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PMC:529315 JSONTXT

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craft-ca-core-ex-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T5804 9306-9310 PR_EXT:000011459 denotes NT-3
T5805 9345-9356 GO_UBERON_EXT:innervation_entity_or_process denotes Innervation
T5806 9386-9397 GO_UBERON_EXT:innervation_entity_or_process denotes innervation
T5807 9411-9418 NCBITaxon:33208 denotes animals
T5808 9436-9443 UBERON:0003718 denotes spindle
T5809 9463-9483 UBERON:0001388 denotes gastrocnemius muscle
T5810 9485-9500 UBERON:0003718 denotes Muscle spindles
T5811 9534-9536 SO_EXT:wild_type_entity_or_quality denotes WT
T5812 9541-9544 PR_EXT:000002193 denotes Bax
T5813 9548-9555 NCBITaxon:33208 denotes animals
T5814 9611-9625 GO:0019230 denotes Proprioceptive
T5815 9633-9640 CHEBI_SO_EXT:molecular_label_or_mark_or_tag_process denotes labeled
T5816 9646-9659 GO:0005883 denotes neurofilament
T5817 9646-9661 PR_EXT:000011120 denotes neurofilament-M
T5818 9663-9665 GO:0005883 denotes NF
T5819 9663-9667 PR_EXT:000011120 denotes NF-M
T5820 9669-9677 GO:0042571 denotes antibody
T5821 9702-9709 GO_UBERON_EXT:nerve_ending_or_neuron_projection_terminus denotes endings
T5822 9747-9754 CHEBI_SO_EXT:molecular_label_or_mark_or_tag_process denotes labeled
T5823 9764-9772 GO:0042571 denotes antibody
T5824 9825-9832 CHEBI_PR_EXT:protein denotes protein
T5825 9890-9905 UBERON:0003718 denotes muscle spindles
T5826 9909-9913 PR_EXT:000011459 denotes NT-3
T5827 9917-9924 NCBITaxon:33208 denotes animals
T5828 9967-9970 PR_EXT:000002193 denotes Bax
T5829 9974-9981 NCBITaxon:33208 denotes animals
T5830 9991-9999 UBERON:0003718 denotes spindles
T5831 10005-10007 SO_EXT:wild_type_entity_or_quality denotes WT
T5832 10013-10021 UBERON:0003718 denotes spindles
T5833 10050-10057 NCBITaxon:33208 denotes animals
T5834 10063-10073 GO:0010467 denotes expressing
T5835 10074-10078 PR_EXT:000011459 denotes NT-3
T5836 10086-10092 UBERON_EXT:muscle_structure_or_tissue denotes muscle
T5837 10124-10128 PR_EXT:000011459 denotes NT-3
T5838 10139-10144 CL_GO_EXT:cell denotes cells
T5839 10150-10157 SO_EXT:sequence_rescue_process denotes rescued
T5840 10162-10177 UBERON:0003718 denotes muscle spindles
T5841 10199-10204 UBERON:0002101 denotes limbs
T5842 10239-10254 UBERON:0003718 denotes Muscle spindles
T5843 10278-10282 PR_EXT:000011471 denotes TrkC
T5844 10283-10291 GO:0042571 denotes antibody
T5845 10295-10297 SO_EXT:wild_type_entity_or_quality denotes WT
T5846 10302-10305 PR_EXT:000002193 denotes Bax
T5847 10309-10316 NCBITaxon:33208 denotes animals
T5848 10329-10333 PR_EXT:000011459 denotes NT-3
T5849 10369-10373 PR_EXT:000011459 denotes NT-3
T5850 10388-10395 NCBITaxon:33208 denotes animals
T5851 10397-10399 GO:0005883 denotes NF
T5852 10397-10401 PR_EXT:000011120 denotes NF-M
T5853 10402-10409 CHEBI_SO_EXT:molecular_label_or_mark_or_tag_process denotes labeled
T5854 10438-10445 UBERON:0005090 denotes muscles
T5855 10456-10463 UBERON:0005090 denotes muscles
T5856 10473-10480 NCBITaxon:33208 denotes animals
T5857 10511-10523 UBERON:0006134 denotes nerve fibers
T5858 10545-10549 PR_EXT:000011471 denotes TrkC
T5859 10575-10582 UBERON:0005090 denotes muscles
T5860 10604-10606 GO:0005883 denotes NF
T5861 10604-10608 PR_EXT:000011120 denotes NF-M
T5862 10609-10616 CHEBI_SO_EXT:molecular_label_or_mark_or_tag_process denotes labeled
T5863 10638-10643 GO_EXT:biological_movement_or_translocation_process denotes motor
T5864 10644-10649 GO:0030424 denotes axons
T5865 10662-10677 UBERON:0003718 denotes muscle spindles
T5866 10721-10736 GO_RO_EXT:developmental_differentiation_process denotes differentiation
T5867 10740-10754 GO:0019230 denotes proprioceptive
T5868 10755-10760 GO:0030424 denotes axons
T5869 10778-10788 GO_PATO_EXT:biological_maturation denotes maturation
T5870 10823-10827 PR_EXT:000011459 denotes NT-3
T5871 10893-10907 UBERON:0003718 denotes muscle spindle
T5872 10944-10946 GO:0005883 denotes NF
T5873 10944-10948 PR_EXT:000011120 denotes NF-M
T5874 10975-10978 CHEBI:52029 denotes DiI
T5875 10979-10987 CHEBI_SO_EXT:molecular_label_or_mark_or_tag_process denotes labeling
T5876 11027-11041 UBERON:0003718 denotes muscle spindle
T5877 11080-11089 SO_EXT:genotype_or_entity_with_genotype denotes genotypes
T5878 11139-11147 UBERON:0003718 denotes spindles
T5879 11178-11180 SO_EXT:wild_type_entity_or_quality denotes WT
T5880 11185-11188 PR_EXT:000002193 denotes Bax
T5881 11205-11209 PR_EXT:000011459 denotes NT-3
T5882 11213-11220 UBERON:0000922 denotes embryos
T5883 11234-11237 PR_EXT:000002193 denotes Bax
T5884 11238-11242 PR_EXT:000011459 denotes NT-3
T5885 11250-11254 SO_EXT:sequence_nullness denotes null
T5886 11255-11262 UBERON:0005090 denotes muscles
T5887 11278-11286 UBERON:0003718 denotes spindles
T5888 11315-11322 UBERON:0003718 denotes spindle
T5889 11354-11357 UBERON:0000978 denotes leg
T5890 11364-11370 UBERON:0000922 denotes embryo
T5891 11416-11419 CHEBI:52029 denotes DiI
T5892 11420-11428 CHEBI_SO_EXT:molecular_label_or_mark_or_tag_process denotes labeling
T5893 11483-11498 UBERON:0003718 denotes muscle spindles
T5894 11534-11536 SO_EXT:wild_type_entity_or_quality denotes WT
T5895 11541-11544 PR_EXT:000002193 denotes Bax
T5896 11545-11549 SO_EXT:sequence_nullness denotes null
T5897 11550-11557 UBERON:0005090 denotes muscles
T5898 11582-11586 PR_EXT:000011459 denotes NT-3
T5899 11600-11607 NCBITaxon:33208 denotes animals
T5900 11618-11621 CHEBI:52029 denotes DiI
T5901 11622-11629 CHEBI_SO_EXT:molecular_label_or_mark_or_tag_process denotes labeled
T5902 11665-11669 SO_EXT:sequence_nullness denotes null
T5903 11670-11677 UBERON:0005090 denotes muscles
T5904 11736-11751 UBERON:0003718 denotes muscle spindles
T5905 11770-11774 PR_EXT:000011469 denotes TrkA
T5906 11775-11779 PR_EXT:000011471 denotes TrkC
T5907 11780-11790 GO:0010467 denotes expression
T5908 11804-11816 UBERON:0001323 denotes tibial nerve
T5909 11832-11839 GO_EXT:detection_or_sensing_of_stimulus denotes sensory
T5910 11854-11874 UBERON:0001388 denotes gastrocnemius muscle
T5911 11890-11897 _FRAGMENT denotes skin of
T5912 11902-11911 UBERON:0004264 denotes lower leg
T5913 11916-11920 PR_EXT:000011459 denotes NT-3
T5914 11926-11930 PR_EXT:000011469 denotes TrkA
T5915 11940-11945 GO:0030424 denotes axons
T5916 11967-11979 UBERON:0001323 denotes tibial nerve
T5917 11998-12002 PR_EXT:000011471 denotes TrkC
T5918 12012-12017 GO:0030424 denotes axons
T5919 12032-12036 PR_EXT:000011469 denotes TrkA
T5920 12042-12046 PR_EXT:000011471 denotes TrkC
T5921 12047-12054 CHEBI_SO_EXT:molecular_label_or_mark_or_tag_process denotes labeled
T5922 12055-12060 GO:0030424 denotes axons
T5923 12081-12083 SO_EXT:wild_type_entity_or_quality denotes WT
T5924 12085-12088 PR_EXT:000002193 denotes Bax
T5925 12107-12114 NCBITaxon:33208 denotes animals
T5926 12164-12178 GO:0019230 denotes proprioceptive
T5927 12179-12184 GO:0030424 denotes axons
T5928 12222-12239 UBERON:0001021 denotes peripheral nerves
T5929 12254-12263 GO:0060384 denotes innervate
T5930 12277-12284 UBERON:0005090 denotes muscles
T5931 12303-12307 PR_EXT:000011459 denotes NT-3
T7773 13565-13569 PR_EXT:000011459 denotes NT-3
T7774 13575-13590 GO_EXT:0042056 denotes Chemoattractant
T7775 13595-13598 UBERON:0000044 denotes DRG
T7776 13599-13604 GO:0030424 denotes Axons
T7777 13642-13646 PR_EXT:000011459 denotes NT-3
T7778 13657-13672 GO_EXT:0042056 denotes chemoattractant
T7779 13677-13684 GO_EXT:detection_or_sensing_of_stimulus denotes sensory
T7780 13685-13690 GO:0030424 denotes axons
T7781 13734-13748 GO:0019230 denotes Proprioceptive
T7782 13749-13754 GO:0030424 denotes axons
T7841 15635-15638 CHEBI:52029 denotes DiI
T7783 13758-13762 NCBITaxon:10088 denotes mice
T7784 13773-13784 UBERON:0002315 denotes gray matter
T7785 13792-13803 UBERON:0002240 denotes spinal cord
T7786 13842-13849 UBERON:0009571 denotes midline
T7787 13871-13876 GO_EXT:biological_movement_or_translocation_process denotes motor
T7788 13871-13884 CL:0000100 denotes motor neurons
T7789 13932-13940 CHEBI_PR_EXT:collagen denotes collagen
T7790 13954-13956 SO_EXT:wild_type_entity_or_quality denotes WT
T7791 13957-13960 UBERON:0000044 denotes DRG
T7792 13975-13979 PR_EXT:000011459 denotes NT-3
T7793 14048-14054 NCBITaxon:27592 denotes bovine
T7794 14055-14060 UBERON:0001977 denotes serum
T7795 14055-14068 PR_EXT:000003918 denotes serum albumin
T7796 14079-14088 CHEBI_EXT:phosphate denotes phosphate
T7797 14089-14095 CHEBI_CHMO_EXT:buffer_solution denotes buffer
T7798 14096-14102 CHEBI_EXT:saline_solution denotes saline
T7799 14132-14135 UBERON:0000044 denotes DRG
T7800 14136-14141 GO:0030424 denotes axons
T7801 14170-14179 GO_PATO_EXT:biological_localization_process_or_quality denotes localized
T7802 14180-14184 PR_EXT:000011459 denotes NT-3
T7803 14256-14271 GO:0050918 denotes chemoattraction
T7804 14431-14435 PR_EXT:000011459 denotes NT-3
T7805 14444-14447 PR_EXT:000002193 denotes Bax
T7806 14448-14452 SO_EXT:sequence_nullness denotes null
T7807 14453-14460 UBERON:0000045 denotes ganglia
T7808 14480-14495 GO:0050918 denotes chemoattraction
T7809 14517-14521 PR_EXT:000011459 denotes NT-3
T7810 14545-14549 PR_EXT:000011471 denotes TrkC
T7811 14558-14564 PR_EXT:000001405 denotes p75NTR
T7812 14610-14613 UBERON:0000044 denotes DRG
T7813 14636-14642 PR_EXT:000001405 denotes p75NTR
T7814 14646-14650 NCBITaxon:10088 denotes mice
T7815 14661-14666 GO:0030424 denotes Axons
T7816 14676-14683 UBERON:0000045 denotes ganglia
T7817 14703-14718 GO:0050918 denotes chemoattraction
T7818 14731-14735 PR_EXT:000011459 denotes NT-3
T7819 14783-14787 PR_EXT:000011471 denotes TrkC
T7820 14788-14797 GO_EXT:0004872 denotes receptors
T7821 14798-14808 MOP:0000779 denotes conjugated
T7822 14812-14815 GO:0071735 denotes IgG
T7823 14834-14838 PR_EXT:000011471 denotes TrkC
T7824 14890-14894 PR_EXT:000011459 denotes NT-3
T7825 14904-14912 CHEBI_PR_EXT:collagen denotes collagen
T7826 14950-14954 PR_EXT:000011471 denotes TrkC
T7827 14962-14977 GO:0050918 denotes chemoattraction
T7828 15055-15059 PR_EXT:000011459 denotes NT-3
T7829 15151-15153 SO_EXT:wild_type_entity_or_quality denotes WT
T7830 15158-15162 UBERON:0000044 denotes DRGs
T7831 15217-15224 UBERON:0000045 denotes ganglia
T7832 15277-15283 GO_EXT:biological_growth_entity_or_process denotes growth
T7833 15366-15371 GO:0030424 denotes axons
T7834 15390-15396 GO_EXT:biological_growth_entity_or_process denotes growth
T7835 15437-15440 UBERON:0000044 denotes DRG
T7836 15441-15452 UBERON:0002240 denotes spinal cord
T7837 15476-15480 PR_EXT:000011459 denotes NT-3
T7838 15508-15515 UBERON:0009571 denotes midline
T7839 15523-15534 UBERON:0002240 denotes spinal cord
T7840 15555-15559 PR_EXT:000011459 denotes NT-3
T7842 15639-15647 CHEBI_SO_EXT:molecular_label_or_mark_or_tag_process denotes labeling
T7843 15660-15664 UBERON:0000044 denotes DRGs
T7844 15703-15714 UBERON:0002240 denotes spinal cord
T7845 15738-15745 GO:0040007 denotes growing
T7846 15758-15762 PR_EXT:000011459 denotes NT-3
T7847 15877-15884 CHEBI_SO_EXT:molecular_label_or_mark_or_tag_process denotes labeled
T7848 15897-15905 GO_EXT:biological_direction_or_guidance denotes directed
T7849 15925-15936 UBERON:0002240 denotes spinal cord
T7850 15989-16000 UBERON:0002315 denotes gray matter
T7851 16024-16029 GO:0030424 denotes axons
T7852 16093-16098 GO:0030424 denotes Axons
T7853 16123-16134 UBERON:0002315 denotes gray matter
T7854 16150-16161 UBERON:0002240 denotes spinal cord
T7855 16162-16166 GO:0040007 denotes grow
T7856 16179-16186 UBERON:0009571 denotes midline
T7857 16209-16218 GO_PATO_EXT:biological_localization_process_or_quality denotes localized
T7858 16219-16223 PR_EXT:000011459 denotes NT-3
T7859 16240-16244 GO:0030424 denotes axon
T7860 16245-16251 GO_EXT:biological_growth_entity_or_process denotes growth
T7861 16264-16268 PR_EXT:000011459 denotes NT-3
T7862 16292-16296 UBERON:0000044 denotes DRGs
T7863 16311-16322 UBERON:0002240 denotes spinal cord
T7864 16354-16365 UBERON:0002240 denotes spinal cord
T7865 16379-16383 PR_EXT:000011459 denotes NT-3
T7866 16420-16435 GO_EXT:0042056 denotes chemoattractant
T7867 16440-16443 UBERON:0000044 denotes DRG
T7868 16444-16449 GO:0030424 denotes axons
T12918 18335-18339 PR_EXT:000011459 denotes NT-3
T12919 18345-18360 GO_EXT:chemoattractant_or_chemoattraction denotes chemoattractant
T12920 18371-18378 GO_EXT:detection_or_sensing_of_stimulus denotes sensory
T12921 18383-18388 GO_EXT:biological_movement_or_translocation_process denotes motor
T12922 18389-18394 GO:0030424 denotes axons
T12923 18413-18428 GO_EXT:chemoattractant_or_chemoattraction denotes chemoattractant
T12924 18443-18452 UBERON:0000922 denotes embryonic
T12925 18453-18458 NCBITaxon:10088 denotes mouse
T12926 18459-18476 UBERON:0005868 denotes maxillary process
T12927 18480-18499 UBERON:0001675 denotes trigeminal ganglion
T12928 18500-18507 CL:0000540 denotes neurons
T12929 18555-18559 PR_EXT:000011459 denotes NT-3
T12930 18564-18569 UBERON:0000955 denotes brain
T12931 18564-18597 PR_EXT:000004716 denotes brain-derived neurotrophic factor
T12932 18578-18590 GO_EXT:neuron_development_or_generation denotes neurotrophic
T12933 18599-18603 PR_EXT:000004716 denotes BDNF
T12934 18683-18690 GO_EXT:detection_or_sensing_of_stimulus denotes sensory
T12935 18695-18700 GO_EXT:biological_movement_or_translocation_process denotes motor
T12936 18701-18706 GO:0030424 denotes axons
T12937 18710-18714 UBERON:0002101 denotes limb
T12938 18745-18749 GO:0040007 denotes grow
T12939 18758-18770 PR_EXT:000021998 denotes neurotrophin
T12940 18862-18874 PR_EXT:000021998 denotes neurotrophin
T12941 18893-18903 GO:0042571 denotes antibodies
T12942 18924-18931 GO_EXT:detection_or_sensing_of_stimulus denotes sensory
T12943 18936-18941 GO_EXT:biological_movement_or_translocation_process denotes motor
T12944 18942-18946 GO:0030424 denotes axon
T12945 18947-18953 GO_EXT:biological_growth_entity_or_process denotes growth
T12946 18966-18970 UBERON:0002101 denotes limb
T12947 18975-18985 SO_EXT:transgenic_entity denotes transgenic
T12948 18986-18990 NCBITaxon:10088 denotes mice
T12949 19003-19010 GO:0010467 denotes express
T12950 19011-19015 PR_EXT:000011459 denotes NT-3
T12951 19026-19032 PR_EXT:000011141 denotes nestin
T12952 19033-19041 SO_EXT:0000167 denotes promoter
T12953 19049-19071 UBERON:0001017 denotes central nervous system
T12954 19091-19105 GO:0019230 denotes proprioceptive
T12955 19132-19140 GO_EXT:biological_direction_or_guidance denotes directed
T12956 19189-19193 PR_EXT:000011459 denotes NT-3
T12957 19194-19204 GO:0010467 denotes expression
T12958 19212-19223 UBERON:0002240 denotes spinal cord
T12959 19298-19302 PR_EXT:000011459 denotes NT-3
T12960 19314-19329 GO_EXT:chemoattractant_or_chemoattraction denotes chemoattractant
T12961 19346-19357 GO_UBERON_EXT:innervation_entity_or_process denotes innervation
T12962 19361-19374 UBERON:0002257 denotes ventral horns
T12963 19378-19392 GO:0019230 denotes proprioceptive
T12964 19440-19454 GO:0019230 denotes proprioceptive
T12965 19480-19487 NCBITaxon:9031 denotes chicken
T12966 19488-19495 UBERON:0000922 denotes embryos
T12967 19535-19539 PR_EXT:000011459 denotes NT-3
T12968 19540-19548 GO:0042571 denotes antibody
T12969 19558-19569 UBERON:0002240 denotes spinal cord
T12970 19684-19692 GO:0042571 denotes antibody
T12971 19709-19713 PR_EXT:000011459 denotes NT-3
T12972 19724-19728 CL_GO_EXT:cell denotes cell
T12973 19888-19895 GO_EXT:detection_or_sensing_of_stimulus denotes sensory
T12974 19896-19901 GO:0030424 denotes axons
T12975 19948-19952 PR_EXT:000011459 denotes NT-3
T12976 19962-19972 GO:0010467 denotes expression
T12977 19976-19980 PR_EXT:000011459 denotes NT-3
T12978 19996-20005 GO_EXT:biological_routing_or_transport denotes targeting
T12979 20039-20051 PR_EXT:000021998 denotes neurotrophin
T12980 20060-20064 PR_EXT:000004716 denotes BDNF
T12981 20097-20112 GO_EXT:0042056 denotes chemoattractant
T12982 20117-20124 GO_EXT:detection_or_sensing_of_stimulus denotes sensory
T12983 20125-20130 GO:0030424 denotes axons
T12984 20131-20142 GO:0060384 denotes innervating
T12985 20143-20146 UBERON:0001690 denotes ear
T12986 20178-20182 SO_EXT:0000704 denotes gene
T12987 20183-20194 SO_EXT:sequence_substitution_entity_or_process denotes replacement
T12988 20213-20217 PR_EXT:000004716 denotes BDNF
T12989 20218-20228 GO:0010467 denotes expression
T12990 20247-20251 PR_EXT:000011459 denotes NT-3
T12991 20252-20260 SO_EXT:0000167 denotes promoter
T12992 20262-20272 UBERON_EXT:vestibule_or_vestibular_system denotes vestibular
T12993 20273-20278 GO:0030424 denotes axons
T12994 20281-20287 GO_EXT:biological_routing_or_transport denotes routed
T12995 20315-20319 PR_EXT:000004716 denotes BDNF
T12996 20327-20334 UBERON:0001844 denotes cochlea
T12997 20349-20358 GO:0010467 denotes expressed
T12998 20359-20363 PR_EXT:000011459 denotes NT-3
T12999 20377-20387 GO:0060384 denotes innervated
T13000 20397-20402 GO:0030424 denotes axons
T13001 20412-20416 PR_EXT:000011459 denotes NT-3
T13002 20450-20460 NCBITaxon:10508 denotes adenovirus
T13003 20470-20480 GO:0010467 denotes expression
T13004 20488-20495 GO_EXT:detection_or_sensing_of_stimulus denotes sensory
T13005 20496-20500 GO:0030424 denotes axon
T13006 20501-20507 GO_EXT:biological_growth_entity_or_process denotes growth
T13007 20515-20527 GO:0031099 denotes regeneration
T13008 20621-20627 GO:0030424 denotes axonal
T13009 20642-20655 UBERON:0002707 denotes corticospinal
T13010 20656-20661 GO:0030424 denotes axons
T13011 20673-20678 UBERON:0007023 denotes adult
T13012 20679-20690 UBERON:0002240 denotes spinal cord
T13013 20731-20736 GO:0030424 denotes axons
T13014 20768-20775 UBERON:0009571 denotes midline
T13015 20788-20792 PR_EXT:000011459 denotes NT-3
T13016 20826-20837 UBERON:0002240 denotes spinal cord
T13017 20935-20939 PR_EXT:000011459 denotes NT-3
T13018 20950-20965 GO_EXT:0042056 denotes chemoattractant
T13019 20970-20977 GO_EXT:detection_or_sensing_of_stimulus denotes sensory
T13020 21008-21013 GO_EXT:biological_movement_or_translocation_process denotes motor
T13021 21008-21020 CL:0000100 denotes motor neuron
T13022 21021-21032 GO_UBERON_EXT:innervation_entity_or_process denotes innervation
T13023 21037-21044 SO_EXT:sequence_rescue_process denotes rescued
T13024 21048-21052 PR_EXT:000011459 denotes NT-3
T13025 21056-21063 NCBITaxon:33208 denotes animals
T13026 21072-21082 GO:0010467 denotes expressing
T13027 21083-21087 PR_EXT:000011459 denotes NT-3
T13028 21109-21116 UBERON:0005090 denotes muscles
T13029 21166-21170 PR_EXT:000011459 denotes NT-3
T13030 21195-21203 SO_EXT:sequence_rescue_process denotes rescuing
T13031 21204-21218 GO:0019230 denotes proprioceptive
T13032 21204-21226 CL:1001451 denotes proprioceptive neurons
T13033 21230-21234 PR_EXT:000011459 denotes NT-3
T13034 21238-21245 NCBITaxon:33208 denotes animals
T13035 21257-21263 GO:0030424 denotes axonal
T13036 21257-21275 GO:0007411 denotes axonal pathfinding
T13037 21283-21294 UBERON:0002240 denotes spinal cord
T13038 21327-21331 PR_EXT:000011459 denotes NT-3
T13039 21359-21371 UBERON:0002240 denotes spinal cords
T13040 21381-21388 NCBITaxon:33208 denotes animals
T13041 21427-21432 GO_EXT:biological_movement_or_translocation_process denotes motor
T13042 21427-21440 CL:0000100 denotes motor neurons
T13043 21458-21467 GO_EXT:biological_routing_or_transport denotes transport
T13044 21468-21472 PR_EXT:000011459 denotes NT-3
T13045 21476-21482 UBERON_EXT:muscle_structure_or_tissue denotes muscle
T13046 21490-21501 UBERON:0002240 denotes spinal cord
T13047 21557-21561 PR_EXT:000011459 denotes NT-3
T13048 21580-21593 UBERON:0002257 denotes ventral horns
T13049 21603-21607 NCBITaxon:10088 denotes mice
T13050 21691-21694 PR_EXT:000002193 denotes Bax
T13051 21695-21699 PR_EXT:000011459 denotes NT-3
T13052 21710-21714 NCBITaxon:10088 denotes mice
T13053 21720-21724 GO_EXT:breeding denotes bred
T13054 21791-21805 GO:0019230 denotes proprioceptive
T13055 21879-21893 GO:0019230 denotes proprioceptive
T13056 21934-21945 UBERON:0002240 denotes spinal cord
T13057 22007-22009 PR_EXT:000013502 denotes PV
T13058 22029-22032 CHEBI:52029 denotes DiI
T13059 22033-22041 CHEBI_SO_EXT:molecular_label_or_mark_or_tag_process denotes labeling
T13060 22049-22066 UBERON:0001021 denotes peripheral nerves
T13061 22082-22084 PR_EXT:000013502 denotes PV
T13062 22121-22124 PR_EXT:000002193 denotes Bax
T13063 22125-22129 PR_EXT:000011459 denotes NT-3
T13064 22174-22187 PR_EXT:000021998 denotes neurotrophins
T13143 24138-24142 PR_EXT:000007223 denotes Er81
T13065 22211-22220 CHEBI_EXT:polyatomic_entity_or_group denotes molecular
T13066 22221-22228 CHEBI_SO_EXT:molecular_indicator_or_label_or_marker_or_tag denotes markers
T13067 22233-22247 GO:0019230 denotes proprioceptive
T13068 22248-22253 GO:0030424 denotes axons
T13069 22262-22264 PR_EXT:000013502 denotes PV
T13070 22268-22299 CHEBI_PR_EXT:calcitonin_gene_related_peptide denotes calcitonin gene-related peptide
T13071 22279-22283 SO_EXT:0000704 denotes gene
T13072 22292-22299 CHEBI_SO_EXT:peptide_or_peptide_region denotes peptide
T13073 22304-22309 UBERON:0001021 denotes nerve
T13074 22304-22323 PR_EXT:000011194 denotes nerve growth factor
T13075 22310-22316 GO_EXT:biological_growth_entity_or_process denotes growth
T13076 22310-22323 GO_EXT:0008083 denotes growth factor
T13077 22335-22340 GO:0030424 denotes axons
T13078 22406-22408 PR_EXT:000013502 denotes PV
T13079 22427-22430 PR_EXT:000002193 denotes Bax
T13080 22431-22435 PR_EXT:000011459 denotes NT-3
T13081 22475-22489 GO:0019230 denotes proprioceptive
T13082 22490-22495 GO:0030424 denotes axons
T13083 22552-22559 CHEBI_SO_EXT:molecular_label_or_mark_or_tag_process denotes labeled
T13084 22560-22580 UBERON:0001388 denotes gastrocnemius muscle
T13085 22611-22621 GO:0010467 denotes expressing
T13086 22622-22626 PR_EXT:000011471 denotes TrkC
T13087 22627-22630 CHEBI_SO_EXT:RNA denotes RNA
T13088 22638-22643 UBERON:0007023 denotes adult
T13089 22644-22647 NCBITaxon:10114 denotes rat
T13090 22648-22651 UBERON:0000044 denotes DRG
T13091 22702-22711 UBERON_EXT:zone_of_skin_or_skin_of_body denotes cutaneous
T13092 22712-22723 GO_UBERON_EXT:innervation_entity_or_process denotes innervation
T13093 22782-22786 PR_EXT:000011471 denotes TrkC
T13094 22787-22794 CHEBI_PR_EXT:protein denotes protein
T13095 22811-22820 UBERON_EXT:zone_of_skin_or_skin_of_body denotes cutaneous
T13096 22875-22883 GO_EXT:0004872 denotes receptor
T13097 22887-22896 GO:0010467 denotes expressed
T13098 22900-22909 UBERON_EXT:zone_of_skin_or_skin_of_body denotes cutaneous
T13099 22910-22915 GO:0030424 denotes axons
T13100 22966-22980 GO:0019230 denotes proprioceptive
T13101 22966-22988 CL:1001451 denotes proprioceptive neurons
T13102 22993-23003 GO_EXT:killing denotes eliminated
T13103 23007-23011 PR_EXT:000011459 denotes NT-3
T13104 23015-23019 PR_EXT:000011471 denotes TrkC
T13105 23020-23024 SO_EXT:sequence_nullness denotes null
T13106 23025-23029 NCBITaxon:10088 denotes mice
T13107 23045-23049 PR_EXT:000011471 denotes TrkC
T13108 23066-23078 UBERON:0001323 denotes tibial nerve
T13109 23097-23111 GO:0019230 denotes proprioceptive
T13110 23112-23117 GO:0030424 denotes axons
T13111 23206-23210 PR_EXT:000011459 denotes NT-3
T13112 23228-23234 UBERON_EXT:muscle_structure_or_tissue denotes muscle
T13113 23235-23246 GO_UBERON_EXT:innervation_entity_or_process denotes innervation
T13114 23251-23258 UBERON:0003718 denotes spindle
T13115 23259-23274 GO_RO_EXT:developmental_differentiation_process denotes differentiation
T13116 23282-23296 GO:0019230 denotes proprioceptive
T13117 23297-23302 GO:0030424 denotes axons
T13118 23333-23336 CHEBI:52029 denotes DiI
T13119 23337-23344 CHEBI_SO_EXT:molecular_label_or_mark_or_tag_process denotes labeled
T13120 23353-23356 UBERON:0000044 denotes DRG
T13121 23357-23362 GO:0030424 denotes axons
T13122 23370-23381 UBERON:0002240 denotes spinal cord
T13123 23437-23451 GO:0019230 denotes proprioceptive
T13124 23452-23457 GO:0030424 denotes axons
T13125 23483-23490 UBERON:0000957 denotes laminae
T13126 23511-23523 UBERON:0000934 denotes ventral cord
T13127 23547-23550 PR_EXT:000002193 denotes Bax
T13128 23551-23555 PR_EXT:000011459 denotes NT-3
T13129 23594-23597 CHEBI:52029 denotes DiI
T13130 23598-23606 CHEBI_SO_EXT:molecular_label_or_mark_or_tag_process denotes labeling
T13131 23646-23651 GO:0030424 denotes axons
T13132 23673-23684 UBERON:0002240 denotes spinal cord
T13133 23771-23776 GO:0030424 denotes axons
T13134 23790-23798 GO_UBERON_EXT:nerve_ending_or_neuron_projection_terminus denotes terminal
T13135 23790-23806 GO:0043195 denotes terminal boutons
T13136 23831-23838 CHEBI_SO_EXT:molecular_label_or_mark_or_tag_process denotes labeled
T13137 23909-23914 GO:0030424 denotes axons
T13138 23924-23939 UBERON:0009571 denotes ventral midline
T13139 23992-24000 GO_UBERON_EXT:nerve_ending_or_neuron_projection_terminus denotes terminal
T13140 23992-24008 GO:0043195 denotes terminal boutons
T13141 24115-24128 GO_EXT:transcription denotes transcription
T13142 24115-24136 GO_EXT:transcription_factor denotes transcription factors
T13144 24147-24151 PR_EXT:000007227 denotes Pea3
T13145 24157-24166 GO:0010467 denotes expressed
T13146 24170-24173 UBERON:0000044 denotes DRG
T13147 24174-24181 CL:0000540 denotes neurons
T13148 24193-24198 GO_EXT:biological_movement_or_translocation_process denotes motor
T13149 24193-24206 CL:0000100 denotes motor neurons
T13150 24224-24230 UBERON_EXT:muscle_structure_or_tissue denotes muscle
T13151 24224-24237 CL:0000187 denotes muscle fibers
T13152 24262-24273 UBERON:0002240 denotes spinal cord
T13153 24277-24281 PR_EXT:000007223 denotes Er81
T13154 24285-24289 NCBITaxon:10088 denotes mice
T13155 24299-24313 _FRAGMENT denotes projections of
T13156 24329-24334 GO:0030424 denotes axons
T13157 24314-24328 GO:0019230 denotes proprioceptive
T13158 24368-24373 GO:0030424 denotes axons
T13159 24389-24401 UBERON:0000934 denotes ventral cord
T13160 24470-24473 PR_EXT:000002193 denotes Bax
T13161 24474-24478 PR_EXT:000011459 denotes NT-3
T13162 24489-24493 NCBITaxon:10088 denotes mice
T13163 24522-24526 PR_EXT:000007223 denotes Er81
T13164 24530-24534 NCBITaxon:10088 denotes mice
T13165 24563-24567 PR_EXT:000011459 denotes NT-3
T13166 24576-24580 PR_EXT:000007223 denotes Er81
T13167 24581-24591 GO:0010467 denotes expression
T13168 24595-24598 UBERON:0000044 denotes DRG
T13169 24650-24654 PR_EXT:000007223 denotes Er81
T13170 24655-24659 CHEBI_SO_EXT:mRNA denotes mRNA
T13171 24660-24670 GO:0010467 denotes expression
T13172 24713-24717 PR_EXT:000011459 denotes NT-3
T13173 24725-24728 PR_EXT:000002193 denotes Bax
T13174 24729-24733 PR_EXT:000011459 denotes NT-3
T13175 24744-24748 NCBITaxon:10088 denotes mice
T13176 24799-24806 CHEBI_PR_EXT:protein denotes protein
T13177 24807-24817 GO:0010467 denotes expression
T13178 24835-24839 NCBITaxon:10088 denotes mice
T13179 24903-24906 UBERON:0000044 denotes DRG
T13180 24907-24912 CL_GO_EXT:cell denotes cells
T13181 24913-24920 GO:0010467 denotes express
T13182 24925-24938 GO_EXT:transcription denotes transcription
T13183 24925-24945 GO_EXT:transcription_factor denotes transcription factor
T13184 24946-24950 PR_EXT:000007223 denotes Er81
T13185 24966-24971 GO:0030424 denotes axons
T13186 24972-24976 GO:0040007 denotes grow
T13187 25015-25026 UBERON:0002240 denotes spinal cord
T13188 25030-25033 PR_EXT:000002193 denotes Bax
T13189 25034-25038 PR_EXT:000011459 denotes NT-3
T13190 25049-25053 NCBITaxon:10088 denotes mice
T13191 25078-25082 PR_EXT:000007223 denotes Er81
T13192 25086-25090 NCBITaxon:10088 denotes mice
T13193 25119-25133 GO:0019230 denotes proprioceptive
T13194 25134-25139 GO:0030424 denotes axons
T13195 25169-25180 UBERON:0002240 denotes spinal cord
T13196 25217-25222 GO:0030424 denotes axons
T13197 25259-25270 UBERON:0002240 denotes spinal cord
T13198 25275-25281 GO_EXT:biological_routing_or_transport denotes target
T13199 25298-25303 GO_EXT:biological_movement_or_translocation_process denotes motor
T13200 25298-25311 CL:0000100 denotes motor neurons
T13201 25394-25398 NCBITaxon:10088 denotes mice
T13202 25440-25445 GO_EXT:biological_movement_or_translocation_process denotes motor
T13203 25440-25453 CL:0000100 denotes motor neurons
T13204 25461-25473 UBERON:0000934 denotes ventral cord
T13205 25484-25488 NCBITaxon:10088 denotes mice
T13206 25489-25491 PR_EXT:000013502 denotes PV
T13207 25513-25518 GO:0030424 denotes axons
T13208 25526-25539 UBERON:0002257 denotes ventral horns
T13209 25571-25576 GO_EXT:biological_movement_or_translocation_process denotes motor
T13210 25571-25584 CL:0000100 denotes motor neurons
T13211 25605-25609 NCBITaxon:10088 denotes mice
T13212 25611-25615 PR_EXT:000011459 denotes NT-3
T13214 25659-25673 GO:0019230 denotes proprioceptive
T13215 25674-25679 GO:0030424 denotes axons
T13216 25693-25714 UBERON:0010405 denotes lateral motor columns
T13217 25701-25706 GO_EXT:biological_movement_or_translocation_process denotes motor
T13218 25759-25763 PR_EXT:000011459 denotes NT-3
T13219 25764-25768 CHEBI_SO_EXT:mRNA denotes mRNA
T13220 25772-25779 CHEBI_PR_EXT:protein denotes protein
T13221 25780-25789 GO:0010467 denotes expressed
T13222 25805-25816 UBERON:0002240 denotes spinal cord
T13223 25837-25842 GO_EXT:biological_movement_or_translocation_process denotes motor
T13224 25837-25850 CL:0000100 denotes motor neurons
T13225 25913-25917 NCBITaxon:10088 denotes mice
T13226 25919-25923 PR_EXT:000011459 denotes NT-3
T13227 25924-25934 GO:0010467 denotes expression
T13228 25950-25961 UBERON:0002240 denotes spinal cord
T13229 26023-26032 UBERON:0000922 denotes embryonic
T13230 26033-26037 NCBITaxon:10088 denotes mice
T13231 26047-26051 PR_EXT:000011459 denotes NT-3
T13232 26052-26056 CHEBI_SO_EXT:mRNA denotes mRNA
T13233 26064-26080 _FRAGMENT denotes ventral horns of
T13234 26085-26096 UBERON:0002257 denotes spinal cord
T13235 26133-26137 CHEBI_SO_EXT:mRNA denotes mRNA
T13236 26142-26149 CHEBI_PR_EXT:protein denotes protein
T13237 26154-26163 GO:0010467 denotes expressed
T13238 26174-26179 GO_EXT:biological_movement_or_translocation_process denotes motor
T13239 26174-26187 CL:0000100 denotes motor neurons
T13240 26196-26201 UBERON:0007023 denotes adult
T13241 26202-26213 UBERON:0002240 denotes spinal cord
T13242 26221-26226 GO_EXT:biological_movement_or_translocation_process denotes motor
T13243 26221-26234 CL:0000100 denotes motor neurons
T13244 26235-26242 GO:0010467 denotes express
T13245 26258-26262 PR_EXT:000011459 denotes NT-3
T13246 26270-26275 CL_GO_EXT:cell denotes cells
T13247 26287-26291 CL:0000125 denotes glia
T13248 26298-26305 GO:0010467 denotes express
T13249 26413-26423 SO_EXT:transgenic_entity denotes transgenic
T13250 26424-26428 NCBITaxon:10088 denotes mice
T13251 26434-26438 PR_EXT:000011459 denotes NT-3
T13252 26444-26454 GO:0010467 denotes expression
T13253 26466-26476 _FRAGMENT denotes regions of
T13254 26481-26492 UBERON:0001948 denotes spinal cord
T13255 26538-26542 PR_EXT:000011459 denotes NT-3
T13256 26546-26561 GO_EXT:chemoattractant_or_chemoattraction denotes chemoattractant
T13257 26562-26566 GO:0030424 denotes axon
T13258 26562-26575 GO:0007411 denotes axon guidance
T13259 26579-26593 GO:0019230 denotes proprioceptive
T13260 26594-26599 GO:0030424 denotes axons
T13261 26607-26618 UBERON:0002240 denotes spinal cord
T13262 26664-26679 GO:0050918 denotes chemoattraction
T13263 26683-26686 UBERON:0000044 denotes DRG
T13264 26687-26694 CL:0000540 denotes neurons
T13265 26698-26707 GO_PATO_EXT:biological_localization_process_or_quality denotes localized
T13266 26719-26723 PR_EXT:000011459 denotes NT-3
T13267 26730-26738 GO_EXT:reaction_or_response denotes response
T13268 26750-26752 SO_EXT:wild_type_entity_or_quality denotes WT
T13269 26754-26757 PR_EXT:000002193 denotes Bax
T13270 26758-26762 SO_EXT:sequence_nullness denotes null
T13271 26770-26773 PR_EXT:000001405 denotes p75
T13272 26774-26778 SO_EXT:sequence_nullness denotes null
T13273 26779-26782 UBERON:0000044 denotes DRG
T13274 26825-26838 PR_EXT:000021998 denotes neurotrophins
T13275 26857-26861 GO:0030424 denotes axon
T13276 26857-26870 GO:0007411 denotes axon guidance
T13277 26871-26880 CHEBI:36357 denotes molecules
T13278 26905-26912 GO_EXT:detection_or_sensing_of_stimulus denotes sensory
T13279 26913-26917 GO:0030424 denotes axon
T13280 26918-26926 GO_EXT:reaction_or_response denotes response
T13281 26930-26934 PR_EXT:000011459 denotes NT-3
T13282 27017-27021 PR_EXT:000011459 denotes NT-3
T13283 27047-27052 GO:0030424 denotes axons
T13284 27086-27094 CHEBI_PR_EXT:collagen denotes collagen
T13285 27120-27133 GO_PATO_EXT:physiological_process_or_quality denotes physiological
T13286 27160-27165 GO:0030424 denotes axons
T13287 27243-27247 PR_EXT:000011459 denotes NT-3
T13288 27270-27277 GO_EXT:detection_or_sensing_of_stimulus denotes sensory
T13289 27278-27283 GO:0030424 denotes axons
T13290 27309-27321 PR_EXT:000021998 denotes neurotrophin
T13291 27345-27351 GO:0030424 denotes axonal
T13292 27451-27459 GO:0045202 denotes synaptic
T13293 27468-27474 GO:0060004 denotes reflex
T13294 27489-27494 PR_EXT:000017442 denotes Wnt-3
T13295 27521-27525 GO:0030424 denotes axon
T13296 27553-27564 UBERON:0002240 denotes spinal cord
T13297 27596-27604 CHEBI:36357 denotes molecule
T13298 27606-27611 PR_EXT:000015235 denotes Slit2
T13299 27613-27622 GO:0010467 denotes expressed
T13300 27630-27637 UBERON:0009571 denotes midline
T13301 27645-27650 GO_EXT:biological_movement_or_translocation_process denotes motor
T13302 27645-27658 CL:0000100 denotes motor neurons
T13303 27701-27707 GO:0030424 denotes axonal
T13304 27780-27783 UBERON:0000044 denotes DRG
T13305 27784-27791 CL:0000540 denotes neurons
T13306 27792-27799 GO:0010467 denotes express
T13307 27800-27804 PR_EXT:ROBO denotes Robo
T13308 27805-27814 GO_EXT:0004872 denotes receptors
T13309 27822-27826 CHEMINF_GO_EXT:chemical_binding_or_bond_formation denotes bind
T13310 27830-27835 PR_EXT:SLIT denotes Slits
T13311 27841-27855 GO:0019230 denotes proprioceptive
T13312 27856-27861 GO:0030424 denotes axons
T13313 27887-27897 GO_EXT:reaction_or_response denotes responding
T13314 27901-27905 PR_EXT:SLIT denotes Slit
T13315 27934-27939 PR_EXT:000015235 denotes Slit2
T13316 27968-27972 PR_EXT:000011459 denotes NT-3
T13317 27984-27987 UBERON:0000044 denotes DRG
T13318 27988-27993 GO:0030424 denotes axons
T13319 28085-28095 UBERON:0001675 denotes trigeminal
T13320 28096-28101 GO:0030424 denotes axons
T13321 28109-28118 UBERON:0002298 denotes brainstem
T13322 28156-28161 PR_EXT:000015235 denotes Slit2
T13323 28188-28196 GO_UBERON_EXT:nerve_ending_or_neuron_projection_terminus denotes terminal
T13324 28210-28223 GO:0019230 denotes propioceptive
T13325 28224-28229 GO:0030424 denotes axons
T13326 28237-28249 UBERON:0000934 denotes ventral cord
T13327 28261-28268 UBERON:0009571 denotes midline
T13328 28315-28317 PR_EXT:000013502 denotes PV
T13329 28318-28328 GO:0010467 denotes expression
T13330 28332-28335 PR_EXT:000002193 denotes Bax
T13331 28336-28340 PR_EXT:000011459 denotes NT-3
T13332 28344-28348 NCBITaxon:10088 denotes mice
T13333 28363-28365 PR_EXT:000013502 denotes PV
T13334 28366-28376 GO:0010467 denotes expression
T13335 28409-28413 GO:0030424 denotes axon
T13336 28409-28423 GO:0007411 denotes axon targeting
T13337 28428-28442 UBERON:0003718 denotes muscle spindle
T13338 28443-28458 GO_RO_EXT:developmental_differentiation_process denotes differentiation
T13339 28541-28545 GO:0030424 denotes axon
T13340 28541-28557 GO:0007411 denotes axon pathfinding
T13341 28572-28580 GO:0045202 denotes synaptic
T13342 28581-28587 GO:0060004 denotes reflex
T13343 28598-28612 UBERON:0003718 denotes muscle spindle
T13344 28613-28628 GO_RO_EXT:developmental_differentiation_process denotes differentiation
T13345 28648-28650 PR_EXT:000013502 denotes PV
T13346 28654-28658 NCBITaxon:10088 denotes mice
T13347 28721-28729 GO_PATO_EXT:biological_behavior denotes behavior
T13348 28808-28814 GO:0030424 denotes axonal
T13349 28808-28824 GO:0007411 denotes axonal targeting
T13350 28836-28839 PR_EXT:000002193 denotes Bax
T13351 28840-28844 PR_EXT:000011459 denotes NT-3
T13352 28855-28859 NCBITaxon:10088 denotes mice
T13353 28892-28894 PR_EXT:000013502 denotes PV
T13354 28895-28905 GO:0010467 denotes expression
T13355 28909-28923 GO:0019230 denotes proprioceptive
T13356 28924-28929 CL_GO_EXT:cell denotes cells
T13357 28964-28968 PR_EXT:000011459 denotes NT-3
T13358 28991-28995 GO:0030424 denotes axon
T13359 28991-29004 GO:0007411 denotes axon guidance
T13360 29013-29027 GO:0019230 denotes proprioceptive
T13361 29028-29033 GO:0030424 denotes axons
T13362 29108-29112 GO:0030424 denotes axon
T13363 29108-29121 GO:0007411 denotes axon guidance
T13364 29150-29155 GO:0030424 denotes axons
T13365 29198-29202 PR_EXT:000011459 denotes NT-3
T13366 29223-29231 CHEBI:36357 denotes molecule
T13367 29253-29262 _FRAGMENT denotes targeting
T13368 29286-29302 GO:0097374 denotes of sensory axons
T13369 29267-29275 GO_UBERON_EXT:nerve_ending_or_neuron_projection_terminus denotes terminal
T13370 29297-29302 GO:0030424 denotes axons
T13371 29318-29329 UBERON:0002240 denotes spinal cord
T13372 29331-29335 PR_EXT:000011459 denotes NT-3
T13373 29378-29382 GO:0030424 denotes axon
T13374 29378-29391 GO:0007411 denotes axon guidance
T13375 29392-29401 CHEBI:36357 denotes molecules
T13376 29408-29418 GO:0065007 denotes regulating
T13377 29419-29429 GO:0010467 denotes expression
T13378 29454-29468 GO:0019230 denotes proprioceptive
T13379 29454-29475 CL:1001451 denotes proprioceptive neuron
T13380 29485-29494 GO_EXT:0004872 denotes receptors
T13381 29495-29502 CHEBI_GO_EXT:ligand denotes ligands
T13382 29516-29520 GO:0030424 denotes axon
T13383 29516-29529 GO:0007411 denotes axon guidance
T16172 29597-29600 PR_EXT:000002193 denotes Bax
T16173 29604-29611 PATO_UBERON_EXT:female_or_bearer_of_femaleness denotes females
T16174 29694-29698 PR_EXT:000011459 denotes NT-3
T16175 29712-29717 PATO_UBERON_EXT:male_or_bearer_of_maleness denotes males
T16176 29773-29780 NCBITaxon:33208 denotes animals
T16177 29818-29825 NCBITaxon:33208 denotes animals
T16178 29848-29853 SO_EXT:0000704 denotes genes
T16179 29859-29863 GO_EXT:breeding denotes bred
T16180 29890-29897 SO_EXT:0000112 denotes Primers
T16181 29911-29914 PR_EXT:000002193 denotes Bax
T16182 30033-30040 SO_EXT:0000112 denotes Primers
T16183 30054-30058 PR_EXT:000011459 denotes NT-3
T16184 30216-30218 SO_EXT:wild_type_entity_or_quality denotes WT
T16185 30220-30223 PR_EXT:000002193 denotes Bax
T16186 30232-30236 PR_EXT:000011459 denotes NT-3
T16187 30289-30292 PR_EXT:000002193 denotes Bax
T16188 30293-30297 PR_EXT:000011459 denotes NT-3
T16189 30308-30312 NCBITaxon:10088 denotes mice
T16190 30350-30354 NCBITaxon_UBERON_EXT:pup denotes pups
T16191 30360-30363 PR_EXT:000001405 denotes p75
T16192 30440-30444 UBERON:0002415 denotes tail
T16193 30445-30448 CHEBI_SO_EXT:DNA denotes DNA
T16194 30461-30468 NCBITaxon:33208 denotes animals
T16195 30479-30486 SO_EXT:0000112 denotes primers
T16196 30569-30572 CHEBI_GO_EXT:neomycin_or_neomycin_phosphotransferase denotes neo
T16197 30573-30580 SO_EXT:0000112 denotes primers
T16198 30666-30669 PR_EXT:000001405 denotes p75
T16199 30682-30691 UBERON:0000922 denotes embryonic
T16200 30712-30716 UBERON:0010148 denotes plug
T16201 30872-30878 NCBITaxon:33208 denotes Animal
T16202 30988-30995 NCBITaxon:33208 denotes animals
T16846 30998-31002 PR_EXT:000011469 denotes TrkA
T16847 31003-31007 PR_EXT:000011471 denotes TrkC
T16848 31037-31048 UBERON:0002240 denotes spinal cord
T16849 31104-31112 CHEBI:60004 denotes cocktail
T16850 31116-31122 NCBITaxon:9986 denotes rabbit
T16851 31128-31132 PR_EXT:000011469 denotes TrkA
T16852 31137-31141 NCBITaxon:9925 denotes goat
T16853 31147-31151 PR_EXT:000011471 denotes TrkC
T16854 31152-31162 GO:0042571 denotes antibodies
T16855 31221-31229 CHEBI:60004 denotes cocktail
T16856 31233-31236 CHEBI:37987 denotes CY3
T16857 31237-31247 MOP:0000779 denotes conjugated
T16858 31248-31254 NCBITaxon:9793 denotes donkey
T16859 31260-31266 NCBITaxon:9986 denotes rabbit
T16860 31271-31275 CHEBI:37926 denotes FITC
T16861 31276-31286 MOP:0000779 denotes conjugated
T16862 31287-31293 NCBITaxon:9793 denotes donkey
T16863 31299-31303 NCBITaxon:9925 denotes goat
T16864 31304-31314 GO:0042571 denotes antibodies
T16865 31387-31398 CHEBI:9750 denotes TritonX-100
T16866 31414-31420 NCBITaxon:9793 denotes donkey
T16867 31421-31426 UBERON:0001977 denotes serum
T16868 31432-31434 PR_EXT:000013502 denotes PV
T16869 31495-31500 NCBITaxon:10088 denotes mouse
T16870 31506-31508 PR_EXT:000013502 denotes PV
T16871 31509-31517 GO:0042571 denotes antibody
T16872 31587-31598 CHEBI:31624 denotes fluorescein
T16873 31599-31604 NCBITaxon:10088 denotes mouse
T16874 31608-31613 NCBITaxon:10088 denotes mouse
T16875 31709-31713 PR_EXT:000011469 denotes TrkA
T16876 31719-31723 PR_EXT:000011471 denotes TrkC
T16877 31724-31731 CHEBI_SO_EXT:molecular_label_or_mark_or_tag_process denotes labeled
T16878 31732-31737 CL_GO_EXT:cell denotes cells
T16879 31771-31779 SO_EXT:genotype_or_entity_with_genotype denotes genotype
T17326 31831-31845 UBERON:0003718 denotes Muscle spindle
T17327 31857-31877 UBERON:0001388 denotes Gastrocnemius muscle
T17328 31902-31906 NCBITaxon_UBERON_EXT:pup denotes pups
T17329 31966-31969 UBERON:0000978 denotes leg
T17330 31986-32006 UBERON:0001388 denotes gastrocnemius muscle
T17331 32012-32024 UBERON:0001323 denotes tibial nerve
T17332 32101-32109 GO:0042571 denotes antibody
T17333 32150-32157 UBERON:0003718 denotes spindle
T17334 32197-32204 SO_EXT:0001060 denotes isoform
T17335 32229-32234 NCBITaxon:10088 denotes mouse
T17336 32238-32243 NCBITaxon:10088 denotes mouse
T17337 32280-32286 NCBITaxon:9986 denotes rabbit
T17338 32292-32294 GO:0005883 denotes NF
T17339 32292-32296 PR_EXT:000011120 denotes NF-M
T17340 32297-32305 GO:0042571 denotes antibody
T17341 32321-32324 CHEBI:37987 denotes CY3
T17342 32325-32335 MOP:0000779 denotes conjugated
T17343 32336-32340 NCBITaxon:9925 denotes goat
T17344 32346-32352 NCBITaxon:9986 denotes rabbit
T17345 32353-32361 GO:0042571 denotes antibody
T17346 32396-32404 CHEBI_SO_EXT:molecular_label_or_mark_or_tag_process denotes labeling
T17347 32434-32437 CHEBI:52029 denotes DiI
T17348 32462-32466 UBERON:0000044 denotes DRGs
T17349 32474-32481 UBERON:0000922 denotes embryos
T17350 32497-32506 SO_EXT:genotype_or_entity_with_genotype denotes genotypes
T17351 32524-32544 UBERON:0001388 denotes gastrocnemius muscle
T17754 32613-32616 CHEBI:52029 denotes DiI
T17755 32617-32625 CHEBI_SO_EXT:molecular_label_or_mark_or_tag_process denotes labeling
T17756 32627-32639 UBERON:0002240 denotes Spinal cords
T17757 32668-32672 UBERON:0000044 denotes DRGs
T17758 32683-32688 GO_EXT:biological_movement_or_translocation_process denotes motor
T17759 32728-32733 GO_EXT:biological_movement_or_translocation_process denotes motor
T17760 32728-32741 CL:0000100 denotes motor neurons
T17761 32759-32825 CHEBI:52029 denotes 1,1′-dioctadecyl-3,3,3′,3′-tetramethylindocarbocyanine perchlorate
T17762 32827-32830 CHEBI:52029 denotes DiI
T17763 32832-32841 CHEBI_EXT:polyatomic_entity_or_group denotes Molecular
T17764 32842-32848 CHEBI_SO_EXT:molecular_probe denotes Probes
T17765 32898-32902 UBERON:0000044 denotes DRGs
T17766 32904-32911 CHEBI_SO_EXT:molecular_label_or_mark_or_tag_process denotes Labeled
T17767 32912-32924 UBERON:0002240 denotes spinal cords
T17768 33087-33098 GO_EXT:biological_movement_or_translocation_process denotes transferred
T17769 33238-33242 CHEBI:9754 denotes Tris
T17770 33243-33249 CHEBI_CHMO_EXT:buffer_solution denotes buffer
T18443 33288-33291 UBERON:0000044 denotes DRG
T18444 33334-33337 PR_EXT:000002193 denotes Bax
T18445 33338-33342 SO_EXT:sequence_nullness denotes null
T18446 33348-33351 PR_EXT:000001405 denotes p75
T18447 33352-33356 SO_EXT:sequence_nullness denotes null
T18448 33357-33362 NCBITaxon:10088 denotes mouse
T18449 33363-33370 UBERON:0000922 denotes embryos
T18450 33382-33390 CHEBI_PR_EXT:collagen denotes collagen
T18451 33406-33410 UBERON:0000044 denotes DRGs
T18452 33461-33469 CHEBI_EXT:tungsten denotes tungsten
T18453 33479-33487 CHEBI_PR_EXT:collagen denotes Collagen
T18454 33523-33531 CHEBI_PR_EXT:collagen denotes collagen
T18455 33559-33570 CHEBI:15366 denotes acetic acid
T18456 33676-33684 UBERON:0000045 denotes ganglion
T18457 33758-33766 CHEBI_PR_EXT:collagen denotes collagen
T18458 33916-33920 PR_EXT:000011459 denotes NT-3
T18459 34085-34097 PR_EXT:000021998 denotes neurotrophin
T18460 34194-34202 UBERON:0000045 denotes ganglion
T18461 34212-34220 CHEBI_PR_EXT:collagen denotes Collagen
T18462 34302-34307 UBERON:0001977 denotes Serum
T18463 34374-34376 SO_EXT:wild_type_entity_or_quality denotes WT
T18464 34377-34380 UBERON:0000044 denotes DRG
T18465 34404-34409 UBERON:0001977 denotes serum
T18466 34457-34461 PR_EXT:000011471 denotes TrkC
T18467 34476-34491 CHEBI_EXT:52217 denotes Pharmaceuticals
T19102 34596-34608 UBERON:0002240 denotes Spinal cords
T19103 34623-34627 UBERON:0000044 denotes DRGs
T19104 34666-34671 NCBITaxon:10088 denotes mouse
T19105 34672-34679 UBERON:0000922 denotes embryos
T19106 34728-34734 UBERON:0000479 denotes Tissue
T19107 34767-34773 UBERON:0000479 denotes Tissue
T19108 34843-34847 PR_EXT:000011459 denotes NT-3
T19109 34954-34961 UBERON:0009571 denotes midline
T19110 34969-34980 UBERON:0002240 denotes spinal cord
T19111 35032-35037 UBERON:0001977 denotes serum
T19112 35126-35129 CHEBI:16526 denotes CO2
T19113 35164-35180 CHEBI_EXT:paraformaldehye denotes paraformaldehyde
T19114 35211-35214 CHEBI:52029 denotes DiI
T19115 35236-35240 UBERON:0000044 denotes DRGs
T19116 35300-35303 CHEBI_EXT:37958 denotes dye
T364 2-17 GO_EXT:chemoattractant_or_chemoattraction denotes Chemoattractant
T365 27-31 PR_EXT:000011459 denotes NT-3
T366 35-49 GO:0019230 denotes Proprioceptive
T367 50-54 GO:0030424 denotes Axon
T368 50-63 GO:0007411 denotes Axon Guidance
T369 64-126 PR_EXT:000011459 denotes NT-3 and Proprioceptive Axon Guidance Abstract Neurotrophin-3
T370 128-132 PR_EXT:000011459 denotes NT-3
T371 150-164 GO:0019230 denotes proprioceptive
T372 150-171 CL:1001451 denotes proprioceptive neuron
T373 182-190 SO_EXT:sequence_deletion_entity_or_process denotes Deletion
T374 201-210 GO_PATO_EXT:apoptotic_process_or_quality denotes apoptotic
T375 211-215 SO_EXT:0000704 denotes gene
T376 216-219 PR_EXT:000002193 denotes Bax
T377 223-227 PR_EXT:000011459 denotes NT-3
T378 237-241 NCBITaxon:10088 denotes mice
T379 242-249 SO_EXT:sequence_rescue_process denotes rescues
T380 256-263 CL:0000540 denotes neurons
T381 300-304 GO:0030424 denotes axon
T382 305-311 GO_EXT:biological_growth_entity_or_process denotes growth
T383 330-334 PR_EXT:000011459 denotes NT-3
T384 335-344 GO_EXT:cell_communication_or_signaling_or_signal_transduction denotes signaling
T385 346-350 PR_EXT:000011471 denotes TrkC
T386 383-388 GO:0030424 denotes axons
T387 394-413 UBERON:0000044 denotes dorsal root ganglia
T388 500-509 GO:0060384 denotes innervate
T389 530-545 UBERON:0003718 denotes muscle spindles
T390 561-565 PR_EXT:000011471 denotes TrkC
T391 575-580 GO:0030424 denotes axons
T392 607-614 UBERON:0005090 denotes muscles
T393 627-641 GO:0019230 denotes proprioceptive
T394 642-647 GO:0030424 denotes axons
T395 666-676 _FRAGMENT denotes regions of
T396 681-692 UBERON:0001948 denotes spinal cord
T397 712-719 UBERON:0009571 denotes midline
T398 744-759 GO_EXT:chemoattractant_or_chemoattraction denotes chemoattractant
T399 771-775 PR_EXT:000011459 denotes NT-3
T400 779-799 UBERON:0000044 denotes dorsal root ganglion
T401 800-805 GO:0030424 denotes axons
T402 845-849 PR_EXT:000011459 denotes NT-3
T403 875-879 GO:0030424 denotes axon
T404 875-888 GO:0007411 denotes axon guidance
T405 889-897 CHEBI:36357 denotes molecule
T406 902-908 UBERON_EXT:muscle_structure_or_tissue denotes muscle
T407 909-916 GO_EXT:detection_or_sensing_of_stimulus denotes sensory
T1122 1100-1114 PR_EXT:000011459 denotes Neurotrophin-3
T1123 1116-1120 PR_EXT:000011459 denotes NT-3
T1124 1166-1180 GO:0019230 denotes proprioceptive
T1125 1191-1196 GO_EXT:biological_movement_or_translocation_process denotes motor
T1126 1191-1204 CL:0000100 denotes motor neurons
T1127 1246-1250 NCBITaxon:10088 denotes Mice
T1128 1264-1268 PR_EXT:000011459 denotes NT-3
T1129 1274-1282 CHEBI_SO_EXT:tyrosine denotes tyrosine
T1130 1274-1298 GO_EXT:0019199 denotes tyrosine kinase receptor
T1131 1300-1304 PR_EXT:000011471 denotes TrkC
T1132 1312-1316 PR_EXT:000011471 denotes TrkC
T1133 1326-1332 CL:0000540 denotes neuron
T1134 1342-1355 GO_EXT:transcription denotes transcription
T1135 1342-1362 GO_EXT:transcription_factor denotes transcription factor
T1136 1363-1368 PR_EXT:000014365 denotes Runx3
T1137 1422-1437 UBERON:0003718 denotes muscle spindles
T1138 1451-1465 GO:0019230 denotes proprioceptive
T1139 1451-1473 CL:1001451 denotes proprioceptive neurons
T1140 1477-1496 UBERON:0000044 denotes dorsal root ganglia
T1141 1498-1502 UBERON:0000044 denotes DRGs
T1142 1513-1518 GO:0030424 denotes axons
T1143 1665-1669 PR_EXT:000011459 denotes NT-3
T1144 1673-1682 GO:0010467 denotes expressed
T1145 1698-1709 UBERON:0002240 denotes spinal cord
T1146 1729-1738 UBERON:0004347 denotes limb buds
T1147 1772-1787 UBERON:0003718 denotes muscle spindles
T1148 1880-1887 GO_EXT:detection_or_sensing_of_stimulus denotes sensory
T1149 1888-1893 GO:0030424 denotes axons
T1150 1913-1921 CL:0002372 denotes myotubes
T1151 1935-1949 UBERON:0003718 denotes muscle spindle
T1152 1950-1965 GO_RO_EXT:developmental_differentiation_process denotes differentiation
T1153 1992-2005 GO_UBERON_EXT:nerve_ending_or_neuron_projection_terminus denotes nerve endings
T1154 1998-2005 GO_UBERON_EXT:nerve_ending_or_neuron_projection_terminus denotes endings
T1155 2026-2033 NCBITaxon:9031 denotes chicken
T1156 2034-2040 UBERON:0000922 denotes embryo
T1157 2042-2046 UBERON:0002101 denotes limb
T1158 2065-2069 PR_EXT:000011459 denotes NT-3
T1159 2070-2078 GO:0042571 denotes antibody
T1160 2095-2104 UBERON:0004347 denotes limb buds
T1161 2113-2124 GO_EXT:killing denotes elimination
T1162 2128-2132 PR_EXT:000011471 denotes TrkC
T1163 2142-2149 CL:0000540 denotes neurons
T1164 2164-2175 GO_UBERON_EXT:innervation_entity_or_process denotes innervation
T1165 2179-2184 GO_EXT:biological_movement_or_translocation_process denotes motor
T1166 2179-2192 CL:0000100 denotes motor neurons
T1167 2224-2228 PR_EXT:000011459 denotes NT-3
T1168 2269-2275 UBERON_EXT:muscle_structure_or_tissue denotes muscle
T1169 2276-2283 GO_EXT:detection_or_sensing_of_stimulus denotes sensory
T1170 2354-2368 GO_UBERON_EXT:proprioceptor denotes proprioceptors
T1171 2402-2410 GO:0045202 denotes synaptic
T1172 2411-2417 GO:0060004 denotes reflex
T1173 2453-2457 PR_EXT:000011459 denotes NT-3
T1174 2468-2483 GO_EXT:0042056 denotes chemoattractant
T1175 2488-2495 GO_EXT:detection_or_sensing_of_stimulus denotes sensory
T1176 2496-2501 GO:0030424 denotes axons
T1177 2541-2549 GO_EXT:biological_direction_or_guidance denotes directed
T2233 2573-2577 PR_EXT:000011471 denotes TrkC
T2234 2587-2590 UBERON:0000044 denotes DRG
T2235 2591-2598 CL:0000540 denotes Neurons
T2236 2603-2610 SO_EXT:sequence_rescue_process denotes Rescued
T2237 2614-2617 PR_EXT:000002193 denotes Bax
T2238 2618-2622 PR_EXT:000011459 denotes NT-3
T2239 2639-2643 NCBITaxon:10088 denotes Mice
T2240 2644-2648 NCBITaxon:10088 denotes Mice
T2241 2660-2669 GO_PATO_EXT:apoptotic_process_or_quality denotes apoptotic
T2242 2670-2677 CHEBI_PR_EXT:protein denotes protein
T2243 2678-2681 PR_EXT:000002193 denotes Bax
T2244 2727-2740 PR_EXT:000021998 denotes neurotrophins
T2245 2761-2764 PR_EXT:000002193 denotes Bax
T2246 2775-2782 GO_EXT:detection_or_sensing_of_stimulus denotes sensory
T2247 2775-2790 CL:0000101 denotes sensory neurons
T2248 2809-2822 PR_EXT:000021998 denotes neurotrophins
T2249 2909-2915 GO:0030424 denotes axonal
T2250 2928-2932 GO_EXT:breeding denotes bred
T2251 2933-2937 PR_EXT:000011459 denotes NT-3
T2252 2955-2958 PR_EXT:000002193 denotes Bax
T2253 2973-2977 NCBITaxon:10088 denotes mice
T2254 2988-2992 NCBITaxon:10088 denotes mice
T2255 3016-3020 PR_EXT:000011459 denotes NT-3
T2256 3025-3028 PR_EXT:000002193 denotes Bax
T2257 3029-3034 SO_EXT:0000704 denotes genes
T2258 3049-3063 GO:0019230 denotes proprioceptive
T2259 3064-3082 GO:0030424 denotes axonal projections
T2260 3088-3092 PR_EXT:000011459 denotes NT-3
T2261 3108-3112 GO:0016265 denotes died
T2262 3131-3136 GO:0007567 denotes birth
T2263 3176-3180 PR_EXT:000011469 denotes TrkA
T2264 3181-3185 PR_EXT:000011471 denotes TrkC
T2265 3262-3270 CHEBI_PR_EXT:protein denotes proteins
T2266 3291-3295 PR_EXT:000011471 denotes TrkC
T2267 3305-3310 CL_GO_EXT:cell denotes cells
T2268 3361-3365 PR_EXT:000011459 denotes NT-3
T2269 3373-3382 UBERON:0000922 denotes embryonic
T2270 3410-3413 UBERON:0000044 denotes DRG
T2271 3414-3419 CL_GO_EXT:cell denotes cells
T2272 3420-3430 GO:0010467 denotes expressing
T2273 3438-3442 PR_EXT:000011469 denotes TrkA
T2274 3446-3450 PR_EXT:000011471 denotes TrkC
T2275 3491-3500 SO_EXT:wild_type_entity_or_quality denotes wild-type
T2276 3502-3504 SO_EXT:wild_type_entity_or_quality denotes WT
T2277 3509-3512 PR_EXT:000002193 denotes Bax
T2278 3516-3523 NCBITaxon:33208 denotes animals
T2279 3546-3551 GO:0007567 denotes natal
T2280 3569-3574 CL_GO_EXT:cell denotes cells
T2281 3575-3584 GO:0010467 denotes expressed
T2282 3585-3589 PR_EXT:000011471 denotes TrkC
T2283 3598-3602 PR_EXT:000011459 denotes NT-3
T2284 3606-3613 NCBITaxon:33208 denotes animals
T2285 3621-3624 PR_EXT:000002193 denotes Bax
T2286 3625-3626 SO_EXT:normal_or_wild_type_or_present denotes +
T2287 3627-3628 SO_EXT:normal_or_wild_type_or_present denotes +
T2288 3629-3636 SO_EXT:0000704 denotes genetic
T2289 3658-3663 CL_GO_EXT:cell denotes cells
T2290 3667-3676 GO:0010467 denotes expressed
T2291 3677-3681 PR_EXT:000011469 denotes TrkA
T2292 3686-3690 PR_EXT:000011471 denotes TrkC
T2293 3710-3718 SO_EXT:genotype_or_entity_with_genotype denotes genotype
T2294 3791-3795 PR_EXT:000011469 denotes TrkA
T2295 3800-3804 PR_EXT:000011471 denotes TrkC
T2296 3820-3825 CL_GO_EXT:cell denotes cells
T2297 3846-3850 UBERON:0000044 denotes DRGs
T2298 3854-3861 NCBITaxon:33208 denotes animals
T2299 3875-3884 SO_EXT:genotype_or_entity_with_genotype denotes genotypes
T2300 3907-3910 PR_EXT:000002193 denotes Bax
T2301 3911-3915 PR_EXT:000011459 denotes NT-3
T2302 3923-3927 SO_EXT:sequence_nullness denotes null
T2303 3928-3932 UBERON:0000044 denotes DRGs
T2304 3937-3941 PR_EXT:000011469 denotes TrkA
T2305 3942-3946 PR_EXT:000011471 denotes TrkC
T2306 3974-3977 PR_EXT:000002193 denotes Bax
T2307 3978-3982 SO_EXT:sequence_nullness denotes null
T2308 3983-3987 UBERON:0000044 denotes DRGs
T2309 4014-4018 PR_EXT:000011459 denotes NT-3
T2310 4019-4023 SO_EXT:sequence_nullness denotes null
T2311 4024-4028 UBERON:0000044 denotes DRGs
T2312 4042-4046 PR_EXT:000011471 denotes TrkC
T2313 4056-4063 CL:0000540 denotes neurons
T2314 4064-4071 SO_EXT:sequence_rescue_process denotes rescued
T2315 4075-4078 PR_EXT:000002193 denotes Bax
T2316 4079-4087 SO_EXT:sequence_deletion_entity_or_process denotes deletion
T2317 4108-4121 GO_RO_EXT:developmental_differentiation_process denotes differentiate
T2318 4160-4170 GO:0010467 denotes expression
T2319 4178-4192 GO:0019230 denotes proprioceptive
T2320 4193-4202 CHEBI_EXT:polyatomic_entity_or_group denotes molecular
T2321 4203-4209 CHEBI_SO_EXT:molecular_indicator_or_label_or_marker_or_tag denotes marker
T2322 4210-4221 PR_EXT:000013502 denotes Parvalbumin
T2323 4223-4225 PR_EXT:000013502 denotes PV
T3852 5055-5059 PR_EXT:000011459 denotes NT-3
T3853 5084-5095 GO_UBERON_EXT:innervation_entity_or_process denotes Innervation
T3854 5099-5104 GO_EXT:biological_movement_or_translocation_process denotes Motor
T3855 5099-5112 CL:0000100 denotes Motor Neurons
T3856 5113-5117 PR_EXT:000011469 denotes TrkA
T3857 5118-5122 PR_EXT:000011471 denotes TrkC
T3858 5146-5157 UBERON:0002240 denotes spinal cord
T3859 5196-5200 PR_EXT:000011469 denotes TrkA
T3860 5271-5282 UBERON:0002240 denotes spinal cord
T3861 5292-5296 PR_EXT:000011471 denotes TrkC
T3862 5325-5329 UBERON:0002240 denotes cord
T3863 5368-5381 UBERON:0002257 denotes ventral horns
T3864 5385-5387 SO_EXT:wild_type_entity_or_quality denotes WT
T3865 5416-5419 PR_EXT:000002193 denotes Bax
T3866 5423-5430 UBERON:0000922 denotes embryos
T3867 5456-5460 PR_EXT:000011471 denotes TrkC
T3868 5461-5471 GO:0010467 denotes expression
T3869 5475-5479 PR_EXT:000011459 denotes NT-3
T3870 5483-5494 UBERON:0002240 denotes spinal cord
T3871 5527-5541 GO:0019230 denotes proprioceptive
T3872 5563-5574 UBERON:0002240 denotes spinal cord
T3873 5576-5580 PR_EXT:000011471 denotes TrkC
T3874 5616-5627 UBERON:0002240 denotes spinal cord
T3875 5687-5689 SO_EXT:wild_type_entity_or_quality denotes WT
T3876 5693-5696 PR_EXT:000002193 denotes Bax
T3877 5746-5750 PR_EXT:000011471 denotes TrkC
T3878 5793-5801 GO_UBERON_EXT:nerve_ending_or_neuron_projection_terminus denotes terminal
T3879 5858-5872 _FRAGMENT denotes projections of
T3880 5877-5882 GO:0030424 denotes axons
T3881 5873-5876 UBERON:0000044 denotes DRG
T3882 5903-5909 CHEBI_EXT:35204 denotes tracer
T3883 5910-5913 CHEBI:52029 denotes DiI
T3884 5924-5926 SO_EXT:wild_type_entity_or_quality denotes WT
T3885 5931-5934 PR_EXT:000002193 denotes Bax
T3886 5938-5942 NCBITaxon_UBERON_EXT:pup denotes pups
T3887 5944-5958 GO:0019230 denotes proprioceptive
T3888 5988-5999 UBERON:0002240 denotes spinal cord
T3889 6041-6053 UBERON:0002257 denotes ventral horn
T3890 6090-6095 GO_EXT:biological_movement_or_translocation_process denotes motor
T3891 6090-6103 CL:0000100 denotes motor neurons
T3892 6111-6131 UBERON:0010405 denotes lateral motor column
T3893 6119-6124 GO_EXT:biological_movement_or_translocation_process denotes motor
T3894 6181-6184 CHEBI:52029 denotes DiI
T3895 6185-6193 CHEBI_SO_EXT:molecular_label_or_mark_or_tag_process denotes labeling
T3896 6217-6228 UBERON:0002240 denotes spinal cord
T3897 6232-6236 PR_EXT:000011459 denotes NT-3
T3898 6313-6327 GO:0019230 denotes proprioceptive
T3899 6328-6339 GO_UBERON_EXT:innervation_entity_or_process denotes innervation
T3900 6402-6416 GO:0019230 denotes proprioceptive
T3901 6478-6480 SO_EXT:wild_type_entity_or_quality denotes WT
T3902 6549-6561 UBERON:0000934 denotes ventral cord
T3903 6575-6595 UBERON:0010405 denotes lateral motor column
T3904 6583-6588 GO_EXT:biological_movement_or_translocation_process denotes motor
T3905 6630-6645 UBERON:0009571 denotes ventral midline
T3906 6664-6671 UBERON:0009571 denotes midline
T3907 6708-6720 UBERON:0000934 denotes ventral cord
T3908 6784-6788 PR_EXT:000011459 denotes NT-3
T3909 6806-6811 GO_EXT:biological_movement_or_translocation_process denotes motor
T3910 6806-6818 CL:0000100 denotes motor neuron
T3911 6819-6830 GO_UBERON_EXT:innervation_entity_or_process denotes innervation
T3912 6875-6878 CHEBI:52029 denotes DiI
T3913 6879-6887 CHEBI_SO_EXT:molecular_label_or_mark_or_tag_process denotes labeling
T3914 6896-6907 GO_UBERON_EXT:innervation_entity_or_process denotes Innervation
T3915 6924-6936 UBERON:0002240 denotes spinal cords
T3916 6988-7000 UBERON:0002256 denotes Dorsal horns
T3917 7008-7017 SO_EXT:genotype_or_entity_with_genotype denotes genotypes
T3918 7035-7038 CHEBI:52029 denotes DiI
T3919 7039-7046 CHEBI_SO_EXT:molecular_label_or_mark_or_tag_process denotes labeled
T3920 7071-7076 UBERON:0001021 denotes nerve
T3921 7071-7090 PR_EXT:000011194 denotes nerve growth factor
T3922 7077-7083 GO_EXT:biological_growth_entity_or_process denotes growth
T3923 7077-7090 GO_EXT:0008083 denotes growth factor
T3924 7101-7112 GO:0019233 denotes nociceptive
T3925 7113-7118 GO:0030424 denotes axons
T3926 7123-7125 SO_EXT:wild_type_entity_or_quality denotes WT
T3927 7130-7133 PR_EXT:000002193 denotes Bax
T3928 7137-7144 UBERON:0000922 denotes embryos
T3929 7146-7160 GO:0019230 denotes proprioceptive
T3930 7185-7197 UBERON:0002257 denotes ventral horn
T3931 7198-7203 GO_EXT:biological_movement_or_translocation_process denotes motor
T3932 7198-7211 CL:0000100 denotes motor neurons
T3933 7244-7257 UBERON:0002257 denotes ventral horns
T3934 7265-7269 PR_EXT:000011459 denotes NT-3
T3935 7273-7280 UBERON:0000922 denotes embryos
T3936 7296-7307 GO_UBERON_EXT:innervation_entity_or_process denotes innervation
T3937 7328-7331 PR_EXT:000002193 denotes Bax
T3938 7332-7336 PR_EXT:000011459 denotes NT-3
T3939 7349-7352 CHEBI:52029 denotes DiI
T3940 7353-7360 CHEBI_SO_EXT:molecular_label_or_mark_or_tag_process denotes labeled
T3941 7388-7399 UBERON:0002240 denotes spinal cord
T3942 7426-7433 UBERON:0009571 denotes midline
T3943 7449-7461 UBERON:0002257 denotes ventral horn
T3944 7560-7574 GO:0019230 denotes proprioceptive
T3945 7575-7586 GO_UBERON_EXT:innervation_entity_or_process denotes innervation
T3946 7594-7609 _FRAGMENT denotes ventral horn of
T3947 7628-7639 UBERON:0002257 denotes spinal cord
T3948 7614-7617 PR_EXT:000002193 denotes Bax
T3949 7618-7622 PR_EXT:000011459 denotes NT-3
T3950 7623-7627 SO_EXT:sequence_nullness denotes null
T3951 7697-7704 GO_EXT:detection_or_sensing_of_stimulus denotes sensory
T3952 7705-7710 GO:0030424 denotes axons
T3953 7723-7728 GO_EXT:biological_movement_or_translocation_process denotes motor
T3954 7723-7735 CL:0000100 denotes motor neuron
T3955 7736-7745 GO:0030425 denotes dendrites
T3956 7753-7765 UBERON:0002257 denotes ventral horn
T3957 7791-7797 GO:0060004 denotes reflex
T3958 7802-7809 UBERON:0024914 denotes circuit
T3959 7870-7877 GO_EXT:detection_or_sensing_of_stimulus denotes sensory
T3960 7878-7883 GO:0030424 denotes axons
T3961 7888-7893 GO_EXT:biological_movement_or_translocation_process denotes motor
T3962 7888-7901 CL:0000100 denotes motor neurons
T3963 7920-7924 PR_EXT:000011459 denotes NT-3
T3964 7952-7956 PR_EXT:000011459 denotes NT-3
T3966 7968-7982 GO:0007411 denotes axon targeting
T3967 8008-8015 GO_EXT:detection_or_sensing_of_stimulus denotes sensory
T3968 8016-8020 GO:0030424 denotes axon
T3965 7968-7972 GO:0030424 denotes axon
T13213 25616-25624 GO:0046903 denotes secreted
R64 T396 T395 _lexicallyChainedTo spinal cord,regions of
R788 T3880 T3879 _lexicallyChainedTo axons,projections of
R789 T3947 T3946 _lexicallyChainedTo spinal cord,ventral horn of
R1351 T5912 T5911 _lexicallyChainedTo lower leg,skin of
R2536 T13156 T13155 _lexicallyChainedTo axons,projections of
R2538 T13368 T13367 _lexicallyChainedTo of sensory axons,targeting
R2539 T13234 T13233 _lexicallyChainedTo spinal cord,ventral horns of
R2540 T13254 T13253 _lexicallyChainedTo spinal cord,regions of

craft-ca-core-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T5705 9306-9310 PR:000011459 denotes NT-3
T5706 9411-9418 NCBITaxon:33208 denotes animals
T5707 9436-9443 UBERON:0003718 denotes spindle
T5708 9463-9483 UBERON:0001388 denotes gastrocnemius muscle
T5709 9485-9500 UBERON:0003718 denotes Muscle spindles
T5710 9541-9544 PR:000002193 denotes Bax
T5711 9548-9555 NCBITaxon:33208 denotes animals
T5712 9611-9625 GO:0019230 denotes Proprioceptive
T5713 9646-9659 GO:0005883 denotes neurofilament
T5714 9646-9661 PR:000011120 denotes neurofilament-M
T5715 9663-9665 GO:0005883 denotes NF
T5716 9663-9667 PR:000011120 denotes NF-M
T5717 9669-9677 GO:0042571 denotes antibody
T5718 9764-9772 GO:0042571 denotes antibody
T5719 9890-9905 UBERON:0003718 denotes muscle spindles
T5720 9909-9913 PR:000011459 denotes NT-3
T5721 9917-9924 NCBITaxon:33208 denotes animals
T5722 9967-9970 PR:000002193 denotes Bax
T5723 9974-9981 NCBITaxon:33208 denotes animals
T5724 9991-9999 UBERON:0003718 denotes spindles
T5725 10013-10021 UBERON:0003718 denotes spindles
T5726 10050-10057 NCBITaxon:33208 denotes animals
T5727 10063-10073 GO:0010467 denotes expressing
T5728 10074-10078 PR:000011459 denotes NT-3
T5729 10124-10128 PR:000011459 denotes NT-3
T5730 10162-10177 UBERON:0003718 denotes muscle spindles
T5731 10199-10204 UBERON:0002101 denotes limbs
T5732 10239-10254 UBERON:0003718 denotes Muscle spindles
T5733 10278-10282 PR:000011471 denotes TrkC
T5734 10283-10291 GO:0042571 denotes antibody
T5735 10302-10305 PR:000002193 denotes Bax
T5736 10309-10316 NCBITaxon:33208 denotes animals
T5737 10329-10333 PR:000011459 denotes NT-3
T5738 10369-10373 PR:000011459 denotes NT-3
T5739 10388-10395 NCBITaxon:33208 denotes animals
T5740 10397-10399 GO:0005883 denotes NF
T5741 10397-10401 PR:000011120 denotes NF-M
T5742 10438-10445 UBERON:0005090 denotes muscles
T5743 10456-10463 UBERON:0005090 denotes muscles
T5744 10473-10480 NCBITaxon:33208 denotes animals
T5745 10511-10523 UBERON:0006134 denotes nerve fibers
T5746 10545-10549 PR:000011471 denotes TrkC
T5747 10575-10582 UBERON:0005090 denotes muscles
T5748 10604-10606 GO:0005883 denotes NF
T5749 10604-10608 PR:000011120 denotes NF-M
T5750 10644-10649 GO:0030424 denotes axons
T5751 10662-10677 UBERON:0003718 denotes muscle spindles
T5752 10740-10754 GO:0019230 denotes proprioceptive
T5753 10755-10760 GO:0030424 denotes axons
T5754 10823-10827 PR:000011459 denotes NT-3
T5755 10893-10907 UBERON:0003718 denotes muscle spindle
T5756 10944-10946 GO:0005883 denotes NF
T5757 10944-10948 PR:000011120 denotes NF-M
T5758 10975-10978 CHEBI:52029 denotes DiI
T5759 11027-11041 UBERON:0003718 denotes muscle spindle
T5760 11139-11147 UBERON:0003718 denotes spindles
T5761 11185-11188 PR:000002193 denotes Bax
T5762 11205-11209 PR:000011459 denotes NT-3
T5763 11213-11220 UBERON:0000922 denotes embryos
T5764 11234-11237 PR:000002193 denotes Bax
T5765 11238-11242 PR:000011459 denotes NT-3
T5766 11255-11262 UBERON:0005090 denotes muscles
T5767 11278-11286 UBERON:0003718 denotes spindles
T5768 11315-11322 UBERON:0003718 denotes spindle
T5769 11354-11357 UBERON:0000978 denotes leg
T5770 11364-11370 UBERON:0000922 denotes embryo
T5771 11416-11419 CHEBI:52029 denotes DiI
T5772 11483-11498 UBERON:0003718 denotes muscle spindles
T5773 11541-11544 PR:000002193 denotes Bax
T5774 11550-11557 UBERON:0005090 denotes muscles
T5775 11582-11586 PR:000011459 denotes NT-3
T5776 11600-11607 NCBITaxon:33208 denotes animals
T5777 11618-11621 CHEBI:52029 denotes DiI
T5778 11670-11677 UBERON:0005090 denotes muscles
T5779 11736-11751 UBERON:0003718 denotes muscle spindles
T5780 11770-11774 PR:000011469 denotes TrkA
T5781 11775-11779 PR:000011471 denotes TrkC
T5782 11780-11790 GO:0010467 denotes expression
T5783 11804-11816 UBERON:0001323 denotes tibial nerve
T5784 11854-11874 UBERON:0001388 denotes gastrocnemius muscle
T5785 11890-11897 _FRAGMENT denotes skin of
T5786 11902-11911 UBERON:0004264 denotes lower leg
T5787 11916-11920 PR:000011459 denotes NT-3
T5788 11926-11930 PR:000011469 denotes TrkA
T5789 11940-11945 GO:0030424 denotes axons
T5790 11967-11979 UBERON:0001323 denotes tibial nerve
T5791 11998-12002 PR:000011471 denotes TrkC
T5792 12012-12017 GO:0030424 denotes axons
T5793 12032-12036 PR:000011469 denotes TrkA
T5794 12042-12046 PR:000011471 denotes TrkC
T5795 12055-12060 GO:0030424 denotes axons
T5796 12085-12088 PR:000002193 denotes Bax
T5797 12107-12114 NCBITaxon:33208 denotes animals
T5798 12164-12178 GO:0019230 denotes proprioceptive
T5799 12179-12184 GO:0030424 denotes axons
T5800 12222-12239 UBERON:0001021 denotes peripheral nerves
T5801 12254-12263 GO:0060384 denotes innervate
T5802 12277-12284 UBERON:0005090 denotes muscles
T5803 12303-12307 PR:000011459 denotes NT-3
T7699 13565-13569 PR:000011459 denotes NT-3
T7700 13595-13598 UBERON:0000044 denotes DRG
T7701 13599-13604 GO:0030424 denotes Axons
T7702 13642-13646 PR:000011459 denotes NT-3
T7703 13685-13690 GO:0030424 denotes axons
T7704 13734-13748 GO:0019230 denotes Proprioceptive
T7705 13749-13754 GO:0030424 denotes axons
T7706 13758-13762 NCBITaxon:10088 denotes mice
T7707 13773-13784 UBERON:0002315 denotes gray matter
T7708 13792-13803 UBERON:0002240 denotes spinal cord
T7709 13842-13849 UBERON:0009571 denotes midline
T7710 13871-13884 CL:0000100 denotes motor neurons
T7711 13957-13960 UBERON:0000044 denotes DRG
