotes growth
T7835 1823-1826 UBERON:0000044 denotes DRG
T7836 1827-1838 UBERON:0002240 denotes spinal cord
T7837 1862-1866 PR_EXT:000011459 denotes NT-3
T7838 1894-1901 UBERON:0009571 denotes midline
T7839 1909-1920 UBERON:0002240 denotes spinal cord
T7840 1941-1945 PR_EXT:000011459 denotes NT-3
T7842 2025-2033 CHEBI_SO_EXT:molecular_label_or_mark_or_tag_process denotes labeling
T7843 2046-2050 UBERON:0000044 denotes DRGs
T7844 2089-2100 UBERON:0002240 denotes spinal cord
T7845 2124-2131 GO:0040007 denotes growing
T7846 2144-2148 PR_EXT:000011459 denotes NT-3
T7847 2263-2270 CHEBI_SO_EXT:molecular_label_or_mark_or_tag_process denotes labeled
T7848 2283-2291 GO_EXT:biological_direction_or_guidance denotes directed
T7849 2311-2322 UBERON:0002240 denotes spinal cord
T7850 2375-2386 UBERON:0002315 denotes gray matter
T7851 2410-2415 GO:0030424 denotes axons
T7852 2479-2484 GO:0030424 denotes Axons
T7853 2509-2520 UBERON:0002315 denotes gray matter
T7854 2536-2547 UBERON:0002240 denotes spinal cord
T7855 2548-2552 GO:0040007 denotes grow
T7856 2565-2572 UBERON:0009571 denotes midline
T7857 2595-2604 GO_PATO_EXT:biological_localization_process_or_quality denotes localized
T7858 2605-2609 PR_EXT:000011459 denotes NT-3
T7859 2626-2630 GO:0030424 denotes axon
T7860 2631-2637 GO_EXT:biological_growth_entity_or_process denotes growth
T7861 2650-2654 PR_EXT:000011459 denotes NT-3
T7862 2678-2682 UBERON:0000044 denotes DRGs
T7863 2697-2708 UBERON:0002240 denotes spinal cord
T7864 2740-2751 UBERON:0002240 denotes spinal cord
T7865 2765-2769 PR_EXT:000011459 denotes NT-3
T7866 2806-2821 GO_EXT:0042056 denotes chemoattractant
T7867 2826-2829 UBERON:0000044 denotes DRG
T7868 2830-2835 GO:0030424 denotes axons

craft-ca-core-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T7702 28-32 PR:000011459 denotes NT-3
T7703 71-76 GO:0030424 denotes axons
T7704 120-134 GO:0019230 denotes Proprioceptive
T7705 135-140 GO:0030424 denotes axons
T7706 144-148 NCBITaxon:10088 denotes mice
T7707 159-170 UBERON:0002315 denotes gray matter
T7708 178-189 UBERON:0002240 denotes spinal cord
T7709 228-235 UBERON:0009571 denotes midline
T7710 257-270 CL:0000100 denotes motor neurons
T7711 343-346 UBERON:0000044 denotes DRG
T7712 361-365 PR:000011459 denotes NT-3
T7713 434-440 NCBITaxon:27592 denotes bovine
T7714 441-446 UBERON:0001977 denotes serum
T7715 441-454 PR:000003918 denotes serum albumin
T7716 518-521 UBERON:0000044 denotes DRG
T7717 522-527 GO:0030424 denotes axons
T7718 566-570 PR:000011459 denotes NT-3
T7719 642-657 GO:0050918 denotes chemoattraction
T7720 817-821 PR:000011459 denotes NT-3
T7721 830-833 PR:000002193 denotes Bax
T7722 839-846 UBERON:0000045 denotes ganglia
T7723 866-881 GO:0050918 denotes chemoattraction
T7724 903-907 PR:000011459 denotes NT-3
T7725 931-935 PR:000011471 denotes TrkC
T7726 944-950 PR:000001405 denotes p75NTR
T7727 996-999 UBERON:0000044 denotes DRG
T7728 1022-1028 PR:000001405 denotes p75NTR
T7729 1032-1036 NCBITaxon:10088 denotes mice
T7730 1047-1052 GO:0030424 denotes Axons
T7731 1062-1069 UBERON:0000045 denotes ganglia
T7732 1089-1104 GO:0050918 denotes chemoattraction
T7733 1117-1121 PR:000011459 denotes NT-3
T7734 1169-1173 PR:000011471 denotes TrkC
T7735 1184-1194 MOP:0000779 denotes conjugated
T7736 1198-1201 GO:0071735 denotes IgG
T7737 1220-1224 PR:000011471 denotes TrkC
T7738 1276-1280 PR:000011459 denotes NT-3
T7739 1336-1340 PR:000011471 denotes TrkC
T7740 1348-1363 GO:0050918 denotes chemoattraction
T7741 1441-1445 PR:000011459 denotes NT-3
T7742 1544-1548 UBERON:0000044 denotes DRGs
T7743 1603-1610 UBERON:0000045 denotes ganglia
T7744 1752-1757 GO:0030424 denotes axons
T7745 1823-1826 UBERON:0000044 denotes DRG
T7746 1827-1838 UBERON:0002240 denotes spinal cord
T7747 1862-1866 PR:000011459 denotes NT-3
T7748 1894-1901 UBERON:0009571 denotes midline
T7749 1909-1920 UBERON:0002240 denotes spinal cord
T7750 1941-1945 PR:000011459 denotes NT-3
T7751 2021-2024 CHEBI:52029 denotes DiI
T7752 2046-2050 UBERON:0000044 denotes DRGs
T7753 2089-2100 UBERON:0002240 denotes spinal cord
T7754 2124-2131 GO:0040007 denotes growing
T7755 2144-2148 PR:000011459 denotes NT-3
T7756 2311-2322 UBERON:0002240 denotes spinal cord
T7757 2375-2386 UBERON:0002315 denotes gray matter
T7758 2410-2415 GO:0030424 denotes axons
T7759 2479-2484 GO:0030424 denotes Axons
T7760 2509-2520 UBERON:0002315 denotes gray matter
T7761 2536-2547 UBERON:0002240 denotes spinal cord
T7762 2548-2552 GO:0040007 denotes grow
T7763 2565-2572 UBERON:0009571 denotes midline
T7764 2605-2609 PR:000011459 denotes NT-3
T7765 2626-2630 GO:0030424 denotes axon
T7766 2650-2654 PR:000011459 denotes NT-3
T7767 2678-2682 UBERON:0000044 denotes DRGs
T7768 2697-2708 UBERON:0002240 denotes spinal cord
T7769 2740-2751 UBERON:0002240 denotes spinal cord
T7770 2765-2769 PR:000011459 denotes NT-3
T7771 2826-2829 UBERON:0000044 denotes DRG
T7772 2830-2835 GO:0030424 denotes axons

craft-sa-dev

Id Subject Object Predicate Lexical cue
T7881 0-2 TO denotes To
T7882 3-7 VB denotes test
T7883 81-90 VBD denotes performed
T7884 8-11 DT denotes the
T7885 12-22 NN denotes hypothesis
T7886 23-27 IN denotes that
T7887 33-37 VBZ denotes acts
T7888 28-30 NN denotes NT
T7889 30-31 HYPH denotes -
T7890 31-32 CD denotes 3
T7891 38-40 IN denotes as
T7892 41-42 DT denotes a
T7893 43-58 NN denotes chemoattractant
T7894 59-62 IN denotes for
T7895 63-70 JJ denotes sensory
T7896 71-76 NNS denotes axons
T7897 76-78 , denotes ,
T7898 78-80 PRP denotes we
T7899 91-92 DT denotes a
T7900 93-99 NN denotes series
T7901 100-102 IN denotes of
T7902 103-105 FW denotes in
T7903 106-111 FW denotes vitro
T7904 112-118 NNS denotes assays
T7905 118-119 . denotes .
T7906 119-302 sentence denotes Proprioceptive axons in mice enter the gray matter in the spinal cord and advance ventrally parallel to the midline by E13 and reach the motor neurons by E15 (Ozaki and Snider 1994).
