PMC:529315 / 112-965 JSONTXT

Annnotations TAB JSON ListView MergeView

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/529315","sourcedb":"PMC","sourceid":"529315","source_url":"http://www.ncbi.nlm.nih.gov/pmc/529315","text":"Neurotrophin-3 (NT-3) is required for proprioceptive neuron survival. Deletion of the proapoptotic gene Bax in NT-3 knockout mice rescues these neurons and allows for examination of their axon growth in the absence of NT-3 signaling. TrkC-positive peripheral and central axons from dorsal root ganglia follow proper trajectories and arrive in close proximity to their targets but fail to innervate them. Peripherally, muscle spindles are absent and TrkC-positive axons do not enter their target muscles. Centrally, proprioceptive axons branch in ectopic regions of the spinal cord, even crossing the midline. In vitro assays reveal chemoattractant effects of NT-3 on dorsal root ganglion axons. Our results show that survival factor NT-3 acts as a short-distance axon guidance molecule for muscle sensory afferents as they approach their proper targets.","tracks":[{"project":"craft-ca-core-ex-dev","denotations":[{"id":"T370","span":{"begin":16,"end":20},"obj":"PR_EXT:000011459"},{"id":"T371","span":{"begin":38,"end":52},"obj":"GO:0019230"},{"id":"T372","span":{"begin":38,"end":59},"obj":"CL:1001451"},{"id":"T373","span":{"begin":70,"end":78},"obj":"SO_EXT:sequence_deletion_entity_or_process"},{"id":"T374","span":{"begin":89,"end":98},"obj":"GO_PATO_EXT:apoptotic_process_or_quality"},{"id":"T375","span":{"begin":99,"end":103},"obj":"SO_EXT:0000704"},{"id":"T376","span":{"begin":104,"end":107},"obj":"PR_EXT:000002193"},{"id":"T377","span":{"begin":111,"end":115},"obj":"PR_EXT:000011459"},{"id":"T378","span":{"begin":125,"end":129},"obj":"NCBITaxon:10088"},{"id":"T379","span":{"begin":130,"end":137},"obj":"SO_EXT:sequence_rescue_process"},{"id":"T380","span":{"begin":144,"end":151},"obj":"CL:0000540"},{"id":"T381","span":{"begin":188,"end":192},"obj":"GO:0030424"},{"id":"T382","span":{"begin":193,"end":199},"obj":"GO_EXT:biological_growth_entity_or_process"},{"id":"T383","span":{"begin":218,"end":222},"obj":"PR_EXT:000011459"},{"id":"T384","span":{"begin":223,"end":232},"obj":"GO_EXT:cell_communication_or_signaling_or_signal_transduction"},{"id":"T385","span":{"begin":234,"end":238},"obj":"PR_EXT:000011471"},{"id":"T386","span":{"begin":271,"end":276},"obj":"GO:0030424"},{"id":"T387","span":{"begin":282,"end":301},"obj":"UBERON:0000044"},{"id":"T388","span":{"begin":388,"end":397},"obj":"GO:0060384"},{"id":"T389","span":{"begin":418,"end":433},"obj":"UBERON:0003718"},{"id":"T390","span":{"begin":449,"end":453},"obj":"PR_EXT:000011471"},{"id":"T391","span":{"begin":463,"end":468},"obj":"GO:0030424"},{"id":"T392","span":{"begin":495,"end":502},"obj":"UBERON:0005090"},{"id":"T393","span":{"begin":515,"end":529},"obj":"GO:0019230"},{"id":"T394","span":{"begin":530,"end":535},"obj":"GO:0030424"},{"id":"T395","span":{"begin":554,"end":564},"obj":"_FRAGMENT"},{"id":"T396","span":{"begin":569,"end":580},"obj":"UBERON:0001948"},{"id":"T397","span":{"begin":600,"end":607},"obj":"UBERON:0009571"},{"id":"T398","span":{"begin":632,"end":647},"obj":"GO_EXT:chemoattractant_or_chemoattraction"},{"id":"T399","span":{"begin":659,"end":663},"obj":"PR_EXT:000011459"},{"id":"T400","span":{"begin":667,"end":687},"obj":"UBERON:0000044"},{"id":"T401","span":{"begin":688,"end":693},"obj":"GO:0030424"},{"id":"T402","span":{"begin":733,"end":737},"obj":"PR_EXT:000011459"},{"id":"T403","span":{"begin":763,"end":767},"obj":"GO:0030424"},{"id":"T404","span":{"begin":763,"end":776},"obj":"GO:0007411"},{"id":"T405","span":{"begin":777,"end":785},"obj":"CHEBI:36357"},{"id":"T406","span":{"begin":790,"end":796},"obj":"UBERON_EXT:muscle_structure_or_tissue"},{"id":"T407","span":{"begin":797,"end":804},"obj":"GO_EXT:detection_or_sensing_of_stimulus"}],"relations":[{"id":"R64","pred":"_lexicallyChainedTo","subj":"T396","obj":"T395"}],"attributes":[{"subj":"T370","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T371","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T372","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T373","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T374","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T375","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T376","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T377","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T378","