T7712 13975-13979 PR:000011459 denotes NT-3
T7713 14048-14054 NCBITaxon:27592 denotes bovine
T7714 14055-14060 UBERON:0001977 denotes serum
T7715 14055-14068 PR:000003918 denotes serum albumin
T7716 14132-14135 UBERON:0000044 denotes DRG
T7717 14136-14141 GO:0030424 denotes axons
T7718 14180-14184 PR:000011459 denotes NT-3
T7719 14256-14271 GO:0050918 denotes chemoattraction
T7720 14431-14435 PR:000011459 denotes NT-3
T7721 14444-14447 PR:000002193 denotes Bax
T7722 14453-14460 UBERON:0000045 denotes ganglia
T7723 14480-14495 GO:0050918 denotes chemoattraction
T7724 14517-14521 PR:000011459 denotes NT-3
T7725 14545-14549 PR:000011471 denotes TrkC
T7726 14558-14564 PR:000001405 denotes p75NTR
T7727 14610-14613 UBERON:0000044 denotes DRG
T7728 14636-14642 PR:000001405 denotes p75NTR
T7729 14646-14650 NCBITaxon:10088 denotes mice
T7730 14661-14666 GO:0030424 denotes Axons
T7731 14676-14683 UBERON:0000045 denotes ganglia
T7732 14703-14718 GO:0050918 denotes chemoattraction
T7733 14731-14735 PR:000011459 denotes NT-3
T7734 14783-14787 PR:000011471 denotes TrkC
T7735 14798-14808 MOP:0000779 denotes conjugated
T7736 14812-14815 GO:0071735 denotes IgG
T7737 14834-14838 PR:000011471 denotes TrkC
T7738 14890-14894 PR:000011459 denotes NT-3
T7739 14950-14954 PR:000011471 denotes TrkC
T7740 14962-14977 GO:0050918 denotes chemoattraction
T7741 15055-15059 PR:000011459 denotes NT-3
T7742 15158-15162 UBERON:0000044 denotes DRGs
T7743 15217-15224 UBERON:0000045 denotes ganglia
T7744 15366-15371 GO:0030424 denotes axons
T7745 15437-15440 UBERON:0000044 denotes DRG
T7746 15441-15452 UBERON:0002240 denotes spinal cord
T7747 15476-15480 PR:000011459 denotes NT-3
T7748 15508-15515 UBERON:0009571 denotes midline
T7749 15523-15534 UBERON:0002240 denotes spinal cord
T7750 15555-15559 PR:000011459 denotes NT-3
T7751 15635-15638 CHEBI:52029 denotes DiI
T7752 15660-15664 UBERON:0000044 denotes DRGs
T7753 15703-15714 UBERON:0002240 denotes spinal cord
T7754 15738-15745 GO:0040007 denotes growing
T7755 15758-15762 PR:000011459 denotes NT-3
T7756 15925-15936 UBERON:0002240 denotes spinal cord
T7757 15989-16000 UBERON:0002315 denotes gray matter
T7758 16024-16029 GO:0030424 denotes axons
T7759 16093-16098 GO:0030424 denotes Axons
T7760 16123-16134 UBERON:0002315 denotes gray matter
T7761 16150-16161 UBERON:0002240 denotes spinal cord
T7762 16162-16166 GO:0040007 denotes grow
T7763 16179-16186 UBERON:0009571 denotes midline
T7764 16219-16223 PR:000011459 denotes NT-3
T7765 16240-16244 GO:0030424 denotes axon
T7766 16264-16268 PR:000011459 denotes NT-3
T7767 16292-16296 UBERON:0000044 denotes DRGs
T7768 16311-16322 UBERON:0002240 denotes spinal cord
T7769 16354-16365 UBERON:0002240 denotes spinal cord
T7770 16379-16383 PR:000011459 denotes NT-3
T7771 16440-16443 UBERON:0000044 denotes DRG
T7772 16444-16449 GO:0030424 denotes axons
T12561 18335-18339 PR:000011459 denotes NT-3
T12562 18389-18394 GO:0030424 denotes axons
T12563 18443-18452 UBERON:0000922 denotes embryonic
T12564 18453-18458 NCBITaxon:10088 denotes mouse
T12565 18459-18476 UBERON:0005868 denotes maxillary process
T12566 18480-18499 UBERON:0001675 denotes trigeminal ganglion
T12567 18500-18507 CL:0000540 denotes neurons
T12568 18555-18559 PR:000011459 denotes NT-3
T12569 18564-18569 UBERON:0000955 denotes brain
T12570 18564-18597 PR:000004716 denotes brain-derived neurotrophic factor
T12571 18599-18603 PR:000004716 denotes BDNF
T12572 18701-18706 GO:0030424 denotes axons
T12573 18710-18714 UBERON:0002101 denotes limb
T12574 18745-18749 GO:0040007 denotes grow
T12575 18758-18770 PR:000021998 denotes neurotrophin
T12576 18862-18874 PR:000021998 denotes neurotrophin
T12577 18893-18903 GO:0042571 denotes antibodies
T12578 18942-18946 GO:0030424 denotes axon
T12579 18966-18970 UBERON:0002101 denotes limb
T12580 18986-18990 NCBITaxon:10088 denotes mice
T12581 19003-19010 GO:0010467 denotes express
T12582 19011-19015 PR:000011459 denotes NT-3
T12583 19026-19032 PR:000011141 denotes nestin
T12584 19033-19041 SO:0000167 denotes promoter
T12585 19049-19071 UBERON:0001017 denotes central nervous system
T12586 19091-19105 GO:0019230 denotes proprioceptive
T12587 19189-19193 PR:000011459 denotes NT-3
T12588 19194-19204 GO:0010467 denotes expression
T12589 19212-19223 UBERON:0002240 denotes spinal cord
T12590 19298-19302 PR:000011459 denotes NT-3
T12591 19361-19374 UBERON:0002257 denotes ventral horns
T12592 19378-19392 GO:0019230 denotes proprioceptive
T12593 19440-19454 GO:0019230 denotes proprioceptive
T12594 19480-19487 NCBITaxon:9031 denotes chicken
T12595 19488-19495 UBERON:0000922 denotes embryos
T12596 19535-19539 PR:000011459 denotes NT-3
T12597 19540-19548 GO:0042571 denotes antibody
T12598 19558-19569 UBERON:0002240 denotes spinal cord
T12599 19684-19692 GO:0042571 denotes antibody
T12600 19709-19713 PR:000011459 denotes NT-3
T12601 19896-19901 GO:0030424 denotes axons
T12602 19948-19952 PR:000011459 denotes NT-3
T12603 19962-19972 GO:0010467 denotes expression
T12604 19976-19980 PR:000011459 denotes NT-3
T12605 20039-20051 PR:000021998 denotes neurotrophin
T12606 20060-20064 PR:000004716 denotes BDNF
T12607 20125-20130 GO:0030424 denotes axons
T12608 20131-20142 GO:0060384 denotes innervating
T12609 20143-20146 UBERON:0001690 denotes ear
T12610 20178-20182 SO:0000704 denotes gene
T12611 20213-20217 PR:000004716 denotes BDNF
T12612 20218-20228 GO:0010467 denotes expression
T12613 20247-20251 PR:000011459 denotes NT-3
T12614 20252-20260 SO:0000167 denotes promoter
T12615 20273-20278 GO:0030424 denotes axons
T12616 20315-20319 PR:000004716 denotes BDNF
T12617 20327-20334 UBERON:0001844 denotes cochlea
T12618 20349-20358 GO:0010467 denotes expressed
T12619 20359-20363 PR:000011459 denotes NT-3
T12620 20377-20387 GO:0060384 denotes innervated
T12621 20397-20402 GO:0030424 denotes axons
T12622 20412-20416 PR:000011459 denotes NT-3
T12623 20450-20460 NCBITaxon:10508 denotes adenovirus
T12624 20470-20480 GO:0010467 denotes expression
T12625 20496-20500 GO:0030424 denotes axon
T12626 20515-20527 GO:0031099 denotes regeneration
T12627 20621-20627 GO:0030424 denotes axonal
T12628 20642-20655 UBERON:0002707 denotes corticospinal
T12629 20656-20661 GO:0030424 denotes axons
T12630 20673-20678 UBERON:0007023 denotes adult
T12631 20679-20690 UBERON:0002240 denotes spinal cord
T12632 20731-20736 GO:0030424 denotes axons
T12633 20768-20775 UBERON:0009571 denotes midline
T12634 20788-20792 PR:000011459 denotes NT-3
T12635 20826-20837 UBERON:0002240 denotes spinal cord
T12636 20935-20939 PR:000011459 denotes NT-3
T12637 21008-21020 CL:0000100 denotes motor neuron
T12638 21048-21052 PR:000011459 denotes NT-3
T12639 21056-21063 NCBITaxon:33208 denotes animals
T12640 21072-21082 GO:0010467 denotes expressing
T12641 21083-21087 PR:000011459 denotes NT-3
T12642 21109-21116 UBERON:0005090 denotes muscles
T12643 21166-21170 PR:000011459 denotes NT-3
T12644 21204-21218 GO:0019230 denotes proprioceptive
T12645 21204-21226 CL:1001451 denotes proprioceptive neurons
T12646 21230-21234 PR:000011459 denotes NT-3
T12647 21238-21245 NCBITaxon:33208 denotes animals
T12648 21257-21263 GO:0030424 denotes axonal
T12649 21257-21275 GO:0007411 denotes axonal pathfinding
T12650 21283-21294 UBERON:0002240 denotes spinal cord
T12651 21327-21331 PR:000011459 denotes NT-3
T12652 21359-21371 UBERON:0002240 denotes spinal cords
T12653 21381-21388 NCBITaxon:33208 denotes animals
T12654 21427-21440 CL:0000100 denotes motor neurons
T12655 21468-21472 PR:000011459 denotes NT-3
T12656 21490-21501 UBERON:0002240 denotes spinal cord
T12657 21557-21561 PR:000011459 denotes NT-3
T12658 21580-21593 UBERON:0002257 denotes ventral horns
T12659 21603-21607 NCBITaxon:10088 denotes mice
T12660 21691-21694 PR:000002193 denotes Bax
T12661 21695-21699 PR:000011459 denotes NT-3
T12662 21710-21714 NCBITaxon:10088 denotes mice
T12663 21791-21805 GO:0019230 denotes proprioceptive
T12664 21879-21893 GO:0019230 denotes proprioceptive
T12665 21934-21945 UBERON:0002240 denotes spinal cord
T12666 22007-22009 PR:000013502 denotes PV
T12667 22029-22032 CHEBI:52029 denotes DiI
T12668 22049-22066 UBERON:0001021 denotes peripheral nerves
T12669 22082-22084 PR:000013502 denotes PV
T12670 22121-22124 PR:000002193 denotes Bax
T12671 22125-22129 PR:000011459 denotes NT-3
T12672 22174-22187 PR:000021998 denotes neurotrophins
T12673 22233-22247 GO:0019230 denotes proprioceptive
T12674 22248-22253 GO:0030424 denotes axons
T12675 22262-22264 PR:000013502 denotes PV
T12676 22279-22283 SO:0000704 denotes gene
T12677 22304-22309 UBERON:0001021 denotes nerve
T12678 22304-22323 PR:000011194 denotes nerve growth factor
T12679 22335-22340 GO:0030424 denotes axons
T12680 22406-22408 PR:000013502 denotes PV
T12681 22427-22430 PR:000002193 denotes Bax
T12682 22431-22435 PR:000011459 denotes NT-3
T12683 22475-22489 GO:0019230 denotes proprioceptive
T12684 22490-22495 GO:0030424 denotes axons
T12685 22560-22580 UBERON:0001388 denotes gastrocnemius muscle
T12686 22611-22621 GO:0010467 denotes expressing
T12687 22622-22626 PR:000011471 denotes TrkC
T12688 22638-22643 UBERON:0007023 denotes adult
T12689 22644-22647 NCBITaxon:10114 denotes rat
T12690 22648-22651 UBERON:0000044 denotes DRG
T12691 22782-22786 PR:000011471 denotes TrkC
T12692 22887-22896 GO:0010467 denotes expressed
T12693 22910-22915 GO:0030424 denotes axons
T12694 22966-22980 GO:0019230 denotes proprioceptive
T12695 22966-22988 CL:1001451 denotes proprioceptive neurons
T12696 23007-23011 PR:000011459 denotes NT-3
T12697 23015-23019 PR:000011471 denotes TrkC
T12698 23025-23029 NCBITaxon:10088 denotes mice
T12699 23045-23049 PR:000011471 denotes TrkC
T12700 23066-23078 UBERON:0001323 denotes tibial nerve
T12701 23097-23111 GO:0019230 denotes proprioceptive
T12702 23112-23117 GO:0030424 denotes axons
T12703 23206-23210 PR:000011459 denotes NT-3
T12704 23251-23258 UBERON:0003718 denotes spindle
T12705 23282-23296 GO:0019230 denotes proprioceptive
T12706 23297-23302 GO:0030424 denotes axons
T12707 23333-23336 CHEBI:52029 denotes DiI
T12708 23353-23356 UBERON:0000044 denotes DRG
T12709 23357-23362 GO:0030424 denotes axons
T12710 23370-23381 UBERON:0002240 denotes spinal cord
T12711 23437-23451 GO:0019230 denotes proprioceptive
T12712 23452-23457 GO:0030424 denotes axons
T12713 23483-23490 UBERON:0000957 denotes laminae
T12714 23511-23523 UBERON:0000934 denotes ventral cord
T12715 23547-23550 PR:000002193 denotes Bax
T12716 23551-23555 PR:000011459 denotes NT-3
T12718 23646-23651 GO:0030424 denotes axons
T12719 23673-23684 UBERON:0002240 denotes spinal cord
T12720 23771-23776 GO:0030424 denotes axons
T12721 23790-23806 GO:0043195 denotes terminal boutons
T12722 23909-23914 GO:0030424 denotes axons
T12723 23924-23939 UBERON:0009571 denotes ventral midline
T12724 23992-24008 GO:0043195 denotes terminal boutons
T12725 24138-24142 PR:000007223 denotes Er81
T12726 24147-24151 PR:000007227 denotes Pea3
T12727 24157-24166 GO:0010467 denotes expressed
T12728 24170-24173 UBERON:0000044 denotes DRG
T12729 24174-24181 CL:0000540 denotes neurons
T12730 24193-24206 CL:0000100 denotes motor neurons
T12731 24224-24237 CL:0000187 denotes muscle fibers
T12732 24262-24273 UBERON:0002240 denotes spinal cord
T12733 24277-24281 PR:000007223 denotes Er81
T12734 24285-24289 NCBITaxon:10088 denotes mice
T12735 24299-24313 _FRAGMENT denotes projections of
T12736 24329-24334 GO:0030424 denotes axons
T12737 24314-24328 GO:0019230 denotes proprioceptive
T12738 24368-24373 GO:0030424 denotes axons
T12739 24389-24401 UBERON:0000934 denotes ventral cord
T12740 24470-24473 PR:000002193 denotes Bax
T12741 24474-24478 PR:000011459 denotes NT-3
T12742 24489-24493 NCBITaxon:10088 denotes mice
T12743 24522-24526 PR:000007223 denotes Er81
T12744 24530-24534 NCBITaxon:10088 denotes mice
T12745 24563-24567 PR:000011459 denotes NT-3
T12746 24576-24580 PR:000007223 denotes Er81
T12747 24581-24591 GO:0010467 denotes expression
T12748 24595-24598 UBERON:0000044 denotes DRG
T12749 24650-24654 PR:000007223 denotes Er81
T12750 24660-24670 GO:0010467 denotes expression
T12751 24713-24717 PR:000011459 denotes NT-3
T12752 24725-24728 PR:000002193 denotes Bax
T12753 24729-24733 PR:000011459 denotes NT-3
T12754 24744-24748 NCBITaxon:10088 denotes mice
T12755 24807-24817 GO:0010467 denotes expression
T12756 24835-24839 NCBITaxon:10088 denotes mice
T12757 24903-24906 UBERON:0000044 denotes DRG
T12758 24913-24920 GO:0010467 denotes express
T12759 24946-24950 PR:000007223 denotes Er81
T12760 24966-24971 GO:0030424 denotes axons
T12761 24972-24976 GO:0040007 denotes grow
T12762 25015-25026 UBERON:0002240 denotes spinal cord
T12763 25030-25033 PR:000002193 denotes Bax
T12764 25034-25038 PR:000011459 denotes NT-3
T12765 25049-25053 NCBITaxon:10088 denotes mice
T12766 25078-25082 PR:000007223 denotes Er81
T12767 25086-25090 NCBITaxon:10088 denotes mice
T12768 25119-25133 GO:0019230 denotes proprioceptive
T12769 25134-25139 GO:0030424 denotes axons
T12770 25169-25180 UBERON:0002240 denotes spinal cord
T12771 25217-25222 GO:0030424 denotes axons
T12772 25259-25270 UBERON:0002240 denotes spinal cord
T12773 25298-25311 CL:0000100 denotes motor neurons
T12774 25394-25398 NCBITaxon:10088 denotes mice
T12775 25440-25453 CL:0000100 denotes motor neurons
T12776 25461-25473 UBERON:0000934 denotes ventral cord
T12777 25484-25488 NCBITaxon:10088 denotes mice
T12778 25489-25491 PR:000013502 denotes PV
T12779 25513-25518 GO:0030424 denotes axons
T12780 25526-25539 UBERON:0002257 denotes ventral horns
T12781 25571-25584 CL:0000100 denotes motor neurons
T12782 25605-25609 NCBITaxon:10088 denotes mice
T12783 25611-25615 PR:000011459 denotes NT-3
T12784 25616-25624 GO:0046903 denotes secreted
T12785 25659-25673 GO:0019230 denotes proprioceptive
T12786 25674-25679 GO:0030424 denotes axons
T12787 25693-25714 UBERON:0010405 denotes lateral motor columns
T12788 25759-25763 PR:000011459 denotes NT-3
T12789 25780-25789 GO:0010467 denotes expressed
T12790 25805-25816 UBERON:0002240 denotes spinal cord
T12791 25837-25850 CL:0000100 denotes motor neurons
T12792 25913-25917 NCBITaxon:10088 denotes mice
T12793 25919-25923 PR:000011459 denotes NT-3
T12794 25924-25934 GO:0010467 denotes expression
T12795 25950-25961 UBERON:0002240 denotes spinal cord
T12796 26023-26032 UBERON:0000922 denotes embryonic
T12797 26033-26037 NCBITaxon:10088 denotes mice
T12798 26047-26051 PR:000011459 denotes NT-3
T12799 26064-26080 _FRAGMENT denotes ventral horns of
T12800 26085-26096 UBERON:0002257 denotes spinal cord
T12801 26154-26163 GO:0010467 denotes expressed
T12802 26174-26187 CL:0000100 denotes motor neurons
T12803 26196-26201 UBERON:0007023 denotes adult
T12804 26202-26213 UBERON:0002240 denotes spinal cord
T12805 26221-26234 CL:0000100 denotes motor neurons
T12806 26235-26242 GO:0010467 denotes express
T12807 26258-26262 PR:000011459 denotes NT-3
T12808 26287-26291 CL:0000125 denotes glia
T12809 26298-26305 GO:0010467 denotes express
T12810 26424-26428 NCBITaxon:10088 denotes mice
T12811 26434-26438 PR:000011459 denotes NT-3
T12812 26444-26454 GO:0010467 denotes expression
T12813 26466-26476 _FRAGMENT denotes regions of
T12814 26481-26492 UBERON:0001948 denotes spinal cord
T12815 26538-26542 PR:000011459 denotes NT-3
T12816 26562-26566 GO:0030424 denotes axon
T12817 26562-26575 GO:0007411 denotes axon guidance
T12818 26579-26593 GO:0019230 denotes proprioceptive
T12819 26594-26599 GO:0030424 denotes axons
T12820 26607-26618 UBERON:0002240 denotes spinal cord
T12821 26664-26679 GO:0050918 denotes chemoattraction
T12822 26683-26686 UBERON:0000044 denotes DRG
T12823 26687-26694 CL:0000540 denotes neurons
T12824 26719-26723 PR:000011459 denotes NT-3
T12825 26754-26757 PR:000002193 denotes Bax
T12826 26770-26773 PR:000001405 denotes p75
T12827 26779-26782 UBERON:0000044 denotes DRG
T12828 26825-26838 PR:000021998 denotes neurotrophins
T12829 26857-26861 GO:0030424 denotes axon
T12830 26857-26870 GO:0007411 denotes axon guidance
T12831 26871-26880 CHEBI:36357 denotes molecules
T12832 26913-26917 GO:0030424 denotes axon
T12833 26930-26934 PR:000011459 denotes NT-3
T12834 27017-27021 PR:000011459 denotes NT-3
T12835 27047-27052 GO:0030424 denotes axons
T12836 27160-27165 GO:0030424 denotes axons
T12837 27243-27247 PR:000011459 denotes NT-3
T12838 27278-27283 GO:0030424 denotes axons
T12839 27309-27321 PR:000021998 denotes neurotrophin
T12840 27345-27351 GO:0030424 denotes axonal
T12841 27451-27459 GO:0045202 denotes synaptic
T12842 27468-27474 GO:0060004 denotes reflex
T12843 27489-27494 PR:000017442 denotes Wnt-3
T12844 27521-27525 GO:0030424 denotes axon
T12845 27553-27564 UBERON:0002240 denotes spinal cord
T12846 27596-27604 CHEBI:36357 denotes molecule
T12847 27606-27611 PR:000015235 denotes Slit2
T12848 27613-27622 GO:0010467 denotes expressed
T12849 27630-27637 UBERON:0009571 denotes midline
T12850 27645-27658 CL:0000100 denotes motor neurons
T12851 27701-27707 GO:0030424 denotes axonal
T12852 27780-27783 UBERON:0000044 denotes DRG
T12853 27784-27791 CL:0000540 denotes neurons
T12854 27792-27799 GO:0010467 denotes express
T12855 27841-27855 GO:0019230 denotes proprioceptive
T12856 27856-27861 GO:0030424 denotes axons
T12857 27934-27939 PR:000015235 denotes Slit2
T12858 27968-27972 PR:000011459 denotes NT-3
T12859 27984-27987 UBERON:0000044 denotes DRG
T12860 27988-27993 GO:0030424 denotes axons
T12861 28085-28095 UBERON:0001675 denotes trigeminal
T12862 28096-28101 GO:0030424 denotes axons
T12863 28109-28118 UBERON:0002298 denotes brainstem
T12864 28156-28161 PR:000015235 denotes Slit2
T12865 28210-28223 GO:0019230 denotes propioceptive
T12866 28224-28229 GO:0030424 denotes axons
T12867 28237-28249 UBERON:0000934 denotes ventral cord
T12868 28261-28268 UBERON:0009571 denotes midline
T12869 28315-28317 PR:000013502 denotes PV
T12870 28318-28328 GO:0010467 denotes expression
T12871 28332-28335 PR:000002193 denotes Bax
T12872 28336-28340 PR:000011459 denotes NT-3
T12873 28344-28348 NCBITaxon:10088 denotes mice
T12874 28363-28365 PR:000013502 denotes PV
T12875 28366-28376 GO:0010467 denotes expression
T12876 28409-28413 GO:0030424 denotes axon
T12877 28409-28423 GO:0007411 denotes axon targeting
T12878 28428-28442 UBERON:0003718 denotes muscle spindle
T12879 28541-28545 GO:0030424 denotes axon
T12880 28541-28557 GO:0007411 denotes axon pathfinding
T12881 28572-28580 GO:0045202 denotes synaptic
T12882 28581-28587 GO:0060004 denotes reflex
T12883 28598-28612 UBERON:0003718 denotes muscle spindle
T12884 28648-28650 PR:000013502 denotes PV
T12885 28654-28658 NCBITaxon:10088 denotes mice
T12886 28808-28814 GO:0030424 denotes axonal
T12887 28808-28824 GO:0007411 denotes axonal targeting
T12888 28836-28839 PR:000002193 denotes Bax
T12889 28840-28844 PR:000011459 denotes NT-3
T12890 28855-28859 NCBITaxon:10088 denotes mice
T12891 28892-28894 PR:000013502 denotes PV
T12892 28895-28905 GO:0010467 denotes expression
T12893 28909-28923 GO:0019230 denotes proprioceptive
T12894 28964-28968 PR:000011459 denotes NT-3
T12895 28991-28995 GO:0030424 denotes axon
T12896 28991-29004 GO:0007411 denotes axon guidance
T12897 29013-29027 GO:0019230 denotes proprioceptive
T12898 29028-29033 GO:0030424 denotes axons
T12899 29108-29112 GO:0030424 denotes axon
T12900 29108-29121 GO:0007411 denotes axon guidance
T12901 29150-29155 GO:0030424 denotes axons
T12902 29198-29202 PR:000011459 denotes NT-3
T12903 29223-29231 CHEBI:36357 denotes molecule
T12904 29253-29262 _FRAGMENT denotes targeting
T12905 29286-29302 GO:0097374 denotes of sensory axons
T12906 29297-29302 GO:0030424 denotes axons
T12907 29318-29329 UBERON:0002240 denotes spinal cord
T12908 29331-29335 PR:000011459 denotes NT-3
T12909 29378-29382 GO:0030424 denotes axon
T12910 29378-29391 GO:0007411 denotes axon guidance
T12911 29392-29401 CHEBI:36357 denotes molecules
T12912 29408-29418 GO:0065007 denotes regulating
T12913 29419-29429 GO:0010467 denotes expression
T12914 29454-29468 GO:0019230 denotes proprioceptive
T12915 29454-29475 CL:1001451 denotes proprioceptive neuron
T12916 29516-29520 GO:0030424 denotes axon
T12917 29516-29529 GO:0007411 denotes axon guidance
T16148 29597-29600 PR:000002193 denotes Bax
T16149 29694-29698 PR:000011459 denotes NT-3
T16150 29773-29780 NCBITaxon:33208 denotes animals
T16151 29818-29825 NCBITaxon:33208 denotes animals
T16152 29848-29853 SO:0000704 denotes genes
T16153 29890-29897 SO:0000112 denotes Primers
T16154 29911-29914 PR:000002193 denotes Bax
T16155 30033-30040 SO:0000112 denotes Primers
T16156 30054-30058 PR:000011459 denotes NT-3
T16157 30220-30223 PR:000002193 denotes Bax
T16158 30232-30236 PR:000011459 denotes NT-3
T16159 30289-30292 PR:000002193 denotes Bax
T16160 30293-30297 PR:000011459 denotes NT-3
T16161 30308-30312 NCBITaxon:10088 denotes mice
T16162 30360-30363 PR:000001405 denotes p75
T16163 30440-30444 UBERON:0002415 denotes tail
T16164 30461-30468 NCBITaxon:33208 denotes animals
T16165 30479-30486 SO:0000112 denotes primers
T16166 30573-30580 SO:0000112 denotes primers
T16167 30666-30669 PR:000001405 denotes p75
T16168 30682-30691 UBERON:0000922 denotes embryonic
T16169 30712-30716 UBERON:0010148 denotes plug
T16170 30872-30878 NCBITaxon:33208 denotes Animal
T16171 30988-30995 NCBITaxon:33208 denotes animals
T16815 30998-31002 PR:000011469 denotes TrkA
T16816 31003-31007 PR:000011471 denotes TrkC
T16817 31037-31048 UBERON:0002240 denotes spinal cord
T16818 31104-31112 CHEBI:60004 denotes cocktail
T16819 31116-31122 NCBITaxon:9986 denotes rabbit
T16820 31128-31132 PR:000011469 denotes TrkA
T16821 31137-31141 NCBITaxon:9925 denotes goat
T16822 31147-31151 PR:000011471 denotes TrkC
T16823 31152-31162 GO:0042571 denotes antibodies
T16824 31221-31229 CHEBI:60004 denotes cocktail
T16825 31233-31236 CHEBI:37987 denotes CY3
T16826 31237-31247 MOP:0000779 denotes conjugated
T16827 31248-31254 NCBITaxon:9793 denotes donkey
T16828 31260-31266 NCBITaxon:9986 denotes rabbit
T16829 31271-31275 CHEBI:37926 denotes FITC
T16830 31276-31286 MOP:0000779 denotes conjugated
T16831 31287-31293 NCBITaxon:9793 denotes donkey
T16832 31299-31303 NCBITaxon:9925 denotes goat
T16833 31304-31314 GO:0042571 denotes antibodies
T16834 31387-31398 CHEBI:9750 denotes TritonX-100
T16835 31414-31420 NCBITaxon:9793 denotes donkey
T16836 31421-31426 UBERON:0001977 denotes serum
T16837 31432-31434 PR:000013502 denotes PV
T16838 31495-31500 NCBITaxon:10088 denotes mouse
T16839 31506-31508 PR:000013502 denotes PV
T16840 31509-31517 GO:0042571 denotes antibody
T16841 31587-31598 CHEBI:31624 denotes fluorescein
T16842 31599-31604 NCBITaxon:10088 denotes mouse
T16843 31608-31613 NCBITaxon:10088 denotes mouse
T16844 31709-31713 PR:000011469 denotes TrkA
T16845 31719-31723 PR:000011471 denotes TrkC
T17303 31831-31845 UBERON:0003718 denotes Muscle spindle
T17304 31857-31877 UBERON:0001388 denotes Gastrocnemius muscle
T17305 31966-31969 UBERON:0000978 denotes leg
T17306 31986-32006 UBERON:0001388 denotes gastrocnemius muscle
T17307 32012-32024 UBERON:0001323 denotes tibial nerve
T17308 32101-32109 GO:0042571 denotes antibody
T17309 32150-32157 UBERON:0003718 denotes spindle
T17310 32197-32204 SO:0001060 denotes isoform
T17311 32229-32234 NCBITaxon:10088 denotes mouse
T17312 32238-32243 NCBITaxon:10088 denotes mouse
T17313 32280-32286 NCBITaxon:9986 denotes rabbit
T17314 32292-32294 GO:0005883 denotes NF
T17315 32292-32296 PR:000011120 denotes NF-M
T17316 32297-32305 GO:0042571 denotes antibody
T17317 32321-32324 CHEBI:37987 denotes CY3
T17318 32325-32335 MOP:0000779 denotes conjugated
T17319 32336-32340 NCBITaxon:9925 denotes goat
T17320 32346-32352 NCBITaxon:9986 denotes rabbit
T17321 32353-32361 GO:0042571 denotes antibody
T17322 32434-32437 CHEBI:52029 denotes DiI
T17323 32462-32466 UBERON:0000044 denotes DRGs
T17324 32474-32481 UBERON:0000922 denotes embryos
T17325 32524-32544 UBERON:0001388 denotes gastrocnemius muscle
T17745 32613-32616 CHEBI:52029 denotes DiI
T17746 32627-32639 UBERON:0002240 denotes Spinal cords
T17747 32668-32672 UBERON:0000044 denotes DRGs
T17748 32728-32741 CL:0000100 denotes motor neurons
T17749 32759-32825 CHEBI:52029 denotes 1,1′-dioctadecyl-3,3,3′,3′-tetramethylindocarbocyanine perchlorate
T17750 32827-32830 CHEBI:52029 denotes DiI
T17751 32898-32902 UBERON:0000044 denotes DRGs
T17752 32912-32924 UBERON:0002240 denotes spinal cords
T17753 33238-33242 CHEBI:9754 denotes Tris
T18427 33288-33291 UBERON:0000044 denotes DRG
T18428 33334-33337 PR:000002193 denotes Bax
T18429 33348-33351 PR:000001405 denotes p75
T18430 33357-33362 NCBITaxon:10088 denotes mouse
T18431 33363-33370 UBERON:0000922 denotes embryos
T18432 33406-33410 UBERON:0000044 denotes DRGs
T18433 33559-33570 CHEBI:15366 denotes acetic acid
T18434 33676-33684 UBERON:0000045 denotes ganglion
T18435 33916-33920 PR:000011459 denotes NT-3
T18436 34085-34097 PR:000021998 denotes neurotrophin
T18437 34194-34202 UBERON:0000045 denotes ganglion
T18438 34302-34307 UBERON:0001977 denotes Serum
T18439 34377-34380 UBERON:0000044 denotes DRG
T18440 34404-34409 UBERON:0001977 denotes serum
T18441 34457-34461 PR:000011471 denotes TrkC
T18442 34476-34491 CHEBI:52217 denotes Pharmaceuticals
T19088 34596-34608 UBERON:0002240 denotes Spinal cords
T19089 34623-34627 UBERON:0000044 denotes DRGs
T19090 34666-34671 NCBITaxon:10088 denotes mouse
T19091 34672-34679 UBERON:0000922 denotes embryos
T19092 34728-34734 UBERON:0000479 denotes Tissue
T19093 34767-34773 UBERON:0000479 denotes Tissue
T19094 34843-34847 PR:000011459 denotes NT-3
T19095 34954-34961 UBERON:0009571 denotes midline
T19096 34969-34980 UBERON:0002240 denotes spinal cord
T19097 35032-35037 UBERON:0001977 denotes serum
T19098 35126-35129 CHEBI:16526 denotes CO2
T19099 35211-35214 CHEBI:52029 denotes DiI
T19100 35236-35240 UBERON:0000044 denotes DRGs
T19101 35300-35303 CHEBI:37958 denotes dye
T329 27-31 PR:000011459 denotes NT-3
T330 35-49 GO:0019230 denotes Proprioceptive
T331 50-54 GO:0030424 denotes Axon
T332 50-63 GO:0007411 denotes Axon Guidance
T333 64-126 PR:000011459 denotes NT-3 and Proprioceptive Axon Guidance Abstract Neurotrophin-3
T334 128-132 PR:000011459 denotes NT-3
T335 150-164 GO:0019230 denotes proprioceptive
T336 150-171 CL:1001451 denotes proprioceptive neuron
T337 211-215 SO:0000704 denotes gene
T338 216-219 PR:000002193 denotes Bax
T339 223-227 PR:000011459 denotes NT-3
T340 237-241 NCBITaxon:10088 denotes mice
T341 256-263 CL:0000540 denotes neurons
T342 300-304 GO:0030424 denotes axon
T343 330-334 PR:000011459 denotes NT-3
T344 346-350 PR:000011471 denotes TrkC
T345 383-388 GO:0030424 denotes axons
T346 394-413 UBERON:0000044 denotes dorsal root ganglia
T347 500-509 GO:0060384 denotes innervate
T348 530-545 UBERON:0003718 denotes muscle spindles
T349 561-565 PR:000011471 denotes TrkC
T350 575-580 GO:0030424 denotes axons
T351 607-614 UBERON:0005090 denotes muscles
T352 627-641 GO:0019230 denotes proprioceptive
T353 642-647 GO:0030424 denotes axons
T354 666-676 _FRAGMENT denotes regions of
T355 681-692 UBERON:0001948 denotes spinal cord
T356 712-719 UBERON:0009571 denotes midline
T357 771-775 PR:000011459 denotes NT-3
T358 779-799 UBERON:0000044 denotes dorsal root ganglion
T359 800-805 GO:0030424 denotes axons
T360 845-849 PR:000011459 denotes NT-3
T361 875-879 GO:0030424 denotes axon
T362 875-888 GO:0007411 denotes axon guidance
T363 889-897 CHEBI:36357 denotes molecule
T1110 2042-2046 UBERON:0002101 denotes limb
T1107 1992-1997 UBERON:0001021 denotes nerve
T1108 2026-2033 NCBITaxon:9031 denotes chicken
T1109 2034-2040 UBERON:0000922 denotes embryo
T1083 1100-1114 PR:000011459 denotes Neurotrophin-3
T1084 1116-1120 PR:000011459 denotes NT-3
T1085 1166-1180 GO:0019230 denotes proprioceptive
T1086 1191-1204 CL:0000100 denotes motor neurons
T1087 1246-1250 NCBITaxon:10088 denotes Mice
T1088 1264-1268 PR:000011459 denotes NT-3
T1089 1300-1304 PR:000011471 denotes TrkC
T1090 1312-1316 PR:000011471 denotes TrkC
T1091 1326-1332 CL:0000540 denotes neuron
T1092 1363-1368 PR:000014365 denotes Runx3
T1093 1422-1437 UBERON:0003718 denotes muscle spindles
T1094 1451-1465 GO:0019230 denotes proprioceptive
T1095 1451-1473 CL:1001451 denotes proprioceptive neurons
T1096 1477-1496 UBERON:0000044 denotes dorsal root ganglia
T1097 1498-1502 UBERON:0000044 denotes DRGs
T1098 1513-1518 GO:0030424 denotes axons
T1099 1665-1669 PR:000011459 denotes NT-3
T1100 1673-1682 GO:0010467 denotes expressed
T1101 1698-1709 UBERON:0002240 denotes spinal cord
T1102 1729-1738 UBERON:0004347 denotes limb buds
T1103 1772-1787 UBERON:0003718 denotes muscle spindles
T1104 1888-1893 GO:0030424 denotes axons
T1105 1913-1921 CL:0002372 denotes myotubes
T1106 1935-1949 UBERON:0003718 denotes muscle spindle
T1111 2065-2069 PR:000011459 denotes NT-3
T1112 2070-2078 GO:0042571 denotes antibody
T1113 2095-2104 UBERON:0004347 denotes limb buds
T1114 2128-2132 PR:000011471 denotes TrkC
T1115 2142-2149 CL:0000540 denotes neurons
T1116 2179-2192 CL:0000100 denotes motor neurons
T1117 2224-2228 PR:000011459 denotes NT-3
T1118 2402-2410 GO:0045202 denotes synaptic
T1119 2411-2417 GO:0060004 denotes reflex
T1120 2453-2457 PR:000011459 denotes NT-3
T1121 2496-2501 GO:0030424 denotes axons
T2167 2573-2577 PR:000011471 denotes TrkC
T2168 2587-2590 UBERON:0000044 denotes DRG
T2169 2591-2598 CL:0000540 denotes Neurons
T2170 2614-2617 PR:000002193 denotes Bax
T2171 2618-2622 PR:000011459 denotes NT-3
T2172 2639-2643 NCBITaxon:10088 denotes Mice
T2173 2644-2648 NCBITaxon:10088 denotes Mice
T2174 2678-2681 PR:000002193 denotes Bax
T2175 2727-2740 PR:000021998 denotes neurotrophins
T2176 2761-2764 PR:000002193 denotes Bax
T2177 2775-2790 CL:0000101 denotes sensory neurons
T2178 2809-2822 PR:000021998 denotes neurotrophins
T2179 2909-2915 GO:0030424 denotes axonal
T2180 2933-2937 PR:000011459 denotes NT-3
T2181 2955-2958 PR:000002193 denotes Bax
T2182 2973-2977 NCBITaxon:10088 denotes mice
T2183 2988-2992 NCBITaxon:10088 denotes mice
T2184 3016-3020 PR:000011459 denotes NT-3
T2185 3025-3028 PR:000002193 denotes Bax
T2186 3029-3034 SO:0000704 denotes genes
T2187 3049-3063 GO:0019230 denotes proprioceptive
T2188 3064-3082 GO:0030424 denotes axonal projections
T2189 3088-3092 PR:000011459 denotes NT-3
T2191 3131-3136 GO:0007567 denotes birth
T2192 3176-3180 PR:000011469 denotes TrkA
T2193 3181-3185 PR:000011471 denotes TrkC
T2194 3291-3295 PR:000011471 denotes TrkC
T2195 3361-3365 PR:000011459 denotes NT-3
T2196 3373-3382 UBERON:0000922 denotes embryonic
T2197 3410-3413 UBERON:0000044 denotes DRG
T2198 3420-3430 GO:0010467 denotes expressing
T2199 3438-3442 PR:000011469 denotes TrkA
T2200 3446-3450 PR:000011471 denotes TrkC
T2201 3509-3512 PR:000002193 denotes Bax
T2202 3516-3523 NCBITaxon:33208 denotes animals
T2203 3546-3551 GO:0007567 denotes natal
T2204 3575-3584 GO:0010467 denotes expressed
T2205 3585-3589 PR:000011471 denotes TrkC
T2206 3598-3602 PR:000011459 denotes NT-3
T2207 3606-3613 NCBITaxon:33208 denotes animals
T2208 3621-3624 PR:000002193 denotes Bax
T2209 3629-3636 SO:0000704 denotes genetic
T2210 3667-3676 GO:0010467 denotes expressed
T2211 3677-3681 PR:000011469 denotes TrkA
T2212 3686-3690 PR:000011471 denotes TrkC
T2213 3791-3795 PR:000011469 denotes TrkA
T2214 3800-3804 PR:000011471 denotes TrkC
T2215 3846-3850 UBERON:0000044 denotes DRGs
T2216 3854-3861 NCBITaxon:33208 denotes animals
T2217 3907-3910 PR:000002193 denotes Bax
T2218 3911-3915 PR:000011459 denotes NT-3
T2219 3928-3932 UBERON:0000044 denotes DRGs
T2220 3937-3941 PR:000011469 denotes TrkA
T2221 3942-3946 PR:000011471 denotes TrkC
T2222 3974-3977 PR:000002193 denotes Bax
T2223 3983-3987 UBERON:0000044 denotes DRGs
T2224 4014-4018 PR:000011459 denotes NT-3
T2225 4024-4028 UBERON:0000044 denotes DRGs
T2226 4042-4046 PR:000011471 denotes TrkC
T2227 4056-4063 CL:0000540 denotes neurons
T2228 4075-4078 PR:000002193 denotes Bax
T2229 4160-4170 GO:0010467 denotes expression
T2230 4178-4192 GO:0019230 denotes proprioceptive
T2231 4210-4221 PR:000013502 denotes Parvalbumin
T2232 4223-4225 PR:000013502 denotes PV
T3849 7968-7972 GO:0030424 denotes axon
T3850 7968-7982 GO:0007411 denotes axon targeting
T3767 5055-5059 PR:000011459 denotes NT-3
T3768 5099-5112 CL:0000100 denotes Motor Neurons
T3769 5113-5117 PR:000011469 denotes TrkA
T3770 5118-5122 PR:000011471 denotes TrkC
T3771 5146-5157 UBERON:0002240 denotes spinal cord
T3772 5196-5200 PR:000011469 denotes TrkA
T3773 5271-5282 UBERON:0002240 denotes spinal cord
T3774 5292-5296 PR:000011471 denotes TrkC
T3775 5325-5329 UBERON:0002240 denotes cord
T3776 5368-5381 UBERON:0002257 denotes ventral horns
T3777 5416-5419 PR:000002193 denotes Bax
T3778 5423-5430 UBERON:0000922 denotes embryos
T3779 5456-5460 PR:000011471 denotes TrkC
T3780 5461-5471 GO:0010467 denotes expression
T3781 5475-5479 PR:000011459 denotes NT-3
T3782 5483-5494 UBERON:0002240 denotes spinal cord
T3783 5527-5541 GO:0019230 denotes proprioceptive
T3784 5563-5574 UBERON:0002240 denotes spinal cord
T3785 5576-5580 PR:000011471 denotes TrkC
T3786 5616-5627 UBERON:0002240 denotes spinal cord
T3787 5693-5696 PR:000002193 denotes Bax
T3788 5746-5750 PR:000011471 denotes TrkC
T3789 5858-5872 _FRAGMENT denotes projections of
T3790 5877-5882 GO:0030424 denotes axons
T3791 5873-5876 UBERON:0000044 denotes DRG
T3792 5903-5909 CHEBI:35204 denotes tracer
T3793 5910-5913 CHEBI:52029 denotes DiI
T3794 5931-5934 PR:000002193 denotes Bax
T3795 5944-5958 GO:0019230 denotes proprioceptive
T3796 5988-5999 UBERON:0002240 denotes spinal cord
T3797 6041-6053 UBERON:0002257 denotes ventral horn
T3798 6090-6103 CL:0000100 denotes motor neurons
T3799 6111-6131 UBERON:0010405 denotes lateral motor column
T3800 6181-6184 CHEBI:52029 denotes DiI
T3801 6217-6228 UBERON:0002240 denotes spinal cord
T3802 6232-6236 PR:000011459 denotes NT-3
T3803 6313-6327 GO:0019230 denotes proprioceptive
T3804 6402-6416 GO:0019230 denotes proprioceptive
T3805 6549-6561 UBERON:0000934 denotes ventral cord
T3806 6575-6595 UBERON:0010405 denotes lateral motor column
T3807 6630-6645 UBERON:0009571 denotes ventral midline
T3808 6664-6671 UBERON:0009571 denotes midline
T3809 6708-6720 UBERON:0000934 denotes ventral cord
T3810 6784-6788 PR:000011459 denotes NT-3
T3811 6806-6818 CL:0000100 denotes motor neuron
T3812 6875-6878 CHEBI:52029 denotes DiI
T3813 6924-6936 UBERON:0002240 denotes spinal cords
T3814 6988-7000 UBERON:0002256 denotes Dorsal horns
T3815 7035-7038 CHEBI:52029 denotes DiI
T3816 7071-7076 UBERON:0001021 denotes nerve
T3817 7071-7090 PR:000011194 denotes nerve growth factor
T3818 7101-7112 GO:0019233 denotes nociceptive
T3819 7113-7118 GO:0030424 denotes axons
T3820 7130-7133 PR:000002193 denotes Bax
T3821 7137-7144 UBERON:0000922 denotes embryos
T3822 7146-7160 GO:0019230 denotes proprioceptive
T3823 7185-7197 UBERON:0002257 denotes ventral horn
T3824 7198-7211 CL:0000100 denotes motor neurons
T3825 7244-7257 UBERON:0002257 denotes ventral horns
T3826 7265-7269 PR:000011459 denotes NT-3
T3827 7273-7280 UBERON:0000922 denotes embryos
T3828 7328-7331 PR:000002193 denotes Bax
T3829 7332-7336 PR:000011459 denotes NT-3
T3830 7349-7352 CHEBI:52029 denotes DiI
T3831 7388-7399 UBERON:0002240 denotes spinal cord
T3832 7426-7433 UBERON:0009571 denotes midline
T3833 7449-7461 UBERON:0002257 denotes ventral horn
T3834 7560-7574 GO:0019230 denotes proprioceptive
T3835 7594-7609 _FRAGMENT denotes ventral horn of
T3836 7628-7639 UBERON:0002257 denotes spinal cord
T3837 7614-7617 PR:000002193 denotes Bax
T3838 7618-7622 PR:000011459 denotes NT-3
T3839 7705-7710 GO:0030424 denotes axons
T3840 7723-7735 CL:0000100 denotes motor neuron
T3841 7736-7745 GO:0030425 denotes dendrites
T3842 7753-7765 UBERON:0002257 denotes ventral horn
T3843 7791-7797 GO:0060004 denotes reflex
T3844 7802-7809 UBERON:0024914 denotes circuit
T3845 7878-7883 GO:0030424 denotes axons
T3846 7888-7901 CL:0000100 denotes motor neurons
T3847 7920-7924 PR:000011459 denotes NT-3
T3848 7952-7956 PR:000011459 denotes NT-3
T3851 8016-8020 GO:0030424 denotes axon
T2190 3108-3112 GO:0016265 denotes died
T12717 23594-23597 CHEBI:52029 denotes DiI
R63 T355 T354 _lexicallyChainedTo spinal cord,regions of
R786 T3790 T3789 _lexicallyChainedTo axons,projections of
R787 T3836 T3835 _lexicallyChainedTo spinal cord,ventral horn of
R1350 T5786 T5785 _lexicallyChainedTo lower leg,skin of
R2533 T12736 T12735 _lexicallyChainedTo axons,projections of
R2534 T12800 T12799 _lexicallyChainedTo spinal cord,ventral horns of
R2535 T12905 T12904 _lexicallyChainedTo of sensory axons,targeting
R2537 T12814 T12813 _lexicallyChainedTo spinal cord,regions of

craft-sa-dev

Id Subject Object Predicate Lexical cue
T5932 9306-9308 NN denotes NT
T5933 9314-9322 VBN denotes Required
T5934 9308-9309 HYPH denotes -
T5935 9309-9310 CD denotes 3
T5936 9311-9313 VBZ denotes Is
T5937 9323-9326 IN denotes for
T5938 9327-9333 JJ denotes Proper
T5939 9345-9356 NN denotes Innervation
T5940 9334-9344 JJ denotes Peripheral
T5941 9356-9484 sentence denotes In order to study peripheral innervation in double KO animals, we investigated spindle development in the gastrocnemius muscle.
T5942 9357-9359 IN denotes In
T5943 9423-9435 VBD denotes investigated
T5944 9360-9365 NN denotes order
T5945 9366-9368 TO denotes to
T5946 9369-9374 VB denotes study
T5947 9375-9385 JJ denotes peripheral
T5948 9386-9397 NN denotes innervation
T5949 9398-9400 IN denotes in
T5950 9401-9407 JJ denotes double
T5951 9408-9410 NN denotes KO
T5952 9411-9418 NNS denotes animals
T5953 9418-9420 , denotes ,
T5954 9420-9422 PRP denotes we
T5955 9436-9443 NN denotes spindle
T5956 9444-9455 NN denotes development
T5957 9456-9458 IN denotes in
T5958 9459-9462 DT denotes the
T5959 9477-9483 NN denotes muscle
T5960 9463-9476 NN denotes gastrocnemius
T5961 9483-9484 . denotes .
T5962 9484-9610 sentence denotes Muscle spindles could be identified easily in P0 WT and Bax KO animals by their characteristic morphology (Figure 4A and 4B).
T5963 9485-9491 NN denotes Muscle
T5964 9492-9500 NNS denotes spindles
T5965 9510-9520 VBN denotes identified
T5966 9501-9506 MD denotes could
T5967 9507-9509 VB denotes be
T5968 9521-9527 RB denotes easily
T5969 9528-9530 IN denotes in
T5970 9531-9533 NN denotes P0
T5971 9548-9555 NNS denotes animals
T5972 9534-9536 NN denotes WT
T5973 9537-9540 CC denotes and
T5974 9541-9544 NN denotes Bax
T5975 9545-9547 NN denotes KO
T5976 9556-9558 IN denotes by
T5977 9559-9564 PRP$ denotes their
T5978 9580-9590 NN denotes morphology
T5979 9565-9579 JJ denotes characteristic
T5980 9591-9592 -LRB- denotes (
T5981 9599-9601 NN denotes 4A
T5982 9592-9598 NN denotes Figure
T5983 9602-9605 CC denotes and
T5984 9606-9608 NN denotes 4B
T5985 9608-9609 -RRB- denotes )
T5986 9609-9610 . denotes .
T5987 9610-9854 sentence denotes Proprioceptive fibers labeled with neurofilament-M (NF-M) antibody formed ring-like spiral endings wrapped around intrafusal bag fibers labeled with S46 antibody, specific for slow developmental myosin heavy chain protein (Miller et al. 1985).
T5988 9611-9625 JJ denotes Proprioceptive
T5989 9626-9632 NNS denotes fibers
T5990 9678-9684 VBD denotes formed
T5991 9633-9640 VBN denotes labeled
T5992 9641-9645 IN denotes with
T5993 9646-9659 NN denotes neurofilament
T5994 9660-9661 NN denotes M
T5995 9659-9660 HYPH denotes -
T5996 9669-9677 NN denotes antibody
T5997 9662-9663 -LRB- denotes (
T5998 9663-9665 NN denotes NF
T5999 9666-9667 NN denotes M
T6000 9665-9666 HYPH denotes -
T6001 9667-9668 -RRB- denotes )
T6002 9685-9689 NN denotes ring
T6003 9690-9694 JJ denotes like
T6004 9689-9690 HYPH denotes -
T6005 9702-9709 NNS denotes endings
T6006 9695-9701 JJ denotes spiral
T6007 9710-9717 VBN denotes wrapped
T6008 9718-9724 IN denotes around
T6009 9725-9735 JJ denotes intrafusal
T6010 9740-9746 NNS denotes fibers
T6011 9736-9739 NN denotes bag
T6012 9747-9754 VBN denotes labeled
T6013 9755-9759 IN denotes with
T6014 9760-9763 NN denotes S46
T6015 9764-9772 NN denotes antibody
T6016 9772-9774 , denotes ,
T6017 9774-9782 JJ denotes specific
T6018 9783-9786 IN denotes for
T6019 9787-9791 JJ denotes slow
T6020 9792-9805 JJ denotes developmental
T6021 9825-9832 NN denotes protein
T6022 9806-9812 NN denotes myosin
T6023 9813-9818 JJ denotes heavy
T6024 9819-9824 NN denotes chain
T6025 9833-9834 -LRB- denotes (
T6026 9834-9840 NNP denotes Miller
T6027 9841-9843 FW denotes et
T6028 9844-9847 FW denotes al.
T6029 9848-9852 CD denotes 1985
T6030 9852-9853 -RRB- denotes )
T6031 9853-9854 . denotes .
T6032 9854-9947 sentence denotes As reported earlier, there were no muscle spindles in NT-3 KO animals (Ernfors et al. 1994).
T6033 9855-9857 IN denotes As
T6034 9858-9866 VBN denotes reported
T6035 9882-9886 VBD denotes were
T6036 9867-9874 RBR denotes earlier
T6037 9874-9876 , denotes ,
T6038 9876-9881 EX denotes there
T6039 9887-9889 DT denotes no
T6040 9897-9905 NNS denotes spindles
T6041 9890-9896 NN denotes muscle
T6042 9906-9908 IN denotes in
T6043 9909-9911 NN denotes NT
T6044 9914-9916 NN denotes KO
T6045 9911-9912 HYPH denotes -
T6046 9912-9913 CD denotes 3
T6047 9917-9924 NNS denotes animals
T6048 9925-9926 -LRB- denotes (
T6049 9926-9933 NNP denotes Ernfors
T6050 9934-9936 FW denotes et
T6051 9937-9940 FW denotes al.
T6052 9941-9945 CD denotes 1994
T6053 9945-9946 -RRB- denotes )
T6054 9946-9947 . denotes .
T6055 9947-10114 sentence denotes On the other hand, Bax KO animals had more spindles than WT, and spindles were in clusters similar to animals over-expressing NT-3 in the muscle (Wright et al. 1997).
T6056 9948-9950 IN denotes On
T6057 9982-9985 VBD denotes had
T6058 9951-9954 DT denotes the
T6059 9961-9965 NN denotes hand
T6060 9955-9960 JJ denotes other
T6061 9965-9967 , denotes ,
T6062 9967-9970 NN denotes Bax
T6063 9971-9973 NN denotes KO
T6064 9974-9981 NNS denotes animals
T6065 9986-9990 JJR denotes more
T6066 9991-9999 NNS denotes spindles
T6067 10000-10004 IN denotes than
T6068 10005-10007 NN denotes WT
T6069 10007-10009 , denotes ,
T6070 10009-10012 CC denotes and
T6071 10013-10021 NNS denotes spindles
T6072 10022-10026 VBD denotes were
T6073 10027-10029 IN denotes in
T6074 10030-10038 NNS denotes clusters
T6075 10039-10046 JJ denotes similar
T6076 10047-10049 IN denotes to
T6077 10050-10057 NNS denotes animals
T6078 10058-10073 VBG denotes over-expressing
T6079 10074-10076 NN denotes NT
T6080 10076-10077 HYPH denotes -
T6081 10077-10078 CD denotes 3
T6082 10079-10081 IN denotes in
T6083 10082-10085 DT denotes the
T6084 10086-10092 NN denotes muscle
T6085 10093-10094 -LRB- denotes (
T6086 10094-10100 NNP denotes Wright
T6087 10101-10103 FW denotes et
T6088 10104-10107 FW denotes al.
T6089 10108-10112 CD denotes 1997
T6090 10112-10113 -RRB- denotes )
T6091 10113-10114 . denotes .
T6092 10114-10238 sentence denotes Although NT-3-dependent cells were rescued, no muscle spindles were detected in the limbs of double KOs (Figure 4A and 4B).
T6093 10115-10123 IN denotes Although
T6094 10150-10157 VBN denotes rescued
T6095 10124-10126 NN denotes NT
T6096 10129-10138 JJ denotes dependent
T6097 10126-10127 HYPH denotes -
T6098 10127-10128 CD denotes 3
T6099 10128-10129 HYPH denotes -
T6100 10139-10144 NNS denotes cells
T6101 10145-10149 VBD denotes were
T6102 10183-10191 VBN denotes detected
T6103 10157-10159 , denotes ,
T6104 10159-10161 DT denotes no
T6105 10169-10177 NNS denotes spindles
T6106 10162-10168 NN denotes muscle
T6107 10178-10182 VBD denotes were
T6108 10192-10194 IN denotes in
T6109 10195-10198 DT denotes the
T6110 10199-10204 NNS denotes limbs
T6111 10205-10207 IN denotes of
T6112 10208-10214 JJ denotes double
T6113 10215-10218 NNS denotes KOs
T6114 10219-10220 -LRB- denotes (
T6115 10227-10229 NN denotes 4A
T6116 10220-10226 NN denotes Figure
T6117 10230-10233 CC denotes and
T6118 10234-10236 NN denotes 4B
T6119 10236-10237 -RRB- denotes )
T6120 10237-10238 . denotes .
T6121 10238-10360 sentence denotes Muscle spindles could be observed with TrkC antibody in WT and Bax KO animals, but not in NT-3 or double KOs (Figure 4E).
T6122 10239-10245 NN denotes Muscle
T6123 10246-10254 NNS denotes spindles
T6124 10264-10272 VBN denotes observed
T6125 10255-10260 MD denotes could
T6126 10261-10263 VB denotes be
T6127 10273-10277 IN denotes with
T6128 10278-10282 NN denotes TrkC
T6129 10283-10291 NN denotes antibody
T6130 10292-10294 IN denotes in
T6131 10295-10297 NN denotes WT
T6132 10309-10316 NNS denotes animals
T6133 10298-10301 CC denotes and
T6134 10302-10305 NN denotes Bax
T6135 10306-10308 NN denotes KO
T6136 10316-10318 , denotes ,
T6137 10318-10321 CC denotes but
T6138 10322-10325 RB denotes not
T6139 10326-10328 IN denotes in
T6140 10329-10331 NN denotes NT
T6141 10344-10347 NNS denotes KOs
T6142 10331-10332 HYPH denotes -
T6143 10332-10333 CD denotes 3
T6144 10334-10336 CC denotes or
T6145 10337-10343 JJ denotes double
T6146 10348-10349 -LRB- denotes (
T6147 10356-10358 NN denotes 4E
T6148 10349-10355 NN denotes Figure
T6149 10358-10359 -RRB- denotes )
T6150 10359-10360 . denotes .
T6151 10360-10524 sentence denotes In both NT-3 and double KO animals, NF-M-labeled fibers could be detected in muscles, thus the muscles of these animals were not completely devoid of nerve fibers.
T6152 10361-10363 IN denotes In
T6153 10426-10434 VBN denotes detected
T6154 10364-10368 CC denotes both
T6155 10369-10371 NN denotes NT
T6156 10385-10387 NN denotes KO
T6157 10371-10372 HYPH denotes -
T6158 10372-10373 CD denotes 3
T6159 10374-10377 CC denotes and
T6160 10378-10384 JJ denotes double
T6161 10388-10395 NNS denotes animals
T6162 10395-10397 , denotes ,
T6163 10397-10399 NN denotes NF
T6164 10400-10401 NN denotes M
T6165 10399-10400 HYPH denotes -
T6166 10402-10409 VBN denotes labeled
T6167 10401-10402 HYPH denotes -
T6168 10410-10416 NNS denotes fibers
T6169 10417-10422 MD denotes could
T6170 10423-10425 VB denotes be
T6171 10481-10485 VBD denotes were
T6172 10435-10437 IN denotes in
T6173 10438-10445 NNS denotes muscles
T6174 10445-10447 , denotes ,
T6175 10447-10451 RB denotes thus
T6176 10452-10455 DT denotes the
T6177 10456-10463 NNS denotes muscles
T6178 10464-10466 IN denotes of
T6179 10467-10472 DT denotes these
T6180 10473-10480 NNS denotes animals
T6181 10486-10489 RB denotes not
T6182 10490-10500 RB denotes completely
T6183 10501-10507 JJ denotes devoid
T6184 10508-10510 IN denotes of
T6185 10511-10516 NN denotes nerve
T6186 10517-10523 NNS denotes fibers
T6187 10523-10524 . denotes .
T6188 10524-10650 sentence denotes Since there were no TrkC-positive fibers in these muscles, we think that these NF-M-labeled fibers correspond to motor axons.
T6189 10525-10530 IN denotes Since
T6190 10537-10541 VBD denotes were
T6191 10531-10536 EX denotes there
T6192 10587-10592 VBP denotes think
T6193 10542-10544 DT denotes no
T6194 10559-10565 NNS denotes fibers
T6195 10545-10549 NN denotes TrkC
T6196 10549-10550 HYPH denotes -
T6197 10550-10558 JJ denotes positive
T6198 10566-10568 IN denotes in
T6199 10569-10574 DT denotes these
T6200 10575-10582 NNS denotes muscles
T6201 10582-10584 , denotes ,
T6202 10584-10586 PRP denotes we
T6203 10593-10597 IN denotes that
T6204 10624-10634 VBP denotes correspond
T6205 10598-10603 DT denotes these
T6206 10617-10623 NNS denotes fibers
T6207 10604-10606 NN denotes NF
T6208 10607-10608 NN denotes M
T6209 10606-10607 HYPH denotes -
T6210 10609-10616 VBN denotes labeled
T6211 10608-10609 HYPH denotes -
T6212 10635-10637 IN denotes to
T6213 10638-10643 NN denotes motor
T6214 10644-10649 NNS denotes axons
T6215 10649-10650 . denotes .
T6216 10650-10828 sentence denotes Absence of muscle spindles might be due to a failure in initiation of differentiation by proprioceptive axons, or a failure of maturation and maintenance in the absence of NT-3.
T6217 10651-10658 NN denotes Absence
T6218 10684-10686 VB denotes be
T6219 10659-10661 IN denotes of
T6220 10662-10668 NN denotes muscle
T6221 10669-10677 NNS denotes spindles
T6222 10678-10683 MD denotes might
T6223 10687-10690 IN denotes due
T6224 10691-10693 IN denotes to
T6225 10694-10695 DT denotes a
T6226 10696-10703 NN denotes failure
T6227 10704-10706 IN denotes in
T6228 10707-10717 NN denotes initiation
T6229 10718-10720 IN denotes of
T6230 10721-10736 NN denotes differentiation
T6231 10737-10739 IN denotes by
T6232 10740-10754 JJ denotes proprioceptive
T6233 10755-10760 NNS denotes axons
T6234 10760-10762 , denotes ,
T6235 10762-10764 CC denotes or
T6236 10765-10766 DT denotes a
T6237 10767-10774 NN denotes failure
T6238 10775-10777 IN denotes of
T6239 10778-10788 NN denotes maturation
T6240 10789-10792 CC denotes and
T6241 10793-10804 NN denotes maintenance
T6242 10805-10807 IN denotes in
T6243 10808-10811 DT denotes the
T6244 10812-10819 NN denotes absence
T6245 10820-10822 IN denotes of
T6246 10823-10825 NN denotes NT
T6247 10825-10826 HYPH denotes -
T6248 10826-10827 CD denotes 3
T6249 10827-10828 . denotes .
T6250 10828-10988 sentence denotes To distinguish between these two possibilities, we investigated muscle spindle development at E15 and E17 with S46/NF-M immunostaining as well as DiI labeling.
T6251 10829-10831 TO denotes To
T6252 10832-10843 VB denotes distinguish
T6253 10880-10892 VBD denotes investigated
T6254 10844-10851 IN denotes between
T6255 10852-10857 DT denotes these
T6256 10862-10875 NNS denotes possibilities
T6257 10858-10861 CD denotes two
T6258 10875-10877 , denotes ,
T6259 10877-10879 PRP denotes we
T6260 10893-10899 NN denotes muscle
T6261 10900-10907 NN denotes spindle
T6262 10908-10919 NN denotes development
T6263 10920-10922 IN denotes at
T6264 10923-10926 NN denotes E15
T6265 10927-10930 CC denotes and
T6266 10931-10934 NN denotes E17
T6267 10935-10939 IN denotes with
T6268 10940-10943 NN denotes S46
T6269 10949-10963 NN denotes immunostaining
T6270 10943-10944 HYPH denotes /
T6271 10944-10946 NN denotes NF
T6272 10947-10948 NN denotes M
T6273 10946-10947 HYPH denotes -
T6274 10964-10966 RB denotes as
T6275 10972-10974 IN denotes as
T6276 10967-10971 RB denotes well
T6277 10975-10978 NN denotes DiI
T6278 10979-10987 NN denotes labeling
T6279 10987-10988 . denotes .
T6280 10988-11109 sentence denotes No structures with the characteristic muscle spindle shape could be detected in any of the genotypes at E15 (Figure S2).
T6281 10989-10991 DT denotes No
T6282 10992-11002 NNS denotes structures
T6283 11057-11065 VBN denotes detected
T6284 11003-11007 IN denotes with
T6285 11008-11011 DT denotes the
T6286 11042-11047 NN denotes shape
T6287 11012-11026 JJ denotes characteristic
T6288 11027-11033 NN denotes muscle
T6289 11034-11041 NN denotes spindle
T6290 11048-11053 MD denotes could
T6291 11054-11056 VB denotes be
T6292 11066-11068 IN denotes in
T6293 11069-11072 DT denotes any
T6294 11073-11075 IN denotes of
T6295 11076-11079 DT denotes the
T6296 11080-11089 NNS denotes genotypes
T6297 11090-11092 IN denotes at
T6298 11093-11096 NN denotes E15
T6299 11097-11098 -LRB- denotes (
T6300 11105-11107 NN denotes S2
T6301 11098-11104 NN denotes Figure
T6302 11107-11108 -RRB- denotes )
T6303 11108-11109 . denotes .
T6304 11109-11233 sentence denotes However, numerous developing spindles could be identified at E17 in WT and Bax KOs, but not in NT-3 KO embryos (Figure 4C).
T6305 11110-11117 RB denotes However
T6306 11157-11167 VBN denotes identified
T6307 11117-11119 , denotes ,
T6308 11119-11127 JJ denotes numerous
T6309 11139-11147 NNS denotes spindles
T6310 11128-11138 VBG denotes developing
T6311 11148-11153 MD denotes could
T6312 11154-11156 VB denotes be
T6313 11168-11170 IN denotes at
T6314 11171-11174 NN denotes E17
T6315 11175-11177 IN denotes in
T6316 11178-11180 NN denotes WT
T6317 11181-11184 CC denotes and
T6318 11185-11188 NN denotes Bax
T6319 11189-11192 NNS denotes KOs
T6320 11192-11194 , denotes ,
T6321 11194-11197 CC denotes but
T6322 11198-11201 RB denotes not
T6323 11202-11204 IN denotes in
T6324 11205-11207 NN denotes NT
T6325 11210-11212 NN denotes KO
T6326 11207-11208 HYPH denotes -
T6327 11208-11209 CD denotes 3
T6328 11213-11220 NNS denotes embryos
T6329 11221-11222 -LRB- denotes (
T6330 11229-11231 NN denotes 4C
T6331 11222-11228 NN denotes Figure
T6332 11231-11232 -RRB- denotes )
T6333 11232-11233 . denotes .
T6334 11233-11415 sentence denotes Bax/NT-3 double null muscles were devoid of spindles (Figure 4C), except for one spindle-like structure observed in one leg of an embryo (Figure 4C, inset, denoted by the asterisk).
T6335 11234-11237 NN denotes Bax
T6336 11250-11254 JJ denotes null
T6337 11237-11238 HYPH denotes /
T6338 11238-11240 NN denotes NT
T6339 11240-11241 HYPH denotes -
T6340 11241-11242 CD denotes 3
T6341 11243-11249 JJ denotes double
T6342 11255-11262 NNS denotes muscles
T6343 11263-11267 VBD denotes were
T6344 11268-11274 JJ denotes devoid
T6345 11275-11277 IN denotes of
T6346 11278-11286 NNS denotes spindles
T6347 11287-11288 -LRB- denotes (
T6348 11295-11297 NN denotes 4C
T6349 11288-11294 NN denotes Figure
T6350 11297-11298 -RRB- denotes )
T6351 11298-11300 , denotes ,
T6352 11300-11306 IN denotes except
T6353 11307-11310 IN denotes for
T6354 11311-11314 CD denotes one
T6355 11328-11337 NN denotes structure
T6356 11315-11322 NN denotes spindle
T6357 11323-11327 JJ denotes like
T6358 11322-11323 HYPH denotes -
T6359 11338-11346 VBN denotes observed
T6360 11347-11349 IN denotes in
T6361 11350-11353 CD denotes one
T6362 11354-11357 NN denotes leg
T6363 11358-11360 IN denotes of
T6364 11361-11363 DT denotes an
T6365 11364-11370 NN denotes embryo
T6366 11371-11372 -LRB- denotes (
T6367 11390-11397 VBN denotes denoted
T6368 11372-11378 NN denotes Figure
T6369 11379-11381 NN denotes 4C
T6370 11381-11383 , denotes ,
T6371 11383-11388 NN denotes inset
T6372 11388-11390 , denotes ,
T6373 11398-11400 IN denotes by
T6374 11401-11404 DT denotes the
T6375 11405-11413 NN denotes asterisk
T6376 11413-11414 -RRB- denotes )
T6377 11414-11415 . denotes .
T6378 11415-11608 sentence denotes DiI labeling through the DRGs at E17 yielded similar results, with muscle spindles identified in parallel sections in WT and Bax null muscles (Figure 4D), but not in NT-3 or double KO animals.
T6379 11416-11419 NN denotes DiI
T6380 11420-11428 NN denotes labeling
T6381 11453-11460 VBD denotes yielded
T6382 11429-11436 IN denotes through
T6445 11752-11912 sentence denotes We also examined TrkA/TrkC expression at P0 in the tibial nerve, which carries sensory fibers to the gastrocnemius muscle as well as the skin of the lower leg.
T6446 11753-11755 PRP denotes We
T6447 11761-11769 VBD denotes examined
T6383 11437-11440 DT denotes the
T6384 11441-11445 NNS denotes DRGs
T6385 11446-11448 IN denotes at
T6386 11449-11452 NN denotes E17
T6387 11461-11468 JJ denotes similar
T6388 11469-11476 NNS denotes results
T6389 11476-11478 , denotes ,
T6390 11478-11482 IN denotes with
T6391 11499-11509 VBN denotes identified
T6392 11483-11489 NN denotes muscle
T6393 11490-11498 NNS denotes spindles
T6394 11510-11512 IN denotes in
T6395 11513-11521 JJ denotes parallel
T6396 11522-11530 NNS denotes sections
T6397 11531-11533 IN denotes in
T6398 11534-11536 NN denotes WT
T6399 11550-11557 NNS denotes muscles
T6400 11537-11540 CC denotes and
T6401 11541-11544 NN denotes Bax
T6402 11545-11549 JJ denotes null
T6403 11558-11559 -LRB- denotes (
T6404 11566-11568 NN denotes 4D
T6405 11559-11565 NN denotes Figure
T6406 11568-11569 -RRB- denotes )
T6407 11569-11571 , denotes ,
T6408 11571-11574 CC denotes but
T6409 11575-11578 RB denotes not
T6410 11579-11581 IN denotes in
T6411 11582-11584 NN denotes NT
T6412 11597-11599 NN denotes KO
T6413 11584-11585 HYPH denotes -
T6414 11585-11586 CD denotes 3
T6415 11587-11589 CC denotes or
T6416 11590-11596 JJ denotes double
T6417 11600-11607 NNS denotes animals
T6418 11607-11608 . denotes .
T6419 11608-11752 sentence denotes Although DiI-labeled fibers could be detected in double null muscles, they never formed ring-like structures characteristic of muscle spindles.
T6420 11609-11617 IN denotes Although
T6421 11646-11654 VBN denotes detected
T6422 11618-11621 NN denotes DiI
T6423 11622-11629 VBN denotes labeled
T6424 11621-11622 HYPH denotes -
T6425 11630-11636 NNS denotes fibers
T6426 11637-11642 MD denotes could
T6427 11643-11645 VB denotes be
T6428 11690-11696 VBD denotes formed
T6429 11655-11657 IN denotes in
T6430 11658-11664 JJ denotes double
T6431 11665-11669 JJ denotes null
T6432 11670-11677 NNS denotes muscles
T6433 11677-11679 , denotes ,
T6434 11679-11683 PRP denotes they
T6435 11684-11689 RB denotes never
T6436 11697-11701 NN denotes ring
T6437 11702-11706 JJ denotes like
T6438 11701-11702 HYPH denotes -
T6439 11707-11717 NNS denotes structures
T6440 11718-11732 JJ denotes characteristic
T6441 11733-11735 IN denotes of
T6442 11736-11742 NN denotes muscle
T6443 11743-11751 NNS denotes spindles
T6444 11751-11752 . denotes .
T6448 11756-11760 RB denotes also
T6449 11770-11774 NN denotes TrkA
T6450 11775-11779 NN denotes TrkC
T6451 11774-11775 HYPH denotes /
T6452 11780-11790 NN denotes expression
T6453 11791-11793 IN denotes at
T6454 11794-11796 NN denotes P0
T6455 11797-11799 IN denotes in
T6456 11800-11803 DT denotes the
T6457 11811-11816 NN denotes nerve
T6458 11804-11810 JJ denotes tibial
T6459 11816-11818 , denotes ,
T6460 11818-11823 WDT denotes which
T6461 11824-11831 VBZ denotes carries
T6462 11832-11839 JJ denotes sensory
T6463 11840-11846 NNS denotes fibers
T6464 11847-11849 IN denotes to
T6465 11850-11853 DT denotes the
T6466 11868-11874 NN denotes muscle
T6467 11854-11867 NN denotes gastrocnemius
T6468 11875-11877 RB denotes as
T6469 11883-11885 IN denotes as
T6470 11878-11882 RB denotes well
T6471 11886-11889 DT denotes the
T6472 11890-11894 NN denotes skin
T6473 11895-11897 IN denotes of
T6474 11898-11901 DT denotes the
T6475 11908-11911 NN denotes leg
T6476 11902-11907 JJR denotes lower
T6477 11911-11912 . denotes .
T6478 11912-12127 sentence denotes In NT-3 KOs, TrkA-positive axons could be seen in the tibial nerve but there were no TrkC-positive axons; in contrast, TrkA- and TrkC-labeled axons are both present in WT, Bax KO, and double KO animals (Figure 4F).
T6479 11913-11915 IN denotes In
T6480 11955-11959 VBN denotes seen
T6481 11916-11918 NN denotes NT
T6482 11921-11924 NNS denotes KOs
T6483 11918-11919 HYPH denotes -
T6484 11919-11920 CD denotes 3
T6485 11924-11926 , denotes ,
T6486 11926-11930 NN denotes TrkA
T6487 11931-11939 JJ denotes positive
T6488 11930-11931 HYPH denotes -
T6489 11940-11945 NNS denotes axons
T6490 11946-11951 MD denotes could
T6491 11952-11954 VB denotes be
T6492 12061-12064 VBP denotes are
T6493 11960-11962 IN denotes in
T6494 11963-11966 DT denotes the
T6495 11974-11979 NN denotes nerve
T6496 11967-11973 JJ denotes tibial
T6497 11980-11983 CC denotes but
T6498 11984-11989 EX denotes there
T6499 11990-11994 VBD denotes were
T6500 11995-11997 DT denotes no
T6501 12012-12017 NNS denotes axons
T6502 11998-12002 NN denotes TrkC
T6503 12003-12011 JJ denotes positive
T6504 12002-12003 HYPH denotes -
T6505 12017-12018 : denotes ;
T6506 12019-12021 IN denotes in
T6507 12022-12030 NN denotes contrast
T6508 12030-12032 , denotes ,
T6509 12032-12036 NN denotes TrkA
T6510 12047-12054 VBN denotes labeled
T6511 12036-12037 HYPH denotes -
T6512 12038-12041 CC denotes and
T6513 12042-12046 NN denotes TrkC
T6514 12046-12047 HYPH denotes -
T6515 12055-12060 NNS denotes axons
T6516 12065-12069 RB denotes both
T6517 12070-12077 JJ denotes present
T6518 12078-12080 IN denotes in
T6519 12081-12083 NN denotes WT
T6520 12107-12114 NNS denotes animals
T6521 12083-12085 , denotes ,
T6522 12085-12088 NN denotes Bax
T6523 12089-12091 NN denotes KO
T6524 12091-12093 , denotes ,
T6525 12093-12096 CC denotes and
T6526 12097-12103 JJ denotes double
T6527 12104-12106 NN denotes KO
T6528 12115-12116 -LRB- denotes (
T6529 12123-12125 NN denotes 4F
T6530 12116-12122 NN denotes Figure
T6531 12125-12126 -RRB- denotes )
T6532 12126-12127 . denotes .
T6533 12127-12308 sentence denotes These results suggest that although proprioceptive axons follow proper trajectories in distal peripheral nerves, they fail to innervate their target muscles in the absence of NT-3.
T6534 12128-12133 DT denotes These
T6535 12134-12141 NNS denotes results
T6536 12142-12149 VBP denotes suggest
T6537 12150-12154 IN denotes that
T6538 12246-12250 VBP denotes fail
T6539 12155-12163 IN denotes although
T6540 12185-12191 VBP denotes follow
T6541 12164-12178 JJ denotes proprioceptive
T6542 12179-12184 NNS denotes axons
T6543 12192-12198 JJ denotes proper
T6544 12199-12211 NNS denotes trajectories
T6545 12212-12214 IN denotes in
T6546 12215-12221 JJ denotes distal
T6547 12233-12239 NNS denotes nerves
T6548 12222-12232 JJ denotes peripheral
T6549 12239-12241 , denotes ,
T6550 12241-12245 PRP denotes they
T6551 12251-12253 TO denotes to
T6552 12254-12263 VB denotes innervate
T6553 12264-12269 PRP$ denotes their
T6554 12277-12284 NNS denotes muscles
T6555 12270-12276 NN denotes target
T6556 12285-12287 IN denotes in
T6557 12288-12291 DT denotes the
T6558 12292-12299 NN denotes absence
T6559 12300-12302 IN denotes of
T6560 12303-12305 NN denotes NT
T6561 12305-12306 HYPH denotes -
T6562 12306-12307 CD denotes 3
T6563 12307-12308 . denotes .
T7869 13565-13567 NN denotes NT
T7870 13570-13572 VBZ denotes Is
T7871 13567-13568 HYPH denotes -
T7872 13568-13569 CD denotes 3
T7873 13573-13574 DT denotes a
T7874 13575-13590 NN denotes Chemoattractant
T7875 13591-13594 IN denotes for
T7876 13595-13598 NN denotes DRG
T7877 13599-13604 NNS denotes Axons
T7878 13605-13607 FW denotes In
T7879 13608-13613 FW denotes Vitro
T7880 13613-13733 sentence denotes To test the hypothesis that NT-3 acts as a chemoattractant for sensory axons, we performed a series of in vitro assays.
T7881 13614-13616 TO denotes To
T7882 13617-13621 VB denotes test
T7883 13695-13704 VBD denotes performed
T7884 13622-13625 DT denotes the
T7885 13626-13636 NN denotes hypothesis
T7886 13637-13641 IN denotes that
T7887 13647-13651 VBZ denotes acts
T7888 13642-13644 NN denotes NT
T7889 13644-13645 HYPH denotes -
T7890 13645-13646 CD denotes 3
T7891 13652-13654 IN denotes as
T7892 13655-13656 DT denotes a
T7893 13657-13672 NN denotes chemoattractant
T7894 13673-13676 IN denotes for
T7895 13677-13684 JJ denotes sensory
T7896 13685-13690 NNS denotes axons
T7897 13690-13692 , denotes ,
T7898 13692-13694 PRP denotes we
T7899 13705-13706 DT denotes a
T7900 13707-13713 NN denotes series
T7901 13714-13716 IN denotes of
T7902 13717-13719 FW denotes in
T7903 13720-13725 FW denotes vitro
T7904 13726-13732 NNS denotes assays
T7905 13732-13733 . denotes .
T7906 13733-13916 sentence denotes Proprioceptive axons in mice enter the gray matter in the spinal cord and advance ventrally parallel to the midline by E13 and reach the motor neurons by E15 (Ozaki and Snider 1994).
T7907 13734-13748 JJ denotes Proprioceptive
T7908 13749-13754 NNS denotes axons
T7909 13763-13768 VBP denotes enter
T7910 13755-13757 IN denotes in
T7911 13758-13762 NNS denotes mice
T7912 13769-13772 DT denotes the
T7913 13778-13784 NN denotes matter
T7914 13773-13777 JJ denotes gray
T7915 13785-13787 IN denotes in
T7916 13788-13791 DT denotes the
T7917 13799-13803 NN denotes cord
T7918 13792-13798 JJ denotes spinal
T7919 13804-13807 CC denotes and
T7920 13808-13815 VBP denotes advance
T7921 13816-13825 RB denotes ventrally
T7922 13826-13834 RB denotes parallel
T7923 13835-13837 IN denotes to
T7924 13838-13841 DT denotes the
T7925 13842-13849 NN denotes midline
T7926 13850-13852 IN denotes by
T7927 13853-13856 NN denotes E13
T7928 13857-13860 CC denotes and
T7929 13861-13866 VBP denotes reach
T7930 13867-13870 DT denotes the
T7931 13877-13884 NNS denotes neurons
T7932 13871-13876 NN denotes motor
T7933 13885-13887 IN denotes by
T7934 13888-13891 NN denotes E15
T7935 13892-13893 -LRB- denotes (
T7936 13893-13898 NNP denotes Ozaki
T7937 13899-13902 CC denotes and
T7938 13903-13909 NNP denotes Snider
T7939 13910-13914 CD denotes 1994
T7940 13914-13915 -RRB- denotes )
T7941 13915-13916 . denotes .
T7942 13916-14012 sentence denotes We co-cultured collagen-embedded E13 WT DRG explants with NT-3-soaked sepharose beads (n = 26).
T7943 13917-13919 PRP denotes We
T7944 13920-13931 VBD denotes co-cultured
T7945 13932-13940 NN denotes collagen
T7946 13941-13949 VBN denotes embedded
T7947 13940-13941 HYPH denotes -
T7948 13961-13969 NNS denotes explants
T7949 13950-13953 NN denotes E13
T7950 13954-13956 NN denotes WT
T7951 13957-13960 NN denotes DRG
T7952 13970-13974 IN denotes with
T7953 13975-13977 NN denotes NT
T7954 13980-13986 VBN denotes soaked
T7955 13977-13978 HYPH denotes -
T7956 13978-13979 CD denotes 3
T7957 13979-13980 HYPH denotes -
T7958 13997-14002 NNS denotes beads
T7959 13987-13996 NN denotes sepharose
T7960 14003-14004 -LRB- denotes (
T7961 14008-14010 CD denotes 26
T7962 14004-14005 NN denotes n
T7963 14006-14007 SYM denotes =
T7964 14010-14011 -RRB- denotes )
T7965 14011-14012 . denotes .
T7966 14012-14131 sentence denotes Control cultures were set up using bovine serum albumin (BSA)– or phosphate buffer saline (PBS)–soaked beads (n = 12).
T7967 14013-14020 NN denotes Control
T7968 14021-14029 NNS denotes cultures
T7969 14035-14038 VBN denotes set
T7970 14030-14034 VBD denotes were
T7971 14039-14041 RP denotes up
T7972 14042-14047 VBG denotes using
T7973 14048-14054 JJ denotes bovine
T7974 14061-14068 NN denotes albumin
T7975 14055-14060 NN denotes serum
T7976 14109-14115 VBN denotes soaked
T7977 14069-14070 -LRB- denotes (
T7978 14070-14073 NN denotes BSA
T7979 14073-14074 -RRB- denotes )
T7980 14074-14075 -LRB- denotes –
T7981 14076-14078 CC denotes or
T7982 14079-14088 NN denotes phosphate
T7983 14096-14102 NN denotes saline
T7984 14089-14095 NN denotes buffer
T7985 14103-14104 -LRB- denotes (
T7986 14104-14107 NN denotes PBS
T7987 14107-14108 -RRB- denotes )
T7988 14108-14109 -RRB- denotes –
T7989 14116-14121 NNS denotes beads
T7990 14122-14123 -LRB- denotes (
T7991 14127-14129 CD denotes 12
T7992 14123-14124 NN denotes n
T7993 14125-14126 SYM denotes =
T7994 14129-14130 -RRB- denotes )
T7995 14130-14131 . denotes .
T7996 14131-14379 sentence denotes DRG axons began extending towards the localized NT-3 source by the end of the first day and consistently displayed a strong chemoattraction by 3 d in vitro, whereas they did not show such preference for BSA-loaded control beads (Figure 5A and 5B).
T7997 14132-14135 NN denotes DRG
T7998 14136-14141 NNS denotes axons
T7999 14142-14147 VBD denotes began
T8000 14148-14157 VBG denotes extending
T8001 14158-14165 IN denotes towards
T8002 14166-14169 DT denotes the
T8003 14185-14191 NN denotes source
T8004 14170-14179 JJ denotes localized
T8005 14180-14182 NN denotes NT
T8006 14182-14183 HYPH denotes -
T8007 14183-14184 CD denotes 3
T8008 14192-14194 IN denotes by
T8009 14195-14198 DT denotes the
T8010 14199-14202 NN denotes end
T8011 14203-14205 IN denotes of
T8012 14206-14209 DT denotes the
T8013 14216-14219 NN denotes day
T8014 14210-14215 JJ denotes first
T8015 14220-14223 CC denotes and
T8016 14224-14236 RB denotes consistently
T8017 14237-14246 VBD denotes displayed
T8018 14247-14248 DT denotes a
T8019 14256-14271 NN denotes chemoattraction
T8020 14249-14255 JJ denotes strong
T8021 14272-14274 IN denotes by
T8022 14275-14276 CD denotes 3
T8023 14277-14278 NN denotes d
T8024 14279-14281 FW denotes in
T8025 14282-14287 FW denotes vitro
T8026 14287-14289 , denotes ,
T8027 14289-14296 IN denotes whereas
T8028 14310-14314 VB denotes show
T8029 14297-14301 PRP denotes they
T8030 14302-14305 VBD denotes did
T8031 14306-14309 RB denotes not
T8032 14315-14319 JJ denotes such
T8033 14320-14330 NN denotes preference
T8034 14331-14334 IN denotes for
T8035 14335-14338 NN denotes BSA
T8036 14339-14345 VBN denotes loaded
T8037 14338-14339 HYPH denotes -
T8038 14354-14359 NNS denotes beads
T8039 14346-14353 NN denotes control
T8040 14360-14361 -LRB- denotes (
T8041 14368-14370 NN denotes 5A
T8042 14361-14367 NN denotes Figure
T8043 14371-14374 CC denotes and
T8044 14375-14377 NN denotes 5B
T8045 14377-14378 -RRB- denotes )
T8046 14378-14379 . denotes .