T7907 120-134 JJ denotes Proprioceptive
T7908 135-140 NNS denotes axons
T7909 149-154 VBP denotes enter
T7910 141-143 IN denotes in
T7911 144-148 NNS denotes mice
T7912 155-158 DT denotes the
T7913 164-170 NN denotes matter
T7914 159-163 JJ denotes gray
T7915 171-173 IN denotes in
T7916 174-177 DT denotes the
T7917 185-189 NN denotes cord
T7918 178-184 JJ denotes spinal
T7919 190-193 CC denotes and
T7920 194-201 VBP denotes advance
T7921 202-211 RB denotes ventrally
T7922 212-220 RB denotes parallel
T7923 221-223 IN denotes to
T7924 224-227 DT denotes the
T7925 228-235 NN denotes midline
T7926 236-238 IN denotes by
T7927 239-242 NN denotes E13
T7928 243-246 CC denotes and
T7929 247-252 VBP denotes reach
T7930 253-256 DT denotes the
T7931 263-270 NNS denotes neurons
T7932 257-262 NN denotes motor
T7933 271-273 IN denotes by
T7934 274-277 NN denotes E15
T7935 278-279 -LRB- denotes (
T7936 279-284 NNP denotes Ozaki
T7937 285-288 CC denotes and
T7938 289-295 NNP denotes Snider
T7939 296-300 CD denotes 1994
T7940 300-301 -RRB- denotes )
T7941 301-302 . denotes .
T7942 302-398 sentence denotes We co-cultured collagen-embedded E13 WT DRG explants with NT-3-soaked sepharose beads (n = 26).
T7943 303-305 PRP denotes We
T7944 306-317 VBD denotes co-cultured
T7945 318-326 NN denotes collagen
T7946 327-335 VBN denotes embedded
T7947 326-327 HYPH denotes -
T7948 347-355 NNS denotes explants
T7949 336-339 NN denotes E13
T7950 340-342 NN denotes WT
T7951 343-346 NN denotes DRG
T7952 356-360 IN denotes with
T7953 361-363 NN denotes NT
T7954 366-372 VBN denotes soaked
T7955 363-364 HYPH denotes -
T7956 364-365 CD denotes 3
T7957 365-366 HYPH denotes -
T7958 383-388 NNS denotes beads
T7959 373-382 NN denotes sepharose
T7960 389-390 -LRB- denotes (
T7961 394-396 CD denotes 26
T7962 390-391 NN denotes n
T7963 392-393 SYM denotes =
T7964 396-397 -RRB- denotes )
T7965 397-398 . denotes .
T7966 398-517 sentence denotes Control cultures were set up using bovine serum albumin (BSA)– or phosphate buffer saline (PBS)–soaked beads (n = 12).
T7967 399-406 NN denotes Control
T7968 407-415 NNS denotes cultures
T7969 421-424 VBN denotes set
T7970 416-420 VBD denotes were
T7971 425-427 RP denotes up
T7972 428-433 VBG denotes using
T7973 434-440 JJ denotes bovine
T7974 447-454 NN denotes albumin
T7975 441-446 NN denotes serum
T7976 495-501 VBN denotes soaked
T7977 455-456 -LRB- denotes (
T7978 456-459 NN denotes BSA
T7979 459-460 -RRB- denotes )
T7980 460-461 -LRB- denotes
T7981 462-464 CC denotes or
T7982 465-474 NN denotes phosphate
T7983 482-488 NN denotes saline
T7984 475-481 NN denotes buffer
T7985 489-490 -LRB- denotes (
T7986 490-493 NN denotes PBS
T7987 493-494 -RRB- denotes )
T7988 494-495 -RRB- denotes
T7989 502-507 NNS denotes beads
T7990 508-509 -LRB- denotes (
T7991 513-515 CD denotes 12
T7992 509-510 NN denotes n
T7993 511-512 SYM denotes =
T7994 515-516 -RRB- denotes )
T7995 516-517 . denotes .
T7996 517-765 sentence denotes DRG axons began extending towards the localized NT-3 source by the end of the first day and consistently displayed a strong chemoattraction by 3 d in vitro, whereas they did not show such preference for BSA-loaded control beads (Figure 5A and 5B).
T7997 518-521 NN denotes DRG
T7998 522-527 NNS denotes axons
T7999 528-533 VBD denotes began
T8000 534-543 VBG denotes extending
T8001 544-551 IN denotes towards
T8002 552-555 DT denotes the
T8003 571-577 NN denotes source
T8004 556-565 JJ denotes localized
T8005 566-568 NN denotes NT
T8006 568-569 HYPH denotes -
T8007 569-570 CD denotes 3
T8008 578-580 IN denotes by
T8009 581-584 DT denotes the
T8010 585-588 NN denotes end
T8011 589-591 IN denotes of
T8012 592-595 DT denotes the
T8013 602-605 NN denotes day
T8014 596-601 JJ denotes first
T8015 606-609 CC denotes and
T8016 610-622 RB denotes consistently
T8017 623-632 VBD denotes displayed
T8018 633-634 DT denotes a
T8019 642-657 NN denotes chemoattraction
T8020 635-641 JJ denotes strong
T8021 658-660 IN denotes by
T8022 661-662 CD denotes 3
T8023 663-664 NN denotes d
T8024 665-667 FW denotes in
T8025 668-673 FW denotes vitro
T8026 673-675 , denotes ,
T8027 675-682 IN denotes whereas
T8028 696-700 VB denotes show
T8029 683-687 PRP denotes they
T8030 688-691 VBD denotes did
T8031 692-695 RB denotes not
T8032 701-705 JJ denotes such
T8033 706-716 NN denotes preference
T8034 717-720 IN denotes for
T8035 721-724 NN denotes BSA
T8036 725-731 VBN denotes loaded
T8037 724-725 HYPH denotes -
T8038 740-745 NNS denotes beads
T8039 732-739 NN denotes control
T8040 746-747 -LRB- denotes (
T8041 754-756 NN denotes 5A
T8042 747-753 NN denotes Figure
T8043 757-760 CC denotes and
T8044 761-763 NN denotes 5B
T8045 763-764 -RRB- denotes )
T8046 764-765 . denotes .
T8047 765-902 sentence denotes This attraction was not due to survival support of NT-3 because Bax null ganglia displayed the same chemoattraction (Figure 5C; n = 16).
T8048 766-770 DT denotes This
T8049 771-781 NN denotes attraction
T8050 782-785 VBD denotes was
T8051 786-789 RB denotes not
T8052 790-793 IN denotes due
T8053 794-796 IN denotes to
T8054 797-805 NN denotes survival
T8055 806-813 NN denotes support
T8056 814-816 IN denotes of
T8057 817-819 NN denotes NT
T8058 819-820 HYPH denotes -
T8059 820-821 CD denotes 3
T8060 822-829 IN denotes because
T8061 847-856 VBD denotes displayed
T8062 830-833 NN denotes Bax
T8063 834-838 JJ denotes null
T8064 839-846 NNS denotes ganglia
T8065 857-860 DT denotes the
T8066 866-881 NN denotes chemoattraction
T8067 861-865 JJ denotes same
T8068 882-883 -LRB- denotes (
T8069 890-892 NN denotes 5C
T8070 883-889 NN denotes Figure
T8071 892-893 : denotes ;
T8072 894-895 NN denotes n
T8073 898-900 CD denotes 16
T8074 896-897 SYM denotes =
T8075 900-901 -RRB- denotes )
T8076 901-902 . denotes .
T8077 902-951 sentence denotes NT-3 may act through either TrkC, or the p75NTR.
T8078 903-905 NN denotes NT
T8079 912-915 VB denotes act
T8080 905-906 HYPH denotes -
T8081 906-907 CD denotes 3
T8082 908-911 MD denotes may
T8083 916-923 IN denotes through
T8084 924-930 CC denotes either
T8085 931-935 NN denotes TrkC
T8086 935-937 , denotes ,
T8087 937-939 CC denotes or
T8088 940-943 DT denotes the
T8089 944-950 NN denotes p75NTR
T8090 950-951 . denotes .
T8091 951-1046 sentence denotes We repeated the co-culture experiments with DRG explants derived from p75NTR KO mice (n = 18).