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T379","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T380","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T381","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T382","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T383","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T384","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T385","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T386","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T387","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T388","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T389","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T390","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T391","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T392","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T393","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T394","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T395","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T396","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T397","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T398","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T399","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T400","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T401","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T402","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T403","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T404","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T405","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T406","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T407","pred":"source","obj":"craft-ca-core-ex-dev"}]},{"project":"craft-ca-core-dev","denotations":[{"id":"T334","span":{"begin":16,"end":20},"obj":"PR:000011459"},{"id":"T335","span":{"begin":38,"end":52},"obj":"GO:0019230"},{"id":"T336","span":{"begin":38,"end":59},"obj":"CL:1001451"},{"id":"T337","span":{"begin":99,"end":103},"obj":"SO:0000704"},{"id":"T338","span":{"begin":104,"end":107},"obj":"PR:000002193"},{"id":"T339","span":{"begin":111,"end":115},"obj":"PR:000011459"},{"id":"T340","span":{"begin":125,"end":129},"obj":"NCBITaxon:10088"},{"id":"T341","span":{"begin":144,"end":151},"obj":"CL:0000540"},{"id":"T342","span":{"begin":188,"end":192},"obj":"GO:0030424"},{"id":"T343","span":{"begin":218,"end":222},"obj":"PR:000011459"},{"id":"T344","span":{"begin":234,"end":238},"obj":"PR:000011471"},{"id":"T345","span":{"begin":271,"end":276},"obj":"GO:0030424"},{"id":"T346","span":{"begin":282,"end":301},"obj":"UBERON:0000044"},{"id":"T347","span":{"begin":388,"end":397},"obj":"GO:0060384"},{"id":"T348","span":{"begin":418,"end":433},"obj":"UBERON:0003718"},{"id":"T349","span":{"begin":449,"end":453},"obj":"PR:000011471"},{"id":"T350","span":{"begin":463,"end":468},"obj":"GO:0030424"},{"id":"T351","span":{"begin":495,"end":502},"obj":"UBERON:0005090"},{"id":"T352","span":{"begin":515,"end":529},"obj":"GO:0019230"},{"id":"T353","span":{"begin":530,"end":535},"obj":"GO:0030424"},{"id":"T354","span":{"begin":554,"end":564},"obj":"_FRAGMENT"},{"id":"T355","span":{"begin":569,"end":580},"obj":"UBERON:0001948"},{"id":"T356","span":{"begin":600,"end":607},"obj":"UBERON:0009571"},{"id":"T357","span":{"begin":659,"end":663},"obj":"PR:000011459"},{"id":"T358","span":{"begin":667,"end":687},"obj":"UBERON:0000044"},{"id":"T359","span":{"begin":688,"end":693},"obj":"GO:0030424"},{"id":"T360","span":{"begin":733,"end":737},"obj":"PR:000011459"},{"id":"T361","span":{"begin":763,"end":767},"obj":"GO:0030424"},{"id":"T362","span":{"begin":763,"end":776},"obj":"GO:0007411"},{"id":"T363","span":{"begin":777,"end":785},"obj":"CHEBI:36357"}],"relations":[{"id":"R63","pred":"_lexicallyChainedTo","subj":"T355","obj":"T354"}],"attributes":[{"subj":"T334","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T335","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T336","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T337","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T338","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T339","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T340","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T341","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T342","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T343","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T344","