T8047 14379-14516 sentence denotes This attraction was not due to survival support of NT-3 because Bax null ganglia displayed the same chemoattraction (Figure 5C; n = 16).
T8048 14380-14384 DT denotes This
T8049 14385-14395 NN denotes attraction
T8050 14396-14399 VBD denotes was
T8051 14400-14403 RB denotes not
T8052 14404-14407 IN denotes due
T8053 14408-14410 IN denotes to
T8054 14411-14419 NN denotes survival
T8055 14420-14427 NN denotes support
T8056 14428-14430 IN denotes of
T8057 14431-14433 NN denotes NT
T8058 14433-14434 HYPH denotes -
T8059 14434-14435 CD denotes 3
T8060 14436-14443 IN denotes because
T8061 14461-14470 VBD denotes displayed
T8062 14444-14447 NN denotes Bax
T8063 14448-14452 JJ denotes null
T8064 14453-14460 NNS denotes ganglia
T8065 14471-14474 DT denotes the
T8066 14480-14495 NN denotes chemoattraction
T8067 14475-14479 JJ denotes same
T8068 14496-14497 -LRB- denotes (
T8069 14504-14506 NN denotes 5C
T8070 14497-14503 NN denotes Figure
T8071 14506-14507 : denotes ;
T8072 14508-14509 NN denotes n
T8073 14512-14514 CD denotes 16
T8074 14510-14511 SYM denotes =
T8075 14514-14515 -RRB- denotes )
T8076 14515-14516 . denotes .
T8077 14516-14565 sentence denotes NT-3 may act through either TrkC, or the p75NTR.
T8078 14517-14519 NN denotes NT
T8079 14526-14529 VB denotes act
T8080 14519-14520 HYPH denotes -
T8081 14520-14521 CD denotes 3
T8082 14522-14525 MD denotes may
T8083 14530-14537 IN denotes through
T8084 14538-14544 CC denotes either
T8085 14545-14549 NN denotes TrkC
T8086 14549-14551 , denotes ,
T8087 14551-14553 CC denotes or
T8088 14554-14557 DT denotes the
T8089 14558-14564 NN denotes p75NTR
T8090 14564-14565 . denotes .
T8091 14565-14660 sentence denotes We repeated the co-culture experiments with DRG explants derived from p75NTR KO mice (n = 18).
T8092 14566-14568 PRP denotes We
T8093 14569-14577 VBD denotes repeated
T8094 14578-14581 DT denotes the
T8095 14593-14604 NNS denotes experiments
T8096 14582-14592 NN denotes co-culture
T8097 14605-14609 IN denotes with
T8098 14610-14613 NN denotes DRG
T8099 14614-14622 NNS denotes explants
T8100 14623-14630 VBN denotes derived
T8101 14631-14635 IN denotes from
T8102 14636-14642 NN denotes p75NTR
T8103 14643-14645 NN denotes KO
T8104 14646-14650 NNS denotes mice
T8105 14651-14652 -LRB- denotes (
T8106 14656-14658 CD denotes 18
T8107 14652-14653 NN denotes n
T8108 14654-14655 SYM denotes =
T8109 14658-14659 -RRB- denotes )
T8110 14659-14660 . denotes .
T8111 14660-14754 sentence denotes Axons of these ganglia also showed strong chemoattraction towards the NT-3 beads (Figure 5D).
T8112 14661-14666 NNS denotes Axons
T8113 14689-14695 VBD denotes showed
T8114 14667-14669 IN denotes of
T8115 14670-14675 DT denotes these
T8116 14676-14683 NNS denotes ganglia
T8117 14684-14688 RB denotes also
T8118 14696-14702 JJ denotes strong
T8119 14703-14718 NN denotes chemoattraction
T8120 14719-14726 IN denotes towards
T8121 14727-14730 DT denotes the
T8122 14736-14741 NNS denotes beads
T8123 14731-14733 NN denotes NT
T8124 14733-14734 HYPH denotes -
T8125 14734-14735 CD denotes 3
T8126 14742-14743 -LRB- denotes (
T8127 14750-14752 NN denotes 5D
T8128 14743-14749 NN denotes Figure
T8129 14752-14753 -RRB- denotes )
T8130 14753-14754 . denotes .
T8131 14754-14930 sentence denotes Finally, we used diffusible TrkC receptors conjugated to IgG constant regions (TrkC-Fc) added to the medium (n = 6) to deplete soluble NT-3 from the collagen gels (Figure 5E).
T8132 14755-14762 RB denotes Finally
T8133 14767-14771 VBD denotes used
T8134 14762-14764 , denotes ,
T8135 14764-14766 PRP denotes we
T8136 14772-14782 JJ denotes diffusible
T8137 14788-14797 NNS denotes receptors
T8138 14783-14787 NN denotes TrkC
T8139 14798-14808 VBN denotes conjugated
T8140 14809-14811 IN denotes to
T8141 14812-14815 NN denotes IgG
T8142 14825-14832 NNS denotes regions
T8143 14816-14824 NN denotes constant
T8144 14833-14834 -LRB- denotes (
T8145 14839-14841 NN denotes Fc
T8146 14834-14838 NN denotes TrkC
T8147 14838-14839 HYPH denotes -
T8148 14841-14842 -RRB- denotes )
T8149 14843-14848 VBN denotes added
T8150 14849-14851 IN denotes to
T8151 14852-14855 DT denotes the
T8152 14856-14862 NN denotes medium
T8153 14863-14864 -LRB- denotes (
T8154 14868-14869 CD denotes 6
T8155 14864-14865 NN denotes n
T8156 14866-14867 SYM denotes =
T8157 14869-14870 -RRB- denotes )
T8158 14871-14873 TO denotes to
T8159 14874-14881 VB denotes deplete
T8160 14882-14889 JJ denotes soluble
T8161 14890-14892 NN denotes NT
T8162 14892-14893 HYPH denotes -
T8163 14893-14894 CD denotes 3
T8164 14895-14899 IN denotes from
T8165 14900-14903 DT denotes the
T8166 14913-14917 NNS denotes gels
T8167 14904-14912 NN denotes collagen
T8168 14918-14919 -LRB- denotes (
T8169 14926-14928 NN denotes 5E
T8170 14919-14925 NN denotes Figure
T8171 14928-14929 -RRB- denotes )
T8172 14929-14930 . denotes .
T8173 14930-15060 sentence denotes In the presence of TrkC-Fc the chemoattraction was completely blocked, demonstrating that the effect we see is specific for NT-3.
T8174 14931-14933 IN denotes In
T8175 14993-15000 VBN denotes blocked
T8176 14934-14937 DT denotes the
T8177 14938-14946 NN denotes presence
T8178 14947-14949 IN denotes of
T8179 14950-14954 NN denotes TrkC
T8180 14955-14957 NN denotes Fc
T8181 14954-14955 HYPH denotes -
T8182 14958-14961 DT denotes the
T8183 14962-14977 NN denotes chemoattraction
T8184 14978-14981 VBD denotes was
T8185 14982-14992 RB denotes completely
T8186 15000-15002 , denotes ,
T8187 15002-15015 VBG denotes demonstrating
T8188 15016-15020 IN denotes that
T8189 15039-15041 VBZ denotes is
T8190 15021-15024 DT denotes the
T8191 15025-15031 NN denotes effect
T8192 15032-15034 PRP denotes we
T8193 15035-15038 VBP denotes see
T8194 15042-15050 JJ denotes specific
T8195 15051-15054 IN denotes for
T8196 15055-15057 NN denotes NT
T8197 15057-15058 HYPH denotes -
T8198 15058-15059 CD denotes 3
T8199 15059-15060 . denotes .
T8200 15060-15250 sentence denotes In order to investigate the active range of our beads, we have repeated the cultures with WT E13 DRGs by placing the beads at increasing distances from the ganglia (n = 4 each) (Figure 5F).
T8201 15061-15063 IN denotes In
T8202 15124-15132 VBN denotes repeated
T8203 15064-15069 NN denotes order
T8204 15070-15072 TO denotes to
T8205 15073-15084 VB denotes investigate
T8206 15085-15088 DT denotes the
T8207 15096-15101 NN denotes range
T8208 15089-15095 JJ denotes active
T8209 15102-15104 IN denotes of
T8210 15105-15108 PRP$ denotes our
T8211 15109-15114 NNS denotes beads
T8212 15114-15116 , denotes ,
T8213 15116-15118 PRP denotes we
T8214 15119-15123 VBP denotes have
T8215 15133-15136 DT denotes the
T8216 15137-15145 NNS denotes cultures
T8217 15146-15150 IN denotes with
T8218 15151-15153 NN denotes WT
T8219 15158-15162 NNS denotes DRGs
T8220 15154-15157 NN denotes E13
T8221 15163-15165 IN denotes by
T8222 15166-15173 VBG denotes placing
T8223 15174-15177 DT denotes the
T8224 15178-15183 NNS denotes beads
T8225 15184-15186 IN denotes at
T8226 15187-15197 VBG denotes increasing
T8227 15198-15207 NNS denotes distances
T8228 15208-15212 IN denotes from
T8229 15213-15216 DT denotes the
T8230 15217-15224 NNS denotes ganglia
T8231 15225-15226 -LRB- denotes (
T8232 15230-15231 CD denotes 4
T8233 15226-15227 NN denotes n
T8234 15228-15229 SYM denotes =
T8235 15232-15236 DT denotes each
T8236 15236-15237 -RRB- denotes )
T8237 15238-15239 -LRB- denotes (
T8238 15246-15248 NN denotes 5F
T8239 15239-15245 NN denotes Figure
T8240 15248-15249 -RRB- denotes )
T8241 15249-15250 . denotes .
T8242 15250-15416 sentence denotes There was still preferred growth towards the bead at 1,200μm, the longest distance studied, although the number of axons and the extent of growth were not as robust.
T8243 15251-15256 EX denotes There
T8244 15257-15260 VBD denotes was
T8245 15261-15266 RB denotes still
T8246 15267-15276 JJ denotes preferred
T8247 15277-15283 NN denotes growth
T8248 15284-15291 IN denotes towards
T8249 15292-15295 DT denotes the
T8250 15296-15300 NN denotes bead
T8251 15301-15303 IN denotes at
T8252 15304-15309 CD denotes 1,200
T8253 15309-15311 NN denotes μm
T8254 15311-15313 , denotes ,
T8255 15313-15316 DT denotes the
T8256 15325-15333 NN denotes distance
T8257 15317-15324 JJS denotes longest
T8258 15334-15341 VBN denotes studied
T8259 15341-15343 , denotes ,
T8260 15343-15351 IN denotes although
T8261 15397-15401 VBD denotes were
T8262 15352-15355 DT denotes the
T8263 15356-15362 NN denotes number
T8264 15363-15365 IN denotes of
T8265 15366-15371 NNS denotes axons
T8266 15372-15375 CC denotes and
T8267 15376-15379 DT denotes the
T8268 15380-15386 NN denotes extent
T8269 15387-15389 IN denotes of
T8270 15390-15396 NN denotes growth
T8271 15402-15405 RB denotes not
T8272 15406-15408 RB denotes as
T8273 15409-15415 JJ denotes robust
T8274 15415-15416 . denotes .
T8275 15416-15576 sentence denotes Next, we set up E13 DRG spinal cord explant cultures using NT-3-loaded beads placed at the midline at mid-spinal cord level as an ectopic NT-3 source (n = 15).
T8276 15417-15421 RB denotes Next
T8277 15426-15429 VBD denotes set
T8278 15421-15423 , denotes ,
T8279 15423-15425 PRP denotes we
T8280 15430-15432 RP denotes up
T8281 15433-15436 NN denotes E13
T8282 15461-15469 NNS denotes cultures
T8283 15437-15440 NN denotes DRG
T8284 15441-15447 JJ denotes spinal
T8285 15448-15452 NN denotes cord
T8286 15453-15460 NN denotes explant
T8287 15470-15475 VBG denotes using
T8288 15476-15478 NN denotes NT
T8289 15481-15487 VBN denotes loaded
T8290 15478-15479 HYPH denotes -
T8291 15479-15480 CD denotes 3
T8292 15480-15481 HYPH denotes -
T8293 15488-15493 NNS denotes beads
T8294 15494-15500 VBN denotes placed
T8295 15501-15503 IN denotes at
T8296 15504-15507 DT denotes the
T8297 15508-15515 NN denotes midline
T8298 15516-15518 IN denotes at
T8299 15519-15529 JJ denotes mid-spinal
T8300 15535-15540 NN denotes level
T8301 15530-15534 NN denotes cord
T8302 15541-15543 IN denotes as
T8303 15544-15546 DT denotes an
T8304 15560-15566 NN denotes source
T8305 15547-15554 JJ denotes ectopic
T8306 15555-15557 NN denotes NT
T8307 15557-15558 HYPH denotes -
T8308 15558-15559 CD denotes 3
T8309 15567-15568 -LRB- denotes (
T8310 15572-15574 CD denotes 15
T8311 15568-15569 NN denotes n
T8312 15570-15571 SYM denotes =
T8313 15574-15575 -RRB- denotes )
T8314 15575-15576 . denotes .
T8315 15576-15634 sentence denotes Control cultures were set using PBS-loaded beads (n = 6).
T8316 15577-15584 NN denotes Control
T8317 15585-15593 NNS denotes cultures
T8318 15599-15602 VBN denotes set
T8319 15594-15598 VBD denotes were
T8320 15603-15608 VBG denotes using
T8321 15609-15612 NN denotes PBS
T8322 15613-15619 VBN denotes loaded
T8323 15612-15613 HYPH denotes -
T8324 15620-15625 NNS denotes beads
T8325 15626-15627 -LRB- denotes (
T8326 15631-15632 CD denotes 6
T8327 15627-15628 NN denotes n
T8328 15629-15630 SYM denotes =
T8329 15632-15633 -RRB- denotes )
T8330 15633-15634 . denotes .
T8331 15634-15851 sentence denotes DiI labeling through the DRGs revealed numerous fibers entering the spinal cord at ectopic regions and growing towards the NT-3 beads (Figure 6A), surrounding the beads and forming bundles around them (Figure 6C–6E).
T8332 15635-15638 NN denotes DiI
T8333 15639-15647 NN denotes labeling
T8334 15665-15673 VBD denotes revealed
T8335 15648-15655 IN denotes through
T8336 15656-15659 DT denotes the
T8337 15660-15664 NNS denotes DRGs
T8338 15674-15682 JJ denotes numerous
T8339 15683-15689 NNS denotes fibers
T8340 15690-15698 VBG denotes entering
T8341 15699-15702 DT denotes the
T8342 15710-15714 NN denotes cord
T8343 15703-15709 JJ denotes spinal
T8344 15715-15717 IN denotes at
T8345 15718-15725 JJ denotes ectopic
T8346 15726-15733 NNS denotes regions
T8347 15734-15737 CC denotes and
T8348 15738-15745 VBG denotes growing
T8349 15746-15753 IN denotes towards
T8350 15754-15757 DT denotes the
T8351 15763-15768 NNS denotes beads
T8352 15758-15760 NN denotes NT
T8353 15760-15761 HYPH denotes -
T8354 15761-15762 CD denotes 3
T8355 15769-15770 -LRB- denotes (
T8356 15777-15779 NN denotes 6A
T8357 15770-15776 NN denotes Figure
T8358 15779-15780 -RRB- denotes )
T8359 15780-15782 , denotes ,
T8360 15782-15793 VBG denotes surrounding
T8361 15794-15797 DT denotes the
T8362 15798-15803 NNS denotes beads
T8363 15804-15807 CC denotes and
T8364 15808-15815 VBG denotes forming
T8365 15816-15823 NNS denotes bundles
T8366 15824-15830 IN denotes around
T8367 15831-15835 PRP denotes them
T8368 15836-15837 -LRB- denotes (
T8369 15844-15846 NN denotes 6C
T8370 15837-15843 NN denotes Figure
T8371 15846-15847 SYM denotes –
T8372 15847-15849 NN denotes 6E
T8373 15849-15850 -RRB- denotes )
T8374 15850-15851 . denotes .
T8375 15851-16020 sentence denotes In control cultures, all labeled fibers were directed towards the dorsal spinal cord and terminated there, where they normally enter the gray matter at E13 (Figure 6B).
T8376 15852-15854 IN denotes In
T8377 15897-15905 VBN denotes directed
T8378 15855-15862 NN denotes control
T8379 15863-15871 NNS denotes cultures
T8380 15871-15873 , denotes ,
T8381 15873-15876 DT denotes all
T8382 15885-15891 NNS denotes fibers
T8383 15877-15884 VBN denotes labeled
T8384 15892-15896 VBD denotes were
T8385 15906-15913 IN denotes towards
T8386 15914-15917 DT denotes the
T8387 15932-15936 NN denotes cord
T8388 15918-15924 JJ denotes dorsal
T8389 15925-15931 JJ denotes spinal
T8390 15937-15940 CC denotes and
T8391 15941-15951 VBN denotes terminated
T8392 15952-15957 RB denotes there
T8393 15957-15959 , denotes ,
T8394 15959-15964 WRB denotes where
T8395 15979-15984 VBP denotes enter
T8396 15965-15969 PRP denotes they
T8397 15970-15978 RB denotes normally
T8398 15985-15988 DT denotes the
T8399 15994-16000 NN denotes matter
T8400 15989-15993 JJ denotes gray
T8401 16001-16003 IN denotes at
T8402 16004-16007 NN denotes E13
T8403 16008-16009 -LRB- denotes (
T8404 16016-16018 NN denotes 6B
T8405 16009-16015 NN denotes Figure
T8406 16018-16019 -RRB- denotes )
T8407 16019-16020 . denotes .
T8408 16020-16092 sentence denotes No axons were observed around the PBS-loaded control beads (Figure 6F).
T8409 16021-16023 DT denotes No
T8410 16024-16029 NNS denotes axons
T8411 16035-16043 VBN denotes observed
T8412 16030-16034 VBD denotes were
T8413 16044-16050 IN denotes around
T8414 16051-16054 DT denotes the
T8415 16074-16079 NNS denotes beads
T8416 16055-16058 NN denotes PBS
T8417 16059-16065 VBN denotes loaded
T8418 16058-16059 HYPH denotes -
T8419 16066-16073 NN denotes control
T8420 16080-16081 -LRB- denotes (
T8421 16088-16090 NN denotes 6F
T8422 16081-16087 NN denotes Figure
T8423 16090-16091 -RRB- denotes )
T8424 16091-16092 . denotes .
T8425 16092-16378 sentence denotes Axons that normally enter the gray matter through dorsal spinal cord grow towards the midline when presented with a localized NT-3 source, and new axon growth towards the NT-3 bead is initiated from DRGs, entering the spinal cord at ectopic loci at lateral mid-spinal cord (Figure 6G).
T8426 16093-16098 NNS denotes Axons
T8427 16162-16166 VBP denotes grow
T8428 16099-16103 WDT denotes that
T8429 16113-16118 VBP denotes enter
T8430 16104-16112 RB denotes normally
T8431 16119-16122 DT denotes the
T8432 16128-16134 NN denotes matter
T8433 16123-16127 JJ denotes gray
T8434 16135-16142 IN denotes through
T8435 16143-16149 JJ denotes dorsal
T8436 16157-16161 NN denotes cord
T8437 16150-16156 JJ denotes spinal
T8438 16167-16174 IN denotes towards
T8439 16175-16178 DT denotes the
T8440 16179-16186 NN denotes midline
T8441 16187-16191 WRB denotes when
T8442 16192-16201 VBN denotes presented
T8443 16202-16206 IN denotes with
T8444 16207-16208 DT denotes a
T8445 16224-16230 NN denotes source
T8446 16209-16218 JJ denotes localized
T8447 16219-16221 NN denotes NT
T8448 16221-16222 HYPH denotes -
T8449 16222-16223 CD denotes 3
T8450 16230-16232 , denotes ,
T8451 16232-16235 CC denotes and
T8452 16236-16239 JJ denotes new
T8453 16245-16251 NN denotes growth
T8454 16240-16244 NN denotes axon
T8455 16277-16286 VBN denotes initiated
T8456 16252-16259 IN denotes towards
T8457 16260-16263 DT denotes the
T8458 16269-16273 NN denotes bead
T8459 16264-16266 NN denotes NT
T8460 16266-16267 HYPH denotes -
T8461 16267-16268 CD denotes 3
T8462 16274-16276 VBZ denotes is
T8463 16287-16291 IN denotes from
T8464 16292-16296 NNS denotes DRGs
T8465 16296-16298 , denotes ,
T8466 16298-16306 VBG denotes entering
T8467 16307-16310 DT denotes the
T8468 16318-16322 NN denotes cord
T8469 16311-16317 JJ denotes spinal
T8470 16323-16325 IN denotes at
T8471 16326-16333 JJ denotes ectopic
T8472 16334-16338 NNS denotes loci
T8473 16339-16341 IN denotes at
T8474 16342-16349 JJ denotes lateral
T8475 16361-16365 NN denotes cord
T8476 16350-16360 JJ denotes mid-spinal
T8477 16366-16367 -LRB- denotes (
T8478 16374-16376 NN denotes 6G
T8479 16367-16373 NN denotes Figure
T8480 16376-16377 -RRB- denotes )
T8481 16377-16378 . denotes .
T8482 16378-16450 sentence denotes NT-3 is therefore capable of acting as a chemoattractant for DRG axons.
T8483 16379-16381 NN denotes NT
T8484 16384-16386 VBZ denotes is
T8485 16381-16382 HYPH denotes -
T8486 16382-16383 CD denotes 3
T8487 16387-16396 RB denotes therefore
T8488 16397-16404 JJ denotes capable
T8489 16405-16407 IN denotes of
T8490 16408-16414 VBG denotes acting
T8491 16415-16417 IN denotes as
T8492 16418-16419 DT denotes a
T8493 16420-16435 NN denotes chemoattractant
T8494 16436-16439 IN denotes for
T8495 16440-16443 NN denotes DRG
T8496 16444-16449 NNS denotes axons
T8497 16449-16450 . denotes .
T14353 23395-23398 CC denotes and
T14354 23399-23402 CD denotes two
T14355 23403-23405 NN denotes P0
T14356 23406-23411 NNS denotes cases
T14357 23411-23413 , denotes ,
T14358 23413-23416 CC denotes and
T14359 23417-23423 VBP denotes report
T14360 23424-23428 IN denotes that
T14361 23458-23462 VBP denotes stop
T14362 23429-23436 JJ denotes central
T14363 23452-23457 NNS denotes axons
T14364 23437-23451 JJ denotes proprioceptive
T14365 23463-23465 IN denotes in
T14366 23466-23469 DT denotes the
T14367 23483-23490 NNS denotes laminae
T14368 23470-23482 JJ denotes intermediate
T14369 23490-23492 , denotes ,
T14370 23492-23497 RB denotes never
T14371 23498-23506 VBG denotes entering
T14372 23507-23510 DT denotes the
T14373 23519-23523 NN denotes cord
T14374 23511-23518 JJ denotes ventral
T14375 23523-23524 . denotes .
T14376 23524-23685 sentence denotes We have examined nine Bax/NT-3 double KO cases, and often incomplete DiI labeling gives the impression that there are no axons reaching the ventral spinal cord.
T14377 23525-23527 PRP denotes We
T14378 23533-23541 VBN denotes examined
T14379 23528-23532 VBP denotes have
T14380 23542-23546 CD denotes nine
T14381 23566-23571 NNS denotes cases
T14382 23547-23550 NN denotes Bax
T14383 23563-23565 NN denotes KO
T14384 23550-23551 HYPH denotes /
T14385 23551-23553 NN denotes NT
T14386 23553-23554 HYPH denotes -
T14387 23554-23555 CD denotes 3
T14388 23556-23562 JJ denotes double
T14389 23571-23573 , denotes ,
T14390 23573-23576 CC denotes and
T14391 23577-23582 RB denotes often
T14392 23607-23612 VBZ denotes gives
T14393 23583-23593 JJ denotes incomplete
T14394 23598-23606 NN denotes labeling
T14395 23594-23597 NN denotes DiI
T14396 23613-23616 DT denotes the
T14397 23617-23627 NN denotes impression
T14398 23628-23632 IN denotes that
T14399 23639-23642 VBP denotes are
T14400 23633-23638 EX denotes there
T14401 23643-23645 DT denotes no
T14402 23646-23651 NNS denotes axons
T14403 23652-23660 VBG denotes reaching
T14404 23661-23664 DT denotes the
T14405 23680-23684 NN denotes cord
T14406 23665-23672 JJ denotes ventral
T14407 23673-23679 JJ denotes spinal
T14408 23684-23685 . denotes .
T14409 23685-23839 sentence denotes We have also seen cases similar to theirs (n = 4), but at higher magnification these axons did not have terminal boutons and were not completely labeled.
T14410 23686-23688 PRP denotes We
T14411 23699-23703 VBN denotes seen
T14412 23689-23693 VBP denotes have
T14413 23694-23698 RB denotes also
T14414 23704-23709 NNS denotes cases
T14415 23710-23717 JJ denotes similar
T14416 23718-23720 IN denotes to
T14417 23721-23727 PRP denotes theirs
T14418 23728-23729 -LRB- denotes (
T14419 23733-23734 CD denotes 4
T14420 23729-23730 NN denotes n
T14421 23731-23732 SYM denotes =
T14422 23734-23735 -RRB- denotes )
T14423 23735-23737 , denotes ,
T14424 23737-23740 CC denotes but
T13384 18296-18306 RB denotes Relatively
T13385 18311-18318 NNS denotes studies
T13386 18307-18310 JJ denotes few
T13387 18324-18334 VBN denotes implicated
T13388 18319-18323 VBP denotes have
T13389 18335-18337 NN denotes NT
T13390 18337-18338 HYPH denotes -
T13391 18338-18339 CD denotes 3
T13392 18340-18342 IN denotes as
T13393 18343-18344 DT denotes a
T13394 18361-18366 NN denotes agent
T13395 18345-18360 JJ denotes chemoattractant
T13396 18367-18370 IN denotes for
T13397 18371-18378 JJ denotes sensory
T13398 18389-18394 NNS denotes axons
T13399 18379-18382 CC denotes and
T13400 18383-18388 NN denotes motor
T13401 18394-18395 . denotes .
T13402 18395-18628 sentence denotes Previously noted chemoattractant action of the embryonic mouse maxillary process on trigeminal ganglion neurons (Lumsden and Davies 1986) is now attributed to NT-3 and brain-derived neurotrophic factor (BDNF) (O'Connor et al. 1999).
T13403 18396-18406 RB denotes Previously
T13404 18407-18412 VBN denotes noted
T13405 18429-18435 NN denotes action
T13406 18413-18428 NN denotes chemoattractant
T13407 18541-18551 VBN denotes attributed
T13408 18436-18438 IN denotes of
T13409 18439-18442 DT denotes the
T13410 18469-18476 NN denotes process
T13411 18443-18452 JJ denotes embryonic
T13412 18453-18458 NN denotes mouse
T13413 18459-18468 JJ denotes maxillary
T13414 18477-18479 IN denotes on
T13415 18480-18490 JJ denotes trigeminal
T13416 18500-18507 NNS denotes neurons
T13417 18491-18499 NN denotes ganglion
T13418 18508-18509 -LRB- denotes (
T13419 18509-18516 NNP denotes Lumsden
T13420 18517-18520 CC denotes and
T13421 18521-18527 NNP denotes Davies
T13422 18528-18532 CD denotes 1986
T13423 18532-18533 -RRB- denotes )
T13424 18534-18536 VBZ denotes is
T13425 18537-18540 RB denotes now
T13426 18552-18554 IN denotes to
T13427 18555-18557 NN denotes NT
T13428 18557-18558 HYPH denotes -
T13429 18558-18559 CD denotes 3
T13430 18560-18563 CC denotes and
T13431 18564-18569 NN denotes brain
T13432 18570-18577 VBN denotes derived
T13433 18569-18570 HYPH denotes -
T13434 18591-18597 NN denotes factor
T13435 18578-18590 JJ denotes neurotrophic
T13436 18598-18599 -LRB- denotes (
T13437 18599-18603 NN denotes BDNF
T13438 18603-18604 -RRB- denotes )
T13439 18605-18606 -LRB- denotes (
T13440 18606-18614 NNP denotes O'Connor
T13441 18615-18617 FW denotes et
T13442 18618-18621 FW denotes al.
T13443 18622-18626 CD denotes 1999
T13444 18626-18627 -RRB- denotes )
T13445 18627-18628 . denotes .
T13446 18628-18831 sentence denotes Recently, Tucker et al. (2001) showed that developing sensory and motor axons in limb slice cultures preferentially grow towards neurotrophin-soaked beads instead of following their normal trajectories.
T13447 18629-18637 RB denotes Recently
T13448 18660-18666 VBD denotes showed
T13449 18637-18639 , denotes ,
T13450 18639-18645 NNP denotes Tucker
T13451 18646-18648 FW denotes et
T13452 18649-18652 FW denotes al.
T13453 18653-18654 -LRB- denotes (
T13454 18654-18658 CD denotes 2001
T13455 18658-18659 -RRB- denotes )
T13456 18667-18671 IN denotes that
T13457 18745-18749 VBP denotes grow
T13458 18672-18682 JJ denotes developing
T13459 18701-18706 NNS denotes axons
T13460 18683-18690 JJ denotes sensory
T13461 18691-18694 CC denotes and
T13462 18695-18700 JJ denotes motor
T13463 18707-18709 IN denotes in
T13464 18710-18714 NN denotes limb
T13465 18715-18720 NN denotes slice
T13466 18721-18729 NNS denotes cultures
T13467 18730-18744 RB denotes preferentially
T13468 18750-18757 IN denotes towards
T13469 18758-18770 NN denotes neurotrophin
T13470 18771-18777 VBN denotes soaked
T13471 18770-18771 HYPH denotes -
T13472 18778-18783 NNS denotes beads
T13473 18784-18791 RB denotes instead
T13474 18792-18794 IN denotes of
T13475 18795-18804 VBG denotes following
T13476 18805-18810 PRP$ denotes their
T13477 18818-18830 NNS denotes trajectories
T13478 18811-18817 JJ denotes normal
T13479 18830-18831 . denotes .
T13480 18831-18971 sentence denotes Conversely, beads soaked with neurotrophin function-blocking antibodies led to reduction of sensory and motor axon growth towards the limb.
T13481 18832-18842 RB denotes Conversely
T13482 18904-18907 VBD denotes led
T13483 18842-18844 , denotes ,
T13484 18844-18849 NNS denotes beads
T13485 18850-18856 VBN denotes soaked
T13486 18857-18861 IN denotes with
T13487 18862-18874 NN denotes neurotrophin
T13488 18893-18903 NNS denotes antibodies
T13489 18875-18883 NN denotes function
T13490 18884-18892 VBG denotes blocking
T13491 18883-18884 HYPH denotes -
T13492 18908-18910 IN denotes to
T13493 18911-18920 NN denotes reduction
T13494 18921-18923 IN denotes of
T13495 18924-18931 JJ denotes sensory
T13496 18947-18953 NN denotes growth
T13497 18932-18935 CC denotes and
T13498 18936-18941 JJ denotes motor
T13499 18942-18946 NN denotes axon
T13500 18954-18961 IN denotes towards
T13501 18962-18965 DT denotes the
T13502 18966-18970 NN denotes limb
T13503 18970-18971 . denotes .
T13504 18971-19248 sentence denotes In transgenic mice, which over-express NT-3 under the nestin promoter in the central nervous system, the course of the proprioceptive afferents are altered and directed towards the regions with high levels of ectopic NT-3 expression in the spinal cord (Ringstedt et al. 1997).
T13505 18972-18974 IN denotes In
T13506 19120-19127 VBN denotes altered
T13507 18975-18985 JJ denotes transgenic
T13508 18986-18990 NNS denotes mice
T13509 18990-18992 , denotes ,
T13510 18992-18997 WDT denotes which
T13511 18998-19010 VBP denotes over-express
T13512 19011-19013 NN denotes NT
T13513 19013-19014 HYPH denotes -
T13514 19014-19015 CD denotes 3
T13515 19016-19021 IN denotes under
T13516 19022-19025 DT denotes the
T13517 19033-19041 NN denotes promoter
T13518 19026-19032 NN denotes nestin
T13519 19042-19044 IN denotes in
T13520 19045-19048 DT denotes the
T13521 19065-19071 NN denotes system
T13522 19049-19056 JJ denotes central
T13523 19057-19064 JJ denotes nervous
T13524 19071-19073 , denotes ,
T13525 19073-19076 DT denotes the
T13526 19077-19083 NN denotes course
T13527 19084-19086 IN denotes of
T13528 19087-19090 DT denotes the
T13529 19106-19115 NNS denotes afferents
T13530 19091-19105 JJ denotes proprioceptive
T13531 19116-19119 VBP denotes are
T13532 19128-19131 CC denotes and
T13533 19132-19140 VBN denotes directed
T13534 19141-19148 IN denotes towards
T13535 19149-19152 DT denotes the
T13536 19153-19160 NNS denotes regions
T13537 19161-19165 IN denotes with
T13538 19166-19170 JJ denotes high
T13539 19171-19177 NNS denotes levels
T13540 19178-19180 IN denotes of
T13541 19181-19188 JJ denotes ectopic
T13542 19194-19204 NN denotes expression
T13543 19189-19191 NN denotes NT
T13544 19191-19192 HYPH denotes -
T13545 19192-19193 CD denotes 3
T13546 19205-19207 IN denotes in
T13547 19208-19211 DT denotes the
T13548 19219-19223 NN denotes cord
T13549 19212-19218 JJ denotes spinal
T13550 19224-19225 -LRB- denotes (
T13551 19225-19234 NNP denotes Ringstedt
T13552 19235-19237 FW denotes et
T13553 19238-19241 FW denotes al.
T13554 19242-19246 CD denotes 1997
T13555 19246-19247 -RRB- denotes )
T13556 19247-19248 . denotes .
T13557 19248-19403 sentence denotes Ringstedt et al. considered the possibility that NT-3 may play a chemoattractant role during the innervation of ventral horns by proprioceptive afferents.
T13558 19249-19258 NNP denotes Ringstedt
T13559 19266-19276 VBD denotes considered
T13560 19259-19261 FW denotes et
T13561 19262-19265 FW denotes al.
T13562 19277-19280 DT denotes the
T13563 19281-19292 NN denotes possibility
T13564 19293-19297 IN denotes that
T13565 19307-19311 VB denotes play
T13566 19298-19300 NN denotes NT
T13567 19300-19301 HYPH denotes -
T13568 19301-19302 CD denotes 3
T13569 19303-19306 MD denotes may
T13570 19312-19313 DT denotes a
T13571 19330-19334 NN denotes role
T13572 19314-19329 NN denotes chemoattractant
T13573 19335-19341 IN denotes during
T13574 19342-19345 DT denotes the
T13575 19346-19357 NN denotes innervation
T13576 19358-19360 IN denotes of
T13577 19361-19368 JJ denotes ventral
T13578 19369-19374 NNS denotes horns
T13579 19375-19377 IN denotes by
T13580 19378-19392 JJ denotes proprioceptive
T13581 19393-19402 NNS denotes afferents
T13582 19402-19403 . denotes .
T13583 19403-19629 sentence denotes However, earlier findings of normal proprioceptive afferent trajectories in chicken embryos despite injection of function-blocking NT-3 antibody into the spinal cord (Oakley et al. 1995) led them to discount this possibility.
T13584 19404-19411 RB denotes However
T13585 19591-19594 VBD denotes led
T13586 19411-19413 , denotes ,
T13587 19413-19420 JJR denotes earlier
T13588 19421-19429 NNS denotes findings
T13589 19430-19432 IN denotes of
T13590 19433-19439 JJ denotes normal
T13591 19464-19476 NNS denotes trajectories
T13592 19440-19454 JJ denotes proprioceptive
T13593 19455-19463 JJ denotes afferent
T13594 19477-19479 IN denotes in
T13595 19480-19487 NN denotes chicken
T13596 19488-19495 NNS denotes embryos
T13597 19496-19503 IN denotes despite
T13598 19504-19513 NN denotes injection
T13599 19514-19516 IN denotes of
T13600 19517-19525 NN denotes function
T13601 19526-19534 VBG denotes blocking
T13602 19525-19526 HYPH denotes -
T13603 19540-19548 NN denotes antibody
T13604 19535-19537 NN denotes NT
T13605 19537-19538 HYPH denotes -
T13606 19538-19539 CD denotes 3
T13607 19549-19553 IN denotes into
T13608 19554-19557 DT denotes the
T13609 19565-19569 NN denotes cord
T13610 19558-19564 JJ denotes spinal
T13611 19570-19571 -LRB- denotes (
T13612 19571-19577 NNP denotes Oakley
T13613 19578-19580 FW denotes et
T13614 19581-19584 FW denotes al.
T13615 19585-19589 CD denotes 1995
T13616 19589-19590 -RRB- denotes )
T13617 19595-19599 PRP denotes them
T13618 19600-19602 TO denotes to
T13619 19603-19611 VB denotes discount
T13620 19612-19616 DT denotes this
T13621 19617-19628 NN denotes possibility
T13622 19628-19629 . denotes .
T13623 19629-19838 sentence denotes In that study, though, assays on the effectiveness of antibody perturbation on NT-3-dependent cell survival showed that effectiveness was significant (approximately 90%) but not complete (Oakley et al. 1995).
T13624 19630-19632 IN denotes In
T13625 19738-19744 VBD denotes showed
T13626 19633-19637 DT denotes that
T13627 19638-19643 NN denotes study
T13628 19643-19645 , denotes ,
T13629 19645-19651 RB denotes though
T13630 19651-19653 , denotes ,
T13631 19653-19659 NNS denotes assays
T13632 19660-19662 IN denotes on
T13633 19663-19666 DT denotes the
T13634 19667-19680 NN denotes effectiveness
T13635 19681-19683 IN denotes of
T13636 19684-19692 NN denotes antibody
T13637 19693-19705 NN denotes perturbation
T13638 19706-19708 IN denotes on
T13639 19709-19711 NN denotes NT
T13640 19714-19723 JJ denotes dependent
T13641 19711-19712 HYPH denotes -
T13642 19712-19713 CD denotes 3
T13643 19713-19714 HYPH denotes -
T13644 19729-19737 NN denotes survival
T13645 19724-19728 NN denotes cell
T13646 19745-19749 IN denotes that
T13647 19764-19767 VBD denotes was
T13648 19750-19763 NN denotes effectiveness
T13649 19768-19779 JJ denotes significant
T13650 19780-19781 -LRB- denotes (
T13651 19797-19798 NN denotes %
T13652 19781-19794 RB denotes approximately
T13653 19795-19797 CD denotes 90
T13654 19798-19799 -RRB- denotes )
T13655 19800-19803 CC denotes but
T13656 19804-19807 RB denotes not
T13657 19808-19816 JJ denotes complete
T13658 19817-19818 -LRB- denotes (
T13659 19818-19824 NNP denotes Oakley
T13660 19825-19827 FW denotes et
T13661 19828-19831 FW denotes al.
T13662 19832-19836 CD denotes 1995
T13663 19836-19837 -RRB- denotes )
T13664 19837-19838 . denotes .
T13665 19838-20006 sentence denotes Ringstedt et al. (1997) argue that while central sensory axons may still navigate properly in the absence of NT-3, ectopic expression of NT-3 disrupts their targeting.
T13666 19839-19848 NNP denotes Ringstedt
T13667 19863-19868 VBP denotes argue
T13668 19849-19851 FW denotes et
T13669 19852-19855 FW denotes al.
T13670 19856-19857 -LRB- denotes (
T13671 19857-19861 CD denotes 1997
T13672 19861-19862 -RRB- denotes )
T13673 19869-19873 IN denotes that
T13674 19981-19989 VBZ denotes disrupts
T13675 19874-19879 IN denotes while
T13676 19912-19920 VB denotes navigate
T13677 19880-19887 JJ denotes central
T13678 19896-19901 NNS denotes axons
T13679 19888-19895 JJ denotes sensory
T13680 19902-19905 MD denotes may
T13681 19906-19911 RB denotes still
T13682 19921-19929 RB denotes properly
T13683 19930-19932 IN denotes in
T13684 19933-19936 DT denotes the
T13685 19937-19944 NN denotes absence
T13686 19945-19947 IN denotes of
T13687 19948-19950 NN denotes NT
T13688 19950-19951 HYPH denotes -
T13689 19951-19952 CD denotes 3
T13690 19952-19954 , denotes ,
T13691 19954-19961 JJ denotes ectopic
T13692 19962-19972 NN denotes expression
T13693 19973-19975 IN denotes of
T13694 19976-19978 NN denotes NT
T13695 19978-19979 HYPH denotes -
T13696 19979-19980 CD denotes 3
T13697 19990-19995 PRP$ denotes their
T13698 19996-20005 NN denotes targeting
T13699 20005-20006 . denotes .
T13700 20006-20172 sentence denotes Recently, another member of the neurotrophin family, BDNF, has been suggested to act as a chemoattractant for sensory axons innervating ear (Tessarollo et al. 2004).
T13701 20007-20015 RB denotes Recently
T13702 20075-20084 VBN denotes suggested
T13703 20015-20017 , denotes ,
T13704 20017-20024 DT denotes another
T13705 20025-20031 NN denotes member
T13706 20032-20034 IN denotes of
T13707 20035-20038 DT denotes the
T13708 20052-20058 NN denotes family
T13709 20039-20051 NN denotes neurotrophin
T13710 20058-20060 , denotes ,
T13711 20060-20064 NN denotes BDNF
T13712 20064-20066 , denotes ,
T13713 20066-20069 VBZ denotes has
T13714 20070-20074 VBN denotes been
T13715 20085-20087 TO denotes to
T13716 20088-20091 VB denotes act
T13717 20092-20094 IN denotes as
T13718 20095-20096 DT denotes a
T13719 20097-20112 NN denotes chemoattractant
T13720 20113-20116 IN denotes for
T13721 20117-20124 JJ denotes sensory
T13722 20125-20130 NNS denotes axons
T13723 20143-20146 NN denotes ear
T13724 20131-20142 VBG denotes innervating
T13725 20147-20148 -LRB- denotes (
T13726 20148-20158 NNP denotes Tessarollo
T13727 20159-20161 FW denotes et
T13728 20162-20165 FW denotes al.
T13729 20166-20170 CD denotes 2004
T13730 20170-20171 -RRB- denotes )
T13731 20171-20172 . denotes .
T13732 20172-20403 sentence denotes In a gene replacement strategy in which BDNF expression was driven by the NT-3 promoter, vestibular axons rerouted towards ectopic sources of BDNF in the cochlea that normally expressed NT-3 and were not innervated by these axons.
T13733 20173-20175 IN denotes In
T13734 20279-20287 VBP denotes rerouted
T13735 20176-20177 DT denotes a
T13736 20195-20203 NN denotes strategy
T13737 20178-20182 NN denotes gene
T13738 20183-20194 NN denotes replacement
T13739 20204-20206 IN denotes in
T13740 20233-20239 VBN denotes driven
T13741 20207-20212 WDT denotes which
T13742 20213-20217 NN denotes BDNF
T13743 20218-20228 NN denotes expression
T13744 20229-20232 VBD denotes was
T13745 20240-20242 IN denotes by
T13746 20243-20246 DT denotes the
T13747 20252-20260 NN denotes promoter
T13748 20247-20249 NN denotes NT
T13749 20249-20250 HYPH denotes -
T13750 20250-20251 CD denotes 3
T13751 20260-20262 , denotes ,
T13752 20262-20272 JJ denotes vestibular
T13753 20273-20278 NNS denotes axons
T13754 20288-20295 IN denotes towards
T13755 20296-20303 JJ denotes ectopic
T13756 20304-20311 NNS denotes sources
T13757 20312-20314 IN denotes of
T13758 20315-20319 NN denotes BDNF
T13759 20320-20322 IN denotes in
T13760 20323-20326 DT denotes the
T13761 20327-20334 NN denotes cochlea
T13762 20335-20339 WDT denotes that
T13763 20349-20358 VBD denotes expressed
T13764 20340-20348 RB denotes normally
T13765 20359-20361 NN denotes NT
T13766 20361-20362 HYPH denotes -
T13767 20362-20363 CD denotes 3
T13768 20364-20367 CC denotes and
T13769 20368-20372 VBD denotes were
T13770 20377-20387 VBN denotes innervated
T13771 20373-20376 RB denotes not
T13772 20388-20390 IN denotes by
T13773 20391-20396 DT denotes these
T13774 20397-20402 NNS denotes axons
T13775 20402-20403 . denotes .
T13776 20403-20838 sentence denotes Ectopic NT-3 supplied using osmotic pumps and adenovirus-mediated expression induce sensory axon growth during regeneration (Zhang et al. 1998, Bradbury et al. 1999, Oudega et al. 1999, Ramer et al. 2002), and induce axonal plasticity of corticospinal axons in injured adult spinal cord (Zhou et al. 2003), where the sprouting axons from the intact site cross the midline towards the NT-3 source on the lesion side of the spinal cord.
T13777 20404-20411 JJ denotes Ectopic
T13778 20412-20414 NN denotes NT
T13779 20481-20487 VBP denotes induce
T13780 20414-20415 HYPH denotes -
T13781 20415-20416 CD denotes 3
T13782 20417-20425 VBN denotes supplied
T13783 20426-20431 VBG denotes using
T13784 20432-20439 JJ denotes osmotic
T13785 20440-20445 NNS denotes pumps
T13786 20446-20449 CC denotes and
T13787 20450-20460 NN denotes adenovirus
T13788 20461-20469 VBN denotes mediated
T13789 20460-20461 HYPH denotes -
T13790 20470-20480 NN denotes expression
T13791 20488-20495 JJ denotes sensory
T13792 20501-20507 NN denotes growth
T13793 20496-20500 NN denotes axon
T13794 20508-20514 IN denotes during
T13795 20515-20527 NN denotes regeneration
T13796 20528-20529 -LRB- denotes (
T13797 20529-20534 NNP denotes Zhang
T13798 20535-20537 FW denotes et
T13799 20538-20541 FW denotes al.
T13800 20542-20546 CD denotes 1998
T13801 20546-20548 , denotes ,
T13802 20548-20556 NNP denotes Bradbury
T13803 20557-20559 FW denotes et
T13804 20560-20563 FW denotes al.
T13805 20564-20568 CD denotes 1999
T13806 20568-20570 , denotes ,
T13807 20570-20576 NNP denotes Oudega
T13808 20577-20579 FW denotes et
T13809 20580-20583 FW denotes al.
T13810 20584-20588 CD denotes 1999
T13811 20588-20590 , denotes ,
T13812 20590-20595 NNP denotes Ramer
T13813 20596-20598 FW denotes et
T13814 20599-20602 FW denotes al.
T13815 20603-20607 CD denotes 2002
T13816 20607-20608 -RRB- denotes )
T13817 20608-20610 , denotes ,
T13818 20610-20613 CC denotes and
T13819 20614-20620 VBP denotes induce
T13820 20621-20627 JJ denotes axonal
T13821 20628-20638 NN denotes plasticity
T13822 20639-20641 IN denotes of
T13823 20642-20655 JJ denotes corticospinal
T13824 20656-20661 NNS denotes axons
T13825 20662-20664 IN denotes in
T13826 20665-20672 VBN denotes injured
T13827 20686-20690 NN denotes cord
T13828 20673-20678 JJ denotes adult
T13829 20679-20685 JJ denotes spinal
T13830 20691-20692 -LRB- denotes (
T13831 20692-20696 NNP denotes Zhou
T13832 20697-20699 FW denotes et
T13833 20700-20703 FW denotes al.
T13834 20704-20708 CD denotes 2003
T13835 20708-20709 -RRB- denotes )
T13836 20709-20711 , denotes ,
T13837 20711-20716 WRB denotes where
T13838 20758-20763 VBP denotes cross
T13839 20717-20720 DT denotes the
T13840 20731-20736 NNS denotes axons
T13841 20721-20730 VBG denotes sprouting
T13842 20737-20741 IN denotes from
T13843 20742-20745 DT denotes the
T13844 20753-20757 NN denotes site
T13845 20746-20752 JJ denotes intact
T13846 20764-20767 DT denotes the
T13847 20768-20775 NN denotes midline
T13848 20776-20783 IN denotes towards
T13849 20784-20787 DT denotes the
T13850 20793-20799 NN denotes source
T13851 20788-20790 NN denotes NT
T13852 20790-20791 HYPH denotes -
T13853 20791-20792 CD denotes 3
T13854 20800-20802 IN denotes on
T13855 20803-20806 DT denotes the
T13856 20814-20818 NN denotes side
T13857 20807-20813 NN denotes lesion
T13858 20819-20821 IN denotes of
T13859 20822-20825 DT denotes the
T13860 20833-20837 NN denotes cord
T13861 20826-20832 JJ denotes spinal
T13862 20837-20838 . denotes .
T13863 20838-20988 sentence denotes Our present results are in agreement with these observations, and provide further evidence that NT-3 acts as a chemoattractant for sensory afferents.
T13864 20839-20842 PRP$ denotes Our
T13865 20851-20858 NNS denotes results
T13866 20843-20850 JJ denotes present
T13867 20859-20862 VBP denotes are
T13868 20863-20865 IN denotes in
T13869 20866-20875 NN denotes agreement
T13870 20876-20880 IN denotes with
T13871 20881-20886 DT denotes these
T13872 20887-20899 NNS denotes observations
T13873 20899-20901 , denotes ,
T13874 20901-20904 CC denotes and
T13875 20905-20912 VBP denotes provide
T13876 20913-20920 JJ denotes further
T13877 20921-20929 NN denotes evidence
T13878 20930-20934 IN denotes that
T13879 20940-20944 VBZ denotes acts
T13880 20935-20937 NN denotes NT
T13881 20937-20938 HYPH denotes -
T13882 20938-20939 CD denotes 3
T13883 20945-20947 IN denotes as
T13884 20948-20949 DT denotes a
T13885 20950-20965 NN denotes chemoattractant
T13886 20966-20969 IN denotes for
T13887 20970-20977 JJ denotes sensory
T13888 20978-20987 NNS denotes afferents
T13889 20987-20988 . denotes .
T13890 20988-21138 sentence denotes Previously, normal motor neuron innervation was rescued in NT-3 KO animals by over-expressing NT-3 selectively in their muscles (Wright et al. 1997).
T13891 20989-20999 RB denotes Previously
T13892 21037-21044 VBN denotes rescued
T13893 20999-21001 , denotes ,
T13894 21001-21007 JJ denotes normal
T13895 21021-21032 NN denotes innervation
T13896 21008-21013 NN denotes motor
T13897 21014-21020 NN denotes neuron
T13898 21033-21036 VBD denotes was
T13899 21045-21047 IN denotes in
T13900 21048-21050 NN denotes NT
T13901 21053-21055 NN denotes KO
T13902 21050-21051 HYPH denotes -
T13903 21051-21052 CD denotes 3
T13904 21056-21063 NNS denotes animals
T13905 21064-21066 IN denotes by
T13906 21067-21082 VBG denotes over-expressing
T13907 21083-21085 NN denotes NT
T13908 21085-21086 HYPH denotes -
T13909 21086-21087 CD denotes 3
T13910 21088-21099 RB denotes selectively
T13911 21100-21102 IN denotes in
T13912 21103-21108 PRP$ denotes their
T13913 21109-21116 NNS denotes muscles
T13914 21117-21118 -LRB- denotes (
T13915 21118-21124 NNP denotes Wright
T13916 21125-21127 FW denotes et
T13917 21128-21131 FW denotes al.
T13918 21132-21136 CD denotes 1997
T13919 21136-21137 -RRB- denotes )
T13920 21137-21138 . denotes .
T13921 21138-21295 sentence denotes It appears that peripheral NT-3 alone is sufficient for rescuing proprioceptive neurons in NT-3 KO animals and proper axonal pathfinding in the spinal cord.
T13922 21139-21141 PRP denotes It
T13923 21142-21149 VBZ denotes appears
T13924 21150-21154 IN denotes that
T13925 21177-21179 VBZ denotes is
T13926 21155-21165 JJ denotes peripheral
T13927 21166-21168 NN denotes NT
T13928 21168-21169 HYPH denotes -
T13929 21169-21170 CD denotes 3
T13930 21171-21176 RB denotes alone
T13931 21180-21190 JJ denotes sufficient
T13932 21191-21194 IN denotes for
T13933 21195-21203 VBG denotes rescuing
T13934 21204-21218 JJ denotes proprioceptive
T13935 21219-21226 NNS denotes neurons
T13936 21227-21229 IN denotes in
T13937 21230-21232 NN denotes NT
T13938 21235-21237 NN denotes KO
T13939 21232-21233 HYPH denotes -
T13940 21233-21234 CD denotes 3
T13941 21238-21245 NNS denotes animals
T13942 21246-21249 CC denotes and
T13943 21250-21256 JJ denotes proper
T13944 21264-21275 NN denotes pathfinding
T13945 21257-21263 JJ denotes axonal
T13946 21276-21278 IN denotes in
T13947 21279-21282 DT denotes the
T13948 21290-21294 NN denotes cord
T13949 21283-21289 JJ denotes spinal
T13950 21294-21295 . denotes .
T13951 21295-21389 sentence denotes However, it is unclear whether NT-3 is absent from the ventral spinal cords of these animals.
T13952 21296-21303 RB denotes However
T13953 21308-21310 VBZ denotes is
T13954 21303-21305 , denotes ,
T13955 21305-21307 PRP denotes it
T13956 21311-21318 JJ denotes unclear
T13957 21319-21326 IN denotes whether
T13958 21332-21334 VBZ denotes is
T13959 21327-21329 NN denotes NT
T13960 21329-21330 HYPH denotes -
T13961 21330-21331 CD denotes 3
T13962 21335-21341 JJ denotes absent
T13963 21342-21346 IN denotes from
T13964 21347-21350 DT denotes the
T13965 21366-21371 NNS denotes cords
T13966 21351-21358 JJ denotes ventral
T13967 21359-21365 JJ denotes spinal
T13968 21372-21374 IN denotes of
T13969 21375-21380 DT denotes these
T13970 21381-21388 NNS denotes animals
T13971 21388-21389 . denotes .
T13972 21389-21524 sentence denotes The possibility has been raised that motor neurons may retrogradely transport NT-3 in muscle to the spinal cord (Chen and Frank 1999).
T13973 21390-21393 DT denotes The
T13974 21394-21405 NN denotes possibility
T13975 21415-21421 VBN denotes raised
T13976 21406-21409 VBZ denotes has
T13977 21410-21414 VBN denotes been
T13978 21422-21426 IN denotes that
T13979 21458-21467 VB denotes transport
T13980 21427-21432 NN denotes motor
T13981 21433-21440 NNS denotes neurons
T13982 21441-21444 MD denotes may
T13983 21445-21457 RB denotes retrogradely
T13984 21468-21470 NN denotes NT
T13985 21470-21471 HYPH denotes -
T13986 21471-21472 CD denotes 3
T13987 21473-21475 IN denotes in
T13988 21476-21482 NN denotes muscle
T13989 21483-21485 IN denotes to
T13990 21486-21489 DT denotes the
T13991 21497-21501 NN denotes cord
T13992 21490-21496 JJ denotes spinal
T13993 21502-21503 -LRB- denotes (
T13994 21503-21507 NNP denotes Chen
T13996 21512-21517 NNP denotes Frank
T13997 21518-21522 CD denotes 1999
T13998 21522-21523 -RRB- denotes )
T13999 21523-21524 . denotes .
T14000 21524-21629 sentence denotes Assays to determine whether any NT-3 is present in the ventral horns of these mice would be informative.
T14001 21525-21531 NNS denotes Assays
T14002 21614-21616 VB denotes be
T14003 21532-21534 TO denotes to
T14004 21535-21544 VB denotes determine
T14005 21545-21552 IN denotes whether
T14006 21562-21564 VBZ denotes is
T14007 21553-21556 DT denotes any
T14008 21557-21559 NN denotes NT
T14009 21559-21560 HYPH denotes -
T14010 21560-21561 CD denotes 3
T14011 21565-21572 JJ denotes present
T14012 21573-21575 IN denotes in
T14013 21576-21579 DT denotes the
T14014 21588-21593 NNS denotes horns
T14015 21580-21587 JJ denotes ventral
T14016 21594-21596 IN denotes of
T14017 21597-21602 DT denotes these
T14018 21603-21607 NNS denotes mice
T14019 21608-21613 MD denotes would
T14020 21617-21628 JJ denotes informative
T14021 21628-21629 . denotes .
T14022 21629-21725 sentence denotes Recently, Patel et al. (2003) reported their observations on Bax/NT-3 double KO mice they bred.
T14023 21630-21638 RB denotes Recently
T14024 21660-21668 VBD denotes reported
T14025 21638-21640 , denotes ,
T14026 21640-21645 NNP denotes Patel
T14027 21646-21648 FW denotes et
T14028 21649-21652 FW denotes al.
T14029 21653-21654 -LRB- denotes (
T14030 21654-21658 CD denotes 2003
T14031 21658-21659 -RRB- denotes )
T14032 21669-21674 PRP$ denotes their
T14033 21675-21687 NNS denotes observations
T14034 21688-21690 IN denotes on
T14035 21691-21694 NN denotes Bax
T14036 21707-21709 NN denotes KO
T14037 21694-21695 HYPH denotes /
T14038 21695-21697 NN denotes NT
T14039 21697-21698 HYPH denotes -
T14040 21698-21699 CD denotes 3
T14041 21700-21706 JJ denotes double
T14042 21710-21714 NNS denotes mice
T14043 21715-21719 PRP denotes they
T14044 21720-21724 VBD denotes bred
T14045 21724-21725 . denotes .
T14046 21725-21778 sentence denotes Their results are significantly different from ours.
T14047 21726-21731 PRP$ denotes Their
T14048 21732-21739 NNS denotes results
T14049 21740-21743 VBP denotes are
T14050 21744-21757 RB denotes significantly
T14051 21758-21767 JJ denotes different
T14052 21768-21772 IN denotes from
T14053 21773-21777 PRP denotes ours
T14054 21777-21778 . denotes .
T14055 21778-21974 sentence denotes They see no proprioceptive afferents in the periphery of the double knockouts and note that central proprioceptive afferents terminate in the intermediate spinal cord without extending ventrally.
T14056 21779-21783 PRP denotes They
T14057 21784-21787 VBP denotes see
T14058 21788-21790 DT denotes no
T14059 21806-21815 NNS denotes afferents
T14060 21791-21805 JJ denotes proprioceptive
T14061 21816-21818 IN denotes in
T14062 21819-21822 DT denotes the
T14063 21823-21832 NN denotes periphery
T14064 21833-21835 IN denotes of
T14065 21836-21839 DT denotes the
T14066 21847-21856 NNS denotes knockouts
T14067 21840-21846 JJ denotes double
T14068 21857-21860 CC denotes and
T14069 21861-21865 VBP denotes note
T14070 21866-21870 IN denotes that
T14071 21904-21913 VBP denotes terminate
T14072 21871-21878 JJ denotes central
T14073 21894-21903 NNS denotes afferents
T14074 21879-21893 JJ denotes proprioceptive
T14075 21914-21916 IN denotes in
T14076 21917-21920 DT denotes the
T14077 21941-21945 NN denotes cord
T14078 21921-21933 JJ denotes intermediate
T14079 21934-21940 JJ denotes spinal
T14080 21946-21953 IN denotes without
T14081 21954-21963 VBG denotes extending
T14082 21964-21973 RB denotes ventrally
T14083 21973-21974 . denotes .
T14084 21974-22067 sentence denotes Their observations are based on PV immunostaining and DiI labeling of the peripheral nerves.
T14085 21975-21980 PRP$ denotes Their
T14086 21981-21993 NNS denotes observations
T14087 21998-22003 VBN denotes based
T14088 21994-21997 VBP denotes are
T14089 22004-22006 IN denotes on
T14090 22007-22009 NN denotes PV
T14091 22010-22024 NN denotes immunostaining
T14092 22025-22028 CC denotes and
T14093 22029-22032 NN denotes DiI
T14094 22033-22041 NN denotes labeling
T14095 22042-22044 IN denotes of
T14096 22045-22048 DT denotes the
T14097 22060-22066 NNS denotes nerves
T14098 22049-22059 JJ denotes peripheral
T14099 22066-22067 . denotes .
T14100 22067-22141 sentence denotes We noted that PV immunolabeling is diminished in our Bax/NT-3 double KOs.
T14101 22068-22070 PRP denotes We
T14102 22071-22076 VBD denotes noted
T14103 22077-22081 IN denotes that
T14104 22100-22102 VBZ denotes is
T14105 22082-22084 NN denotes PV
T14106 22085-22099 NN denotes immunolabeling
T14107 22103-22113 JJ denotes diminished
T14108 22114-22116 IN denotes in
T14109 22117-22120 PRP$ denotes our
T14110 22137-22140 NNS denotes KOs
T14111 22121-22124 NN denotes Bax
T14112 22124-22125 HYPH denotes /
T14113 22125-22127 NN denotes NT
T14114 22127-22128 HYPH denotes -
T14115 22128-22129 CD denotes 3
T14116 22130-22136 JJ denotes double
T14117 22140-22141 . denotes .
T14118 22141-22513 sentence denotes In various manipulations of the neurotrophins it has been noted that molecular markers for proprioceptive axons such as PV or calcitonin gene-related peptide for nerve growth factor–responsive axons are compromised (Ringstedt et al. 1997; Patel et al. 2000), thus PV immunostaining in Bax/NT-3 double KOs cannot reveal the extent of proprioceptive axons in the periphery.
T14119 22142-22144 IN denotes In
T14120 22200-22205 VBN denotes noted
T14121 22145-22152 JJ denotes various
T14122 22153-22166 NNS denotes manipulations
T14123 22167-22169 IN denotes of
T14124 22170-22173 DT denotes the
T14125 22174-22187 NNS denotes neurotrophins
T14126 22188-22190 PRP denotes it
T14127 22191-22194 VBZ denotes has
T14128 22195-22199 VBN denotes been
T14129 22454-22460 VB denotes reveal
T14130 22206-22210 IN denotes that
T14131 22341-22344 VBP denotes are
T14132 22211-22220 JJ denotes molecular
T14133 22221-22228 NNS denotes markers
T14134 22229-22232 IN denotes for
T14135 22233-22247 JJ denotes proprioceptive
T14136 22248-22253 NNS denotes axons
T14137 22254-22258 JJ denotes such
T14138 22259-22261 IN denotes as
T14139 22262-22264 NN denotes PV
T14140 22265-22267 CC denotes or
T14141 22268-22278 NN denotes calcitonin
T14142 22292-22299 NN denotes peptide
T14143 22279-22283 NN denotes gene
T14144 22284-22291 VBN denotes related
T14145 22283-22284 HYPH denotes -
T14146 22300-22303 IN denotes for
T14147 22304-22309 NN denotes nerve
T14148 22335-22340 NNS denotes axons
T14149 22310-22316 NN denotes growth
T14150 22317-22323 NN denotes factor
T14151 22324-22334 JJ denotes responsive
T14152 22323-22324 HYPH denotes –
T14153 22345-22356 JJ denotes compromised
T14154 22357-22358 -LRB- denotes (
T14155 22358-22367 NNP denotes Ringstedt
T14156 22368-22370 FW denotes et
T14157 22371-22374 FW denotes al.
T14158 22375-22379 CD denotes 1997
T14159 22379-22380 : denotes ;
T14160 22381-22386 NNP denotes Patel
T14161 22387-22389 FW denotes et
T14162 22390-22393 FW denotes al.
T14163 22394-22398 CD denotes 2000
T14164 22398-22399 -RRB- denotes )
T14165 22399-22401 , denotes ,
T14166 22401-22405 RB denotes thus
T14167 22406-22408 NN denotes PV
T14168 22409-22423 NN denotes immunostaining
T14169 22424-22426 IN denotes in
T14170 22427-22430 NN denotes Bax
T14171 22443-22446 NNS denotes KOs
T14172 22430-22431 HYPH denotes /
T14173 22431-22433 NN denotes NT
T14174 22433-22434 HYPH denotes -
T14175 22434-22435 CD denotes 3
T14176 22436-22442 JJ denotes double
T14177 22447-22450 MD denotes can
T14178 22450-22453 RB denotes not
T14179 22461-22464 DT denotes the
T14180 22465-22471 NN denotes extent
T14181 22472-22474 IN denotes of
T14182 22475-22489 JJ denotes proprioceptive
T14183 22490-22495 NNS denotes axons
T14184 22496-22498 IN denotes in
T14185 22499-22502 DT denotes the
T14186 22503-22512 NN denotes periphery
T14187 22512-22513 . denotes .
T14188 22513-22746 sentence denotes Seventy-three percent of retrogradely labeled gastrocnemius muscle afferents were reported to be expressing TrkC RNA in the adult rat DRG, although some of these (about 10%) may represent cutaneous innervation (McMahon et al. 1994).
T14189 22514-22521 CD denotes Seventy
T14190 22522-22527 CD denotes three
T14191 22521-22522 HYPH denotes -
T14192 22528-22535 NN denotes percent
T14193 22596-22604 VBN denotes reported
T14194 22536-22538 IN denotes of
T14195 22539-22551 RB denotes retrogradely
T14196 22552-22559 VBN denotes labeled
T14197 22581-22590 NNS denotes afferents
T14198 22560-22573 NN denotes gastrocnemius
T14199 22574-22580 NN denotes muscle
T14200 22591-22595 VBD denotes were
T14201 22605-22607 TO denotes to
T14202 22611-22621 VBG denotes expressing
T14203 22608-22610 VB denotes be
T14204 22622-22626 NN denotes TrkC
T14205 22627-22630 NN denotes RNA
T14206 22631-22633 IN denotes in
T14207 22634-22637 DT denotes the
T14208 22648-22651 NN denotes DRG
T14209 22638-22643 JJ denotes adult
T14210 22644-22647 NN denotes rat
T14211 22651-22653 , denotes ,
T14212 22653-22661 IN denotes although
T14213 22692-22701 VB denotes represent
T14214 22662-22666 DT denotes some
T14215 22667-22669 IN denotes of
T14216 22670-22675 DT denotes these
T14217 22676-22677 -LRB- denotes (
T14218 22677-22682 RB denotes about
T14219 22683-22685 CD denotes 10
T14220 22685-22686 NN denotes %
T14221 22686-22687 -RRB- denotes )
T14222 22688-22691 MD denotes may
T14223 22702-22711 JJ denotes cutaneous
T14224 22712-22723 NN denotes innervation
T14225 22724-22725 -LRB- denotes (
T14226 22725-22732 NNP denotes McMahon
T14227 22733-22735 FW denotes et
T14228 22736-22739 FW denotes al.
T14229 22740-22744 CD denotes 1994
T14230 22744-22745 -RRB- denotes )
T14231 22745-22746 . denotes .
T14232 22746-22916 sentence denotes Presently, it is not clear whether TrkC protein is also made by cutaneous afferents and if so at what stage in development this receptor is expressed by cutaneous axons.
T14233 22747-22756 RB denotes Presently
T14234 22761-22763 VBZ denotes is
T14235 22756-22758 , denotes ,
T14236 22758-22760 PRP denotes it
T14237 22764-22767 RB denotes not
T14238 22768-22773 JJ denotes clear
T14239 22774-22781 IN denotes whether
T14240 22803-22807 VBN denotes made
T14241 22782-22786 NN denotes TrkC
T14242 22787-22794 NN denotes protein
T14243 22795-22797 VBZ denotes is
T14244 22798-22802 RB denotes also
T14245 22808-22810 IN denotes by
T14246 22811-22820 JJ denotes cutaneous
T14247 22821-22830 NNS denotes afferents
T14248 22831-22834 CC denotes and
T14249 22835-22837 IN denotes if
T14250 22838-22840 RB denotes so
T14251 22887-22896 VBN denotes expressed
T14252 22841-22843 IN denotes at
T14253 22844-22848 WDT denotes what
T14254 22849-22854 NN denotes stage
T14255 22855-22857 IN denotes in
T14256 22858-22869 NN denotes development
T14257 22870-22874 DT denotes this
T14258 22875-22883 NN denotes receptor
T14259 22884-22886 VBZ denotes is
T14260 22897-22899 IN denotes by
T14261 22900-22909 JJ denotes cutaneous
T14262 22910-22915 NNS denotes axons
T14263 22915-22916 . denotes .
T14264 22916-23161 sentence denotes Based on the available evidence showing that all proprioceptive neurons are eliminated in NT-3 or TrkC null mice, we think that TrkC staining in the tibial nerve mostly represents proprioceptive axons in the vicinity of their peripheral target.
T14265 22917-22922 VBN denotes Based
T14266 23034-23039 VBP denotes think
T14267 22923-22925 IN denotes on
T14268 22926-22929 DT denotes the
T14269 22940-22948 NN denotes evidence
T14270 22930-22939 JJ denotes available
T14271 22949-22956 VBG denotes showing
T14272 22957-22961 IN denotes that
T14273 22993-23003 VBN denotes eliminated
T14274 22962-22965 DT denotes all
T14275 22981-22988 NNS denotes neurons
T14276 22966-22980 JJ denotes proprioceptive
T14277 22989-22992 VBP denotes are
T14278 23004-23006 IN denotes in
T14279 23007-23009 NN denotes NT
T14280 23020-23024 JJ denotes null
T14281 23009-23010 HYPH denotes -
T14282 23010-23011 CD denotes 3
T14283 23012-23014 CC denotes or
T14284 23015-23019 NN denotes TrkC
T14285 23025-23029 NNS denotes mice
T14286 23029-23031 , denotes ,
T14287 23031-23033 PRP denotes we
T14288 23040-23044 IN denotes that
T14289 23086-23096 VBZ denotes represents
T14290 23045-23049 NN denotes TrkC
T14291 23050-23058 NN denotes staining
T14292 23059-23061 IN denotes in
T14293 23062-23065 DT denotes the
T14294 23073-23078 NN denotes nerve
T14295 23066-23072 JJ denotes tibial
T14296 23079-23085 RB denotes mostly
T14297 23097-23111 JJ denotes proprioceptive
T14298 23112-23117 NNS denotes axons
T14299 23118-23120 IN denotes in
T14300 23121-23124 DT denotes the
T14301 23125-23133 NN denotes vicinity
T14302 23134-23136 IN denotes of
T14303 23137-23142 PRP$ denotes their
T14304 23154-23160 NN denotes target
T14305 23143-23153 JJ denotes peripheral
T14306 23160-23161 . denotes .
T14307 23161-23303 sentence denotes Altogether, our findings suggest a role for NT-3 in initiation of muscle innervation and spindle differentiation by the proprioceptive axons.
T14308 23162-23172 RB denotes Altogether
T14309 23187-23194 VBP denotes suggest
T14310 23172-23174 , denotes ,
T14311 23174-23177 PRP$ denotes our
T14312 23178-23186 NNS denotes findings
T14313 23195-23196 DT denotes a
T14314 23197-23201 NN denotes role
T14315 23202-23205 IN denotes for
T14316 23206-23208 NN denotes NT
T14317 23208-23209 HYPH denotes -
T14318 23209-23210 CD denotes 3
T14319 23211-23213 IN denotes in
T14320 23214-23224 NN denotes initiation
T14321 23225-23227 IN denotes of
T14322 23228-23234 NN denotes muscle
T14323 23235-23246 NN denotes innervation
T14324 23247-23250 CC denotes and
T14325 23251-23258 NN denotes spindle
T14326 23259-23274 NN denotes differentiation
T14327 23275-23277 IN denotes by
T14328 23278-23281 DT denotes the
T14329 23297-23302 NNS denotes axons
T14330 23282-23296 JJ denotes proprioceptive
T14331 23302-23303 . denotes .
T14332 23303-23524 sentence denotes Patel et al. (2003) examined DiI-labeled central DRG axons in the spinal cord of three E17 and two P0 cases, and report that central proprioceptive axons stop in the intermediate laminae, never entering the ventral cord.
T14333 23304-23309 NNP denotes Patel
T14334 23324-23332 VBN denotes examined
T14335 23310-23312 FW denotes et
T14336 23313-23316 FW denotes al.
T14337 23317-23318 -LRB- denotes (
T14338 23318-23322 CD denotes 2003
T14339 23322-23323 -RRB- denotes )
T14340 23333-23336 NN denotes DiI
T14341 23337-23344 VBN denotes labeled
T14342 23336-23337 HYPH denotes -
T14343 23357-23362 NNS denotes axons
T14344 23345-23352 JJ denotes central
T14345 23353-23356 NN denotes DRG
T14346 23363-23365 IN denotes in
T14347 23366-23369 DT denotes the
T14348 23377-23381 NN denotes cord
T14349 23370-23376 JJ denotes spinal
T14350 23382-23384 IN denotes of
T14351 23385-23390 CD denotes three
T14352 23391-23394 NN denotes E17
T14425 23741-23743 IN denotes at
T14426 23785-23789 VB denotes have
T14427 23744-23750 JJR denotes higher
T14428 23751-23764 NN denotes magnification
T14429 23765-23770 DT denotes these
T14430 23771-23776 NNS denotes axons
T14431 23777-23780 VBD denotes did
T14432 23781-23784 RB denotes not
T14433 23790-23798 JJ denotes terminal
T14434 23799-23806 NNS denotes boutons
T14435 23807-23810 CC denotes and
T14436 23811-23815 VBD denotes were
T14437 23831-23838 VBN denotes labeled
T14438 23816-23819 RB denotes not
T14439 23820-23830 RB denotes completely
T14440 23838-23839 . denotes .
T14441 23839-24039 sentence denotes However, with complete fills (n = 5), it was possible to trace these axons into the ventral midline and across to the contralateral side, and visualize terminal boutons at their tips (see Figure 3C).
T14442 23840-23847 RB denotes However
T14443 23881-23884 VBD denotes was
T14444 23847-23849 , denotes ,
T14445 23849-23853 IN denotes with
T14446 23854-23862 JJ denotes complete
T14447 23863-23868 NNS denotes fills
T14448 23869-23870 -LRB- denotes (
T14449 23874-23875 CD denotes 5
T14450 23870-23871 NN denotes n
T14451 23872-23873 SYM denotes =
T14452 23875-23876 -RRB- denotes )
T14453 23876-23878 , denotes ,
T14454 23878-23880 PRP denotes it
T14455 23885-23893 JJ denotes possible
T14456 23894-23896 TO denotes to
T14457 23897-23902 VB denotes trace
T14458 23903-23908 DT denotes these
T14459 23909-23914 NNS denotes axons
T14460 23915-23919 IN denotes into
T14461 23920-23923 DT denotes the
T14462 23932-23939 NN denotes midline
T14463 23924-23931 JJ denotes ventral
T14464 23940-23943 CC denotes and
T14465 23944-23950 IN denotes across
T14466 23951-23953 IN denotes to
T14467 23954-23957 DT denotes the
T14468 23972-23976 NN denotes side
T14469 23958-23971 JJ denotes contralateral
T14470 23976-23978 , denotes ,
T14471 23978-23981 CC denotes and
T14472 23982-23991 VB denotes visualize
T14473 23992-24000 JJ denotes terminal
T14474 24001-24008 NNS denotes boutons
T14475 24009-24011 IN denotes at
T14476 24012-24017 PRP$ denotes their
T14477 24018-24022 NNS denotes tips
T14478 24023-24024 -LRB- denotes (
T14479 24024-24027 VB denotes see
T14480 24028-24034 NN denotes Figure
T14481 24035-24037 NN denotes 3C
T14482 24037-24038 -RRB- denotes )
T14483 24038-24039 . denotes .
T14484 24039-24238 sentence denotes Previously, Arber et al. (2000) reported that members of the Ets family of transcription factors, Er81 and Pea3, are expressed by DRG neurons as well as motor neurons and their target muscle fibers.
T14485 24040-24050 RB denotes Previously
T14486 24072-24080 VBD denotes reported
T14487 24050-24052 , denotes ,
T14488 24052-24057 NNP denotes Arber
T14489 24058-24060 FW denotes et
T14490 24061-24064 FW denotes al.
T14491 24065-24066 -LRB- denotes (
T14492 24066-24070 CD denotes 2000
T14493 24070-24071 -RRB- denotes )
T14494 24081-24085 IN denotes that
T14495 24157-24166 VBN denotes expressed
T14496 24086-24093 NNS denotes members
T14497 24094-24096 IN denotes of
T14498 24097-24100 DT denotes the
T14499 24105-24111 NN denotes family
T14500 24101-24104 NN denotes Ets
T14501 24112-24114 IN denotes of
T14502 24115-24128 NN denotes transcription
T14503 24129-24136 NNS denotes factors
T14504 24136-24138 , denotes ,
T14505 24138-24142 NN denotes Er81
T14506 24143-24146 CC denotes and
T14507 24147-24151 NN denotes Pea3
T14508 24151-24153 , denotes ,
T14509 24153-24156 VBP denotes are
T14510 24167-24169 IN denotes by
T14511 24170-24173 NN denotes DRG
T14512 24174-24181 NNS denotes neurons
T14513 24182-24184 RB denotes as
T14514 24190-24192 IN denotes as
T14515 24185-24189 RB denotes well
T14516 24193-24198 NN denotes motor
T14517 24199-24206 NNS denotes neurons
T14518 24207-24210 CC denotes and
T14519 24211-24216 PRP$ denotes their
T14520 24231-24237 NNS denotes fibers
T14521 24217-24223 NN denotes target
T14522 24224-24230 NN denotes muscle
T14523 24237-24238 . denotes .
T14524 24238-24402 sentence denotes They found that in the spinal cord of Er81 KO mice, ventral projections of proprioceptive axons were mostly absent, and very few axons made it to the ventral cord.
T14525 24239-24243 PRP denotes They
T14526 24244-24249 VBD denotes found
T14527 24250-24254 IN denotes that
T14528 24335-24339 VBD denotes were
T14529 24255-24257 IN denotes in
T14530 24258-24261 DT denotes the
T14531 24269-24273 NN denotes cord
T14532 24262-24268 JJ denotes spinal
T14533 24274-24276 IN denotes of
T14534 24277-24281 NN denotes Er81
T14535 24282-24284 NN denotes KO
T14536 24285-24289 NNS denotes mice
T14537 24289-24291 , denotes ,
T14538 24291-24298 JJ denotes ventral
T14539 24299-24310 NNS denotes projections
T14540 24311-24313 IN denotes of
T14541 24314-24328 JJ denotes proprioceptive
T14542 24329-24334 NNS denotes axons
T14543 24340-24346 RB denotes mostly
T14544 24347-24353 JJ denotes absent
T14545 24353-24355 , denotes ,
T14546 24355-24358 CC denotes and
T14547 24359-24363 RB denotes very
T14548 24368-24373 NNS denotes axons
T14549 24364-24367 JJ denotes few
T14550 24374-24378 VBD denotes made
T14551 24379-24381 PRP denotes it
T14552 24382-24384 IN denotes to
T14553 24385-24388 DT denotes the
T14554 24397-24401 NN denotes cord
T14555 24389-24396 JJ denotes ventral
T14556 24401-24402 . denotes .
T14557 24402-24535 sentence denotes Patel et al. (2003) note that the phenotype they observed in their Bax/NT-3 double KO mice is quite similar to that of Er81 KO mice.
T14558 24403-24408 NNP denotes Patel
T14559 24423-24427 VBP denotes note
T14560 24409-24411 FW denotes et
T14561 24412-24415 FW denotes al.
T14562 24416-24417 -LRB- denotes (
T14563 24417-24421 CD denotes 2003
T14564 24421-24422 -RRB- denotes )
T14565 24428-24432 IN denotes that
T14566 24494-24496 VBZ denotes is
T14567 24433-24436 DT denotes the
T14568 24437-24446 NN denotes phenotype
T14569 24447-24451 PRP denotes they
T14570 24452-24460 VBD denotes observed
T14571 24461-24463 IN denotes in
T14572 24464-24469 PRP$ denotes their
T14573 24489-24493 NNS denotes mice
T14574 24470-24473 NN denotes Bax
T14575 24486-24488 NN denotes KO
T14576 24473-24474 HYPH denotes /
T14577 24474-24476 NN denotes NT
T14578 24476-24477 HYPH denotes -
T14579 24477-24478 CD denotes 3
T14580 24479-24485 JJ denotes double
T14581 24497-24502 RB denotes quite
T14582 24503-24510 JJ denotes similar
T14583 24511-24513 IN denotes to
T14584 24514-24518 DT denotes that
T14585 24519-24521 IN denotes of
T14586 24522-24526 NN denotes Er81
T14587 24527-24529 NN denotes KO
T14588 24530-24534 NNS denotes mice
T14589 24534-24535 . denotes .
T14590 24535-24617 sentence denotes They provide evidence that NT-3 induces Er81 expression in DRG explants in vitro.
T14591 24536-24540 PRP denotes They
T14592 24541-24548 VBP denotes provide
T14593 24549-24557 NN denotes evidence
T14594 24558-24562 IN denotes that
T14595 24568-24575 VBZ denotes induces
T14596 24563-24565 NN denotes NT
T14597 24565-24566 HYPH denotes -
T14598 24566-24567 CD denotes 3
T14599 24576-24580 NN denotes Er81
T14600 24581-24591 NN denotes expression
T14601 24592-24594 IN denotes in
T14602 24595-24598 NN denotes DRG
T14603 24599-24607 NNS denotes explants
T14604 24608-24610 FW denotes in
T14605 24611-24616 FW denotes vitro
T14606 24616-24617 . denotes .
T14607 24617-24840 sentence denotes Patel et al. (2003) report that Er81 mRNA expression is diminished (but not abolished) in both NT-3 KO and Bax/NT-3 double KO mice, while their immunohistochemistry shows much less protein expression in the double KO mice.
T14608 24618-24623 NNP denotes Patel
T14609 24638-24644 VBP denotes report
T14610 24624-24626 FW denotes et
T14611 24627-24630 FW denotes al.
T14612 24631-24632 -LRB- denotes (
T14613 24632-24636 CD denotes 2003
T14614 24636-24637 -RRB- denotes )
T14615 24645-24649 IN denotes that
T14616 24674-24684 VBN denotes diminished
T14617 24650-24654 NN denotes Er81
T14618 24660-24670 NN denotes expression
T14619 24655-24659 NN denotes mRNA
T14620 24671-24673 VBZ denotes is
T14621 24685-24686 -LRB- denotes (
T14622 24686-24689 CC denotes but
T14623 24690-24693 RB denotes not
T14624 24694-24703 VBN denotes abolished
T14625 24703-24704 -RRB- denotes )
T14626 24705-24707 IN denotes in
T14627 24708-24712 CC denotes both
T14628 24744-24748 NNS denotes mice
T14629 24713-24715 NN denotes NT
T14630 24718-24720 NN denotes KO
T14631 24715-24716 HYPH denotes -
T14632 24716-24717 CD denotes 3
T14633 24721-24724 CC denotes and
T14634 24725-24728 NN denotes Bax
T14635 24741-24743 NN denotes KO
T14636 24728-24729 HYPH denotes /
T14637 24729-24731 NN denotes NT
T14638 24731-24732 HYPH denotes -
T14639 24732-24733 CD denotes 3
T14640 24734-24740 JJ denotes double
T14641 24748-24750 , denotes ,
T14642 24750-24755 IN denotes while
T14643 24783-24788 VBZ denotes shows
T14644 24756-24761 PRP$ denotes their
T14645 24762-24782 NN denotes immunohistochemistry
T14646 24789-24793 RB denotes much
T14647 24794-24798 JJR denotes less
T14648 24807-24817 NN denotes expression
T14649 24799-24806 NN denotes protein
T14650 24818-24820 IN denotes in
T14651 24821-24824 DT denotes the
T14652 24835-24839 NNS denotes mice
T14653 24825-24831 JJ denotes double
T14654 24832-24834 NN denotes KO
T14655 24839-24840 . denotes .
T14656 24840-25054 sentence denotes It is highly possible that a small but considerable number of DRG cells express the transcription factor Er81 and that their axons grow beyond the intermediate levels of the spinal cord in Bax/NT-3 double KO mice.
T14657 24841-24843 PRP denotes It
T14658 24844-24846 VBZ denotes is
T14659 24847-24853 RB denotes highly
T14660 24854-24862 JJ denotes possible
T14661 24863-24867 IN denotes that
T14662 24913-24920 VBP denotes express
T14663 24868-24869 DT denotes a
T14664 24893-24899 NN denotes number
T14665 24870-24875 JJ denotes small
T14666 24876-24879 CC denotes but
T14667 24880-24892 JJ denotes considerable
T14668 24900-24902 IN denotes of
T14669 24903-24906 NN denotes DRG
T14670 24907-24912 NNS denotes cells
T14671 24921-24924 DT denotes the
T14672 24939-24945 NN denotes factor
T14673 24925-24938 NN denotes transcription
T14674 24946-24950 NN denotes Er81
T14675 24951-24954 CC denotes and
T14676 24955-24959 IN denotes that
T14677 24972-24976 VB denotes grow
T14678 24960-24965 PRP$ denotes their
T14679 24966-24971 NNS denotes axons
T14680 24977-24983 IN denotes beyond
T14681 24984-24987 DT denotes the
T14682 25001-25007 NNS denotes levels
T14683 24988-25000 JJ denotes intermediate
T14684 25008-25010 IN denotes of
T14685 25011-25014 DT denotes the
T14686 25022-25026 NN denotes cord
T14687 25015-25021 JJ denotes spinal
T14688 25027-25029 IN denotes in
T14689 25030-25033 NN denotes Bax
T14690 25046-25048 NN denotes KO
T14691 25033-25034 HYPH denotes /
T14692 25034-25036 NN denotes NT
T14693 25036-25037 HYPH denotes -
T14694 25037-25038 CD denotes 3
T14695 25039-25045 JJ denotes double
T14696 25049-25053 NNS denotes mice
T14697 25053-25054 . denotes .
T14698 25054-25332 sentence denotes While the phenotype of Er81 KO mice is quite dramatic, and most proprioceptive axons stop within the intermediate spinal cord, it is important to note that a few axons still find their way to the ventral spinal cord and target properly to the motor neurons (Arber et al. 2000).