T8092 952-954 PRP denotes We
T8093 955-963 VBD denotes repeated
T8094 964-967 DT denotes the
T8095 979-990 NNS denotes experiments
T8096 968-978 NN denotes co-culture
T8097 991-995 IN denotes with
T8098 996-999 NN denotes DRG
T8099 1000-1008 NNS denotes explants
T8100 1009-1016 VBN denotes derived
T8101 1017-1021 IN denotes from
T8102 1022-1028 NN denotes p75NTR
T8103 1029-1031 NN denotes KO
T8104 1032-1036 NNS denotes mice
T8105 1037-1038 -LRB- denotes (
T8106 1042-1044 CD denotes 18
T8107 1038-1039 NN denotes n
T8108 1040-1041 SYM denotes =
T8109 1044-1045 -RRB- denotes )
T8110 1045-1046 . denotes .
T8111 1046-1140 sentence denotes Axons of these ganglia also showed strong chemoattraction towards the NT-3 beads (Figure 5D).
T8112 1047-1052 NNS denotes Axons
T8113 1075-1081 VBD denotes showed
T8114 1053-1055 IN denotes of
T8115 1056-1061 DT denotes these
T8116 1062-1069 NNS denotes ganglia
T8117 1070-1074 RB denotes also
T8118 1082-1088 JJ denotes strong
T8119 1089-1104 NN denotes chemoattraction
T8120 1105-1112 IN denotes towards
T8121 1113-1116 DT denotes the
T8122 1122-1127 NNS denotes beads
T8123 1117-1119 NN denotes NT
T8124 1119-1120 HYPH denotes -
T8125 1120-1121 CD denotes 3
T8126 1128-1129 -LRB- denotes (
T8127 1136-1138 NN denotes 5D
T8128 1129-1135 NN denotes Figure
T8129 1138-1139 -RRB- denotes )
T8130 1139-1140 . denotes .
T8131 1140-1316 sentence denotes Finally, we used diffusible TrkC receptors conjugated to IgG constant regions (TrkC-Fc) added to the medium (n = 6) to deplete soluble NT-3 from the collagen gels (Figure 5E).
T8132 1141-1148 RB denotes Finally
T8133 1153-1157 VBD denotes used
T8134 1148-1150 , denotes ,
T8135 1150-1152 PRP denotes we
T8136 1158-1168 JJ denotes diffusible
T8137 1174-1183 NNS denotes receptors
T8138 1169-1173 NN denotes TrkC
T8139 1184-1194 VBN denotes conjugated
T8140 1195-1197 IN denotes to
T8141 1198-1201 NN denotes IgG
T8142 1211-1218 NNS denotes regions
T8143 1202-1210 NN denotes constant
T8144 1219-1220 -LRB- denotes (
T8145 1225-1227 NN denotes Fc
T8146 1220-1224 NN denotes TrkC
T8147 1224-1225 HYPH denotes -
T8148 1227-1228 -RRB- denotes )
T8149 1229-1234 VBN denotes added
T8150 1235-1237 IN denotes to
T8151 1238-1241 DT denotes the
T8152 1242-1248 NN denotes medium
T8153 1249-1250 -LRB- denotes (
T8154 1254-1255 CD denotes 6
T8155 1250-1251 NN denotes n
T8156 1252-1253 SYM denotes =
T8157 1255-1256 -RRB- denotes )
T8158 1257-1259 TO denotes to
T8159 1260-1267 VB denotes deplete
T8160 1268-1275 JJ denotes soluble
T8161 1276-1278 NN denotes NT
T8162 1278-1279 HYPH denotes -
T8163 1279-1280 CD denotes 3
T8164 1281-1285 IN denotes from
T8165 1286-1289 DT denotes the
T8166 1299-1303 NNS denotes gels
T8167 1290-1298 NN denotes collagen
T8168 1304-1305 -LRB- denotes (
T8169 1312-1314 NN denotes 5E
T8170 1305-1311 NN denotes Figure
T8171 1314-1315 -RRB- denotes )
T8172 1315-1316 . denotes .
T8173 1316-1446 sentence denotes In the presence of TrkC-Fc the chemoattraction was completely blocked, demonstrating that the effect we see is specific for NT-3.
T8174 1317-1319 IN denotes In
T8175 1379-1386 VBN denotes blocked
T8176 1320-1323 DT denotes the
T8177 1324-1332 NN denotes presence
T8178 1333-1335 IN denotes of
T8179 1336-1340 NN denotes TrkC
T8180 1341-1343 NN denotes Fc
T8181 1340-1341 HYPH denotes -
T8182 1344-1347 DT denotes the
T8183 1348-1363 NN denotes chemoattraction
T8184 1364-1367 VBD denotes was
T8185 1368-1378 RB denotes completely
T8186 1386-1388 , denotes ,
T8187 1388-1401 VBG denotes demonstrating
T8188 1402-1406 IN denotes that
T8189 1425-1427 VBZ denotes is
T8190 1407-1410 DT denotes the
T8191 1411-1417 NN denotes effect
T8192 1418-1420 PRP denotes we
T8193 1421-1424 VBP denotes see
T8194 1428-1436 JJ denotes specific
T8195 1437-1440 IN denotes for
T8196 1441-1443 NN denotes NT
T8197 1443-1444 HYPH denotes -
T8198 1444-1445 CD denotes 3
T8199 1445-1446 . denotes .
T8200 1446-1636 sentence denotes In order to investigate the active range of our beads, we have repeated the cultures with WT E13 DRGs by placing the beads at increasing distances from the ganglia (n = 4 each) (Figure 5F).
T8201 1447-1449 IN denotes In
T8202 1510-1518 VBN denotes repeated
T8203 1450-1455 NN denotes order
T8204 1456-1458 TO denotes to
T8205 1459-1470 VB denotes investigate
T8206 1471-1474 DT denotes the
T8207 1482-1487 NN denotes range
T8208 1475-1481 JJ denotes active
T8209 1488-1490 IN denotes of
T8210 1491-1494 PRP$ denotes our
T8211 1495-1500 NNS denotes beads
T8212 1500-1502 , denotes ,
T8213 1502-1504 PRP denotes we
T8214 1505-1509 VBP denotes have
T8215 1519-1522 DT denotes the
T8216 1523-1531 NNS denotes cultures
T8217 1532-1536 IN denotes with
T8218 1537-1539 NN denotes WT
T8219 1544-1548 NNS denotes DRGs
T8220 1540-1543 NN denotes E13
T8221 1549-1551 IN denotes by
T8222 1552-1559 VBG denotes placing
T8223 1560-1563 DT denotes the
T8224 1564-1569 NNS denotes beads
T8225 1570-1572 IN denotes at
T8226 1573-1583 VBG denotes increasing
T8227 1584-1593 NNS denotes distances
T8228 1594-1598 IN denotes from
T8229 1599-1602 DT denotes the
T8230 1603-1610 NNS denotes ganglia
T8231 1611-1612 -LRB- denotes (
T8232 1616-1617 CD denotes 4
T8233 1612-1613 NN denotes n
T8234 1614-1615 SYM denotes =
T8235 1618-1622 DT denotes each
T8236 1622-1623 -RRB- denotes )
T8237 1624-1625 -LRB- denotes (
T8238 1632-1634 NN denotes 5F
T8239 1625-1631 NN denotes Figure
T8240 1634-1635 -RRB- denotes )
T8241 1635-1636 . denotes .
T8242 1636-1802 sentence denotes There was still preferred growth towards the bead at 1,200μm, the longest distance studied, although the number of axons and the extent of growth were not as robust.
T8243 1637-1642 EX denotes There
T8244 1643-1646 VBD denotes was
T8245 1647-1652 RB denotes still
T8246 1653-1662 JJ denotes preferred
T8247 1663-1669 NN denotes growth
T8248 1670-1677 IN denotes towards
T8249 1678-1681 DT denotes the
T8250 1682-1686 NN denotes bead
T8251 1687-1689 IN denotes at
T8252 1690-1695 CD denotes 1,200
T8253 1695-1697 NN denotes μm
T8254 1697-1699 , denotes ,
T8255 1699-1702 DT denotes the
T8256 1711-1719 NN denotes distance
T8257 1703-1710 JJS denotes longest
T8258 1720-1727 VBN denotes studied
T8259 1727-1729 , denotes ,
T8260 1729-1737 IN denotes although
T8261 1783-1787 VBD denotes were
T8262 1738-1741 DT denotes the
T8263 1742-1748 NN denotes number
T8264 1749-1751 IN denotes of
T8265 1752-1757 NNS denotes axons
T8266 1758-1761 CC denotes and
T8267 1762-1765 DT denotes the
T8268 1766-1772 NN denotes extent
T8269 1773-1775 IN denotes of
T8270 1776-1782 NN denotes growth
T8271 1788-1791 RB denotes not
T8272 1792-1794 RB denotes as
T8273 1795-1801 JJ denotes robust
T8274 1801-1802 . denotes .