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T345","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T346","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T347","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T348","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T349","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T350","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T351","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T352","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T353","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T354","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T355","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T356","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T357","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T358","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T359","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T360","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T361","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T362","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T363","pred":"source","obj":"craft-ca-core-dev"}]},{"project":"craft-sa-dev","denotations":[{"id":"T428","span":{"begin":16,"end":18},"obj":"NN"},{"id":"T429","span":{"begin":18,"end":19},"obj":"HYPH"},{"id":"T430","span":{"begin":19,"end":20},"obj":"CD"},{"id":"T431","span":{"begin":20,"end":21},"obj":"-RRB-"},{"id":"T432","span":{"begin":22,"end":24},"obj":"VBZ"},{"id":"T433","span":{"begin":34,"end":37},"obj":"IN"},{"id":"T434","span":{"begin":38,"end":52},"obj":"JJ"},{"id":"T435","span":{"begin":53,"end":59},"obj":"NN"},{"id":"T436","span":{"begin":60,"end":68},"obj":"NN"},{"id":"T437","span":{"begin":68,"end":69},"obj":"."},{"id":"T438","span":{"begin":69,"end":233},"obj":"sentence"},{"id":"T439","span":{"begin":70,"end":78},"obj":"NN"},{"id":"T440","span":{"begin":130,"end":137},"obj":"VBZ"},{"id":"T441","span":{"begin":79,"end":81},"obj":"IN"},{"id":"T442","span":{"begin":82,"end":85},"obj":"DT"},{"id":"T443","span":{"begin":99,"end":103},"obj":"NN"},{"id":"T444","span":{"begin":86,"end":98},"obj":"JJ"},{"id":"T445","span":{"begin":104,"end":107},"obj":"NN"},{"id":"T446","span":{"begin":108,"end":110},"obj":"IN"},{"id":"T447","span":{"begin":111,"end":113},"obj":"NN"},{"id":"T448","span":{"begin":116,"end":124},"obj":"NN"},{"id":"T449","span":{"begin":113,"end":114},"obj":"HYPH"},{"id":"T450","span":{"begin":114,"end":115},"obj":"CD"},{"id":"T451","span":{"begin":125,"end":129},"obj":"NNS"},{"id":"T452","span":{"begin":138,"end":143},"obj":"DT"},{"id":"T453","span":{"begin":144,"end":151},"obj":"NNS"},{"id":"T454","span":{"begin":152,"end":155},"obj":"CC"},{"id":"T455","span":{"begin":156,"end":162},"obj":"VBZ"},{"id":"T456","span":{"begin":163,"end":166},"obj":"IN"},{"id":"T457","span":{"begin":167,"end":178},"obj":"NN"},{"id":"T458","span":{"begin":179,"end":181},"obj":"IN"},{"id":"T459","span":{"begin":182,"end":187},"obj":"PRP$"},{"id":"T460","span":{"begin":193,"end":199},"obj":"NN"},{"id":"T461","span":{"begin":188,"end":192},"obj":"NN"},{"id":"T462","span":{"begin":200,"end":202},"obj":"IN"},{"id":"T463","span":{"begin":203,"end":206},"obj":"DT"},{"id":"T464","span":{"begin":207,"end":214},"obj":"NN"},{"id":"T465","span":{"begin":215,"end":217},"obj":"IN"},{"id":"T466","span":{"begin":218,"end":220},"obj":"NN"},{"id":"T467","span":{"begin":223,"end":232},"obj":"NN"},{"id":"T468","span":{"begin":220,"end":221},"obj":"HYPH"},{"id":"T469","span":{"begin":221,"end":222},"obj":"CD"},{"id":"T470","span":{"begin":232,"end":233},"obj":"."},{"id":"T471","span":{"begin":233,"end":403},"obj":"sentence"},{"id":"T472","span":{"begin":234,"end":238},"obj":"NN"},{"id":"T473","span":{"begin":239,"end":247},"obj":"JJ"},{"id":"T474","span":{"begin":238,"end":239},"obj":"HYPH"},{"id":"T475","span":{"begin":271,"end":276},"obj":"NNS"},{"id":"T476","span":{"begin":248,"end":258},"obj":"JJ"},{"id":"T477","span":{"begin":259,"end":262},"obj":"CC"},{"id":"T478","span":{"begin":263,"end":270},"obj":"JJ"},{"id":"T479","span":{"begin":302,"end":308},"obj":"VBP"},{"id":"T480","span":{"begin":277,"end":281},"obj":"IN"},{"id":"T481","span":{"begin":282,"end":288},"obj":"JJ"},{"id":"T482","span":{"begin":289,"end":293},"obj":"NN"},{"id":"T483","span":{"begin":294,"end":301},"obj":"NNS"},{"id":"T484","span":{"begin":309,"end":315},"obj":"JJ"},{"id":"T485","span":{"begin":316,"end":328},"obj":"NNS"},{"id":"T486","span":{"begin":329,"end":332},"obj":"CC"},{"id":"T487","span":{"begin":333,"end":339},"obj":"VBP"},{"id":"T488","span":{"begin":340,"end":342},"obj":"IN"},{"id":"T489","span":{"begin":343,"end":348},"obj":"JJ"},{"id":"T490","span":{"begin":349,"end":358},"obj":"NN"},{"id":"T491","span":{"begin":359,"end":361},"obj":"IN"},{"id":"T492","span":{"begin":362,"end":367},"obj":"PRP$"},{"id":"T493","span":{"begin":368,"end":375},"obj":"NNS"},{"id":"T424","span":{"begin":25,"end":33},"obj":"VBN"},{"id":"T425","span":{"begin":12,"end":13},"obj":"HYPH"},{"id":"T426","span":{"begin":13,"end":14},"obj":"CD"},{"id":"T427","span":{"begin":15,"end":16},"obj":"-LRB-"},{"id":"T494","span":{"begin":376,"end":379},"obj":"CC"},{"id":"T495","span":{"begin":380,"end":384},"obj":"VBP"},{"id":"T496","span":{"begin":385,"end":387},"obj":"TO"},{"id":"T497","span":{"begin":388,"end":397},"obj":"VB"},{"id":"T498","span":{"begin":398,"end":402},"obj":"PRP"},{"id":"T499","span":{"begin":402,"end":403},"obj":"."},{"id":"T500","span":{"begin":403,"end":503},"obj":"sentence"},{"id":"T501","span":{"begin":404,"end":416},"obj":"RB"},{"id":"T502","span":{"begin":434,"end":437},"obj":"VBP"},{"id":"T503","span":{"begin":416,"end":418},"obj":","},{"id":"T504","span":{"begin":418,"end":424},"obj":"NN"},{"id":"T505","span":{"begin":425,"end":433},"obj":"NNS"},{"id":"T506","span":{"begin":438,"end":444},"obj":"JJ"},{"id":"T507","span":{"begin":445,"end":448},"obj":"CC"},{"id":"T508","span":{"begin":449,"end":453},"obj":"NN"},{"id":"T509","span":{"begin":454,"end":462},"obj":"JJ"},{"id":"T510","span":{"begin":453,"end":454},"obj":"HYPH"},{"id":"T511","span":{"begin":463,"end":468},"obj":"NNS"},{"id":"T512","span":{"begin":476,"end":481},"obj":"VB"},{"id":"T516","span":{"begin":495,"end":502},"obj":"NNS"},{"id":"T517","span":{"begin":488,"end":494},"obj":"NN"},{"id":"T513","span":{"begin":469,"end":471},"obj":"VBP"},{"id":"T518","span":{"begin":502,"end":503},"obj":"."},{"id":"T514","span":{"begin":472,"end":475},"obj":"RB"},{"id":"T515","span":{"begin":482,"end":487},"obj":"PRP$"},{"id":"T519","span":{"begin":503,"end":608},"obj":"sentence"},{"id":"T520","span":{"begin":504,"end":513},"obj":"RB"},{"id":"T521","span":{"begin":536,"end":542},"obj":"VBP"},{"id":"T522","span":{"begin":513,"end":515},"obj":","},{"id":"T523","span":{"begin":515,"end":529},"obj":"JJ"},{"id":"T524","span":{"begin":530,"end":535},"obj":"NNS"},{"id":"T525","span":{"begin":543,"end":545},"obj":"IN"},{"id":"T526","span":{"begin":546,"end":553},"obj":"JJ"},{"id":"T527","span":{"begin":554,"end":561},"obj":"NNS"},{"id":"T528","span":{"begin":562,"end":564},"obj":"IN"},{"id":"T529","span":{"begin":565,"end":568},"obj":"DT"},{"id":"T530","span":{"begin":576,"end":580},"obj":"NN"},{"id":"T531","span":{"begin":569,"end":575},"obj":"JJ"},{"id":"T532","span":{"begin":580,"end":582},"obj":","},{"id":"T533","span":{"begin":582,"end":586},"obj":"RB"},{"id":"T534","span":{"begin":587,"end":595},"obj":"VBG"},{"id":"T535","span":{"begin":596,"end":599},"obj":"DT"},{"id":"T536","span":{"begin":600,"end":607},"obj":"NN"},{"id":"T537","span":{"begin":607,"end":608},"obj":"."},{"id":"T538","span":{"begin":608,"end":694},"obj":"sentence"},{"id":"T539","span":{"begin":609,"end":611},"obj":"FW"},{"id":"T540","span":{"begin":612,"end":617},"obj":"FW"},{"id":"T541","span":{"begin":618,"end":624},"obj":"NNS"},{"id":"T542","span":{"begin":625,"end":631},"obj":"VBP"},{"id":"T543","span":{"begin":632,"end":647},"obj":"NN"},{"id":"T544","span":{"begin":648,"end":655},"obj":"NNS"},{"id":"T545","span":{"begin":656,"end":658},"obj":"IN"},{"id":"T546","span":{"begin":659,"end":661},"obj":"NN"},{"id":"T547","span":{"begin":661,"end":662},"obj":"HYPH"},{"id":"T548","span":{"begin":662,"end":663},"obj":"CD"},{"id":"T549","span":{"begin":664,"end":666},"obj":"IN"},{"id":"T550","span":{"begin":667,"end":673},"obj":"JJ"},{"id":"T551","span":{"begin":674,"end":678},"obj":"NN"},{"id":"T552","span":{"begin":679,"end":687},"obj":"NN"},{"id":"T553","span":{"begin":688,"end":693},"obj":"NNS"},{"id":"T554","span":{"begin":693,"end":694},"obj":"."