T14699 25055-25060 IN denotes While
T14700 25091-25093 VBZ denotes is
T14701 25061-25064 DT denotes the
T14702 25065-25074 NN denotes phenotype
T14703 25075-25077 IN denotes of
T14704 25078-25082 NN denotes Er81
T14705 25083-25085 NN denotes KO
T14706 25086-25090 NNS denotes mice
T14707 25185-25187 VBZ denotes is
T14708 25094-25099 RB denotes quite
T14709 25100-25108 JJ denotes dramatic
T14710 25108-25110 , denotes ,
T14711 25110-25113 CC denotes and
T14712 25114-25118 JJS denotes most
T14713 25134-25139 NNS denotes axons
T14714 25119-25133 JJ denotes proprioceptive
T14715 25140-25144 VB denotes stop
T14716 25145-25151 IN denotes within
T14717 25152-25155 DT denotes the
T14718 25176-25180 NN denotes cord
T14719 25156-25168 JJ denotes intermediate
T14720 25169-25175 JJ denotes spinal
T14721 25180-25182 , denotes ,
T14722 25182-25184 PRP denotes it
T14723 25188-25197 JJ denotes important
T14724 25198-25200 TO denotes to
T14725 25201-25205 VB denotes note
T14726 25206-25210 IN denotes that
T14727 25229-25233 VBP denotes find
T14728 25211-25212 DT denotes a
T14729 25217-25222 NNS denotes axons
T14730 25213-25216 JJ denotes few
T14731 25223-25228 RB denotes still
T14732 25234-25239 PRP$ denotes their
T14733 25240-25243 NN denotes way
T14734 25244-25246 IN denotes to
T14735 25247-25250 DT denotes the
T14736 25266-25270 NN denotes cord
T14737 25251-25258 JJ denotes ventral
T14738 25259-25265 JJ denotes spinal
T14739 25271-25274 CC denotes and
T14740 25275-25281 VBP denotes target
T14741 25282-25290 RB denotes properly
T14742 25291-25293 IN denotes to
T14743 25294-25297 DT denotes the
T14744 25304-25311 NNS denotes neurons
T14745 25298-25303 NN denotes motor
T14746 25312-25313 -LRB- denotes (
T14747 25313-25318 NNP denotes Arber
T14748 25319-25321 FW denotes et
T14749 25322-25325 FW denotes al.
T14750 25326-25330 CD denotes 2000
T14751 25330-25331 -RRB- denotes )
T14752 25331-25332 . denotes .
T14753 25332-25474 sentence denotes Patel et al. (2003) also present observations from islet2DTA mice, which lack a significant portion of the motor neurons in the ventral cord.
T14754 25333-25338 NNP denotes Patel
T14755 25358-25365 VBP denotes present
T14756 25339-25341 FW denotes et
T14757 25342-25345 FW denotes al.
T14758 25346-25347 -LRB- denotes (
T14759 25347-25351 CD denotes 2003
T14760 25351-25352 -RRB- denotes )
T14761 25353-25357 RB denotes also
T14762 25366-25378 NNS denotes observations
T14763 25379-25383 IN denotes from
T14764 25384-25393 NN denotes islet2DTA
T14765 25394-25398 NNS denotes mice
T14766 25398-25400 , denotes ,
T14767 25400-25405 WDT denotes which
T14768 25406-25410 VBP denotes lack
T14769 25411-25412 DT denotes a
T14770 25425-25432 NN denotes portion
T14771 25413-25424 JJ denotes significant
T14772 25433-25435 IN denotes of
T14773 25436-25439 DT denotes the
T14774 25446-25453 NNS denotes neurons
T14775 25440-25445 NN denotes motor
T14776 25454-25456 IN denotes in
T14777 25457-25460 DT denotes the
T14778 25469-25473 NN denotes cord
T14779 25461-25468 JJ denotes ventral
T14780 25473-25474 . denotes .
T14781 25474-25540 sentence denotes In these mice PV immunostaining shows axons in the ventral horns.
T14782 25475-25477 IN denotes In
T14783 25507-25512 VBZ denotes shows
T14784 25478-25483 DT denotes these
T14785 25484-25488 NNS denotes mice
T14786 25489-25491 NN denotes PV
T14787 25492-25506 NN denotes immunostaining
T14788 25513-25518 NNS denotes axons
T14789 25519-25521 IN denotes in
T14790 25522-25525 DT denotes the
T14791 25534-25539 NNS denotes horns
T14792 25526-25533 JJ denotes ventral
T14793 25539-25540 . denotes .
T14794 25540-25715 sentence denotes Patel et al. argue that since motor neurons are absent in these mice, NT-3 secreted by them could not be a signal for proprioceptive axons to enter the lateral motor columns.
T14795 25541-25546 NNP denotes Patel
T14796 25554-25559 VBP denotes argue
T14797 25547-25549 FW denotes et
T14798 25550-25553 FW denotes al.
T14799 25560-25564 IN denotes that
T14800 25643-25645 VB denotes be
T14801 25565-25570 IN denotes since
T14802 25585-25588 VBP denotes are
T14803 25571-25576 NN denotes motor
T14804 25577-25584 NNS denotes neurons
T14805 25589-25595 JJ denotes absent
T14806 25596-25598 IN denotes in
T14807 25599-25604 DT denotes these
T14808 25605-25609 NNS denotes mice
T14809 25609-25611 , denotes ,
T14810 25611-25613 NN denotes NT
T14811 25613-25614 HYPH denotes -
T14812 25614-25615 CD denotes 3
T14813 25616-25624 VBN denotes secreted
T14814 25625-25627 IN denotes by
T14815 25628-25632 PRP denotes them
T14816 25633-25638 MD denotes could
T14817 25639-25642 RB denotes not
T14818 25646-25647 DT denotes a
T14819 25648-25654 NN denotes signal
T14820 25655-25658 IN denotes for
T14821 25683-25688 VB denotes enter
T14822 25659-25673 JJ denotes proprioceptive
T14823 25674-25679 NNS denotes axons
T14824 25680-25682 TO denotes to
T14825 25689-25692 DT denotes the
T14826 25707-25714 NNS denotes columns
T14827 25693-25700 JJ denotes lateral
T14828 25701-25706 NN denotes motor
T14829 25714-25715 . denotes .
T14830 25715-26011 sentence denotes However, there is no evidence showing that NT-3 mRNA or protein expressed in the ventral spinal cord is exclusively from motor neurons, and there are no available data indicating that in islet2DTA mice, NT-3 expression in the ventral spinal cord is abolished (Yang et al. 2001; Pun et al. 2002).
T14831 25716-25723 RB denotes However
T14832 25731-25733 VBZ denotes is
T14833 25723-25725 , denotes ,
T14834 25725-25730 EX denotes there
T14835 25734-25736 DT denotes no
T14836 25737-25745 NN denotes evidence
T14837 25746-25753 VBG denotes showing
T14838 25754-25758 IN denotes that
T14839 25817-25819 VBZ denotes is
T14840 25759-25761 NN denotes NT
T14841 25764-25768 NN denotes mRNA
T14842 25761-25762 HYPH denotes -
T14843 25762-25763 CD denotes 3
T14844 25769-25771 CC denotes or
T14845 25772-25779 NN denotes protein
T14846 25780-25789 VBN denotes expressed
T14847 25790-25792 IN denotes in
T14848 25793-25796 DT denotes the
T14849 25812-25816 NN denotes cord
T14850 25797-25804 JJ denotes ventral
T14851 25805-25811 JJ denotes spinal
T14852 25820-25831 RB denotes exclusively
T14853 25832-25836 IN denotes from
T14854 25837-25842 NN denotes motor
T14855 25843-25850 NNS denotes neurons
T14856 25850-25852 , denotes ,
T14857 25852-25855 CC denotes and
T14858 25856-25861 EX denotes there
T14859 25862-25865 VBP denotes are
T14860 25866-25868 DT denotes no
T14861 25879-25883 NNS denotes data
T14862 25869-25878 JJ denotes available
T14863 25884-25894 VBG denotes indicating
T14864 25895-25899 IN denotes that
T14865 25965-25974 VBN denotes abolished
T14866 25900-25902 IN denotes in
T14867 25903-25912 NN denotes islet2DTA
T14868 25913-25917 NNS denotes mice
T14869 25917-25919 , denotes ,
T14870 25919-25921 NN denotes NT
T14871 25924-25934 NN denotes expression
T14872 25921-25922 HYPH denotes -
T14873 25922-25923 CD denotes 3
T14874 25935-25937 IN denotes in
T14875 25938-25941 DT denotes the
T14876 25957-25961 NN denotes cord
T14877 25942-25949 JJ denotes ventral
T14878 25950-25956 JJ denotes spinal
T14879 25962-25964 VBZ denotes is
T14880 25975-25976 -LRB- denotes (
T14881 25976-25980 NNP denotes Yang
T14882 25981-25983 FW denotes et
T14883 25984-25987 FW denotes al.
T14884 25988-25992 CD denotes 2001
T14885 25992-25993 : denotes ;
T14886 25994-25997 NNP denotes Pun
T14887 25998-26000 FW denotes et
T14888 26001-26004 FW denotes al.
T14889 26005-26009 CD denotes 2002
T14890 26009-26010 -RRB- denotes )
T14891 26010-26011 . denotes .
T14892 26011-26188 sentence denotes Studies in embryonic mice reported NT-3 mRNA in the ventral horns of the spinal cord, but it is not definitive that both mRNA and protein are expressed solely by motor neurons.
T14893 26012-26019 NNS denotes Studies
T14894 26038-26046 VBD denotes reported
T14895 26020-26022 IN denotes in
T14896 26023-26032 JJ denotes embryonic
T14897 26033-26037 NNS denotes mice
T14898 26047-26049 NN denotes NT
T14899 26052-26056 NN denotes mRNA
T14900 26049-26050 HYPH denotes -
T14901 26050-26051 CD denotes 3
T14902 26057-26059 IN denotes in
T14903 26060-26063 DT denotes the
T14904 26072-26077 NNS denotes horns
T14905 26064-26071 JJ denotes ventral
T14906 26078-26080 IN denotes of
T14907 26081-26084 DT denotes the
T14908 26092-26096 NN denotes cord
T14909 26085-26091 JJ denotes spinal
T14910 26096-26098 , denotes ,
T14911 26098-26101 CC denotes but
T14912 26102-26104 PRP denotes it
T14913 26105-26107 VBZ denotes is
T14914 26108-26111 RB denotes not
T14915 26112-26122 JJ denotes definitive
T14916 26123-26127 IN denotes that
T14917 26154-26163 VBN denotes expressed
T14918 26128-26132 CC denotes both
T14919 26133-26137 NN denotes mRNA
T14920 26138-26141 CC denotes and
T14921 26142-26149 NN denotes protein
T14922 26150-26153 VBP denotes are
T14923 26164-26170 RB denotes solely
T14924 26171-26173 IN denotes by
T14925 26174-26179 NN denotes motor
T14926 26180-26187 NNS denotes neurons
T14927 26187-26188 . denotes .
T14928 26188-26369 sentence denotes In the adult spinal cord, while motor neurons express high levels of NT-3, other cells, including glia, also express it (Zhou and Rush 1994; Dreyfus et al. 1999; Buck et al. 2000).
T14929 26189-26191 IN denotes In
T14930 26298-26305 VBP denotes express
T14931 26192-26195 DT denotes the
T14932 26209-26213 NN denotes cord
T14933 26196-26201 JJ denotes adult
T14934 26202-26208 JJ denotes spinal
T14935 26213-26215 , denotes ,
T14936 26215-26220 IN denotes while
T14937 26235-26242 VBP denotes express
T14938 26221-26226 NN denotes motor
T14939 26227-26234 NNS denotes neurons
T14940 26243-26247 JJ denotes high
T14941 26248-26254 NNS denotes levels
T14942 26255-26257 IN denotes of
T14943 26258-26260 NN denotes NT
T14944 26260-26261 HYPH denotes -
T14945 26261-26262 CD denotes 3
T14946 26262-26264 , denotes ,
T14947 26264-26269 JJ denotes other
T14948 26270-26275 NNS denotes cells
T14949 26275-26277 , denotes ,
T14950 26277-26286 VBG denotes including
T14951 26287-26291 NN denotes glia
T14952 26291-26293 , denotes ,
T14953 26293-26297 RB denotes also
T14954 26306-26308 PRP denotes it
T14955 26309-26310 -LRB- denotes (
T14956 26310-26314 NNP denotes Zhou
T14957 26315-26318 CC denotes and
T14958 26319-26323 NNP denotes Rush
T14959 26324-26328 CD denotes 1994
T14960 26328-26329 : denotes ;
T14961 26330-26337 NNP denotes Dreyfus
T14962 26338-26340 FW denotes et
T14963 26341-26344 FW denotes al.
T14964 26345-26349 CD denotes 1999
T14965 26349-26350 : denotes ;
T14966 26351-26355 NNP denotes Buck
T14967 26356-26358 FW denotes et
T14968 26359-26362 FW denotes al.
T14969 26363-26367 CD denotes 2000
T14970 26367-26368 -RRB- denotes )
T14971 26368-26369 . denotes .
T14972 26369-26619 sentence denotes Our present results, along with those from transgenic mice with NT-3 over-expression in ectopic regions of the spinal cord (Ringstedt et al. 1997), argue for a role of NT-3 in chemoattractant axon guidance of proprioceptive axons in the spinal cord.
T14973 26370-26373 PRP$ denotes Our
T14974 26382-26389 NNS denotes results
T14975 26374-26381 JJ denotes present
T14976 26518-26523 VBP denotes argue
T14977 26389-26391 , denotes ,
T14978 26391-26396 IN denotes along
T14979 26397-26401 IN denotes with
T14980 26402-26407 DT denotes those
T14981 26408-26412 IN denotes from
T14982 26413-26423 JJ denotes transgenic
T14983 26424-26428 NNS denotes mice
T14984 26429-26433 IN denotes with
T14985 26434-26436 NN denotes NT
T14986 26439-26454 NN denotes over-expression
T14987 26436-26437 HYPH denotes -
T14988 26437-26438 CD denotes 3
T14989 26455-26457 IN denotes in
T14990 26458-26465 JJ denotes ectopic
T14991 26466-26473 NNS denotes regions
T14992 26474-26476 IN denotes of
T14993 26477-26480 DT denotes the
T14994 26488-26492 NN denotes cord
T14995 26481-26487 JJ denotes spinal
T14996 26493-26494 -LRB- denotes (
T14997 26494-26503 NNP denotes Ringstedt
T14998 26504-26506 FW denotes et
T14999 26507-26510 FW denotes al.
T15000 26511-26515 CD denotes 1997
T15001 26515-26516 -RRB- denotes )
T15002 26516-26518 , denotes ,
T15003 26524-26527 IN denotes for
T15004 26528-26529 DT denotes a
T15005 26530-26534 NN denotes role
T15006 26535-26537 IN denotes of
T15007 26538-26540 NN denotes NT
T15008 26540-26541 HYPH denotes -
T15009 26541-26542 CD denotes 3
T15010 26543-26545 IN denotes in
T15011 26546-26561 NN denotes chemoattractant
T15012 26567-26575 NN denotes guidance
T15013 26562-26566 NN denotes axon
T15014 26576-26578 IN denotes of
T15015 26579-26593 JJ denotes proprioceptive
T15016 26594-26599 NNS denotes axons
T15017 26600-26602 IN denotes in
T15018 26603-26606 DT denotes the
T15019 26614-26618 NN denotes cord
T15020 26607-26613 JJ denotes spinal
T15021 26618-26619 . denotes .
T15022 26619-26724 sentence denotes Finally, in culture assays, we see a strong chemoattraction of DRG neurons to localized sources of NT-3.
T15023 26620-26627 RB denotes Finally
T15024 26651-26654 VBP denotes see
T15025 26627-26629 , denotes ,
T15026 26629-26631 IN denotes in
T15027 26632-26639 NN denotes culture
T15028 26640-26646 NNS denotes assays
T15029 26646-26648 , denotes ,
T15030 26648-26650 PRP denotes we
T15031 26655-26656 DT denotes a
T15032 26664-26679 NN denotes chemoattraction
T15033 26657-26663 JJ denotes strong
T15034 26680-26682 IN denotes of
T15035 26683-26686 NN denotes DRG
T15036 26687-26694 NNS denotes neurons
T15037 26695-26697 IN denotes to
T15038 26698-26707 JJ denotes localized
T15039 26708-26715 NNS denotes sources
T15040 26716-26718 IN denotes of
T15041 26719-26721 NN denotes NT
T15042 26721-26722 HYPH denotes -
T15043 26722-26723 CD denotes 3
T15044 26723-26724 . denotes .
T15045 26724-26881 sentence denotes This response is seen in WT, Bax null and in p75 null DRG explants, and in the absence of any other neurotrophins or target-derived axon guidance molecules.
T15046 26725-26729 DT denotes This
T15047 26730-26738 NN denotes response
T15048 26742-26746 VBN denotes seen
T15049 26739-26741 VBZ denotes is
T15050 26747-26749 IN denotes in
T15051 26750-26752 NN denotes WT
T15052 26754-26757 NN denotes Bax
T15053 26752-26754 , denotes ,
T15054 26758-26762 JJ denotes null
T15055 26763-26766 CC denotes and
T15056 26767-26769 IN denotes in
T15057 26770-26773 NN denotes p75
T15058 26774-26778 JJ denotes null
T15059 26779-26782 NN denotes DRG
T15060 26783-26791 NNS denotes explants
T15061 26791-26793 , denotes ,
T15062 26793-26796 CC denotes and
T15063 26797-26799 IN denotes in
T15064 26800-26803 DT denotes the
T15065 26804-26811 NN denotes absence
T15066 26812-26814 IN denotes of
T15067 26815-26818 DT denotes any
T15068 26825-26838 NNS denotes neurotrophins
T15069 26819-26824 JJ denotes other
T15070 26839-26841 CC denotes or
T15071 26842-26848 NN denotes target
T15072 26849-26856 VBN denotes derived
T15073 26848-26849 HYPH denotes -
T15074 26871-26880 NNS denotes molecules
T15075 26857-26861 NN denotes axon
T15076 26862-26870 NN denotes guidance
T15077 26880-26881 . denotes .
T15078 26881-27016 sentence denotes Furthermore, in vitro, sensory axon response to NT-3 does not appear to be dose-dependent (Ringstedt et al. 1997; Tucker et al. 2001).
T15079 26882-26893 RB denotes Furthermore
T15080 26944-26950 VB denotes appear
T15081 26893-26895 , denotes ,
T15082 26895-26897 FW denotes in
T15083 26898-26903 FW denotes vitro
T15084 26903-26905 , denotes ,
T15085 26905-26912 JJ denotes sensory
T15086 26913-26917 NN denotes axon
T15087 26918-26926 NN denotes response
T15088 26927-26929 IN denotes to
T15089 26930-26932 NN denotes NT
T15090 26932-26933 HYPH denotes -
T15091 26933-26934 CD denotes 3
T15092 26935-26939 VBZ denotes does
T15093 26940-26943 RB denotes not
T15094 26951-26953 TO denotes to
T15095 26954-26956 VB denotes be
T15096 26957-26961 NN denotes dose
T15097 26962-26971 JJ denotes dependent
T15098 26961-26962 HYPH denotes -
T15099 26972-26973 -LRB- denotes (
T15100 26973-26982 NNP denotes Ringstedt
T15101 26983-26985 FW denotes et
T15102 26986-26989 FW denotes al.
T15103 26990-26994 CD denotes 1997
T15104 26994-26995 : denotes ;
T15105 26996-27002 NNP denotes Tucker
T15106 27003-27005 FW denotes et
T15107 27006-27009 FW denotes al.
T15108 27010-27014 CD denotes 2001
T15109 27014-27015 -RRB- denotes )
T15110 27015-27016 . denotes .
T15111 27016-27185 sentence denotes NT-3 is capable of attracting axons along distances of up to 1 mm in collagen gel matrix, covering the physiological range it needs to attract axons during development.
T15112 27017-27019 NN denotes NT
T15113 27022-27024 VBZ denotes is
T15114 27019-27020 HYPH denotes -
T15115 27020-27021 CD denotes 3
T15116 27025-27032 JJ denotes capable
T15117 27033-27035 IN denotes of
T15118 27036-27046 VBG denotes attracting
T15119 27047-27052 NNS denotes axons
T15120 27053-27058 IN denotes along
T15121 27059-27068 NNS denotes distances
T15122 27069-27071 IN denotes of
T15123 27072-27074 IN denotes up
T15124 27078-27079 CD denotes 1
T15125 27075-27077 IN denotes to
T15126 27080-27082 NN denotes mm
T15127 27083-27085 IN denotes in
T15128 27086-27094 NN denotes collagen
T15129 27099-27105 NN denotes matrix
T15130 27095-27098 NN denotes gel
T15131 27105-27107 , denotes ,
T15132 27107-27115 VBG denotes covering
T15133 27116-27119 DT denotes the
T15134 27134-27139 NN denotes range
T15135 27120-27133 JJ denotes physiological
T15136 27140-27142 PRP denotes it
T15137 27143-27148 VBZ denotes needs
T15138 27149-27151 TO denotes to
T15139 27152-27159 VB denotes attract
T15140 27160-27165 NNS denotes axons
T15141 27166-27172 IN denotes during
T15142 27173-27184 NN denotes development
T15143 27184-27185 . denotes .
T15144 27185-27436 sentence denotes Previous studies with exogenous or local applications of NT-3 to developing primary sensory axons have indicated that this neurotrophin can attract and induce axonal branching (Ulupınar et al. 2000; Özdinler and Erzurumlu 2001, Özdinler et al. 2004).
T15145 27186-27194 JJ denotes Previous
T15146 27195-27202 NNS denotes studies
T15147 27289-27298 VBN denotes indicated
T15148 27203-27207 IN denotes with
T15149 27208-27217 JJ denotes exogenous
T15150 27227-27239 NNS denotes applications
T15151 27218-27220 CC denotes or
T15152 27221-27226 JJ denotes local
T15153 27240-27242 IN denotes of
T15154 27243-27245 NN denotes NT
T15155 27245-27246 HYPH denotes -
T15156 27246-27247 CD denotes 3
T15157 27248-27250 IN denotes to
T15158 27251-27261 JJ denotes developing
T15159 27278-27283 NNS denotes axons
T15160 27262-27269 JJ denotes primary
T15161 27270-27277 JJ denotes sensory
T15162 27284-27288 VBP denotes have
T15163 27299-27303 IN denotes that
T15164 27326-27333 VB denotes attract
T15165 27304-27308 DT denotes this
T15166 27309-27321 NN denotes neurotrophin
T15167 27322-27325 MD denotes can
T15168 27334-27337 CC denotes and
T15169 27338-27344 VB denotes induce
T15170 27345-27351 JJ denotes axonal
T15171 27352-27361 NN denotes branching
T15172 27362-27363 -LRB- denotes (
T15173 27363-27371 NNP denotes Ulupınar
T15174 27372-27374 FW denotes et
T15175 27375-27378 FW denotes al.
T15176 27379-27383 CD denotes 2000
T15177 27383-27384 : denotes ;
T15178 27385-27393 NNP denotes Özdinler
T15179 27394-27397 CC denotes and
T15180 27398-27407 NNP denotes Erzurumlu
T15181 27408-27412 CD denotes 2001
T15182 27412-27414 , denotes ,
T15183 27414-27422 NNP denotes Özdinler
T15184 27423-27425 FW denotes et
T15185 27426-27429 FW denotes al.
T15186 27430-27434 CD denotes 2004
T15187 27434-27435 -RRB- denotes )
T15188 27435-27436 . denotes .
T15189 27436-27587 sentence denotes Along the monosynaptic stretch reflex pathway, only Wnt-3 has been implicated as an axon arborization factor in the spinal cord (Krylova et al. 2002).
T15190 27437-27442 IN denotes Along
T15191 27504-27514 VBN denotes implicated
T15192 27443-27446 DT denotes the
T15193 27475-27482 NN denotes pathway
T15194 27447-27459 JJ denotes monosynaptic
T15195 27460-27467 NN denotes stretch
T15196 27468-27474 NN denotes reflex
T15197 27482-27484 , denotes ,
T15198 27484-27488 RB denotes only
T15199 27489-27492 NN denotes Wnt
T15200 27492-27493 HYPH denotes -
T15201 27493-27494 CD denotes 3
T15202 27495-27498 VBZ denotes has
T15203 27499-27503 VBN denotes been
T15204 27515-27517 IN denotes as
T15205 27518-27520 DT denotes an
T15206 27539-27545 NN denotes factor
T15207 27521-27525 NN denotes axon
T15208 27526-27538 NN denotes arborization
T15209 27546-27548 IN denotes in
T15210 27549-27552 DT denotes the
T15211 27560-27564 NN denotes cord
T15212 27553-27559 JJ denotes spinal
T15213 27565-27566 -LRB- denotes (
T15214 27566-27573 NNP denotes Krylova
T15215 27574-27576 FW denotes et
T15216 27577-27580 FW denotes al.
T15217 27581-27585 CD denotes 2002
T15218 27585-27586 -RRB- denotes )
T15219 27586-27587 . denotes .
T15220 27587-27779 sentence denotes Another molecule, Slit2, expressed in the midline and by motor neurons (Wang et al. 1999) is capable of inducing axonal branching (Nguyen Ba-Charvet et al. 2001; Özdinler and Erzurumlu 2002).
T15221 27588-27595 DT denotes Another
T15222 27596-27604 NN denotes molecule
T15223 27678-27680 VBZ denotes is
T15224 27604-27606 , denotes ,
T15225 27606-27611 NN denotes Slit2
T15226 27611-27613 , denotes ,
T15227 27613-27622 VBN denotes expressed
T15228 27623-27625 IN denotes in
T15229 27626-27629 DT denotes the
T15230 27630-27637 NN denotes midline
T15231 27638-27641 CC denotes and
T15232 27642-27644 IN denotes by
T15233 27645-27650 NN denotes motor
T15234 27651-27658 NNS denotes neurons
T15235 27659-27660 -LRB- denotes (
T15236 27660-27664 NNP denotes Wang
T15237 27665-27667 FW denotes et
T15238 27668-27671 FW denotes al.
T15239 27672-27676 CD denotes 1999
T15240 27676-27677 -RRB- denotes )
T15241 27681-27688 JJ denotes capable
T15242 27689-27691 IN denotes of
T15243 27692-27700 VBG denotes inducing
T15244 27701-27707 JJ denotes axonal
T15245 27708-27717 NN denotes branching
T15246 27718-27719 -LRB- denotes (
T15247 27719-27725 NNP denotes Nguyen
T15248 27726-27728 NNP denotes Ba
T15249 27728-27729 HYPH denotes -
T15250 27729-27736 NNP denotes Charvet
T15251 27737-27739 FW denotes et
T15252 27740-27743 FW denotes al.
T15253 27744-27748 CD denotes 2001
T15254 27748-27749 : denotes ;
T15255 27750-27758 NNP denotes Özdinler
T15256 27759-27762 CC denotes and
T15257 27763-27772 NNP denotes Erzurumlu
T15258 27773-27777 CD denotes 2002
T15259 27777-27778 -RRB- denotes )
T15260 27778-27779 . denotes .
T15261 27779-27933 sentence denotes DRG neurons express Robo receptors, which bind to Slits, and proprioceptive axons are therefore capable of responding to Slit signals (Wang et al. 1999).
T15262 27780-27783 NN denotes DRG
T15263 27784-27791 NNS denotes neurons
T15264 27792-27799 VBP denotes express
T15265 27800-27804 NN denotes Robo
T15266 27805-27814 NNS denotes receptors
T15267 27814-27816 , denotes ,
T15268 27816-27821 WDT denotes which
T15269 27822-27826 VBP denotes bind
T15270 27827-27829 IN denotes to
T15271 27830-27835 NNS denotes Slits
T15272 27835-27837 , denotes ,
T15273 27837-27840 CC denotes and
T15274 27841-27855 JJ denotes proprioceptive
T15275 27856-27861 NNS denotes axons
T15276 27862-27865 VBP denotes are
T15277 27866-27875 RB denotes therefore
T15278 27876-27883 JJ denotes capable
T15279 27884-27886 IN denotes of
T15280 27887-27897 VBG denotes responding
T15281 27898-27900 IN denotes to
T15282 27901-27905 NN denotes Slit
T15283 27906-27913 NNS denotes signals
T15284 27914-27915 -LRB- denotes (
T15285 27915-27919 NNP denotes Wang
T15286 27920-27922 FW denotes et
T15287 27923-27926 FW denotes al.
T15288 27927-27931 CD denotes 1999
T15289 27931-27932 -RRB- denotes )
T15290 27932-27933 . denotes .
T15291 27933-28149 sentence denotes Slit2 does not cause repulsion of NT-3-responsive DRG axons in vitro (Nguyen Ba-Charvet et al. 2001), but causes ectopic branching and arborization of trigeminal axons in the brainstem (Özdinler and Erzurumlu 2002).
T15292 27934-27939 NN denotes Slit2
T15293 27949-27954 VB denotes cause
T15294 27940-27944 VBZ denotes does
T15295 27945-27948 RB denotes not
T15296 27955-27964 NN denotes repulsion
T15297 27965-27967 IN denotes of
T15298 27968-27970 NN denotes NT
T15299 27973-27983 JJ denotes responsive
T15300 27970-27971 HYPH denotes -
T15301 27971-27972 CD denotes 3
T15302 27972-27973 HYPH denotes -
T15303 27988-27993 NNS denotes axons
T15304 27984-27987 NN denotes DRG
T15305 27994-27996 FW denotes in
T15306 27997-28002 FW denotes vitro
T15307 28003-28004 -LRB- denotes (
T15308 28004-28010 NNP denotes Nguyen
T15309 28011-28013 NNP denotes Ba
T15310 28013-28014 HYPH denotes -
T15311 28014-28021 NNP denotes Charvet
T15312 28022-28024 FW denotes et
T15313 28025-28028 FW denotes al.
T15314 28029-28033 CD denotes 2001
T15315 28033-28034 -RRB- denotes )
T15316 28034-28036 , denotes ,
T15317 28036-28039 CC denotes but
T15318 28040-28046 VBZ denotes causes
T15319 28047-28054 JJ denotes ectopic
T15320 28055-28064 NN denotes branching
T15321 28065-28068 CC denotes and
T15322 28069-28081 NN denotes arborization
T15323 28082-28084 IN denotes of
T15324 28085-28095 JJ denotes trigeminal
T15325 28096-28101 NNS denotes axons
T15326 28102-28104 IN denotes in
T15327 28105-28108 DT denotes the
T15328 28109-28118 NN denotes brainstem
T15329 28119-28120 -LRB- denotes (
T15330 28120-28128 NNP denotes Özdinler
T15331 28129-28132 CC denotes and
T15332 28133-28142 NNP denotes Erzurumlu
T15333 28143-28147 CD denotes 2002
T15334 28147-28148 -RRB- denotes )
T15335 28148-28149 . denotes .
T15336 28149-28306 sentence denotes Thus, Slit2 might also be involved in terminal branching of propioceptive axons in the ventral cord and in the midline branching observed in our double KOs.
T15337 28150-28154 RB denotes Thus
T15338 28176-28184 VBN denotes involved
T15339 28154-28156 , denotes ,
T15340 28156-28161 NN denotes Slit2
T15341 28162-28167 MD denotes might
T15342 28168-28172 RB denotes also
T15343 28173-28175 VB denotes be
T15344 28185-28187 IN denotes in
T15345 28188-28196 JJ denotes terminal
T15346 28197-28206 NN denotes branching
T15347 28207-28209 IN denotes of
T15348 28210-28223 JJ denotes propioceptive
T15349 28224-28229 NNS denotes axons
T15350 28230-28232 IN denotes in
T15351 28233-28236 DT denotes the
T15352 28245-28249 NN denotes cord
T15353 28237-28244 JJ denotes ventral
T15354 28250-28253 CC denotes and
T15355 28254-28256 IN denotes in
T15356 28257-28260 DT denotes the
T15357 28269-28278 NN denotes branching
T15358 28261-28268 NN denotes midline
T15359 28279-28287 VBN denotes observed
T15360 28288-28290 IN denotes in
T15361 28291-28294 PRP$ denotes our
T15362 28302-28305 NNS denotes KOs
T15363 28295-28301 JJ denotes double
T15364 28305-28306 . denotes .
T15365 28306-28459 sentence denotes Lack of PV expression in Bax/NT-3 KO mice suggests that PV expression might be responsible for proper axon targeting and muscle spindle differentiation.
T15366 28307-28311 NN denotes Lack
T15367 28349-28357 VBZ denotes suggests
T15368 28312-28314 IN denotes of
T15369 28315-28317 NN denotes PV
T15370 28318-28328 NN denotes expression
T15371 28329-28331 IN denotes in
T15372 28332-28335 NN denotes Bax
T15373 28341-28343 NN denotes KO
T15374 28335-28336 HYPH denotes /
T15375 28336-28338 NN denotes NT
T15376 28338-28339 HYPH denotes -
T15377 28339-28340 CD denotes 3
T15378 28344-28348 NNS denotes mice
T15379 28358-28362 IN denotes that
T15380 28383-28385 VB denotes be
T15381 28363-28365 NN denotes PV
T15382 28366-28376 NN denotes expression
T15383 28377-28382 MD denotes might
T15384 28386-28397 JJ denotes responsible
T15385 28398-28401 IN denotes for
T15386 28402-28408 JJ denotes proper
T15387 28414-28423 NN denotes targeting
T15388 28409-28413 NN denotes axon
T15389 28424-28427 CC denotes and
T15390 28428-28434 NN denotes muscle
T15391 28435-28442 NN denotes spindle
T15392 28443-28458 NN denotes differentiation
T15393 28458-28459 . denotes .
T15394 28459-28517 sentence denotes Presently we cannot completely rule out this possibility.
T15395 28460-28469 RB denotes Presently
T15396 28491-28495 VB denotes rule
T15397 28470-28472 PRP denotes we
T15398 28473-28476 MD denotes can
T15399 28476-28479 RB denotes not
T15400 28480-28490 RB denotes completely
T15401 28496-28499 RP denotes out
T15402 28500-28504 DT denotes this
T15403 28505-28516 NN denotes possibility
T15404 28516-28517 . denotes .
T15405 28517-28775 sentence denotes However, no defects in axon pathfinding along the monosynaptic reflex arc or in muscle spindle differentiation have been noted in PV KO mice, which develop normally and show no apparent changes in their behavior or physical activity (Schwaller et al. 1999).
T15406 28518-28525 RB denotes However
T15407 28639-28644 VBN denotes noted
T15408 28525-28527 , denotes ,
T15409 28527-28529 DT denotes no
T15410 28530-28537 NNS denotes defects
T15411 28538-28540 IN denotes in
T15412 28541-28545 NN denotes axon
T15413 28546-28557 NN denotes pathfinding
T15414 28558-28563 IN denotes along
T15415 28564-28567 DT denotes the
T15416 28588-28591 NN denotes arc
T15417 28568-28580 JJ denotes monosynaptic
T15418 28581-28587 NN denotes reflex
T15419 28592-28594 CC denotes or
T15420 28595-28597 IN denotes in
T15421 28598-28604 NN denotes muscle
T15422 28605-28612 NN denotes spindle
T15423 28613-28628 NN denotes differentiation
T15424 28629-28633 VBP denotes have
T15425 28634-28638 VBN denotes been
T15426 28645-28647 IN denotes in
T15427 28648-28650 NN denotes PV
T15428 28651-28653 NN denotes KO
T15429 28654-28658 NNS denotes mice
T15430 28658-28660 , denotes ,
T15431 28660-28665 WDT denotes which
T15432 28666-28673 VBP denotes develop
T15433 28674-28682 RB denotes normally
T15434 28683-28686 CC denotes and
T15435 28687-28691 VBP denotes show
T15436 28692-28694 DT denotes no
T15437 28704-28711 NNS denotes changes
T15438 28695-28703 JJ denotes apparent
T15439 28712-28714 IN denotes in
T15440 28715-28720 PRP$ denotes their
T15441 28721-28729 NN denotes behavior
T15442 28730-28732 CC denotes or
T15443 28733-28741 JJ denotes physical
T15444 28742-28750 NN denotes activity
T15445 28751-28752 -LRB- denotes (
T15446 28752-28761 NNP denotes Schwaller
T15447 28762-28764 FW denotes et
T15448 28765-28768 FW denotes al.
T15449 28769-28773 CD denotes 1999
T15450 28773-28774 -RRB- denotes )
T15451 28774-28775 . denotes .
T15452 28775-28930 sentence denotes These observations suggest that axonal targeting defects in Bax/NT-3 double KO mice cannot be simply due to lack of PV expression in proprioceptive cells.
T15453 28776-28781 DT denotes These
T15454 28782-28794 NNS denotes observations
T15455 28795-28802 VBP denotes suggest
T15456 28803-28807 IN denotes that
T15457 28867-28869 VB denotes be
T15458 28808-28814 JJ denotes axonal
T15459 28825-28832 NNS denotes defects
T15460 28815-28824 VBG denotes targeting
T15461 28833-28835 IN denotes in
T15462 28836-28839 NN denotes Bax
T15463 28852-28854 NN denotes KO
T15464 28839-28840 HYPH denotes /
T15465 28840-28842 NN denotes NT
T15466 28842-28843 HYPH denotes -
T15467 28843-28844 CD denotes 3
T15468 28845-28851 JJ denotes double
T15469 28855-28859 NNS denotes mice
T15470 28860-28863 MD denotes can
T15471 28863-28866 RB denotes not
T15472 28870-28876 RB denotes simply
T15473 28877-28880 IN denotes due
T15474 28881-28883 IN denotes to
T15475 28884-28888 NN denotes lack
T15476 28889-28891 IN denotes of
T15477 28892-28894 NN denotes PV
T15478 28895-28905 NN denotes expression
T15479 28906-28908 IN denotes in
T15480 28909-28923 JJ denotes proprioceptive
T15481 28924-28929 NNS denotes cells
T15482 28929-28930 . denotes .
T15483 28930-29127 sentence denotes Our present results suggest that NT-3 acts as a short-range axon guidance cue for proprioceptive axons centrally and peripherally, as they navigate to their targets using other axon guidance cues.
T15484 28931-28934 PRP$ denotes Our
T15485 28943-28950 NNS denotes results
T15486 28935-28942 JJ denotes present
T15487 28951-28958 VBP denotes suggest
T15488 28959-28963 IN denotes that
T15489 28969-28973 VBZ denotes acts
T15490 28964-28966 NN denotes NT
T15491 28966-28967 HYPH denotes -
T15492 28967-28968 CD denotes 3
T15493 28974-28976 IN denotes as
T15494 28977-28978 DT denotes a
T15495 29005-29008 NN denotes cue
T15496 28979-28984 JJ denotes short
T15497 28985-28990 NN denotes range
T15498 28984-28985 HYPH denotes -
T15499 28991-28995 NN denotes axon
T15500 28996-29004 NN denotes guidance
T15501 29009-29012 IN denotes for
T15502 29013-29027 JJ denotes proprioceptive
T15503 29028-29033 NNS denotes axons
T15504 29034-29043 RB denotes centrally
T15505 29044-29047 CC denotes and
T15506 29048-29060 RB denotes peripherally
T15507 29060-29062 , denotes ,
T15508 29062-29064 IN denotes as
T15509 29070-29078 VBP denotes navigate
T15510 29065-29069 PRP denotes they
T15511 29079-29081 IN denotes to
T15512 29082-29087 PRP$ denotes their
T15513 29088-29095 NNS denotes targets
T15514 29096-29101 VBG denotes using
T15515 29102-29107 JJ denotes other
T15516 29122-29126 NNS denotes cues
T15517 29108-29112 NN denotes axon
T15518 29113-29121 NN denotes guidance
T15519 29126-29127 . denotes .
T15520 29127-29188 sentence denotes In its absence, these axons terminate in inappropriate loci.
T15521 29128-29130 IN denotes In
T15522 29156-29165 VBP denotes terminate
T15523 29131-29134 PRP$ denotes its
T15524 29135-29142 NN denotes absence
T15525 29142-29144 , denotes ,
T15526 29144-29149 DT denotes these
T15527 29150-29155 NNS denotes axons
T15528 29166-29168 IN denotes in
T15529 29169-29182 JJ denotes inappropriate
T15530 29183-29187 NNS denotes loci
T15531 29187-29188 . denotes .
T15532 29188-29330 sentence denotes However, NT-3 may not be the only molecule that plays a role in targeting and terminal branching of sensory axons in the ventral spinal cord.
T15533 29189-29196 RB denotes However
T15534 29211-29213 VB denotes be
T15535 29196-29198 , denotes ,
T15536 29198-29200 NN denotes NT
T15537 29200-29201 HYPH denotes -
T15538 29201-29202 CD denotes 3
T15539 29203-29206 MD denotes may
T15540 29207-29210 RB denotes not
T15541 29214-29217 DT denotes the
T15542 29223-29231 NN denotes molecule
T15543 29218-29222 JJ denotes only
T15544 29232-29236 WDT denotes that
T15545 29237-29242 VBZ denotes plays
T15546 29243-29244 DT denotes a
T15547 29245-29249 NN denotes role
T15548 29250-29252 IN denotes in
T15549 29253-29262 VBG denotes targeting
T15550 29263-29266 CC denotes and
T15551 29267-29275 JJ denotes terminal
T15552 29276-29285 NN denotes branching
T15553 29286-29288 IN denotes of
T15554 29289-29296 JJ denotes sensory
T15555 29297-29302 NNS denotes axons
T15556 29303-29305 IN denotes in
T15557 29306-29309 DT denotes the
T15558 29325-29329 NN denotes cord
T15559 29310-29317 JJ denotes ventral
T15560 29318-29324 JJ denotes spinal
T15561 29329-29330 . denotes .
T15562 29330-29535 sentence denotes NT-3 most likely acts cooperatively with other axon guidance molecules or by regulating expression of yet to be identified proprioceptive neuron-specific receptors/ligands for numerous axon guidance cues.
T15563 29331-29333 NN denotes NT
T15564 29348-29352 VBZ denotes acts
T15565 29333-29334 HYPH denotes -
T15566 29334-29335 CD denotes 3
T15567 29336-29340 RBS denotes most
T15568 29341-29347 RB denotes likely
T15569 29353-29366 RB denotes cooperatively
T15570 29367-29371 IN denotes with
T15571 29372-29377 JJ denotes other
T15572 29392-29401 NNS denotes molecules
T15573 29378-29382 NN denotes axon
T15574 29383-29391 NN denotes guidance
T15575 29402-29404 CC denotes or
T15576 29405-29407 IN denotes by
T15577 29408-29418 VBG denotes regulating
T15578 29419-29429 NN denotes expression
T15579 29430-29432 IN denotes of
T15580 29433-29436 RB denotes yet
T15581 29443-29453 VBN denotes identified
T15582 29437-29439 TO denotes to
T15583 29440-29442 VB denotes be
T16203 29560-29570 NN denotes Generation
T16204 29571-29573 IN denotes of
T16205 29574-29580 JJ denotes double
T16206 29581-29584 NNS denotes KOs
T16207 29584-29585 . denotes .
T16208 29585-29781 sentence denotes We crossed Bax KO females on a C57BL/6 background (Jackson Laboratory, Bar Harbor, Maine, United States) to NT-3 heterozygote males on a 129 Sv background to generate double heterozygote animals.
T16209 29586-29588 PRP denotes We
T16210 29589-29596 VBD denotes crossed
T16211 29597-29600 NN denotes Bax
T16212 29601-29603 NN denotes KO
T16213 29604-29611 NNS denotes females
T16214 29612-29614 IN denotes on
T16215 29615-29616 DT denotes a
T16216 29625-29635 NN denotes background
T16217 29617-29622 NN denotes C57BL
T16218 29622-29623 HYPH denotes /
T16219 29623-29624 CD denotes 6
T16220 29636-29637 -LRB- denotes (
T16221 29645-29655 NNP denotes Laboratory
T16222 29637-29644 NNP denotes Jackson
T16223 29655-29657 , denotes ,
T16224 29657-29660 NNP denotes Bar
T16225 29661-29667 NNP denotes Harbor
T16226 29667-29669 , denotes ,
T16227 29669-29674 NNP denotes Maine
T16228 29674-29676 , denotes ,
T16229 29676-29682 NNP denotes United
T16230 29683-29689 NNP denotes States
T16231 29689-29690 -RRB- denotes )
T16232 29691-29693 IN denotes to
T16233 29694-29696 NN denotes NT
T16234 29699-29711 NN denotes heterozygote
T16235 29696-29697 HYPH denotes -
T16236 29697-29698 CD denotes 3
T16237 29712-29717 NNS denotes males
T16238 29718-29720 IN denotes on
T16239 29721-29722 DT denotes a
T16240 29730-29740 NN denotes background
T16241 29723-29726 CD denotes 129
T16242 29727-29729 NN denotes Sv
T16243 29741-29743 TO denotes to
T16244 29744-29752 VB denotes generate
T16245 29753-29759 JJ denotes double
T16246 29760-29772 NN denotes heterozygote
T16247 29773-29780 NNS denotes animals
T16248 29780-29781 . denotes .
T16249 29781-29889 sentence denotes Progeny was genotyped with PCR, and animals heterozygous for both genes were bred to obtain the double KOs.
T16250 29782-29789 NN denotes Progeny
T16251 29794-29803 VBN denotes genotyped
T16252 29790-29793 VBD denotes was
T16253 29804-29808 IN denotes with
T16254 29809-29812 NN denotes PCR
T16255 29812-29814 , denotes ,
T16256 29814-29817 CC denotes and
T16257 29818-29825 NNS denotes animals
T16258 29859-29863 VBN denotes bred
T16259 29826-29838 JJ denotes heterozygous
T16260 29839-29842 IN denotes for
T16261 29843-29847 DT denotes both
T16262 29848-29853 NNS denotes genes
T16263 29854-29858 VBD denotes were
T16264 29864-29866 TO denotes to
T16265 29867-29873 VB denotes obtain
T16266 29874-29877 DT denotes the
T16267 29885-29888 NNS denotes KOs
T16268 29878-29884 JJ denotes double
T16269 29888-29889 . denotes .
T16270 29889-30032 sentence denotes Primers used for the Bax locus were R661, GTT GAC CAG AGT GGC GTA GG; R662, CCG CTT CCA TTG CTC AGC GG; and R663, GAG CTG ATC AGA ACC ATC ATG.
T16271 29890-29897 NNS denotes Primers
T16272 29921-29925 VBD denotes were
T16273 29898-29902 VBN denotes used
T16274 29903-29906 IN denotes for
T16275 29907-29910 DT denotes the
T16276 29915-29920 NN denotes locus
T16277 29911-29914 NN denotes Bax
T16278 29926-29930 NN denotes R661
T16279 29930-29932 , denotes ,
T16280 29932-29935 NN denotes GTT
T16281 29956-29958 NN denotes GG
T16282 29936-29939 NN denotes GAC
T16283 29940-29943 NN denotes CAG
T16284 29944-29947 NN denotes AGT
T16285 29948-29951 NN denotes GGC
T16286 29952-29955 NN denotes GTA
T16287 29958-29959 : denotes ;
T16288 29960-29964 NN denotes R662
T16289 29964-29966 , denotes ,
T16290 29966-29969 NN denotes CCG
T16291 29990-29992 NN denotes GG
T16292 29970-29973 NN denotes CTT
T16293 29974-29977 NN denotes CCA
T16294 29978-29981 NN denotes TTG
T16295 29982-29985 NN denotes CTC
T16296 29986-29989 NN denotes AGC
T16297 29992-29993 : denotes ;
T16298 29994-29997 CC denotes and
T16299 29998-30002 NN denotes R663
T16300 30002-30004 , denotes ,
T16301 30004-30007 NN denotes GAG
T16302 30028-30031 NN denotes ATG
T16303 30008-30011 NN denotes CTG
T16304 30012-30015 NN denotes ATC
T16305 30016-30019 NN denotes AGA
T16306 30020-30023 NN denotes ACC
T16307 30024-30027 NN denotes ATC
T16308 30031-30032 . denotes .
T16309 30032-30215 sentence denotes Primers used for the NT-3 locus were NT3A, CGT GGT GAG GTT CTA TTG GCT AC; NT3B, CAG AGC ACC CTG CCC AAA GCA GAG; NT3R, CCT TGA CAA TAC TGA ATG CC; and NEOF, GGG AAC TTC CTG ACT AGG.
T16310 30033-30040 NNS denotes Primers
T16311 30065-30069 VBD denotes were
T16312 30041-30045 VBN denotes used
T16313 30046-30049 IN denotes for
T16314 30050-30053 DT denotes the
T16315 30059-30064 NN denotes locus
T16316 30054-30056 NN denotes NT
T16317 30056-30057 HYPH denotes -
T16318 30057-30058 CD denotes 3
T16319 30070-30074 NN denotes NT3A
T16320 30074-30076 , denotes ,
T16321 30076-30079 NN denotes CGT
T16322 30104-30106 NN denotes AC
T16323 30080-30083 NN denotes GGT
T16324 30084-30087 NN denotes GAG
T16325 30088-30091 NN denotes GTT
T16326 30092-30095 NN denotes CTA
T16327 30096-30099 NN denotes TTG
T16328 30100-30103 NN denotes GCT
T16329 30106-30107 : denotes ;
T16330 30108-30112 NN denotes NT3B
T16331 30112-30114 , denotes ,
T16332 30114-30117 NN denotes CAG
T16333 30142-30145 NN denotes GAG
T16334 30118-30121 NN denotes AGC
T16335 30122-30125 NN denotes ACC
T16336 30126-30129 NN denotes CTG
T16337 30130-30133 NN denotes CCC
T16338 30134-30137 NN denotes AAA
T16339 30138-30141 NN denotes GCA
T16340 30145-30146 : denotes ;
T16341 30147-30151 NN denotes NT3R
T16342 30151-30153 , denotes ,
T16343 30153-30156 NN denotes CCT
T16344 30177-30179 NN denotes CC
T16345 30157-30160 NN denotes TGA
T16346 30161-30164 NN denotes CAA
T16347 30165-30168 NN denotes TAC
T16348 30169-30172 NN denotes TGA
T16349 30173-30176 NN denotes ATG
T16350 30179-30180 : denotes ;
T16351 30181-30184 CC denotes and
T16352 30185-30189 NN denotes NEOF
T16353 30189-30191 , denotes ,
T16354 30191-30194 NN denotes GGG
T16355 30211-30214 NN denotes AGG
T16356 30195-30198 NN denotes AAC
T16357 30199-30202 NN denotes TTC
T16358 30203-30206 NN denotes CTG
T16359 30207-30210 NN denotes ACT
T16360 30214-30215 . denotes .
T16361 30215-30274 sentence denotes WT, Bax KO, and NT-3 KO littermates were used as controls.
T16362 30216-30218 NN denotes WT
T16363 30240-30251 NNS denotes littermates
T16364 30218-30220 , denotes ,
T16365 30220-30223 NN denotes Bax
T16366 30224-30226 NN denotes KO
T16367 30226-30228 , denotes ,
T16368 30228-30231 CC denotes and
T16369 30232-30234 NN denotes NT
T16370 30237-30239 NN denotes KO
T16371 30234-30235 HYPH denotes -
T16372 30235-30236 CD denotes 3
T16373 30257-30261 VBN denotes used
T16374 30252-30256 VBD denotes were
T16375 30262-30264 IN denotes as
T16376 30265-30273 NNS denotes controls
T16377 30273-30274 . denotes .
T16378 30274-30355 sentence denotes A total of 11 Bax/NT-3 double KO mice were analyzed, of these nine were P0 pups.
T16379 30275-30276 DT denotes A
T16380 30277-30282 NN denotes total
T16381 30318-30326 VBN denotes analyzed
T16382 30283-30285 IN denotes of
T16383 30286-30288 CD denotes 11
T16384 30308-30312 NNS denotes mice
T16385 30289-30292 NN denotes Bax
T16386 30305-30307 NN denotes KO
T16387 30292-30293 HYPH denotes /
T16388 30293-30295 NN denotes NT
T16389 30295-30296 HYPH denotes -
T16390 30296-30297 CD denotes 3
T16391 30298-30304 JJ denotes double
T16392 30313-30317 VBD denotes were
T16393 30342-30346 VBD denotes were
T16394 30326-30328 , denotes ,
T16395 30328-30330 IN denotes of
T16396 30331-30336 DT denotes these
T16397 30337-30341 CD denotes nine
T16398 30347-30349 NN denotes P0
T16399 30350-30354 NNS denotes pups
T16400 30354-30355 . denotes .
T16401 30355-30431 sentence denotes The p75 colony on a 129 S1 background was received from Jackson Laboratory.
T16402 30356-30359 DT denotes The
T16403 30364-30370 NN denotes colony
T16404 30360-30363 NN denotes p75
T16405 30398-30406 VBN denotes received
T16406 30371-30373 IN denotes on
T16407 30374-30375 DT denotes a
T16408 30383-30393 NN denotes background
T16409 30376-30379 CD denotes 129
T16410 30380-30382 NN denotes S1
T16411 30394-30397 VBD denotes was
T16412 30407-30411 IN denotes from
T16413 30412-30419 NNP denotes Jackson
T16414 30420-30430 NNP denotes Laboratory
T16415 30430-30431 . denotes .
T16416 30431-30677 sentence denotes We used tail DNA to genotype animals using the primers IMR0013, CTT GGG TGG AGA GGC TAT TC; IMR0014, AGG TGA GAT GAC AGG AGA TC (generic neo primers); IMR0710, TGT TAC GTT CTC TGA CGT GGT GAG; and IMR0711, TCA GCC CAG GGT GTG CAC TC (p75 locus).
T16417 30432-30434 PRP denotes We
T16418 30435-30439 VBD denotes used
T16419 30440-30444 NN denotes tail
T16420 30445-30448 NN denotes DNA
T16421 30449-30451 TO denotes to
T16422 30452-30460 VB denotes genotype
T16423 30461-30468 NNS denotes animals
T16424 30469-30474 VBG denotes using
T16425 30475-30478 DT denotes the
T16426 30479-30486 NNS denotes primers
T16427 30487-30494 NN denotes IMR0013
T16428 30494-30496 , denotes ,
T16429 30496-30499 NN denotes CTT
T16430 30520-30522 NN denotes TC
T16431 30500-30503 NN denotes GGG
T16432 30504-30507 NN denotes TGG
T16433 30508-30511 NN denotes AGA
T16434 30512-30515 NN denotes GGC
T16435 30516-30519 NN denotes TAT
T16436 30522-30523 : denotes ;
T16437 30524-30531 NN denotes IMR0014
T16438 30531-30533 , denotes ,
T16439 30533-30536 NN denotes AGG
T16440 30557-30559 NN denotes TC
T16441 30537-30540 NN denotes TGA
T16442 30541-30544 NN denotes GAT
T16443 30545-30548 NN denotes GAC
T16444 30549-30552 NN denotes AGG
T16445 30553-30556 NN denotes AGA
T16446 30560-30561 -LRB- denotes (
T16447 30561-30568 JJ denotes generic
T16448 30573-30580 NNS denotes primers
T16449 30569-30572 NN denotes neo
T16450 30580-30581 -RRB- denotes )
T16451 30581-30582 : denotes ;
T16452 30583-30590 NN denotes IMR0710
T16453 30590-30592 , denotes ,
T16454 30592-30595 NN denotes TGT
T16455 30620-30623 NN denotes GAG
T16456 30596-30599 NN denotes TAC
T16457 30600-30603 NN denotes GTT
T16458 30604-30607 NN denotes CTC
T16459 30608-30611 NN denotes TGA
T16460 30612-30615 NN denotes CGT
T16461 30616-30619 NN denotes GGT
T16462 30623-30624 : denotes ;
T16463 30625-30628 CC denotes and
T16464 30629-30636 NN denotes IMR0711
T16465 30636-30638 , denotes ,
T16466 30638-30641 NN denotes TCA
T16467 30662-30664 NN denotes TC
T16468 30642-30645 NN denotes GCC
T16469 30646-30649 NN denotes CAG
T16470 30650-30653 NN denotes GGT
T16471 30654-30657 NN denotes GTG
T16472 30658-30661 NN denotes CAC
T16473 30665-30666 -LRB- denotes (
T16474 30670-30675 NN denotes locus
T16475 30666-30669 NN denotes p75
T16476 30675-30676 -RRB- denotes )
T16477 30676-30677 . denotes .
T16478 30677-30746 sentence denotes For embryonic experiments, day of plug positivity was considered E0.
T16479 30678-30681 IN denotes For
T16480 30732-30742 VBN denotes considered
T16481 30682-30691 JJ denotes embryonic
T16482 30692-30703 NNS denotes experiments
T16483 30703-30705 , denotes ,
T16484 30705-30708 NN denotes day
T16485 30709-30711 IN denotes of
T16486 30712-30716 NN denotes plug
T16487 30717-30727 NN denotes positivity
T16488 30728-30731 VBD denotes was
T16489 30743-30745 NN denotes E0
T16490 30745-30746 . denotes .
T16491 30746-30996 sentence denotes All of the protocols used in this study were approved by the Louisiana State University Health Sciences Center Institutional Animal Care and Use Committee and conformed to the National Institutes of Health guidelines for use of experimental animals.
T16492 30747-30750 DT denotes All
T16493 30792-30800 VBN denotes approved
T16494 30751-30753 IN denotes of
T16495 30754-30757 DT denotes the
T16496 30758-30767 NNS denotes protocols
T16497 30768-30772 VBN denotes used
T16498 30773-30775 IN denotes in
T16499 30776-30780 DT denotes this
T16500 30781-30786 NN denotes study
T16501 30787-30791 VBD denotes were
T16502 30801-30803 IN denotes by
T16503 30804-30807 DT denotes the
T16504 30892-30901 NNP denotes Committee
T16505 30808-30817 NNP denotes Louisiana
T16506 30824-30834 NNP denotes University
T16507 30818-30823 NNP denotes State
T16508 30851-30857 NNP denotes Center
T16509 30835-30841 NNP denotes Health
T16510 30842-30850 NNPS denotes Sciences
T16511 30858-30871 NNP denotes Institutional
T16512 30872-30878 NNP denotes Animal
T16513 30879-30883 NNP denotes Care
T16514 30884-30887 CC denotes and
T16515 30888-30891 NNP denotes Use
T16516 30902-30905 CC denotes and
T16517 30906-30915 VBD denotes conformed
T16518 30916-30918 IN denotes to
T16519 30919-30922 DT denotes the
T16520 30953-30963 NNS denotes guidelines
T16521 30923-30931 NNP denotes National
T16522 30932-30942 NNPS denotes Institutes
T16523 30943-30945 IN denotes of
T16524 30946-30952 NNP denotes Health
T16525 30964-30967 IN denotes for
T16526 30968-30971 NN denotes use
T16527 30972-30974 IN denotes of
T16528 30975-30987 JJ denotes experimental
T16529 30988-30995 NNS denotes animals
T16530 30995-30996 . denotes .
T16880 30998-31002 NN denotes TrkA
T16881 31003-31007 NN denotes TrkC
T16882 31002-31003 HYPH denotes /
T16883 31008-31028 NN denotes immunohistochemistry
T16884 31028-31029 . denotes .
T16885 31029-31427 sentence denotes Frozen spinal cord sections (10 μm thick) were blocked and incubated in a cocktail of rabbit anti-TrkA and goat anti-TrkC antibodies (gift of Dr. Reichardt; Huang et al. 1999), followed by a cocktail of CY3 conjugated donkey anti-rabbit and FITC conjugated donkey anti-goat antibodies (Chemicon, Temecula, California, United States) in the presence of 0.3% TritonX-100 and 10% normal donkey serum.
T16886 31030-31036 JJ denotes Frozen
T16887 31049-31057 NNS denotes sections
T16888 31037-31043 JJ denotes spinal
T16889 31044-31048 NN denotes cord
T16890 31077-31084 VBN denotes blocked
T16891 31058-31059 -LRB- denotes (
T16892 31059-31061 CD denotes 10
T16893 31062-31064 NN denotes μm
T16894 31065-31070 JJ denotes thick
T16895 31070-31071 -RRB- denotes )
T16896 31072-31076 VBD denotes were
T16897 31085-31088 CC denotes and
T16898 31089-31098 VBN denotes incubated
T16899 31099-31101 IN denotes in
T16900 31102-31103 DT denotes a
T16901 31104-31112 NN denotes cocktail
T16902 31113-31115 IN denotes of
T16903 31116-31122 NN denotes rabbit
T16904 31123-31132 JJ denotes anti-TrkA
T16905 31133-31136 CC denotes and
T16906 31137-31141 NN denotes goat
T16907 31152-31162 NNS denotes antibodies
T16908 31142-31151 JJ denotes anti-TrkC
T16909 31163-31164 -LRB- denotes (
T16910 31164-31168 NN denotes gift
T16911 31169-31171 IN denotes of
T16912 31172-31175 NNP denotes Dr.
T16913 31176-31185 NNP denotes Reichardt
T16914 31185-31186 : denotes ;
T16915 31187-31192 NNP denotes Huang
T16916 31193-31195 FW denotes et
T16917 31196-31199 FW denotes al.
T16918 31200-31204 CD denotes 1999
T16919 31204-31205 -RRB- denotes )
T16920 31205-31207 , denotes ,
T16921 31207-31215 VBN denotes followed
T16922 31216-31218 IN denotes by
T16923 31219-31220 DT denotes a
T16924 31221-31229 NN denotes cocktail
T16925 31230-31232 IN denotes of
T16926 31233-31236 NN denotes CY3
T16927 31237-31247 VBN denotes conjugated
T16928 31248-31254 NN denotes donkey
T16929 31255-31266 JJ denotes anti-rabbit
T16930 31267-31270 CC denotes and
T16931 31271-31275 NN denotes FITC
T16932 31276-31286 VBN denotes conjugated
T16933 31287-31293 NN denotes donkey
T16934 31304-31314 NNS denotes antibodies
T16935 31294-31303 JJ denotes anti-goat
T16936 31315-31316 -LRB- denotes (
T16937 31316-31324 NNP denotes Chemicon
T16938 31324-31326 , denotes ,
T16939 31326-31334 NNP denotes Temecula
T16940 31334-31336 , denotes ,
T16941 31336-31346 NNP denotes California
T16942 31346-31348 , denotes ,
T16943 31348-31354 NNP denotes United
T16944 31355-31361 NNP denotes States
T16945 31361-31362 -RRB- denotes )
T16946 31363-31365 IN denotes in
T16947 31366-31369 DT denotes the
T16948 31370-31378 NN denotes presence
T16949 31379-31381 IN denotes of
T16950 31382-31385 CD denotes 0.3
T16951 31385-31386 NN denotes %
T16952 31387-31394 NN denotes TritonX
T16953 31394-31395 HYPH denotes -
T16954 31395-31398 CD denotes 100
T16955 31399-31402 CC denotes and
T16956 31403-31405 CD denotes 10
T16957 31405-31406 NN denotes %
T16958 31421-31426 NN denotes serum
T16959 31407-31413 JJ denotes normal
T16960 31414-31420 NN denotes donkey
T16961 31426-31427 . denotes .
T16962 31427-31679 sentence denotes For PV immunohistochemistry, sections were reacted with monoclonal mouse anti-PV antibody (Sigma, St. Louis, Missouri, United States), and developed by Vector fluorescein mouse on mouse kit (Vector Laboratories, Burlingame, California, United States).
T16963 31428-31431 IN denotes For
T16964 31471-31478 VBN denotes reacted
T16965 31432-31434 NN denotes PV
T16966 31435-31455 NN denotes immunohistochemistry
T16967 31455-31457 , denotes ,
T16968 31457-31465 NNS denotes sections
T16969 31466-31470 VBD denotes were
T16970 31479-31483 IN denotes with
T16971 31484-31494 JJ denotes monoclonal
T16972 31509-31517 NN denotes antibody
T16973 31495-31500 NN denotes mouse
T16974 31501-31508 JJ denotes anti-PV
T16975 31518-31519 -LRB- denotes (
T16976 31519-31524 NNP denotes Sigma
T16977 31524-31526 , denotes ,
T16978 31526-31529 NNP denotes St.
T16979 31530-31535 NNP denotes Louis
T16980 31535-31537 , denotes ,
T16981 31537-31545 NNP denotes Missouri
T16982 31545-31547 , denotes ,
T16983 31547-31553 NNP denotes United
T16984 31554-31560 NNP denotes States
T16985 31560-31561 -RRB- denotes )
T16986 31561-31563 , denotes ,
T16987 31563-31566 CC denotes and
T16988 31567-31576 VBN denotes developed
T16989 31577-31579 IN denotes by
T16990 31580-31586 NNP denotes Vector
T16991 31587-31598 NN denotes fluorescein
T16992 31614-31617 NN denotes kit
T16993 31599-31604 NN denotes mouse
T16994 31605-31607 IN denotes on
T16995 31608-31613 NN denotes mouse
T16996 31618-31619 -LRB- denotes (
T16997 31626-31638 NNP denotes Laboratories
T16998 31619-31625 NNP denotes Vector
T16999 31638-31640 , denotes ,
T17000 31640-31650 NNP denotes Burlingame
T17001 31650-31652 , denotes ,
T17002 31652-31662 NNP denotes California
T17003 31662-31664 , denotes ,
T17004 31664-31670 NNP denotes United
T17005 31671-31677 NNP denotes States
T17006 31677-31678 -RRB- denotes )
T17007 31678-31679 . denotes .
T17008 31679-31829 sentence denotes For quantification purposes, TrkA- and TrkC-labeled cells from four different DRGs of each genotype and age studied were counted, and ratios plotted.
T17009 31680-31683 IN denotes For
T17010 31801-31808 VBN denotes counted
T17011 31684-31698 NN denotes quantification
T17012 31699-31707 NNS denotes purposes
T17013 31707-31709 , denotes ,
T17014 31709-31713 NN denotes TrkA
T17015 31724-31731 VBN denotes labeled
T17016 31713-31714 HYPH denotes -
T17017 31715-31718 CC denotes and
T17018 31719-31723 NN denotes TrkC
T17019 31723-31724 HYPH denotes -
T17020 31732-31737 NNS denotes cells
T17021 31738-31742 IN denotes from
T17022 31743-31747 CD denotes four
T17023 31758-31762 NNS denotes DRGs
T17024 31748-31757 JJ denotes different
T17025 31763-31765 IN denotes of
T17026 31766-31770 DT denotes each
T17027 31771-31779 NN denotes genotype
T17028 31780-31783 CC denotes and
T17029 31784-31787 NN denotes age
T17030 31788-31795 VBN denotes studied
T17031 31796-31800 VBD denotes were
T17032 31808-31810 , denotes ,
T17033 31810-31813 CC denotes and
T17034 31814-31820 NNS denotes ratios
T17035 31821-31828 VBN denotes plotted
T17036 31828-31829 . denotes .
T17352 31831-31837 NN denotes Muscle
T17353 31838-31845 NN denotes spindle
T17354 31846-31855 NN denotes detection
T17355 31855-31856 . denotes .
T17356 31856-32056 sentence denotes Gastrocnemius muscle was dissected out in P0 pups and sectioned longitudinally, or, in some cases, the whole leg at the level of gastrocnemius muscle with tibial nerve was sectioned in cross section.
T17357 31857-31870 NN denotes Gastrocnemius
T17358 31871-31877 NN denotes muscle
T17359 31882-31891 VBN denotes dissected
T17360 31878-31881 VBD denotes was
T17361 31892-31895 RP denotes out
T17362 31896-31898 IN denotes in
T17363 31899-31901 NN denotes P0
T17364 31902-31906 NNS denotes pups
T17365 31907-31910 CC denotes and
T17366 31911-31920 VBN denotes sectioned
T17367 31921-31935 RB denotes longitudinally
T17368 31935-31937 , denotes ,
T17369 31937-31939 CC denotes or
T17370 31939-31941 , denotes ,
T17371 31941-31943 IN denotes in
T17372 32029-32038 VBN denotes sectioned
T17373 31944-31948 DT denotes some
T17374 31949-31954 NNS denotes cases
T17375 31954-31956 , denotes ,
T17376 31956-31959 DT denotes the
T17377 31966-31969 NN denotes leg
T17378 31960-31965 JJ denotes whole
T17379 31970-31972 IN denotes at
T17380 31973-31976 DT denotes the
T17381 31977-31982 NN denotes level
T17382 31983-31985 IN denotes of
T17383 31986-31999 NN denotes gastrocnemius
T17384 32000-32006 NN denotes muscle
T17385 32007-32011 IN denotes with
T17386 32012-32018 JJ denotes tibial
T17387 32019-32024 NN denotes nerve
T17388 32025-32028 VBD denotes was
T17389 32039-32041 IN denotes in
T17390 32042-32047 NN denotes cross
T17391 32048-32055 NN denotes section
T17392 32055-32056 . denotes .
T17393 32056-32414 sentence denotes Sections were incubated with monoclonal S46 antibody (gift of Dr. Stockdale) reactive to the spindle-specific slow-tonic myosin heavy chain isoform and developed by Vector mouse on mouse kit as described above, followed by rabbit anti-NF-M antibody (Chemicon) and CY3 conjugated goat anti-rabbit antibody (Chemicon) in a sequential double-labeling protocol.
T17394 32057-32065 NNS denotes Sections
T17395 32071-32080 VBN denotes incubated
T17396 32066-32070 VBD denotes were
T17397 32081-32085 IN denotes with
T17398 32086-32096 JJ denotes monoclonal
T17399 32101-32109 NN denotes antibody
T17400 32097-32100 NN denotes S46
T17401 32110-32111 -LRB- denotes (
T17402 32111-32115 NN denotes gift
T17403 32116-32118 IN denotes of
T17404 32119-32122 NNP denotes Dr.
T17405 32123-32132 NNP denotes Stockdale
T17406 32132-32133 -RRB- denotes )
T17407 32134-32142 JJ denotes reactive
T17408 32143-32145 IN denotes to
T17409 32146-32149 DT denotes the
T17410 32197-32204 NN denotes isoform
T17411 32150-32157 NN denotes spindle
T17412 32158-32166 JJ denotes specific
T17413 32157-32158 HYPH denotes -
T17414 32167-32171 JJ denotes slow
T17415 32172-32177 NN denotes tonic
T17416 32171-32172 HYPH denotes -
T17417 32178-32184 NN denotes myosin
T17418 32185-32190 JJ denotes heavy
T17419 32191-32196 NN denotes chain
T17420 32205-32208 CC denotes and
T17421 32209-32218 VBN denotes developed
T17422 32219-32221 IN denotes by
T17423 32222-32228 NNP denotes Vector
T17424 32244-32247 NN denotes kit
T17425 32229-32234 NN denotes mouse
T17426 32235-32237 IN denotes on
T17427 32238-32243 NN denotes mouse
T17428 32248-32250 IN denotes as
T17429 32251-32260 VBN denotes described
T17430 32261-32266 RB denotes above
T17431 32266-32268 , denotes ,
T17432 32268-32276 VBN denotes followed
T17433 32277-32279 IN denotes by
T17434 32280-32286 NN denotes rabbit
T17435 32297-32305 NN denotes antibody
T17436 32287-32294 JJ denotes anti-NF
T17437 32295-32296 NN denotes M
T17438 32294-32295 HYPH denotes -
T17439 32306-32307 -LRB- denotes (
T17440 32307-32315 NNP denotes Chemicon
T17441 32315-32316 -RRB- denotes )
T17442 32317-32320 CC denotes and
T17443 32321-32324 NN denotes CY3
T17444 32353-32361 NN denotes antibody
T17445 32325-32335 VBN denotes conjugated
T17446 32336-32340 NN denotes goat
T17447 32341-32352 JJ denotes anti-rabbit
T17448 32362-32363 -LRB- denotes (
T17449 32363-32371 NNP denotes Chemicon
T17450 32371-32372 -RRB- denotes )
T17451 32373-32375 IN denotes in
T17452 32376-32377 DT denotes a
T17453 32405-32413 NN denotes protocol
T17454 32378-32388 JJ denotes sequential
T17455 32389-32395 JJ denotes double
T17456 32396-32404 NN denotes labeling
T17457 32395-32396 HYPH denotes -
T17458 32413-32414 . denotes .
T17459 32414-32611 sentence denotes In another method, DiI crystals were placed in DRGs of E17 embryos from different genotypes (n = 2), and the gastrocnemius muscle was isolated and sectioned into 40-μm-thick slices on a vibratome.
T17460 32415-32417 IN denotes In
T17461 32452-32458 VBN denotes placed
T17462 32418-32425 DT denotes another
T17463 32426-32432 NN denotes method
T17464 32432-32434 , denotes ,
T17465 32434-32437 NN denotes DiI
T17466 32438-32446 NNS denotes crystals
T17467 32447-32451 VBD denotes were
T17468 32459-32461 IN denotes in
T17469 32462-32466 NNS denotes DRGs
T17470 32467-32469 IN denotes of
T17471 32470-32473 NN denotes E17
T17472 32474-32481 NNS denotes embryos
T17473 32482-32486 IN denotes from
T17474 32487-32496 JJ denotes different
T17475 32497-32506 NNS denotes genotypes
T17476 32507-32508 -LRB- denotes (
T17477 32512-32513 CD denotes 2
T17478 32508-32509 NN denotes n
T17479 32510-32511 SYM denotes =
T17480 32513-32514 -RRB- denotes )
T17481 32514-32516 , denotes ,
T17482 32516-32519 CC denotes and
T17483 32520-32523 DT denotes the
T17484 32538-32544 NN denotes muscle
T17485 32524-32537 NN denotes gastrocnemius
T17486 32549-32557 VBN denotes isolated
T17487 32545-32548 VBD denotes was
T17488 32558-32561 CC denotes and
T17489 32562-32571 VBN denotes sectioned
T17490 32572-32576 IN denotes into
T17491 32577-32579 CD denotes 40
T17492 32580-32582 NN denotes μm
T17493 32579-32580 HYPH denotes -
T17494 32583-32588 JJ denotes thick
T17495 32582-32583 HYPH denotes -
T17496 32589-32595 NNS denotes slices
T17497 32596-32598 IN denotes on
T17498 32599-32600 DT denotes a
T17499 32601-32610 NN denotes vibratome
T17500 32610-32611 . denotes .
T17771 32613-32616 NN denotes DiI
T17772 32617-32625 NN denotes labeling
T17773 32625-32626 . denotes .
T17774 32626-32903 sentence denotes Spinal cords were dissected out with the DRGs attached, motor root was cut to prevent backfilling of motor neurons, and crystals of 1,1′-dioctadecyl-3,3,3′,3′-tetramethylindocarbocyanine perchlorate (DiI; Molecular Probes, Eugene, Oregon, United States) were inserted in DRGs.
T17775 32627-32633 JJ denotes Spinal
T17776 32634-32639 NNS denotes cords
T17777 32645-32654 VBN denotes dissected
T17778 32640-32644 VBD denotes were
T17779 32655-32658 RP denotes out
T17780 32659-32663 IN denotes with
T17781 32673-32681 VBN denotes attached
T17782 32664-32667 DT denotes the
T17783 32668-32672 NNS denotes DRGs
T17784 32681-32683 , denotes ,
T17785 32683-32688 NN denotes motor
T17786 32689-32693 NN denotes root
T17787 32698-32701 VBN denotes cut
T17788 32694-32697 VBD denotes was
T17789 32702-32704 TO denotes to
T17790 32705-32712 VB denotes prevent
T17791 32713-32724 NN denotes backfilling
T17792 32725-32727 IN denotes of
T17793 32728-32733 NN denotes motor
T17794 32734-32741 NNS denotes neurons
T17795 32741-32743 , denotes ,
T17796 32743-32746 CC denotes and
T17797 32747-32755 NNS denotes crystals
T17798 32886-32894 VBN denotes inserted
T17799 32756-32758 IN denotes of
T17800 32759-32760 CD denotes 1
T17801 32814-32825 NN denotes perchlorate
T17802 32760-32761 , denotes ,
T17803 32761-32762 CD denotes 1
T17804 32762-32763 SYM denotes ′
T17805 32763-32764 HYPH denotes -
T17806 32764-32775 NN denotes dioctadecyl
T17807 32775-32776 HYPH denotes -
T17808 32776-32777 CD denotes 3
T17809 32777-32778 , denotes ,
T17810 32778-32779 CD denotes 3
T17811 32779-32780 , denotes ,
T17812 32780-32781 CD denotes 3
T17813 32781-32782 SYM denotes ′
T17814 32782-32783 , denotes ,
T17815 32783-32784 CD denotes 3
T17816 32784-32785 SYM denotes ′
T17817 32785-32786 HYPH denotes -
T17818 32786-32813 NN denotes tetramethylindocarbocyanine
T17819 32826-32827 -LRB- denotes (
T17820 32842-32848 NNP denotes Probes
T17821 32827-32830 NN denotes DiI
T17822 32830-32831 : denotes ;
T17823 32832-32841 NNP denotes Molecular
T17824 32848-32850 , denotes ,
T17825 32850-32856 NNP denotes Eugene
T17826 32856-32858 , denotes ,
T17827 32858-32864 NNP denotes Oregon
T17828 32864-32866 , denotes ,
T17829 32866-32872 NNP denotes United
T17830 32873-32879 NNP denotes States
T17831 32879-32880 -RRB- denotes )
T17832 32881-32885 VBD denotes were
T17833 32895-32897 IN denotes in
T17834 32898-32902 NNS denotes DRGs
T17835 32902-32903 . denotes .
T17836 32903-32996 sentence denotes Labeled spinal cords were incubated at 37 °C for 8 d and sectioned on a vibrotome at 100 μm.
T17837 32904-32911 VBN denotes Labeled
T17838 32919-32924 NNS denotes cords
T17839 32912-32918 JJ denotes spinal
T17840 32930-32939 VBN denotes incubated
T17841 32925-32929 VBD denotes were
T17842 32940-32942 IN denotes at
T17843 32943-32945 CD denotes 37
T17844 32946-32948 NN denotes °C
T17845 32949-32952 IN denotes for
T17846 32953-32954 CD denotes 8
T17847 32955-32956 NN denotes d
T17848 32957-32960 CC denotes and
T17849 32961-32970 VBN denotes sectioned
T17850 32971-32973 IN denotes on
T17851 32974-32975 DT denotes a
T17852 32976-32985 NN denotes vibrotome
T17853 32986-32988 IN denotes at
T17854 32989-32992 CD denotes 100
T17855 32993-32995 NN denotes μm
T17856 32995-32996 . denotes .
T17857 32996-33170 sentence denotes Sections were observed under the fluorescent microscope and photographed, and images were transferred to Adobe Photoshop, inverted, and adjusted for brightness and contrast.
T17858 32997-33005 NNS denotes Sections
T17859 33011-33019 VBN denotes observed
T17860 33006-33010 VBD denotes were
T17861 33020-33025 IN denotes under
T17862 33026-33029 DT denotes the
T17863 33042-33052 NN denotes microscope
T17864 33030-33041 JJ denotes fluorescent
T17865 33053-33056 CC denotes and
T17866 33057-33069 VBN denotes photographed
T17867 33069-33071 , denotes ,
T17868 33071-33074 CC denotes and
T17869 33075-33081 NNS denotes images
T17870 33087-33098 VBN denotes transferred
T17871 33082-33086 VBD denotes were
T17872 33099-33101 IN denotes to
T17873 33102-33107 NNP denotes Adobe
T17874 33108-33117 NNP denotes Photoshop
T17875 33117-33119 , denotes ,
T17876 33119-33127 VBN denotes inverted
T17877 33127-33129 , denotes ,
T17878 33129-33132 CC denotes and
T17879 33133-33141 VBN denotes adjusted
T17880 33142-33145 IN denotes for
T17881 33146-33156 NN denotes brightness
T17882 33157-33160 CC denotes and
T17883 33161-33169 NN denotes contrast
T17884 33169-33170 . denotes .
T17885 33170-33259 sentence denotes Photoconverted in 0.15% DAB (3,3′-diaminobenzidine; Sigma) in 0.1M Tris buffer (pH 8.2).
T17886 33171-33185 VBN denotes Photoconverted
T17887 33186-33188 IN denotes in
T17888 33189-33193 CD denotes 0.15
T17889 33193-33194 NN denotes %
T17890 33195-33198 NN denotes DAB
T17891 33199-33200 -LRB- denotes (
T17892 33223-33228 NNP denotes Sigma
T17893 33200-33201 CD denotes 3
T17894 33205-33221 NN denotes diaminobenzidine
T17895 33201-33202 , denotes ,
T17896 33202-33203 CD denotes 3
T17897 33203-33204 SYM denotes ′
T17898 33204-33205 HYPH denotes -
T17899 33221-33222 : denotes ;
T17900 33228-33229 -RRB- denotes )
T17901 33230-33232 IN denotes in
T17902 33233-33236 CD denotes 0.1
T17903 33236-33237 NN denotes M
T17904 33243-33249 NN denotes buffer
T17905 33238-33242 NN denotes Tris
T17906 33250-33251 -LRB- denotes (
T17907 33251-33253 NN denotes pH
T17908 33254-33257 CD denotes 8.2
T17909 33257-33258 -RRB- denotes )
T17910 33258-33259 . denotes .
T18468 33261-33263 FW denotes In
T18469 33264-33269 FW denotes vitro
T18470 33281-33286 NN denotes assay
T18471 33270-33280 NN denotes co-culture
T18472 33286-33287 . denotes .
T18473 33287-33377 sentence denotes DRG explants were derived from Swiss Webster, Bax null, and p75 null mouse embryos (E13).
T18474 33288-33291 NN denotes DRG
T18475 33292-33300 NNS denotes explants
T18476 33306-33313 VBN denotes derived
T18477 33301-33305 VBD denotes were
T18478 33314-33318 IN denotes from
T18479 33319-33324 NNP denotes Swiss
T18480 33325-33332 NNP denotes Webster
T18481 33363-33370 NNS denotes embryos
T18482 33332-33334 , denotes ,
T18483 33334-33337 NNP denotes Bax
T18484 33338-33342 JJ denotes null
T18485 33342-33344 , denotes ,
T18486 33344-33347 CC denotes and
T18487 33348-33351 NN denotes p75
T18488 33352-33356 JJ denotes null
T18489 33357-33362 NN denotes mouse
T18490 33371-33372 -LRB- denotes (
T18491 33372-33375 NN denotes E13
T18492 33375-33376 -RRB- denotes )
T18493 33376-33377 . denotes .
T18494 33377-33478 sentence denotes For collagen matrix assays, DRGs were dissected out under a stereomicroscope using tungsten needles.
T18495 33378-33381 IN denotes For
T18496 33416-33425 VBN denotes dissected
T18497 33382-33390 NN denotes collagen
T18498 33391-33397 NN denotes matrix
T18499 33398-33404 NNS denotes assays
T18500 33404-33406 , denotes ,
T18501 33406-33410 NNS denotes DRGs
T18502 33411-33415 VBD denotes were
T18503 33426-33429 RP denotes out
T18504 33430-33435 IN denotes under
T18505 33436-33437 DT denotes a
T18506 33438-33454 NN denotes stereomicroscope
T18507 33455-33460 VBG denotes using
T18508 33461-33469 NN denotes tungsten
T18509 33470-33477 NNS denotes needles
T18510 33477-33478 . denotes .
T18511 33478-33664 sentence denotes Collagen matrix was prepared with 430 μl of collagen (3 mg/ml dissolved in 0.1M acetic acid, Sigma), 50 μl of 10X DMEM medium, and 2.5 μl of 0.8 M NaCa2, and the pH was adjusted to 7.5.
T18512 33479-33487 NN denotes Collagen
T18513 33488-33494 NN denotes matrix
T18514 33499-33507 VBN denotes prepared
T18515 33495-33498 VBD denotes was
T18516 33508-33512 IN denotes with
T18517 33513-33516 CD denotes 430
T18518 33517-33519 NN denotes μl
T18519 33520-33522 IN denotes of
T18520 33523-33531 NN denotes collagen
T18521 33532-33533 -LRB- denotes (
T18522 33572-33577 NNP denotes Sigma
T18523 33533-33534 CD denotes 3
T18524 33535-33537 NN denotes mg
T18525 33537-33538 SYM denotes /
T18526 33538-33540 NN denotes ml
T18527 33541-33550 VBN denotes dissolved
T18528 33551-33553 IN denotes in
T18529 33554-33557 CD denotes 0.1
T18530 33557-33558 NN denotes M
T18531 33566-33570 NN denotes acid
T18532 33559-33565 JJ denotes acetic
T18533 33570-33572 , denotes ,
T18534 33577-33578 -RRB- denotes )
T18535 33578-33580 , denotes ,
T18536 33580-33582 CD denotes 50
T18537 33583-33585 NN denotes μl
T18538 33586-33588 IN denotes of
T18539 33589-33591 CD denotes 10
T18540 33593-33597 NN denotes DMEM
T18541 33591-33592 NN denotes X
T18542 33598-33604 NN denotes medium
T18543 33604-33606 , denotes ,
T18544 33606-33609 CC denotes and
T18545 33610-33613 CD denotes 2.5
T18546 33614-33616 NN denotes μl
T18547 33617-33619 IN denotes of
T18548 33620-33623 CD denotes 0.8
T18549 33624-33625 NN denotes M
T18550 33626-33631 NN denotes NaCa2
T18551 33631-33633 , denotes ,
T18552 33633-33636 CC denotes and
T18553 33637-33640 DT denotes the
T18554 33641-33643 NN denotes pH
T18555 33648-33656 VBN denotes adjusted
T18556 33644-33647 VBD denotes was
T18557 33657-33659 IN denotes to
T18558 33660-33663 CD denotes 7.5
T18559 33663-33664 . denotes .
T18560 33664-33767 sentence denotes Individual ganglion explants were placed in 24-well plates and covered with freshly prepared collagen.
T18561 33665-33675 JJ denotes Individual
T18562 33685-33693 NNS denotes explants
T18563 33676-33684 NN denotes ganglion
T18564 33699-33705 VBN denotes placed
T18565 33694-33698 VBD denotes were
T18566 33706-33708 IN denotes in
T18567 33709-33711 CD denotes 24
T18568 33712-33716 NN denotes well
T18569 33711-33712 HYPH denotes -
T18570 33717-33723 NNS denotes plates
T18571 33724-33727 CC denotes and
T18572 33728-33735 VBN denotes covered
T18573 33736-33740 IN denotes with
T18574 33741-33748 RB denotes freshly
T18575 33749-33757 VBN denotes prepared
T18576 33758-33766 NN denotes collagen
T18577 33766-33767 . denotes .
T18578 33767-33829 sentence denotes Sepharose beads with an average diameter of 150 μm were used.
T18579 33768-33777 NN denotes Sepharose
T18580 33778-33783 NNS denotes beads
T18581 33824-33828 VBN denotes used
T18582 33784-33788 IN denotes with
T18583 33789-33791 DT denotes an
T18584 33800-33808 NN denotes diameter
T18585 33792-33799 JJ denotes average
T18586 33809-33811 IN denotes of
T18587 33812-33815 CD denotes 150
T18588 33816-33818 NN denotes μm
T18589 33819-33823 VBD denotes were
T18590 33828-33829 . denotes .
T18591 33829-33996 sentence denotes Beads were washed twice with PBS, air dried, and loaded with 10, 20, 50, or 100 ng/μl NT-3 (Collaborative Research, Chemicon) at 4 °C overnight with constant shaking.
T18592 33830-33835 NNS denotes Beads
T18593 33841-33847 VBN denotes washed
T18594 33836-33840 VBD denotes were
T18595 33848-33853 RB denotes twice
T18596 33854-33858 IN denotes with
T18597 33859-33862 NN denotes PBS
T18598 33862-33864 , denotes ,
T18599 33864-33867 NN denotes air
T18600 33868-33873 VBN denotes dried
T18601 33873-33875 , denotes ,
T18602 33875-33878 CC denotes and
T18603 33879-33885 VBN denotes loaded
T18604 33886-33890 IN denotes with
T18605 33891-33893 CD denotes 10
T18606 33910-33912 NN denotes ng
T18607 33893-33895 , denotes ,
T18608 33895-33897 CD denotes 20
T18609 33897-33899 , denotes ,
T18610 33899-33901 CD denotes 50
T18611 33901-33903 , denotes ,
T18612 33903-33905 CC denotes or
T18613 33906-33909 CD denotes 100
T18614 33916-33918 NN denotes NT
T18615 33912-33913 SYM denotes /
T18616 33913-33915 NN denotes μl
T18617 33918-33919 HYPH denotes -
T18618 33919-33920 CD denotes 3
T18619 33921-33922 -LRB- denotes (
T18620 33936-33944 NN denotes Research
T18621 33922-33935 JJ denotes Collaborative
T18622 33944-33946 , denotes ,
T18623 33946-33954 NNP denotes Chemicon
T18624 33954-33955 -RRB- denotes )
T18625 33956-33958 IN denotes at
T18626 33959-33960 CD denotes 4
T18627 33961-33963 NN denotes °C
T18628 33964-33973 RB denotes overnight
T18629 33974-33978 IN denotes with
T18630 33979-33987 JJ denotes constant
T18631 33988-33995 NN denotes shaking
T18632 33995-33996 . denotes .