T8275 1802-1962 sentence denotes Next, we set up E13 DRG spinal cord explant cultures using NT-3-loaded beads placed at the midline at mid-spinal cord level as an ectopic NT-3 source (n = 15).
T8276 1803-1807 RB denotes Next
T8277 1812-1815 VBD denotes set
T8278 1807-1809 , denotes ,
T8279 1809-1811 PRP denotes we
T8280 1816-1818 RP denotes up
T8281 1819-1822 NN denotes E13
T8282 1847-1855 NNS denotes cultures
T8283 1823-1826 NN denotes DRG
T8284 1827-1833 JJ denotes spinal
T8285 1834-1838 NN denotes cord
T8286 1839-1846 NN denotes explant
T8287 1856-1861 VBG denotes using
T8288 1862-1864 NN denotes NT
T8289 1867-1873 VBN denotes loaded
T8290 1864-1865 HYPH denotes -
T8291 1865-1866 CD denotes 3
T8292 1866-1867 HYPH denotes -
T8293 1874-1879 NNS denotes beads
T8294 1880-1886 VBN denotes placed
T8295 1887-1889 IN denotes at
T8296 1890-1893 DT denotes the
T8297 1894-1901 NN denotes midline
T8298 1902-1904 IN denotes at
T8299 1905-1915 JJ denotes mid-spinal
T8300 1921-1926 NN denotes level
T8301 1916-1920 NN denotes cord
T8302 1927-1929 IN denotes as
T8303 1930-1932 DT denotes an
T8304 1946-1952 NN denotes source
T8305 1933-1940 JJ denotes ectopic
T8306 1941-1943 NN denotes NT
T8307 1943-1944 HYPH denotes -
T8308 1944-1945 CD denotes 3
T8309 1953-1954 -LRB- denotes (
T8310 1958-1960 CD denotes 15
T8311 1954-1955 NN denotes n
T8312 1956-1957 SYM denotes =
T8313 1960-1961 -RRB- denotes )
T8314 1961-1962 . denotes .
T8315 1962-2020 sentence denotes Control cultures were set using PBS-loaded beads (n = 6).
T8316 1963-1970 NN denotes Control
T8317 1971-1979 NNS denotes cultures
T8318 1985-1988 VBN denotes set
T8319 1980-1984 VBD denotes were
T8320 1989-1994 VBG denotes using
T8321 1995-1998 NN denotes PBS
T8322 1999-2005 VBN denotes loaded
T8323 1998-1999 HYPH denotes -
T8324 2006-2011 NNS denotes beads
T8325 2012-2013 -LRB- denotes (
T8326 2017-2018 CD denotes 6
T8327 2013-2014 NN denotes n
T8328 2015-2016 SYM denotes =
T8329 2018-2019 -RRB- denotes )
T8330 2019-2020 . denotes .
T8331 2020-2237 sentence denotes DiI labeling through the DRGs revealed numerous fibers entering the spinal cord at ectopic regions and growing towards the NT-3 beads (Figure 6A), surrounding the beads and forming bundles around them (Figure 6C–6E).
T8332 2021-2024 NN denotes DiI
T8333 2025-2033 NN denotes labeling
T8334 2051-2059 VBD denotes revealed
T8335 2034-2041 IN denotes through
T8336 2042-2045 DT denotes the
T8337 2046-2050 NNS denotes DRGs
T8338 2060-2068 JJ denotes numerous
T8339 2069-2075 NNS denotes fibers
T8340 2076-2084 VBG denotes entering
T8341 2085-2088 DT denotes the
T8342 2096-2100 NN denotes cord
T8343 2089-2095 JJ denotes spinal
T8344 2101-2103 IN denotes at
T8345 2104-2111 JJ denotes ectopic
T8346 2112-2119 NNS denotes regions
T8347 2120-2123 CC denotes and
T8348 2124-2131 VBG denotes growing
T8349 2132-2139 IN denotes towards
T8350 2140-2143 DT denotes the
T8351 2149-2154 NNS denotes beads
T8352 2144-2146 NN denotes NT
T8353 2146-2147 HYPH denotes -
T8354 2147-2148 CD denotes 3
T8355 2155-2156 -LRB- denotes (
T8356 2163-2165 NN denotes 6A
T8357 2156-2162 NN denotes Figure
T8358 2165-2166 -RRB- denotes )
T8359 2166-2168 , denotes ,
T8360 2168-2179 VBG denotes surrounding
T8361 2180-2183 DT denotes the
T8362 2184-2189 NNS denotes beads
T8363 2190-2193 CC denotes and
T8364 2194-2201 VBG denotes forming
T8365 2202-2209 NNS denotes bundles
T8366 2210-2216 IN denotes around
T8367 2217-2221 PRP denotes them
T8368 2222-2223 -LRB- denotes (
T8369 2230-2232 NN denotes 6C
T8370 2223-2229 NN denotes Figure
T8371 2232-2233 SYM denotes
T8372 2233-2235 NN denotes 6E
T8373 2235-2236 -RRB- denotes )
T8374 2236-2237 . denotes .
T8375 2237-2406 sentence denotes In control cultures, all labeled fibers were directed towards the dorsal spinal cord and terminated there, where they normally enter the gray matter at E13 (Figure 6B).
T8376 2238-2240 IN denotes In
T8377 2283-2291 VBN denotes directed
T8378 2241-2248 NN denotes control
T8379 2249-2257 NNS denotes cultures
T8380 2257-2259 , denotes ,
T8381 2259-2262 DT denotes all
T8382 2271-2277 NNS denotes fibers
T8383 2263-2270 VBN denotes labeled
T8384 2278-2282 VBD denotes were
T8385 2292-2299 IN denotes towards
T8386 2300-2303 DT denotes the
T8387 2318-2322 NN denotes cord
T8388 2304-2310 JJ denotes dorsal
T8389 2311-2317 JJ denotes spinal
T8390 2323-2326 CC denotes and
T8391 2327-2337 VBN denotes terminated
T8392 2338-2343 RB denotes there
T8393 2343-2345 , denotes ,
T8394 2345-2350 WRB denotes where
T8395 2365-2370 VBP denotes enter
T8396 2351-2355 PRP denotes they
T8397 2356-2364 RB denotes normally
T8398 2371-2374 DT denotes the
T8399 2380-2386 NN denotes matter
T8400 2375-2379 JJ denotes gray
T8401 2387-2389 IN denotes at
T8402 2390-2393 NN denotes E13
T8403 2394-2395 -LRB- denotes (
T8404 2402-2404 NN denotes 6B
T8405 2395-2401 NN denotes Figure
T8406 2404-2405 -RRB- denotes )
T8407 2405-2406 . denotes .
T8408 2406-2478 sentence denotes No axons were observed around the PBS-loaded control beads (Figure 6F).
T8409 2407-2409 DT denotes No
T8410 2410-2415 NNS denotes axons
T8411 2421-2429 VBN denotes observed
T8412 2416-2420 VBD denotes were
T8413 2430-2436 IN denotes around
T8414 2437-2440 DT denotes the
T8415 2460-2465 NNS denotes beads
T8416 2441-2444 NN denotes PBS
T8417 2445-2451 VBN denotes loaded
T8418 2444-2445 HYPH denotes -
T8419 2452-2459 NN denotes control
T8420 2466-2467 -LRB- denotes (
T8421 2474-2476 NN denotes 6F
T8422 2467-2473 NN denotes Figure
T8423 2476-2477 -RRB- denotes )
T8424 2477-2478 . denotes .