},{"id":"T555","span":{"begin":694,"end":853},"obj":"sentence"},{"id":"T556","span":{"begin":695,"end":698},"obj":"PRP$"},{"id":"T557","span":{"begin":699,"end":706},"obj":"NNS"},{"id":"T558","span":{"begin":707,"end":711},"obj":"VBP"},{"id":"T559","span":{"begin":712,"end":716},"obj":"IN"},{"id":"T560","span":{"begin":738,"end":742},"obj":"VBZ"},{"id":"T561","span":{"begin":717,"end":725},"obj":"NN"},{"id":"T562","span":{"begin":726,"end":732},"obj":"NN"},{"id":"T563","span":{"begin":733,"end":735},"obj":"NN"},{"id":"T564","span":{"begin":735,"end":736},"obj":"HYPH"},{"id":"T565","span":{"begin":736,"end":737},"obj":"CD"},{"id":"T566","span":{"begin":743,"end":745},"obj":"IN"},{"id":"T567","span":{"begin":746,"end":747},"obj":"DT"},{"id":"T568","span":{"begin":777,"end":785},"obj":"NN"},{"id":"T569","span":{"begin":748,"end":753},"obj":"JJ"},{"id":"T570","span":{"begin":754,"end":762},"obj":"NN"},{"id":"T571","span":{"begin":753,"end":754},"obj":"HYPH"},{"id":"T572","span":{"begin":763,"end":767},"obj":"NN"},{"id":"T573","span":{"begin":768,"end":776},"obj":"NN"},{"id":"T574","span":{"begin":786,"end":789},"obj":"IN"},{"id":"T575","span":{"begin":790,"end":796},"obj":"NN"},{"id":"T576","span":{"begin":805,"end":814},"obj":"NNS"},{"id":"T577","span":{"begin":797,"end":804},"obj":"NN"},{"id":"T578","span":{"begin":815,"end":817},"obj":"IN"},{"id":"T579","span":{"begin":823,"end":831},"obj":"VBP"},{"id":"T580","span":{"begin":818,"end":822},"obj":"PRP"},{"id":"T581","span":{"begin":832,"end":837},"obj":"PRP$"},{"id":"T582","span":{"begin":845,"end":852},"obj":"NNS"},{"id":"T583","span":{"begin":838,"end":844},"obj":"JJ"},{"id":"T584","span":{"begin":852,"end":853},"obj":"."}],"relations":[{"id":"R2","pred":"punct","subj":"T429","obj":"T428"},{"id":"R3","pred":"nummod","subj":"T430","obj":"T428"},{"id":"R4","pred":"punct","subj":"T431","obj":"T424"},{"id":"R5","pred":"auxpass","subj":"T432","obj":"T424"},{"id":"R6","pred":"prep","subj":"T433","obj":"T424"},{"id":"R7","pred":"amod","subj":"T434","obj":"T435"},{"id":"R8","pred":"compound","subj":"T435","obj":"T436"},{"id":"R9","pred":"pobj","subj":"T436","obj":"T433"},{"id":"R10","pred":"punct","subj":"T437","obj":"T424"},{"id":"R11","pred":"nsubj","subj":"T439","obj":"T440"},{"id":"R12","pred":"prep","subj":"T441","obj":"T439"},{"id":"R13","pred":"det","subj":"T442","obj":"T443"},{"id":"R14","pred":"pobj","subj":"T443","obj":"T441"},{"id":"R15","pred":"amod","subj":"T444","obj":"T443"},{"id":"R16","pred":"appos","subj":"T445","obj":"T443"},{"id":"R17","pred":"prep","subj":"T446","obj":"T439"},{"id":"R18","pred":"nmod","subj":"T447","obj":"T448"},{"id":"R19","pred":"compound","subj":"T448","obj":"T451"},{"id":"R20","pred":"punct","subj":"T449","obj":"T447"},{"id":"R21","pred":"nummod","subj":"T450","obj":"T447"},{"id":"R22","pred":"pobj","subj":"T451","obj":"T446"},{"id":"R23","pred":"det","subj":"T452","obj":"T453"},{"id":"R24","pred":"dobj","subj":"T453","obj":"T440"},{"id":"R25","pred":"cc","subj":"T454","obj":"T440"},{"id":"R26","pred":"conj","subj":"T455","obj":"T440"},{"id":"R27","pred":"prep","subj":"T456","obj":"T455"},{"id":"R28","pred":"pobj","subj":"T457","obj":"T456"},{"id":"R29","pred":"prep","subj":"T458","obj":"T457"},{"id":"R30","pred":"poss","subj":"T459","obj":"T460"},{"id":"R31","pred":"pobj","subj":"T460","obj":"T458"},{"id":"R32","pred":"compound","subj":"T461","obj":"T460"},{"id":"R33","pred":"prep","subj":"T462","obj":"T455"},{"id":"R34","pred":"det","subj":"T463","obj":"T464"},{"id":"R35","pred":"pobj","subj":"T464","obj":"T462"},{"id":"R36","pred":"prep","subj":"T465","obj":"T464"},{"id":"R37","pred":"nmod","subj":"T466","obj":"T467"},{"id":"R38","pred":"pobj","subj":"T467","obj":"T465"},{"id":"R39","pred":"punct","subj":"T468","obj":"T466"},{"id":"R40","pred":"nummod","subj":"T469","obj":"T466"},{"id":"R41","pred":"punct","subj":"T470","obj":"T440"},{"id":"R42","pred":"npadvmod","subj":"T472","obj":"T473"},{"id":"R43","pred":"amod","subj":"T473","obj":"T475"},{"id":"R44","pred":"punct","subj":"T474","obj":"T473"},{"id":"R45","pred":"nsubj","subj":"T475","obj":"T479"},{"id":"R46","pred":"amod","subj":"T476","obj":"T475"},{"id":"R47","pred":"cc","subj":"T477","obj":"T476"},{"id":"R48","pred":"conj","subj":"T478","obj":"T476"},{"id":"R49","pred":"prep","subj":"T480","obj":"T475"},{"id":"R50","pred":"amod","subj":"T481","obj":"T482"},{"id":"R51","pred":"compound","subj":"T482","obj":"T483"},{"id":"R52","pred":"pobj","subj":"T483","obj":"T480"},{"id":"R53","pred":"amod","subj":"T484","obj":"T485"},{"id":"R54","pred":"dobj","subj":"T485","obj":"T479"},{"id":"R55","pred":"cc","subj":"T486","obj":"T479"},{"id":"R56","pred":"conj","subj":"T487","obj":"T479"},{"id":"R57","pred":"prep","subj":"T488","obj":"T487"},{"id":"R58","pred":"amod","subj":"T489","obj":"T490"},{"id":"R59","pred":"pobj","subj":"T490","obj":"T488"},{"id":"R60","pred":"prep","subj