T18633 33996-34068 sentence denotes For negative control, beads were loaded with BSA (10–100 ng/μl) or PBS.
T18634 33997-34000 IN denotes For
T18635 34030-34036 VBN denotes loaded
T18636 34001-34009 JJ denotes negative
T18637 34010-34017 NN denotes control
T18638 34017-34019 , denotes ,
T18639 34019-34024 NNS denotes beads
T18640 34025-34029 VBD denotes were
T18641 34037-34041 IN denotes with
T18642 34042-34045 NN denotes BSA
T18643 34046-34047 -LRB- denotes (
T18644 34054-34056 NN denotes ng
T18645 34047-34049 CD denotes 10
T18646 34050-34053 CD denotes 100
T18647 34049-34050 HYPH denotes –
T18648 34056-34057 SYM denotes /
T18649 34057-34059 NN denotes μl
T18650 34059-34060 -RRB- denotes )
T18651 34061-34063 CC denotes or
T18652 34064-34067 NN denotes PBS
T18653 34067-34068 . denotes .
T18654 34068-34211 sentence denotes Either a single neurotrophin-loaded bead or a single BSA (or PBS)–loaded bead was implanted about 200–1,200 μm away from the ganglion explant.
T18655 34069-34075 CC denotes Either
T18656 34105-34109 NN denotes bead
T18657 34076-34077 DT denotes a
T18658 34078-34084 JJ denotes single
T18659 34085-34097 NN denotes neurotrophin
T18660 34098-34104 VBN denotes loaded
T18661 34097-34098 HYPH denotes -
T18662 34151-34160 VBN denotes implanted
T18663 34110-34112 CC denotes or
T18664 34113-34114 DT denotes a
T18665 34142-34146 NN denotes bead
T18666 34115-34121 JJ denotes single
T18667 34122-34125 NN denotes BSA
T18668 34135-34141 VBN denotes loaded
T18669 34126-34127 -LRB- denotes (
T18670 34127-34129 CC denotes or
T18671 34130-34133 NN denotes PBS
T18672 34133-34134 -RRB- denotes )
T18673 34134-34135 HYPH denotes –
T18674 34147-34150 VBD denotes was
T18675 34161-34166 IN denotes about
T18676 34171-34176 CD denotes 1,200
T18677 34167-34170 CD denotes 200
T18678 34170-34171 HYPH denotes –
T18679 34177-34179 NN denotes μm
T18680 34180-34184 RB denotes away
T18681 34185-34189 IN denotes from
T18682 34190-34193 DT denotes the
T18683 34203-34210 NN denotes explant
T18684 34194-34202 NN denotes ganglion
T18685 34210-34211 . denotes .
T18686 34211-34301 sentence denotes Collagen-embedded cultures were then placed at 33 °C for 15 min for the matrix to harden.
T18687 34212-34220 NN denotes Collagen
T18688 34221-34229 VBN denotes embedded
T18689 34220-34221 HYPH denotes -
T18690 34230-34238 NNS denotes cultures
T18691 34249-34255 VBN denotes placed
T18692 34239-34243 VBD denotes were
T18693 34244-34248 RB denotes then
T18694 34256-34258 IN denotes at
T18695 34259-34261 CD denotes 33
T18696 34262-34264 NN denotes °C
T18697 34265-34268 IN denotes for
T18698 34269-34271 CD denotes 15
T18699 34272-34275 NN denotes min
T18700 34276-34279 IN denotes for
T18701 34294-34300 VB denotes harden
T18702 34280-34283 DT denotes the
T18703 34284-34290 NN denotes matrix
T18704 34291-34293 TO denotes to
T18705 34300-34301 . denotes .
T18706 34301-34356 sentence denotes Serum-free culture medium was then added to each well.
T18707 34302-34307 NN denotes Serum
T18708 34308-34312 JJ denotes free
T18709 34307-34308 HYPH denotes -
T18710 34321-34327 NN denotes medium
T18711 34313-34320 NN denotes culture
T18712 34337-34342 VBN denotes added
T18713 34328-34331 VBD denotes was
T18714 34332-34336 RB denotes then
T18715 34343-34345 IN denotes to
T18716 34346-34350 DT denotes each
T18717 34351-34355 NN denotes well
T18718 34355-34356 . denotes .
T18719 34356-34456 sentence denotes In cultures with WT DRG and control beads, 10% serum was added to ensure viability of the explants.
T18720 34357-34359 IN denotes In
T18721 34414-34419 VBN denotes added
T18722 34360-34368 NNS denotes cultures
T18723 34369-34373 IN denotes with
T18724 34374-34376 NN denotes WT
T18725 34377-34380 NN denotes DRG
T18726 34381-34384 CC denotes and
T18727 34385-34392 NN denotes control
T18728 34393-34398 NNS denotes beads
T18729 34398-34400 , denotes ,
T18730 34400-34402 CD denotes 10
T18731 34402-34403 NN denotes %
T18732 34404-34409 NN denotes serum
T18733 34410-34413 VBD denotes was
T18734 34420-34422 TO denotes to
T18735 34423-34429 VB denotes ensure
T18736 34430-34439 NN denotes viability
T18737 34440-34442 IN denotes of
T18738 34443-34446 DT denotes the
T18739 34447-34455 NNS denotes explants
T18740 34455-34456 . denotes .
T18741 34456-34574 sentence denotes TrkC-Fc (Regeneron Pharmaceuticals, Tarrytown, New York, United States) was added (20 μg/ml) into the culture medium.
T18742 34457-34461 NN denotes TrkC
T18743 34462-34464 NN denotes Fc
T18744 34461-34462 HYPH denotes -
T18745 34533-34538 VBN denotes added
T18746 34465-34466 -LRB- denotes (
T18747 34476-34491 NNP denotes Pharmaceuticals
T18748 34466-34475 NNP denotes Regeneron
T18749 34491-34493 , denotes ,
T18750 34493-34502 NNP denotes Tarrytown
T18751 34502-34504 , denotes ,
T18752 34504-34507 NNP denotes New
T18753 34508-34512 NNP denotes York
T18754 34512-34514 , denotes ,
T18755 34514-34520 NNP denotes United
T18756 34521-34527 NNP denotes States
T18757 34527-34528 -RRB- denotes )
T18758 34529-34532 VBD denotes was
T18759 34539-34540 -LRB- denotes (
T18760 34543-34545 NN denotes μg
T18761 34540-34542 CD denotes 20
T18762 34545-34546 SYM denotes /
T18763 34546-34548 NN denotes ml
T18764 34548-34549 -RRB- denotes )
T18765 34550-34554 IN denotes into
T18766 34555-34558 DT denotes the
T18767 34567-34573 NN denotes medium
T18768 34559-34566 NN denotes culture
T18769 34573-34574 . denotes .
T19117 34576-34583 NN denotes Explant
T19118 34584-34595 NNS denotes co-cultures
T19119 34595-34727 sentence denotes Spinal cords with attached DRGs were dissected out from Swiss Webster mouse embryos at E13, and sectioned into 300-μm-thick slices.
T19120 34596-34602 JJ denotes Spinal
T19121 34603-34608 NNS denotes cords
T19122 34633-34642 VBN denotes dissected
T19123 34609-34613 IN denotes with
T19124 34614-34622 VBN denotes attached
T19125 34623-34627 NNS denotes DRGs
T19126 34628-34632 VBD denotes were
T19127 34643-34646 RP denotes out
T19128 34647-34651 IN denotes from
T19129 34652-34657 NNP denotes Swiss
T19130 34658-34665 NNP denotes Webster
T19131 34672-34679 NNS denotes embryos
T19132 34666-34671 NN denotes mouse
T19133 34680-34682 IN denotes at
T19134 34683-34686 NN denotes E13
T19135 34686-34688 , denotes ,
T19136 34688-34691 CC denotes and
T19137 34692-34701 VBN denotes sectioned
T19138 34702-34706 IN denotes into
T19139 34707-34710 CD denotes 300
T19140 34711-34713 NN denotes μm
T19141 34710-34711 HYPH denotes -
T19142 34714-34719 JJ denotes thick
T19143 34713-34714 HYPH denotes -
T19144 34720-34726 NNS denotes slices
T19145 34726-34727 . denotes .
T19146 34727-34842 sentence denotes Tissue slices were placed on Millicell Tissue Culture Inserts (Millipore, Billrica, Massachusetts, United States).
T19147 34728-34734 NN denotes Tissue
T19148 34735-34741 NNS denotes slices
T19149 34747-34753 VBN denotes placed
T19150 34742-34746 VBD denotes were
T19151 34754-34756 IN denotes on
T19152 34757-34766 NN denotes Millicell
T19153 34782-34789 NNS denotes Inserts
T19154 34767-34773 NN denotes Tissue
T19155 34774-34781 NN denotes Culture
T19156 34790-34791 -LRB- denotes (
T19157 34791-34800 NNP denotes Millipore
T19158 34800-34802 , denotes ,
T19159 34802-34810 NNP denotes Billrica
T19160 34810-34812 , denotes ,
T19161 34812-34825 NNP denotes Massachusetts
T19162 34825-34827 , denotes ,
T19163 34827-34833 NNP denotes United
T19164 34834-34840 NNP denotes States
T19165 34840-34841 -RRB- denotes )
T19166 34841-34842 . denotes .
T19167 34842-34987 sentence denotes NT-3-loaded (n = 15) or PBS-loaded (n = 6) sepharose beads were prepared as described above, and placed in the midline at mid-spinal cord level.
T19168 34843-34845 NN denotes NT
T19169 34848-34854 VBN denotes loaded
T19170 34845-34846 HYPH denotes -
T19171 34846-34847 CD denotes 3
T19172 34847-34848 HYPH denotes -
T19173 34896-34901 NNS denotes beads
T19174 34855-34856 -LRB- denotes (
T19175 34860-34862 CD denotes 15
T19176 34856-34857 NN denotes n
T19177 34858-34859 SYM denotes =
T19178 34862-34863 -RRB- denotes )
T19179 34864-34866 CC denotes or
T19180 34867-34870 NN denotes PBS
T19181 34871-34877 VBN denotes loaded
T19182 34870-34871 HYPH denotes -
T19183 34878-34879 -LRB- denotes (
T19184 34883-34884 CD denotes 6
T19185 34879-34880 NN denotes n
T19186 34881-34882 SYM denotes =
T19187 34884-34885 -RRB- denotes )
T19188 34886-34895 NN denotes sepharose
T19189 34907-34915 VBN denotes prepared
T19190 34902-34906 VBD denotes were
T19191 34916-34918 IN denotes as
T19192 34919-34928 VBN denotes described
T19193 34929-34934 RB denotes above
T19194 34934-34936 , denotes ,
T19195 34936-34939 CC denotes and
T19196 34940-34946 VBN denotes placed
T19197 34947-34949 IN denotes in
T19198 34950-34953 DT denotes the
T19199 34954-34961 NN denotes midline
T19200 34962-34964 IN denotes at
T19201 34965-34975 JJ denotes mid-spinal
T19202 34976-34980 NN denotes cord
T19203 34981-34986 NN denotes level
T19204 34986-34987 . denotes .
T19205 34987-35130 sentence denotes Inserts were placed in six-well plates with serum-free medium at the bottom of the wells, and kept at 33 °C for 3 d in the presence of 5% CO2.
T19206 34988-34995 NNS denotes Inserts
T19207 35001-35007 VBN denotes placed
T19208 34996-35000 VBD denotes were
T19209 35008-35010 IN denotes in
T19210 35011-35014 CD denotes six
T19211 35015-35019 NN denotes well
T19212 35014-35015 HYPH denotes -
T19213 35020-35026 NNS denotes plates
T19214 35027-35031 IN denotes with
T19215 35032-35037 NN denotes serum
T19216 35038-35042 JJ denotes free
T19217 35037-35038 HYPH denotes -
T19218 35043-35049 NN denotes medium
T19219 35050-35052 IN denotes at
T19220 35053-35056 DT denotes the
T19221 35057-35063 NN denotes bottom
T19222 35064-35066 IN denotes of
T19223 35067-35070 DT denotes the
T19224 35071-35076 NNS denotes wells
T19225 35076-35078 , denotes ,
T19226 35078-35081 CC denotes and
T19227 35082-35086 VBD denotes kept
T19228 35087-35089 IN denotes at
T19229 35090-35092 CD denotes 33
T19230 35093-35095 NN denotes °C
T19231 35096-35099 IN denotes for
T19232 35100-35101 CD denotes 3
T19233 35102-35103 NN denotes d
T19234 35104-35106 IN denotes in
T19235 35107-35110 DT denotes the
T19236 35111-35119 NN denotes presence
T19237 35120-35122 IN denotes of
T19238 35123-35124 CD denotes 5
T19239 35124-35125 NN denotes %
T19240 35126-35129 NN denotes CO2
T19241 35129-35130 . denotes .
T19242 35130-35241 sentence denotes Cultures were then fixed with 4% paraformaldehyde in PBS, and small crystals of DiI were placed into the DRGs.
T19243 35131-35139 NNS denotes Cultures
T19244 35150-35155 VBN denotes fixed
T19245 35140-35144 VBD denotes were
T19246 35145-35149 RB denotes then
T19247 35156-35160 IN denotes with
T19248 35161-35162 CD denotes 4
T19249 35162-35163 NN denotes %
T19250 35164-35180 NN denotes paraformaldehyde
T19251 35181-35183 IN denotes in
T19252 35184-35187 NN denotes PBS
T19253 35187-35189 , denotes ,
T19254 35189-35192 CC denotes and
T19255 35193-35198 JJ denotes small
T19256 35199-35207 NNS denotes crystals
T19257 35220-35226 VBN denotes placed
T19258 35208-35210 IN denotes of
T19259 35211-35214 NN denotes DiI
T19260 35215-35219 VBD denotes were
T19261 35227-35231 IN denotes into
T19262 35232-35235 DT denotes the
T19263 35236-35240 NNS denotes DRGs
T19264 35240-35241 . denotes .
T19265 35241-35397 sentence denotes Samples were incubated in a 37-°C incubator, allowing the dye to diffuse, and photographed under a Nikon (Tokyo, Japan) inverted epifluoresence microscope.
T19266 35242-35249 NNS denotes Samples
T19267 35255-35264 VBN denotes incubated
T19268 35250-35254 VBD denotes were
T19269 35265-35267 IN denotes in
T19270 35268-35269 DT denotes a
T19271 35276-35285 NN denotes incubator
T19272 35270-35272 CD denotes 37
T19273 35273-35275 NN denotes °C
T19274 35272-35273 HYPH denotes -
T19275 35285-35287 , denotes ,
T19276 35287-35295 VBG denotes allowing
T19277 35296-35299 DT denotes the
T19278 35300-35303 NN denotes dye
T19279 35307-35314 VB denotes diffuse
T19280 35304-35306 TO denotes to
T19281 35314-35316 , denotes ,
T19282 35316-35319 CC denotes and
T19283 35320-35332 VBN denotes photographed
T19284 35333-35338 IN denotes under
T19285 35339-35340 DT denotes a
T19286 35386-35396 NN denotes microscope
T19287 35341-35346 NNP denotes Nikon
T19288 35347-35348 -LRB- denotes (
T19289 35348-35353 NNP denotes Tokyo
T19290 35353-35355 , denotes ,
T19291 35355-35360 NNP denotes Japan
T19292 35360-35361 -RRB- denotes )
T19293 35362-35370 JJ denotes inverted
T19294 35371-35385 NN denotes epifluoresence
T19295 35396-35397 . denotes .
T428 128-130 NN denotes NT
T429 130-131 HYPH denotes -
T430 131-132 CD denotes 3
T431 132-133 -RRB- denotes )
T432 134-136 VBZ denotes is
T433 146-149 IN denotes for
T434 150-164 JJ denotes proprioceptive
T435 165-171 NN denotes neuron
T436 172-180 NN denotes survival
T437 180-181 . denotes .
T438 181-345 sentence denotes Deletion of the proapoptotic gene Bax in NT-3 knockout mice rescues these neurons and allows for examination of their axon growth in the absence of NT-3 signaling.
T439 182-190 NN denotes Deletion
T440 242-249 VBZ denotes rescues
T441 191-193 IN denotes of
T442 194-197 DT denotes the
T443 211-215 NN denotes gene
T444 198-210 JJ denotes proapoptotic
T445 216-219 NN denotes Bax
T446 220-222 IN denotes in
T447 223-225 NN denotes NT
T448 228-236 NN denotes knockout
T449 225-226 HYPH denotes -
T450 226-227 CD denotes 3
T451 237-241 NNS denotes mice
T452 250-255 DT denotes these
T453 256-263 NNS denotes neurons
T454 264-267 CC denotes and
T455 268-274 VBZ denotes allows
T456 275-278 IN denotes for
T457 279-290 NN denotes examination
T458 291-293 IN denotes of
T459 294-299 PRP$ denotes their
T460 305-311 NN denotes growth
T461 300-304 NN denotes axon
T462 312-314 IN denotes in
T463 315-318 DT denotes the
T464 319-326 NN denotes absence
T465 327-329 IN denotes of
T466 330-332 NN denotes NT
T467 335-344 NN denotes signaling
T468 332-333 HYPH denotes -
T469 333-334 CD denotes 3
T470 344-345 . denotes .
T471 345-515 sentence denotes TrkC-positive peripheral and central axons from dorsal root ganglia follow proper trajectories and arrive in close proximity to their targets but fail to innervate them.
T472 346-350 NN denotes TrkC
T473 351-359 JJ denotes positive
T474 350-351 HYPH denotes -
T475 383-388 NNS denotes axons
T476 360-370 JJ denotes peripheral
T477 371-374 CC denotes and
T478 375-382 JJ denotes central
T479 414-420 VBP denotes follow
T480 389-393 IN denotes from
T481 394-400 JJ denotes dorsal
T482 401-405 NN denotes root
T483 406-413 NNS denotes ganglia
T484 421-427 JJ denotes proper
T485 428-440 NNS denotes trajectories
T486 441-444 CC denotes and
T487 445-451 VBP denotes arrive
T488 452-454 IN denotes in
T489 455-460 JJ denotes close
T490 461-470 NN denotes proximity
T491 471-473 IN denotes to
T492 474-479 PRP$ denotes their
T493 480-487 NNS denotes targets
T408 0-1 DT denotes A
T409 18-22 NN denotes Role
T410 0-63 sentence denotes A Chemoattractant Role for NT-3 in Proprioceptive Axon Guidance
T411 2-17 NN denotes Chemoattractant
T412 23-26 IN denotes for
T413 27-29 NN denotes NT
T414 29-30 HYPH denotes -
T415 30-31 CD denotes 3
T416 32-34 IN denotes in
T417 35-49 NN denotes Proprioceptive
T418 50-54 NN denotes Axon
T419 55-63 NN denotes Guidance
T420 63-64 sentence denotes
T422 64-181 sentence denotes NT-3 and Proprioceptive Axon Guidance Abstract Neurotrophin-3 (NT-3) is required for proprioceptive neuron survival.
T423 64-124 NN denotes NT-3 and Proprioceptive Axon Guidance Abstract Neurotrophin
T424 137-145 VBN denotes required
T425 124-125 HYPH denotes -
T426 125-126 CD denotes 3
T427 127-128 -LRB- denotes (
T494 488-491 CC denotes but
T495 492-496 VBP denotes fail
T496 497-499 TO denotes to
T497 500-509 VB denotes innervate
T498 510-514 PRP denotes them
T499 514-515 . denotes .
T500 515-615 sentence denotes Peripherally, muscle spindles are absent and TrkC-positive axons do not enter their target muscles.
T501 516-528 RB denotes Peripherally
T502 546-549 VBP denotes are
T503 528-530 , denotes ,
T504 530-536 NN denotes muscle
T505 537-545 NNS denotes spindles
T506 550-556 JJ denotes absent
T507 557-560 CC denotes and
T508 561-565 NN denotes TrkC
T509 566-574 JJ denotes positive
T510 565-566 HYPH denotes -
T511 575-580 NNS denotes axons
T512 588-593 VB denotes enter
T516 607-614 NNS denotes muscles
T517 600-606 NN denotes target
T513 581-583 VBP denotes do
T518 614-615 . denotes .
T514 584-587 RB denotes not
T515 594-599 PRP$ denotes their
T519 615-720 sentence denotes Centrally, proprioceptive axons branch in ectopic regions of the spinal cord, even crossing the midline.
T520 616-625 RB denotes Centrally
T521 648-654 VBP denotes branch
T522 625-627 , denotes ,
T523 627-641 JJ denotes proprioceptive
T524 642-647 NNS denotes axons
T525 655-657 IN denotes in
T526 658-665 JJ denotes ectopic
T527 666-673 NNS denotes regions
T528 674-676 IN denotes of
T529 677-680 DT denotes the
T530 688-692 NN denotes cord
T531 681-687 JJ denotes spinal
T532 692-694 , denotes ,
T533 694-698 RB denotes even
T534 699-707 VBG denotes crossing
T535 708-711 DT denotes the
T536 712-719 NN denotes midline
T537 719-720 . denotes .
T538 720-806 sentence denotes In vitro assays reveal chemoattractant effects of NT-3 on dorsal root ganglion axons.
T539 721-723 FW denotes In
T540 724-729 FW denotes vitro
T541 730-736 NNS denotes assays
T542 737-743 VBP denotes reveal
T543 744-759 NN denotes chemoattractant
T544 760-767 NNS denotes effects
T545 768-770 IN denotes of
T546 771-773 NN denotes NT
T547 773-774 HYPH denotes -
T548 774-775 CD denotes 3
T549 776-778 IN denotes on
T550 779-785 JJ denotes dorsal
T551 786-790 NN denotes root
T552 791-799 NN denotes ganglion
T553 800-805 NNS denotes axons
T554 805-806 . denotes .
T555 806-965 sentence denotes Our results show that survival factor NT-3 acts as a short-distance axon guidance molecule for muscle sensory afferents as they approach their proper targets.
T556 807-810 PRP$ denotes Our
T557 811-818 NNS denotes results
T558 819-823 VBP denotes show
T559 824-828 IN denotes that
T560 850-854 VBZ denotes acts
T561 829-837 NN denotes survival
T562 838-844 NN denotes factor
T563 845-847 NN denotes NT
T564 847-848 HYPH denotes -
T565 848-849 CD denotes 3
T566 855-857 IN denotes as
T567 858-859 DT denotes a
T568 889-897 NN denotes molecule
T569 860-865 JJ denotes short
T570 866-874 NN denotes distance
T571 865-866 HYPH denotes -
T572 875-879 NN denotes axon
T573 880-888 NN denotes guidance
T574 898-901 IN denotes for
T575 902-908 NN denotes muscle
T576 917-926 NNS denotes afferents
T577 909-916 NN denotes sensory
T578 927-929 IN denotes as
T579 935-943 VBP denotes approach
T580 930-934 PRP denotes they
T581 944-949 PRP$ denotes their
T582 957-964 NNS denotes targets
T583 950-956 JJ denotes proper
T584 964-965 . denotes .
T1178 1100-1112 NN denotes Neurotrophin
T1179 1122-1124 VBZ denotes is
T1259 1502-1503 -RRB- denotes )
T1260 1504-1506 CC denotes or
T1180 1112-1113 HYPH denotes -
T1181 1113-1114 CD denotes 3
T1182 1115-1116 -LRB- denotes (
T1183 1116-1118 NN denotes NT
T1184 1118-1119 HYPH denotes -
T1185 1119-1120 CD denotes 3
T1186 1120-1121 -RRB- denotes )
T1187 1125-1126 DT denotes a
T1188 1131-1142 NN denotes requirement
T1189 1127-1130 JJ denotes key
T1190 1143-1146 IN denotes for
T1191 1147-1150 DT denotes the
T1192 1151-1162 NN denotes development
T1193 1163-1165 IN denotes of
T1194 1166-1180 JJ denotes proprioceptive
T1195 1181-1187 NNS denotes inputs
T1196 1188-1190 IN denotes to
T1197 1191-1196 JJ denotes motor
T1198 1197-1204 NNS denotes neurons
T1199 1205-1206 -LRB- denotes (
T1200 1206-1210 NNP denotes Chen
T1201 1211-1214 CC denotes and
T1202 1215-1220 NNP denotes Frank
T1203 1221-1225 CD denotes 1999
T1204 1225-1226 : denotes ;
T1205 1227-1231 NNP denotes Chen
T1206 1232-1234 FW denotes et
T1207 1235-1238 FW denotes al.
T1208 1239-1243 CD denotes 2003
T1209 1243-1244 -RRB- denotes )
T1210 1244-1245 . denotes .
T1211 1245-1664 sentence denotes Mice deficient in NT-3, its tyrosine kinase receptor, TrkC, or in TrkC-positive neuron-specific transcription factor Runx3 display severe ataxia associated with the absence of muscle spindles, and loss of proprioceptive neurons in dorsal root ganglia (DRGs) or their axons (Ernfors et al. 1994; Klein et al. 1994; Tessarollo et al. 1994; Fariñas et al. 1996; Liebl et al. 1997; Inoue et al. 2002; Levanon et al. 2002).
T1212 1246-1250 NNS denotes Mice
T1213 1369-1376 VBP denotes display
T1214 1251-1260 JJ denotes deficient
T1215 1261-1263 IN denotes in
T1216 1264-1266 NN denotes NT
T1217 1266-1267 HYPH denotes -
T1218 1267-1268 CD denotes 3
T1219 1268-1270 , denotes ,
T1220 1270-1273 PRP$ denotes its
T1221 1290-1298 NN denotes receptor
T1222 1274-1282 NN denotes tyrosine
T1223 1283-1289 NN denotes kinase
T1224 1298-1300 , denotes ,
T1225 1300-1304 NN denotes TrkC
T1226 1304-1306 , denotes ,
T1227 1306-1308 CC denotes or
T1228 1309-1311 IN denotes in
T1229 1312-1316 NN denotes TrkC
T1230 1317-1325 JJ denotes positive
T1231 1316-1317 HYPH denotes -
T1232 1356-1362 NN denotes factor
T1233 1326-1332 NN denotes neuron
T1234 1332-1333 HYPH denotes -
T1235 1333-1341 JJ denotes specific
T1236 1342-1355 NN denotes transcription
T1237 1363-1368 NN denotes Runx3
T1238 1377-1383 JJ denotes severe
T1239 1384-1390 NN denotes ataxia
T1240 1391-1401 VBN denotes associated
T1241 1402-1406 IN denotes with
T1242 1407-1410 DT denotes the
T1243 1411-1418 NN denotes absence
T1244 1419-1421 IN denotes of
T1245 1422-1428 NN denotes muscle
T1246 1429-1437 NNS denotes spindles
T1247 1437-1439 , denotes ,
T1248 1439-1442 CC denotes and
T1249 1443-1447 NN denotes loss
T1250 1448-1450 IN denotes of
T1251 1451-1465 JJ denotes proprioceptive
T1252 1466-1473 NNS denotes neurons
T1253 1474-1476 IN denotes in
T1254 1477-1483 JJ denotes dorsal
T1255 1484-1488 NN denotes root
T1256 1489-1496 NNS denotes ganglia
T1257 1497-1498 -LRB- denotes (
T1258 1498-1502 NNS denotes DRGs
T1261 1507-1512 PRP$ denotes their
T1262 1513-1518 NNS denotes axons
T1263 1519-1520 -LRB- denotes (
T1264 1520-1527 NNP denotes Ernfors
T1265 1528-1530 FW denotes et
T1266 1531-1534 FW denotes al.
T1267 1535-1539 CD denotes 1994
T1268 1539-1540 : denotes ;
T1269 1541-1546 NNP denotes Klein
T1270 1547-1549 FW denotes et
T1271 1550-1553 FW denotes al.
T1272 1554-1558 CD denotes 1994
T1273 1558-1559 : denotes ;
T1274 1560-1570 NNP denotes Tessarollo
T1275 1571-1573 FW denotes et
T1276 1574-1577 FW denotes al.
T1277 1578-1582 CD denotes 1994
T1278 1582-1583 : denotes ;
T1279 1584-1591 NNP denotes Fariñas
T1280 1592-1594 FW denotes et
T1281 1595-1598 FW denotes al.
T1282 1599-1603 CD denotes 1996
T1283 1603-1604 : denotes ;
T1284 1605-1610 NNP denotes Liebl
T1285 1611-1613 FW denotes et
T1286 1614-1617 FW denotes al.
T1287 1618-1622 CD denotes 1997
T1288 1622-1623 : denotes ;
T1289 1624-1629 NNP denotes Inoue
T1290 1630-1632 FW denotes et
T1291 1633-1636 FW denotes al.
T1292 1637-1641 CD denotes 2002
T1293 1641-1642 : denotes ;
T1294 1643-1650 NNP denotes Levanon
T1295 1651-1653 FW denotes et
T1296 1654-1657 FW denotes al.
T1297 1658-1662 CD denotes 2002
T1298 1662-1663 -RRB- denotes )
T1299 1663-1664 . denotes .
T1300 1664-1874 sentence denotes NT-3 is expressed in the ventral spinal cord, in the developing limb buds, and in intrafusal bag fibers of muscle spindles later in development (Copray and Brouwer 1994; Fariñas et al. 1996; Tojo et al. 1996).
T1301 1665-1667 NN denotes NT
T1302 1673-1682 VBN denotes expressed
T1303 1667-1668 HYPH denotes -
T1304 1668-1669 CD denotes 3
T1305 1670-1672 VBZ denotes is
T1306 1683-1685 IN denotes in
T1307 1686-1689 DT denotes the
T1308 1705-1709 NN denotes cord
T1309 1690-1697 JJ denotes ventral
T1310 1698-1704 JJ denotes spinal
T1311 1709-1711 , denotes ,
T1312 1711-1713 IN denotes in
T1313 1714-1717 DT denotes the
T1314 1734-1738 NNS denotes buds
T1315 1718-1728 VBG denotes developing
T1316 1729-1733 NN denotes limb
T1317 1738-1740 , denotes ,
T1318 1740-1743 CC denotes and
T1319 1744-1746 IN denotes in
T1320 1747-1757 JJ denotes intrafusal
T1321 1762-1768 NNS denotes fibers
T1322 1758-1761 NN denotes bag
T1323 1769-1771 IN denotes of
T1324 1772-1778 NN denotes muscle
T1325 1779-1787 NNS denotes spindles
T1326 1788-1793 RB denotes later
T1327 1794-1796 IN denotes in
T1328 1797-1808 NN denotes development
T1329 1809-1810 -LRB- denotes (
T1330 1810-1816 NNP denotes Copray
T1331 1817-1820 CC denotes and
T1332 1821-1828 NNP denotes Brouwer
T1333 1829-1833 CD denotes 1994
T1334 1833-1834 : denotes ;
T1335 1835-1842 NNP denotes Fariñas
T1336 1843-1845 FW denotes et
T1337 1846-1849 FW denotes al.
T1338 1850-1854 CD denotes 1996
T1339 1854-1855 : denotes ;
T1340 1856-1860 NNP denotes Tojo
T1341 1861-1863 FW denotes et
T1396 2154-2163 VBN denotes decreased
T1397 2164-2175 NN denotes innervation
T1398 2176-2178 IN denotes of
T1399 2179-2184 NN denotes motor
T1400 2185-2192 NNS denotes neurons
T1401 2193-2194 -LRB- denotes (
T1402 2194-2200 NNP denotes Oakley
T1403 2201-2203 FW denotes et
T1404 2204-2207 FW denotes al.
T1405 2208-2212 CD denotes 1995
T1406 2212-2214 , denotes ,
T1407 2214-2218 CD denotes 1997
T1408 2218-2219 -RRB- denotes )
T1392 2133-2141 JJ denotes positive
T1393 2132-2133 HYPH denotes -
T1394 2142-2149 NNS denotes neurons
T1395 2150-2153 CC denotes and
T1342 1864-1867 FW denotes al.
T1343 1868-1872 CD denotes 1996
T1344 1872-1873 -RRB- denotes )
T1345 1873-1874 . denotes .
T1346 1874-2018 sentence denotes When sensory axons contact developing myotubes, they induce muscle spindle differentiation, forming ring-like spiral nerve endings around them.
T1347 1875-1879 WRB denotes When
T1348 1894-1901 VBP denotes contact
T1349 1880-1887 JJ denotes sensory
T1350 1888-1893 NNS denotes axons
T1351 1928-1934 VBP denotes induce
T1352 1902-1912 VBG denotes developing
T1353 1913-1921 NNS denotes myotubes
T1354 1921-1923 , denotes ,
T1355 1923-1927 PRP denotes they
T1356 1935-1941 NN denotes muscle
T1357 1942-1949 NN denotes spindle
T1358 1950-1965 NN denotes differentiation
T1359 1965-1967 , denotes ,
T1360 1967-1974 VBG denotes forming
T1361 1975-1979 NN denotes ring
T1362 1980-1984 JJ denotes like
T1363 1979-1980 HYPH denotes -
T1364 1998-2005 NNS denotes endings
T1365 1985-1991 JJ denotes spiral
T1366 1992-1997 NN denotes nerve
T1367 2006-2012 IN denotes around
T1368 2013-2017 PRP denotes them
T1369 2017-2018 . denotes .
T1370 2018-2220 sentence denotes In the chicken embryo, limb ablations or anti-NT-3 antibody injections into limb buds lead to elimination of TrkC-positive neurons and decreased innervation of motor neurons (Oakley et al. 1995, 1997).
T1371 2019-2021 IN denotes In
T1372 2105-2109 VBP denotes lead
T1373 2022-2025 DT denotes the
T1374 2034-2040 NN denotes embryo
T1375 2026-2033 NN denotes chicken
T1376 2040-2042 , denotes ,
T1377 2042-2046 NN denotes limb
T1378 2047-2056 NNS denotes ablations
T1379 2057-2059 CC denotes or
T1380 2060-2067 JJ denotes anti-NT
T1381 2068-2069 CD denotes 3
T1382 2067-2068 HYPH denotes -
T1383 2070-2078 NN denotes antibody
T1384 2079-2089 NNS denotes injections
T1385 2090-2094 IN denotes into
T1386 2095-2099 NN denotes limb
T1387 2100-2104 NNS denotes buds
T1388 2110-2112 IN denotes to
T1389 2113-2124 NN denotes elimination
T1390 2125-2127 IN denotes of
T1391 2128-2132 NN denotes TrkC
T1409 2219-2220 . denotes .
T1410 2220-2422 sentence denotes Is NT-3 only a chemotrophic survival factor for muscle sensory afferents, or does it have additional roles in the development of the proprioceptors and the establishment of the monosynaptic reflex arc?
T1411 2221-2223 VBZ denotes Is
T1412 2224-2226 NN denotes NT
T1413 2226-2227 HYPH denotes -
T1414 2227-2228 CD denotes 3
T1415 2229-2233 RB denotes only
T1416 2258-2264 NN denotes factor
T1417 2234-2235 DT denotes a
T1418 2236-2248 JJ denotes chemotrophic
T1419 2249-2257 NN denotes survival
T1420 2265-2268 IN denotes for
T1421 2269-2275 NN denotes muscle
T1422 2284-2293 NNS denotes afferents
T1423 2276-2283 JJ denotes sensory
T1424 2293-2295 , denotes ,
T1425 2295-2297 CC denotes or
T1426 2298-2302 VBZ denotes does
T1427 2306-2310 VB denotes have
T1428 2303-2305 PRP denotes it
T1429 2311-2321 JJ denotes additional
T1430 2322-2327 NNS denotes roles
T1431 2328-2330 IN denotes in
T1432 2331-2334 DT denotes the
T1433 2335-2346 NN denotes development
T1434 2347-2349 IN denotes of
T1435 2350-2353 DT denotes the
T1436 2354-2368 NNS denotes proprioceptors
T1437 2369-2372 CC denotes and
T1438 2373-2376 DT denotes the
T1439 2377-2390 NN denotes establishment
T1440 2391-2393 IN denotes of
T1441 2394-2397 DT denotes the
T1442 2418-2421 NN denotes arc
T1443 2398-2410 JJ denotes monosynaptic
T1444 2411-2417 NN denotes reflex
T1445 2421-2422 . denotes ?
T1446 2422-2562 sentence denotes Here we provide evidence that NT-3 acts as a chemoattractant for sensory axons during the final phase of their target-directed pathfinding.
T1447 2423-2427 RB denotes Here
T1448 2431-2438 VBP denotes provide
T1449 2428-2430 PRP denotes we
T1450 2439-2447 NN denotes evidence
T1451 2448-2452 IN denotes that
T1452 2458-2462 VBZ denotes acts
T1453 2453-2455 NN denotes NT
T1454 2455-2456 HYPH denotes -
T1455 2456-2457 CD denotes 3
T1456 2463-2465 IN denotes as
T1457 2466-2467 DT denotes a
T1458 2468-2483 NN denotes chemoattractant
T1459 2484-2487 IN denotes for
T1460 2488-2495 JJ denotes sensory
T1461 2496-2501 NNS denotes axons
T1462 2502-2508 IN denotes during
T1463 2509-2512 DT denotes the
T1464 2519-2524 NN denotes phase
T1465 2513-2518 JJ denotes final
T1466 2525-2527 IN denotes of
T1467 2528-2533 PRP$ denotes their
T1468 2550-2561 NN denotes pathfinding
T1469 2534-2540 NN denotes target
T1470 2541-2549 VBN denotes directed
T1471 2540-2541 HYPH denotes -
T1472 2561-2562 . denotes .
T2324 2573-2577 NN denotes TrkC
T2325 2578-2586 JJ denotes Positive
T2326 2577-2578 HYPH denotes -
T2327 2591-2598 NNS denotes Neurons
T2328 2587-2590 NN denotes DRG
T2329 2603-2610 VBN denotes Rescued
T2330 2599-2602 VBP denotes Are
T2331 2611-2613 IN denotes in
T2332 2614-2617 NN denotes Bax
T2333 2630-2638 NN denotes Knockout
T2334 2617-2618 HYPH denotes /
T2335 2618-2620 NN denotes NT
T2336 2620-2621 HYPH denotes -
T2337 2621-2622 CD denotes 3
T2338 2623-2629 JJ denotes Double
T2339 2639-2643 NNS denotes Mice
T2340 2643-2760 sentence denotes Mice lacking proapoptotic protein Bax allow for distinguishing survival effects of neurotrophins from other effects.
T2341 2644-2648 NNS denotes Mice
T2342 2682-2687 VBP denotes allow
T2343 2649-2656 VBG denotes lacking
T2344 2657-2669 JJ denotes proapoptotic
T2345 2678-2681 NN denotes Bax
T2346 2670-2677 NN denotes protein
T2347 2688-2691 IN denotes for
T2348 2692-2706 VBG denotes distinguishing
T2349 2707-2715 NN denotes survival
T2350 2716-2723 NNS denotes effects
T2351 2724-2726 IN denotes of
T2352 2727-2740 NNS denotes neurotrophins
T2353 2741-2745 IN denotes from
T2354 2746-2751 JJ denotes other
T2355 2752-2759 NNS denotes effects
T2356 2759-2760 . denotes .
T2357 2760-2924 sentence denotes Bax-deficient sensory neurons no longer require neurotrophins for survival (White et al. 1998; Patel et al. 2000), thus they can be used to examine axonal effects.
T2358 2761-2764 NN denotes Bax
T2359 2765-2774 JJ denotes deficient
T2360 2764-2765 HYPH denotes -
T2361 2783-2790 NNS denotes neurons
T2362 2775-2782 JJ denotes sensory
T2363 2801-2808 VBP denotes require
T2364 2791-2793 RB denotes no
T2365 2794-2800 RB denotes longer
T2366 2893-2897 VBN denotes used
T2367 2809-2822 NNS denotes neurotrophins
T2368 2823-2826 IN denotes for
T2369 2827-2835 NN denotes survival
T2370 2836-2837 -LRB- denotes (
T2371 2837-2842 NNP denotes White
T2372 2843-2845 FW denotes et
T2373 2846-2849 FW denotes al.
T2374 2850-2854 CD denotes 1998
T2375 2854-2855 : denotes ;
T2376 2856-2861 NNP denotes Patel
T2377 2862-2864 FW denotes et
T2378 2865-2868 FW denotes al.
T2379 2869-2873 CD denotes 2000
T2380 2873-2874 -RRB- denotes )
T2381 2874-2876 , denotes ,
T2382 2876-2880 RB denotes thus
T2383 2881-2885 PRP denotes they
T2384 2886-2889 MD denotes can
T2385 2890-2892 VB denotes be
T2386 2898-2900 TO denotes to
T2387 2901-2908 VB denotes examine
T2388 2909-2915 JJ denotes axonal
T2389 2916-2923 NNS denotes effects
T2390 2923-2924 . denotes .
T2391 2924-3083 sentence denotes We bred NT-3 heterozygote and Bax knockout (KO) mice to obtain mice with double KO of both NT-3 and Bax genes, and examined proprioceptive axonal projections.
T2392 2925-2927 PRP denotes We
T2393 2928-2932 VBD denotes bred
T2394 2933-2935 NN denotes NT
T2395 2938-2950 NN denotes heterozygote
T2396 2935-2936 HYPH denotes -
T2397 2936-2937 CD denotes 3
T2398 2951-2954 CC denotes and
T2399 2955-2958 NN denotes Bax
T2400 2959-2967 NN denotes knockout
T2401 2973-2977 NNS denotes mice
T2402 2968-2969 -LRB- denotes (
T2403 2969-2971 NN denotes KO
T2404 2971-2972 -RRB- denotes )
T2405 2978-2980 TO denotes to
T2406 2981-2987 VB denotes obtain
T2407 2988-2992 NNS denotes mice
T2408 2993-2997 IN denotes with
T2409 2998-3004 JJ denotes double
T2410 3005-3007 NN denotes KO
T2411 3008-3010 IN denotes of
T2412 3011-3015 CC denotes both
T2413 3016-3018 NN denotes NT
T2414 3029-3034 NNS denotes genes
T2415 3018-3019 HYPH denotes -
T2416 3019-3020 CD denotes 3
T2417 3021-3024 CC denotes and
T2418 3025-3028 NN denotes Bax
T2419 3034-3036 , denotes ,
T2420 3036-3039 CC denotes and
T2421 3040-3048 VBN denotes examined
T2422 3049-3063 JJ denotes proprioceptive
T2423 3071-3082 NNS denotes projections
T2424 3064-3070 JJ denotes axonal
T2425 3082-3083 . denotes .
T2426 3083-3162 sentence denotes All NT-3 and double KOs died within 48 h after birth (Tessarollo et al. 1994).
T2427 3084-3087 DT denotes All
T2428 3104-3107 NNS denotes KOs
T2429 3088-3090 NN denotes NT
T2430 3090-3091 HYPH denotes -
T2431 3091-3092 CD denotes 3
T2432 3093-3096 CC denotes and
T2433 3097-3103 JJ denotes double
T2434 3108-3112 VBD denotes died
T2435 3113-3119 IN denotes within
T2436 3120-3122 CD denotes 48
T2437 3123-3124 NN denotes h
T2438 3125-3130 IN denotes after
T2439 3131-3136 NN denotes birth
T2440 3137-3138 -LRB- denotes (
T2441 3138-3148 NNP denotes Tessarollo
T2442 3149-3151 FW denotes et
T2443 3152-3155 FW denotes al.
T2444 3156-3160 CD denotes 1994
T2445 3160-3161 -RRB- denotes )
T2446 3161-3162 . denotes .
T2447 3162-3290 sentence denotes We performed TrkA/TrkC double immunohistochemistry (Huang et al. 1999), enabling detection of both proteins in the same sample.
T2448 3163-3165 PRP denotes We
T2449 3166-3175 VBD denotes performed
T2450 3176-3180 NN denotes TrkA
T2451 3181-3185 NN denotes TrkC
T2452 3180-3181 HYPH denotes /
T2453 3193-3213 NN denotes immunohistochemistry
T2454 3186-3192 JJ denotes double
T2455 3214-3215 -LRB- denotes (
T2456 3215-3220 NNP denotes Huang
T2457 3221-3223 FW denotes et
T2458 3224-3227 FW denotes al.
T2459 3228-3232 CD denotes 1999
T2460 3232-3233 -RRB- denotes )
T2461 3233-3235 , denotes ,
T2462 3235-3243 VBG denotes enabling
T2463 3244-3253 NN denotes detection
T2464 3254-3256 IN denotes of
T2465 3257-3261 DT denotes both
T2466 3262-3270 NN denotes proteins
T2467 3271-3273 IN denotes in
T2468 3274-3277 DT denotes the
T2469 3283-3289 NN denotes sample
T2470 3278-3282 JJ denotes same
T2471 3289-3290 . denotes .
T2472 3290-3394 sentence denotes TrkC-positive cells (Figure 1A) and fibers (Figure 1E) were absent in NT-3 KOs at embryonic day (E) 15.
T2473 3291-3295 NN denotes TrkC
T2474 3296-3304 JJ denotes positive
T2475 3295-3296 HYPH denotes -
T2476 3305-3310 NNS denotes cells
T2477 3346-3350 VBD denotes were
T2478 3311-3312 -LRB- denotes (
T2479 3319-3321 NN denotes 1A
T2480 3312-3318 NN denotes Figure
T2481 3321-3322 -RRB- denotes )
T2482 3323-3326 CC denotes and
T2483 3327-3333 NNS denotes fibers
T2484 3334-3335 -LRB- denotes (
T2485 3342-3344 NN denotes 1E
T2486 3335-3341 NN denotes Figure
T2487 3344-3345 -RRB- denotes )
T2488 3351-3357 JJ denotes absent
T2489 3358-3360 IN denotes in
T2490 3361-3363 NN denotes NT
T2491 3366-3369 NNS denotes KOs
T2492 3363-3364 HYPH denotes -
T2493 3364-3365 CD denotes 3
T2494 3370-3372 IN denotes at
T2495 3373-3382 JJ denotes embryonic
T2496 3383-3386 NN denotes day
T2497 3387-3388 -LRB- denotes (
T2498 3388-3389 NN denotes E
T2499 3389-3390 -RRB- denotes )
T2500 3391-3393 CD denotes 15
T2501 3393-3394 . denotes .
T2502 3394-3524 sentence denotes Two subsets of DRG cells expressing either TrkA or TrkC were detected in double KOs, similar to wild-type (WT) or Bax KO animals.
T2503 3395-3398 CD denotes Two
T2504 3399-3406 NNS denotes subsets
T2505 3456-3464 VBN denotes detected
T2506 3407-3409 IN denotes of
T2507 3410-3413 NN denotes DRG
T2508 3414-3419 NNS denotes cells
T2509 3420-3430 VBG denotes expressing
T2510 3431-3437 CC denotes either
T2511 3438-3442 NN denotes TrkA
T2512 3443-3445 CC denotes or
T2513 3446-3450 NN denotes TrkC
T2514 3451-3455 VBD denotes were
T2515 3465-3467 IN denotes in
T2516 3468-3474 JJ denotes double
T2517 3475-3478 NNS denotes KOs
T2518 3478-3480 , denotes ,
T2519 3480-3487 JJ denotes similar
T2520 3488-3490 IN denotes to
T2521 3491-3495 JJ denotes wild
T2522 3496-3500 NN denotes type
T2523 3495-3496 HYPH denotes -
T2524 3516-3523 NNS denotes animals
T2525 3501-3502 -LRB- denotes (
T2526 3502-3504 NN denotes WT
T2527 3504-3505 -RRB- denotes )
T2528 3506-3508 CC denotes or
T2529 3509-3512 NN denotes Bax
T2530 3513-3515 NN denotes KO
T2531 3523-3524 . denotes .
T2532 3524-3731 sentence denotes Surprisingly, at postnatal day (P) 0, a few cells expressed TrkC even in NT-3 KO animals in the Bax +/+ genetic background, and some cells co-expressed TrkA and TrkC, regardless of the genotype (Figure 1B).
T2533 3525-3537 RB denotes Surprisingly
T2534 3575-3584 VBD denotes expressed
T2535 3537-3539 , denotes ,
T2536 3539-3541 IN denotes at
T2537 3542-3551 JJ denotes postnatal
T2538 3552-3555 NN denotes day
T2539 3556-3557 -LRB- denotes (
T2540 3557-3558 NN denotes P
T2541 3558-3559 -RRB- denotes )
T2542 3560-3561 CD denotes 0
T2543 3561-3563 , denotes ,
T2544 3563-3564 DT denotes a
T2545 3569-3574 NNS denotes cells
T2546 3565-3568 JJ denotes few
T2547 3585-3589 NN denotes TrkC
T2548 3590-3594 RB denotes even
T2549 3595-3597 IN denotes in
T2550 3598-3600 NN denotes NT
T2551 3603-3605 NN denotes KO
T2552 3600-3601 HYPH denotes -
T2553 3601-3602 CD denotes 3
T2554 3606-3613 NNS denotes animals
T2555 3614-3616 IN denotes in
T2556 3617-3620 DT denotes the
T2557 3637-3647 NN denotes background
T2558 3621-3624 NN denotes Bax
T2559 3625-3626 SYM denotes +
T2560 3626-3627 HYPH denotes /
T2561 3627-3628 SYM denotes +
T2562 3629-3636 JJ denotes genetic
T2563 3647-3649 , denotes ,
T2564 3649-3652 CC denotes and
T2565 3653-3657 DT denotes some
T2566 3658-3663 NNS denotes cells
T2567 3664-3676 VBD denotes co-expressed
T2568 3677-3681 NN denotes TrkA
T2569 3682-3685 CC denotes and
T2570 3686-3690 NN denotes TrkC
T2571 3690-3692 , denotes ,
T2572 3692-3702 RB denotes regardless
T2573 3703-3705 IN denotes of
T2574 3706-3709 DT denotes the
T2575 3710-3718 NN denotes genotype
T2576 3719-3720 -LRB- denotes (
T2577 3727-3729 NN denotes 1B
T2578 3720-3726 NN denotes Figure
T2579 3729-3730 -RRB- denotes )
T2580 3730-3731 . denotes .
T2581 3731-3885 sentence denotes In order to quantify our results, we analyzed the ratio of TrkA and TrkC immunopositive cells from four different DRGs of animals of different genotypes.
T2582 3732-3734 IN denotes In
T2583 3769-3777 VBD denotes analyzed
T2584 3735-3740 NN denotes order
T2585 3741-3743 TO denotes to
T2586 3744-3752 VB denotes quantify
T2587 3753-3756 PRP$ denotes our
T2588 3757-3764 NNS denotes results
T2589 3764-3766 , denotes ,
T2590 3766-3768 PRP denotes we
T2591 3778-3781 DT denotes the
T2592 3782-3787 NN denotes ratio
T2593 3788-3790 IN denotes of
T2594 3791-3795 NN denotes TrkA
T2595 3805-3819 JJ denotes immunopositive
T2596 3796-3799 CC denotes and
T2597 3800-3804 NN denotes TrkC
T2598 3820-3825 NNS denotes cells
T2599 3826-3830 IN denotes from
T2600 3831-3835 CD denotes four
T2601 3846-3850 NNS denotes DRGs
T2602 3836-3845 JJ denotes different
T2603 3851-3853 IN denotes of
T2604 3854-3861 NNS denotes animals
T2605 3862-3864 IN denotes of
T2606 3865-3874 JJ denotes different
T2607 3875-3884 NNS denotes genotypes
T2608 3884-3885 . denotes .
T2609 3885-4041 sentence denotes At all ages studied, Bax/NT-3 double null DRGs had TrkA/TrkC ratios similar to those of Bax null DRGs, and higher than those of NT-3 null DRGs (Figure 1D).
T2610 3886-3888 IN denotes At
T2611 3933-3936 VBD denotes had
T2612 3889-3892 DT denotes all
T2613 3893-3897 NNS denotes ages
T2614 3898-3905 VBN denotes studied
T2615 3905-3907 , denotes ,
T2616 3907-3910 NN denotes Bax
T2617 3923-3927 JJ denotes null
T2618 3910-3911 HYPH denotes /
T2619 3911-3913 NN denotes NT
T2620 3913-3914 HYPH denotes -
T2621 3914-3915 CD denotes 3
T2622 3916-3922 JJ denotes double
T2623 3928-3932 NNS denotes DRGs
T2624 3937-3941 NN denotes TrkA
T2625 3942-3946 NN denotes TrkC
T2626 3941-3942 HYPH denotes /
T2627 3947-3953 NNS denotes ratios
T2628 3954-3961 JJ denotes similar
T2629 3962-3964 IN denotes to
T2630 3965-3970 DT denotes those
T2631 3971-3973 IN denotes of
T2632 3974-3977 NN denotes Bax
T2633 3978-3982 JJ denotes null
T2634 3983-3987 NNS denotes DRGs
T2635 3987-3989 , denotes ,
T2636 3989-3992 CC denotes and
T2637 3993-3999 JJR denotes higher
T2638 4000-4004 IN denotes than
T2639 4005-4010 DT denotes those
T2640 4011-4013 IN denotes of
T2641 4014-4016 NN denotes NT
T2642 4019-4023 JJ denotes null
T2643 4016-4017 HYPH denotes -
T2644 4017-4018 CD denotes 3
T2645 4024-4028 NNS denotes DRGs
T2646 4029-4030 -LRB- denotes (
T2647 4037-4039 NN denotes 1D
T2648 4030-4036 NN denotes Figure
T2649 4039-4040 -RRB- denotes )
T2650 4040-4041 . denotes .
T2651 4041-4239 sentence denotes TrkC-positive neurons rescued by Bax deletion, however, failed to differentiate properly, as evidenced by the lack of expression of the proprioceptive molecular marker Parvalbumin (PV) (Figure 1C).
T2652 4042-4046 NN denotes TrkC
T2653 4047-4055 JJ denotes positive
T2654 4046-4047 HYPH denotes -
T2655 4056-4063 NNS denotes neurons
T2656 4098-4104 VBD denotes failed
T2657 4064-4071 VBN denotes rescued
T2658 4072-4074 IN denotes by
T2659 4075-4078 NN denotes Bax
T2660 4079-4087 NN denotes deletion
T2661 4087-4089 , denotes ,
T2662 4089-4096 RB denotes however
T2663 4096-4098 , denotes ,
T2664 4105-4107 TO denotes to
T2665 4108-4121 VB denotes differentiate
T2666 4122-4130 RB denotes properly
T2667 4130-4132 , denotes ,
T2668 4132-4134 IN denotes as
T2669 4135-4144 VBN denotes evidenced
T2670 4145-4147 IN denotes by
T2671 4148-4151 DT denotes the
T2672 4152-4156 NN denotes lack
T2673 4157-4159 IN denotes of
T2674 4160-4170 NN denotes expression
T2675 4171-4173 IN denotes of
T2676 4174-4177 DT denotes the
T2677 4203-4209 NN denotes marker
T2678 4178-4192 JJ denotes proprioceptive
T2679 4193-4202 JJ denotes molecular
T2680 4210-4221 NN denotes Parvalbumin
T2681 4222-4223 -LRB- denotes (
T2682 4223-4225 NN denotes PV
T2683 4225-4226 -RRB- denotes )
T2684 4227-4228 -LRB- denotes (
T2685 4235-4237 NN denotes 1C
T2686 4228-4234 NN denotes Figure
T2687 4237-4238 -RRB- denotes )
T2688 4238-4239 . denotes .
T4131 5858-5869 NNS denotes projections
T4132 5850-5857 JJ denotes central
T4133 5870-5872 IN denotes of
T4134 5873-5876 NN denotes DRG
T4135 5877-5882 NNS denotes axons
T3969 5055-5057 NN denotes NT
T3970 5060-5062 VBZ denotes Is
T3971 5057-5058 HYPH denotes -
T3972 5058-5059 CD denotes 3
T3973 5063-5072 JJ denotes Necessary
T3974 5073-5076 IN denotes for
T3975 5077-5083 JJ denotes Proper
T3976 5084-5095 NN denotes Innervation
T3977 5096-5098 IN denotes of
T3978 5099-5104 JJ denotes Motor
T3979 5105-5112 NNS denotes Neurons
T3980 5112-5195 sentence denotes TrkA/TrkC-positive fibers in the spinal cord could be detected at E15 (Figure 1E).
T3981 5113-5117 NN denotes TrkA
T3982 5118-5122 NN denotes TrkC
T3983 5117-5118 HYPH denotes /
T3984 5123-5131 JJ denotes positive
T3985 5122-5123 HYPH denotes -
T3986 5132-5138 NNS denotes fibers
T3987 5167-5175 VBN denotes detected
T3988 5139-5141 IN denotes in
T3989 5142-5145 DT denotes the
T3990 5153-5157 NN denotes cord
T3991 5146-5152 JJ denotes spinal
T3992 5158-5163 MD denotes could
T3993 5164-5166 VB denotes be
T3994 5176-5178 IN denotes at
T3995 5179-5182 NN denotes E15
T3996 5183-5184 -LRB- denotes (
T3997 5191-5193 NN denotes 1E
T3998 5184-5190 NN denotes Figure
T3999 5193-5194 -RRB- denotes )
T4000 5194-5195 . denotes .
T4001 5195-5431 sentence denotes TrkA-positive fibers were restricted to and terminated in the dorsolateral spinal cord, whereas TrkC-positive fibers entered the cord dorsomedially, and descended into the ventral horns in WT (Ozaki and Snider 1997) and Bax KO embryos.
T4002 5196-5200 NN denotes TrkA
T4003 5201-5209 JJ denotes positive
T4004 5200-5201 HYPH denotes -
T4005 5210-5216 NNS denotes fibers
T4006 5222-5232 VBN denotes restricted
T4007 5217-5221 VBD denotes were
T4008 5233-5235 IN denotes to
T4009 5236-5239 CC denotes and
T4010 5240-5250 VBN denotes terminated
T4011 5251-5253 IN denotes in
T4012 5254-5257 DT denotes the
T4013 5278-5282 NN denotes cord
T4014 5258-5270 JJ denotes dorsolateral
T4015 5271-5277 JJ denotes spinal
T4016 5282-5284 , denotes ,
T4017 5284-5291 IN denotes whereas
T4018 5313-5320 VBD denotes entered
T4019 5292-5296 NN denotes TrkC
T4020 5297-5305 JJ denotes positive
T4021 5296-5297 HYPH denotes -
T4022 5306-5312 NNS denotes fibers
T4023 5321-5324 DT denotes the
T4024 5325-5329 NN denotes cord
T4025 5330-5343 RB denotes dorsomedially
T4026 5343-5345 , denotes ,
T4027 5345-5348 CC denotes and
T4028 5349-5358 VBD denotes descended
T4029 5359-5363 IN denotes into
T4030 5364-5367 DT denotes the
T4031 5376-5381 NNS denotes horns
T4032 5368-5375 JJ denotes ventral
T4033 5382-5384 IN denotes in
T4034 5385-5387 NN denotes WT
T4035 5423-5430 NNS denotes embryos
T4036 5388-5389 -LRB- denotes (
T4037 5389-5394 NNP denotes Ozaki
T4038 5395-5398 CC denotes and
T4039 5399-5405 NNP denotes Snider
T4040 5406-5410 CD denotes 1997
T4041 5410-5411 -RRB- denotes )
T4042 5412-5415 CC denotes and
T4043 5416-5419 NN denotes Bax
T4044 5420-5422 NN denotes KO
T4045 5430-5431 . denotes .
T4046 5431-5549 sentence denotes There was no detectable TrkC expression in NT-3 KO spinal cord, indicating complete absence of proprioceptive fibers.
T4047 5432-5437 EX denotes There
T4048 5438-5441 VBD denotes was
T4049 5442-5444 DT denotes no
T4050 5461-5471 NN denotes expression
T4051 5445-5455 JJ denotes detectable
T4052 5456-5460 NN denotes TrkC
T4053 5472-5474 IN denotes in
T4054 5475-5477 NN denotes NT
T4055 5480-5482 NN denotes KO
T4056 5477-5478 HYPH denotes -
T4057 5478-5479 CD denotes 3
T4058 5490-5494 NN denotes cord
T4059 5483-5489 JJ denotes spinal
T4060 5494-5496 , denotes ,
T4061 5496-5506 VBG denotes indicating
T4062 5507-5515 JJ denotes complete
T4063 5516-5523 NN denotes absence
T4064 5524-5526 IN denotes of
T4065 5527-5541 JJ denotes proprioceptive
T4066 5542-5548 NNS denotes fibers
T4067 5548-5549 . denotes .
T4068 5549-5706 sentence denotes In double KO spinal cord, TrkC-positive fibers entered the dorsal spinal cord and descended medially in a manner similar to that seen in WT or Bax KO cases.
T4069 5550-5552 IN denotes In
T4070 5597-5604 VBD denotes entered
T4071 5553-5559 JJ denotes double
T4072 5560-5562 NN denotes KO
T4073 5570-5574 NN denotes cord
T4074 5563-5569 JJ denotes spinal
T4075 5574-5576 , denotes ,
T4076 5576-5580 NN denotes TrkC
T4077 5581-5589 JJ denotes positive
T4078 5580-5581 HYPH denotes -
T4079 5590-5596 NNS denotes fibers
T4080 5605-5608 DT denotes the
T4081 5623-5627 NN denotes cord
T4082 5609-5615 JJ denotes dorsal
T4083 5616-5622 JJ denotes spinal
T4084 5628-5631 CC denotes and
T4085 5632-5641 VBN denotes descended
T4086 5642-5650 RB denotes medially
T4087 5651-5653 IN denotes in
T4088 5654-5655 DT denotes a
T4089 5656-5662 NN denotes manner
T4090 5663-5670 JJ denotes similar
T4091 5671-5673 IN denotes to
T4092 5674-5678 DT denotes that
T4093 5679-5683 VBN denotes seen
T4094 5684-5686 IN denotes in
T4095 5687-5689 NN denotes WT
T4096 5700-5705 NNS denotes cases
T4097 5690-5692 CC denotes or
T4098 5693-5696 NN denotes Bax
T4099 5697-5699 NN denotes KO
T4100 5705-5706 . denotes .
T4101 5706-5828 sentence denotes However, it was not possible to follow TrkC immunolabeled fibers all the way to their terminal zones in any of the cases.
T4102 5707-5714 RB denotes However
T4103 5719-5722 VBD denotes was
T4104 5714-5716 , denotes ,
T4105 5716-5718 PRP denotes it
T4106 5723-5726 RB denotes not
T4107 5727-5735 JJ denotes possible
T4108 5736-5738 TO denotes to
T4109 5739-5745 VB denotes follow
T4110 5746-5750 NN denotes TrkC
T4111 5765-5771 NNS denotes fibers
T4112 5751-5764 VBN denotes immunolabeled
T4113 5772-5775 PDT denotes all
T4114 5780-5783 NN denotes way
T4115 5776-5779 DT denotes the
T4116 5784-5786 IN denotes to
T4117 5787-5792 PRP$ denotes their
T4118 5802-5807 NNS denotes zones
T4119 5793-5801 JJ denotes terminal
T4120 5808-5810 IN denotes in
T4121 5811-5814 DT denotes any
T4122 5815-5817 IN denotes of
T4123 5818-5821 DT denotes the
T4124 5822-5827 NNS denotes cases
T4125 5827-5828 . denotes .
T4126 5828-5920 sentence denotes Next we examined the central projections of DRG axons with the lipophilic tracer DiI at P0.
T4127 5829-5833 RB denotes Next
T4128 5837-5845 VBD denotes examined
T4129 5834-5836 PRP denotes we
T4130 5846-5849 DT denotes the
T4136 5883-5887 IN denotes with
T4137 5888-5891 DT denotes the
T4138 5903-5909 NN denotes tracer
T4139 5892-5902 JJ denotes lipophilic
T4140 5910-5913 NN denotes DiI
T4141 5914-5916 IN denotes at
T4142 5917-5919 NN denotes P0
T4143 5919-5920 . denotes .
T4144 5920-6054 sentence denotes In WT and Bax KO pups, proprioceptive afferents entered the dorsal spinal cord and followed a medial course towards the ventral horn.
T4145 5921-5923 IN denotes In
T4146 5969-5976 VBD denotes entered
T4147 5924-5926 NN denotes WT
T4148 5938-5942 NNS denotes pups
T4149 5927-5930 CC denotes and
T4150 5931-5934 NN denotes Bax
T4151 5935-5937 NN denotes KO
T4152 5942-5944 , denotes ,
T4153 5944-5958 JJ denotes proprioceptive
T4154 5959-5968 NNS denotes afferents
T4155 5977-5980 DT denotes the
T4156 5995-5999 NN denotes cord
T4157 5981-5987 JJ denotes dorsal
T4158 5988-5994 JJ denotes spinal
T4159 6000-6003 CC denotes and
T4160 6004-6012 VBD denotes followed
T4161 6013-6014 DT denotes a
T4162 6022-6028 NN denotes course
T4163 6015-6021 JJ denotes medial
T4164 6029-6036 IN denotes towards
T4165 6037-6040 DT denotes the
T4166 6049-6053 NN denotes horn
T4167 6041-6048 JJ denotes ventral
T4168 6053-6054 . denotes .
T4169 6054-6180 sentence denotes They then turned laterally towards motor neurons in the lateral motor column, where they branched and terminated (Figure 2A).
T4170 6055-6059 PRP denotes They
T4171 6065-6071 VBD denotes turned
T4172 6060-6064 RB denotes then
T4173 6072-6081 RB denotes laterally
T4174 6082-6089 IN denotes towards
T4175 6090-6095 NN denotes motor
T4176 6096-6103 NNS denotes neurons
T4177 6104-6106 IN denotes in
T4178 6107-6110 DT denotes the
T4179 6125-6131 NN denotes column
T4180 6111-6118 JJ denotes lateral
T4181 6119-6124 NN denotes motor
T4182 6131-6133 , denotes ,
T4183 6133-6138 WRB denotes where
T4184 6144-6152 VBD denotes branched
T4185 6139-6143 PRP denotes they
T4186 6153-6156 CC denotes and
T4187 6157-6167 VBD denotes terminated
T4188 6168-6169 -LRB- denotes (
T4189 6176-6178 NN denotes 2A
T4190 6169-6175 NN denotes Figure
T4191 6178-6179 -RRB- denotes )
T4192 6179-6180 . denotes .
T4193 6180-6386 sentence denotes DiI labeling was confined to dorsal spinal cord in NT-3 KOs (Figure 2A), as reported earlier, consistent with a complete absence of proprioceptive innervation (Ernfors et al. 1994; Tessarollo et al. 1994).
T4194 6181-6184 NN denotes DiI
T4195 6185-6193 NN denotes labeling
T4196 6198-6206 VBN denotes confined
T4197 6194-6197 VBD denotes was
T4198 6207-6209 IN denotes to
T4199 6210-6216 JJ denotes dorsal
T4200 6224-6228 NN denotes cord
T4201 6217-6223 JJ denotes spinal
T4202 6229-6231 IN denotes in
T4203 6232-6234 NN denotes NT
T4204 6237-6240 NNS denotes KOs
T4205 6234-6235 HYPH denotes -
T4206 6235-6236 CD denotes 3
T4207 6241-6242 -LRB- denotes (
T4208 6249-6251 NN denotes 2A
T4209 6242-6248 NN denotes Figure
T4210 6251-6252 -RRB- denotes )
T4211 6252-6254 , denotes ,
T4212 6254-6256 IN denotes as
T4213 6257-6265 VBN denotes reported
T4214 6266-6273 RB denotes earlier
T4215 6273-6275 , denotes ,
T4216 6275-6285 JJ denotes consistent
T4217 6286-6290 IN denotes with
T4218 6291-6292 DT denotes a
T4219 6302-6309 NN denotes absence
T4220 6293-6301 JJ denotes complete
T4221 6310-6312 IN denotes of
T4222 6313-6327 JJ denotes proprioceptive
T4223 6328-6339 NN denotes innervation
T4224 6340-6341 -LRB- denotes (
T4225 6341-6348 NNP denotes Ernfors
T4226 6349-6351 FW denotes et
T4227 6352-6355 FW denotes al.
T4228 6356-6360 CD denotes 1994
T4229 6360-6361 : denotes ;
T4230 6362-6372 NNP denotes Tessarollo
T4231 6373-6375 FW denotes et
T4232 6376-6379 FW denotes al.
T4233 6380-6384 CD denotes 1994
T4234 6384-6385 -RRB- denotes )
T4235 6385-6386 . denotes .
T4236 6386-6596 sentence denotes In double KOs, proprioceptive afferents initially followed a trajectory similar to that of WT counterparts, but most of them failed to project all the way to the ventral cord and into the lateral motor column.
T4237 6387-6389 IN denotes In
T4238 6437-6445 VBD denotes followed
T4239 6390-6396 JJ denotes double
T4240 6397-6400 NNS denotes KOs
T4241 6400-6402 , denotes ,
T4242 6402-6416 JJ denotes proprioceptive
T4243 6417-6426 NNS denotes afferents
T4244 6427-6436 RB denotes initially
T4245 6446-6447 DT denotes a
T4246 6448-6458 NN denotes trajectory
T4247 6459-6466 JJ denotes similar
T4248 6467-6469 IN denotes to
T4249 6470-6474 DT denotes that
T4250 6475-6477 IN denotes of
T4251 6478-6480 NN denotes WT
T4252 6481-6493 NNS denotes counterparts
T4253 6493-6495 , denotes ,
T4254 6495-6498 CC denotes but
T4255 6499-6503 JJS denotes most
T4256 6512-6518 VBD denotes failed
T4257 6504-6506 IN denotes of
T4258 6507-6511 PRP denotes them
T4259 6519-6521 TO denotes to
T4260 6522-6529 VB denotes project
T4261 6530-6533 PDT denotes all
T4262 6538-6541 NN denotes way
T4263 6534-6537 DT denotes the
T4264 6542-6544 IN denotes to
T4265 6545-6548 DT denotes the
T4266 6557-6561 NN denotes cord
T4267 6549-6556 JJ denotes ventral
T4268 6562-6565 CC denotes and
T4269 6566-6570 IN denotes into
T4270 6571-6574 DT denotes the
T4271 6589-6595 NN denotes column
T4272 6575-6582 JJ denotes lateral
T4273 6583-6588 NN denotes motor
T4274 6595-6596 . denotes .
T4275 6596-6740 sentence denotes Instead, they arborized near the ventral midline; some crossed the midline and extended into the contralateral ventral cord (Figure 2A and 2C).
T4276 6597-6604 RB denotes Instead
T4277 6611-6620 VBD denotes arborized
T4278 6604-6606 , denotes ,
T4279 6606-6610 PRP denotes they
T4280 6652-6659 VBD denotes crossed
T4281 6621-6625 IN denotes near
T4282 6626-6629 DT denotes the
T4283 6638-6645 NN denotes midline
T4284 6630-6637 JJ denotes ventral
T4285 6645-6646 : denotes ;
T4286 6647-6651 DT denotes some
T4287 6660-6663 DT denotes the
T4288 6664-6671 NN denotes midline
T4289 6672-6675 CC denotes and
T4290 6676-6684 VBD denotes extended
T4291 6685-6689 IN denotes into
T4292 6690-6693 DT denotes the
T4293 6716-6720 NN denotes cord
T4294 6694-6707 JJ denotes contralateral
T4295 6708-6715 JJ denotes ventral
T4296 6721-6722 -LRB- denotes (
T4297 6729-6731 NN denotes 2A
T4298 6722-6728 NN denotes Figure
T4299 6732-6735 CC denotes and
T4300 6736-6738 NN denotes 2C
T4301 6738-6739 -RRB- denotes )
T4302 6739-6740 . denotes .
T4303 6740-6895 sentence denotes In order to distinguish between a role for NT-3 in initiation of motor neuron innervation and a role for maintenance, we repeated the DiI labeling at E17.
T4304 6741-6743 IN denotes In
T4305 6862-6870 VBD denotes repeated
T4306 6744-6749 NN denotes order
T4307 6750-6752 TO denotes to
T4308 6753-6764 VB denotes distinguish
T4309 6765-6772 IN denotes between
T4310 6773-6774 DT denotes a
T4311 6775-6779 NN denotes role
T4312 6780-6783 IN denotes for
T4313 6784-6786 NN denotes NT
T4314 6786-6787 HYPH denotes -
T4315 6787-6788 CD denotes 3
T4316 6789-6791 IN denotes in
T4317 6792-6802 NN denotes initiation
T4318 6803-6805 IN denotes of
T4319 6806-6811 NN denotes motor
T4320 6812-6818 NN denotes neuron
T4321 6819-6830 NN denotes innervation
T4322 6831-6834 CC denotes and
T4323 6835-6836 DT denotes a
T4324 6837-6841 NN denotes role
T4325 6842-6845 IN denotes for
T4326 6846-6857 NN denotes maintenance
T4327 6857-6859 , denotes ,
T4328 6859-6861 PRP denotes we
T4329 6871-6874 DT denotes the
T4330 6879-6887 NN denotes labeling
T4331 6875-6878 NN denotes DiI
T4332 6888-6890 IN denotes at
T4333 6891-6894 NN denotes E17
T4334 6894-6895 . denotes .
T4335 6895-6987 sentence denotes Innervation patterns of E17 spinal cords (Figure 3) were similar to those at P0 (Figure 2).
T4336 6896-6907 NN denotes Innervation
T4337 6908-6916 NNS denotes patterns
T4338 6948-6952 VBD denotes were
T4339 6917-6919 IN denotes of
T4340 6920-6923 NN denotes E17
T4341 6931-6936 NNS denotes cords
T4342 6924-6930 JJ denotes spinal
T4343 6937-6938 -LRB- denotes (
T4344 6938-6944 NN denotes Figure
T4345 6945-6946 CD denotes 3
T4346 6946-6947 -RRB- denotes )
T4347 6953-6960 JJ denotes similar
T4348 6961-6963 IN denotes to
T4349 6964-6969 DT denotes those
T4350 6970-6972 IN denotes at
T4351 6973-6975 NN denotes P0
T4352 6976-6977 -LRB- denotes (
T4353 6977-6983 NN denotes Figure
T4354 6984-6985 CD denotes 2
T4355 6985-6986 -RRB- denotes )
T4356 6986-6987 . denotes .
T4357 6987-7119 sentence denotes Dorsal horns of all genotypes were filled with DiI-labeled fibers corresponding to nerve growth factor–dependent nociceptive axons.
T4358 6988-6994 JJ denotes Dorsal
T4359 6995-7000 NNS denotes horns
T4360 7023-7029 VBN denotes filled
T4361 7001-7003 IN denotes of
T4362 7004-7007 DT denotes all
T4363 7008-7017 NNS denotes genotypes
T4364 7018-7022 VBD denotes were
T4365 7030-7034 IN denotes with
T4366 7035-7038 NN denotes DiI
T4367 7039-7046 VBN denotes labeled
T4368 7038-7039 HYPH denotes -
T4369 7047-7053 NNS denotes fibers
T4370 7054-7067 VBG denotes corresponding
T4371 7068-7070 IN denotes to
T4372 7071-7076 NN denotes nerve
T4373 7084-7090 NN denotes factor
T4374 7077-7083 NN denotes growth
T4375 7091-7100 JJ denotes dependent
T4376 7090-7091 HYPH denotes –
T4377 7113-7118 NNS denotes axons
T4378 7101-7112 JJ denotes nociceptive
T4379 7118-7119 . denotes .
T4380 7119-7320 sentence denotes In WT and Bax KO embryos, proprioceptive fibers extended towards ventral horn motor neurons (Figure 3A and 3B), whereas the ventral horns of the NT-3 KO embryos were devoid of innervation (Figure 3C).
T4381 7120-7122 IN denotes In
T4382 7168-7176 VBN denotes extended
T4383 7123-7125 NN denotes WT
T4384 7137-7144 NNS denotes embryos
T4385 7126-7129 CC denotes and
T4386 7130-7133 NN denotes Bax
T4387 7134-7136 NN denotes KO
T4388 7144-7146 , denotes ,
T4389 7146-7160 JJ denotes proprioceptive
T4390 7161-7167 NNS denotes fibers
T4391 7177-7184 IN denotes towards
T4392 7185-7192 JJ denotes ventral
T4393 7193-7197 NN denotes horn
T4394 7204-7211 NNS denotes neurons
T4395 7198-7203 NN denotes motor
T4396 7212-7213 -LRB- denotes (
T4397 7220-7222 NN denotes 3A
T4398 7213-7219 NN denotes Figure
T4399 7223-7226 CC denotes and
T4400 7227-7229 NN denotes 3B
T4401 7229-7230 -RRB- denotes )
T4402 7230-7232 , denotes ,
T4403 7232-7239 IN denotes whereas
T4404 7281-7285 VBD denotes were
T4405 7240-7243 DT denotes the
T4406 7252-7257 NNS denotes horns
T4407 7244-7251 JJ denotes ventral
T4408 7258-7260 IN denotes of
T4409 7261-7264 DT denotes the
T4410 7273-7280 NNS denotes embryos
T4411 7265-7267 NN denotes NT
T4412 7270-7272 NN denotes KO
T4413 7267-7268 HYPH denotes -
T4414 7268-7269 CD denotes 3
T4415 7286-7292 JJ denotes devoid
T4416 7293-7295 IN denotes of
T4417 7296-7307 NN denotes innervation
T4418 7308-7309 -LRB- denotes (
T4419 7316-7318 NN denotes 3C
T4420 7309-7315 NN denotes Figure
T4421 7318-7319 -RRB- denotes )
T4422 7319-7320 . denotes .
T4423 7320-7519 sentence denotes In the Bax/NT-3 double KOs, DiI-labeled fibers entered the ventral spinal cord, but extended towards the midline instead of the ventral horn (Figure 3D), in a pattern similar to that observed at P0.
T4424 7321-7323 IN denotes In
T4425 7368-7375 VBD denotes entered
T4426 7324-7327 DT denotes the
T4427 7344-7347 NNS denotes KOs
T4428 7328-7331 NN denotes Bax
T4429 7331-7332 HYPH denotes /
T4430 7332-7334 NN denotes NT
T4431 7334-7335 HYPH denotes -
T4432 7335-7336 CD denotes 3
T4433 7337-7343 JJ denotes double
T4434 7347-7349 , denotes ,
T4435 7349-7352 NN denotes DiI
T4436 7353-7360 VBN denotes labeled
T4437 7352-7353 HYPH denotes -
T4438 7361-7367 NNS denotes fibers
T4439 7376-7379 DT denotes the
T4440 7395-7399 NN denotes cord
T4441 7380-7387 JJ denotes ventral
T4442 7388-7394 JJ denotes spinal
T4443 7399-7401 , denotes ,
T4444 7401-7404 CC denotes but
T4445 7405-7413 VBD denotes extended
T4446 7414-7421 IN denotes towards
T4447 7422-7425 DT denotes the
T4448 7426-7433 NN denotes midline
T4449 7434-7441 RB denotes instead
T4450 7442-7444 IN denotes of
T4451 7445-7448 DT denotes the
T4452 7457-7461 NN denotes horn
T4453 7449-7456 JJ denotes ventral
T4454 7462-7463 -LRB- denotes (
T4455 7470-7472 NN denotes 3D
T4456 7463-7469 NN denotes Figure
T4457 7472-7473 -RRB- denotes )
T4458 7473-7475 , denotes ,
T4459 7475-7477 IN denotes in
T4460 7478-7479 DT denotes a
T4461 7480-7487 NN denotes pattern
T4462 7488-7495 JJ denotes similar
T4463 7496-7498 IN denotes to
T4464 7499-7503 DT denotes that
T4465 7504-7512 VBN denotes observed
T4466 7513-7515 IN denotes at
T4467 7516-7518 NN denotes P0
T4468 7518-7519 . denotes .
T4469 7519-7689 sentence denotes Our data point to a complete absence of proprioceptive innervation of the ventral horn of the Bax/NT-3 null spinal cord throughout the developmental stages investigated.
T4470 7520-7523 PRP$ denotes Our
T4471 7524-7528 NNS denotes data
T4472 7529-7534 VBP denotes point
T4473 7535-7537 IN denotes to
T4474 7538-7539 DT denotes a
T4475 7549-7556 NN denotes absence
T4476 7540-7548 JJ denotes complete
T4477 7557-7559 IN denotes of
T4478 7560-7574 JJ denotes proprioceptive
T4479 7575-7586 NN denotes innervation
T4480 7587-7589 IN denotes of
T4481 7590-7593 DT denotes the
T4482 7602-7606 NN denotes horn
T4483 7594-7601 JJ denotes ventral
T4484 7607-7609 IN denotes of
T4485 7610-7613 DT denotes the
T4486 7635-7639 NN denotes cord
T4487 7614-7617 NN denotes Bax
T4488 7623-7627 JJ denotes null
T4489 7617-7618 HYPH denotes /
T4490 7618-7620 NN denotes NT
T4491 7620-7621 HYPH denotes -
T4492 7621-7622 CD denotes 3
T4493 7628-7634 JJ denotes spinal
T4494 7640-7650 IN denotes throughout
T4495 7651-7654 DT denotes the
T4496 7669-7675 NNS denotes stages
T4497 7655-7668 JJ denotes developmental
T4498 7676-7688 VBN denotes investigated
T4499 7688-7689 . denotes .
T4500 7689-7829 sentence denotes As the sensory axons never reach motor neuron dendrites in the ventral horn (Figure S1), the stretch reflex arc circuit is not established.
T4501 7690-7692 IN denotes As
T4502 7717-7722 VBP denotes reach
T4503 7693-7696 DT denotes the
T4504 7705-7710 NNS denotes axons
T4505 7697-7704 JJ denotes sensory
T4506 7711-7716 RB denotes never
T4507 7817-7828 VBN denotes established
T4508 7723-7728 NN denotes motor
T4509 7729-7735 NN denotes neuron
T4510 7736-7745 NNS denotes dendrites
T4511 7746-7748 IN denotes in
T4512 7749-7752 DT denotes the
T4513 7761-7765 NN denotes horn
T4514 7753-7760 JJ denotes ventral
T4515 7766-7767 -LRB- denotes (
T4516 7774-7776 NN denotes S1
T4517 7767-7773 NN denotes Figure
T4518 7776-7777 -RRB- denotes )
T4519 7777-7779 , denotes ,
T4520 7779-7782 DT denotes the
T4521 7802-7809 NN denotes circuit
T4522 7783-7790 NN denotes stretch
T4523 7791-7797 NN denotes reflex
T4524 7798-7801 NN denotes arc
T4525 7810-7812 VBZ denotes is
T4526 7813-7816 RB denotes not
T4527 7828-7829 . denotes .
T4528 7829-8033 sentence denotes The failure to initiate contact between sensory axons and motor neurons in the absence of NT-3 suggests a requirement for NT-3 for proper axon targeting in addition to a role in sensory axon maintenance.
T4529 7830-7833 DT denotes The
T4530 7834-7841 NN denotes failure
T4531 7925-7933 VBZ denotes suggests
T4532 7842-7844 TO denotes to
T4533 7845-7853 VB denotes initiate
T4534 7854-7861 NN denotes contact
T4535 7862-7869 IN denotes between
T4536 7870-7877 JJ denotes sensory
T4537 7878-7883 NNS denotes axons
T4538 7884-7887 CC denotes and
T4539 7888-7893 NN denotes motor
T4540 7894-7901 NNS denotes neurons
T4541 7902-7904 IN denotes in
T4542 7905-7908 DT denotes the
T4543 7909-7916 NN denotes absence
T4544 7917-7919 IN denotes of
T4545 7920-7922 NN denotes NT
T4546 7922-7923 HYPH denotes -
T4547 7923-7924 CD denotes 3
T4548 7934-7935 DT denotes a
T4566 8021-8032 NN denotes maintenance
T4567 8032-8033 . denotes .
T4549 7936-7947 NN denotes requirement
T4550 7948-7951 IN denotes for
T4551 7952-7954 NN denotes NT
T4552 7954-7955 HYPH denotes -
T4553 7955-7956 CD denotes 3
T4554 7957-7960 IN denotes for
T4555 7961-7967 JJ denotes proper
T4556 7968-7972 NN denotes axon
T4557 7973-7982 VBG denotes targeting
T4558 7983-7985 IN denotes in
T4559 7986-7994 NN denotes addition
T4560 7995-7997 IN denotes to
T4561 7998-7999 DT denotes a
T4562 8000-8004 NN denotes role
T4563 8005-8007 IN denotes in
T4564 8008-8015 JJ denotes sensory
T4565 8016-8020 NN denotes axon
T13995 21508-21511 CC denotes and
T15584 29454-29468 JJ denotes proprioceptive
T15585 29469-29475 NN denotes neuron
T15586 29476-29484 JJ denotes specific
T15587 29475-29476 HYPH denotes -
T15588 29485-29494 NNS denotes receptors
T15589 29495-29502 NNS denotes ligands
T15590 29494-29495 HYPH denotes /
T15591 29503-29506 IN denotes for
T15592 29507-29515 JJ denotes numerous
T15593 29530-29534 NNS denotes cues
T15594 29516-29520 NN denotes axon
T15595 29521-29529 NN denotes guidance
T15596 29534-29535 . denotes .