T8425 2478-2764 sentence denotes Axons that normally enter the gray matter through dorsal spinal cord grow towards the midline when presented with a localized NT-3 source, and new axon growth towards the NT-3 bead is initiated from DRGs, entering the spinal cord at ectopic loci at lateral mid-spinal cord (Figure 6G).
T8426 2479-2484 NNS denotes Axons
T8427 2548-2552 VBP denotes grow
T8428 2485-2489 WDT denotes that
T8429 2499-2504 VBP denotes enter
T8430 2490-2498 RB denotes normally
T8431 2505-2508 DT denotes the
T8432 2514-2520 NN denotes matter
T8433 2509-2513 JJ denotes gray
T8434 2521-2528 IN denotes through
T8435 2529-2535 JJ denotes dorsal
T8436 2543-2547 NN denotes cord
T8437 2536-2542 JJ denotes spinal
T8438 2553-2560 IN denotes towards
T8439 2561-2564 DT denotes the
T8440 2565-2572 NN denotes midline
T8441 2573-2577 WRB denotes when
T8442 2578-2587 VBN denotes presented
T8443 2588-2592 IN denotes with
T8444 2593-2594 DT denotes a
T8445 2610-2616 NN denotes source
T8446 2595-2604 JJ denotes localized
T8447 2605-2607 NN denotes NT
T8448 2607-2608 HYPH denotes -
T8449 2608-2609 CD denotes 3
T8450 2616-2618 , denotes ,
T8451 2618-2621 CC denotes and
T8452 2622-2625 JJ denotes new
T8453 2631-2637 NN denotes growth
T8454 2626-2630 NN denotes axon
T8455 2663-2672 VBN denotes initiated
T8456 2638-2645 IN denotes towards
T8457 2646-2649 DT denotes the
T8458 2655-2659 NN denotes bead
T8459 2650-2652 NN denotes NT
T8460 2652-2653 HYPH denotes -
T8461 2653-2654 CD denotes 3
T8462 2660-2662 VBZ denotes is
T8463 2673-2677 IN denotes from
T8464 2678-2682 NNS denotes DRGs
T8465 2682-2684 , denotes ,
T8466 2684-2692 VBG denotes entering
T8467 2693-2696 DT denotes the
T8468 2704-2708 NN denotes cord
T8469 2697-2703 JJ denotes spinal
T8470 2709-2711 IN denotes at
T8471 2712-2719 JJ denotes ectopic
T8472 2720-2724 NNS denotes loci
T8473 2725-2727 IN denotes at
T8474 2728-2735 JJ denotes lateral
T8475 2747-2751 NN denotes cord
T8476 2736-2746 JJ denotes mid-spinal
T8477 2752-2753 -LRB- denotes (
T8478 2760-2762 NN denotes 6G
T8479 2753-2759 NN denotes Figure
T8480 2762-2763 -RRB- denotes )
T8481 2763-2764 . denotes .
T8482 2764-2836 sentence denotes NT-3 is therefore capable of acting as a chemoattractant for DRG axons.
T8483 2765-2767 NN denotes NT
T8484 2770-2772 VBZ denotes is
T8485 2767-2768 HYPH denotes -
T8486 2768-2769 CD denotes 3
T8487 2773-2782 RB denotes therefore
T8488 2783-2790 JJ denotes capable
T8489 2791-2793 IN denotes of
T8490 2794-2800 VBG denotes acting
T8491 2801-2803 IN denotes as
T8492 2804-2805 DT denotes a
T8493 2806-2821 NN denotes chemoattractant
T8494 2822-2825 IN denotes for
T8495 2826-2829 NN denotes DRG
T8496 2830-2835 NNS denotes axons
T8497 2835-2836 . denotes .
R1955 T7881 T7882 aux To,test
R1956 T7882 T7883 advcl test,performed
R1957 T7884 T7885 det the,hypothesis
R1958 T7885 T7882 dobj hypothesis,test
R1959 T7886 T7887 mark that,acts
R1960 T7887 T7885 acl acts,hypothesis
R1961 T7888 T7887 nsubj NT,acts
R1962 T7889 T7888 punct -,NT
R1963 T7890 T7888 nummod 3,NT
R1964 T7891 T7887 prep as,acts
R1965 T7892 T7893 det a,chemoattractant
R1966 T7893 T7891 pobj chemoattractant,as
R1967 T7894 T7893 prep for,chemoattractant
R1968 T7895 T7896 amod sensory,axons
R1969 T7896 T7894 pobj axons,for
R1970 T7897 T7883 punct ", ",performed
R1971 T7898 T7883 nsubj we,performed
R1972 T7899 T7900 det a,series
R1973 T7900 T7883 dobj series,performed
R1974 T7901 T7900 prep of,series
R1975 T7902 T7903 advmod in,vitro
R1976 T7903 T7904 amod vitro,assays
R1977 T7904 T7901 pobj assays,of
R1978 T7905 T7883 punct .,performed
R1979 T7907 T7908 amod Proprioceptive,axons
R1980 T7908 T7909 nsubj axons,enter
R1981 T7910 T7908 prep in,axons
R1982 T7911 T7910 pobj mice,in
R1983 T7912 T7913 det the,matter
R1984 T7913 T7909 dobj matter,enter
R1985 T7914 T7913 amod gray,matter
R1986 T7915 T7913 prep in,matter
R1987 T7916 T7917 det the,cord
R1988 T7917 T7915 pobj cord,in
R1989 T7918 T7917 amod spinal,cord
R1990 T7919 T7909 cc and,enter
R1991 T7920 T7909 conj advance,enter
R1992 T7921 T7920 advmod ventrally,advance
R1993 T7922 T7920 advcl parallel,advance
R1994 T7923 T7922 prep to,parallel
R1995 T7924 T7925 det the,midline
R1996 T7925 T7923 pobj midline,to
R1997 T7926 T7920 prep by,advance
R1998 T7927 T7926 pobj E13,by
R1999 T7928 T7920 cc and,advance
R2000 T7929 T7920 conj reach,advance
R2001 T7930 T7931 det the,neurons
R2002 T7931 T7929 dobj neurons,reach
R2003 T7932 T7931 compound motor,neurons
R2004 T7933 T7929 prep by,reach
R2005 T7934 T7933 pobj E15,by
R2006 T7935 T7936 punct (,Ozaki
R2007 T7936 T7929 meta Ozaki,reach
R2008 T7937 T7936 cc and,Ozaki
R2009 T7938 T7936 conj Snider,Ozaki
R2010 T7939 T7938 nummod 1994,Snider
R2011 T7940 T7938 punct ),Snider
R2012 T7941 T7909 punct .,enter
R2013 T7943 T7944 nsubj We,co-cultured
R2014 T7945 T7946 npadvmod collagen,embedded
R2015 T7946 T7948 amod embedded,explants
R2016 T7947 T7946 punct -,embedded
R2017 T7948 T7944 dobj explants,co-cultured
R2018 T7949 T7948 compound E13,explants
R2019 T7950 T7948 compound WT,explants
R2020 T7951 T7948 compound DRG,explants
R2021 T7952 T7944 prep with,co-cultured
R2022 T7953 T7954 npadvmod NT,soaked
R2023 T7954 T7958 amod soaked,beads
R2024 T7955 T7953 punct -,NT
R2025 T7956 T7953 nummod 3,NT
R2026 T7957 T7954 punct -,soaked
R2027 T7958 T7952 pobj beads,with
R2028 T7959 T7958 compound sepharose,beads
R2029 T7960 T7961 punct (,26
R2030 T7961 T7944 parataxis 26,co-cultured
R2031 T7962 T7961 nsubj n,26
R2032 T7963 T7961 punct =,26
R2033 T7964 T7961 punct ),26
R2034 T7965 T7944 punct .,co-cultured
R2035 T7967 T7968 compound Control,cultures
R2036 T7968 T7969 nsubjpass cultures,set
R2037 T7970 T7969 auxpass were,set
R2038 T7971 T7969 prt up,set
R2039 T7972 T7969 advcl using,set