":"T491","obj":"T490"},{"id":"R61","pred":"poss","subj":"T492","obj":"T493"},{"id":"R62","pred":"pobj","subj":"T493","obj":"T491"},{"id":"R79","pred":"cc","subj":"T494","obj":"T479"},{"id":"R80","pred":"conj","subj":"T495","obj":"T479"},{"id":"R81","pred":"aux","subj":"T496","obj":"T497"},{"id":"R82","pred":"xcomp","subj":"T497","obj":"T495"},{"id":"R83","pred":"dobj","subj":"T498","obj":"T497"},{"id":"R84","pred":"punct","subj":"T499","obj":"T479"},{"id":"R85","pred":"advmod","subj":"T501","obj":"T502"},{"id":"R86","pred":"punct","subj":"T503","obj":"T502"},{"id":"R87","pred":"compound","subj":"T504","obj":"T505"},{"id":"R88","pred":"nsubj","subj":"T505","obj":"T502"},{"id":"R89","pred":"acomp","subj":"T506","obj":"T502"},{"id":"R90","pred":"cc","subj":"T507","obj":"T502"},{"id":"R91","pred":"npadvmod","subj":"T508","obj":"T509"},{"id":"R92","pred":"amod","subj":"T509","obj":"T511"},{"id":"R93","pred":"punct","subj":"T510","obj":"T509"},{"id":"R94","pred":"nsubj","subj":"T511","obj":"T512"},{"id":"R96","pred":"aux","subj":"T513","obj":"T512"},{"id":"R97","pred":"neg","subj":"T514","obj":"T512"},{"id":"R98","pred":"poss","subj":"T515","obj":"T516"},{"id":"R99","pred":"dobj","subj":"T516","obj":"T512"},{"id":"R100","pred":"compound","subj":"T517","obj":"T516"},{"id":"R101","pred":"punct","subj":"T518","obj":"T502"},{"id":"R102","pred":"advmod","subj":"T520","obj":"T521"},{"id":"R103","pred":"punct","subj":"T522","obj":"T521"},{"id":"R104","pred":"amod","subj":"T523","obj":"T524"},{"id":"R105","pred":"nsubj","subj":"T524","obj":"T521"},{"id":"R106","pred":"prep","subj":"T525","obj":"T521"},{"id":"R107","pred":"amod","subj":"T526","obj":"T527"},{"id":"R108","pred":"pobj","subj":"T527","obj":"T525"},{"id":"R109","pred":"prep","subj":"T528","obj":"T527"},{"id":"R110","pred":"det","subj":"T529","obj":"T530"},{"id":"R111","pred":"pobj","subj":"T530","obj":"T528"},{"id":"R112","pred":"amod","subj":"T531","obj":"T530"},{"id":"R113","pred":"punct","subj":"T532","obj":"T521"},{"id":"R114","pred":"advmod","subj":"T533","obj":"T534"},{"id":"R115","pred":"advcl","subj":"T534","obj":"T521"},{"id":"R116","pred":"det","subj":"T535","obj":"T536"},{"id":"R117","pred":"dobj","subj":"T536","obj":"T534"},{"id":"R118","pred":"punct","subj":"T537","obj":"T521"},{"id":"R119","pred":"advmod","subj":"T539","obj":"T540"},{"id":"R120","pred":"amod","subj":"T540","obj":"T541"},{"id":"R121","pred":"nsubj","subj":"T541","obj":"T542"},{"id":"R122","pred":"compound","subj":"T543","obj":"T544"},{"id":"R123","pred":"dobj","subj":"T544","obj":"T542"},{"id":"R124","pred":"prep","subj":"T545","obj":"T544"},{"id":"R125","pred":"pobj","subj":"T546","obj":"T545"},{"id":"R126","pred":"punct","subj":"T547","obj":"T546"},{"id":"R127","pred":"nummod","subj":"T548","obj":"T546"},{"id":"R128","pred":"prep","subj":"T549","obj":"T544"},{"id":"R129","pred":"amod","subj":"T550","obj":"T551"},{"id":"R130","pred":"compound","subj":"T551","obj":"T552"},{"id":"R131","pred":"compound","subj":"T552","obj":"T553"},{"id":"R132","pred":"pobj","subj":"T553","obj":"T549"},{"id":"R133","pred":"punct","subj":"T554","obj":"T542"},{"id":"R134","pred":"poss","subj":"T556","obj":"T557"},{"id":"R135","pred":"nsubj","subj":"T557","obj":"T558"},{"id":"R136","pred":"mark","subj":"T559","obj":"T560"},{"id":"R137","pred":"ccomp","subj":"T560","obj":"T558"},{"id":"R138","pred":"compound","subj":"T561","obj":"T562"},{"id":"R139","pred":"compound","subj":"T562","obj":"T563"},{"id":"R140","pred":"nsubj","subj":"T563","obj":"T560"},{"id":"R141","pred":"punct","subj":"T564","obj":"T563"},{"id":"R142","pred":"nummod","subj":"T565","obj":"T563"},{"id":"R143","pred":"prep","subj":"T566","obj":"T560"},{"id":"R144","pred":"det","subj":"T567","obj":"T568"},{"id":"R145","pred":"pobj","subj":"T568","obj":"T566"},{"id":"R146","pred":"amod","subj":"T569","obj":"T570"},{"id":"R147","pred":"compound","subj":"T570","obj":"T568"},{"id":"R148","pred":"punct","subj":"T571","obj":"T570"},{"id":"R149","pred":"compound","subj":"T572","obj":"T573"},{"id":"R150","pred":"compound","subj":"T573","obj":"T568"},{"id":"R151","pred":"prep","subj":"T574","obj":"T560"},{"id":"R152","pred":"compound","subj":"T575","obj":"T576"},{"id":"R153","pred":"pobj","subj":"T576","obj":"T574"},{"id":"R154","pred":"compound","subj":"T577","obj":"T576"},{"id":"R155","pred":"mark","subj":"T578","obj":"T579"},{"id":"R156","pred":"advcl","subj":"T579","obj":"T560"},{"id":"R157","pred":"nsubj","subj":"T580","obj":"T579"},{"id":"R158","pred":"poss","subj":"T581","obj":"T582"},{"id":"R159","pred":"dobj","subj":"T582","obj":"T579"},{"id":"R160","pred":"amod","subj":"T583","obj":"T582"},{"id":"R161","pred":"punct","subj":"T584","obj":"T558"},{"id":"R95","pred":"conj","subj":"T512","obj":"T502"}],"attributes":[{"subj":"T428","pred":"source","obj":"craft-sa-dev"},{"subj":"T429","pred":"source","obj":"craft-sa-dev"},{"subj":"T430","pred":"source","obj":"craft-sa-dev"},{"subj":"T431","pred":"source","obj":"craft-sa-dev"},{"subj":"T432","pred":"source","obj":"craft-sa-dev"},{"subj":"T433","pred":"source","obj":"craft-sa-dev"},{"subj":"T434","pred":"source","obj":"craft-sa-dev"},{"subj":"T435","pred":"source","obj":"craft-sa-dev"},{"subj":"T436","pred":"source","obj":"craft-sa-dev"},{"subj":"T437","pred":"source","obj":"craft-sa-dev"},{"subj":"T438","pred":"source","obj":"craft-sa-dev"},{"subj":"T439","pred":"source","obj":"craft-sa-dev"},{"subj":"T440","pred":"source","obj":"craft-sa-dev"},{"subj":"T441","pred":"source","obj":"craft-sa-dev"},{"subj":"T442","pred":"source","obj":"craft-sa-dev"},{"subj":"T443","pred":"source","obj":"craft-sa-dev"},{"subj":"T444","pred":"source","obj":"craft-sa-dev"},{"subj":"T445","pred":"source","obj":"craft-sa-dev"},{"subj":"T446","pred":"source","obj":"craft-sa-dev"},{"subj":"T447","pred":"source","obj":"craft-sa-dev"},{"subj":"T448","pred":"source","obj":"craft-sa-dev"},{"subj":"T449","pred":"source","obj":"craft-sa-dev"},{"subj":"T450","pred":"source","obj":"craft-sa-dev"},{"subj":"T451","pred":"source","obj":"craft-sa-dev"},{"subj":"T452","pred":"source","obj":"craft-sa-dev"},{"subj":"T453","pred":"source","obj":"craft-sa-dev"},{"subj":"T454","pred":"source","obj":"craft-sa-dev"},{"subj":"T455","pred":"source","obj":"craft-sa-dev"},{"subj":"T456","pred":"source","obj":"craft-sa-dev"},{"subj":"T457","pred":"source","obj":"craft-sa-dev"},{"subj":"T458","pred":"source","obj":"craft-sa-dev"},{"subj":"T459","pred":"source","obj":"craft-sa-dev"},{"subj":"T460","pred":"source","obj":"craft-sa-dev"},{"subj":"T461","pred":"source","obj":"craft-sa-dev"},{"subj":"T462","pred":"source","obj":"craft-sa-dev"},{"subj":"T463","pred":"source","obj":"craft-sa-dev"},{"subj":"T464","pred":"source","obj":"craft-sa-dev"},{"subj":"T465","pred":"source","obj":"craft-sa-dev"},{"subj":"T466","pred":"source","obj":"craft-sa-dev"},{"subj":"T467","pred":"source","obj":"craft-sa-dev"},{"subj":"T468","pred":"source","obj":"craft-sa-dev"},{"subj":"T469","pred":"source","obj":"craft-sa-dev"},{"subj":"T470","pred":"source","obj":"craft-sa-dev"},{"subj":"T471","pred":"source","obj":"craft-sa-dev"},{"subj":"T472","pred":"source","obj":"craft-sa-dev"},{"subj":"T473","pred":"source","obj":"craft-sa-dev"},{"subj":"T474","pred":"source","obj":"craft-sa-dev"},{"subj":"T475","pred":"source","obj":"craft-sa-dev"},{"subj":"T476","pred":"source","obj":"craft-sa-dev"},{"subj":"T477","pred":"source","obj":"craft-sa-dev"},{"subj":"T478","pred":"source","obj":"craft-sa-dev"},{"subj":"T479","pred":"source","obj":"craft-sa-dev"},{"subj":"T480","pred":"source","obj":"craft-sa-dev"},{"subj":"T481","pred":"source","obj":"craft-sa-dev"},{"subj":"T482","pred":"source","obj":"craft-sa-dev"},{"subj":"T483","pred":"source","obj":"craft-sa-dev"},{"subj":"T484","pred":"source","obj":"craft-sa-dev"},{"subj":"T485","pred":"source","obj":"craft-sa-dev"},{"subj":"T486","pred":"source","obj":"craft-sa-dev"},{"subj":"T487","pred":"source","obj":"craft-sa-dev"},{"subj":"T488","pred":"source","obj":"craft-sa-dev"},{"subj":"T489","pred":"source","obj":"craft-sa-dev"},{"subj":"T490","pred":"source","obj":"craft-sa-dev"},{"subj":"T491","pred":"source","obj":"craft-sa-dev"},{"subj":"T492","pred":"source","obj":"craft-sa-dev"},{"subj":"T493","pred":"source","obj":"craft-sa-dev"},{"subj":"T424","pred":"source","obj":"craft-sa-dev"},{"subj":"T425","pred":"source","obj":"craft-sa-dev"},{"subj":"T426","pred":"source","obj":"craft-sa-dev"},{"subj":"T427","pred":"source","obj":"craft-sa-dev"},{"subj":"T494","pred":"source","obj":"craft-sa-dev"},{"subj":"T495","pred":"source","obj":"craft-sa-dev"},{"subj":"T496","pred":"source","obj":"craft-sa-dev"},{"subj":"T497","pred":"source","obj":"craft-sa-dev"},{"subj":"T498","pred":"source","obj":"craft-sa-dev"},{"subj":"T499","pred":"source","obj":"craft-sa-dev"},{"subj":"T500","pred":"source","obj":"craft-sa-dev"},{"subj":"T501","pred":"source","obj":"craft-sa-dev"},{"subj":"T502","pred":"source","obj":"craft-sa-dev"},{"subj":"T503","pred":"source","obj":"craft-