R1 T428 T423 appos NT,"NT-3 and Proprioceptive Axon Guidance Abstract Neurotrophin"
R2 T429 T428 punct -,NT
R3 T430 T428 nummod 3,NT
R4 T431 T424 punct ),required
R5 T432 T424 auxpass is,required
R6 T433 T424 prep for,required
R7 T434 T435 amod proprioceptive,neuron
R8 T435 T436 compound neuron,survival
R9 T436 T433 pobj survival,for
R10 T437 T424 punct .,required
R11 T439 T440 nsubj Deletion,rescues
R12 T441 T439 prep of,Deletion
R13 T442 T443 det the,gene
R14 T443 T441 pobj gene,of
R15 T444 T443 amod proapoptotic,gene
R16 T445 T443 appos Bax,gene
R17 T446 T439 prep in,Deletion
R18 T447 T448 nmod NT,knockout
R19 T448 T451 compound knockout,mice
R20 T449 T447 punct -,NT
R21 T450 T447 nummod 3,NT
R22 T451 T446 pobj mice,in
R23 T452 T453 det these,neurons
R24 T453 T440 dobj neurons,rescues
R25 T454 T440 cc and,rescues
R26 T455 T440 conj allows,rescues
R27 T456 T455 prep for,allows
R28 T457 T456 pobj examination,for
R29 T458 T457 prep of,examination
R30 T459 T460 poss their,growth
R31 T460 T458 pobj growth,of
R32 T461 T460 compound axon,growth
R33 T462 T455 prep in,allows
R34 T463 T464 det the,absence
R35 T464 T462 pobj absence,in
R36 T465 T464 prep of,absence
R37 T466 T467 nmod NT,signaling
R38 T467 T465 pobj signaling,of
R39 T468 T466 punct -,NT
R40 T469 T466 nummod 3,NT
R41 T470 T440 punct .,rescues
R42 T472 T473 npadvmod TrkC,positive
R43 T473 T475 amod positive,axons
R44 T474 T473 punct -,positive
R45 T475 T479 nsubj axons,follow
R46 T476 T475 amod peripheral,axons
R47 T477 T476 cc and,peripheral
R48 T478 T476 conj central,peripheral
R49 T480 T475 prep from,axons
R50 T481 T482 amod dorsal,root
R51 T482 T483 compound root,ganglia
R52 T483 T480 pobj ganglia,from
R53 T484 T485 amod proper,trajectories
R54 T485 T479 dobj trajectories,follow
R55 T486 T479 cc and,follow
R56 T487 T479 conj arrive,follow
R57 T488 T487 prep in,arrive
R58 T489 T490 amod close,proximity
R59 T490 T488 pobj proximity,in
R60 T491 T490 prep to,proximity
R61 T492 T493 poss their,targets
R62 T493 T491 pobj targets,to
R65 T408 T409 det A,Role
R66 T411 T409 compound Chemoattractant,Role
R67 T412 T409 prep for,Role
R68 T413 T412 pobj NT,for
R69 T414 T413 punct -,NT
R70 T415 T413 nummod 3,NT
R71 T416 T409 prep in,Role
R72 T417 T418 compound Proprioceptive,Axon
R73 T418 T419 compound Axon,Guidance
R74 T419 T416 pobj Guidance,in
R75 T423 T424 nsubjpass "NT-3 and Proprioceptive Axon Guidance Abstract Neurotrophin",required
R76 T425 T423 punct -,"NT-3 and Proprioceptive Axon Guidance Abstract Neurotrophin"
R77 T426 T423 nummod 3,"NT-3 and Proprioceptive Axon Guidance Abstract Neurotrophin"
R78 T427 T423 punct (,"NT-3 and Proprioceptive Axon Guidance Abstract Neurotrophin"
R79 T494 T479 cc but,follow
R80 T495 T479 conj fail,follow
R81 T496 T497 aux to,innervate
R82 T497 T495 xcomp innervate,fail
R83 T498 T497 dobj them,innervate
R84 T499 T479 punct .,follow
R85 T501 T502 advmod Peripherally,are
R86 T503 T502 punct ", ",are
R87 T504 T505 compound muscle,spindles
R88 T505 T502 nsubj spindles,are
R89 T506 T502 acomp absent,are
R90 T507 T502 cc and,are
R91 T508 T509 npadvmod TrkC,positive
R92 T509 T511 amod positive,axons
R93 T510 T509 punct -,positive
R94 T511 T512 nsubj axons,enter
R96 T513 T512 aux do,enter
R97 T514 T512 neg not,enter
R98 T515 T516 poss their,muscles
R99 T516 T512 dobj muscles,enter
R100 T517 T516 compound target,muscles
R101 T518 T502 punct .,are
R102 T520 T521 advmod Centrally,branch
R103 T522 T521 punct ", ",branch
R104 T523 T524 amod proprioceptive,axons
R105 T524 T521 nsubj axons,branch
R106 T525 T521 prep in,branch
R107 T526 T527 amod ectopic,regions
R108 T527 T525 pobj regions,in
R109 T528 T527 prep of,regions
R110 T529 T530 det the,cord
R111 T530 T528 pobj cord,of
R112 T531 T530 amod spinal,cord
R113 T532 T521 punct ", ",branch
R114 T533 T534 advmod even,crossing
R115 T534 T521 advcl crossing,branch
R116 T535 T536 det the,midline
R117 T536 T534 dobj midline,crossing
R118 T537 T521 punct .,branch
R119 T539 T540 advmod In,vitro
R120 T540 T541 amod vitro,assays
R121 T541 T542 nsubj assays,reveal
R122 T543 T544 compound chemoattractant,effects
R123 T544 T542 dobj effects,reveal
R124 T545 T544 prep of,effects
R125 T546 T545 pobj NT,of
R126 T547 T546 punct -,NT
R127 T548 T546 nummod 3,NT
R128 T549 T544 prep on,effects
R129 T550 T551 amod dorsal,root
R130 T551 T552 compound root,ganglion
R131 T552 T553 compound ganglion,axons
R132 T553 T549 pobj axons,on
R133 T554 T542 punct .,reveal
R134 T556 T557 poss Our,results
R135 T557 T558 nsubj results,show
R136 T559 T560 mark that,acts
R137 T560 T558 ccomp acts,show
R138 T561 T562 compound survival,factor
R139 T562 T563 compound factor,NT
R140 T563 T560 nsubj NT,acts
R141 T564 T563 punct -,NT
R142 T565 T563 nummod 3,NT
R143 T566 T560 prep as,acts
R144 T567 T568 det a,molecule
R145 T568 T566 pobj molecule,as
R146 T569 T570 amod short,distance
R147 T570 T568 compound distance,molecule
R148 T571 T570 punct -,distance
R149 T572 T573 compound axon,guidance
R150 T573 T568 compound guidance,molecule
R151 T574 T560 prep for,acts
R152 T575 T576 compound muscle,afferents
R153 T576 T574 pobj afferents,for
R154 T577 T576 compound sensory,afferents
R155 T578 T579 mark as,approach
R156 T579 T560 advcl approach,acts
R157 T580 T579 nsubj they,approach
R158 T581 T582 poss their,targets
R159 T582 T579 dobj targets,approach
R160 T583 T582 amod proper,targets
R161 T584 T558 punct .,show
R162 T1178 T1179 nsubj Neurotrophin,is
R163 T1180 T1178 punct -,Neurotrophin
R164 T1181 T1178 nummod 3,Neurotrophin
R165 T1182 T1178 punct (,Neurotrophin
R166 T1183 T1178 appos NT,Neurotrophin
R167 T1184 T1183 punct -,NT
R168 T1185 T1183 nummod 3,NT
R169 T1186 T1179 punct ),is
R170 T1187 T1188 det a,requirement
R171 T1188 T1179 attr requirement,is
R172 T1189 T1188 amod key,requirement
R173 T1190 T1188 prep for,requirement
R174 T1191 T1192 det the,development
R175 T1192 T1190 pobj development,for
R176 T1193 T1192 prep of,development
R177 T1194 T1195 amod proprioceptive,inputs
R178 T1195 T1193 pobj inputs,of
R179 T1196 T1195 prep to,inputs
R180 T1197 T1198 amod motor,neurons
R181 T1198 T1196 pobj neurons,to
R182 T1199 T1200 punct (,Chen
R183 T1200 T1179 meta Chen,is
R184 T1201 T1200 cc and,Chen
R185 T1202 T1200 conj Frank,Chen
R186 T1203 T1202 nummod 1999,Frank
R187 T1204 T1202 punct ;,Frank
R188 T1205 T1202 conj Chen,Frank
R189 T1206 T1205 nmod et,Chen
R190 T1207 T1205 nmod al.,Chen
R191 T1208 T1205 nummod 2003,Chen
R192 T1209 T1205 punct ),Chen
R193 T1210 T1179 punct .,is
R194 T1212 T1213 nsubj Mice,display
R195 T1214 T1212 amod deficient,Mice
R196 T1215 T1214 prep in,deficient
R197 T1216 T1215 pobj NT,in
R198 T1217 T1216 punct -,NT
R199 T1218 T1216 nummod 3,NT
R200 T1219 T1216 punct ", ",NT
R201 T1220 T1221 poss its,receptor
R203 T1222 T1221 compound tyrosine,receptor
R204 T1223 T1221 compound kinase,receptor
R205 T1224 T1221 punct ", ",receptor
R206 T1225 T1221 appos TrkC,receptor
R207 T1226 T1215 punct ", ",in
R208 T1227 T1215 cc or,in
R209 T1228 T1215 conj in,in
R210 T1229 T1230 npadvmod TrkC,positive
R211 T1230 T1232 amod positive,factor
R212 T1231 T1230 punct -,positive
R213 T1232 T1237 compound factor,Runx3
R214 T1233 T1232 nmod neuron,factor
R215 T1234 T1233 punct -,neuron
R216 T1235 T1233 amod specific,neuron
R217 T1236 T1232 compound transcription,factor
R218 T1237 T1228 pobj Runx3,in
R219 T1238 T1239 amod severe,ataxia
R220 T1239 T1213 dobj ataxia,display
R221 T1240 T1239 acl associated,ataxia
R222 T1241 T1240 prep with,associated
R223 T1242 T1243 det the,absence
R224 T1243 T1241 pobj absence,with
R225 T1244 T1243 prep of,absence
R226 T1245 T1246 compound muscle,spindles
R227 T1246 T1244 pobj spindles,of
R228 T1247 T1239 punct ", ",ataxia
R229 T1248 T1239 cc and,ataxia
R230 T1249 T1239 conj loss,ataxia
R231 T1250 T1249 prep of,loss
R232 T1251 T1252 amod proprioceptive,neurons
R233 T1252 T1250 pobj neurons,of
R234 T1253 T1252 prep in,neurons
R235 T1254 T1255 amod dorsal,root
R236 T1255 T1256 compound root,ganglia
R237 T1256 T1253 pobj ganglia,in
R238 T1257 T1256 punct (,ganglia
R239 T1258 T1256 appos DRGs,ganglia
R240 T1259 T1256 punct ),ganglia
R241 T1260 T1256 cc or,ganglia
R242 T1261 T1262 poss their,axons
R243 T1262 T1256 conj axons,ganglia
R244 T1263 T1264 punct (,Ernfors
R245 T1264 T1213 meta Ernfors,display
R246 T1265 T1264 nmod et,Ernfors
R247 T1266 T1264 nmod al.,Ernfors
R248 T1267 T1264 nummod 1994,Ernfors
R249 T1268 T1264 punct ;,Ernfors
R250 T1269 T1264 nmod Klein,Ernfors
R251 T1270 T1264 nmod et,Ernfors
R252 T1271 T1264 nmod al.,Ernfors
R253 T1272 T1264 nummod 1994,Ernfors
R254 T1273 T1264 punct ;,Ernfors
R255 T1274 T1264 nmod Tessarollo,Ernfors
R256 T1275 T1264 nmod et,Ernfors
R257 T1276 T1264 nmod al.,Ernfors
R258 T1277 T1264 nummod 1994,Ernfors
R259 T1278 T1264 punct ;,Ernfors
R260 T1279 T1264 nmod Fariñas,Ernfors
R261 T1280 T1264 nmod et,Ernfors
R262 T1281 T1264 nmod al.,Ernfors
R263 T1282 T1264 nummod 1996,Ernfors
R264 T1283 T1264 punct ;,Ernfors
R265 T1284 T1264 nmod Liebl,Ernfors
R266 T1285 T1264 nmod et,Ernfors
R267 T1286 T1264 nmod al.,Ernfors
R268 T1287 T1264 nummod 1997,Ernfors
R269 T1288 T1264 punct ;,Ernfors
R270 T1289 T1264 nmod Inoue,Ernfors
R271 T1290 T1264 nmod et,Ernfors
R272 T1291 T1264 nmod al.,Ernfors
R273 T1292 T1264 nummod 2002,Ernfors
R274 T1293 T1264 punct ;,Ernfors
R275 T1294 T1264 nmod Levanon,Ernfors
R276 T1295 T1264 nmod et,Ernfors
R277 T1296 T1264 nmod al.,Ernfors
R278 T1297 T1264 nummod 2002,Ernfors
R279 T1298 T1264 punct ),Ernfors
R280 T1299 T1213 punct .,display
R281 T1301 T1302 nsubjpass NT,expressed
R282 T1303 T1301 punct -,NT
R283 T1304 T1301 nummod 3,NT
R284 T1305 T1302 auxpass is,expressed
R285 T1306 T1302 prep in,expressed
R286 T1307 T1308 det the,cord
R288 T1309 T1308 amod ventral,cord
R289 T1310 T1308 amod spinal,cord
R290 T1311 T1306 punct ", ",in
R291 T1312 T1306 conj in,in
R292 T1313 T1314 det the,buds
R294 T1315 T1314 amod developing,buds
R295 T1316 T1314 compound limb,buds
R296 T1317 T1312 punct ", ",in
R297 T1318 T1312 cc and,in
R298 T1319 T1312 conj in,in
R299 T1320 T1321 amod intrafusal,fibers
R300 T1321 T1319 pobj fibers,in
R301 T1322 T1321 compound bag,fibers
R302 T1323 T1321 prep of,fibers
R303 T1324 T1325 compound muscle,spindles
R304 T1325 T1323 pobj spindles,of
R305 T1326 T1302 advmod later,expressed
R306 T1327 T1326 prep in,later
R307 T1328 T1327 pobj development,in
R308 T1329 T1330 punct (,Copray
R309 T1330 T1302 meta Copray,expressed
R310 T1331 T1330 cc and,Copray
R311 T1332 T1330 conj Brouwer,Copray
R312 T1333 T1332 nummod 1994,Brouwer
R313 T1334 T1332 punct ;,Brouwer
R314 T1335 T1332 conj Fariñas,Brouwer
R315 T1336 T1335 nmod et,Fariñas
R316 T1337 T1335 nmod al.,Fariñas
R317 T1338 T1335 nummod 1996,Fariñas
R318 T1339 T1335 punct ;,Fariñas
R319 T1340 T1335 conj Tojo,Fariñas
R320 T1341 T1340 nmod et,Tojo
R321 T1342 T1340 nmod al.,Tojo
R322 T1343 T1340 nummod 1996,Tojo
R323 T1344 T1340 punct ),Tojo
R324 T1345 T1302 punct .,expressed
R325 T1347 T1348 advmod When,contact
R327 T1349 T1350 amod sensory,axons
R328 T1350 T1348 nsubj axons,contact
R329 T1352 T1353 amod developing,myotubes
R330 T1353 T1348 dobj myotubes,contact
R331 T1354 T1351 punct ", ",induce
R332 T1355 T1351 nsubj they,induce
R333 T1356 T1357 compound muscle,spindle
R334 T1357 T1358 compound spindle,differentiation
R335 T1358 T1351 dobj differentiation,induce
R336 T1359 T1351 punct ", ",induce
R337 T1360 T1351 advcl forming,induce
R338 T1361 T1362 npadvmod ring,like
R339 T1362 T1364 amod like,endings
R340 T1363 T1362 punct -,like
R342 T1365 T1364 amod spiral,endings
R343 T1366 T1364 compound nerve,endings
R344 T1367 T1360 prep around,forming
R345 T1368 T1367 pobj them,around
R346 T1369 T1351 punct .,induce
R347 T1371 T1372 prep In,lead
R348 T1373 T1374 det the,embryo
R349 T1374 T1371 pobj embryo,In
R350 T1375 T1374 compound chicken,embryo
R351 T1376 T1372 punct ", ",lead
R352 T1377 T1378 compound limb,ablations
R353 T1378 T1372 nsubj ablations,lead
R354 T1379 T1378 cc or,ablations
R355 T1380 T1381 amod anti-NT,3
R356 T1381 T1383 nummod 3,antibody
R357 T1382 T1381 punct -,3
R358 T1383 T1384 compound antibody,injections
R359 T1384 T1378 conj injections,ablations
R360 T1385 T1384 prep into,injections
R361 T1386 T1387 compound limb,buds
R362 T1387 T1385 pobj buds,into
R363 T1388 T1372 prep to,lead
R364 T1389 T1388 pobj elimination,to
R365 T1390 T1389 prep of,elimination
R366 T1391 T1392 npadvmod TrkC,positive
R367 T1392 T1394 amod positive,neurons
R368 T1393 T1392 punct -,positive
R369 T1394 T1390 pobj neurons,of
R370 T1395 T1389 cc and,elimination
R371 T1396 T1397 amod decreased,innervation
R372 T1397 T1389 conj innervation,elimination
R373 T1398 T1397 prep of,innervation
R374 T1399 T1400 compound motor,neurons
R375 T1400 T1398 pobj neurons,of
R376 T1401 T1402 punct (,Oakley
R377 T1402 T1372 meta Oakley,lead
R378 T1403 T1402 nmod et,Oakley
R379 T1404 T1402 nmod al.,Oakley
R380 T1405 T1402 nummod 1995,Oakley
R381 T1406 T1402 punct ", ",Oakley
R382 T1407 T1402 nummod 1997,Oakley
R383 T1408 T1402 punct ),Oakley
R384 T1409 T1372 punct .,lead
R385 T1412 T1411 nsubj NT,Is
R386 T1413 T1412 punct -,NT
R387 T1414 T1412 nummod 3,NT
R388 T1415 T1416 advmod only,factor
R389 T1416 T1411 attr factor,Is
R390 T1417 T1416 det a,factor
R391 T1418 T1416 amod chemotrophic,factor
R392 T1419 T1416 compound survival,factor
R393 T1420 T1416 prep for,factor
R394 T1421 T1422 nmod muscle,afferents
R395 T1422 T1420 pobj afferents,for
R396 T1423 T1422 amod sensory,afferents
R397 T1424 T1411 punct ", ",Is
R398 T1425 T1411 cc or,Is
R399 T1426 T1427 aux does,have
R400 T1427 T1411 conj have,Is
R401 T1428 T1427 nsubj it,have
R402 T1429 T1430 amod additional,roles
R403 T1430 T1427 dobj roles,have
R404 T1431 T1430 prep in,roles
R405 T1432 T1433 det the,development
R406 T1433 T1431 pobj development,in
R407 T1434 T1433 prep of,development
R408 T1435 T1436 det the,proprioceptors
R409 T1436 T1434 pobj proprioceptors,of
R410 T1437 T1433 cc and,development
R411 T1438 T1439 det the,establishment
R412 T1439 T1433 conj establishment,development
R413 T1440 T1439 prep of,establishment
R414 T1441 T1442 det the,arc
R416 T1443 T1442 amod monosynaptic,arc
R417 T1444 T1442 compound reflex,arc
R418 T1445 T1427 punct ?,have
R419 T1447 T1448 advmod Here,provide
R420 T1449 T1448 nsubj we,provide
R421 T1450 T1448 dobj evidence,provide
R422 T1451 T1452 mark that,acts
R423 T1452 T1450 acl acts,evidence
R424 T1453 T1452 nsubj NT,acts
R425 T1454 T1453 punct -,NT
R426 T1455 T1453 nummod 3,NT
R427 T1456 T1452 prep as,acts
R428 T1457 T1458 det a,chemoattractant
R429 T1458 T1456 pobj chemoattractant,as
R430 T1459 T1458 prep for,chemoattractant
R431 T1460 T1461 amod sensory,axons
R432 T1461 T1459 pobj axons,for
R433 T1462 T1452 prep during,acts
R434 T1463 T1464 det the,phase
R435 T1464 T1462 pobj phase,during
R436 T1465 T1464 amod final,phase
R437 T1466 T1464 prep of,phase
R438 T1467 T1468 poss their,pathfinding
R439 T1468 T1466 pobj pathfinding,of
R440 T1469 T1470 npadvmod target,directed
R441 T1470 T1468 amod directed,pathfinding
R442 T1471 T1470 punct -,directed
R443 T1472 T1448 punct .,provide
R444 T2324 T2325 npadvmod TrkC,Positive
R445 T2325 T2327 amod Positive,Neurons
R446 T2326 T2325 punct -,Positive
R447 T2327 T2329 nsubjpass Neurons,Rescued
R448 T2328 T2327 compound DRG,Neurons
R449 T2330 T2329 auxpass Are,Rescued
R450 T2331 T2329 prep in,Rescued
R451 T2332 T2333 nmod Bax,Knockout
R452 T2333 T2339 compound Knockout,Mice
R453 T2334 T2332 punct /,Bax
R454 T2335 T2332 appos NT,Bax
R455 T2336 T2335 punct -,NT
R456 T2337 T2335 nummod 3,NT
R457 T2338 T2333 amod Double,Knockout
R458 T2339 T2331 pobj Mice,in
R459 T2341 T2342 nsubj Mice,allow
R460 T2343 T2341 acl lacking,Mice
R461 T2344 T2345 amod proapoptotic,Bax
R462 T2345 T2343 dobj Bax,lacking
R463 T2346 T2345 compound protein,Bax
R464 T2347 T2342 prep for,allow
R465 T2348 T2347 pcomp distinguishing,for
R466 T2349 T2350 compound survival,effects
R467 T2350 T2348 dobj effects,distinguishing
R468 T2351 T2350 prep of,effects
R469 T2352 T2351 pobj neurotrophins,of
R470 T2353 T2348 prep from,distinguishing
R471 T2354 T2355 amod other,effects
R472 T2355 T2353 pobj effects,from
R473 T2356 T2342 punct .,allow
R474 T2358 T2359 npadvmod Bax,deficient
R475 T2359 T2361 amod deficient,neurons
R476 T2360 T2359 punct -,deficient
R477 T2361 T2363 nsubj neurons,require
R478 T2362 T2361 amod sensory,neurons
R480 T2364 T2365 neg no,longer
R481 T2365 T2363 advmod longer,require
R482 T2367 T2363 dobj neurotrophins,require
R483 T2368 T2363 prep for,require
R484 T2369 T2368 pobj survival,for
R485 T2370 T2371 punct (,White
R486 T2371 T2363 meta White,require
R487 T2372 T2371 nmod et,White
R488 T2373 T2371 nmod al.,White
R489 T2374 T2371 nummod 1998,White
R490 T2375 T2371 punct ;,White
R491 T2376 T2371 nmod Patel,White
R492 T2377 T2371 nmod et,White
R493 T2378 T2371 nmod al.,White
R494 T2379 T2371 nummod 2000,White
R495 T2380 T2371 punct ),White
R496 T2381 T2366 punct ", ",used
R497 T2382 T2366 advmod thus,used
R498 T2383 T2366 nsubjpass they,used
R499 T2384 T2366 aux can,used
R500 T2385 T2366 auxpass be,used
R501 T2386 T2387 aux to,examine
R502 T2387 T2366 advcl examine,used
R503 T2388 T2389 amod axonal,effects
R504 T2389 T2387 dobj effects,examine
R505 T2390 T2366 punct .,used
R506 T2392 T2393 nsubj We,bred
R507 T2394 T2395 nmod NT,heterozygote
R509 T2396 T2394 punct -,NT
R510 T2397 T2394 nummod 3,NT
R511 T2398 T2395 cc and,heterozygote
R512 T2399 T2400 nmod Bax,knockout
R513 T2400 T2401 nmod knockout,mice
R514 T2401 T2395 conj mice,heterozygote
R515 T2402 T2400 punct (,knockout
R516 T2403 T2400 appos KO,knockout
R517 T2404 T2401 punct ),mice
R518 T2405 T2406 aux to,obtain
R519 T2406 T2393 advcl obtain,bred
R520 T2407 T2406 dobj mice,obtain
R521 T2408 T2407 prep with,mice
R522 T2409 T2410 amod double,KO
R523 T2410 T2408 pobj KO,with
R524 T2411 T2410 prep of,KO
R525 T2412 T2413 preconj both,NT
R526 T2413 T2414 nmod NT,genes
R527 T2414 T2411 pobj genes,of
R528 T2415 T2413 punct -,NT
R529 T2416 T2413 nummod 3,NT
R530 T2417 T2413 cc and,NT
R531 T2418 T2413 conj Bax,NT
R532 T2419 T2393 punct ", ",bred
R533 T2420 T2393 cc and,bred
R534 T2421 T2393 conj examined,bred
R535 T2422 T2423 amod proprioceptive,projections
R536 T2423 T2421 dobj projections,examined
R537 T2424 T2423 amod axonal,projections
R538 T2425 T2393 punct .,bred
R539 T2427 T2428 det All,KOs
R540 T2428 T2434 nsubj KOs,died
R541 T2429 T2428 nmod NT,KOs
R542 T2430 T2429 punct -,NT
R543 T2431 T2429 nummod 3,NT
R544 T2432 T2429 cc and,NT
R545 T2433 T2429 conj double,NT
R546 T2435 T2434 prep within,died
R547 T2436 T2437 nummod 48,h
R548 T2437 T2435 pobj h,within
R549 T2438 T2437 prep after,h
R550 T2439 T2438 pobj birth,after
R551 T2440 T2441 punct (,Tessarollo
R552 T2441 T2434 meta Tessarollo,died
R553 T2442 T2441 nmod et,Tessarollo
R554 T2443 T2441 nmod al.,Tessarollo
R555 T2444 T2441 nummod 1994,Tessarollo
R556 T2445 T2441 punct ),Tessarollo
R557 T2446 T2434 punct .,died
R558 T2448 T2449 nsubj We,performed
R559 T2450 T2451 nmod TrkA,TrkC
R560 T2451 T2453 nmod TrkC,immunohistochemistry
R561 T2452 T2451 punct /,TrkC
R562 T2453 T2449 dobj immunohistochemistry,performed
R563 T2454 T2453 amod double,immunohistochemistry
R564 T2455 T2456 punct (,Huang
R565 T2456 T2453 meta Huang,immunohistochemistry
R566 T2457 T2456 nmod et,Huang
R567 T2458 T2456 nmod al.,Huang
R568 T2459 T2456 nummod 1999,Huang
R569 T2460 T2456 punct ),Huang
R570 T2461 T2449 punct ", ",performed
R571 T2462 T2449 advcl enabling,performed
R572 T2463 T2462 dobj detection,enabling
R573 T2464 T2463 prep of,detection
R574 T2465 T2466 det both,proteins
R575 T2466 T2464 pobj proteins,of
R576 T2467 T2462 prep in,enabling
R577 T2468 T2469 det the,sample
R578 T2469 T2467 pobj sample,in
R579 T2470 T2469 amod same,sample
R580 T2471 T2449 punct .,performed
R581 T2473 T2474 npadvmod TrkC,positive
R582 T2474 T2476 amod positive,cells
R583 T2475 T2474 punct -,positive
R584 T2476 T2477 nsubj cells,were
R585 T2478 T2479 punct (,1A
R586 T2479 T2476 parataxis 1A,cells
R587 T2480 T2479 compound Figure,1A
R588 T2481 T2479 punct ),1A
R589 T2482 T2476 cc and,cells
R590 T2483 T2476 conj fibers,cells
R591 T2484 T2485 punct (,1E
R592 T2485 T2483 parataxis 1E,fibers
R593 T2486 T2485 compound Figure,1E
R594 T2487 T2485 punct ),1E
R595 T2488 T2477 acomp absent,were
R596 T2489 T2477 prep in,were
R597 T2490 T2491 nmod NT,KOs
R599 T2492 T2490 punct -,NT
R600 T2493 T2490 nummod 3,NT
R601 T2494 T2477 prep at,were
R602 T2495 T2496 amod embryonic,day
R603 T2496 T2494 pobj day,at
R604 T2497 T2496 punct (,day
R605 T2498 T2496 appos E,day
R606 T2499 T2496 punct ),day
R607 T2500 T2496 nummod 15,day
R608 T2501 T2477 punct .,were
R609 T2503 T2504 nummod Two,subsets
R610 T2504 T2505 nsubjpass subsets,detected
R611 T2506 T2504 prep of,subsets
R612 T2507 T2508 compound DRG,cells
R613 T2508 T2506 pobj cells,of
R614 T2509 T2504 acl expressing,subsets
R615 T2510 T2511 preconj either,TrkA
R616 T2511 T2509 dobj TrkA,expressing
R617 T2512 T2511 cc or,TrkA
R618 T2513 T2511 conj TrkC,TrkA
R619 T2514 T2505 auxpass were,detected
R620 T2515 T2505 prep in,detected
R621 T2516 T2517 amod double,KOs
R622 T2517 T2515 pobj KOs,in
R623 T2518 T2505 punct ", ",detected
R624 T2519 T2505 advcl similar,detected
R625 T2520 T2519 prep to,similar
R626 T2521 T2522 amod wild,type
R627 T2522 T2524 nmod type,animals
R628 T2523 T2522 punct -,type
R629 T2524 T2520 pobj animals,to
R630 T2525 T2522 punct (,type
R631 T2526 T2522 appos WT,type
R632 T2527 T2522 punct ),type
R633 T2528 T2522 cc or,type
R634 T2529 T2530 compound Bax,KO
R635 T2530 T2522 conj KO,type
R636 T2531 T2505 punct .,detected
R637 T2533 T2534 advmod Surprisingly,expressed
R638 T2535 T2534 punct ", ",expressed
R639 T2536 T2534 prep at,expressed
R640 T2537 T2538 amod postnatal,day
R641 T2538 T2536 pobj day,at
R642 T2539 T2538 punct (,day
R643 T2540 T2538 appos P,day
R644 T2541 T2538 punct ),day
R645 T2542 T2538 nummod 0,day
R646 T2543 T2534 punct ", ",expressed
R647 T2544 T2545 det a,cells
R648 T2545 T2534 nsubj cells,expressed
R649 T2546 T2545 amod few,cells
R650 T2547 T2534 dobj TrkC,expressed
R651 T2548 T2549 advmod even,in
R652 T2549 T2534 prep in,expressed
R653 T2550 T2551 nmod NT,KO
R655 T2552 T2550 punct -,NT
R656 T2553 T2550 nummod 3,NT
R657 T2554 T2549 pobj animals,in
R658 T2555 T2554 prep in,animals
R659 T2556 T2557 det the,background
R660 T2557 T2555 pobj background,in
R661 T2558 T2557 nmod Bax,background
R662 T2559 T2558 punct +,Bax
R663 T2560 T2558 punct /,Bax
R664 T2561 T2558 punct +,Bax
R665 T2562 T2557 amod genetic,background
R666 T2563 T2534 punct ", ",expressed
R667 T2564 T2534 cc and,expressed
R668 T2565 T2566 det some,cells
R669 T2566 T2567 nsubj cells,co-expressed
R670 T2567 T2534 conj co-expressed,expressed
R671 T2568 T2567 dobj TrkA,co-expressed
R672 T2569 T2568 cc and,TrkA
R673 T2570 T2568 conj TrkC,TrkA
R674 T2571 T2567 punct ", ",co-expressed
R675 T2572 T2567 advmod regardless,co-expressed
R676 T2573 T2572 prep of,regardless
R677 T2574 T2575 det the,genotype
R678 T2575 T2573 pobj genotype,of
R679 T2576 T2577 punct (,1B
R680 T2577 T2567 parataxis 1B,co-expressed
R681 T2578 T2577 compound Figure,1B
R682 T2579 T2577 punct ),1B
R683 T2580 T2534 punct .,expressed
R684 T2582 T2583 prep In,analyzed
R685 T2584 T2582 pobj order,In
R686 T2585 T2586 aux to,quantify
R687 T2586 T2584 acl quantify,order
R688 T2587 T2588 poss our,results
R689 T2588 T2586 dobj results,quantify
R690 T2589 T2583 punct ", ",analyzed
R691 T2590 T2583 nsubj we,analyzed
R692 T2591 T2592 det the,ratio
R693 T2592 T2583 dobj ratio,analyzed
R694 T2593 T2592 prep of,ratio
R695 T2594 T2595 npadvmod TrkA,immunopositive
R697 T2596 T2594 cc and,TrkA
R698 T2597 T2594 conj TrkC,TrkA
R699 T2598 T2593 pobj cells,of
R700 T2599 T2598 prep from,cells
R701 T2600 T2601 nummod four,DRGs
R702 T2601 T2599 pobj DRGs,from
R703 T2602 T2601 amod different,DRGs
R704 T2603 T2601 prep of,DRGs
R705 T2604 T2603 pobj animals,of
R706 T2605 T2604 prep of,animals
R707 T2606 T2607 amod different,genotypes
R708 T2607 T2605 pobj genotypes,of
R709 T2608 T2583 punct .,analyzed
R710 T2610 T2611 prep At,had
R711 T2612 T2613 det all,ages
R712 T2613 T2610 pobj ages,At
R713 T2614 T2613 acl studied,ages
R714 T2615 T2611 punct ", ",had
R715 T2616 T2617 npadvmod Bax,null
R716 T2617 T2623 amod null,DRGs
R717 T2618 T2616 punct /,Bax
R718 T2619 T2616 appos NT,Bax
R719 T2620 T2619 punct -,NT
R720 T2621 T2619 nummod 3,NT
R721 T2622 T2617 amod double,null
R722 T2623 T2611 nsubj DRGs,had
R723 T2624 T2625 compound TrkA,TrkC
R724 T2625 T2627 compound TrkC,ratios
R725 T2626 T2625 punct /,TrkC
R726 T2627 T2611 dobj ratios,had
R727 T2628 T2627 amod similar,ratios
R728 T2629 T2628 prep to,similar
R729 T2630 T2629 pobj those,to
R730 T2631 T2630 prep of,those
R731 T2632 T2633 npadvmod Bax,null
R732 T2633 T2634 amod null,DRGs
R733 T2634 T2631 pobj DRGs,of
R734 T2635 T2628 punct ", ",similar
R735 T2636 T2628 cc and,similar
R736 T2637 T2628 conj higher,similar
R737 T2638 T2637 prep than,higher
R738 T2639 T2638 pobj those,than
R739 T2640 T2639 prep of,those
R740 T2641 T2642 npadvmod NT,null
R742 T2643 T2641 punct -,NT
R743 T2644 T2641 nummod 3,NT
R744 T2645 T2640 pobj DRGs,of
R745 T2646 T2647 punct (,1D
R746 T2647 T2611 parataxis 1D,had
R747 T2648 T2647 compound Figure,1D
R748 T2649 T2647 punct ),1D
R749 T2650 T2611 punct .,had
R750 T2652 T2653 npadvmod TrkC,positive
R751 T2653 T2655 amod positive,neurons
R752 T2654 T2653 punct -,positive
R753 T2655 T2656 nsubj neurons,failed
R754 T2657 T2655 acl rescued,neurons
R755 T2658 T2657 prep by,rescued
R756 T2659 T2660 compound Bax,deletion
R757 T2660 T2658 pobj deletion,by
R758 T2661 T2656 punct ", ",failed
R759 T2662 T2656 advmod however,failed
R760 T2663 T2656 punct ", ",failed
R761 T2664 T2665 aux to,differentiate
R762 T2665 T2656 xcomp differentiate,failed
R763 T2666 T2665 advmod properly,differentiate
R764 T2667 T2665 punct ", ",differentiate
R765 T2668 T2669 mark as,evidenced
R766 T2669 T2665 advcl evidenced,differentiate
R767 T2670 T2669 prep by,evidenced
R768 T2671 T2672 det the,lack
R769 T2672 T2670 pobj lack,by
R770 T2673 T2672 prep of,lack
R771 T2674 T2673 pobj expression,of
R772 T2675 T2674 prep of,expression
R773 T2676 T2677 det the,marker
R775 T2678 T2677 amod proprioceptive,marker
R776 T2679 T2677 amod molecular,marker
R777 T2680 T2677 appos Parvalbumin,marker
R778 T2681 T2677 punct (,marker
R779 T2682 T2677 appos PV,marker
R780 T2683 T2656 punct ),failed
R781 T2684 T2685 punct (,1C
R782 T2685 T2656 parataxis 1C,failed
R783 T2686 T2685 compound Figure,1C
R784 T2687 T2685 punct ),1C
R785 T2688 T2656 punct .,failed
R790 T3969 T3970 nsubj NT,Is
R791 T3971 T3969 punct -,NT
R792 T3972 T3969 nummod 3,NT
R793 T3973 T3970 acomp Necessary,Is
R794 T3974 T3973 prep for,Necessary
R795 T3975 T3976 amod Proper,Innervation
R796 T3976 T3974 pobj Innervation,for
R797 T3977 T3976 prep of,Innervation
R798 T3978 T3979 amod Motor,Neurons
R799 T3979 T3977 pobj Neurons,of
R800 T3981 T3982 compound TrkA,TrkC
R801 T3982 T3984 npadvmod TrkC,positive
R802 T3983 T3982 punct /,TrkC
R803 T3984 T3986 amod positive,fibers
R804 T3985 T3984 punct -,positive
R805 T3986 T3987 nsubjpass fibers,detected
R806 T3988 T3986 prep in,fibers
R807 T3989 T3990 det the,cord
R808 T3990 T3988 pobj cord,in
R809 T3991 T3990 amod spinal,cord
R810 T3992 T3987 aux could,detected
R811 T3993 T3987 auxpass be,detected
R812 T3994 T3987 prep at,detected
R813 T3995 T3994 pobj E15,at
R814 T3996 T3997 punct (,1E
R815 T3997 T3987 parataxis 1E,detected
R816 T3998 T3997 compound Figure,1E
R817 T3999 T3997 punct ),1E
R818 T4000 T3987 punct .,detected
R819 T4002 T4003 npadvmod TrkA,positive
R820 T4003 T4005 amod positive,fibers
R821 T4004 T4003 punct -,positive
R822 T4005 T4006 nsubj fibers,restricted
R823 T4007 T4006 aux were,restricted
R824 T4008 T4006 prep to,restricted
R825 T4009 T4006 cc and,restricted
R826 T4010 T4006 conj terminated,restricted
R827 T4011 T4010 prep in,terminated
R828 T4012 T4013 det the,cord
R829 T4013 T4010 dobj cord,terminated
R830 T4014 T4013 amod dorsolateral,cord
R831 T4015 T4013 amod spinal,cord
R832 T4016 T4006 punct ", ",restricted
R833 T4017 T4018 mark whereas,entered
R834 T4018 T4006 advcl entered,restricted
R835 T4019 T4020 npadvmod TrkC,positive
R836 T4020 T4022 amod positive,fibers
R837 T4021 T4020 punct -,positive
R838 T4022 T4018 nsubj fibers,entered
R839 T4023 T4024 det the,cord
R840 T4024 T4018 dobj cord,entered
R841 T4025 T4018 advmod dorsomedially,entered
R842 T4026 T4018 punct ", ",entered
R843 T4027 T4018 cc and,entered
R844 T4028 T4018 conj descended,entered
R845 T4029 T4028 prep into,descended
R846 T4030 T4031 det the,horns
R847 T4031 T4029 pobj horns,into
R848 T4032 T4031 amod ventral,horns
R849 T4033 T4031 prep in,horns
R850 T4034 T4035 nmod WT,embryos
R851 T4035 T4033 pobj embryos,in
R852 T4036 T4037 punct (,Ozaki
R853 T4037 T4034 meta Ozaki,WT
R854 T4038 T4037 cc and,Ozaki
R855 T4039 T4037 conj Snider,Ozaki
R856 T4040 T4039 nummod 1997,Snider
R857 T4041 T4039 punct ),Snider
R858 T4042 T4034 cc and,WT
R859 T4043 T4044 compound Bax,KO
R860 T4044 T4034 conj KO,WT
R861 T4045 T4006 punct .,restricted
R862 T4047 T4048 expl There,was
R863 T4049 T4050 det no,expression
R864 T4050 T4048 attr expression,was
R865 T4051 T4050 amod detectable,expression
R866 T4052 T4050 compound TrkC,expression
R867 T4053 T4048 prep in,was
R868 T4054 T4055 nmod NT,KO
R869 T4055 T4058 nmod KO,cord
R870 T4056 T4054 punct -,NT
R871 T4057 T4054 nummod 3,NT
R872 T4058 T4053 pobj cord,in
R873 T4059 T4058 amod spinal,cord
R874 T4060 T4048 punct ", ",was
R875 T4061 T4048 advcl indicating,was
R876 T4062 T4063 amod complete,absence
R877 T4063 T4061 dobj absence,indicating
R878 T4064 T4063 prep of,absence
R879 T4065 T4066 amod proprioceptive,fibers
R880 T4066 T4064 pobj fibers,of
R881 T4067 T4048 punct .,was
R882 T4069 T4070 prep In,entered
R883 T4071 T4072 amod double,KO
R884 T4072 T4073 nmod KO,cord
R885 T4073 T4069 pobj cord,In
R886 T4074 T4073 amod spinal,cord
R887 T4075 T4070 punct ", ",entered
R888 T4076 T4077 npadvmod TrkC,positive
R889 T4077 T4079 amod positive,fibers
R890 T4078 T4077 punct -,positive
R891 T4079 T4070 nsubj fibers,entered
R892 T4080 T4081 det the,cord
R893 T4081 T4070 dobj cord,entered
R894 T4082 T4081 amod dorsal,cord
R895 T4083 T4081 amod spinal,cord
R896 T4084 T4070 cc and,entered
R897 T4085 T4070 conj descended,entered
R898 T4086 T4085 advmod medially,descended
R899 T4087 T4085 prep in,descended
R900 T4088 T4089 det a,manner
R901 T4089 T4087 pobj manner,in
R902 T4090 T4089 amod similar,manner
R903 T4091 T4090 prep to,similar
R904 T4092 T4091 pobj that,to
R905 T4093 T4092 acl seen,that
R906 T4094 T4093 prep in,seen
R907 T4095 T4096 nmod WT,cases
R908 T4096 T4094 pobj cases,in
R909 T4097 T4095 cc or,WT
R910 T4098 T4099 compound Bax,KO
R911 T4099 T4095 conj KO,WT
R912 T4100 T4070 punct .,entered
R913 T4102 T4103 advmod However,was
R914 T4104 T4103 punct ", ",was
R915 T4105 T4103 nsubj it,was
R916 T4106 T4103 neg not,was
R917 T4107 T4103 acomp possible,was
R918 T4108 T4109 aux to,follow
R919 T4109 T4103 xcomp follow,was
R920 T4110 T4111 nmod TrkC,fibers
R921 T4111 T4109 dobj fibers,follow
R922 T4112 T4111 amod immunolabeled,fibers
R923 T4113 T4114 predet all,way
R924 T4114 T4116 npadvmod way,to
R925 T4115 T4114 det the,way
R926 T4116 T4109 prep to,follow
R927 T4117 T4118 poss their,zones
R928 T4118 T4116 pobj zones,to
R929 T4119 T4118 amod terminal,zones
R930 T4120 T4109 prep in,follow
R931 T4121 T4120 pobj any,in
R932 T4122 T4121 prep of,any
R933 T4123 T4124 det the,cases
R934 T4124 T4122 pobj cases,of
R935 T4125 T4103 punct .,was
R936 T4127 T4128 advmod Next,examined
R937 T4129 T4128 nsubj we,examined
R938 T4130 T4131 det the,projections
R939 T4131 T4128 dobj projections,examined
R940 T4132 T4131 amod central,projections
R941 T4133 T4131 prep of,projections
R942 T4134 T4135 compound DRG,axons
R943 T4135 T4133 pobj axons,of
R944 T4136 T4128 prep with,examined
R945 T4137 T4138 det the,tracer
R946 T4138 T4136 pobj tracer,with
R947 T4139 T4138 amod lipophilic,tracer
R948 T4140 T4138 appos DiI,tracer
R949 T4141 T4128 prep at,examined
R950 T4142 T4141 pobj P0,at
R951 T4143 T4128 punct .,examined
R952 T4145 T4146 prep In,entered
R953 T4147 T4148 nmod WT,pups
R954 T4148 T4145 pobj pups,In
R955 T4149 T4147 cc and,WT
R956 T4150 T4151 compound Bax,KO
R957 T4151 T4147 conj KO,WT
R958 T4152 T4146 punct ", ",entered
R959 T4153 T4154 amod proprioceptive,afferents
R960 T4154 T4146 nsubj afferents,entered
R961 T4155 T4156 det the,cord
R962 T4156 T4146 dobj cord,entered
R963 T4157 T4156 amod dorsal,cord
R964 T4158 T4156 amod spinal,cord
R965 T4159 T4146 cc and,entered
R966 T4160 T4146 conj followed,entered
R967 T4161 T4162 det a,course
R968 T4162 T4160 dobj course,followed
R969 T4163 T4162 amod medial,course
R970 T4164 T4162 prep towards,course
R971 T4165 T4166 det the,horn
R972 T4166 T4164 pobj horn,towards
R973 T4167 T4166 amod ventral,horn
R974 T4168 T4146 punct .,entered
R975 T4170 T4171 nsubj They,turned
R976 T4172 T4171 advmod then,turned
R977 T4173 T4171 advmod laterally,turned
R978 T4174 T4171 prep towards,turned
R979 T4175 T4176 compound motor,neurons
R980 T4176 T4174 pobj neurons,towards
R981 T4177 T4176 prep in,neurons
R982 T4178 T4179 det the,column
R983 T4179 T4177 pobj column,in
R984 T4180 T4179 amod lateral,column
R985 T4181 T4179 compound motor,column
R986 T4182 T4179 punct ", ",column
R987 T4183 T4184 advmod where,branched
R988 T4184 T4179 relcl branched,column
R989 T4185 T4184 nsubj they,branched
R990 T4186 T4184 cc and,branched
R991 T4187 T4184 conj terminated,branched
R992 T4188 T4189 punct (,2A
R993 T4189 T4171 parataxis 2A,turned
R994 T4190 T4189 compound Figure,2A
R995 T4191 T4189 punct ),2A
R996 T4192 T4171 punct .,turned
R997 T4194 T4195 compound DiI,labeling
R998 T4195 T4196 nsubjpass labeling,confined
R999 T4197 T4196 auxpass was,confined
R1000 T4198 T4196 prep to,confined
R1001 T4199 T4200 amod dorsal,cord
R1002 T4200 T4198 pobj cord,to
R1003 T4201 T4200 amod spinal,cord
R1004 T4202 T4200 prep in,cord
R1005 T4203 T4204 nmod NT,KOs
R1006 T4204 T4202 pobj KOs,in
R1007 T4205 T4203 punct -,NT
R1008 T4206 T4203 nummod 3,NT
R1009 T4207 T4208 punct (,2A
R1010 T4208 T4196 parataxis 2A,confined
R1011 T4209 T4208 compound Figure,2A
R1012 T4210 T4208 punct ),2A
R1013 T4211 T4196 punct ", ",confined
R1014 T4212 T4213 mark as,reported
R1015 T4213 T4196 advcl reported,confined
R1016 T4214 T4213 advmod earlier,reported
R1017 T4215 T4196 punct ", ",confined
R1018 T4216 T4196 advcl consistent,confined
R1019 T4217 T4216 prep with,consistent
R1020 T4218 T4219 det a,absence
R1021 T4219 T4217 pobj absence,with
R1022 T4220 T4219 amod complete,absence
R1023 T4221 T4219 prep of,absence
R1024 T4222 T4223 amod proprioceptive,innervation
R1025 T4223 T4221 pobj innervation,of
R1026 T4224 T4225 punct (,Ernfors
R1027 T4225 T4216 meta Ernfors,consistent
R1028 T4226 T4225 nmod et,Ernfors
R1029 T4227 T4225 nmod al.,Ernfors
R1030 T4228 T4225 nummod 1994,Ernfors
R1031 T4229 T4225 punct ;,Ernfors
R1032 T4230 T4225 nmod Tessarollo,Ernfors
R1033 T4231 T4225 nmod et,Ernfors
R1034 T4232 T4225 nmod al.,Ernfors
R1035 T4233 T4225 nummod 1994,Ernfors
R1036 T4234 T4225 punct ),Ernfors
R1037 T4235 T4196 punct .,confined
R1038 T4237 T4238 prep In,followed
R1039 T4239 T4240 amod double,KOs
R1040 T4240 T4237 pobj KOs,In
R1041 T4241 T4238 punct ", ",followed
R1042 T4242 T4243 amod proprioceptive,afferents
R1043 T4243 T4238 nsubj afferents,followed
R1044 T4244 T4238 advmod initially,followed
R1045 T4245 T4246 det a,trajectory
R1046 T4246 T4238 dobj trajectory,followed
R1047 T4247 T4246 amod similar,trajectory
R1048 T4248 T4247 prep to,similar
R1049 T4249 T4248 pobj that,to
R1050 T4250 T4249 prep of,that
R1051 T4251 T4252 compound WT,counterparts
R1052 T4252 T4250 pobj counterparts,of
R1053 T4253 T4238 punct ", ",followed
R1054 T4254 T4238 cc but,followed
R1055 T4255 T4256 nsubj most,failed
R1056 T4256 T4238 conj failed,followed
R1057 T4257 T4255 prep of,most
R1058 T4258 T4257 pobj them,of
R1059 T4259 T4260 aux to,project
R1060 T4260 T4256 xcomp project,failed
R1061 T4261 T4262 predet all,way
R1062 T4262 T4264 npadvmod way,to
R1063 T4263 T4262 det the,way
R1064 T4264 T4260 prep to,project
R1065 T4265 T4266 det the,cord
R1066 T4266 T4264 pobj cord,to
R1067 T4267 T4266 amod ventral,cord
R1068 T4268 T4264 cc and,to
R1069 T4269 T4264 conj into,to
R1070 T4270 T4271 det the,column
R1071 T4271 T4269 pobj column,into
R1072 T4272 T4271 amod lateral,column
R1073 T4273 T4271 compound motor,column
R1074 T4274 T4256 punct .,failed
R1075 T4276 T4277 advmod Instead,arborized
R1076 T4277 T4280 ccomp arborized,crossed
R1077 T4278 T4277 punct ", ",arborized
R1078 T4279 T4277 nsubj they,arborized
R1079 T4281 T4277 prep near,arborized
R1080 T4282 T4283 det the,midline
R1081 T4283 T4281 pobj midline,near
R1082 T4284 T4283 amod ventral,midline
R1083 T4285 T4280 punct ;,crossed
R1084 T4286 T4280 nsubj some,crossed
R1085 T4287 T4288 det the,midline
R1086 T4288 T4280 dobj midline,crossed
R1087 T4289 T4280 cc and,crossed
R1088 T4290 T4280 conj extended,crossed
R1089 T4291 T4290 prep into,extended
R1090 T4292 T4293 det the,cord
R1091 T4293 T4291 pobj cord,into
R1092 T4294 T4293 amod contralateral,cord
R1093 T4295 T4293 amod ventral,cord
R1094 T4296 T4297 punct (,2A
R1095 T4297 T4290 parataxis 2A,extended
R1096 T4298 T4297 compound Figure,2A
R1097 T4299 T4297 cc and,2A
R1098 T4300 T4297 conj 2C,2A
R1099 T4301 T4297 punct ),2A
R1100 T4302 T4280 punct .,crossed
R1101 T4304 T4305 prep In,repeated
R1102 T4306 T4304 pobj order,In
R1103 T4307 T4308 aux to,distinguish
R1104 T4308 T4306 acl distinguish,order
R1105 T4309 T4308 prep between,distinguish
R1106 T4310 T4311 det a,role
R1107 T4311 T4309 pobj role,between
R1108 T4312 T4311 prep for,role
R1109 T4313 T4312 pobj NT,for
R1110 T4314 T4313 punct -,NT
R1111 T4315 T4313 nummod 3,NT
R1112 T4316 T4311 prep in,role
R1113 T4317 T4316 pobj initiation,in
R1114 T4318 T4317 prep of,initiation
R1115 T4319 T4320 compound motor,neuron
R1116 T4320 T4321 compound neuron,innervation
R1117 T4321 T4318 pobj innervation,of
R1118 T4322 T4311 cc and,role
R1119 T4323 T4324 det a,role
R1120 T4324 T4311 conj role,role
R1121 T4325 T4324 prep for,role
R1122 T4326 T4325 pobj maintenance,for
R1123 T4327 T4305 punct ", ",repeated
R1124 T4328 T4305 nsubj we,repeated
R1125 T4329 T4330 det the,labeling
R1126 T4330 T4305 dobj labeling,repeated
R1127 T4331 T4330 compound DiI,labeling
R1128 T4332 T4305 prep at,repeated
R1129 T4333 T4332 pobj E17,at
R1130 T4334 T4305 punct .,repeated
R1131 T4336 T4337 compound Innervation,patterns
R1132 T4337 T4338 nsubj patterns,were
R1133 T4339 T4337 prep of,patterns
R1134 T4340 T4341 nmod E17,cords
R1135 T4341 T4339 pobj cords,of
R1136 T4342 T4341 amod spinal,cords
R1137 T4343 T4344 punct (,Figure
R1138 T4344 T4337 parataxis Figure,patterns
R1139 T4345 T4344 nummod 3,Figure
R1140 T4346 T4344 punct ),Figure
R1141 T4347 T4338 acomp similar,were
R1142 T4348 T4347 prep to,similar
R1143 T4349 T4348 pobj those,to
R1144 T4350 T4349 prep at,those
R1145 T4351 T4350 pobj P0,at
R1146 T4352 T4353 punct (,Figure
R1147 T4353 T4349 parataxis Figure,those
R1148 T4354 T4353 nummod 2,Figure
R1149 T4355 T4353 punct ),Figure
R1150 T4356 T4338 punct .,were
R1151 T4358 T4359 amod Dorsal,horns
R1152 T4359 T4360 nsubjpass horns,filled
R1153 T4361 T4359 prep of,horns
R1154 T4362 T4363 det all,genotypes
R1155 T4363 T4361 pobj genotypes,of
R1156 T4364 T4360 auxpass were,filled
R1157 T4365 T4360 agent with,filled
R1158 T4366 T4367 npadvmod DiI,labeled
R1159 T4367 T4369 amod labeled,fibers
R1160 T4368 T4367 punct -,labeled
R1161 T4369 T4365 pobj fibers,with
R1162 T4370 T4369 acl corresponding,fibers
R1163 T4371 T4370 prep to,corresponding
R1164 T4372 T4373 compound nerve,factor
R1165 T4373 T4375 npadvmod factor,dependent
R1166 T4374 T4373 compound growth,factor
R1167 T4375 T4377 amod dependent,axons
R1168 T4376 T4375 punct –,dependent
R1169 T4377 T4371 pobj axons,to
R1170 T4378 T4377 amod nociceptive,axons
R1171 T4379 T4360 punct .,filled
R1172 T4381 T4382 prep In,extended
R1173 T4383 T4384 nmod WT,embryos
R1174 T4384 T4381 pobj embryos,In
R1175 T4385 T4383 cc and,WT
R1176 T4386 T4387 compound Bax,KO
R1177 T4387 T4383 conj KO,WT
R1178 T4388 T4382 punct ", ",extended
R1179 T4389 T4390 amod proprioceptive,fibers
R1180 T4390 T4382 nsubj fibers,extended
R1181 T4391 T4382 prep towards,extended
R1182 T4392 T4393 amod ventral,horn
R1183 T4393 T4394 compound horn,neurons
R1184 T4394 T4391 pobj neurons,towards
R1185 T4395 T4394 compound motor,neurons
R1186 T4396 T4397 punct (,3A
R1187 T4397 T4394 parataxis 3A,neurons
R1188 T4398 T4397 compound Figure,3A
R1189 T4399 T4397 cc and,3A
R1190 T4400 T4397 conj 3B,3A
R1191 T4401 T4397 punct ),3A
R1192 T4402 T4382 punct ", ",extended
R1193 T4403 T4404 mark whereas,were
R1194 T4404 T4382 advcl were,extended
R1195 T4405 T4406 det the,horns
R1196 T4406 T4404 nsubj horns,were
R1197 T4407 T4406 amod ventral,horns
R1198 T4408 T4406 prep of,horns
R1199 T4409 T4410 det the,embryos
R1200 T4410 T4408 pobj embryos,of
R1201 T4411 T4412 nmod NT,KO
R1202 T4412 T4410 compound KO,embryos
R1203 T4413 T4411 punct -,NT
R1204 T4414 T4411 nummod 3,NT
R1205 T4415 T4404 acomp devoid,were
R1206 T4416 T4415 prep of,devoid
R1207 T4417 T4416 pobj innervation,of
R1208 T4418 T4419 punct (,3C
R1209 T4419 T4404 parataxis 3C,were
R1210 T4420 T4419 compound Figure,3C
R1211 T4421 T4419 punct ),3C
R1212 T4422 T4382 punct .,extended
R1213 T4424 T4425 prep In,entered
R1214 T4426 T4427 det the,KOs
R1216 T4428 T4427 nmod Bax,KOs
R1217 T4429 T4428 punct /,Bax
R1218 T4430 T4428 appos NT,Bax
R1219 T4431 T4430 punct -,NT
R1220 T4432 T4430 nummod 3,NT
R1221 T4433 T4427 amod double,KOs
R1222 T4434 T4425 punct ", ",entered
R1223 T4435 T4436 npadvmod DiI,labeled
R1224 T4436 T4438 amod labeled,fibers
R1225 T4437 T4436 punct -,labeled
R1226 T4438 T4425 nsubj fibers,entered
R1227 T4439 T4440 det the,cord
R1228 T4440 T4425 dobj cord,entered
R1229 T4441 T4440 amod ventral,cord
R1230 T4442 T4440 amod spinal,cord
R1231 T4443 T4425 punct ", ",entered
R1232 T4444 T4425 cc but,entered
R1233 T4445 T4425 conj extended,entered
R1234 T4446 T4445 prep towards,extended
R1235 T4447 T4448 det the,midline
R1236 T4448 T4446 pobj midline,towards
R1237 T4449 T4450 advmod instead,of
R1238 T4450 T4448 cc of,midline
R1239 T4451 T4452 det the,horn
R1240 T4452 T4448 conj horn,midline
R1241 T4453 T4452 amod ventral,horn
R1242 T4454 T4455 punct (,3D
R1243 T4455 T4445 parataxis 3D,extended
R1244 T4456 T4455 compound Figure,3D
R1245 T4457 T4455 punct ),3D
R1246 T4458 T4445 punct ", ",extended
R1247 T4459 T4445 prep in,extended
R1248 T4460 T4461 det a,pattern
R1249 T4461 T4459 pobj pattern,in
R1250 T4542 T4543 det the,absence
R1251 T4462 T4461 amod similar,pattern
R1252 T4543 T4541 pobj absence,in
R1253 T4463 T4462 prep to,similar
R1254 T4544 T4543 prep of,absence
R1255 T4545 T4544 pobj NT,of
R1256 T4546 T4545 punct -,NT
R1257 T4464 T4463 pobj that,to
R1258 T4547 T4545 nummod 3,NT
R1259 T4548 T4549 det a,requirement
R1260 T4465 T4464 acl observed,that
R1261 T4549 T4531 dobj requirement,suggests
R1262 T4550 T4549 prep for,requirement
R1263 T4551 T4550 pobj NT,for
R1264 T4466 T4465 prep at,observed
R1265 T4552 T4551 punct -,NT
R1266 T4553 T4551 nummod 3,NT
R1267 T4467 T4466 pobj P0,at
R1268 T4554 T4549 prep for,requirement
R1269 T4555 T4556 amod proper,axon
R1270 T4468 T4425 punct .,entered
R1271 T4556 T4554 pobj axon,for
R1272 T4557 T4556 amod targeting,axon
R1273 T4470 T4471 poss Our,data
R1274 T4558 T4549 prep in,requirement
R1275 T4559 T4558 pobj addition,in
R1276 T4560 T4559 prep to,addition
R1277 T4561 T4562 det a,role
R1278 T4471 T4472 nsubj data,point
R1279 T4562 T4560 pobj role,to
R1280 T4563 T4562 prep in,role
R1281 T4473 T4472 prep to,point
R1282 T4564 T4565 amod sensory,axon
R1283 T4565 T4566 compound axon,maintenance
R1284 T4566 T4563 pobj maintenance,in
R1285 T4474 T4475 det a,absence
R1286 T4567 T4531 punct .,suggests
R1287 T4475 T4473 pobj absence,to
R1288 T4476 T4475 amod complete,absence
R1289 T4477 T4475 prep of,absence
R1290 T4478 T4479 amod proprioceptive,innervation
R1291 T4479 T4477 pobj innervation,of
R1292 T4480 T4479 prep of,innervation
R1293 T4481 T4482 det the,horn
R1294 T4482 T4480 pobj horn,of
R1295 T4483 T4482 amod ventral,horn
R1296 T4484 T4482 prep of,horn
R1297 T4485 T4486 det the,cord
R1298 T4486 T4484 pobj cord,of
R1299 T4487 T4488 npadvmod Bax,null
R1300 T4488 T4486 amod null,cord
R1301 T4489 T4487 punct /,Bax
R1302 T4490 T4487 appos NT,Bax
R1303 T4491 T4490 punct -,NT
R1304 T4492 T4490 nummod 3,NT
R1305 T4493 T4486 amod spinal,cord
R1306 T4494 T4475 prep throughout,absence
R1307 T4495 T4496 det the,stages
R1308 T4496 T4494 pobj stages,throughout
R1309 T4497 T4496 amod developmental,stages
R1310 T4498 T4496 acl investigated,stages
R1311 T4499 T4472 punct .,point
R1312 T4501 T4502 mark As,reach
R1313 T4502 T4507 advcl reach,established
R1314 T4503 T4504 det the,axons
R1315 T4504 T4502 nsubj axons,reach
R1316 T4505 T4504 amod sensory,axons
R1317 T4506 T4502 neg never,reach
R1318 T4508 T4509 compound motor,neuron
R1319 T4509 T4510 compound neuron,dendrites
R1320 T4510 T4502 dobj dendrites,reach
R1321 T4511 T4510 prep in,dendrites
R1322 T4512 T4513 det the,horn
R1323 T4513 T4511 pobj horn,in
R1324 T4514 T4513 amod ventral,horn
R1325 T4515 T4516 punct (,S1
R1326 T4516 T4502 parataxis S1,reach
R1327 T4517 T4516 compound Figure,S1
R1328 T4518 T4516 punct ),S1
R1329 T4519 T4507 punct ", ",established
R1330 T4520 T4521 det the,circuit
R1331 T4521 T4507 nsubjpass circuit,established
R1332 T4522 T4523 compound stretch,reflex
R1333 T4523 T4521 compound reflex,circuit
R1334 T4524 T4521 compound arc,circuit
R1335 T4525 T4507 auxpass is,established
R1336 T4526 T4507 neg not,established
R1337 T4527 T4507 punct .,established
R1338 T4529 T4530 det The,failure
R1339 T4530 T4531 nsubj failure,suggests
R1340 T4532 T4533 aux to,initiate
R1341 T4533 T4530 acl initiate,failure
R1342 T4534 T4533 dobj contact,initiate
R1343 T4535 T4534 prep between,contact
R1344 T4536 T4537 amod sensory,axons
R1345 T4537 T4535 pobj axons,between
R1346 T4538 T4537 cc and,axons
R1347 T4539 T4540 compound motor,neurons
R1348 T4540 T4537 conj neurons,axons
R1349 T4541 T4533 prep in,initiate
R1352 T5932 T5933 nsubjpass NT,Required
R1353 T5934 T5932 punct -,NT
R1354 T5935 T5932 nummod 3,NT
R1355 T5936 T5933 auxpass Is,Required
R1356 T5937 T5933 prep for,Required
R1357 T5938 T5939 amod Proper,Innervation
R1358 T5939 T5937 pobj Innervation,for
R1359 T5940 T5939 amod Peripheral,Innervation
R1360 T5942 T5943 prep In,investigated
R1361 T5944 T5942 pobj order,In
R1362 T5945 T5946 aux to,study
R1363 T5946 T5944 acl study,order
R1364 T5947 T5948 amod peripheral,innervation
R1365 T5948 T5946 dobj innervation,study
R1366 T5949 T5946 prep in,study
R1367 T5950 T5951 amod double,KO
R1368 T5951 T5952 compound KO,animals
R1369 T5952 T5949 pobj animals,in
R1370 T5953 T5943 punct ", ",investigated
R1371 T5954 T5943 nsubj we,investigated
R1372 T5955 T5956 compound spindle,development
R1373 T5956 T5943 dobj development,investigated
R1374 T5957 T5956 prep in,development
R1375 T5958 T5959 det the,muscle
R1376 T5959 T5957 pobj muscle,in
R1377 T5960 T5959 compound gastrocnemius,muscle
R1378 T5961 T5943 punct .,investigated
R1379 T5963 T5964 compound Muscle,spindles
R1380 T5964 T5965 nsubjpass spindles,identified
R1381 T5966 T5965 aux could,identified
R1382 T5967 T5965 auxpass be,identified
R1383 T5968 T5965 advmod easily,identified
R1384 T5969 T5965 prep in,identified
R1385 T5970 T5971 nmod P0,animals
R1386 T5971 T5969 pobj animals,in
R1387 T5972 T5971 nmod WT,animals
R1388 T5973 T5972 cc and,WT
R1389 T5974 T5975 compound Bax,KO
R1390 T5975 T5972 conj KO,WT
R1391 T5976 T5965 prep by,identified
R1392 T5977 T5978 poss their,morphology
R1393 T5978 T5976 pobj morphology,by
R1394 T5979 T5978 amod characteristic,morphology
R1395 T5980 T5981 punct (,4A
R1396 T5981 T5965 parataxis 4A,identified
R1397 T5982 T5981 compound Figure,4A
R1398 T5983 T5981 cc and,4A
R1399 T5984 T5981 conj 4B,4A
R1400 T5985 T5981 punct ),4A
R1401 T5986 T5965 punct .,identified
R1402 T5988 T5989 amod Proprioceptive,fibers
R1403 T5989 T5990 nsubj fibers,formed
R1404 T5991 T5989 acl labeled,fibers
R1405 T5992 T5991 prep with,labeled
R1406 T5993 T5994 nmod neurofilament,M
R1407 T5994 T5996 nmod M,antibody
R1408 T5995 T5994 punct -,M
R1409 T5996 T5992 pobj antibody,with
R1410 T5997 T5994 punct (,M
R1411 T5998 T5999 compound NF,M
R1412 T5999 T5994 appos M,M
R1413 T6000 T5999 punct -,M
R1414 T6001 T5996 punct ),antibody
R1415 T6002 T6003 npadvmod ring,like
R1416 T6003 T6005 amod like,endings
R1417 T6004 T6003 punct -,like
R1418 T6005 T5990 dobj endings,formed
R1419 T6006 T6005 amod spiral,endings
R1420 T6007 T6005 acl wrapped,endings
R1421 T6008 T6007 prep around,wrapped
R1422 T6009 T6010 amod intrafusal,fibers
R1423 T6010 T6008 pobj fibers,around
R1424 T6011 T6010 compound bag,fibers
R1425 T6012 T6010 acl labeled,fibers
R1426 T6013 T6012 prep with,labeled
R1427 T6014 T6015 compound S46,antibody
R1428 T6015 T6013 pobj antibody,with
R1429 T6016 T6015 punct ", ",antibody
R1430 T6017 T6015 amod specific,antibody
R1431 T6018 T6017 prep for,specific
R1432 T6019 T6020 amod slow,developmental
R1433 T6020 T6021 amod developmental,protein
R1434 T6021 T6018 pobj protein,for
R1435 T6022 T6021 nmod myosin,protein
R1436 T6023 T6024 amod heavy,chain
R1437 T6024 T6021 compound chain,protein
R1438 T6025 T6026 punct (,Miller
R1439 T6026 T5990 meta Miller,formed
R1440 T6027 T6026 nmod et,Miller
R1441 T6028 T6026 nmod al.,Miller
R1442 T6029 T6026 nummod 1985,Miller
R1443 T6030 T6026 punct ),Miller
R1444 T6031 T5990 punct .,formed
R1445 T6033 T6034 mark As,reported
R1446 T6034 T6035 advcl reported,were
R1447 T6036 T6034 advmod earlier,reported
R1448 T6037 T6035 punct ", ",were
R1449 T6038 T6035 expl there,were
R1450 T6039 T6040 det no,spindles
R1451 T6040 T6035 attr spindles,were
R1452 T6041 T6040 compound muscle,spindles
R1453 T6042 T6035 prep in,were
R1454 T6043 T6044 nmod NT,KO
R1455 T6044 T6047 compound KO,animals
R1456 T6045 T6043 punct -,NT
R1457 T6046 T6043 nummod 3,NT
R1458 T6047 T6042 pobj animals,in
R1459 T6048 T6049 punct (,Ernfors
R1460 T6049 T6035 meta Ernfors,were
R1461 T6050 T6049 nmod et,Ernfors
R1462 T6051 T6049 nmod al.,Ernfors
R1463 T6052 T6049 nummod 1994,Ernfors
R1464 T6053 T6049 punct ),Ernfors
R1465 T6054 T6035 punct .,were
R1466 T6056 T6057 prep On,had
R1467 T6058 T6059 det the,hand
R1468 T6059 T6056 pobj hand,On
R1469 T6060 T6059 amod other,hand
R1470 T6061 T6057 punct ", ",had
R1471 T6062 T6063 compound Bax,KO
R1472 T6063 T6064 compound KO,animals
R1473 T6064 T6057 nsubj animals,had
R1474 T6065 T6066 amod more,spindles
R1475 T6066 T6057 dobj spindles,had
R1476 T6067 T6068 mark than,WT
R1477 T6068 T6066 advcl WT,spindles
R1478 T6069 T6057 punct ", ",had
R1479 T6070 T6057 cc and,had
R1480 T6071 T6072 nsubj spindles,were
R1481 T6072 T6057 conj were,had
R1482 T6073 T6072 prep in,were
R1483 T6074 T6073 pobj clusters,in
R1484 T6075 T6072 advcl similar,were
R1485 T6076 T6075 prep to,similar
R1486 T6077 T6076 pobj animals,to
R1487 T6078 T6077 acl over-expressing,animals
R1488 T6079 T6078 dobj NT,over-expressing
R1489 T6080 T6079 punct -,NT
R1490 T6081 T6079 nummod 3,NT
R1491 T6082 T6078 prep in,over-expressing
R1492 T6083 T6084 det the,muscle
R1493 T6084 T6082 pobj muscle,in
R1494 T6085 T6086 punct (,Wright
R1495 T6086 T6072 meta Wright,were
R1496 T6087 T6086 nmod et,Wright
R1497 T6088 T6086 nmod al.,Wright
R1498 T6089 T6086 nummod 1997,Wright
R1499 T6090 T6086 punct ),Wright
R1500 T6091 T6072 punct .,were
R1501 T6093 T6094 mark Although,rescued
R1502 T6094 T6102 advcl rescued,detected
R1503 T6095 T6096 npadvmod NT,dependent
R1504 T6096 T6100 amod dependent,cells
R1505 T6097 T6095 punct -,NT
R1506 T6098 T6095 nummod 3,NT
R1507 T6099 T6096 punct -,dependent
R1508 T6100 T6094 nsubjpass cells,rescued
R1509 T6101 T6094 auxpass were,rescued
R1510 T6103 T6102 punct ", ",detected
R1511 T6104 T6105 det no,spindles
R1512 T6105 T6102 nsubjpass spindles,detected
R1513 T6106 T6105 compound muscle,spindles
R1514 T6107 T6102 auxpass were,detected
R1515 T6108 T6102 prep in,detected
R1516 T6109 T6110 det the,limbs
R1517 T6110 T6108 pobj limbs,in
R1518 T6111 T6110 prep of,limbs
R1519 T6112 T6113 amod double,KOs
R1520 T6113 T6111 pobj KOs,of
R1521 T6114 T6115 punct (,4A
R1522 T6115 T6102 parataxis 4A,detected
R1523 T6116 T6115 compound Figure,4A
R1524 T6117 T6115 cc and,4A
R1525 T6118 T6115 conj 4B,4A
R1526 T6119 T6115 punct ),4A
R1527 T6120 T6102 punct .,detected
R1528 T6122 T6123 compound Muscle,spindles
R1529 T6123 T6124 nsubjpass spindles,observed
R1530 T6125 T6124 aux could,observed
R1531 T6126 T6124 auxpass be,observed
R1532 T6127 T6124 prep with,observed
R1533 T6128 T6129 compound TrkC,antibody
R1534 T6129 T6127 pobj antibody,with
R1535 T6130 T6124 prep in,observed
R1536 T6131 T6132 nmod WT,animals
R1537 T6132 T6130 pobj animals,in
R1538 T6133 T6131 cc and,WT
R1539 T6134 T6135 compound Bax,KO
R1540 T6135 T6131 conj KO,WT
R1541 T6136 T6130 punct ", ",in
R1542 T6137 T6130 cc but,in
R1543 T6138 T6137 neg not,but
R1544 T6139 T6130 conj in,in
R1545 T6140 T6141 nmod NT,KOs
R1546 T6141 T6139 pobj KOs,in
R1547 T6142 T6140 punct -,NT
R1548 T6143 T6140 nummod 3,NT
R1549 T6144 T6140 cc or,NT
R1550 T6145 T6140 conj double,NT
R1551 T6146 T6147 punct (,4E
R1552 T6147 T6124 parataxis 4E,observed
R1553 T6148 T6147 compound Figure,4E
R1554 T6149 T6147 punct ),4E
R1555 T6150 T6124 punct .,observed
R1556 T6152 T6153 prep In,detected
R1557 T6153 T6171 ccomp detected,were
R1558 T6154 T6155 preconj both,NT
R1559 T6155 T6156 nmod NT,KO
R1560 T6156 T6161 compound KO,animals
R1561 T6157 T6155 punct -,NT
R1562 T6158 T6155 nummod 3,NT
R1563 T6159 T6155 cc and,NT
R1564 T6160 T6155 conj double,NT
R1565 T6161 T6152 pobj animals,In
R1566 T6162 T6153 punct ", ",detected
R1567 T6163 T6164 compound NF,M
R1568 T6164 T6166 npadvmod M,labeled
R1569 T6165 T6164 punct -,M
R1570 T6166 T6168 amod labeled,fibers
R1571 T6167 T6166 punct -,labeled
R1572 T6168 T6153 nsubjpass fibers,detected
R1573 T6169 T6153 aux could,detected
R1574 T6170 T6153 auxpass be,detected
R1575 T6172 T6153 prep in,detected
R1576 T6173 T6172 pobj muscles,in
R1577 T6174 T6171 punct ", ",were
R1578 T6175 T6171 advmod thus,were
R1579 T6176 T6177 det the,muscles
R1580 T6177 T6171 nsubj muscles,were
R1581 T6178 T6177 prep of,muscles
R1582 T6179 T6180 det these,animals
R1583 T6180 T6178 pobj animals,of
R1584 T6181 T6171 neg not,were
R1585 T6182 T6183 advmod completely,devoid
R1586 T6183 T6171 acomp devoid,were
R1587 T6184 T6183 prep of,devoid
R1588 T6185 T6186 compound nerve,fibers
R1589 T6186 T6184 pobj fibers,of
R1590 T6187 T6171 punct .,were
R1591 T6189 T6190 mark Since,were
R1592 T6190 T6192 advcl were,think
R1593 T6191 T6190 expl there,were
R1594 T6193 T6194 det no,fibers
R1595 T6194 T6190 attr fibers,were
R1596 T6195 T6194 nmod TrkC,fibers
R1597 T6196 T6195 punct -,TrkC
R1598 T6197 T6195 amod positive,TrkC
R1599 T6198 T6190 prep in,were
R1600 T6199 T6200 det these,muscles
R1601 T6200 T6198 pobj muscles,in
R1602 T6201 T6192 punct ", ",think
R1603 T6202 T6192 nsubj we,think
R1604 T6203 T6204 mark that,correspond
R1605 T6204 T6192 ccomp correspond,think
R1606 T6205 T6206 det these,fibers
R1607 T6206 T6204 nsubj fibers,correspond
R1608 T6207 T6208 compound NF,M
R1609 T6208 T6210 npadvmod M,labeled
R1610 T6209 T6208 punct -,M
R1611 T6210 T6206 amod labeled,fibers
R1612 T6211 T6210 punct -,labeled
R1613 T6212 T6204 prep to,correspond
R1614 T6213 T6214 compound motor,axons
R1615 T6214 T6212 pobj axons,to
R1616 T6215 T6192 punct .,think
R1617 T6217 T6218 nsubj Absence,be
R1618 T6219 T6217 prep of,Absence
R1619 T6220 T6221 compound muscle,spindles
R1620 T6221 T6219 pobj spindles,of
R1621 T6222 T6218 aux might,be
R1622 T6223 T6218 prep due,be
R1623 T6224 T6223 pcomp to,due
R1624 T6225 T6226 det a,failure
R1625 T6226 T6223 pobj failure,due
R1626 T6227 T6226 prep in,failure
R1627 T6228 T6227 pobj initiation,in
R1628 T6229 T6228 prep of,initiation
R1629 T6230 T6229 pobj differentiation,of
R1630 T6231 T6228 prep by,initiation
R1631 T6232 T6233 amod proprioceptive,axons
R1632 T6233 T6231 pobj axons,by
R1633 T6234 T6226 punct ", ",failure
R1634 T6235 T6226 cc or,failure
R1635 T6236 T6237 det a,failure
R1636 T6237 T6226 conj failure,failure
R1637 T6238 T6237 prep of,failure
R1638 T6239 T6238 pobj maturation,of
R1639 T6240 T6239 cc and,maturation
R1640 T6241 T6239 conj maintenance,maturation
R1641 T6242 T6239 prep in,maturation
R1642 T6243 T6244 det the,absence
R1643 T6244 T6242 pobj absence,in
R1644 T6245 T6244 prep of,absence
R1645 T6246 T6245 pobj NT,of
R1646 T6247 T6246 punct -,NT
R1647 T6248 T6246 nummod 3,NT
R1648 T6249 T6218 punct .,be
R1649 T6251 T6252 aux To,distinguish
R1650 T6252 T6253 advcl distinguish,investigated
R1651 T6254 T6252 prep between,distinguish
R1652 T6255 T6256 det these,possibilities
R1653 T6256 T6254 pobj possibilities,between
R1654 T6257 T6256 nummod two,possibilities
R1655 T6258 T6253 punct ", ",investigated
R1656 T6259 T6253 nsubj we,investigated
R1657 T6260 T6261 compound muscle,spindle
R1658 T6261 T6262 compound spindle,development
R1659 T6262 T6253 dobj development,investigated
R1660 T6263 T6253 prep at,investigated
R1661 T6264 T6263 pobj E15,at
R1662 T6265 T6264 cc and,E15
R1663 T6266 T6264 conj E17,E15
R1664 T6267 T6253 prep with,investigated
R1665 T6268 T6269 nmod S46,immunostaining
R1666 T6269 T6267 pobj immunostaining,with
R1667 T6270 T6268 punct /,S46
R1668 T6271 T6272 compound NF,M
R1669 T6272 T6268 appos M,S46
R1670 T6273 T6272 punct -,M
R1671 T6274 T6275 advmod as,as
R1672 T6275 T6269 cc as,immunostaining
R1673 T6276 T6275 advmod well,as
R1674 T6277 T6278 compound DiI,labeling
R1675 T6278 T6269 conj labeling,immunostaining
R1676 T6279 T6253 punct .,investigated
R1677 T6281 T6282 det No,structures
R1678 T6282 T6283 nsubjpass structures,detected
R1679 T6284 T6282 prep with,structures
R1680 T6285 T6286 det the,shape
R1681 T6286 T6284 pobj shape,with
R1682 T6287 T6286 amod characteristic,shape
R1683 T6288 T6289 compound muscle,spindle
R1684 T6289 T6286 compound spindle,shape
R1685 T6290 T6283 aux could,detected
R1686 T6291 T6283 auxpass be,detected
R1687 T6292 T6283 prep in,detected
R1688 T6293 T6292 pobj any,in
R1689 T6294 T6293 prep of,any
R1690 T6295 T6296 det the,genotypes
R1691 T6296 T6294 pobj genotypes,of
R1692 T6297 T6283 prep at,detected
R1693 T6298 T6297 pobj E15,at
R1694 T6299 T6300 punct (,S2
R1695 T6300 T6283 parataxis S2,detected
R1696 T6301 T6300 compound Figure,S2
R1697 T6302 T6300 punct ),S2
R1698 T6303 T6283 punct .,detected
R1699 T6305 T6306 advmod However,identified
R1700 T6307 T6306 punct ", ",identified
R1701 T6308 T6309 amod numerous,spindles
R1702 T6309 T6306 nsubjpass spindles,identified
R1703 T6310 T6309 amod developing,spindles
R1704 T6311 T6306 aux could,identified
R1705 T6312 T6306 auxpass be,identified
R1706 T6313 T6306 prep at,identified
R1707 T6314 T6313 pobj E17,at
R1708 T6315 T6306 prep in,identified
R1709 T6316 T6315 pobj WT,in
R1710 T6317 T6316 cc and,WT
R1711 T6318 T6319 compound Bax,KOs
R1712 T6319 T6316 conj KOs,WT
R1713 T6320 T6315 punct ", ",in
R1714 T6321 T6315 cc but,in
R1715 T6322 T6321 neg not,but
R1716 T6323 T6315 conj in,in
R1717 T6324 T6325 nmod NT,KO
R1718 T6325 T6328 compound KO,embryos
R1719 T6326 T6324 punct -,NT
R1720 T6327 T6324 nummod 3,NT
R1721 T6328 T6323 pobj embryos,in
R1722 T6329 T6330 punct (,4C
R1723 T6330 T6306 parataxis 4C,identified
R1724 T6331 T6330 compound Figure,4C
R1725 T6332 T6330 punct ),4C
R1726 T6333 T6306 punct .,identified
R1727 T6335 T6336 npadvmod Bax,null
R1728 T6336 T6342 amod null,muscles
R1729 T6337 T6335 punct /,Bax
R1730 T6338 T6335 appos NT,Bax
R1731 T6339 T6338 punct -,NT
R1732 T6340 T6338 nummod 3,NT
R1733 T6341 T6336 amod double,null
R1734 T6342 T6343 nsubj muscles,were
R1735 T6344 T6343 acomp devoid,were
R1736 T6345 T6344 prep of,devoid
R1737 T6346 T6345 pobj spindles,of
R1738 T6347 T6348 punct (,4C
R1739 T6348 T6344 parataxis 4C,devoid
R1740 T6349 T6348 compound Figure,4C
R1741 T6350 T6348 punct ),4C
R1742 T6351 T6343 punct ", ",were
R1743 T6352 T6343 prep except,were
R1744 T6353 T6352 prep for,except
R1745 T6354 T6355 nummod one,structure
R1746 T6355 T6353 pobj structure,for
R1747 T6356 T6357 npadvmod spindle,like
R1748 T6357 T6355 amod like,structure
R1749 T6358 T6357 punct -,like
R1750 T6359 T6355 acl observed,structure
R1751 T6360 T6359 prep in,observed
R1752 T6361 T6362 nummod one,leg
R1753 T6362 T6360 pobj leg,in
R1754 T6363 T6362 prep of,leg
R1755 T6364 T6365 det an,embryo
R1756 T6365 T6363 pobj embryo,of
R1757 T6366 T6367 punct (,denoted
R1758 T6367 T6343 parataxis denoted,were
R1759 T6368 T6369 compound Figure,4C
R1760 T6369 T6367 dep 4C,denoted
R1761 T6370 T6367 punct ", ",denoted
R1762 T6371 T6367 dep inset,denoted
R1763 T6372 T6367 punct ", ",denoted
R1764 T6373 T6367 prep by,denoted
R1765 T6374 T6375 det the,asterisk
R1766 T6375 T6373 pobj asterisk,by
R1767 T6376 T6367 punct ),denoted
R1768 T6377 T6343 punct .,were
R1769 T6379 T6380 compound DiI,labeling
R1770 T6380 T6381 nsubj labeling,yielded
R1771 T6382 T6380 prep through,labeling
R1772 T6383 T6384 det the,DRGs
R1773 T6384 T6382 pobj DRGs,through
R1774 T6385 T6380 prep at,labeling
R1775 T6386 T6385 pobj E17,at
R1776 T6387 T6388 amod similar,results
R1777 T6388 T6381 dobj results,yielded
R1778 T6389 T6381 punct ", ",yielded
R1779 T6390 T6391 mark with,identified
R1780 T6391 T6381 advcl identified,yielded
R1781 T6392 T6393 compound muscle,spindles
R1782 T6393 T6391 nsubj spindles,identified
R1783 T6394 T6391 prep in,identified
R1784 T6395 T6396 amod parallel,sections
R1785 T6396 T6394 pobj sections,in
R1786 T6397 T6396 prep in,sections
R1787 T6398 T6399 nmod WT,muscles
R1788 T6399 T6397 pobj muscles,in
R1789 T6400 T6398 cc and,WT
R1790 T6401 T6402 npadvmod Bax,null
R1791 T6402 T6398 conj null,WT
R1792 T6403 T6404 punct (,4D
R1793 T6404 T6396 parataxis 4D,sections
R1794 T6405 T6404 compound Figure,4D
R1795 T6406 T6404 punct ),4D
R1796 T6407 T6394 punct ", ",in
R1797 T6408 T6394 cc but,in
R1798 T6409 T6408 neg not,but
R1799 T6410 T6394 conj in,in
R1800 T6411 T6412 nmod NT,KO
R1801 T6412 T6417 compound KO,animals
R1802 T6413 T6411 punct -,NT
R1803 T6414 T6411 nummod 3,NT
R1804 T6415 T6411 cc or,NT
R1805 T6416 T6411 conj double,NT
R1806 T6417 T6410 pobj animals,in
R1807 T6418 T6381 punct .,yielded
R1808 T6420 T6421 mark Although,detected
R1809 T6421 T6428 advcl detected,formed
R1810 T6422 T6423 npadvmod DiI,labeled
R1811 T6423 T6425 amod labeled,fibers
R1812 T6424 T6423 punct -,labeled
R1813 T6425 T6421 nsubjpass fibers,detected
R1814 T6426 T6421 aux could,detected
R1815 T6427 T6421 auxpass be,detected
R1816 T6429 T6421 prep in,detected
R1817 T6430 T6431 amod double,null
R1818 T6431 T6432 amod null,muscles
R1819 T6432 T6429 pobj muscles,in
R1820 T6433 T6428 punct ", ",formed
R1821 T6434 T6428 nsubj they,formed
R1822 T6435 T6428 neg never,formed
R1823 T6436 T6437 npadvmod ring,like
R1824 T6437 T6439 amod like,structures
R1825 T6438 T6437 punct -,like
R1826 T6439 T6428 dobj structures,formed
R1827 T6440 T6439 amod characteristic,structures
R1828 T6441 T6440 prep of,characteristic
R1829 T6442 T6443 compound muscle,spindles
R1830 T6443 T6441 pobj spindles,of
R1831 T6444 T6428 punct .,formed
R1832 T6446 T6447 nsubj We,examined
R1833 T6448 T6447 advmod also,examined
R1834 T6449 T6450 compound TrkA,TrkC
R1835 T6450 T6452 compound TrkC,expression
R1836 T6451 T6450 punct /,TrkC
R1837 T6452 T6447 dobj expression,examined
R1838 T6453 T6447 prep at,examined
R1839 T6454 T6453 pobj P0,at
R1840 T6455 T6447 prep in,examined
R1841 T6456 T6457 det the,nerve
R1842 T6457 T6455 pobj nerve,in
R1843 T6458 T6457 amod tibial,nerve
R1844 T6459 T6457 punct ", ",nerve
R1845 T6460 T6461 dep which,carries
R1846 T6461 T6457 relcl carries,nerve
R1847 T6462 T6463 amod sensory,fibers
R1848 T6463 T6461 dobj fibers,carries
R1849 T6464 T6461 prep to,carries
R1850 T6465 T6466 det the,muscle
R1851 T6466 T6464 pobj muscle,to
R1852 T6467 T6466 compound gastrocnemius,muscle
R1853 T6468 T6469 advmod as,as
R1854 T6469 T6466 cc as,muscle
R1855 T6470 T6469 advmod well,as
R1856 T6471 T6472 det the,skin
R1857 T6472 T6466 conj skin,muscle
R1858 T6473 T6472 prep of,skin
R1859 T6474 T6475 det the,leg
R1860 T6475 T6473 pobj leg,of
R1861 T6476 T6475 amod lower,leg
R1862 T6477 T6447 punct .,examined
R1863 T6479 T6480 prep In,seen
R1864 T6480 T6492 ccomp seen,are
R1865 T6481 T6482 nmod NT,KOs
R1866 T6482 T6479 pobj KOs,In
R1867 T6483 T6481 punct -,NT
R1868 T6484 T6481 nummod 3,NT
R1869 T6485 T6480 punct ", ",seen
R1870 T6486 T6487 npadvmod TrkA,positive
R1871 T6487 T6489 amod positive,axons
R1872 T6488 T6487 punct -,positive
R1873 T6489 T6480 nsubjpass axons,seen
R1874 T6490 T6480 aux could,seen
R1875 T6491 T6480 auxpass be,seen