R2040 T7973 T7974 amod bovine,albumin
R2041 T7974 T7976 npadvmod albumin,soaked
R2042 T7975 T7974 compound serum,albumin
R2043 T7976 T7989 amod soaked,beads
R2044 T7977 T7974 punct (,albumin
R2045 T7978 T7974 appos BSA,albumin
R2046 T7979 T7974 punct ),albumin
R2047 T7980 T7974 punct –,albumin
R2048 T7981 T7974 cc or,albumin
R2049 T7982 T7983 compound phosphate,saline
R2050 T7983 T7974 conj saline,albumin
R2051 T7984 T7983 compound buffer,saline
R2052 T7985 T7983 punct (,saline
R2053 T7986 T7983 appos PBS,saline
R2054 T7987 T7976 punct ),soaked
R2055 T7988 T7976 punct –,soaked
R2056 T7989 T7972 dobj beads,using
R2057 T7990 T7991 punct (,12
R2058 T7991 T7972 parataxis 12,using
R2059 T7992 T7991 nsubj n,12
R2060 T7993 T7991 punct =,12
R2061 T7994 T7991 punct ),12
R2062 T7995 T7969 punct .,set
R2063 T7997 T7998 compound DRG,axons
R2064 T7998 T7999 nsubj axons,began
R2065 T8000 T7999 xcomp extending,began
R2066 T8001 T8000 prep towards,extending
R2067 T8002 T8003 det the,source
R2068 T8003 T8001 pobj source,towards
R2069 T8004 T8003 amod localized,source
R2070 T8005 T8003 nmod NT,source
R2071 T8006 T8005 punct -,NT
R2072 T8007 T8005 nummod 3,NT
R2073 T8008 T8000 prep by,extending
R2074 T8009 T8010 det the,end
R2075 T8010 T8008 pobj end,by
R2076 T8011 T8010 prep of,end
R2077 T8012 T8013 det the,day
R2078 T8013 T8011 pobj day,of
R2079 T8014 T8013 amod first,day
R2080 T8015 T7999 cc and,began
R2081 T8016 T8017 advmod consistently,displayed
R2082 T8017 T7999 conj displayed,began
R2083 T8018 T8019 det a,chemoattraction
R2084 T8019 T8017 dobj chemoattraction,displayed
R2085 T8020 T8019 amod strong,chemoattraction
R2086 T8021 T8017 prep by,displayed
R2087 T8022 T8023 nummod 3,d
R2088 T8023 T8021 pobj d,by
R2089 T8024 T8025 advmod in,vitro
R2090 T8025 T8023 advmod vitro,d
R2091 T8026 T8017 punct ", ",displayed
R2092 T8027 T8028 mark whereas,show
R2093 T8028 T8017 advcl show,displayed
R2094 T8029 T8028 nsubj they,show
R2095 T8030 T8028 aux did,show
R2096 T8031 T8028 neg not,show
R2097 T8032 T8033 amod such,preference
R2098 T8033 T8028 dobj preference,show
R2099 T8034 T8033 prep for,preference
R2100 T8035 T8036 npadvmod BSA,loaded
R2101 T8036 T8038 amod loaded,beads
R2102 T8037 T8036 punct -,loaded
R2103 T8038 T8034 pobj beads,for
R2104 T8039 T8038 compound control,beads
R2105 T8040 T8041 punct (,5A
R2106 T8041 T8017 parataxis 5A,displayed
R2107 T8042 T8041 compound Figure,5A
R2108 T8043 T8041 cc and,5A
R2109 T8044 T8041 conj 5B,5A
R2110 T8045 T8041 punct ),5A
R2111 T8046 T7999 punct .,began
R2112 T8048 T8049 det This,attraction
R2113 T8049 T8050 nsubj attraction,was
R2114 T8051 T8050 neg not,was
R2115 T8052 T8050 prep due,was
R2116 T8053 T8052 pcomp to,due
R2117 T8054 T8055 compound survival,support
R2118 T8055 T8052 pobj support,due
R2119 T8056 T8055 prep of,support
R2120 T8057 T8056 pobj NT,of
R2121 T8058 T8057 punct -,NT
R2122 T8059 T8057 nummod 3,NT
R2123 T8060 T8061 mark because,displayed
R2124 T8061 T8050 advcl displayed,was
R2125 T8062 T8063 npadvmod Bax,null
R2126 T8063 T8064 amod null,ganglia
R2127 T8064 T8061 nsubj ganglia,displayed
R2128 T8065 T8066 det the,chemoattraction
R2129 T8066 T8061 dobj chemoattraction,displayed
R2130 T8067 T8066 amod same,chemoattraction
R2131 T8068 T8069 punct (,5C
R2132 T8069 T8050 parataxis 5C,was
R2133 T8070 T8069 compound Figure,5C
R2134 T8071 T8069 punct ;,5C
R2135 T8072 T8073 nsubj n,16
R2136 T8073 T8069 ccomp 16,5C
R2137 T8074 T8073 punct =,16
R2138 T8075 T8069 punct ),5C
R2139 T8076 T8050 punct .,was
R2140 T8078 T8079 nsubj NT,act
R2141 T8080 T8078 punct -,NT
R2142 T8081 T8078 nummod 3,NT
R2143 T8082 T8079 aux may,act
R2144 T8083 T8079 prep through,act
R2145 T8084 T8085 preconj either,TrkC
R2146 T8085 T8083 pobj TrkC,through
R2147 T8086 T8085 punct ", ",TrkC
R2148 T8087 T8085 cc or,TrkC
R2149 T8088 T8089 det the,p75NTR
R2150 T8089 T8085 conj p75NTR,TrkC
R2151 T8090 T8079 punct .,act
R2152 T8092 T8093 nsubj We,repeated
R2153 T8094 T8095 det the,experiments
R2154 T8095 T8093 dobj experiments,repeated
R2155 T8096 T8095 compound co-culture,experiments
R2156 T8097 T8093 prep with,repeated
R2157 T8098 T8099 compound DRG,explants
R2158 T8099 T8097 pobj explants,with
R2159 T8100 T8099 acl derived,explants
R2160 T8101 T8100 prep from,derived
R2161 T8102 T8103 compound p75NTR,KO
R2162 T8103 T8104 compound KO,mice
R2163 T8104 T8101 pobj mice,from
R2164 T8105 T8106 punct (,18
R2165 T8106 T8093 parataxis 18,repeated
R2166 T8107 T8106 nsubj n,18
R2167 T8108 T8106 punct =,18
R2168 T8109 T8106 punct ),18
R2169 T8110 T8093 punct .,repeated
R2170 T8112 T8113 nsubj Axons,showed
R2171 T8114 T8112 prep of,Axons
R2172 T8115 T8116 det these,ganglia
R2173 T8116 T8114 pobj ganglia,of
R2174 T8117 T8113 advmod also,showed
R2175 T8118 T8119 amod strong,chemoattraction
R2176 T8119 T8113 dobj chemoattraction,showed
R2177 T8120 T8119 prep towards,chemoattraction
R2178 T8121 T8122 det the,beads
R2179 T8122 T8120 pobj beads,towards
R2180 T8123 T8122 nmod NT,beads
R2181 T8124 T8123 punct -,NT
R2182 T8125 T8123 nummod 3,NT
R2183 T8126 T8127 punct (,5D
R2184 T8127 T8113 parataxis 5D,showed
R2185 T8128 T8127 compound Figure,5D
R2186 T8129 T8127 punct ),5D
R2187 T8130 T8113 punct .,showed
R2188 T8132 T8133 advmod Finally,used
R2189 T8134 T8133 punct ", ",used
R2190 T8135 T8133 nsubj we,used
R2191 T8136 T8137 amod diffusible,receptors
R2192 T8137 T8133 dobj receptors,used
R2193 T8138 T8137 compound TrkC,receptors
R2194 T8139 T8137 acl conjugated,receptors
R2195 T8140 T8139 prep to,conjugated
R2196 T8141 T8142 compound IgG,regions
R2197 T8142 T8140 pobj regions,to
R2198 T8143 T8142 compound constant,regions
R2199 T8144 T8145 punct (,Fc
R2200 T8145 T8142 parataxis Fc,regions
R2201 T8146 T8145 compound TrkC,Fc
R2202 T8147 T8145 punct -,Fc