sa-dev"},{"subj":"T504","pred":"source","obj":"craft-sa-dev"},{"subj":"T505","pred":"source","obj":"craft-sa-dev"},{"subj":"T506","pred":"source","obj":"craft-sa-dev"},{"subj":"T507","pred":"source","obj":"craft-sa-dev"},{"subj":"T508","pred":"source","obj":"craft-sa-dev"},{"subj":"T509","pred":"source","obj":"craft-sa-dev"},{"subj":"T510","pred":"source","obj":"craft-sa-dev"},{"subj":"T511","pred":"source","obj":"craft-sa-dev"},{"subj":"T512","pred":"source","obj":"craft-sa-dev"},{"subj":"T516","pred":"source","obj":"craft-sa-dev"},{"subj":"T517","pred":"source","obj":"craft-sa-dev"},{"subj":"T513","pred":"source","obj":"craft-sa-dev"},{"subj":"T518","pred":"source","obj":"craft-sa-dev"},{"subj":"T514","pred":"source","obj":"craft-sa-dev"},{"subj":"T515","pred":"source","obj":"craft-sa-dev"},{"subj":"T519","pred":"source","obj":"craft-sa-dev"},{"subj":"T520","pred":"source","obj":"craft-sa-dev"},{"subj":"T521","pred":"source","obj":"craft-sa-dev"},{"subj":"T522","pred":"source","obj":"craft-sa-dev"},{"subj":"T523","pred":"source","obj":"craft-sa-dev"},{"subj":"T524","pred":"source","obj":"craft-sa-dev"},{"subj":"T525","pred":"source","obj":"craft-sa-dev"},{"subj":"T526","pred":"source","obj":"craft-sa-dev"},{"subj":"T527","pred":"source","obj":"craft-sa-dev"},{"subj":"T528","pred":"source","obj":"craft-sa-dev"},{"subj":"T529","pred":"source","obj":"craft-sa-dev"},{"subj":"T530","pred":"source","obj":"craft-sa-dev"},{"subj":"T531","pred":"source","obj":"craft-sa-dev"},{"subj":"T532","pred":"source","obj":"craft-sa-dev"},{"subj":"T533","pred":"source","obj":"craft-sa-dev"},{"subj":"T534","pred":"source","obj":"craft-sa-dev"},{"subj":"T535","pred":"source","obj":"craft-sa-dev"},{"subj":"T536","pred":"source","obj":"craft-sa-dev"},{"subj":"T537","pred":"source","obj":"craft-sa-dev"},{"subj":"T538","pred":"source","obj":"craft-sa-dev"},{"subj":"T539","pred":"source","obj":"craft-sa-dev"},{"subj":"T540","pred":"source","obj":"craft-sa-dev"},{"subj":"T541","pred":"source","obj":"craft-sa-dev"},{"subj":"T542","pred":"source","obj":"craft-sa-dev"},{"subj":"T543","pred":"source","obj":"craft-sa-dev"},{"subj":"T544","pred":"source","obj":"craft-sa-dev"},{"subj":"T545","pred":"source","obj":"craft-sa-dev"},{"subj":"T546","pred":"source","obj":"craft-sa-dev"},{"subj":"T547","pred":"source","obj":"craft-sa-dev"},{"subj":"T548","pred":"source","obj":"craft-sa-dev"},{"subj":"T549","pred":"source","obj":"craft-sa-dev"},{"subj":"T550","pred":"source","obj":"craft-sa-dev"},{"subj":"T551","pred":"source","obj":"craft-sa-dev"},{"subj":"T552","pred":"source","obj":"craft-sa-dev"},{"subj":"T553","pred":"source","obj":"craft-sa-dev"},{"subj":"T554","pred":"source","obj":"craft-sa-dev"},{"subj":"T555","pred":"source","obj":"craft-sa-dev"},{"subj":"T556","pred":"source","obj":"craft-sa-dev"},{"subj":"T557","pred":"source","obj":"craft-sa-dev"},{"subj":"T558","pred":"source","obj":"craft-sa-dev"},{"subj":"T559","pred":"source","obj":"craft-sa-dev"},{"subj":"T560","pred":"source","obj":"craft-sa-dev"},{"subj":"T561","pred":"source","obj":"craft-sa-dev"},{"subj":"T562","pred":"source","obj":"craft-sa-dev"},{"subj":"T563","pred":"source","obj":"craft-sa-dev"},{"subj":"T564","pred":"source","obj":"craft-sa-dev"},{"subj":"T565","pred":"source","obj":"craft-sa-dev"},{"subj":"T566","pred":"source","obj":"craft-sa-dev"},{"subj":"T567","pred":"source","obj":"craft-sa-dev"},{"subj":"T568","pred":"source","obj":"craft-sa-dev"},{"subj":"T569","pred":"source","obj":"craft-sa-dev"},{"subj":"T570","pred":"source","obj":"craft-sa-dev"},{"subj":"T571","pred":"source","obj":"craft-sa-dev"},{"subj":"T572","pred":"source","obj":"craft-sa-dev"},{"subj":"T573","pred":"source","obj":"craft-sa-dev"},{"subj":"T574","pred":"source","obj":"craft-sa-dev"},{"subj":"T575","pred":"source","obj":"craft-sa-dev"},{"subj":"T576","pred":"source","obj":"craft-sa-dev"},{"subj":"T577","pred":"source","obj":"craft-sa-dev"},{"subj":"T578","pred":"source","obj":"craft-sa-dev"},{"subj":"T579","pred":"source","obj":"craft-sa-dev"},{"subj":"T580","pred":"source","obj":"craft-sa-dev"},{"subj":"T581","pred":"source","obj":"craft-sa-dev"},{"subj":"T582","pred":"source","obj":"craft-sa-dev"},{"subj":"T583","pred":"source","obj":"craft-sa-dev"},{"subj":"T584","pred":"source","obj":"craft-sa-dev"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"craft-ca-core-ex-dev","color":"#eca993","default":true},{"id":"craft-ca-core-dev","color":"#9396ec"},{"id":"craft-sa-dev","color":"#b0ec93"}]}]}}