R1876 T6493 T6480 prep in,seen
R1877 T6494 T6495 det the,nerve
R1878 T6495 T6493 pobj nerve,in
R1879 T6496 T6495 amod tibial,nerve
R1880 T6497 T6480 cc but,seen
R1881 T6498 T6499 expl there,were
R1882 T6499 T6480 conj were,seen
R1883 T6500 T6501 det no,axons
R1884 T6501 T6499 attr axons,were
R1885 T6502 T6503 npadvmod TrkC,positive
R1886 T6503 T6501 amod positive,axons
R1887 T6504 T6503 punct -,positive
R1888 T6505 T6492 punct ;,are
R1889 T6506 T6492 prep in,are
R1890 T6507 T6506 pobj contrast,in
R1891 T6508 T6492 punct ", ",are
R1892 T6509 T6510 npadvmod TrkA,labeled
R1893 T6510 T6515 amod labeled,axons
R1894 T6511 T6509 punct -,TrkA
R1895 T6512 T6509 cc and,TrkA
R1896 T6513 T6509 conj TrkC,TrkA
R1897 T6514 T6510 punct -,labeled
R1898 T6515 T6492 nsubj axons,are
R1899 T6516 T6492 advmod both,are
R1900 T6517 T6492 acomp present,are
R1901 T6518 T6492 prep in,are
R1902 T6519 T6520 nmod WT,animals
R1903 T6520 T6518 pobj animals,in
R1904 T6521 T6519 punct ", ",WT
R1905 T6522 T6523 compound Bax,KO
R1906 T6523 T6519 conj KO,WT
R1907 T6524 T6523 punct ", ",KO
R1908 T6525 T6523 cc and,KO
R1909 T6526 T6527 amod double,KO
R1910 T6527 T6523 conj KO,KO
R1911 T6528 T6529 punct (,4F
R1912 T6529 T6492 parataxis 4F,are
R1913 T6530 T6529 compound Figure,4F
R1914 T6531 T6529 punct ),4F
R1915 T6532 T6492 punct .,are
R1916 T6534 T6535 det These,results
R1917 T6535 T6536 nsubj results,suggest
R1918 T6537 T6538 mark that,fail
R1919 T6538 T6536 ccomp fail,suggest
R1920 T6539 T6540 mark although,follow
R1921 T6540 T6538 advcl follow,fail
R1922 T6541 T6542 amod proprioceptive,axons
R1923 T6542 T6540 nsubj axons,follow
R1924 T6543 T6544 amod proper,trajectories
R1925 T6544 T6540 dobj trajectories,follow
R1926 T6545 T6540 prep in,follow
R1927 T6546 T6547 amod distal,nerves
R1928 T6547 T6545 pobj nerves,in
R1929 T6548 T6547 amod peripheral,nerves
R1930 T6549 T6538 punct ", ",fail
R1931 T6550 T6538 nsubj they,fail
R1932 T6551 T6552 aux to,innervate
R1933 T6552 T6538 xcomp innervate,fail
R1934 T6553 T6554 poss their,muscles
R1935 T6554 T6552 dobj muscles,innervate
R1936 T6555 T6554 compound target,muscles
R1937 T6556 T6552 prep in,innervate
R1938 T6557 T6558 det the,absence
R1939 T6558 T6556 pobj absence,in
R1940 T6559 T6558 prep of,absence
R1941 T6560 T6559 pobj NT,of
R1942 T6561 T6560 punct -,NT
R1943 T6562 T6560 nummod 3,NT
R1944 T6563 T6536 punct .,suggest
R1945 T7869 T7870 nsubj NT,Is
R1946 T7871 T7869 punct -,NT
R1947 T7872 T7869 nummod 3,NT
R1948 T7873 T7874 det a,Chemoattractant
R1949 T7874 T7870 attr Chemoattractant,Is
R1950 T7875 T7874 prep for,Chemoattractant
R1951 T7876 T7877 compound DRG,Axons
R1952 T7877 T7875 pobj Axons,for
R1953 T7878 T7879 advmod In,Vitro
R1954 T7879 T7870 advmod Vitro,Is
R1955 T7881 T7882 aux To,test
R1956 T7882 T7883 advcl test,performed
R1957 T7884 T7885 det the,hypothesis
R1958 T7885 T7882 dobj hypothesis,test
R1959 T7886 T7887 mark that,acts
R1960 T7887 T7885 acl acts,hypothesis
R1961 T7888 T7887 nsubj NT,acts
R1962 T7889 T7888 punct -,NT
R1963 T7890 T7888 nummod 3,NT
R1964 T7891 T7887 prep as,acts
R1965 T7892 T7893 det a,chemoattractant
R1966 T7893 T7891 pobj chemoattractant,as
R1967 T7894 T7893 prep for,chemoattractant
R1968 T7895 T7896 amod sensory,axons
R1969 T7896 T7894 pobj axons,for
R1970 T7897 T7883 punct ", ",performed
R1971 T7898 T7883 nsubj we,performed
R1972 T7899 T7900 det a,series
R1973 T7900 T7883 dobj series,performed
R1974 T7901 T7900 prep of,series
R1975 T7902 T7903 advmod in,vitro
R1976 T7903 T7904 amod vitro,assays
R1977 T7904 T7901 pobj assays,of
R1978 T7905 T7883 punct .,performed
R1979 T7907 T7908 amod Proprioceptive,axons
R1980 T7908 T7909 nsubj axons,enter
R1981 T7910 T7908 prep in,axons
R1982 T7911 T7910 pobj mice,in
R1983 T7912 T7913 det the,matter
R1984 T7913 T7909 dobj matter,enter
R1985 T7914 T7913 amod gray,matter
R1986 T7915 T7913 prep in,matter
R1987 T7916 T7917 det the,cord
R1988 T7917 T7915 pobj cord,in
R1989 T7918 T7917 amod spinal,cord
R1990 T7919 T7909 cc and,enter
R1991 T7920 T7909 conj advance,enter
R1992 T7921 T7920 advmod ventrally,advance
R1993 T7922 T7920 advcl parallel,advance
R1994 T7923 T7922 prep to,parallel
R1995 T7924 T7925 det the,midline
R1996 T7925 T7923 pobj midline,to
R1997 T7926 T7920 prep by,advance
R1998 T7927 T7926 pobj E13,by
R1999 T7928 T7920 cc and,advance
R2000 T7929 T7920 conj reach,advance
R2001 T7930 T7931 det the,neurons
R2002 T7931 T7929 dobj neurons,reach
R2003 T7932 T7931 compound motor,neurons
R2004 T7933 T7929 prep by,reach
R2005 T7934 T7933 pobj E15,by
R2006 T7935 T7936 punct (,Ozaki
R2007 T7936 T7929 meta Ozaki,reach
R2008 T7937 T7936 cc and,Ozaki
R2009 T7938 T7936 conj Snider,Ozaki
R2010 T7939 T7938 nummod 1994,Snider
R2011 T7940 T7938 punct ),Snider
R2012 T7941 T7909 punct .,enter
R2013 T7943 T7944 nsubj We,co-cultured
R2014 T7945 T7946 npadvmod collagen,embedded
R2015 T7946 T7948 amod embedded,explants
R2016 T7947 T7946 punct -,embedded
R2017 T7948 T7944 dobj explants,co-cultured
R2018 T7949 T7948 compound E13,explants
R2019 T7950 T7948 compound WT,explants
R2020 T7951 T7948 compound DRG,explants
R2021 T7952 T7944 prep with,co-cultured
R2022 T7953 T7954 npadvmod NT,soaked
R2023 T7954 T7958 amod soaked,beads
R2024 T7955 T7953 punct -,NT
R2025 T7956 T7953 nummod 3,NT
R2026 T7957 T7954 punct -,soaked
R2027 T7958 T7952 pobj beads,with
R2028 T7959 T7958 compound sepharose,beads
R2029 T7960 T7961 punct (,26
R2030 T7961 T7944 parataxis 26,co-cultured
R2031 T7962 T7961 nsubj n,26
R2032 T7963 T7961 punct =,26
R2033 T7964 T7961 punct ),26
R2034 T7965 T7944 punct .,co-cultured
R2035 T7967 T7968 compound Control,cultures
R2036 T7968 T7969 nsubjpass cultures,set
R2037 T7970 T7969 auxpass were,set
R2038 T7971 T7969 prt up,set
R2039 T7972 T7969 advcl using,set
R2040 T7973 T7974 amod bovine,albumin
R2041 T7974 T7976 npadvmod albumin,soaked
R2042 T7975 T7974 compound serum,albumin
R2043 T7976 T7989 amod soaked,beads
R2044 T7977 T7974 punct (,albumin
R2045 T7978 T7974 appos BSA,albumin
R2046 T7979 T7974 punct ),albumin
R2047 T7980 T7974 punct –,albumin
R2048 T7981 T7974 cc or,albumin
R2049 T7982 T7983 compound phosphate,saline
R2050 T7983 T7974 conj saline,albumin
R2051 T7984 T7983 compound buffer,saline
R2052 T7985 T7983 punct (,saline
R2053 T7986 T7983 appos PBS,saline
R2054 T7987 T7976 punct ),soaked
R2055 T7988 T7976 punct –,soaked
R2056 T7989 T7972 dobj beads,using
R2057 T7990 T7991 punct (,12
R2058 T7991 T7972 parataxis 12,using
R2059 T7992 T7991 nsubj n,12
R2060 T7993 T7991 punct =,12
R2061 T7994 T7991 punct ),12
R2062 T7995 T7969 punct .,set
R2063 T7997 T7998 compound DRG,axons
R2064 T7998 T7999 nsubj axons,began
R2065 T8000 T7999 xcomp extending,began
R2066 T8001 T8000 prep towards,extending
R2067 T8002 T8003 det the,source
R2068 T8003 T8001 pobj source,towards
R2069 T8004 T8003 amod localized,source
R2070 T8005 T8003 nmod NT,source
R2071 T8006 T8005 punct -,NT
R2072 T8007 T8005 nummod 3,NT
R2073 T8008 T8000 prep by,extending
R2074 T8009 T8010 det the,end
R2075 T8010 T8008 pobj end,by
R2076 T8011 T8010 prep of,end
R2077 T8012 T8013 det the,day
R2078 T8013 T8011 pobj day,of
R2079 T8014 T8013 amod first,day
R2080 T8015 T7999 cc and,began
R2081 T8016 T8017 advmod consistently,displayed
R2082 T8017 T7999 conj displayed,began
R2083 T8018 T8019 det a,chemoattraction
R2084 T8019 T8017 dobj chemoattraction,displayed
R2085 T8020 T8019 amod strong,chemoattraction
R2086 T8021 T8017 prep by,displayed
R2087 T8022 T8023 nummod 3,d
R2088 T8023 T8021 pobj d,by
R2089 T8024 T8025 advmod in,vitro
R2090 T8025 T8023 advmod vitro,d
R2091 T8026 T8017 punct ", ",displayed
R2092 T8027 T8028 mark whereas,show
R2093 T8028 T8017 advcl show,displayed
R2094 T8029 T8028 nsubj they,show
R2095 T8030 T8028 aux did,show
R2096 T8031 T8028 neg not,show
R2097 T8032 T8033 amod such,preference
R2098 T8033 T8028 dobj preference,show
R2099 T8034 T8033 prep for,preference
R2100 T8035 T8036 npadvmod BSA,loaded
R2101 T8036 T8038 amod loaded,beads
R2102 T8037 T8036 punct -,loaded
R2103 T8038 T8034 pobj beads,for
R2104 T8039 T8038 compound control,beads
R2105 T8040 T8041 punct (,5A
R2106 T8041 T8017 parataxis 5A,displayed
R2107 T8042 T8041 compound Figure,5A
R2108 T8043 T8041 cc and,5A
R2109 T8044 T8041 conj 5B,5A
R2110 T8045 T8041 punct ),5A
R2111 T8046 T7999 punct .,began
R2112 T8048 T8049 det This,attraction
R2113 T8049 T8050 nsubj attraction,was
R2114 T8051 T8050 neg not,was
R2115 T8052 T8050 prep due,was
R2116 T8053 T8052 pcomp to,due
R2117 T8054 T8055 compound survival,support
R2118 T8055 T8052 pobj support,due
R2119 T8056 T8055 prep of,support
R2120 T8057 T8056 pobj NT,of
R2121 T8058 T8057 punct -,NT
R2122 T8059 T8057 nummod 3,NT
R2123 T8060 T8061 mark because,displayed
R2124 T8061 T8050 advcl displayed,was
R2125 T8062 T8063 npadvmod Bax,null
R2126 T8063 T8064 amod null,ganglia
R2127 T8064 T8061 nsubj ganglia,displayed
R2128 T8065 T8066 det the,chemoattraction
R2129 T8066 T8061 dobj chemoattraction,displayed
R2130 T8067 T8066 amod same,chemoattraction
R2131 T8068 T8069 punct (,5C
R2132 T8069 T8050 parataxis 5C,was
R2133 T8070 T8069 compound Figure,5C
R2134 T8071 T8069 punct ;,5C
R2135 T8072 T8073 nsubj n,16
R2136 T8073 T8069 ccomp 16,5C
R2137 T8074 T8073 punct =,16
R2138 T8075 T8069 punct ),5C
R2139 T8076 T8050 punct .,was
R2140 T8078 T8079 nsubj NT,act
R2141 T8080 T8078 punct -,NT
R2142 T8081 T8078 nummod 3,NT
R2143 T8082 T8079 aux may,act
R2144 T8083 T8079 prep through,act
R2145 T8084 T8085 preconj either,TrkC
R2146 T8085 T8083 pobj TrkC,through
R2147 T8086 T8085 punct ", ",TrkC
R2148 T8087 T8085 cc or,TrkC
R2149 T8088 T8089 det the,p75NTR
R2150 T8089 T8085 conj p75NTR,TrkC
R2151 T8090 T8079 punct .,act
R2152 T8092 T8093 nsubj We,repeated
R2153 T8094 T8095 det the,experiments
R2154 T8095 T8093 dobj experiments,repeated
R2155 T8096 T8095 compound co-culture,experiments
R2156 T8097 T8093 prep with,repeated
R2157 T8098 T8099 compound DRG,explants
R2158 T8099 T8097 pobj explants,with
R2159 T8100 T8099 acl derived,explants
R2160 T8101 T8100 prep from,derived
R2161 T8102 T8103 compound p75NTR,KO
R2162 T8103 T8104 compound KO,mice
R2163 T8104 T8101 pobj mice,from
R2164 T8105 T8106 punct (,18
R2165 T8106 T8093 parataxis 18,repeated
R2166 T8107 T8106 nsubj n,18
R2167 T8108 T8106 punct =,18
R2168 T8109 T8106 punct ),18
R2169 T8110 T8093 punct .,repeated
R2170 T8112 T8113 nsubj Axons,showed
R2171 T8114 T8112 prep of,Axons
R2172 T8115 T8116 det these,ganglia
R2173 T8116 T8114 pobj ganglia,of
R2174 T8117 T8113 advmod also,showed
R2175 T8118 T8119 amod strong,chemoattraction
R2176 T8119 T8113 dobj chemoattraction,showed
R2177 T8120 T8119 prep towards,chemoattraction
R2178 T8121 T8122 det the,beads
R2179 T8122 T8120 pobj beads,towards
R2180 T8123 T8122 nmod NT,beads
R2181 T8124 T8123 punct -,NT
R2182 T8125 T8123 nummod 3,NT
R2183 T8126 T8127 punct (,5D
R2184 T8127 T8113 parataxis 5D,showed
R2185 T8128 T8127 compound Figure,5D
R2186 T8129 T8127 punct ),5D
R2187 T8130 T8113 punct .,showed
R2188 T8132 T8133 advmod Finally,used
R2189 T8134 T8133 punct ", ",used
R2190 T8135 T8133 nsubj we,used
R2191 T8136 T8137 amod diffusible,receptors
R2192 T8137 T8133 dobj receptors,used
R2193 T8138 T8137 compound TrkC,receptors
R2194 T8139 T8137 acl conjugated,receptors
R2195 T8140 T8139 prep to,conjugated
R2196 T8141 T8142 compound IgG,regions
R2197 T8142 T8140 pobj regions,to
R2198 T8143 T8142 compound constant,regions
R2199 T8144 T8145 punct (,Fc
R2200 T8145 T8142 parataxis Fc,regions
R2201 T8146 T8145 compound TrkC,Fc
R2202 T8147 T8145 punct -,Fc
R2203 T8148 T8145 punct ),Fc
R2204 T8149 T8142 acl added,regions
R2205 T8150 T8149 prep to,added
R2206 T8151 T8152 det the,medium
R2207 T8152 T8150 pobj medium,to
R2208 T8153 T8154 punct (,6
R2209 T8154 T8149 parataxis 6,added
R2210 T8155 T8154 nsubj n,6
R2211 T8156 T8154 punct =,6
R2212 T8157 T8154 punct ),6
R2213 T8158 T8159 aux to,deplete
R2214 T8159 T8133 advcl deplete,used
R2215 T8160 T8161 amod soluble,NT
R2216 T8161 T8159 dobj NT,deplete
R2217 T8162 T8161 punct -,NT
R2218 T8163 T8161 nummod 3,NT
R2219 T8164 T8159 prep from,deplete
R2220 T8165 T8166 det the,gels
R2221 T8166 T8164 pobj gels,from
R2222 T8167 T8166 compound collagen,gels
R2223 T8168 T8169 punct (,5E
R2224 T8169 T8133 parataxis 5E,used
R2225 T8170 T8169 compound Figure,5E
R2226 T8171 T8169 punct ),5E
R2227 T8172 T8133 punct .,used
R2228 T8174 T8175 prep In,blocked
R2229 T8176 T8177 det the,presence
R2230 T8177 T8174 pobj presence,In
R2231 T8178 T8177 prep of,presence
R2232 T8179 T8180 compound TrkC,Fc
R2233 T8180 T8178 pobj Fc,of
R2234 T8181 T8180 punct -,Fc
R2235 T8182 T8183 det the,chemoattraction
R2236 T8183 T8175 nsubjpass chemoattraction,blocked
R2237 T8184 T8175 auxpass was,blocked
R2238 T8185 T8175 advmod completely,blocked
R2239 T8186 T8175 punct ", ",blocked
R2240 T8187 T8175 advcl demonstrating,blocked
R2241 T8188 T8189 mark that,is
R2242 T8189 T8187 ccomp is,demonstrating
R2243 T8190 T8191 det the,effect
R2244 T8191 T8189 nsubj effect,is
R2245 T8192 T8193 nsubj we,see
R2246 T8193 T8191 advcl see,effect
R2247 T8194 T8189 acomp specific,is
R2248 T8195 T8194 prep for,specific
R2249 T8196 T8195 pobj NT,for
R2250 T8197 T8196 punct -,NT
R2251 T8198 T8196 nummod 3,NT
R2252 T8199 T8175 punct .,blocked
R2253 T8201 T8202 prep In,repeated
R2254 T8203 T8201 pobj order,In
R2255 T8204 T8205 aux to,investigate
R2256 T8205 T8203 acl investigate,order
R2257 T8206 T8207 det the,range
R2258 T8207 T8205 dobj range,investigate
R2259 T8208 T8207 amod active,range
R2260 T8209 T8207 prep of,range
R2261 T8210 T8211 poss our,beads
R2262 T8211 T8209 pobj beads,of
R2263 T8212 T8202 punct ", ",repeated
R2264 T8213 T8202 nsubj we,repeated
R2265 T8214 T8202 aux have,repeated
R2266 T8215 T8216 det the,cultures
R2267 T8216 T8202 dobj cultures,repeated
R2268 T8217 T8202 prep with,repeated
R2269 T8218 T8219 compound WT,DRGs
R2270 T8219 T8217 pobj DRGs,with
R2271 T8220 T8219 compound E13,DRGs
R2272 T8221 T8202 prep by,repeated
R2273 T8222 T8221 pcomp placing,by
R2274 T8223 T8224 det the,beads
R2275 T8224 T8222 dobj beads,placing
R2276 T8225 T8222 prep at,placing
R2277 T8226 T8227 amod increasing,distances
R2278 T8227 T8225 pobj distances,at
R2279 T8228 T8227 prep from,distances
R2280 T8229 T8230 det the,ganglia
R2281 T8230 T8228 pobj ganglia,from
R2282 T8231 T8232 punct (,4
R2283 T8232 T8222 parataxis 4,placing
R2284 T8233 T8232 nsubj n,4
R2285 T8234 T8232 punct =,4
R2286 T8235 T8232 appos each,4
R2287 T8236 T8232 punct ),4
R2288 T8237 T8238 punct (,5F
R2289 T8238 T8222 parataxis 5F,placing
R2290 T8239 T8238 compound Figure,5F
R2291 T8240 T8238 punct ),5F
R2292 T8241 T8202 punct .,repeated
R2293 T8243 T8244 expl There,was
R2294 T8245 T8244 advmod still,was
R2295 T8246 T8247 amod preferred,growth
R2296 T8247 T8244 attr growth,was
R2297 T8248 T8247 prep towards,growth
R2298 T8249 T8250 det the,bead
R2299 T8250 T8248 pobj bead,towards
R2300 T8251 T8250 prep at,bead
R2301 T8252 T8253 nummod "1,200",μm
R2302 T8253 T8251 pobj μm,at
R2303 T8254 T8253 punct ", ",μm
R2304 T8255 T8256 det the,distance
R2305 T8256 T8253 appos distance,μm
R2306 T8257 T8256 amod longest,distance
R2307 T8258 T8256 acl studied,distance
R2308 T8259 T8244 punct ", ",was
R2309 T8260 T8261 mark although,were
R2310 T8261 T8244 advcl were,was
R2311 T8262 T8263 det the,number
R2312 T8263 T8261 nsubj number,were
R2313 T8264 T8263 prep of,number
R2314 T8265 T8264 pobj axons,of
R2315 T8266 T8263 cc and,number
R2316 T8267 T8268 det the,extent
R2317 T8268 T8263 conj extent,number
R2318 T8269 T8268 prep of,extent
R2319 T8270 T8269 pobj growth,of
R2320 T8271 T8261 neg not,were
R2321 T8272 T8273 advmod as,robust
R2322 T8273 T8261 acomp robust,were
R2323 T8274 T8244 punct .,was
R2324 T8276 T8277 advmod Next,set
R2325 T8278 T8277 punct ", ",set
R2326 T8279 T8277 nsubj we,set
R2327 T8280 T8277 prt up,set
R2328 T8281 T8282 nmod E13,cultures
R2329 T8282 T8277 dobj cultures,set
R2330 T8283 T8282 nmod DRG,cultures
R2331 T8284 T8285 amod spinal,cord
R2332 T8285 T8282 compound cord,cultures
R2333 T8286 T8282 compound explant,cultures
R2334 T8287 T8277 advcl using,set
R2335 T8288 T8289 npadvmod NT,loaded
R2336 T8289 T8293 amod loaded,beads
R2337 T8290 T8288 punct -,NT
R2338 T8291 T8288 nummod 3,NT
R2339 T8292 T8289 punct -,loaded
R2340 T8293 T8287 dobj beads,using
R2341 T8294 T8293 acl placed,beads
R2342 T8295 T8294 prep at,placed
R2343 T8296 T8297 det the,midline
R2344 T8297 T8295 pobj midline,at
R2345 T8298 T8297 prep at,midline
R2346 T8299 T8300 amod mid-spinal,level
R2347 T8300 T8298 pobj level,at
R2348 T8301 T8300 compound cord,level
R2349 T8302 T8287 prep as,using
R2350 T8303 T8304 det an,source
R2351 T8304 T8302 pobj source,as
R2352 T8305 T8304 amod ectopic,source
R2353 T8306 T8304 nmod NT,source
R2354 T8307 T8306 punct -,NT
R2355 T8308 T8306 nummod 3,NT
R2356 T8309 T8310 punct (,15
R2357 T8310 T8277 parataxis 15,set
R2358 T8311 T8310 nsubj n,15
R2359 T8312 T8310 punct =,15
R2360 T8313 T8310 punct ),15
R2361 T8314 T8277 punct .,set
R2362 T8316 T8317 compound Control,cultures
R2363 T8317 T8318 nsubjpass cultures,set
R2364 T8319 T8318 auxpass were,set
R2365 T8320 T8318 advcl using,set
R2366 T8321 T8322 npadvmod PBS,loaded
R2367 T8322 T8324 amod loaded,beads
R2368 T8323 T8322 punct -,loaded
R2369 T8324 T8320 dobj beads,using
R2370 T8325 T8326 punct (,6
R2371 T8326 T8320 parataxis 6,using
R2372 T8327 T8326 nsubj n,6
R2373 T8328 T8326 punct =,6
R2374 T8329 T8326 punct ),6
R2375 T8330 T8318 punct .,set
R2376 T8332 T8333 compound DiI,labeling
R2377 T8333 T8334 nsubj labeling,revealed
R2378 T8335 T8333 prep through,labeling
R2379 T8336 T8337 det the,DRGs
R2380 T8337 T8335 pobj DRGs,through
R2381 T8338 T8339 amod numerous,fibers
R2382 T8339 T8334 dobj fibers,revealed
R2383 T8340 T8339 acl entering,fibers
R2384 T8341 T8342 det the,cord
R2385 T8342 T8340 dobj cord,entering
R2386 T8343 T8342 amod spinal,cord
R2387 T8344 T8340 prep at,entering
R2388 T8345 T8346 amod ectopic,regions
R2389 T8346 T8344 pobj regions,at
R2390 T8347 T8340 cc and,entering
R2391 T8348 T8340 conj growing,entering
R2392 T8349 T8348 prep towards,growing
R2393 T8350 T8351 det the,beads
R2394 T8351 T8349 pobj beads,towards
R2395 T8352 T8351 nmod NT,beads
R2396 T8353 T8352 punct -,NT
R2397 T8354 T8352 nummod 3,NT
R2398 T8355 T8356 punct (,6A
R2399 T8356 T8349 parataxis 6A,towards
R2400 T8357 T8356 compound Figure,6A
R2401 T8358 T8356 punct ),6A
R2402 T8359 T8340 punct ", ",entering
R2403 T8360 T8340 dep surrounding,entering
R2404 T8361 T8362 det the,beads
R2405 T8362 T8360 dobj beads,surrounding
R2406 T8363 T8360 cc and,surrounding
R2407 T8364 T8360 conj forming,surrounding
R2408 T8365 T8364 dobj bundles,forming
R2409 T8366 T8364 prep around,forming
R2410 T8367 T8366 pobj them,around
R2411 T8368 T8369 punct (,6C
R2412 T8369 T8334 parataxis 6C,revealed
R2413 T8370 T8369 compound Figure,6C
R2414 T8371 T8372 punct –,6E
R2415 T8372 T8369 prep 6E,6C
R2416 T8373 T8369 punct ),6C
R2417 T8374 T8334 punct .,revealed
R2418 T8376 T8377 prep In,directed
R2419 T8378 T8379 compound control,cultures
R2420 T8379 T8376 pobj cultures,In
R2421 T8380 T8377 punct ", ",directed
R2422 T8381 T8382 det all,fibers
R2423 T8382 T8377 nsubjpass fibers,directed
R2424 T8383 T8382 amod labeled,fibers
R2425 T8384 T8377 auxpass were,directed
R2426 T8385 T8377 prep towards,directed
R2427 T8386 T8387 det the,cord
R2428 T8387 T8385 pobj cord,towards
R2429 T8388 T8387 amod dorsal,cord
R2430 T8389 T8387 amod spinal,cord
R2431 T8390 T8377 cc and,directed
R2432 T8391 T8377 conj terminated,directed
R2433 T8392 T8391 advmod there,terminated
R2434 T8393 T8391 punct ", ",terminated
R2435 T8394 T8395 advmod where,enter
R2436 T8395 T8391 advcl enter,terminated
R2437 T8396 T8395 nsubj they,enter
R2438 T8397 T8395 advmod normally,enter
R2439 T8398 T8399 det the,matter
R2440 T8399 T8395 dobj matter,enter
R2441 T8400 T8399 amod gray,matter
R2442 T8401 T8395 prep at,enter
R2443 T8402 T8401 pobj E13,at
R2444 T8403 T8404 punct (,6B
R2445 T8404 T8391 parataxis 6B,terminated
R2446 T8405 T8404 compound Figure,6B
R2447 T8406 T8404 punct ),6B
R2448 T8407 T8377 punct .,directed
R2449 T8409 T8410 det No,axons
R2450 T8410 T8411 nsubjpass axons,observed
R2451 T8412 T8411 auxpass were,observed
R2452 T8413 T8411 prep around,observed
R2453 T8414 T8415 det the,beads
R2454 T8415 T8413 pobj beads,around
R2455 T8416 T8417 npadvmod PBS,loaded
R2456 T8417 T8415 amod loaded,beads
R2457 T8418 T8417 punct -,loaded
R2458 T8419 T8415 compound control,beads
R2459 T8420 T8421 punct (,6F
R2460 T8421 T8411 parataxis 6F,observed
R2461 T8422 T8421 compound Figure,6F
R2462 T8423 T8421 punct ),6F
R2463 T8424 T8411 punct .,observed
R2464 T8426 T8427 nsubj Axons,grow
R2465 T8428 T8429 dep that,enter
R2466 T8429 T8426 relcl enter,Axons
R2467 T8430 T8429 advmod normally,enter
R2468 T8431 T8432 det the,matter
R2469 T8432 T8429 dobj matter,enter
R2470 T8433 T8432 amod gray,matter
R2471 T8434 T8429 prep through,enter
R2472 T8435 T8436 amod dorsal,cord
R2473 T8436 T8434 pobj cord,through
R2474 T8437 T8436 amod spinal,cord
R2475 T8438 T8427 prep towards,grow
R2476 T8439 T8440 det the,midline
R2477 T8440 T8438 pobj midline,towards
R2478 T8441 T8442 advmod when,presented
R2479 T8442 T8427 advcl presented,grow
R2480 T8443 T8442 prep with,presented
R2481 T8444 T8445 det a,source
R2482 T8445 T8443 pobj source,with
R2483 T8446 T8445 amod localized,source
R2484 T8447 T8445 nmod NT,source
R2485 T8448 T8447 punct -,NT
R2486 T8449 T8447 nummod 3,NT
R2487 T8450 T8427 punct ", ",grow
R2488 T8451 T8427 cc and,grow
R2489 T8452 T8453 amod new,growth
R2490 T8453 T8455 nsubjpass growth,initiated
R2491 T8454 T8453 compound axon,growth
R2492 T8455 T8427 conj initiated,grow
R2493 T8456 T8453 prep towards,growth
R2494 T8457 T8458 det the,bead
R2495 T8458 T8456 pobj bead,towards
R2496 T8459 T8458 nmod NT,bead
R2497 T8460 T8459 punct -,NT
R2498 T8461 T8459 nummod 3,NT
R2499 T8462 T8455 auxpass is,initiated
R2500 T8463 T8455 prep from,initiated
R2501 T8464 T8463 pobj DRGs,from
R2502 T8465 T8455 punct ", ",initiated
R2503 T8466 T8455 advcl entering,initiated
R2504 T8467 T8468 det the,cord
R2505 T8468 T8466 dobj cord,entering
R2506 T8469 T8468 amod spinal,cord
R2507 T8470 T8466 prep at,entering
R2508 T8471 T8472 amod ectopic,loci
R2509 T8472 T8470 pobj loci,at
R2510 T8473 T8466 prep at,entering
R2511 T8474 T8475 amod lateral,cord
R2512 T8475 T8473 pobj cord,at
R2513 T8476 T8475 amod mid-spinal,cord
R2514 T8477 T8478 punct (,6G
R2515 T8478 T8466 parataxis 6G,entering
R2516 T8479 T8478 compound Figure,6G
R2517 T8480 T8478 punct ),6G
R2518 T8481 T8455 punct .,initiated
R2519 T8483 T8484 nsubj NT,is
R2520 T8485 T8483 punct -,NT
R2521 T8486 T8483 nummod 3,NT
R2522 T8487 T8484 advmod therefore,is
R2523 T8488 T8484 acomp capable,is
R2524 T8489 T8488 prep of,capable
R2525 T8490 T8489 pcomp acting,of
R2526 T8491 T8490 prep as,acting
R2527 T8492 T8493 det a,chemoattractant
R2528 T8493 T8491 pobj chemoattractant,as
R2529 T8494 T8493 prep for,chemoattractant
R2530 T8495 T8496 compound DRG,axons
R2531 T8496 T8494 pobj axons,for
R2532 T8497 T8484 punct .,is
R2541 T13466 T13463 pobj cultures,in
R2542 T13384 T13385 advmod Relatively,studies
R2543 T13385 T13387 nsubj studies,implicated
R2544 T13386 T13385 amod few,studies
R2545 T13388 T13387 aux have,implicated
R2546 T13389 T13387 dobj NT,implicated
R2547 T13390 T13389 punct -,NT
R2548 T13391 T13389 nummod 3,NT
R2549 T13392 T13387 prep as,implicated
R2550 T13393 T13394 det a,agent
R2551 T13394 T13392 pobj agent,as
R2552 T13395 T13394 amod chemoattractant,agent
R2553 T13396 T13394 prep for,agent
R2554 T13397 T13398 amod sensory,axons
R2555 T13398 T13396 pobj axons,for
R2556 T13399 T13397 cc and,sensory
R2557 T13400 T13397 conj motor,sensory
R2558 T13401 T13387 punct .,implicated
R2559 T13467 T13457 advmod preferentially,grow
R2560 T13403 T13404 advmod Previously,noted
R2561 T13404 T13405 amod noted,action
R2562 T13468 T13457 prep towards,grow
R2563 T13405 T13407 nsubjpass action,attributed
R2564 T13406 T13405 compound chemoattractant,action
R2565 T13408 T13405 prep of,action
R2566 T13469 T13470 npadvmod neurotrophin,soaked
R2567 T13409 T13410 det the,process
R2568 T13410 T13408 pobj process,of
R2569 T13411 T13412 amod embryonic,mouse
R2570 T13470 T13472 amod soaked,beads
R2571 T13412 T13410 nmod mouse,process
R2572 T13413 T13410 amod maxillary,process
R2573 T13471 T13470 punct -,soaked
R2574 T13414 T13410 prep on,process
R2575 T13415 T13416 amod trigeminal,neurons
R2576 T13416 T13414 pobj neurons,on
R2577 T13417 T13416 compound ganglion,neurons
R2578 T13472 T13468 pobj beads,towards
R2579 T13418 T13419 punct (,Lumsden
R2580 T13419 T13405 meta Lumsden,action
R2581 T13420 T13419 cc and,Lumsden
R2582 T13473 T13474 advmod instead,of
R2583 T13421 T13419 conj Davies,Lumsden
R2584 T13422 T13421 nummod 1986,Davies
R2585 T13423 T13421 punct ),Davies
R2586 T13424 T13407 auxpass is,attributed
R2587 T13425 T13407 advmod now,attributed
R2588 T13426 T13407 prep to,attributed
R2589 T13427 T13426 pobj NT,to
R2590 T13474 T13457 prep of,grow
R2591 T13428 T13427 punct -,NT
R2592 T13429 T13427 nummod 3,NT
R2593 T13475 T13474 pcomp following,of
R2594 T13430 T13427 cc and,NT
R2595 T13431 T13432 npadvmod brain,derived
R2596 T13476 T13477 poss their,trajectories
R2597 T13432 T13434 amod derived,factor
R2598 T13433 T13432 punct -,derived
R2599 T13434 T13427 conj factor,NT
R2600 T13477 T13475 dobj trajectories,following
R2601 T13435 T13434 amod neurotrophic,factor
R2602 T13436 T13434 punct (,factor
R2603 T13478 T13477 amod normal,trajectories
R2604 T13437 T13434 appos BDNF,factor
R2605 T13438 T13407 punct ),attributed
R2606 T13439 T13440 punct (,O'Connor
R2607 T13440 T13407 meta O'Connor,attributed
R2608 T13441 T13440 nmod et,O'Connor
R2609 T13479 T13448 punct .,showed
R2610 T13442 T13440 nmod al.,O'Connor
R2611 T13443 T13440 nummod 1999,O'Connor
R2612 T13444 T13440 punct ),O'Connor
R2613 T13481 T13482 advmod Conversely,led
R2614 T13445 T13407 punct .,attributed
R2615 T13447 T13448 advmod Recently,showed
R2616 T13483 T13482 punct ", ",led
R2617 T13449 T13448 punct ", ",showed
R2618 T13450 T13448 nsubj Tucker,showed
R2619 T13451 T13452 advmod et,al.
R2620 T13484 T13482 nsubj beads,led
R2621 T13452 T13450 advmod al.,Tucker
R2622 T13453 T13450 punct (,Tucker
R2623 T13454 T13450 npadvmod 2001,Tucker
R2624 T13485 T13484 acl soaked,beads
R2625 T13455 T13450 punct ),Tucker
R2626 T13456 T13457 mark that,grow
R2627 T13457 T13448 ccomp grow,showed
R2628 T13458 T13459 amod developing,axons
R2629 T13486 T13485 prep with,soaked
R2630 T13459 T13457 nsubj axons,grow
R2631 T13460 T13459 amod sensory,axons
R2632 T13461 T13460 cc and,sensory
R2633 T13487 T13488 nmod neurotrophin,antibodies
R2634 T13462 T13460 conj motor,sensory
R2635 T13463 T13459 prep in,axons
R2636 T13464 T13465 compound limb,slice
R2637 T13465 T13466 compound slice,cultures
R2638 T13488 T13486 pobj antibodies,with
R2639 T13489 T13490 npadvmod function,blocking
R2640 T13490 T13488 amod blocking,antibodies
R2641 T13572 T13571 compound chemoattractant,role
R2642 T13573 T13565 prep during,play
R2643 T13491 T13490 punct -,blocking
R2644 T13574 T13575 det the,innervation
R2645 T13575 T13573 pobj innervation,during
R2646 T13492 T13482 prep to,led
R2647 T13576 T13575 prep of,innervation
R2648 T13577 T13578 amod ventral,horns
R2649 T13578 T13576 pobj horns,of
R2650 T13493 T13492 pobj reduction,to
R2651 T13579 T13575 prep by,innervation
R2652 T13580 T13581 amod proprioceptive,afferents
R2653 T13494 T13493 prep of,reduction
R2654 T13581 T13579 pobj afferents,by
R2655 T13582 T13559 punct .,considered
R2656 T13495 T13496 amod sensory,growth
R2657 T13584 T13585 advmod However,led
R2658 T13586 T13585 punct ", ",led
R2659 T13496 T13494 pobj growth,of
R2660 T13587 T13588 amod earlier,findings
R2661 T13588 T13585 nsubj findings,led
R2662 T13497 T13495 cc and,sensory
R2663 T13589 T13588 prep of,findings
R2664 T13590 T13591 amod normal,trajectories
R2665 T13498 T13495 conj motor,sensory
R2666 T13591 T13589 pobj trajectories,of
R2667 T13499 T13496 compound axon,growth
R2668 T13592 T13591 amod proprioceptive,trajectories
R2669 T13593 T13591 amod afferent,trajectories
R2670 T13594 T13591 prep in,trajectories
R2671 T13500 T13496 prep towards,growth
R2672 T13595 T13596 compound chicken,embryos
R2673 T13596 T13594 pobj embryos,in
R2674 T13501 T13502 det the,limb
R2675 T13597 T13588 prep despite,findings
R2676 T13598 T13597 pobj injection,despite
R2677 T13599 T13598 prep of,injection
R2678 T13502 T13500 pobj limb,towards
R2679 T13600 T13601 npadvmod function,blocking
R2680 T13601 T13603 amod blocking,antibody
R2681 T13503 T13482 punct .,led
R2682 T13602 T13601 punct -,blocking
R2683 T13505 T13506 prep In,altered
R2684 T13603 T13599 pobj antibody,of
R2685 T13604 T13603 nmod NT,antibody
R2686 T13605 T13604 punct -,NT
R2687 T13606 T13604 nummod 3,NT
R2688 T13607 T13598 prep into,injection
R2689 T13608 T13609 det the,cord
R2690 T13609 T13607 pobj cord,into
R2691 T13610 T13609 amod spinal,cord
R2692 T13611 T13612 punct (,Oakley
R2693 T13612 T13588 meta Oakley,findings
R2694 T13507 T13508 amod transgenic,mice
R2695 T13613 T13612 nmod et,Oakley
R2696 T13614 T13612 nmod al.,Oakley
R2697 T13615 T13612 nummod 1995,Oakley
R2698 T13616 T13612 punct ),Oakley
R2699 T13617 T13585 dobj them,led
R2700 T13508 T13505 pobj mice,In
R2701 T13618 T13619 aux to,discount
R2702 T13619 T13585 xcomp discount,led
R2703 T13620 T13621 det this,possibility
R2704 T13621 T13619 dobj possibility,discount
R2705 T13509 T13508 punct ", ",mice
R2706 T13622 T13585 punct .,led
R2707 T13624 T13625 prep In,showed
R2708 T13510 T13511 dep which,over-express
R2709 T13626 T13627 det that,study
R2710 T13511 T13508 relcl over-express,mice
R2711 T13627 T13624 pobj study,In
R2712 T13628 T13625 punct ", ",showed
R2713 T13629 T13625 advmod though,showed
R2714 T13512 T13511 dobj NT,over-express
R2715 T13630 T13625 punct ", ",showed
R2716 T13631 T13625 nsubj assays,showed
R2717 T13632 T13631 prep on,assays
R2718 T13513 T13512 punct -,NT
R2719 T13633 T13634 det the,effectiveness
R2720 T13634 T13632 pobj effectiveness,on
R2721 T13514 T13512 nummod 3,NT
R2722 T13635 T13634 prep of,effectiveness
R2723 T13636 T13637 compound antibody,perturbation
R2724 T13637 T13635 pobj perturbation,of
R2725 T13638 T13634 prep on,effectiveness
R2726 T13515 T13511 prep under,over-express
R2727 T13639 T13640 npadvmod NT,dependent
R2728 T13640 T13644 amod dependent,survival
R2729 T13516 T13517 det the,promoter
R2730 T13641 T13639 punct -,NT
R2731 T13642 T13639 nummod 3,NT
R2732 T13643 T13640 punct -,dependent
R2733 T13517 T13515 pobj promoter,under
R2734 T13644 T13638 pobj survival,on
R2735 T13645 T13644 compound cell,survival
R2736 T13646 T13647 mark that,was
R2737 T13518 T13517 compound nestin,promoter
R2738 T13647 T13625 ccomp was,showed
R2739 T13648 T13647 nsubj effectiveness,was
R2740 T13649 T13647 acomp significant,was
R2741 T13650 T13651 punct (,%
R2742 T13651 T13649 parataxis %,significant
R2743 T13652 T13653 advmod approximately,90
R2744 T13519 T13511 prep in,over-express
R2745 T13653 T13651 nummod 90,%
R2746 T13654 T13651 punct ),%
R2747 T13655 T13649 cc but,significant
R2748 T13520 T13521 det the,system
R2749 T13656 T13655 neg not,but
R2750 T13657 T13649 conj complete,significant
R2751 T13658 T13659 punct (,Oakley
R2752 T13521 T13519 pobj system,in
R2753 T13659 T13625 meta Oakley,showed
R2754 T13660 T13659 nmod et,Oakley
R2755 T13661 T13659 nmod al.,Oakley
R2756 T13522 T13521 amod central,system
R2757 T13662 T13659 nummod 1995,Oakley
R2758 T13663 T13659 punct ),Oakley
R2759 T13664 T13625 punct .,showed
R2760 T13523 T13521 amod nervous,system
R2761 T13666 T13667 nsubj Ringstedt,argue
R2762 T13524 T13506 punct ", ",altered
R2763 T13668 T13669 advmod et,al.
R2764 T13669 T13666 advmod al.,Ringstedt
R2765 T13525 T13526 det the,course
R2766 T13670 T13666 punct (,Ringstedt
R2767 T13671 T13666 npadvmod 1997,Ringstedt
R2768 T13672 T13666 punct ),Ringstedt
R2769 T13673 T13674 mark that,disrupts
R2770 T13526 T13506 nsubjpass course,altered
R2771 T13527 T13526 prep of,course
R2772 T13674 T13667 ccomp disrupts,argue
R2773 T13675 T13676 mark while,navigate
R2774 T13528 T13529 det the,afferents
R2775 T13676 T13674 advcl navigate,disrupts
R2776 T13529 T13527 pobj afferents,of
R2777 T13530 T13529 amod proprioceptive,afferents
R2778 T13531 T13506 auxpass are,altered
R2779 T13677 T13678 amod central,axons
R2780 T13678 T13676 nsubj axons,navigate
R2781 T13532 T13506 cc and,altered
R2782 T13679 T13678 amod sensory,axons
R2783 T13680 T13676 aux may,navigate
R2784 T13681 T13676 advmod still,navigate
R2785 T13533 T13506 conj directed,altered
R2786 T13682 T13676 advmod properly,navigate
R2787 T13683 T13676 prep in,navigate
R2788 T13534 T13533 prep towards,directed
R2789 T13684 T13685 det the,absence
R2790 T13535 T13536 det the,regions
R2791 T13685 T13683 pobj absence,in
R2792 T13686 T13685 prep of,absence
R2793 T13687 T13686 pobj NT,of
R2794 T13688 T13687 punct -,NT
R2795 T13689 T13687 nummod 3,NT
R2796 T13690 T13674 punct ", ",disrupts
R2797 T13691 T13692 amod ectopic,expression
R2798 T13692 T13674 nsubj expression,disrupts
R2799 T13536 T13534 pobj regions,towards
R2800 T13693 T13692 prep of,expression
R2801 T13694 T13693 pobj NT,of
R2802 T13695 T13694 punct -,NT
R2803 T13537 T13536 prep with,regions
R2804 T13696 T13694 nummod 3,NT
R2805 T13697 T13698 poss their,targeting
R2806 T13698 T13674 dobj targeting,disrupts
R2807 T13538 T13539 amod high,levels
R2808 T13699 T13667 punct .,argue
R2809 T13539 T13537 pobj levels,with
R2810 T13701 T13702 advmod Recently,suggested
R2811 T13703 T13702 punct ", ",suggested
R2812 T13540 T13539 prep of,levels
R2813 T13704 T13705 det another,member
R2814 T13705 T13702 nsubjpass member,suggested
R2815 T13706 T13705 prep of,member
R2816 T13541 T13542 amod ectopic,expression
R2817 T13707 T13708 det the,family
R2818 T13708 T13706 pobj family,of
R2819 T13709 T13708 compound neurotrophin,family
R2820 T13542 T13540 pobj expression,of
R2821 T13710 T13705 punct ", ",member
R2822 T13711 T13705 appos BDNF,member
R2823 T13712 T13702 punct ", ",suggested
R2824 T13543 T13542 nmod NT,expression
R2825 T13713 T13702 aux has,suggested
R2826 T13714 T13702 auxpass been,suggested
R2827 T13715 T13716 aux to,act
R2828 T13544 T13543 punct -,NT
R2829 T13716 T13702 xcomp act,suggested
R2830 T13717 T13716 prep as,act
R2831 T13545 T13543 nummod 3,NT
R2832 T13546 T13536 prep in,regions
R2833 T13547 T13548 det the,cord
R2834 T13718 T13719 det a,chemoattractant
R2835 T13548 T13546 pobj cord,in
R2836 T13719 T13717 pobj chemoattractant,as
R2837 T13720 T13719 prep for,chemoattractant
R2838 T13721 T13722 amod sensory,axons
R2839 T13549 T13548 amod spinal,cord
R2840 T13722 T13723 nmod axons,ear
R2841 T13723 T13720 pobj ear,for
R2842 T13724 T13723 amod innervating,ear
R2843 T13725 T13726 punct (,Tessarollo
R2844 T13726 T13702 meta Tessarollo,suggested
R2845 T13550 T13551 punct (,Ringstedt
R2846 T13727 T13726 nmod et,Tessarollo
R2847 T13728 T13726 nmod al.,Tessarollo
R2848 T13729 T13726 nummod 2004,Tessarollo
R2849 T13730 T13726 punct ),Tessarollo
R2850 T13551 T13533 meta Ringstedt,directed
R2851 T13731 T13702 punct .,suggested
R2852 T13733 T13734 prep In,rerouted
R2853 T13552 T13551 nmod et,Ringstedt
R2854 T13735 T13736 det a,strategy
R2855 T13553 T13551 nmod al.,Ringstedt
R2856 T13736 T13733 pobj strategy,In
R2857 T13737 T13738 compound gene,replacement
R2858 T13738 T13736 compound replacement,strategy
R2859 T13554 T13551 nummod 1997,Ringstedt
R2860 T13739 T13740 prep in,driven
R2861 T13740 T13736 relcl driven,strategy
R2862 T13741 T13739 pobj which,in
R2863 T13555 T13551 punct ),Ringstedt
R2864 T13742 T13743 compound BDNF,expression
R2865 T13743 T13740 nsubjpass expression,driven
R2866 T13744 T13740 auxpass was,driven
R2867 T13556 T13506 punct .,altered
R2868 T13745 T13740 agent by,driven
R2869 T13746 T13747 det the,promoter
R2871 T13558 T13559 nsubj Ringstedt,considered
R2872 T13748 T13747 nmod NT,promoter
R2873 T13749 T13748 punct -,NT
R2874 T13750 T13748 nummod 3,NT
R2875 T13751 T13734 punct ", ",rerouted
R2876 T13560 T13561 advmod et,al.
R2877 T13752 T13753 amod vestibular,axons
R2878 T13753 T13734 nsubj axons,rerouted
R2879 T13754 T13734 prep towards,rerouted
R2880 T13755 T13756 amod ectopic,sources
R2881 T13561 T13558 advmod al.,Ringstedt
R2882 T13756 T13754 pobj sources,towards
R2883 T13757 T13756 prep of,sources
R2884 T13758 T13757 pobj BDNF,of
R2885 T13562 T13563 det the,possibility
R2886 T13759 T13756 prep in,sources
R2887 T13760 T13761 det the,cochlea
R2888 T13563 T13559 dobj possibility,considered
R2889 T13761 T13759 pobj cochlea,in
R2890 T13762 T13763 dep that,expressed
R2891 T13564 T13565 mark that,play
R2892 T13763 T13756 relcl expressed,sources
R2893 T13565 T13563 acl play,possibility
R2894 T13764 T13763 advmod normally,expressed
R2895 T13765 T13763 dobj NT,expressed
R2896 T13766 T13765 punct -,NT
R2897 T13767 T13765 nummod 3,NT
R2898 T13768 T13734 cc and,rerouted
R2899 T13566 T13565 nsubj NT,play
R2900 T13769 T13770 auxpass were,innervated
R2901 T13770 T13734 conj innervated,rerouted
R2902 T13771 T13770 neg not,innervated
R2903 T13567 T13566 punct -,NT
R2904 T13772 T13770 agent by,innervated
R2905 T13773 T13774 det these,axons
R2906 T13774 T13772 pobj axons,by
R2907 T13568 T13566 nummod 3,NT
R2908 T13775 T13734 punct .,rerouted
R2909 T13569 T13565 aux may,play
R2910 T13777 T13778 amod Ectopic,NT
R2911 T13778 T13779 nsubj NT,induce
R2912 T13570 T13571 det a,role
R2913 T13780 T13778 punct -,NT
R2914 T13781 T13778 nummod 3,NT
R2915 T13782 T13778 acl supplied,NT
R2916 T13571 T13565 dobj role,play
R2917 T13889 T13867 punct .,are
R2918 T13783 T13782 advcl using,supplied
R2919 T13891 T13892 advmod Previously,rescued
R2920 T13784 T13785 amod osmotic,pumps
R2921 T13785 T13783 dobj pumps,using
R2922 T13786 T13785 cc and,pumps
R2923 T13787 T13788 npadvmod adenovirus,mediated
R2924 T13893 T13892 punct ", ",rescued
R2925 T13788 T13790 amod mediated,expression
R2926 T13789 T13788 punct -,mediated
R2927 T13790 T13785 conj expression,pumps
R2928 T13791 T13792 amod sensory,growth
R2929 T13894 T13895 amod normal,innervation
R2930 T13792 T13779 dobj growth,induce
R2931 T13793 T13792 compound axon,growth
R2932 T13794 T13779 prep during,induce
R2933 T13895 T13892 nsubjpass innervation,rescued
R2934 T13795 T13794 pobj regeneration,during
R2935 T13796 T13797 punct (,Zhang
R2936 T13797 T13779 meta Zhang,induce
R2937 T13896 T13897 compound motor,neuron
R2938 T13798 T13797 nmod et,Zhang
R2939 T13799 T13797 nmod al.,Zhang
R2940 T13800 T13797 nummod 1998,Zhang
R2941 T13897 T13895 compound neuron,innervation
R2942 T13801 T13797 punct ", ",Zhang
R2943 T13802 T13797 nmod Bradbury,Zhang
R2944 T13898 T13892 auxpass was,rescued
R2945 T13803 T13797 nmod et,Zhang
R2946 T13804 T13797 nmod al.,Zhang
R2947 T13805 T13797 nummod 1999,Zhang
R2948 T13806 T13797 punct ", ",Zhang
R2949 T13807 T13797 nmod Oudega,Zhang
R2950 T13808 T13797 nmod et,Zhang
R2951 T13899 T13892 prep in,rescued
R2952 T13809 T13797 nmod al.,Zhang
R2953 T13810 T13797 nummod 1999,Zhang
R2954 T13900 T13901 nmod NT,KO
R2955 T13811 T13797 punct ", ",Zhang
R2956 T13812 T13797 nmod Ramer,Zhang
R2957 T13813 T13797 nmod et,Zhang
R2958 T13901 T13904 compound KO,animals
R2959 T13814 T13797 nmod al.,Zhang
R2960 T13815 T13797 nummod 2002,Zhang
R2961 T13816 T13797 punct ),Zhang
R2962 T13902 T13900 punct -,NT
R2963 T13817 T13779 punct ", ",induce
R2964 T13818 T13779 cc and,induce
R2965 T13819 T13779 conj induce,induce
R2966 T13903 T13900 nummod 3,NT
R2967 T13820 T13821 amod axonal,plasticity
R2968 T13821 T13819 dobj plasticity,induce
R2969 T13822 T13821 prep of,plasticity
R2970 T13904 T13899 pobj animals,in
R2971 T13823 T13824 amod corticospinal,axons
R2972 T13824 T13822 pobj axons,of
R2973 T13825 T13819 prep in,induce
R2974 T13905 T13892 prep by,rescued
R2975 T13826 T13827 amod injured,cord
R2976 T13827 T13825 pobj cord,in
R2977 T13828 T13827 amod adult,cord
R2978 T13906 T13905 pcomp over-expressing,by
R2979 T13829 T13827 amod spinal,cord
R2980 T13830 T13831 punct (,Zhou
R2981 T13831 T13827 meta Zhou,cord
R2982 T13907 T13906 dobj NT,over-expressing
R2983 T13832 T13831 nmod et,Zhou
R2984 T13833 T13831 nmod al.,Zhou
R2985 T13834 T13831 nummod 2003,Zhou
R2986 T13908 T13907 punct -,NT
R2987 T13835 T13831 punct ),Zhou
R2988 T13836 T13827 punct ", ",cord
R2989 T13909 T13907 nummod 3,NT
R2990 T13837 T13838 advmod where,cross
R2991 T13838 T13827 relcl cross,cord
R2992 T13910 T13906 advmod selectively,over-expressing
R2993 T13839 T13840 det the,axons
R2994 T13840 T13838 nsubj axons,cross
R2995 T13841 T13840 amod sprouting,axons
R2996 T13911 T13906 prep in,over-expressing
R2997 T13842 T13840 prep from,axons
R2998 T13843 T13844 det the,site
R2999 T13844 T13842 pobj site,from
R3000 T13845 T13844 amod intact,site
R3001 T13912 T13913 poss their,muscles
R3002 T13846 T13847 det the,midline
R3003 T13847 T13838 dobj midline,cross
R3004 T13848 T13838 prep towards,cross
R3005 T13913 T13911 pobj muscles,in
R3006 T13849 T13850 det the,source
R3007 T13850 T13848 pobj source,towards
R3008 T13914 T13915 punct (,Wright
R3009 T13851 T13850 nmod NT,source
R3010 T13852 T13851 punct -,NT
R3011 T13915 T13892 meta Wright,rescued
R3012 T13853 T13851 nummod 3,NT
R3013 T13854 T13838 prep on,cross
R3014 T13916 T13915 nmod et,Wright
R3015 T13855 T13856 det the,side
R3016 T13856 T13854 pobj side,on
R3017 T13857 T13856 compound lesion,side
R3018 T13917 T13915 nmod al.,Wright
R3019 T13858 T13856 prep of,side
R3020 T13859 T13860 det the,cord
R3021 T13860 T13858 pobj cord,of
R3022 T13918 T13915 nummod 1997,Wright
R3023 T13861 T13860 amod spinal,cord
R3024 T13862 T13779 punct .,induce
R3025 T13919 T13915 punct ),Wright
R3026 T13864 T13865 poss Our,results
R3027 T13865 T13867 nsubj results,are
R3028 T13866 T13865 amod present,results
R3029 T13920 T13892 punct .,rescued
R3030 T13868 T13867 prep in,are
R3031 T13869 T13868 pobj agreement,in
R3032 T13922 T13923 nsubj It,appears
R3033 T13870 T13869 prep with,agreement
R3034 T13871 T13872 det these,observations
R3035 T13872 T13870 pobj observations,with
R3036 T13873 T13867 punct ", ",are
R3037 T13924 T13925 mark that,is
R3038 T13874 T13867 cc and,are
R3039 T13875 T13867 conj provide,are
R3040 T13876 T13877 amod further,evidence
R3041 T13877 T13875 dobj evidence,provide
R3043 T13878 T13879 mark that,acts
R3044 T13879 T13877 acl acts,evidence
R3045 T13880 T13879 nsubj NT,acts
R3046 T13926 T13927 amod peripheral,NT
R3047 T13881 T13880 punct -,NT
R3048 T13882 T13880 nummod 3,NT
R3049 T13883 T13879 prep as,acts
R3050 T13927 T13925 nsubj NT,is
R3051 T13884 T13885 det a,chemoattractant
R3052 T13885 T13883 pobj chemoattractant,as
R3053 T13886 T13879 prep for,acts
R3054 T13887 T13888 amod sensory,afferents
R3055 T13888 T13886 pobj afferents,for
R3056 T13928 T13927 punct -,NT
R3057 T13929 T13927 nummod 3,NT
R3058 T13995 T13994 cc and,Chen
R3059 T13930 T13927 advmod alone,NT
R3060 T13996 T13994 conj Frank,Chen
R3061 T13997 T13996 nummod 1999,Frank
R3062 T13998 T13996 punct ),Frank
R3063 T13999 T13975 punct .,raised
R3064 T13931 T13925 acomp sufficient,is
R3065 T14001 T14002 nsubj Assays,be
R3066 T13932 T13931 prep for,sufficient
R3067 T14003 T14004 aux to,determine
R3068 T14004 T14001 advcl determine,Assays
R3069 T13933 T13932 pobj rescuing,for
R3070 T14005 T14006 mark whether,is
R3071 T14006 T14004 ccomp is,determine
R3072 T14007 T14008 det any,NT
R3073 T13934 T13935 amod proprioceptive,neurons
R3074 T14008 T14006 nsubj NT,is
R3075 T14009 T14008 punct -,NT
R3076 T13935 T13933 dobj neurons,rescuing
R3077 T14010 T14008 nummod 3,NT
R3078 T14011 T14006 acomp present,is
R3079 T14012 T14006 prep in,is
R3080 T13936 T13933 prep in,rescuing
R3081 T14013 T14014 det the,horns
R3082 T14014 T14012 pobj horns,in
R3083 T14015 T14014 amod ventral,horns
R3084 T13937 T13938 nmod NT,KO
R3085 T14016 T14014 prep of,horns
R3086 T14017 T14018 det these,mice
R3087 T14018 T14016 pobj mice,of
R3088 T13938 T13941 compound KO,animals
R3089 T14019 T14002 aux would,be
R3090 T13939 T13937 punct -,NT
R3091 T14020 T14002 acomp informative,be
R3092 T13940 T13937 nummod 3,NT
R3093 T14021 T14002 punct .,be
R3094 T13941 T13936 pobj animals,in
R3095 T14023 T14024 advmod Recently,reported
R3096 T14025 T14024 punct ", ",reported
R3097 T13942 T13933 cc and,rescuing
R3098 T14026 T14024 nsubj Patel,reported
R3099 T14027 T14028 advmod et,al.
R3100 T13943 T13944 amod proper,pathfinding
R3101 T14028 T14026 advmod al.,Patel
R3102 T14029 T14026 punct (,Patel
R3103 T14030 T14026 npadvmod 2003,Patel
R3104 T14031 T14026 punct ),Patel
R3105 T14032 T14033 poss their,observations
R3106 T14033 T14024 dobj observations,reported
R3107 T13944 T13933 conj pathfinding,rescuing
R3108 T14034 T14033 prep on,observations
R3109 T14035 T14036 nmod Bax,KO
R3110 T14036 T14042 compound KO,mice
R3111 T13945 T13944 amod axonal,pathfinding
R3112 T14037 T14035 punct /,Bax
R3113 T14038 T14035 appos NT,Bax
R3114 T13946 T13944 prep in,pathfinding
R3115 T14039 T14038 punct -,NT
R3116 T14040 T14038 nummod 3,NT
R3117 T14041 T14036 amod double,KO
R3118 T14042 T14034 pobj mice,on
R3119 T14043 T14044 nsubj they,bred
R3120 T13947 T13948 det the,cord
R3121 T14044 T14042 advcl bred,mice
R3122 T14045 T14024 punct .,reported
R3123 T13948 T13946 pobj cord,in
R3124 T14047 T14048 poss Their,results
R3125 T14048 T14049 nsubj results,are
R3126 T14050 T14049 advmod significantly,are
R3127 T13949 T13948 amod spinal,cord
R3128 T14051 T14049 acomp different,are
R3129 T14052 T14051 prep from,different
R3130 T14053 T14052 pobj ours,from
R3131 T13950 T13923 punct .,appears
R3132 T14054 T14049 punct .,are
R3133 T14056 T14057 nsubj They,see
R3134 T13952 T13953 advmod However,is
R3135 T14058 T14059 det no,afferents
R3136 T14059 T14057 dobj afferents,see
R3137 T14060 T14059 amod proprioceptive,afferents
R3138 T13954 T13953 punct ", ",is
R3139 T14061 T14057 prep in,see
R3140 T14062 T14063 det the,periphery
R3141 T14063 T14061 pobj periphery,in
R3142 T14064 T14063 prep of,periphery
R3143 T13955 T13953 nsubj it,is
R3144 T14065 T14066 det the,knockouts
R3145 T14066 T14064 pobj knockouts,of
R3146 T14067 T14066 amod double,knockouts
R3147 T13956 T13953 acomp unclear,is
R3148 T14068 T14057 cc and,see
R3149 T14069 T14057 conj note,see
R3150 T14070 T14071 mark that,terminate
R3151 T13957 T13958 mark whether,is
R3152 T14071 T14069 ccomp terminate,note
R3153 T14072 T14073 amod central,afferents
R3154 T14073 T14071 nsubj afferents,terminate
R3155 T14074 T14073 amod proprioceptive,afferents
R3156 T14075 T14071 prep in,terminate
R3157 T14076 T14077 det the,cord
R3158 T14077 T14075 pobj cord,in
R3159 T14078 T14077 amod intermediate,cord
R3160 T14079 T14077 amod spinal,cord
R3161 T13958 T13953 ccomp is,is
R3162 T14080 T14071 prep without,terminate
R3163 T14081 T14080 pcomp extending,without
R3164 T14082 T14081 advmod ventrally,extending
R3165 T13959 T13958 nsubj NT,is
R3166 T14083 T14057 punct .,see
R3167 T14085 T14086 poss Their,observations
R3168 T13960 T13959 punct -,NT
R3169 T14086 T14087 nsubjpass observations,based
R3170 T14088 T14087 auxpass are,based
R3171 T13961 T13959 nummod 3,NT
R3172 T14089 T14087 prep on,based
R3173 T14090 T14091 compound PV,immunostaining
R3174 T14091 T14089 pobj immunostaining,on
R3175 T13962 T13958 acomp absent,is
R3176 T14092 T14091 cc and,immunostaining
R3177 T14093 T14094 compound DiI,labeling
R3178 T14094 T14091 conj labeling,immunostaining
R3179 T14095 T14091 prep of,immunostaining
R3180 T14096 T14097 det the,nerves
R3181 T13963 T13962 prep from,absent
R3182 T14097 T14095 pobj nerves,of
R3183 T14098 T14097 amod peripheral,nerves
R3184 T14099 T14087 punct .,based
R3185 T13964 T13965 det the,cords
R3186 T13965 T13963 pobj cords,from
R3187 T14101 T14102 nsubj We,noted
R3188 T13966 T13965 amod ventral,cords
R3189 T14103 T14104 mark that,is
R3190 T14104 T14102 ccomp is,noted
R3191 T14105 T14106 compound PV,immunolabeling
R3192 T13967 T13965 amod spinal,cords
R3193 T14106 T14104 nsubj immunolabeling,is
R3194 T14107 T14104 acomp diminished,is
R3195 T14108 T14104 prep in,is
R3196 T13968 T13965 prep of,cords
R3197 T14109 T14110 poss our,KOs
R3198 T13969 T13970 det these,animals
R3199 T13970 T13968 pobj animals,of
R3200 T13971 T13953 punct .,is
R3201 T14110 T14108 pobj KOs,in
R3202 T13973 T13974 det The,possibility
R3203 T14111 T14110 nmod Bax,KOs
R3204 T14112 T14111 punct /,Bax
R3205 T14113 T14111 appos NT,Bax
R3206 T14114 T14113 punct -,NT
R3207 T14115 T14113 nummod 3,NT
R3208 T14116 T14110 amod double,KOs
R3209 T14117 T14102 punct .,noted
R3210 T14119 T14120 prep In,noted
R3211 T13974 T13975 nsubjpass possibility,raised
R3212 T14120 T14129 ccomp noted,reveal
R3213 T14121 T14122 amod various,manipulations
R3214 T13976 T13975 aux has,raised
R3215 T14122 T14119 pobj manipulations,In
R3216 T14123 T14122 prep of,manipulations
R3217 T14124 T14125 det the,neurotrophins
R3218 T14125 T14123 pobj neurotrophins,of
R3219 T14126 T14120 nsubjpass it,noted
R3220 T13977 T13975 auxpass been,raised
R3223 T13978 T13979 mark that,transport
R3225 T14131 T14120 ccomp are,noted
R3226 T14132 T14133 amod molecular,markers
R3227 T13979 T13975 ccomp transport,raised
R3228 T14133 T14131 nsubj markers,are
R3229 T14134 T14133 prep for,markers
R3230 T14135 T14136 amod proprioceptive,axons
R3231 T13980 T13981 compound motor,neurons
R3232 T14136 T14134 pobj axons,for
R3233 T14137 T14138 amod such,as
R3234 T14138 T14136 prep as,axons
R3235 T13981 T13979 nsubj neurons,transport
R3236 T14139 T14138 pobj PV,as
R3237 T14140 T14133 cc or,markers
R3238 T14141 T14142 nmod calcitonin,peptide
R3239 T14142 T14133 conj peptide,markers
R3240 T13982 T13979 aux may,transport
R3241 T14143 T14144 npadvmod gene,related
R3242 T14144 T14142 amod related,peptide
R3243 T14145 T14144 punct -,related
R3244 T14146 T14142 prep for,peptide
R3245 T14147 T14148 nmod nerve,axons
R3246 T13983 T13979 advmod retrogradely,transport
R3247 T14148 T14146 pobj axons,for
R3248 T14149 T14150 compound growth,factor
R3249 T14150 T14151 npadvmod factor,responsive
R3250 T14151 T14148 amod responsive,axons
R3251 T13984 T13979 dobj NT,transport
R3252 T14152 T14151 punct –,responsive
R3253 T14153 T14131 acomp compromised,are
R3254 T14154 T14155 punct (,Ringstedt
R3255 T13985 T13984 punct -,NT
R3256 T14155 T14120 meta Ringstedt,noted
R3257 T14156 T14155 nmod et,Ringstedt
R3258 T14157 T14155 nmod al.,Ringstedt
R3259 T14158 T14155 nummod 1997,Ringstedt
R3260 T14159 T14155 punct ;,Ringstedt
R3261 T14160 T14155 nmod Patel,Ringstedt
R3262 T13986 T13984 nummod 3,NT
R3263 T14161 T14155 nmod et,Ringstedt
R3264 T14162 T14155 nmod al.,Ringstedt
R3265 T14163 T14155 nummod 2000,Ringstedt
R3266 T13987 T13979 prep in,transport
R3267 T14164 T14155 punct ),Ringstedt
R3268 T14165 T14129 punct ", ",reveal
R3269 T14166 T14129 advmod thus,reveal
R3270 T13988 T13987 pobj muscle,in
R3271 T14167 T14168 compound PV,immunostaining
R3272 T14168 T14129 nsubj immunostaining,reveal
R3273 T13989 T13979 prep to,transport
R3274 T14169 T14168 prep in,immunostaining
R3275 T14170 T14171 nmod Bax,KOs
R3276 T14171 T14169 pobj KOs,in
R3277 T13990 T13991 det the,cord
R3278 T14172 T14170 punct /,Bax
R3279 T14173 T14170 appos NT,Bax
R3280 T14174 T14173 punct -,NT
R3281 T13991 T13989 pobj cord,to
R3282 T14175 T14173 nummod 3,NT
R3283 T14176 T14171 amod double,KOs
R3284 T14177 T14129 aux can,reveal
R3285 T13992 T13991 amod spinal,cord
R3286 T14178 T14129 neg not,reveal
R3287 T14179 T14180 det the,extent
R3288 T14180 T14129 dobj extent,reveal
R3289 T13993 T13994 punct (,Chen
R3290 T14181 T14180 prep of,extent
R3291 T14182 T14183 amod proprioceptive,axons
R3292 T14183 T14181 pobj axons,of
R3293 T13994 T13975 meta Chen,raised
R3294 T14184 T14183 prep in,axons
R3295 T14185 T14186 det the,periphery
R3296 T14186 T14184 pobj periphery,in
R3297 T14206 T14202 prep in,expressing
R3298 T14187 T14129 punct .,reveal
R3299 T14189 T14190 compound Seventy,three
R3300 T14190 T14192 nummod three,percent
R3301 T14207 T14208 det the,DRG
R3302 T14191 T14190 punct -,three
R3303 T14192 T14193 nsubjpass percent,reported
R3304 T14208 T14206 pobj DRG,in
R3305 T14194 T14192 prep of,percent
R3306 T14195 T14196 advmod retrogradely,labeled
R3307 T14209 T14208 amod adult,DRG
R3308 T14196 T14197 amod labeled,afferents
R3309 T14210 T14208 compound rat,DRG
R3310 T14197 T14194 pobj afferents,of
R3311 T14198 T14199 compound gastrocnemius,muscle
R3312 T14199 T14197 compound muscle,afferents
R3313 T14200 T14193 auxpass were,reported
R3314 T14201 T14202 aux to,expressing
R3315 T14202 T14193 xcomp expressing,reported
R3316 T14211 T14193 punct ", ",reported
R3317 T14203 T14202 aux be,expressing
R3318 T14204 T14205 compound TrkC,RNA
R3319 T14212 T14213 mark although,represent
R3320 T14205 T14202 dobj RNA,expressing
R3321 T14213 T14193 advcl represent,reported
R3322 T14214 T14213 nsubj some,represent
R3323 T14215 T14214 prep of,some
R3324 T14312 T14309 nsubj findings,suggest
R3325 T14313 T14314 det a,role
R3326 T14216 T14215 pobj these,of
R3327 T14314 T14309 dobj role,suggest
R3328 T14217 T14214 punct (,some
R3329 T14315 T14314 prep for,role
R3330 T14316 T14315 pobj NT,for
R3331 T14317 T14316 punct -,NT
R3332 T14318 T14316 nummod 3,NT
R3333 T14218 T14219 advmod about,10
R3334 T14319 T14314 prep in,role
R3335 T14320 T14319 pobj initiation,in
R3336 T14219 T14220 nummod 10,%
R3337 T14321 T14320 prep of,initiation
R3338 T14322 T14323 compound muscle,innervation
R3339 T14323 T14321 pobj innervation,of
R3340 T14220 T14214 appos %,some
R3341 T14324 T14320 cc and,initiation
R3342 T14325 T14326 compound spindle,differentiation
R3343 T14326 T14320 conj differentiation,initiation
R3344 T14221 T14214 punct ),some
R3345 T14327 T14326 prep by,differentiation
R3346 T14328 T14329 det the,axons
R3347 T14329 T14327 pobj axons,by
R3348 T14222 T14213 aux may,represent
R3349 T14330 T14329 amod proprioceptive,axons
R3350 T14331 T14309 punct .,suggest
R3351 T14223 T14224 amod cutaneous,innervation
R3352 T14333 T14334 nsubj Patel,examined
R3353 T14224 T14213 dobj innervation,represent
R3354 T14335 T14336 advmod et,al.
R3355 T14336 T14333 advmod al.,Patel
R3356 T14337 T14333 punct (,Patel
R3357 T14225 T14226 punct (,McMahon
R3358 T14338 T14333 npadvmod 2003,Patel
R3359 T14339 T14333 punct ),Patel
R3360 T14340 T14341 npadvmod DiI,labeled
R3361 T14226 T14193 meta McMahon,reported
R3362 T14341 T14343 amod labeled,axons
R3363 T14342 T14341 punct -,labeled
R3364 T14343 T14334 dobj axons,examined
R3365 T14344 T14343 amod central,axons
R3366 T14345 T14343 compound DRG,axons
R3367 T14346 T14343 prep in,axons
R3368 T14227 T14226 nmod et,McMahon
R3369 T14347 T14348 det the,cord
R3370 T14348 T14346 pobj cord,in
R3371 T14349 T14348 amod spinal,cord
R3372 T14228 T14226 nmod al.,McMahon
R3373 T14350 T14348 prep of,cord
R3374 T14351 T14352 nummod three,E17
R3375 T14352 T14350 pobj E17,of
R3376 T14229 T14226 nummod 1994,McMahon
R3377 T14353 T14352 cc and,E17
R3378 T14354 T14355 nummod two,P0
R3379 T14355 T14356 compound P0,cases
R3380 T14230 T14226 punct ),McMahon
R3381 T14356 T14352 conj cases,E17
R3382 T14357 T14334 punct ", ",examined
R3383 T14231 T14193 punct .,reported
R3384 T14358 T14334 cc and,examined
R3385 T14359 T14334 conj report,examined
R3386 T14360 T14361 mark that,stop
R3387 T14233 T14234 advmod Presently,is
R3388 T14361 T14359 ccomp stop,report
R3389 T14362 T14363 amod central,axons
R3390 T14363 T14361 nsubj axons,stop
R3391 T14364 T14363 amod proprioceptive,axons
R3392 T14235 T14234 punct ", ",is
R3393 T14365 T14361 prep in,stop
R3394 T14236 T14234 nsubj it,is
R3395 T14366 T14367 det the,laminae
R3396 T14367 T14365 pobj laminae,in
R3397 T14237 T14234 neg not,is
R3398 T14368 T14367 amod intermediate,laminae
R3399 T14369 T14361 punct ", ",stop
R3400 T14370 T14371 neg never,entering
R3401 T14238 T14234 acomp clear,is
R3402 T14371 T14361 advcl entering,stop
R3403 T14372 T14373 det the,cord
R3404 T14373 T14371 dobj cord,entering
R3405 T14239 T14240 mark whether,made
R3406 T14374 T14373 amod ventral,cord
R3407 T14375 T14334 punct .,examined
R3408 T14240 T14234 advcl made,is
R3409 T14377 T14378 nsubj We,examined
R3410 T14241 T14242 compound TrkC,protein
R3411 T14379 T14378 aux have,examined
R3412 T14380 T14381 nummod nine,cases
R3413 T14242 T14240 nsubjpass protein,made
R3414 T14381 T14378 dobj cases,examined
R3415 T14382 T14383 nmod Bax,KO
R3416 T14383 T14381 compound KO,cases
R3417 T14384 T14382 punct /,Bax
R3418 T14385 T14382 appos NT,Bax
R3419 T14386 T14385 punct -,NT
R3420 T14387 T14385 nummod 3,NT
R3421 T14243 T14240 auxpass is,made
R3422 T14388 T14383 amod double,KO
R3423 T14389 T14378 punct ", ",examined
R3424 T14390 T14378 cc and,examined
R3425 T14244 T14240 advmod also,made
R3426 T14391 T14392 advmod often,gives
R3427 T14392 T14378 conj gives,examined
R3428 T14393 T14394 amod incomplete,labeling
R3429 T14245 T14240 agent by,made
R3430 T14394 T14392 nsubj labeling,gives
R3431 T14395 T14394 compound DiI,labeling
R3432 T14396 T14397 det the,impression
R3433 T14246 T14247 amod cutaneous,afferents
R3434 T14397 T14392 dobj impression,gives
R3435 T14398 T14399 mark that,are
R3436 T14399 T14397 acl are,impression
R3437 T14247 T14245 pobj afferents,by
R3438 T14400 T14399 expl there,are
R3439 T14401 T14402 det no,axons
R3440 T14248 T14240 cc and,made
R3441 T14402 T14399 attr axons,are
R3442 T14403 T14402 acl reaching,axons
R3443 T14404 T14405 det the,cord
R3444 T14249 T14250 mark if,so
R3445 T14405 T14403 dobj cord,reaching
R3446 T14406 T14405 amod ventral,cord
R3447 T14407 T14405 amod spinal,cord
R3448 T14250 T14251 advcl so,expressed
R3449 T14408 T14392 punct .,gives
R3450 T14251 T14240 conj expressed,made
R3451 T14410 T14411 nsubj We,seen
R3452 T14412 T14411 aux have,seen
R3453 T14252 T14251 prep at,expressed
R3454 T14413 T14411 advmod also,seen
R3455 T14414 T14411 dobj cases,seen
R3456 T14415 T14414 amod similar,cases
R3457 T14253 T14254 det what,stage
R3458 T14416 T14415 prep to,similar
R3459 T14417 T14416 pobj theirs,to
R3460 T14254 T14252 pcomp stage,at
R3461 T14255 T14254 prep in,stage
R3462 T14256 T14255 pobj development,in
R3463 T14418 T14419 punct (,4
R3464 T14419 T14414 parataxis 4,cases
R3465 T14420 T14419 nsubj n,4
R3466 T14257 T14258 det this,receptor
R3467 T14421 T14419 punct =,4
R3468 T14422 T14419 punct ),4
R3469 T14423 T14411 punct ", ",seen
R3470 T14424 T14411 cc but,seen
R3471 T14425 T14426 prep at,have
R3472 T14426 T14411 conj have,seen
R3473 T14258 T14251 nsubjpass receptor,expressed
R3474 T14427 T14428 amod higher,magnification
R3475 T14428 T14425 pobj magnification,at
R3476 T14429 T14430 det these,axons
R3477 T14259 T14251 auxpass is,expressed
R3478 T14430 T14426 nsubj axons,have
R3479 T14431 T14426 aux did,have
R3480 T14432 T14426 neg not,have
R3481 T14260 T14251 agent by,expressed
R3482 T14433 T14434 amod terminal,boutons
R3483 T14434 T14426 dobj boutons,have
R3484 T14435 T14426 cc and,have
R3485 T14261 T14262 amod cutaneous,axons
R3486 T14436 T14437 auxpass were,labeled
R3487 T14437 T14426 conj labeled,have
R3488 T14262 T14260 pobj axons,by
R3489 T14438 T14437 neg not,labeled
R3490 T14439 T14437 advmod completely,labeled
R3491 T14440 T14426 punct .,have
R3492 T14263 T14234 punct .,is
R3493 T14442 T14443 advmod However,was
R3494 T14265 T14266 prep Based,think
R3495 T14444 T14443 punct ", ",was
R3496 T14445 T14443 prep with,was
R3497 T14446 T14447 amod complete,fills
R3498 T14447 T14445 pobj fills,with
R3499 T14267 T14265 prep on,Based
R3500 T14448 T14449 punct (,5
R3501 T14449 T14447 parataxis 5,fills
R3502 T14450 T14449 nsubj n,5
R3503 T14268 T14269 det the,evidence
R3504 T14451 T14449 punct =,5
R3505 T14452 T14449 punct ),5
R3506 T14269 T14267 pobj evidence,on
R3507 T14453 T14443 punct ", ",was
R3508 T14270 T14269 amod available,evidence
R3509 T14454 T14443 nsubj it,was
R3510 T14455 T14443 acomp possible,was
R3511 T14271 T14269 acl showing,evidence
R3512 T14456 T14457 aux to,trace
R3513 T14457 T14443 xcomp trace,was
R3514 T14458 T14459 det these,axons
R3515 T14272 T14273 mark that,eliminated
R3516 T14459 T14457 dobj axons,trace
R3517 T14460 T14457 prep into,trace
R3518 T14461 T14462 det the,midline
R3519 T14462 T14460 pobj midline,into
R3520 T14463 T14462 amod ventral,midline
R3521 T14464 T14460 cc and,into
R3522 T14465 T14460 conj across,into
R3523 T14273 T14271 ccomp eliminated,showing
R3524 T14466 T14465 prep to,across
R3525 T14467 T14468 det the,side
R3526 T14274 T14275 det all,neurons
R3527 T14468 T14466 pobj side,to
R3528 T14469 T14468 amod contralateral,side
R3529 T14470 T14457 punct ", ",trace
R3530 T14275 T14273 nsubjpass neurons,eliminated
R3531 T14471 T14457 cc and,trace
R3532 T14472 T14457 conj visualize,trace
R3533 T14473 T14474 amod terminal,boutons
R3534 T14276 T14275 amod proprioceptive,neurons
R3535 T14474 T14472 dobj boutons,visualize
R3536 T14475 T14474 prep at,boutons
R3537 T14476 T14477 poss their,tips
R3538 T14277 T14273 auxpass are,eliminated
R3539 T14477 T14475 pobj tips,at
R3540 T14478 T14479 punct (,see
R3541 T14278 T14273 prep in,eliminated
R3542 T14479 T14472 parataxis see,visualize
R3543 T14480 T14481 compound Figure,3C
R3544 T14481 T14479 dobj 3C,see
R3545 T14279 T14280 npadvmod NT,null
R3546 T14482 T14479 punct ),see
R3547 T14483 T14443 punct .,was
R3548 T14280 T14285 amod null,mice
R3549 T14485 T14486 advmod Previously,reported
R3550 T14281 T14279 punct -,NT
R3551 T14487 T14486 punct ", ",reported
R3552 T14488 T14486 nsubj Arber,reported
R3553 T14489 T14490 advmod et,al.
R3554 T14282 T14279 nummod 3,NT
R3555 T14490 T14488 advmod al.,Arber
R3556 T14491 T14488 punct (,Arber
R3557 T14492 T14488 npadvmod 2000,Arber
R3558 T14283 T14279 cc or,NT
R3559 T14493 T14488 punct ),Arber
R3560 T14494 T14495 mark that,expressed
R3561 T14495 T14486 ccomp expressed,reported
R3562 T14284 T14279 conj TrkC,NT
R3563 T14285 T14278 pobj mice,in
R3564 T14496 T14495 nsubjpass members,expressed
R3565 T14286 T14266 punct ", ",think
R3566 T14497 T14496 prep of,members
R3567 T14498 T14499 det the,family
R3568 T14499 T14497 pobj family,of
R3569 T14287 T14266 nsubj we,think
R3570 T14500 T14499 compound Ets,family
R3571 T14501 T14499 prep of,family
R3572 T14502 T14503 compound transcription,factors
R3573 T14503 T14501 pobj factors,of
R3574 T14504 T14496 punct ", ",members
R3575 T14505 T14496 appos Er81,members
R3576 T14506 T14505 cc and,Er81
R3577 T14288 T14289 mark that,represents
R3578 T14507 T14505 conj Pea3,Er81
R3579 T14508 T14495 punct ", ",expressed
R3580 T14509 T14495 auxpass are,expressed
R3581 T14289 T14266 ccomp represents,think
R3582 T14510 T14495 agent by,expressed
R3583 T14511 T14512 compound DRG,neurons
R3584 T14512 T14510 pobj neurons,by
R3585 T14290 T14291 compound TrkC,staining
R3586 T14513 T14514 advmod as,as
R3587 T14514 T14512 cc as,neurons
R3588 T14291 T14289 nsubj staining,represents
R3589 T14515 T14514 advmod well,as
R3590 T14516 T14517 compound motor,neurons
R3591 T14517 T14512 conj neurons,neurons
R3592 T14292 T14291 prep in,staining
R3593 T14518 T14517 cc and,neurons
R3594 T14519 T14520 poss their,fibers
R3595 T14520 T14517 conj fibers,neurons
R3596 T14293 T14294 det the,nerve
R3597 T14521 T14520 compound target,fibers
R3598 T14522 T14520 compound muscle,fibers
R3600 T14294 T14292 pobj nerve,in
R3601 T14295 T14294 amod tibial,nerve
R3602 T14296 T14289 advmod mostly,represents
R3603 T14525 T14526 nsubj They,found
R3604 T14297 T14298 amod proprioceptive,axons
R3605 T14527 T14528 mark that,were
R3606 T14298 T14289 dobj axons,represents
R3607 T14299 T14298 prep in,axons
R3608 T14528 T14526 ccomp were,found
R3609 T14300 T14301 det the,vicinity
R3610 T14529 T14528 prep in,were
R3611 T14530 T14531 det the,cord
R3612 T14301 T14299 pobj vicinity,in
R3613 T14531 T14529 pobj cord,in
R3614 T14532 T14531 amod spinal,cord
R3615 T14533 T14531 prep of,cord
R3616 T14302 T14301 prep of,vicinity
R3617 T14534 T14535 compound Er81,KO
R3618 T14535 T14536 compound KO,mice
R3619 T14303 T14304 poss their,target
R3620 T14536 T14533 pobj mice,of
R3621 T14537 T14528 punct ", ",were
R3622 T14538 T14539 amod ventral,projections
R3623 T14539 T14528 nsubj projections,were
R3624 T14540 T14539 prep of,projections
R3625 T14541 T14542 amod proprioceptive,axons
R3626 T14542 T14540 pobj axons,of
R3627 T14304 T14302 pobj target,of
R3628 T14543 T14544 advmod mostly,absent
R3629 T14544 T14528 acomp absent,were
R3630 T14545 T14528 punct ", ",were
R3631 T14305 T14304 amod peripheral,target
R3632 T14546 T14528 cc and,were
R3633 T14306 T14266 punct .,think
R3634 T14547 T14548 advmod very,axons
R3635 T14548 T14550 nsubj axons,made
R3636 T14549 T14548 amod few,axons
R3637 T14550 T14528 conj made,were
R3638 T14551 T14550 dobj it,made
R3639 T14552 T14550 prep to,made
R3640 T14308 T14309 advmod Altogether,suggest
R3641 T14553 T14554 det the,cord
R3642 T14554 T14552 pobj cord,to
R3643 T14555 T14554 amod ventral,cord
R3644 T14556 T14526 punct .,found
R3645 T14558 T14559 nsubj Patel,note
R3646 T14310 T14309 punct ", ",suggest
R3647 T14560 T14561 advmod et,al.