R2203 T8148 T8145 punct ),Fc
R2204 T8149 T8142 acl added,regions
R2205 T8150 T8149 prep to,added
R2206 T8151 T8152 det the,medium
R2207 T8152 T8150 pobj medium,to
R2208 T8153 T8154 punct (,6
R2209 T8154 T8149 parataxis 6,added
R2210 T8155 T8154 nsubj n,6
R2211 T8156 T8154 punct =,6
R2212 T8157 T8154 punct ),6
R2213 T8158 T8159 aux to,deplete
R2214 T8159 T8133 advcl deplete,used
R2215 T8160 T8161 amod soluble,NT
R2216 T8161 T8159 dobj NT,deplete
R2217 T8162 T8161 punct -,NT
R2218 T8163 T8161 nummod 3,NT
R2219 T8164 T8159 prep from,deplete
R2220 T8165 T8166 det the,gels
R2221 T8166 T8164 pobj gels,from
R2222 T8167 T8166 compound collagen,gels
R2223 T8168 T8169 punct (,5E
R2224 T8169 T8133 parataxis 5E,used
R2225 T8170 T8169 compound Figure,5E
R2226 T8171 T8169 punct ),5E
R2227 T8172 T8133 punct .,used
R2228 T8174 T8175 prep In,blocked
R2229 T8176 T8177 det the,presence
R2230 T8177 T8174 pobj presence,In
R2231 T8178 T8177 prep of,presence
R2232 T8179 T8180 compound TrkC,Fc
R2233 T8180 T8178 pobj Fc,of
R2234 T8181 T8180 punct -,Fc
R2235 T8182 T8183 det the,chemoattraction
R2236 T8183 T8175 nsubjpass chemoattraction,blocked
R2237 T8184 T8175 auxpass was,blocked
R2238 T8185 T8175 advmod completely,blocked
R2239 T8186 T8175 punct ", ",blocked
R2240 T8187 T8175 advcl demonstrating,blocked
R2241 T8188 T8189 mark that,is
R2242 T8189 T8187 ccomp is,demonstrating
R2243 T8190 T8191 det the,effect
R2244 T8191 T8189 nsubj effect,is
R2245 T8192 T8193 nsubj we,see
R2246 T8193 T8191 advcl see,effect
R2247 T8194 T8189 acomp specific,is
R2248 T8195 T8194 prep for,specific
R2249 T8196 T8195 pobj NT,for
R2250 T8197 T8196 punct -,NT
R2251 T8198 T8196 nummod 3,NT
R2252 T8199 T8175 punct .,blocked
R2253 T8201 T8202 prep In,repeated
R2254 T8203 T8201 pobj order,In
R2255 T8204 T8205 aux to,investigate
R2256 T8205 T8203 acl investigate,order
R2257 T8206 T8207 det the,range
R2258 T8207 T8205 dobj range,investigate
R2259 T8208 T8207 amod active,range
R2260 T8209 T8207 prep of,range
R2261 T8210 T8211 poss our,beads
R2262 T8211 T8209 pobj beads,of
R2263 T8212 T8202 punct ", ",repeated
R2264 T8213 T8202 nsubj we,repeated
R2265 T8214 T8202 aux have,repeated
R2266 T8215 T8216 det the,cultures
R2267 T8216 T8202 dobj cultures,repeated
R2268 T8217 T8202 prep with,repeated
R2269 T8218 T8219 compound WT,DRGs
R2270 T8219 T8217 pobj DRGs,with
R2271 T8220 T8219 compound E13,DRGs
R2272 T8221 T8202 prep by,repeated
R2273 T8222 T8221 pcomp placing,by
R2274 T8223 T8224 det the,beads
R2275 T8224 T8222 dobj beads,placing
R2276 T8225 T8222 prep at,placing
R2277 T8226 T8227 amod increasing,distances
R2278 T8227 T8225 pobj distances,at
R2279 T8228 T8227 prep from,distances
R2280 T8229 T8230 det the,ganglia
R2281 T8230 T8228 pobj ganglia,from
R2282 T8231 T8232 punct (,4
R2283 T8232 T8222 parataxis 4,placing
R2284 T8233 T8232 nsubj n,4
R2285 T8234 T8232 punct =,4
R2286 T8235 T8232 appos each,4
R2287 T8236 T8232 punct ),4
R2288 T8237 T8238 punct (,5F
R2289 T8238 T8222 parataxis 5F,placing
R2290 T8239 T8238 compound Figure,5F
R2291 T8240 T8238 punct ),5F
R2292 T8241 T8202 punct .,repeated
R2293 T8243 T8244 expl There,was
R2294 T8245 T8244 advmod still,was
R2295 T8246 T8247 amod preferred,growth
R2296 T8247 T8244 attr growth,was
R2297 T8248 T8247 prep towards,growth
R2298 T8249 T8250 det the,bead
R2299 T8250 T8248 pobj bead,towards
R2300 T8251 T8250 prep at,bead
R2301 T8252 T8253 nummod "1,200",μm
R2302 T8253 T8251 pobj μm,at
R2303 T8254 T8253 punct ", ",μm
R2304 T8255 T8256 det the,distance
R2305 T8256 T8253 appos distance,μm
R2306 T8257 T8256 amod longest,distance
R2307 T8258 T8256 acl studied,distance
R2308 T8259 T8244 punct ", ",was
R2309 T8260 T8261 mark although,were
R2310 T8261 T8244 advcl were,was
R2311 T8262 T8263 det the,number
R2312 T8263 T8261 nsubj number,were
R2313 T8264 T8263 prep of,number
R2314 T8265 T8264 pobj axons,of
R2315 T8266 T8263 cc and,number
R2316 T8267 T8268 det the,extent
R2317 T8268 T8263 conj extent,number
R2318 T8269 T8268 prep of,extent
R2319 T8270 T8269 pobj growth,of
R2320 T8271 T8261 neg not,were
R2321 T8272 T8273 advmod as,robust
R2322 T8273 T8261 acomp robust,were
R2323 T8274 T8244 punct .,was
R2324 T8276 T8277 advmod Next,set
R2325 T8278 T8277 punct ", ",set
R2326 T8279 T8277 nsubj we,set
R2327 T8280 T8277 prt up,set
R2328 T8281 T8282 nmod E13,cultures
R2329 T8282 T8277 dobj cultures,set
R2330 T8283 T8282 nmod DRG,cultures
R2331 T8284 T8285 amod spinal,cord
R2332 T8285 T8282 compound cord,cultures
R2333 T8286 T8282 compound explant,cultures
R2334 T8287 T8277 advcl using,set
R2335 T8288 T8289 npadvmod NT,loaded
R2336 T8289 T8293 amod loaded,beads
R2337 T8290 T8288 punct -,NT
R2338 T8291 T8288 nummod 3,NT
R2339 T8292 T8289 punct -,loaded
R2340 T8293 T8287 dobj beads,using
R2341 T8294 T8293 acl placed,beads
R2342 T8295 T8294 prep at,placed
R2343 T8296 T8297 det the,midline
R2344 T8297 T8295 pobj midline,at
R2345 T8298 T8297 prep at,midline
R2346 T8299 T8300 amod mid-spinal,level
R2347 T8300 T8298 pobj level,at
R2348 T8301 T8300 compound cord,level
R2349 T8302 T8287 prep as,using
R2350 T8303 T8304 det an,source
R2351 T8304 T8302 pobj source,as
R2352 T8305 T8304 amod ectopic,source
R2353 T8306 T8304 nmod NT,source
R2354 T8307 T8306 punct -,NT
R2355 T8308 T8306 nummod 3,NT
R2356 T8309 T8310 punct (,15
R2357 T8310 T8277 parataxis 15,set
R2358 T8311 T8310 nsubj n,15
R2359 T8312 T8310 punct =,15
R2360 T8313 T8310 punct ),15
R2361 T8314 T8277 punct .,set
R2362 T8316 T8317 compound Control,cultures
R2363 T8317 T8318 nsubjpass cultures,set
R2364 T8319 T8318 auxpass were,set
R2365 T8320 T8318 advcl using,set
R2366 T8321 T8322 npadvmod PBS,loaded
R2367 T8322 T8324 amod loaded,beads
R2368 T8323 T8322 punct -,loaded
R2369 T8324 T8320 dobj beads,using
R2370 T8325 T8326 punct (,6
R2371 T8326 T8320 parataxis 6,using
R2372 T8327 T8326 nsubj n,6
R2373 T8328 T8326 punct =,6
R2374 T8329 T8326 punct ),6
R2375 T8330 T8318 punct .,set
R2376 T8332 T8333 compound DiI,labeling
R2377 T8333 T8334 nsubj labeling,revealed
R2378 T8335 T8333 prep through,labeling
R2379 T8336 T8337 det the,DRGs
R2380 T8337 T8335 pobj DRGs,through
R2381 T8338 T8339 amod numerous,fibers
R2382 T8339 T8334 dobj fibers,revealed
R2383 T8340 T8339 acl entering,fibers
R2384 T8341 T8342 det the,cord
R2385 T8342 T8340 dobj cord,entering
R2386 T8343 T8342 amod spinal,cord
R2387 T8344 T8340 prep at,entering
R2388 T8345 T8346 amod ectopic,regions
R2389 T8346 T8344 pobj regions,at
R2390 T8347 T8340 cc and,entering
R2391 T8348 T8340 conj growing,entering
R2392 T8349 T8348 prep towards,growing
R2393 T8350 T8351 det the,beads
R2394 T8351 T8349 pobj beads,towards
R2395 T8352 T8351 nmod NT,beads
R2396 T8353 T8352 punct -,NT
R2397 T8354 T8352 nummod 3,NT
R2398 T8355 T8356 punct (,6A
R2399 T8356 T8349 parataxis 6A,towards
R2400 T8357 T8356 compound Figure,6A
R2401 T8358 T8356 punct ),6A
R2402 T8359 T8340 punct ", ",entering
R2403 T8360 T8340 dep surrounding,entering
R2404 T8361 T8362 det the,beads
R2405 T8362 T8360 dobj beads,surrounding
R2406 T8363 T8360 cc and,surrounding
R2407 T8364 T8360 conj forming,surrounding
R2408 T8365 T8364 dobj bundles,forming
R2409 T8366 T8364 prep around,forming
R2410 T8367 T8366 pobj them,around
R2411 T8368 T8369 punct (,6C
R2412 T8369 T8334 parataxis 6C,revealed
R2413 T8370 T8369 compound Figure,6C
R2414 T8371 T8372 punct –,6E
R2415 T8372 T8369 prep 6E,6C
R2416 T8373 T8369 punct ),6C
R2417 T8374 T8334 punct .,revealed
R2418 T8376 T8377 prep In,directed
R2419 T8378 T8379 compound control,cultures
R2420 T8379 T8376 pobj cultures,In
R2421 T8380 T8377 punct ", ",directed
R2422 T8381 T8382 det all,fibers
R2423 T8382 T8377 nsubjpass fibers,directed
R2424 T8383 T8382 amod labeled,fibers
R2425 T8384 T8377 auxpass were,directed
R2426 T8385 T8377 prep towards,directed
R2427 T8386 T8387 det the,cord
R2428 T8387 T8385 pobj cord,towards
R2429 T8388 T8387 amod dorsal,cord
R2430 T8389 T8387 amod spinal,cord
R2431 T8390 T8377 cc and,directed
R2432 T8391 T8377 conj terminated,directed
R2433 T8392 T8391 advmod there,terminated
R2434 T8393 T8391 punct ", ",terminated
R2435 T8394 T8395 advmod where,enter
R2436 T8395 T8391 advcl enter,terminated
R2437 T8396 T8395 nsubj they,enter
R2438 T8397 T8395 advmod normally,enter
R2439 T8398 T8399 det the,matter
R2440 T8399 T8395 dobj matter,enter
R2441 T8400 T8399 amod gray,matter
R2442 T8401 T8395 prep at,enter
R2443 T8402 T8401 pobj E13,at
R2444 T8403 T8404 punct (,6B
R2445 T8404 T8391 parataxis 6B,terminated
R2446 T8405 T8404 compound Figure,6B
R2447 T8406 T8404 punct ),6B
R2448 T8407 T8377 punct .,directed
R2449 T8409 T8410 det No,axons
R2450 T8410 T8411 nsubjpass axons,observed
R2451 T8412 T8411 auxpass were,observed
R2452 T8413 T8411 prep around,observed
R2453 T8414 T8415 det the,beads
R2454 T8415 T8413 pobj beads,around
R2455 T8416 T8417 npadvmod PBS,loaded
R2456 T8417 T8415 amod loaded,beads
R2457 T8418 T8417 punct -,loaded
R2458 T8419 T8415 compound control,beads
R2459 T8420 T8421 punct (,6F
R2460 T8421 T8411 parataxis 6F,observed
R2461 T8422 T8421 compound Figure,6F
R2462 T8423 T8421 punct ),6F
R2463 T8424 T8411 punct .,observed
R2464 T8426 T8427 nsubj Axons,grow
R2465 T8428 T8429 dep that,enter
R2466 T8429 T8426 relcl enter,Axons
R2467 T8430 T8429 advmod normally,enter
R2468 T8431 T8432 det the,matter
R2469 T8432 T8429 dobj matter,enter
R2470 T8433 T8432 amod gray,matter
R2471 T8434 T8429 prep through,enter
R2472 T8435 T8436 amod dorsal,cord
R2473 T8436 T8434 pobj cord,through
R2474 T8437 T8436 amod spinal,cord
R2475 T8438 T8427 prep towards,grow
R2476 T8439 T8440 det the,midline
R2477 T8440 T8438 pobj midline,towards
R2478 T8441 T8442 advmod when,presented
R2479 T8442 T8427 advcl presented,grow
R2480 T8443 T8442 prep with,presented
R2481 T8444 T8445 det a,source
R2482 T8445 T8443 pobj source,with
R2483 T8446 T8445 amod localized,source
R2484 T8447 T8445 nmod NT,source
R2485 T8448 T8447 punct -,NT
R2486 T8449 T8447 nummod 3,NT
R2487 T8450 T8427 punct ", ",grow
R2488 T8451 T8427 cc and,grow
R2489 T8452 T8453 amod new,growth
R2490 T8453 T8455 nsubjpass growth,initiated
R2491 T8454 T8453 compound axon,growth
R2492 T8455 T8427 conj initiated,grow
R2493 T8456 T8453 prep towards,growth
R2494 T8457 T8458 det the,bead
R2495 T8458 T8456 pobj bead,towards
R2496 T8459 T8458 nmod NT,bead
R2497 T8460 T8459 punct -,NT
R2498 T8461 T8459 nummod 3,NT
R2499 T8462 T8455 auxpass is,initiated
R2500 T8463 T8455 prep from,initiated
R2501 T8464 T8463 pobj DRGs,from
R2502 T8465 T8455 punct ", ",initiated
R2503 T8466 T8455 advcl entering,initiated
R2504 T8467 T8468 det the,cord
R2505 T8468 T8466 dobj cord,entering
R2506 T8469 T8468 amod spinal,cord
R2507 T8470 T8466 prep at,entering
R2508 T8471 T8472 amod ectopic,loci
R2509 T8472 T8470 pobj loci,at
R2510 T8473 T8466 prep at,entering
R2511 T8474 T8475 amod lateral,cord
R2512 T8475 T8473 pobj cord,at
R2513 T8476 T8475 amod mid-spinal,cord
R2514 T8477 T8478 punct (,6G
R2515 T8478 T8466 parataxis 6G,entering
R2516 T8479 T8478 compound Figure,6G
R2517 T8480 T8478 punct ),6G
R2518 T8481 T8455 punct .,initiated
R2519 T8483 T8484 nsubj NT,is
R2520 T8485 T8483 punct -,NT
R2521 T8486 T8483 nummod 3,NT
R2522 T8487 T8484 advmod therefore,is
R2523 T8488 T8484 acomp capable,is
R2524 T8489 T8488 prep of,capable
R2525 T8490 T8489 pcomp acting,of
R2526 T8491 T8490 prep as,acting
R2527 T8492 T8493 det a,chemoattractant
R2528 T8493 T8491 pobj chemoattractant,as
R2529 T8494 T8493 prep for,chemoattractant
R2530 T8495 T8496 compound DRG,axons
R2531 T8496 T8494 pobj axons,for
R2532 T8497 T8484 punct .,is