R3648 T14561 T14558 advmod al.,Patel
R3649 T14562 T14558 punct (,Patel
R3650 T14563 T14558 npadvmod 2003,Patel
R3651 T14311 T14312 poss our,findings
R3652 T14564 T14558 punct ),Patel
R3653 T14565 T14566 mark that,is
R3654 T14566 T14559 ccomp is,note
R3655 T14567 T14568 det the,phenotype
R3656 T14568 T14566 nsubj phenotype,is
R3657 T14630 T14628 nmod KO,mice
R3658 T14569 T14570 nsubj they,observed
R3659 T14570 T14568 advcl observed,phenotype
R3660 T14571 T14570 prep in,observed
R3661 T14572 T14573 poss their,mice
R3662 T14573 T14571 pobj mice,in
R3663 T14574 T14575 nmod Bax,KO
R3664 T14575 T14573 compound KO,mice
R3665 T14576 T14574 punct /,Bax
R3666 T14577 T14574 appos NT,Bax
R3667 T14631 T14629 punct -,NT
R3668 T14578 T14577 punct -,NT
R3669 T14579 T14577 nummod 3,NT
R3670 T14580 T14575 amod double,KO
R3671 T14632 T14629 nummod 3,NT
R3672 T14581 T14582 advmod quite,similar
R3673 T14582 T14566 acomp similar,is
R3674 T14583 T14582 prep to,similar
R3675 T14584 T14583 pobj that,to
R3676 T14585 T14584 prep of,that
R3677 T14586 T14587 compound Er81,KO
R3678 T14587 T14588 compound KO,mice
R3679 T14588 T14585 pobj mice,of
R3680 T14589 T14559 punct .,note
R3681 T14633 T14630 cc and,KO
R3682 T14591 T14592 nsubj They,provide
R3683 T14593 T14592 dobj evidence,provide
R3684 T14634 T14635 nmod Bax,KO
R3685 T14594 T14595 mark that,induces
R3686 T14595 T14593 acl induces,evidence
R3687 T14635 T14630 conj KO,KO
R3688 T14596 T14595 nsubj NT,induces
R3689 T14597 T14596 punct -,NT
R3690 T14598 T14596 nummod 3,NT
R3691 T14636 T14634 punct /,Bax
R3692 T14599 T14600 compound Er81,expression
R3693 T14600 T14595 dobj expression,induces
R3694 T14601 T14595 prep in,induces
R3695 T14637 T14634 appos NT,Bax
R3696 T14602 T14603 compound DRG,explants
R3697 T14603 T14601 pobj explants,in
R3698 T14604 T14605 advmod in,vitro
R3699 T14638 T14637 punct -,NT
R3700 T14605 T14595 advmod vitro,induces
R3701 T14606 T14592 punct .,provide
R3702 T14639 T14637 nummod 3,NT
R3703 T14608 T14609 nsubj Patel,report
R3704 T14610 T14611 advmod et,al.
R3705 T14611 T14608 advmod al.,Patel
R3707 T14612 T14608 punct (,Patel
R3708 T14613 T14608 npadvmod 2003,Patel
R3709 T14614 T14608 punct ),Patel
R3710 T14641 T14609 punct ", ",report
R3711 T14615 T14616 mark that,diminished
R3712 T14616 T14609 ccomp diminished,report
R3713 T14617 T14618 compound Er81,expression
R3714 T14642 T14643 mark while,shows
R3715 T14618 T14616 nsubj expression,diminished
R3716 T14619 T14618 compound mRNA,expression
R3717 T14620 T14616 aux is,diminished
R3718 T14643 T14609 advcl shows,report
R3719 T14621 T14616 punct (,diminished
R3720 T14622 T14616 cc but,diminished
R3721 T14623 T14624 neg not,abolished
R3722 T14644 T14645 poss their,immunohistochemistry
R3723 T14624 T14616 conj abolished,diminished
R3724 T14645 T14643 nsubj immunohistochemistry,shows
R3725 T14625 T14616 punct ),diminished
R3726 T14626 T14616 prep in,diminished
R3727 T14627 T14628 preconj both,mice
R3728 T14628 T14626 pobj mice,in
R3729 T14629 T14630 nmod NT,KO
R3730 T14646 T14647 advmod much,less
R3731 T14647 T14648 amod less,expression
R3732 T14648 T14643 dobj expression,shows
R3733 T14649 T14648 compound protein,expression
R3734 T14736 T14734 pobj cord,to
R3735 T14737 T14736 amod ventral,cord
R3736 T14650 T14643 prep in,shows
R3737 T14738 T14736 amod spinal,cord
R3738 T14739 T14727 cc and,find
R3739 T14740 T14727 conj target,find
R3740 T14651 T14652 det the,mice
R3741 T14741 T14740 advmod properly,target
R3742 T14742 T14740 prep to,target
R3743 T14743 T14744 det the,neurons
R3744 T14652 T14650 pobj mice,in
R3745 T14744 T14742 pobj neurons,to
R3746 T14745 T14744 compound motor,neurons
R3747 T14653 T14654 amod double,KO
R3748 T14746 T14747 punct (,Arber
R3749 T14747 T14725 meta Arber,note
R3750 T14748 T14747 nmod et,Arber
R3751 T14654 T14652 compound KO,mice
R3752 T14749 T14747 nmod al.,Arber
R3753 T14750 T14747 nummod 2000,Arber
R3754 T14751 T14747 punct ),Arber
R3755 T14655 T14609 punct .,report
R3756 T14752 T14707 punct .,is
R3757 T14754 T14755 nsubj Patel,present
R3758 T14657 T14658 nsubj It,is
R3759 T14756 T14757 advmod et,al.
R3760 T14757 T14754 advmod al.,Patel
R3761 T14758 T14754 punct (,Patel
R3762 T14759 T14754 npadvmod 2003,Patel
R3763 T14659 T14660 advmod highly,possible
R3764 T14760 T14754 punct ),Patel
R3765 T14761 T14755 advmod also,present
R3766 T14762 T14755 dobj observations,present
R3767 T14660 T14658 acomp possible,is
R3768 T14763 T14762 prep from,observations
R3769 T14764 T14765 compound islet2DTA,mice
R3770 T14765 T14763 pobj mice,from
R3771 T14661 T14662 mark that,express
R3772 T14766 T14765 punct ", ",mice
R3773 T14767 T14768 dep which,lack
R3774 T14768 T14765 relcl lack,mice
R3775 T14662 T14658 advcl express,is
R3776 T14769 T14770 det a,portion
R3777 T14770 T14768 dobj portion,lack
R3778 T14771 T14770 amod significant,portion
R3779 T14772 T14770 prep of,portion
R3780 T14773 T14774 det the,neurons
R3781 T14774 T14772 pobj neurons,of
R3782 T14663 T14664 det a,number
R3783 T14775 T14774 compound motor,neurons
R3784 T14776 T14774 prep in,neurons
R3785 T14777 T14778 det the,cord
R3786 T14664 T14662 nsubj number,express
R3787 T14778 T14776 pobj cord,in
R3788 T14779 T14778 amod ventral,cord
R3789 T14780 T14755 punct .,present
R3790 T14665 T14664 amod small,number
R3791 T14782 T14783 prep In,shows
R3792 T14666 T14665 cc but,small
R3793 T14784 T14785 det these,mice
R3794 T14785 T14782 pobj mice,In
R3795 T14667 T14665 conj considerable,small
R3796 T14786 T14787 compound PV,immunostaining
R3797 T14787 T14783 nsubj immunostaining,shows
R3798 T14788 T14783 dobj axons,shows
R3799 T14668 T14664 prep of,number
R3800 T14789 T14788 prep in,axons
R3801 T14790 T14791 det the,horns
R3802 T14791 T14789 pobj horns,in
R3803 T14669 T14670 compound DRG,cells
R3804 T14792 T14791 amod ventral,horns
R3805 T14793 T14783 punct .,shows
R3806 T14670 T14668 pobj cells,of
R3807 T14795 T14796 nsubj Patel,argue
R3808 T14671 T14672 det the,factor
R3809 T14672 T14662 dobj factor,express
R3810 T14797 T14798 advmod et,al.
R3811 T14798 T14795 advmod al.,Patel
R3812 T14673 T14672 compound transcription,factor
R3813 T14799 T14800 mark that,be
R3814 T14800 T14796 ccomp be,argue
R3815 T14674 T14672 appos Er81,factor
R3816 T14801 T14802 mark since,are
R3817 T14802 T14800 advcl are,be
R3818 T14803 T14804 compound motor,neurons
R3819 T14675 T14662 cc and,express
R3820 T14804 T14802 nsubj neurons,are
R3821 T14805 T14802 acomp absent,are
R3822 T14806 T14802 prep in,are
R3823 T14676 T14677 mark that,grow
R3824 T14807 T14808 det these,mice
R3825 T14808 T14806 pobj mice,in
R3826 T14677 T14662 conj grow,express
R3827 T14809 T14800 punct ", ",be
R3828 T14810 T14800 nsubj NT,be
R3829 T14811 T14810 punct -,NT
R3830 T14812 T14810 nummod 3,NT
R3831 T14813 T14810 acl secreted,NT
R3832 T14814 T14813 prep by,secreted
R3833 T14678 T14679 poss their,axons
R3834 T14815 T14814 pobj them,by
R3835 T14816 T14800 aux could,be
R3836 T14817 T14800 neg not,be
R3837 T14679 T14677 nsubj axons,grow
R3838 T14818 T14819 det a,signal
R3839 T14819 T14800 attr signal,be
R3840 T14820 T14821 mark for,enter
R3841 T14680 T14677 prep beyond,grow
R3842 T14821 T14819 advcl enter,signal
R3843 T14822 T14823 amod proprioceptive,axons
R3844 T14823 T14821 nsubj axons,enter
R3845 T14681 T14682 det the,levels
R3846 T14824 T14821 aux to,enter
R3847 T14825 T14826 det the,columns
R3848 T14682 T14680 pobj levels,beyond
R3849 T14826 T14821 dobj columns,enter
R3850 T14827 T14826 amod lateral,columns
R3851 T14828 T14826 compound motor,columns
R3852 T14683 T14682 amod intermediate,levels
R3853 T14829 T14796 punct .,argue
R3854 T14684 T14682 prep of,levels
R3855 T14831 T14832 advmod However,is
R3856 T14833 T14832 punct ", ",is
R3857 T14685 T14686 det the,cord
R3858 T14834 T14832 expl there,is
R3859 T14835 T14836 det no,evidence
R3860 T14836 T14832 attr evidence,is
R3861 T14686 T14684 pobj cord,of
R3862 T14837 T14836 acl showing,evidence
R3863 T14838 T14839 mark that,is
R3864 T14687 T14686 amod spinal,cord
R3865 T14839 T14837 ccomp is,showing
R3866 T14840 T14841 nmod NT,mRNA
R3867 T14841 T14839 nsubj mRNA,is
R3868 T14688 T14677 prep in,grow
R3869 T14689 T14690 nmod Bax,KO
R3870 T14690 T14696 compound KO,mice
R3871 T14842 T14840 punct -,NT
R3872 T14843 T14840 nummod 3,NT
R3873 T14844 T14841 cc or,mRNA
R3874 T14691 T14689 punct /,Bax
R3875 T14845 T14841 conj protein,mRNA
R3876 T14846 T14845 acl expressed,protein
R3877 T14692 T14689 appos NT,Bax
R3878 T14847 T14846 prep in,expressed
R3879 T14848 T14849 det the,cord
R3880 T14849 T14847 pobj cord,in
R3881 T14693 T14692 punct -,NT
R3882 T14850 T14849 amod ventral,cord
R3883 T14851 T14849 amod spinal,cord
R3884 T14852 T14839 advmod exclusively,is
R3885 T14853 T14839 prep from,is
R3886 T14854 T14855 compound motor,neurons
R3887 T14694 T14692 nummod 3,NT
R3888 T14855 T14853 pobj neurons,from
R3889 T14856 T14832 punct ", ",is
R3890 T14857 T14832 cc and,is
R3891 T14695 T14690 amod double,KO
R3892 T14858 T14859 expl there,are
R3893 T14859 T14832 conj are,is
R3894 T14696 T14688 pobj mice,in
R3895 T14860 T14861 det no,data
R3896 T14861 T14859 attr data,are
R3897 T14862 T14861 amod available,data
R3898 T14697 T14658 punct .,is
R3899 T14863 T14861 acl indicating,data
R3900 T14864 T14865 mark that,abolished
R3901 T14699 T14700 mark While,is
R3902 T14865 T14863 ccomp abolished,indicating
R3903 T14700 T14707 advcl is,is
R3904 T14866 T14865 prep in,abolished
R3905 T14867 T14868 compound islet2DTA,mice
R3906 T14868 T14866 pobj mice,in
R3907 T14701 T14702 det the,phenotype
R3908 T14869 T14865 punct ", ",abolished
R3909 T14870 T14871 nmod NT,expression
R3910 T14871 T14865 nsubjpass expression,abolished
R3911 T14702 T14700 nsubj phenotype,is
R3912 T14872 T14870 punct -,NT
R3913 T14873 T14870 nummod 3,NT
R3914 T14703 T14702 prep of,phenotype
R3915 T14874 T14871 prep in,expression
R3916 T14875 T14876 det the,cord
R3917 T14876 T14874 pobj cord,in
R3918 T14704 T14705 compound Er81,KO
R3919 T14877 T14876 amod ventral,cord
R3920 T14878 T14876 amod spinal,cord
R3921 T14879 T14865 auxpass is,abolished
R3922 T14705 T14706 compound KO,mice
R3923 T14880 T14881 punct (,Yang
R3924 T14881 T14832 meta Yang,is
R3925 T14706 T14703 pobj mice,of
R3926 T14708 T14709 advmod quite,dramatic
R3927 T14882 T14881 nmod et,Yang
R3928 T14883 T14881 nmod al.,Yang
R3929 T14884 T14881 nummod 2001,Yang
R3930 T14709 T14700 attr dramatic,is
R3931 T14885 T14881 punct ;,Yang
R3932 T14886 T14881 nmod Pun,Yang
R3933 T14887 T14881 nmod et,Yang
R3934 T14888 T14881 nmod al.,Yang
R3935 T14889 T14881 nummod 2002,Yang
R3936 T14710 T14700 punct ", ",is
R3937 T14890 T14881 punct ),Yang
R3938 T14891 T14832 punct .,is
R3939 T14711 T14700 cc and,is
R3940 T14893 T14894 nsubj Studies,reported
R3941 T14895 T14893 prep in,Studies
R3942 T14712 T14713 amod most,axons
R3943 T14896 T14897 amod embryonic,mice
R3944 T14897 T14895 pobj mice,in
R3945 T14713 T14715 nsubj axons,stop
R3946 T14898 T14899 nmod NT,mRNA
R3947 T14899 T14894 dobj mRNA,reported
R3948 T14900 T14898 punct -,NT
R3949 T14714 T14713 amod proprioceptive,axons
R3950 T14901 T14898 nummod 3,NT
R3951 T14902 T14894 prep in,reported
R3952 T14715 T14700 conj stop,is
R3953 T14903 T14904 det the,horns
R3954 T14904 T14902 pobj horns,in
R3955 T14905 T14904 amod ventral,horns
R3956 T14716 T14715 prep within,stop
R3957 T14906 T14904 prep of,horns
R3958 T14907 T14908 det the,cord
R3959 T14908 T14906 pobj cord,of
R3960 T14717 T14718 det the,cord
R3961 T14909 T14908 amod spinal,cord
R3962 T14910 T14894 punct ", ",reported
R3963 T14911 T14894 cc but,reported
R3964 T14718 T14716 pobj cord,within
R3965 T14912 T14913 nsubj it,is
R3966 T14913 T14894 conj is,reported
R3967 T14719 T14718 amod intermediate,cord
R3971 T14720 T14718 amod spinal,cord
R3972 T14917 T14913 ccomp expressed,is
R3973 T14918 T14919 preconj both,mRNA
R3974 T14919 T14917 nsubjpass mRNA,expressed
R3975 T14721 T14707 punct ", ",is
R3976 T14920 T14919 cc and,mRNA
R3977 T14921 T14919 conj protein,mRNA
R3978 T14722 T14707 nsubj it,is
R3979 T14922 T14917 auxpass are,expressed
R3980 T14923 T14917 advmod solely,expressed
R3981 T14924 T14917 agent by,expressed
R3982 T14723 T14707 acomp important,is
R3983 T14925 T14926 compound motor,neurons
R3984 T14926 T14924 pobj neurons,by
R3985 T14927 T14913 punct .,is
R3986 T14929 T14930 prep In,express
R3987 T14931 T14932 det the,cord
R3988 T14724 T14725 aux to,note
R3989 T14932 T14929 pobj cord,In
R3990 T14933 T14932 amod adult,cord
R3991 T14934 T14932 amod spinal,cord
R3992 T14725 T14707 xcomp note,is
R3993 T14935 T14930 punct ", ",express
R3994 T14936 T14937 mark while,express
R3995 T14937 T14930 advcl express,express
R3996 T14726 T14727 mark that,find
R3997 T14938 T14939 compound motor,neurons
R3998 T14939 T14937 nsubj neurons,express
R3999 T14940 T14941 amod high,levels
R4000 T14727 T14725 ccomp find,note
R4001 T14941 T14937 dobj levels,express
R4002 T14942 T14941 prep of,levels
R4003 T14728 T14729 det a,axons
R4004 T14943 T14942 pobj NT,of
R4005 T14944 T14943 punct -,NT
R4006 T14945 T14943 nummod 3,NT
R4007 T14729 T14727 nsubj axons,find
R4008 T14946 T14930 punct ", ",express
R4009 T14947 T14948 amod other,cells
R4010 T14730 T14729 amod few,axons
R4011 T14731 T14727 advmod still,find
R4012 T14732 T14733 poss their,way
R4013 T14948 T14930 nsubj cells,express
R4014 T14949 T14948 punct ", ",cells
R4015 T14950 T14948 prep including,cells
R4016 T14733 T14727 dobj way,find
R4017 T14951 T14950 pobj glia,including
R4018 T14952 T14930 punct ", ",express
R4019 T14734 T14727 prep to,find
R4020 T14953 T14930 advmod also,express
R4021 T14954 T14930 dobj it,express
R4022 T14955 T14956 punct (,Zhou
R4023 T14735 T14736 det the,cord
R4024 T14956 T14930 meta Zhou,express
R4025 T14957 T14956 cc and,Zhou
R4026 T15054 T15050 pobj null,in
R4027 T14958 T14956 conj Rush,Zhou
R4028 T14959 T14958 nummod 1994,Rush
R4029 T14960 T14958 punct ;,Rush
R4030 T14961 T14958 conj Dreyfus,Rush
R4031 T14962 T14961 nmod et,Dreyfus
R4032 T15055 T15050 cc and,in
R4033 T14963 T14961 nmod al.,Dreyfus
R4034 T15056 T15050 conj in,in
R4035 T15057 T15058 npadvmod p75,null
R4036 T14964 T14961 nummod 1999,Dreyfus
R4037 T14965 T14961 punct ;,Dreyfus
R4038 T14966 T14961 conj Buck,Dreyfus
R4039 T14967 T14966 nmod et,Buck
R4040 T14968 T14966 nmod al.,Buck
R4041 T14969 T14966 nummod 2000,Buck
R4042 T14970 T14966 punct ),Buck
R4043 T15058 T15056 pobj null,in
R4044 T14971 T14930 punct .,express
R4045 T14973 T14974 poss Our,results
R4046 T15059 T15060 compound DRG,explants
R4047 T14974 T14976 nsubj results,argue
R4048 T14975 T14974 amod present,results
R4049 T15060 T15056 pobj explants,in
R4050 T14977 T14974 punct ", ",results
R4051 T14978 T14974 cc along,results
R4052 T15061 T15050 punct ", ",in
R4053 T14979 T14978 dep with,along
R4054 T14980 T14974 conj those,results
R4055 T15062 T15050 cc and,in
R4056 T14981 T14980 prep from,those
R4057 T14982 T14983 amod transgenic,mice
R4058 T14983 T14981 pobj mice,from
R4059 T15063 T15050 conj in,in
R4060 T14984 T14983 prep with,mice
R4061 T14985 T14986 nmod NT,over-expression
R4062 T14986 T14984 pobj over-expression,with
R4063 T15064 T15065 det the,absence
R4064 T14987 T14985 punct -,NT
R4065 T14988 T14985 nummod 3,NT
R4066 T14989 T14986 prep in,over-expression
R4067 T15065 T15063 pobj absence,in
R4068 T14990 T14991 amod ectopic,regions
R4069 T14991 T14989 pobj regions,in
R4070 T15066 T15065 prep of,absence
R4071 T14992 T14991 prep of,regions
R4072 T14993 T14994 det the,cord
R4073 T14994 T14992 pobj cord,of
R4074 T15067 T15068 det any,neurotrophins
R4075 T14995 T14994 amod spinal,cord
R4076 T14996 T14997 punct (,Ringstedt
R4077 T14997 T14980 meta Ringstedt,those
R4078 T15068 T15066 pobj neurotrophins,of
R4079 T14998 T14997 nmod et,Ringstedt
R4080 T14999 T14997 nmod al.,Ringstedt
R4081 T15069 T15068 amod other,neurotrophins
R4082 T15000 T14997 nummod 1997,Ringstedt
R4083 T15001 T14997 punct ),Ringstedt
R4084 T15002 T14976 punct ", ",argue
R4085 T15070 T15068 cc or,neurotrophins
R4086 T15003 T14976 prep for,argue
R4087 T15004 T15005 det a,role
R4088 T15005 T15003 pobj role,for
R4089 T15071 T15072 npadvmod target,derived
R4090 T15006 T15005 prep of,role
R4091 T15007 T15006 pobj NT,of
R4092 T15008 T15007 punct -,NT
R4093 T15009 T15007 nummod 3,NT
R4094 T15010 T15005 prep in,role
R4095 T15011 T15012 compound chemoattractant,guidance
R4096 T15072 T15074 amod derived,molecules
R4097 T15012 T15010 pobj guidance,in
R4098 T15013 T15012 compound axon,guidance
R4099 T15014 T15012 prep of,guidance
R4100 T15073 T15072 punct -,derived
R4101 T15015 T15016 amod proprioceptive,axons
R4102 T15016 T15014 pobj axons,of
R4103 T15017 T15012 prep in,guidance
R4104 T15074 T15068 conj molecules,neurotrophins
R4105 T15018 T15019 det the,cord
R4106 T15019 T15017 pobj cord,in
R4107 T15075 T15076 compound axon,guidance
R4108 T15020 T15019 amod spinal,cord
R4109 T15021 T14976 punct .,argue
R4110 T15076 T15074 compound guidance,molecules
R4111 T15023 T15024 advmod Finally,see
R4112 T15025 T15024 punct ", ",see
R4113 T15077 T15048 punct .,seen
R4114 T15026 T15024 prep in,see
R4115 T15027 T15028 compound culture,assays
R4116 T15028 T15026 pobj assays,in
R4117 T15079 T15080 advmod Furthermore,appear
R4118 T15029 T15024 punct ", ",see
R4119 T15030 T15024 nsubj we,see
R4120 T15031 T15032 det a,chemoattraction
R4121 T15032 T15024 dobj chemoattraction,see
R4122 T15081 T15080 punct ", ",appear
R4123 T15033 T15032 amod strong,chemoattraction
R4124 T15034 T15032 prep of,chemoattraction
R4125 T15035 T15036 compound DRG,neurons
R4126 T15036 T15034 pobj neurons,of
R4127 T15082 T15083 advmod in,vitro
R4128 T15037 T15032 prep to,chemoattraction
R4129 T15038 T15039 amod localized,sources
R4130 T15039 T15037 pobj sources,to
R4131 T15083 T15080 advmod vitro,appear
R4132 T15040 T15039 prep of,sources
R4133 T15041 T15040 pobj NT,of
R4134 T15084 T15080 punct ", ",appear
R4135 T15042 T15041 punct -,NT
R4136 T15043 T15041 nummod 3,NT
R4137 T15044 T15024 punct .,see
R4138 T15085 T15086 amod sensory,axon
R4139 T15046 T15047 det This,response
R4140 T15047 T15048 nsubjpass response,seen
R4141 T15086 T15087 compound axon,response
R4142 T15049 T15048 auxpass is,seen
R4143 T15050 T15048 prep in,seen
R4144 T15087 T15080 nsubj response,appear
R4145 T15051 T15052 nmod WT,Bax
R4146 T15052 T15054 npadvmod Bax,null
R4147 T15053 T15052 punct ", ",Bax
R4148 T15088 T15087 prep to,response
R4149 T15089 T15088 pobj NT,to
R4150 T15090 T15089 punct -,NT
R4151 T15160 T15159 amod primary,axons
R4152 T15091 T15089 nummod 3,NT
R4153 T15161 T15159 amod sensory,axons
R4154 T15162 T15147 aux have,indicated
R4155 T15092 T15080 aux does,appear
R4156 T15163 T15164 mark that,attract
R4157 T15164 T15147 ccomp attract,indicated
R4158 T15093 T15080 neg not,appear
R4159 T15165 T15166 det this,neurotrophin
R4160 T15166 T15164 nsubj neurotrophin,attract
R4161 T15167 T15164 aux can,attract
R4162 T15168 T15164 cc and,attract
R4163 T15094 T15095 aux to,be
R4164 T15169 T15164 conj induce,attract
R4165 T15170 T15171 amod axonal,branching
R4166 T15095 T15080 xcomp be,appear
R4167 T15171 T15169 dobj branching,induce
R4168 T15172 T15173 punct (,Ulupınar
R4169 T15173 T15147 meta Ulupınar,indicated
R4170 T15096 T15097 npadvmod dose,dependent
R4171 T15174 T15173 nmod et,Ulupınar
R4172 T15175 T15173 nmod al.,Ulupınar
R4173 T15176 T15173 nummod 2000,Ulupınar
R4174 T15097 T15095 acomp dependent,be
R4175 T15177 T15173 punct ;,Ulupınar
R4176 T15178 T15173 conj Özdinler,Ulupınar
R4177 T15179 T15178 cc and,Özdinler
R4178 T15098 T15097 punct -,dependent
R4179 T15180 T15178 conj Erzurumlu,Özdinler
R4180 T15181 T15180 nummod 2001,Erzurumlu
R4181 T15182 T15180 punct ", ",Erzurumlu
R4182 T15099 T15100 punct (,Ringstedt
R4183 T15183 T15180 conj Özdinler,Erzurumlu
R4184 T15184 T15183 nmod et,Özdinler
R4185 T15185 T15183 nmod al.,Özdinler
R4186 T15100 T15080 meta Ringstedt,appear
R4187 T15186 T15183 nummod 2004,Özdinler
R4188 T15187 T15183 punct ),Özdinler
R4189 T15188 T15147 punct .,indicated
R4190 T15101 T15100 nmod et,Ringstedt
R4191 T15190 T15191 prep Along,implicated
R4192 T15102 T15100 nmod al.,Ringstedt
R4193 T15192 T15193 det the,pathway
R4194 T15193 T15190 pobj pathway,Along
R4195 T15194 T15193 amod monosynaptic,pathway
R4196 T15195 T15196 compound stretch,reflex
R4197 T15196 T15193 compound reflex,pathway
R4198 T15197 T15191 punct ", ",implicated
R4199 T15103 T15100 nummod 1997,Ringstedt
R4200 T15198 T15199 advmod only,Wnt
R4201 T15199 T15191 nsubjpass Wnt,implicated
R4202 T15200 T15199 punct -,Wnt
R4203 T15104 T15100 punct ;,Ringstedt
R4204 T15201 T15199 nummod 3,Wnt
R4205 T15202 T15191 aux has,implicated
R4206 T15203 T15191 auxpass been,implicated
R4207 T15105 T15100 nmod Tucker,Ringstedt
R4208 T15204 T15191 prep as,implicated
R4209 T15205 T15206 det an,factor
R4210 T15206 T15204 pobj factor,as
R4211 T15106 T15100 nmod et,Ringstedt
R4212 T15207 T15208 compound axon,arborization
R4213 T15208 T15206 compound arborization,factor
R4214 T15209 T15206 prep in,factor
R4215 T15107 T15100 nmod al.,Ringstedt
R4216 T15210 T15211 det the,cord
R4217 T15211 T15209 pobj cord,in
R4218 T15108 T15100 nummod 2001,Ringstedt
R4219 T15212 T15211 amod spinal,cord
R4220 T15213 T15214 punct (,Krylova
R4221 T15214 T15191 meta Krylova,implicated
R4222 T15109 T15100 punct ),Ringstedt
R4223 T15215 T15214 nmod et,Krylova
R4224 T15216 T15214 nmod al.,Krylova
R4225 T15217 T15214 nummod 2002,Krylova
R4226 T15110 T15080 punct .,appear
R4227 T15218 T15214 punct ),Krylova
R4228 T15219 T15191 punct .,implicated
R4229 T15112 T15113 nsubj NT,is
R4230 T15221 T15222 det Another,molecule
R4231 T15114 T15112 punct -,NT
R4232 T15222 T15223 nsubj molecule,is
R4233 T15115 T15112 nummod 3,NT
R4234 T15224 T15222 punct ", ",molecule
R4235 T15225 T15222 appos Slit2,molecule
R4236 T15226 T15222 punct ", ",molecule
R4237 T15116 T15113 acomp capable,is
R4238 T15227 T15222 acl expressed,molecule
R4239 T15228 T15227 prep in,expressed
R4240 T15229 T15230 det the,midline
R4241 T15117 T15116 prep of,capable
R4242 T15230 T15228 pobj midline,in
R4243 T15231 T15228 cc and,in
R4244 T15118 T15117 pcomp attracting,of
R4245 T15232 T15228 conj by,in
R4246 T15233 T15234 compound motor,neurons
R4247 T15234 T15232 pobj neurons,by
R4248 T15235 T15236 punct (,Wang
R4249 T15236 T15227 meta Wang,expressed
R4250 T15237 T15236 nmod et,Wang
R4251 T15238 T15236 nmod al.,Wang
R4252 T15119 T15118 dobj axons,attracting
R4253 T15239 T15236 nummod 1999,Wang
R4254 T15240 T15236 punct ),Wang
R4255 T15241 T15223 acomp capable,is
R4256 T15120 T15118 prep along,attracting
R4257 T15242 T15241 prep of,capable
R4258 T15243 T15242 pcomp inducing,of
R4259 T15244 T15245 amod axonal,branching
R4260 T15245 T15243 dobj branching,inducing
R4261 T15121 T15120 pobj distances,along
R4262 T15246 T15247 punct (,Nguyen
R4263 T15247 T15223 meta Nguyen,is
R4264 T15248 T15247 nmod Ba,Nguyen
R4265 T15122 T15121 prep of,distances
R4266 T15249 T15247 punct -,Nguyen
R4267 T15250 T15247 nmod Charvet,Nguyen
R4268 T15123 T15124 quantmod up,1
R4269 T15251 T15247 nmod et,Nguyen
R4270 T15252 T15247 nmod al.,Nguyen
R4271 T15253 T15247 nummod 2001,Nguyen
R4272 T15124 T15126 nummod 1,mm
R4273 T15254 T15247 punct ;,Nguyen
R4274 T15255 T15247 conj Özdinler,Nguyen
R4275 T15256 T15255 cc and,Özdinler
R4276 T15125 T15124 quantmod to,1
R4277 T15257 T15255 conj Erzurumlu,Özdinler
R4278 T15258 T15257 nummod 2002,Erzurumlu
R4279 T15259 T15257 punct ),Erzurumlu
R4280 T15126 T15122 pobj mm,of
R4281 T15260 T15223 punct .,is
R4282 T15127 T15118 prep in,attracting
R4283 T15262 T15263 compound DRG,neurons
R4284 T15263 T15264 nsubj neurons,express
R4285 T15265 T15266 compound Robo,receptors
R4286 T15128 T15129 compound collagen,matrix
R4287 T15129 T15127 pobj matrix,in
R4288 T15130 T15129 compound gel,matrix
R4289 T15131 T15113 punct ", ",is
R4290 T15266 T15264 dobj receptors,express
R4291 T15267 T15266 punct ", ",receptors
R4292 T15268 T15269 dep which,bind
R4293 T15269 T15266 relcl bind,receptors
R4294 T15132 T15113 advcl covering,is
R4295 T15133 T15134 det the,range
R4296 T15134 T15132 dobj range,covering
R4297 T15135 T15134 amod physiological,range
R4298 T15270 T15269 prep to,bind
R4299 T15271 T15270 pobj Slits,to
R4300 T15272 T15264 punct ", ",express
R4301 T15273 T15264 cc and,express
R4302 T15274 T15275 amod proprioceptive,axons
R4303 T15136 T15137 nsubj it,needs
R4304 T15275 T15276 nsubj axons,are
R4305 T15276 T15264 conj are,express
R4306 T15277 T15276 advmod therefore,are
R4307 T15137 T15134 advcl needs,range
R4308 T15278 T15276 acomp capable,are
R4309 T15279 T15278 prep of,capable
R4310 T15280 T15279 pcomp responding,of
R4311 T15138 T15139 aux to,attract
R4312 T15281 T15280 prep to,responding
R4313 T15282 T15283 compound Slit,signals
R4314 T15283 T15281 pobj signals,to
R4315 T15284 T15285 punct (,Wang
R4316 T15139 T15137 advcl attract,needs
R4317 T15285 T15276 meta Wang,are
R4318 T15286 T15285 nmod et,Wang
R4319 T15140 T15139 dobj axons,attract
R4320 T15287 T15285 nmod al.,Wang
R4321 T15288 T15285 nummod 1999,Wang
R4322 T15289 T15285 punct ),Wang
R4323 T15290 T15276 punct .,are
R4324 T15141 T15139 prep during,attract
R4326 T15142 T15141 pobj development,during
R4327 T15294 T15293 aux does,cause
R4328 T15295 T15293 neg not,cause
R4329 T15296 T15293 dobj repulsion,cause
R4330 T15143 T15113 punct .,is
R4331 T15297 T15296 prep of,repulsion
R4332 T15298 T15299 npadvmod NT,responsive
R4333 T15299 T15303 amod responsive,axons
R4334 T15145 T15146 amod Previous,studies
R4335 T15300 T15298 punct -,NT
R4336 T15301 T15298 nummod 3,NT
R4337 T15302 T15299 punct -,responsive
R4338 T15303 T15297 pobj axons,of
R4339 T15146 T15147 nsubj studies,indicated
R4340 T15304 T15303 compound DRG,axons
R4341 T15305 T15306 advmod in,vitro
R4342 T15148 T15146 prep with,studies
R4343 T15306 T15293 advmod vitro,cause
R4344 T15307 T15308 punct (,Nguyen
R4345 T15149 T15150 amod exogenous,applications
R4346 T15308 T15293 meta Nguyen,cause
R4347 T15150 T15148 pobj applications,with
R4348 T15309 T15308 nmod Ba,Nguyen
R4349 T15310 T15308 punct -,Nguyen
R4350 T15311 T15308 nmod Charvet,Nguyen
R4351 T15312 T15308 nmod et,Nguyen
R4352 T15313 T15308 nmod al.,Nguyen
R4353 T15314 T15308 nummod 2001,Nguyen
R4354 T15151 T15149 cc or,exogenous
R4355 T15315 T15308 punct ),Nguyen
R4356 T15316 T15293 punct ", ",cause
R4357 T15152 T15149 conj local,exogenous
R4358 T15317 T15293 cc but,cause
R4359 T15318 T15293 conj causes,cause
R4360 T15153 T15150 prep of,applications
R4361 T15319 T15320 amod ectopic,branching
R4362 T15320 T15318 dobj branching,causes
R4363 T15321 T15320 cc and,branching
R4364 T15154 T15153 pobj NT,of
R4365 T15322 T15320 conj arborization,branching
R4366 T15323 T15320 prep of,branching
R4367 T15324 T15325 amod trigeminal,axons
R4368 T15155 T15154 punct -,NT
R4369 T15325 T15323 pobj axons,of
R4370 T15326 T15318 prep in,causes
R4371 T15327 T15328 det the,brainstem
R4372 T15156 T15154 nummod 3,NT
R4373 T15328 T15326 pobj brainstem,in
R4374 T15329 T15330 punct (,Özdinler
R4375 T15157 T15150 prep to,applications
R4376 T15330 T15318 meta Özdinler,causes
R4377 T15331 T15330 cc and,Özdinler
R4378 T15332 T15330 conj Erzurumlu,Özdinler
R4379 T15158 T15159 amod developing,axons
R4380 T15333 T15332 nummod 2002,Erzurumlu
R4381 T15334 T15332 punct ),Erzurumlu
R4382 T15159 T15157 pobj axons,to
R4383 T15335 T15293 punct .,cause
R4384 T15337 T15338 advmod Thus,involved
R4385 T15372 T15373 nmod Bax,KO
R4386 T15339 T15338 punct ", ",involved
R4387 T15340 T15338 nsubjpass Slit2,involved
R4388 T15341 T15338 aux might,involved
R4389 T15373 T15378 compound KO,mice
R4390 T15342 T15338 advmod also,involved
R4391 T15343 T15338 auxpass be,involved
R4392 T15344 T15338 prep in,involved
R4393 T15374 T15372 punct /,Bax
R4394 T15345 T15346 amod terminal,branching
R4395 T15346 T15344 pobj branching,in
R4396 T15347 T15346 prep of,branching
R4397 T15375 T15372 appos NT,Bax
R4398 T15348 T15349 amod propioceptive,axons
R4399 T15349 T15347 pobj axons,of
R4400 T15350 T15346 prep in,branching
R4401 T15376 T15375 punct -,NT
R4402 T15351 T15352 det the,cord
R4403 T15352 T15350 pobj cord,in
R4404 T15353 T15352 amod ventral,cord
R4405 T15354 T15344 cc and,in
R4406 T15355 T15344 conj in,in
R4407 T15356 T15357 det the,branching
R4408 T15377 T15375 nummod 3,NT
R4409 T15357 T15355 pobj branching,in
R4410 T15358 T15357 compound midline,branching
R4411 T15359 T15357 acl observed,branching
R4412 T15378 T15371 pobj mice,in
R4413 T15360 T15359 prep in,observed
R4414 T15361 T15362 poss our,KOs
R4415 T15362 T15360 pobj KOs,in
R4416 T15379 T15380 mark that,be
R4417 T15363 T15362 amod double,KOs
R4418 T15364 T15338 punct .,involved
R4419 T15380 T15367 ccomp be,suggests
R4420 T15366 T15367 nsubj Lack,suggests
R4421 T15381 T15382 compound PV,expression
R4422 T15368 T15366 prep of,Lack
R4423 T15369 T15370 compound PV,expression
R4424 T15370 T15368 pobj expression,of
R4425 T15382 T15380 nsubj expression,be
R4426 T15371 T15366 prep in,Lack
R4427 T15383 T15380 aux might,be
R4428 T15384 T15380 acomp responsible,be
R4429 T15478 T15476 pobj expression,of
R4430 T15385 T15384 prep for,responsible
R4431 T15479 T15475 prep in,lack
R4432 T15386 T15387 amod proper,targeting
R4433 T15480 T15481 amod proprioceptive,cells
R4434 T15387 T15385 pobj targeting,for
R4435 T15481 T15479 pobj cells,in
R4436 T15482 T15455 punct .,suggest
R4437 T15388 T15387 compound axon,targeting
R4438 T15389 T15387 cc and,targeting
R4439 T15484 T15485 poss Our,results
R4440 T15485 T15487 nsubj results,suggest
R4441 T15486 T15485 amod present,results
R4442 T15390 T15391 compound muscle,spindle
R4443 T15488 T15489 mark that,acts
R4444 T15391 T15392 compound spindle,differentiation
R4445 T15489 T15487 ccomp acts,suggest
R4446 T15490 T15489 nsubj NT,acts
R4447 T15491 T15490 punct -,NT
R4448 T15392 T15387 conj differentiation,targeting
R4449 T15492 T15490 nummod 3,NT
R4450 T15493 T15489 prep as,acts
R4451 T15393 T15367 punct .,suggests
R4452 T15494 T15495 det a,cue
R4453 T15495 T15493 pobj cue,as
R4454 T15496 T15497 amod short,range
R4455 T15497 T15495 compound range,cue
R4456 T15498 T15497 punct -,range
R4457 T15499 T15500 compound axon,guidance
R4458 T15500 T15495 compound guidance,cue
R4459 T15501 T15489 prep for,acts
R4460 T15395 T15396 advmod Presently,rule
R4461 T15502 T15503 amod proprioceptive,axons
R4462 T15503 T15501 pobj axons,for
R4463 T15504 T15489 advmod centrally,acts
R4464 T15505 T15504 cc and,centrally
R4465 T15397 T15396 nsubj we,rule
R4466 T15506 T15504 conj peripherally,centrally
R4467 T15507 T15489 punct ", ",acts
R4468 T15508 T15509 mark as,navigate
R4469 T15509 T15489 advcl navigate,acts
R4470 T15398 T15396 aux can,rule
R4471 T15510 T15509 nsubj they,navigate
R4472 T15511 T15509 prep to,navigate
R4473 T15512 T15513 poss their,targets
R4474 T15399 T15396 neg not,rule
R4475 T15513 T15511 pobj targets,to
R4476 T15514 T15509 advcl using,navigate
R4477 T15400 T15396 advmod completely,rule
R4478 T15515 T15516 amod other,cues
R4479 T15516 T15514 dobj cues,using
R4480 T15517 T15518 compound axon,guidance
R4481 T15518 T15516 compound guidance,cues
R4482 T15401 T15396 prt out,rule
R4483 T15519 T15487 punct .,suggest
R4484 T15402 T15403 det this,possibility
R4485 T15521 T15522 prep In,terminate
R4486 T15523 T15524 poss its,absence
R4487 T15403 T15396 dobj possibility,rule
R4488 T15524 T15521 pobj absence,In
R4489 T15525 T15522 punct ", ",terminate
R4490 T15526 T15527 det these,axons
R4491 T15404 T15396 punct .,rule
R4492 T15527 T15522 nsubj axons,terminate
R4493 T15528 T15522 prep in,terminate
R4494 T15406 T15407 advmod However,noted
R4495 T15529 T15530 amod inappropriate,loci
R4496 T15530 T15528 pobj loci,in
R4497 T15531 T15522 punct .,terminate
R4498 T15408 T15407 punct ", ",noted
R4499 T15533 T15534 advmod However,be
R4500 T15535 T15534 punct ", ",be
R4501 T15536 T15534 nsubj NT,be
R4502 T15409 T15410 det no,defects
R4503 T15537 T15536 punct -,NT
R4504 T15538 T15536 nummod 3,NT
R4505 T15410 T15407 nsubjpass defects,noted
R4506 T15539 T15534 aux may,be
R4507 T15540 T15534 neg not,be
R4508 T15541 T15542 det the,molecule
R4509 T15542 T15534 attr molecule,be
R4510 T15543 T15542 amod only,molecule
R4511 T15544 T15545 dep that,plays
R4512 T15411 T15410 prep in,defects
R4513 T15545 T15542 relcl plays,molecule
R4514 T15546 T15547 det a,role
R4515 T15547 T15545 dobj role,plays
R4516 T15412 T15413 compound axon,pathfinding
R4517 T15548 T15545 prep in,plays
R4518 T15549 T15548 pobj targeting,in
R4519 T15550 T15549 cc and,targeting
R4520 T15413 T15411 pobj pathfinding,in
R4521 T15551 T15552 amod terminal,branching
R4522 T15552 T15549 conj branching,targeting
R4523 T15414 T15410 prep along,defects
R4524 T15553 T15549 prep of,targeting
R4525 T15554 T15555 amod sensory,axons
R4526 T15555 T15553 pobj axons,of
R4527 T15415 T15416 det the,arc
R4528 T15556 T15549 prep in,targeting
R4529 T15557 T15558 det the,cord
R4530 T15558 T15556 pobj cord,in
R4531 T15416 T15414 pobj arc,along
R4532 T15559 T15558 amod ventral,cord
R4533 T15560 T15558 amod spinal,cord
R4534 T15561 T15534 punct .,be
R4535 T15417 T15416 amod monosynaptic,arc
R4536 T15563 T15564 nsubj NT,acts
R4537 T15418 T15416 compound reflex,arc
R4538 T15565 T15563 punct -,NT
R4539 T15566 T15563 nummod 3,NT
R4540 T15419 T15414 cc or,along
R4541 T15567 T15568 advmod most,likely
R4542 T15568 T15564 advmod likely,acts
R4543 T15420 T15414 conj in,along
R4544 T15569 T15564 advmod cooperatively,acts
R4545 T15421 T15422 compound muscle,spindle
R4546 T15570 T15564 prep with,acts
R4547 T15571 T15572 amod other,molecules
R4548 T15572 T15570 pobj molecules,with
R4549 T15422 T15423 compound spindle,differentiation
R4550 T15573 T15574 compound axon,guidance
R4551 T15574 T15572 compound guidance,molecules
R4552 T15575 T15570 cc or,with
R4553 T15423 T15420 pobj differentiation,in
R4554 T15576 T15570 conj by,with
R4555 T15577 T15576 pcomp regulating,by
R4556 T15424 T15407 aux have,noted
R4557 T15578 T15577 dobj expression,regulating
R4558 T15579 T15578 prep of,expression
R4559 T15580 T15581 advmod yet,identified
R4560 T15581 T15579 pobj identified,of
R4561 T15582 T15581 aux to,identified
R4562 T15583 T15581 auxpass be,identified
R4563 T15425 T15407 auxpass been,noted
R4564 T15426 T15407 prep in,noted
R4565 T15584 T15585 amod proprioceptive,neuron
R4566 T15585 T15586 npadvmod neuron,specific
R4567 T15586 T15581 amod specific,identified
R4568 T15427 T15428 compound PV,KO
R4569 T15587 T15586 punct -,specific
R4570 T15588 T15589 compound receptors,ligands
R4571 T15428 T15429 compound KO,mice
R4572 T15589 T15581 appos ligands,identified
R4573 T15590 T15589 punct /,ligands
R4574 T15591 T15577 prep for,regulating
R4575 T15429 T15426 pobj mice,in
R4576 T15592 T15593 amod numerous,cues
R4577 T15593 T15591 pobj cues,for
R4578 T15594 T15595 compound axon,guidance
R4579 T15430 T15429 punct ", ",mice
R4580 T15595 T15593 compound guidance,cues
R4581 T15596 T15564 punct .,acts
R4582 T15431 T15432 dep which,develop
R4583 T15432 T15429 relcl develop,mice
R4584 T15433 T15432 advmod normally,develop
R4585 T15434 T15432 cc and,develop
R4586 T15435 T15432 conj show,develop
R4587 T15436 T15437 det no,changes
R4588 T15437 T15435 dobj changes,show
R4589 T15438 T15437 amod apparent,changes
R4590 T15439 T15437 prep in,changes
R4591 T15440 T15441 poss their,behavior
R4592 T15441 T15439 pobj behavior,in
R4593 T15442 T15441 cc or,behavior
R4594 T15443 T15444 amod physical,activity
R4595 T15444 T15441 conj activity,behavior
R4596 T15445 T15446 punct (,Schwaller
R4597 T15446 T15407 meta Schwaller,noted
R4598 T15447 T15446 nmod et,Schwaller
R4599 T15448 T15446 nmod al.,Schwaller
R4600 T15449 T15446 nummod 1999,Schwaller
R4601 T15450 T15446 punct ),Schwaller
R4602 T15451 T15407 punct .,noted
R4603 T15453 T15454 det These,observations
R4604 T15454 T15455 nsubj observations,suggest
R4605 T15456 T15457 mark that,be
R4606 T15457 T15455 ccomp be,suggest
R4607 T15458 T15459 amod axonal,defects
R4608 T15459 T15457 nsubj defects,be
R4609 T15460 T15459 amod targeting,defects
R4610 T15461 T15459 prep in,defects
R4611 T15462 T15463 nmod Bax,KO
R4612 T15463 T15469 compound KO,mice
R4613 T15464 T15462 punct /,Bax
R4614 T15465 T15462 appos NT,Bax
R4615 T15466 T15465 punct -,NT
R4616 T15467 T15465 nummod 3,NT
R4617 T15468 T15463 amod double,KO
R4618 T15469 T15461 pobj mice,in
R4619 T15470 T15457 aux can,be
R4620 T15471 T15457 neg not,be
R4621 T15472 T15457 advmod simply,be
R4622 T15473 T15457 prep due,be
R4623 T15474 T15473 pcomp to,due
R4624 T15475 T15473 pobj lack,due
R4625 T15476 T15475 prep of,lack
R4626 T15477 T15478 compound PV,expression
R4627 T16204 T16203 prep of,Generation
R4628 T16205 T16206 amod double,KOs
R4629 T16206 T16204 pobj KOs,of
R4630 T16207 T16203 punct .,Generation
R4631 T16209 T16210 nsubj We,crossed
R4632 T16211 T16212 compound Bax,KO
R4633 T16212 T16213 compound KO,females
R4634 T16213 T16210 dobj females,crossed
R4635 T16214 T16213 prep on,females
R4636 T16215 T16216 det a,background
R4637 T16216 T16214 pobj background,on
R4638 T16217 T16216 nmod C57BL,background
R4639 T16218 T16217 punct /,C57BL
R4640 T16219 T16217 nummod 6,C57BL
R4641 T16220 T16221 punct (,Laboratory
R4642 T16221 T16213 parataxis Laboratory,females
R4643 T16222 T16221 compound Jackson,Laboratory
R4644 T16223 T16221 punct ", ",Laboratory
R4645 T16224 T16225 compound Bar,Harbor
R4646 T16225 T16221 npadvmod Harbor,Laboratory
R4647 T16226 T16221 punct ", ",Laboratory
R4648 T16227 T16221 npadvmod Maine,Laboratory
R4649 T16228 T16221 punct ", ",Laboratory
R4650 T16229 T16230 compound United,States
R4651 T16230 T16221 npadvmod States,Laboratory
R4652 T16231 T16221 punct ),Laboratory
R4653 T16232 T16210 prep to,crossed
R4654 T16233 T16234 nmod NT,heterozygote
R4655 T16234 T16237 compound heterozygote,males
R4656 T16235 T16233 punct -,NT
R4657 T16236 T16233 nummod 3,NT
R4658 T16237 T16232 pobj males,to
R4659 T16238 T16210 prep on,crossed
R4660 T16239 T16240 det a,background
R4661 T16240 T16238 pobj background,on
R4662 T16241 T16242 nummod 129,Sv
R4663 T16242 T16240 compound Sv,background
R4664 T16243 T16244 aux to,generate
R4665 T16244 T16210 advcl generate,crossed
R4666 T16245 T16246 amod double,heterozygote
R4667 T16246 T16247 compound heterozygote,animals
R4668 T16247 T16244 dobj animals,generate
R4669 T16248 T16210 punct .,crossed
R4670 T16250 T16251 nsubjpass Progeny,genotyped
R4671 T16252 T16251 auxpass was,genotyped
R4672 T16253 T16251 prep with,genotyped
R4673 T16254 T16253 pobj PCR,with
R4674 T16255 T16251 punct ", ",genotyped
R4675 T16256 T16251 cc and,genotyped
R4676 T16257 T16258 nsubjpass animals,bred
R4677 T16258 T16251 conj bred,genotyped
R4678 T16259 T16257 amod heterozygous,animals
R4679 T16260 T16259 prep for,heterozygous
R4680 T16261 T16262 det both,genes
R4681 T16262 T16260 pobj genes,for
R4682 T16263 T16258 auxpass were,bred
R4683 T16264 T16265 aux to,obtain
R4684 T16265 T16258 advcl obtain,bred
R4685 T16266 T16267 det the,KOs
R4686 T16267 T16265 dobj KOs,obtain
R4687 T16268 T16267 amod double,KOs
R4688 T16269 T16258 punct .,bred
R4689 T16271 T16272 nsubj Primers,were
R4690 T16273 T16271 acl used,Primers
R4691 T16274 T16273 prep for,used
R4692 T16275 T16276 det the,locus
R4693 T16276 T16274 pobj locus,for
R4694 T16277 T16276 compound Bax,locus
R4695 T16278 T16272 attr R661,were
R4696 T16279 T16278 punct ", ",R661
R4697 T16280 T16281 compound GTT,GG
R4698 T16281 T16278 appos GG,R661
R4699 T16282 T16281 compound GAC,GG
R4700 T16283 T16281 compound CAG,GG
R4701 T16284 T16281 compound AGT,GG
R4702 T16285 T16281 compound GGC,GG
R4703 T16286 T16281 compound GTA,GG
R4704 T16287 T16278 punct ;,R661
R4705 T16288 T16278 conj R662,R661
R4706 T16289 T16288 punct ", ",R662
R4707 T16290 T16291 compound CCG,GG
R4708 T16291 T16288 appos GG,R662
R4709 T16292 T16291 compound CTT,GG
R4710 T16293 T16291 compound CCA,GG
R4711 T16294 T16291 compound TTG,GG
R4712 T16295 T16291 compound CTC,GG
R4713 T16296 T16291 compound AGC,GG
R4714 T16297 T16288 punct ;,R662
R4715 T16298 T16288 cc and,R662
R4716 T16299 T16288 conj R663,R662
R4717 T16300 T16299 punct ", ",R663
R4718 T16301 T16302 compound GAG,ATG
R4719 T16302 T16299 appos ATG,R663
R4720 T16303 T16302 compound CTG,ATG
R4721 T16304 T16302 compound ATC,ATG
R4722 T16305 T16302 compound AGA,ATG
R4723 T16306 T16302 compound ACC,ATG
R4724 T16307 T16302 compound ATC,ATG
R4725 T16308 T16272 punct .,were
R4726 T16310 T16311 nsubj Primers,were
R4727 T16312 T16310 acl used,Primers
R4728 T16313 T16312 prep for,used
R4729 T16314 T16315 det the,locus
R4730 T16315 T16313 pobj locus,for
R4731 T16316 T16315 nmod NT,locus
R4732 T16317 T16316 punct -,NT
R4733 T16318 T16316 nummod 3,NT
R4734 T16319 T16311 attr NT3A,were
R4735 T16320 T16319 punct ", ",NT3A
R4736 T16321 T16322 compound CGT,AC
R4737 T16322 T16319 appos AC,NT3A
R4738 T16323 T16322 compound GGT,AC
R4739 T16324 T16322 compound GAG,AC
R4740 T16325 T16322 compound GTT,AC
R4741 T16326 T16322 compound CTA,AC
R4742 T16327 T16322 compound TTG,AC
R4743 T16328 T16322 compound GCT,AC
R4744 T16329 T16319 punct ;,NT3A
R4745 T16330 T16319 conj NT3B,NT3A
R4746 T16331 T16330 punct ", ",NT3B
R4747 T16332 T16333 compound CAG,GAG
R4748 T16333 T16330 appos GAG,NT3B
R4749 T16334 T16333 compound AGC,GAG
R4750 T16335 T16333 compound ACC,GAG
R4751 T16336 T16333 compound CTG,GAG
R4752 T16337 T16333 compound CCC,GAG
R4753 T16338 T16333 compound AAA,GAG
R4754 T16339 T16333 compound GCA,GAG
R4755 T16340 T16330 punct ;,NT3B
R4756 T16341 T16330 conj NT3R,NT3B
R4757 T16342 T16341 punct ", ",NT3R
R4758 T16343 T16344 compound CCT,CC
R4759 T16344 T16341 appos CC,NT3R
R4760 T16345 T16344 compound TGA,CC
R4761 T16346 T16344 compound CAA,CC
R4762 T16347 T16344 compound TAC,CC
R4763 T16348 T16344 compound TGA,CC
R4764 T16349 T16344 compound ATG,CC
R4765 T16350 T16341 punct ;,NT3R
R4766 T16351 T16341 cc and,NT3R
R4767 T16352 T16341 conj NEOF,NT3R
R4768 T16353 T16352 punct ", ",NEOF
R4769 T16354 T16355 compound GGG,AGG
R4770 T16355 T16352 appos AGG,NEOF
R4771 T16356 T16355 compound AAC,AGG
R4772 T16357 T16355 compound TTC,AGG
R4773 T16358 T16355 compound CTG,AGG
R4774 T16359 T16355 compound ACT,AGG
R4775 T16360 T16311 punct .,were
R4776 T16362 T16363 nmod WT,littermates
R4777 T16363 T16373 nsubjpass littermates,used
R4778 T16364 T16362 punct ", ",WT
R4779 T16365 T16366 compound Bax,KO
R4780 T16366 T16362 conj KO,WT
R4781 T16367 T16366 punct ", ",KO
R4782 T16368 T16366 cc and,KO
R4783 T16369 T16370 nmod NT,KO
R4784 T16370 T16366 conj KO,KO
R4785 T16371 T16369 punct -,NT
R4786 T16372 T16369 nummod 3,NT
R4787 T16374 T16373 auxpass were,used
R4788 T16375 T16373 prep as,used
R4789 T16376 T16375 pobj controls,as
R4790 T16377 T16373 punct .,used
R4791 T16379 T16380 det A,total
R4792 T16380 T16381 nsubjpass total,analyzed
R4793 T16381 T16393 ccomp analyzed,were
R4794 T16382 T16380 prep of,total
R4795 T16383 T16384 nummod 11,mice
R4796 T16384 T16382 pobj mice,of
R4797 T16385 T16386 nmod Bax,KO
R4798 T16386 T16384 compound KO,mice
R4799 T16387 T16385 punct /,Bax
R4800 T16388 T16385 appos NT,Bax
R4801 T16389 T16388 punct -,NT
R4802 T16390 T16388 nummod 3,NT
R4803 T16391 T16386 amod double,KO
R4804 T16392 T16381 auxpass were,analyzed
R4805 T16394 T16393 punct ", ",were
R4806 T16395 T16393 prep of,were
R4807 T16396 T16395 pobj these,of
R4808 T16397 T16393 nsubj nine,were
R4809 T16398 T16399 compound P0,pups
R4810 T16399 T16393 attr pups,were
R4811 T16400 T16393 punct .,were
R4812 T16402 T16403 det The,colony
R4813 T16403 T16405 nsubjpass colony,received
R4814 T16404 T16403 compound p75,colony
R4815 T16406 T16403 prep on,colony
R4816 T16407 T16408 det a,background
R4817 T16408 T16406 pobj background,on
R4818 T16409 T16410 nummod 129,S1
R4819 T16410 T16408 compound S1,background
R4820 T16411 T16405 auxpass was,received
R4821 T16412 T16405 prep from,received
R4822 T16413 T16414 compound Jackson,Laboratory
R4823 T16414 T16412 pobj Laboratory,from
R4824 T16415 T16405 punct .,received
R4825 T16417 T16418 nsubj We,used
R4826 T16419 T16420 compound tail,DNA
R4827 T16420 T16418 dobj DNA,used
R4828 T16421 T16422 aux to,genotype
R4829 T16422 T16418 advcl genotype,used
R4830 T16423 T16422 dobj animals,genotype
R4831 T16424 T16422 advcl using,genotype
R4832 T16425 T16426 det the,primers
R4833 T16426 T16424 dobj primers,using
R4834 T16427 T16426 appos IMR0013,primers
R4835 T16428 T16427 punct ", ",IMR0013
R4836 T16429 T16430 compound CTT,TC
R4837 T16430 T16427 appos TC,IMR0013
R4838 T16431 T16430 compound GGG,TC
R4839 T16432 T16430 compound TGG,TC
R4840 T16433 T16430 compound AGA,TC
R4841 T16434 T16430 compound GGC,TC
R4842 T16435 T16430 compound TAT,TC
R4843 T16436 T16427 punct ;,IMR0013
R4844 T16437 T16427 conj IMR0014,IMR0013
R4845 T16438 T16437 punct ", ",IMR0014
R4846 T16439 T16440 compound AGG,TC
R4847 T16440 T16437 appos TC,IMR0014
R4848 T16441 T16440 compound TGA,TC
R4849 T16442 T16440 compound GAT,TC
R4850 T16443 T16440 compound GAC,TC
R4851 T16444 T16440 compound AGG,TC
R4852 T16445 T16440 compound AGA,TC
R4853 T16446 T16437 punct (,IMR0014
R4854 T16447 T16448 amod generic,primers
R4855 T16448 T16437 appos primers,IMR0014
R4856 T16449 T16448 compound neo,primers
R4857 T16450 T16437 punct ),IMR0014
R4858 T16451 T16437 punct ;,IMR0014
R4859 T16452 T16437 conj IMR0710,IMR0014
R4860 T16453 T16452 punct ", ",IMR0710
R4861 T16454 T16455 compound TGT,GAG
R4862 T16455 T16452 appos GAG,IMR0710
R4863 T16456 T16455 compound TAC,GAG
R4864 T16457 T16455 compound GTT,GAG
R4865 T16458 T16455 compound CTC,GAG
R4866 T16459 T16455 compound TGA,GAG
R4867 T16460 T16455 compound CGT,GAG
R4868 T16461 T16455 compound GGT,GAG
R4869 T16462 T16452 punct ;,IMR0710
R4870 T16463 T16452 cc and,IMR0710
R4871 T16464 T16452 conj IMR0711,IMR0710
R4872 T16465 T16464 punct ", ",IMR0711
R4873 T16466 T16467 compound TCA,TC
R4874 T16467 T16464 appos TC,IMR0711
R4875 T16468 T16467 compound GCC,TC
R4876 T16469 T16467 compound CAG,TC
R4877 T16470 T16467 compound GGT,TC
R4878 T16471 T16467 compound GTG,TC
R4879 T16472 T16467 compound CAC,TC
R4880 T16473 T16474 punct (,locus
R4881 T16474 T16464 appos locus,IMR0711
R4882 T16475 T16474 compound p75,locus
R4883 T16476 T16464 punct ),IMR0711
R4884 T16477 T16418 punct .,used
R4885 T16479 T16480 prep For,considered
R4886 T16481 T16482 amod embryonic,experiments
R4887 T16482 T16479 pobj experiments,For
R4888 T16483 T16480 punct ", ",considered
R4889 T16484 T16480 nsubjpass day,considered
R4890 T16485 T16484 prep of,day
R4891 T16486 T16487 compound plug,positivity
R4892 T16487 T16485 pobj positivity,of
R4893 T16488 T16480 auxpass was,considered
R4894 T16489 T16480 oprd E0,considered
R4895 T16490 T16480 punct .,considered
R4896 T16492 T16493 nsubjpass All,approved
R4897 T16494 T16492 prep of,All
R4898 T16495 T16496 det the,protocols
R4899 T16496 T16494 pobj protocols,of
R4900 T16497 T16496 acl used,protocols
R4901 T16498 T16497 prep in,used
R4902 T16499 T16500 det this,study
R4903 T16500 T16498 pobj study,in
R4904 T16501 T16493 auxpass were,approved
R4905 T16502 T16493 agent by,approved
R4906 T16503 T16504 det the,Committee
R4907 T16504 T16502 pobj Committee,by
R4908 T16505 T16506 nmod Louisiana,University
R4909 T16506 T16508 nmod University,Center
R4910 T16507 T16506 nmod State,University
R4911 T16508 T16504 nmod Center,Committee
R4912 T16509 T16510 nmod Health,Sciences
R4913 T16510 T16508 nmod Sciences,Center
R4914 T16511 T16512 nmod Institutional,Animal
R4915 T16512 T16513 nmod Animal,Care
R4916 T16513 T16504 nmod Care,Committee
R4917 T16514 T16513 cc and,Care
R4918 T16515 T16513 conj Use,Care
R4919 T16516 T16493 cc and,approved
R4920 T16517 T16493 conj conformed,approved
R4921 T16518 T16517 prep to,conformed
R4922 T16519 T16520 det the,guidelines
R4923 T16520 T16518 pobj guidelines,to
R4924 T16521 T16522 nmod National,Institutes
R4925 T16522 T16520 nmod Institutes,guidelines
R4926 T16523 T16522 prep of,Institutes
R4927 T16524 T16523 pobj Health,of
R4928 T16525 T16520 prep for,guidelines
R4929 T16526 T16525 pobj use,for
R4930 T16527 T16526 prep of,use
R4931 T16528 T16529 amod experimental,animals
R4932 T16529 T16527 pobj animals,of
R4933 T16530 T16493 punct .,approved
R4934 T16880 T16881 compound TrkA,TrkC
R4935 T16881 T16883 compound TrkC,immunohistochemistry
R4936 T16882 T16881 punct /,TrkC
R4937 T16884 T16883 punct .,immunohistochemistry
R4938 T16886 T16887 amod Frozen,sections
R4939 T16887 T16890 nsubjpass sections,blocked
R4940 T16888 T16889 amod spinal,cord
R4941 T16889 T16887 compound cord,sections
R4942 T16891 T16887 punct (,sections
R4943 T16892 T16893 nummod 10,μm
R4944 T16893 T16894 npadvmod μm,thick
R4945 T16894 T16887 amod thick,sections
R4946 T16895 T16887 punct ),sections
R4947 T16896 T16890 auxpass were,blocked
R4948 T16897 T16890 cc and,blocked
R4949 T16898 T16890 conj incubated,blocked
R4950 T16899 T16898 prep in,incubated
R4951 T16900 T16901 det a,cocktail
R4952 T16901 T16899 pobj cocktail,in
R4953 T16902 T16901 prep of,cocktail
R4954 T16903 T16902 pobj rabbit,of
R4955 T16904 T16903 amod anti-TrkA,rabbit
R4956 T16905 T16903 cc and,rabbit
R4957 T16906 T16907 nmod goat,antibodies
R4958 T16907 T16903 conj antibodies,rabbit
R4959 T16908 T16906 amod anti-TrkC,goat
R4960 T16909 T16910 punct (,gift
R4961 T16910 T16907 parataxis gift,antibodies
R4962 T16911 T16910 prep of,gift
R4963 T16912 T16913 compound Dr.,Reichardt
R4964 T16913 T16911 pobj Reichardt,of
R4965 T16914 T16910 punct ;,gift
R4966 T16915 T16910 meta Huang,gift
R4967 T16916 T16915 nmod et,Huang
R4968 T16917 T16915 nmod al.,Huang
R4969 T16918 T16915 nummod 1999,Huang
R4970 T16919 T16910 punct ),gift
R4971 T16920 T16898 punct ", ",incubated
R4972 T16921 T16898 conj followed,incubated
R4973 T16922 T16921 agent by,followed
R4974 T16923 T16924 det a,cocktail
R4975 T16924 T16922 pobj cocktail,by
R4976 T16925 T16924 prep of,cocktail
R4977 T16926 T16927 npadvmod CY3,conjugated
R4978 T16927 T16928 amod conjugated,donkey
R4979 T16928 T16925 pobj donkey,of
R4980 T16929 T16928 amod anti-rabbit,donkey
R4981 T16930 T16928 cc and,donkey
R4982 T16931 T16932 npadvmod FITC,conjugated
R4983 T16932 T16933 amod conjugated,donkey
R4984 T16933 T16934 nmod donkey,antibodies
R4985 T16934 T16928 conj antibodies,donkey
R4986 T16935 T16933 amod anti-goat,donkey
R4987 T16936 T16937 punct (,Chemicon
R4988 T16937 T16924 parataxis Chemicon,cocktail
R4989 T16938 T16937 punct ", ",Chemicon
R4990 T16939 T16937 npadvmod Temecula,Chemicon
R4991 T16940 T16937 punct ", ",Chemicon
R4992 T16941 T16937 npadvmod California,Chemicon
R4993 T16942 T16937 punct ", ",Chemicon
R4994 T16943 T16944 compound United,States
R4995 T16944 T16937 npadvmod States,Chemicon
R4996 T16945 T16937 punct ),Chemicon
R4997 T16946 T16924 prep in,cocktail
R4998 T16947 T16948 det the,presence
R4999 T16948 T16946 pobj presence,in
R5000 T16949 T16948 prep of,presence
R5001 T16950 T16951 nummod 0.3,%
R5002 T16951 T16952 compound %,TritonX
R5003 T16952 T16949 pobj TritonX,of
R5004 T16953 T16952 punct -,TritonX
R5005 T16954 T16952 nummod 100,TritonX
R5006 T16955 T16952 cc and,TritonX
R5007 T16956 T16957 nummod 10,%
R5008 T16957 T16958 nmod %,serum
R5009 T16958 T16952 conj serum,TritonX
R5010 T16959 T16958 amod normal,serum
R5011 T16960 T16958 compound donkey,serum
R5012 T16961 T16890 punct .,blocked
R5013 T16963 T16964 prep For,reacted
R5014 T16965 T16966 compound PV,immunohistochemistry
R5015 T16966 T16963 pobj immunohistochemistry,For
R5016 T16967 T16964 punct ", ",reacted
R5017 T16968 T16964 nsubjpass sections,reacted
R5018 T16969 T16964 auxpass were,reacted
R5019 T16970 T16964 prep with,reacted
R5020 T16971 T16972 amod monoclonal,antibody
R5021 T16972 T16970 pobj antibody,with
R5022 T16973 T16972 nmod mouse,antibody
R5023 T16974 T16972 amod anti-PV,antibody
R5024 T16975 T16976 punct (,Sigma
R5025 T16976 T16972 parataxis Sigma,antibody
R5026 T16977 T16976 punct ", ",Sigma
R5027 T16978 T16979 compound St.,Louis
R5028 T16979 T16976 npadvmod Louis,Sigma
R5029 T16980 T16976 punct ", ",Sigma
R5030 T16981 T16976 npadvmod Missouri,Sigma
R5031 T16982 T16976 punct ", ",Sigma
R5032 T16983 T16984 compound United,States
R5033 T16984 T16976 npadvmod States,Sigma
R5034 T16985 T16976 punct ),Sigma
R5035 T16986 T16964 punct ", ",reacted
R5036 T16987 T16964 cc and,reacted
R5037 T16988 T16964 conj developed,reacted
R5038 T16989 T16988 agent by,developed
R5039 T16990 T16991 nmod Vector,fluorescein
R5040 T16991 T16992 nmod fluorescein,kit
R5041 T16992 T16989 pobj kit,by
R5042 T16993 T16992 nmod mouse,kit
R5043 T16994 T16993 prep on,mouse
R5044 T16995 T16994 pobj mouse,on
R5045 T16996 T16997 punct (,Laboratories
R5046 T16997 T16992 parataxis Laboratories,kit
R5047 T16998 T16997 compound Vector,Laboratories
R5048 T16999 T16997 punct ", ",Laboratories
R5049 T17000 T16997 npadvmod Burlingame,Laboratories
R5050 T17001 T16997 punct ", ",Laboratories
R5051 T17002 T16997 npadvmod California,Laboratories
R5052 T17003 T16997 punct ", ",Laboratories
R5053 T17004 T17005 compound United,States
R5054 T17005 T16997 npadvmod States,Laboratories
R5055 T17006 T16997 punct ),Laboratories
R5056 T17007 T16964 punct .,reacted
R5057 T17009 T17010 prep For,counted
R5058 T17011 T17012 compound quantification,purposes
R5059 T17012 T17009 pobj purposes,For
R5060 T17013 T17010 punct ", ",counted
R5061 T17014 T17015 npadvmod TrkA,labeled
R5062 T17015 T17020 amod labeled,cells
R5063 T17016 T17014 punct -,TrkA
R5064 T17017 T17014 cc and,TrkA
R5065 T17018 T17014 conj TrkC,TrkA
R5066 T17019 T17015 punct -,labeled
R5067 T17020 T17010 nsubjpass cells,counted
R5068 T17021 T17020 prep from,cells
R5069 T17022 T17023 nummod four,DRGs
R5070 T17023 T17021 pobj DRGs,from
R5071 T17024 T17023 amod different,DRGs
R5072 T17025 T17023 prep of,DRGs
R5073 T17026 T17027 det each,genotype
R5074 T17027 T17025 pobj genotype,of
R5075 T17028 T17027 cc and,genotype
R5076 T17029 T17027 conj age,genotype
R5077 T17030 T17027 acl studied,genotype
R5078 T17031 T17010 auxpass were,counted
R5079 T17032 T17010 punct ", ",counted
R5080 T17033 T17010 cc and,counted
R5081 T17034 T17035 nsubj ratios,plotted
R5082 T17035 T17010 conj plotted,counted
R5083 T17036 T17010 punct .,counted
R5084 T17352 T17353 compound Muscle,spindle
R5085 T17353 T17354 compound spindle,detection
R5086 T17355 T17354 punct .,detection
R5087 T17357 T17358 compound Gastrocnemius,muscle
R5088 T17358 T17359 nsubjpass muscle,dissected
R5089 T17360 T17359 auxpass was,dissected
R5090 T17361 T17359 prt out,dissected
R5091 T17362 T17359 prep in,dissected
R5092 T17363 T17364 compound P0,pups
R5093 T17364 T17362 pobj pups,in
R5094 T17365 T17359 cc and,dissected
R5095 T17366 T17359 conj sectioned,dissected
R5096 T17367 T17366 advmod longitudinally,sectioned
R5097 T17368 T17359 punct ", ",dissected
R5098 T17369 T17359 cc or,dissected
R5099 T17370 T17359 punct ", ",dissected
R5100 T17371 T17372 prep in,sectioned
R5101 T17372 T17359 conj sectioned,dissected
R5102 T17373 T17374 det some,cases
R5103 T17374 T17371 pobj cases,in
R5104 T17375 T17372 punct ", ",sectioned
R5105 T17376 T17377 det the,leg
R5106 T17377 T17372 nsubjpass leg,sectioned
R5107 T17378 T17377 amod whole,leg
R5108 T17379 T17377 prep at,leg
R5109 T17380 T17381 det the,level
R5110 T17381 T17379 pobj level,at
R5111 T17382 T17381 prep of,level
R5112 T17383 T17384 compound gastrocnemius,muscle
R5113 T17384 T17382 pobj muscle,of
R5114 T17385 T17384 prep with,muscle
R5115 T17386 T17387 amod tibial,nerve
R5116 T17387 T17385 pobj nerve,with
R5117 T17388 T17372 auxpass was,sectioned
R5118 T17389 T17372 prep in,sectioned
R5119 T17390 T17391 compound cross,section
R5120 T17391 T17389 pobj section,in
R5121 T17392 T17372 punct .,sectioned
R5122 T17394 T17395 nsubj Sections,incubated
R5123 T17396 T17395 aux were,incubated
R5124 T17397 T17395 prep with,incubated
R5125 T17398 T17399 amod monoclonal,antibody
R5126 T17399 T17397 pobj antibody,with
R5127 T17400 T17399 compound S46,antibody
R5128 T17401 T17402 punct (,gift
R5129 T17402 T17399 parataxis gift,antibody
R5130 T17403 T17402 prep of,gift
R5131 T17404 T17405 compound Dr.,Stockdale
R5132 T17405 T17403 pobj Stockdale,of
R5133 T17406 T17402 punct ),gift
R5134 T17407 T17399 amod reactive,antibody
R5135 T17408 T17407 prep to,reactive
R5136 T17409 T17410 det the,isoform
R5137 T17410 T17408 pobj isoform,to
R5138 T17411 T17412 npadvmod spindle,specific
R5139 T17412 T17410 amod specific,isoform
R5140 T17413 T17412 punct -,specific
R5141 T17414 T17415 amod slow,tonic
R5142 T17415 T17410 nmod tonic,isoform
R5143 T17416 T17415 punct -,tonic
R5144 T17417 T17410 nmod myosin,isoform
R5145 T17418 T17419 amod heavy,chain
R5146 T17419 T17410 compound chain,isoform
R5147 T17420 T17395 cc and,incubated
R5148 T17421 T17395 conj developed,incubated
R5149 T17422 T17421 prep by,developed
R5150 T17423 T17424 nmod Vector,kit
R5151 T17424 T17422 pobj kit,by
R5152 T17425 T17424 nmod mouse,kit
R5153 T17426 T17425 prep on,mouse
R5154 T17427 T17426 pobj mouse,on
R5155 T17428 T17429 mark as,described
R5156 T17429 T17421 advcl described,developed
R5157 T17430 T17429 advmod above,described
R5158 T17431 T17395 punct ", ",incubated
R5159 T17432 T17395 advcl followed,incubated
R5160 T17433 T17432 agent by,followed
R5161 T17434 T17435 nmod rabbit,antibody
R5162 T17435 T17433 pobj antibody,by
R5163 T17436 T17437 amod anti-NF,M
R5164 T17437 T17435 compound M,antibody
R5165 T17438 T17437 punct -,M
R5166 T17439 T17440 punct (,Chemicon
R5167 T17440 T17435 parataxis Chemicon,antibody
R5168 T17441 T17440 punct ),Chemicon
R5169 T17442 T17435 cc and,antibody
R5170 T17443 T17444 nmod CY3,antibody
R5171 T17444 T17435 conj antibody,antibody
R5172 T17445 T17444 amod conjugated,antibody
R5173 T17446 T17444 nmod goat,antibody
R5174 T17447 T17444 amod anti-rabbit,antibody
R5175 T17448 T17449 punct (,Chemicon
R5176 T17449 T17444 parataxis Chemicon,antibody
R5177 T17450 T17449 punct ),Chemicon
R5178 T17451 T17432 prep in,followed
R5179 T17452 T17453 det a,protocol
R5180 T17453 T17451 pobj protocol,in
R5181 T17454 T17453 amod sequential,protocol
R5182 T17455 T17456 amod double,labeling
R5183 T17456 T17453 compound labeling,protocol
R5184 T17457 T17456 punct -,labeling
R5185 T17458 T17395 punct .,incubated
R5186 T17460 T17461 prep In,placed
R5187 T17462 T17463 det another,method
R5188 T17463 T17460 pobj method,In
R5189 T17464 T17461 punct ", ",placed
R5190 T17465 T17466 compound DiI,crystals
R5191 T17466 T17461 nsubjpass crystals,placed
R5192 T17467 T17461 auxpass were,placed
R5193 T17468 T17461 prep in,placed
R5194 T17469 T17468 pobj DRGs,in
R5195 T17470 T17469 prep of,DRGs
R5196 T17471 T17472 compound E17,embryos
R5197 T17472 T17470 pobj embryos,of
R5198 T17473 T17472 prep from,embryos
R5199 T17474 T17475 amod different,genotypes
R5200 T17475 T17473 pobj genotypes,from
R5201 T17476 T17477 punct (,2
R5202 T17477 T17472 parataxis 2,embryos
R5203 T17478 T17477 nsubj n,2
R5204 T17479 T17477 punct =,2
R5205 T17480 T17477 punct ),2
R5206 T17481 T17461 punct ", ",placed
R5207 T17482 T17461 cc and,placed
R5208 T17483 T17484 det the,muscle
R5209 T17484 T17486 nsubjpass muscle,isolated
R5210 T17485 T17484 compound gastrocnemius,muscle
R5211 T17486 T17461 conj isolated,placed
R5212 T17487 T17486 auxpass was,isolated
R5213 T17488 T17486 cc and,isolated
R5214 T17489 T17486 conj sectioned,isolated
R5215 T17490 T17489 prep into,sectioned
R5216 T17491 T17492 nummod 40,μm
R5217 T17492 T17494 npadvmod μm,thick
R5218 T17493 T17492 punct -,μm
R5219 T17494 T17496 amod thick,slices
R5220 T17495 T17494 punct -,thick
R5221 T17496 T17490 pobj slices,into
R5222 T17497 T17489 prep on,sectioned
R5223 T17498 T17499 det a,vibratome
R5224 T17499 T17497 pobj vibratome,on
R5225 T17500 T17486 punct .,isolated
R5226 T17771 T17772 compound DiI,labeling
R5227 T17773 T17772 punct .,labeling
R5228 T17775 T17776 amod Spinal,cords
R5229 T17776 T17777 nsubjpass cords,dissected
R5230 T17778 T17777 auxpass were,dissected
R5231 T17779 T17777 prt out,dissected
R5232 T17780 T17781 mark with,attached
R5233 T17781 T17777 advcl attached,dissected
R5234 T17782 T17783 det the,DRGs
R5235 T17783 T17781 nsubj DRGs,attached
R5236 T17784 T17777 punct ", ",dissected
R5237 T17785 T17786 compound motor,root
R5238 T17786 T17787 nsubjpass root,cut
R5239 T17787 T17777 conj cut,dissected
R5240 T17788 T17787 auxpass was,cut
R5241 T17789 T17790 aux to,prevent
R5242 T17790 T17787 advcl prevent,cut
R5243 T17791 T17790 dobj backfilling,prevent
R5244 T17792 T17791 prep of,backfilling
R5245 T17793 T17794 compound motor,neurons
R5246 T17794 T17792 pobj neurons,of
R5247 T17795 T17787 punct ", ",cut
R5248 T17796 T17787 cc and,cut
R5249 T17797 T17798 nsubjpass crystals,inserted
R5250 T17798 T17787 conj inserted,cut
R5251 T17799 T17797 prep of,crystals
R5252 T17800 T17801 nummod 1,perchlorate
R5253 T17801 T17799 pobj perchlorate,of
R5254 T17802 T17800 punct ",",1
R5255 T17803 T17800 appos 1,1
R5256 T17804 T17803 punct ′,1
R5257 T17805 T17801 punct -,perchlorate
R5258 T17806 T17801 nmod dioctadecyl,perchlorate
R5259 T17807 T17801 punct -,perchlorate
R5260 T17808 T17801 nummod 3,perchlorate
R5261 T17809 T17808 punct ",",3
R5262 T17810 T17808 appos 3,3
R5263 T17811 T17808 punct ",",3
R5264 T17812 T17808 appos 3,3
R5265 T17813 T17812 punct ′,3
R5266 T17814 T17808 punct ",",3
R5267 T17815 T17808 appos 3,3
R5268 T17816 T17815 punct ′,3
R5269 T17817 T17801 punct -,perchlorate
R5270 T17818 T17801 compound tetramethylindocarbocyanine,perchlorate
R5271 T17819 T17820 punct (,Probes
R5272 T17820 T17797 parataxis Probes,crystals
R5273 T17821 T17820 dep DiI,Probes
R5274 T17822 T17820 punct ;,Probes
R5275 T17823 T17820 compound Molecular,Probes
R5276 T17824 T17820 punct ", ",Probes
R5277 T17825 T17820 npadvmod Eugene,Probes
R5278 T17826 T17820 punct ", ",Probes
R5279 T17827 T17820 npadvmod Oregon,Probes
R5280 T17828 T17820 punct ", ",Probes
R5281 T17829 T17830 compound United,States
R5282 T17830 T17820 npadvmod States,Probes
R5283 T17831 T17820 punct ),Probes
R5284 T17832 T17798 auxpass were,inserted
R5285 T17833 T17798 prep in,inserted
R5286 T17834 T17833 pobj DRGs,in
R5287 T17835 T17798 punct .,inserted
R5288 T17837 T17838 amod Labeled,cords
R5289 T17838 T17840 nsubjpass cords,incubated
R5290 T17839 T17838 amod spinal,cords
R5291 T17841 T17840 auxpass were,incubated
R5292 T17842 T17840 prep at,incubated
R5293 T17843 T17844 nummod 37,°C
R5294 T17844 T17842 pobj °C,at
R5295 T17845 T17840 prep for,incubated
R5296 T17846 T17847 nummod 8,d
R5297 T17847 T17845 pobj d,for
R5298 T17848 T17840 cc and,incubated
R5299 T17849 T17840 conj sectioned,incubated
R5300 T17850 T17849 prep on,sectioned
R5301 T17851 T17852 det a,vibrotome
R5302 T17852 T17850 pobj vibrotome,on
R5303 T17853 T17849 prep at,sectioned
R5304 T17854 T17855 nummod 100,μm
R5305 T17855 T17853 pobj μm,at
R5306 T17856 T17840 punct .,incubated
R5307 T17858 T17859 nsubjpass Sections,observed
R5308 T17860 T17859 auxpass were,observed
R5309 T17861 T17859 prep under,observed
R5310 T17862 T17863 det the,microscope
R5311 T17863 T17861 pobj microscope,under
R5312 T17864 T17863 amod fluorescent,microscope
R5313 T17865 T17859 cc and,observed
R5314 T17866 T17859 conj photographed,observed
R5315 T17867 T17859 punct ", ",observed
R5316 T17868 T17859 cc and,observed
R5317 T17869 T17870 nsubjpass images,transferred
R5318 T17870 T17859 conj transferred,observed
R5319 T17871 T17870 auxpass were,transferred
R5320 T17872 T17870 prep to,transferred
R5321 T17873 T17874 compound Adobe,Photoshop
R5322 T17874 T17872 pobj Photoshop,to
R5323 T17875 T17870 punct ", ",transferred
R5324 T17876 T17870 conj inverted,transferred
R5325 T17877 T17876 punct ", ",inverted
R5326 T17878 T17876 cc and,inverted
R5327 T17879 T17876 conj adjusted,inverted
R5328 T17880 T17879 prep for,adjusted
R5329 T17881 T17880 pobj brightness,for
R5330 T17882 T17881 cc and,brightness
R5331 T17883 T17881 conj contrast,brightness
R5332 T17884 T17870 punct .,transferred
R5333 T17887 T17886 prep in,Photoconverted
R5334 T17888 T17889 nummod 0.15,%
R5335 T17889 T17890 compound %,DAB
R5336 T17890 T17887 pobj DAB,in
R5337 T17891 T17892 punct (,Sigma
R5338 T17892 T17890 parataxis Sigma,DAB
R5339 T17893 T17894 nummod 3,diaminobenzidine
R5340 T17894 T17892 dep diaminobenzidine,Sigma
R5341 T17895 T17893 punct ",",3
R5342 T17896 T17893 appos 3,3
R5343 T17897 T17896 punct ′,3
R5344 T17898 T17894 punct -,diaminobenzidine
R5345 T17899 T17892 punct ;,Sigma
R5346 T17900 T17892 punct ),Sigma
R5347 T17901 T17886 prep in,Photoconverted
R5348 T17902 T17903 nummod 0.1,M
R5349 T17903 T17904 compound M,buffer
R5350 T17904 T17901 pobj buffer,in
R5351 T17905 T17904 compound Tris,buffer
R5352 T17906 T17904 punct (,buffer
R5353 T17907 T17904 npadvmod pH,buffer
R5354 T17908 T17907 nummod 8.2,pH
R5355 T17909 T17904 punct ),buffer
R5356 T17910 T17886 punct .,Photoconverted
R5357 T18468 T18469 advmod In,vitro
R5358 T18469 T18470 amod vitro,assay
R5359 T18471 T18470 compound co-culture,assay
R5360 T18472 T18470 punct .,assay
R5361 T18474 T18475 compound DRG,explants
R5362 T18475 T18476 nsubjpass explants,derived
R5363 T18477 T18476 auxpass were,derived
R5364 T18478 T18476 prep from,derived
R5365 T18479 T18480 nmod Swiss,Webster
R5366 T18480 T18481 nmod Webster,embryos
R5367 T18481 T18478 pobj embryos,from
R5368 T18482 T18480 punct ", ",Webster
R5369 T18483 T18484 npadvmod Bax,null
R5370 T18484 T18480 conj null,Webster
R5371 T18485 T18484 punct ", ",null
R5372 T18486 T18484 cc and,null
R5373 T18487 T18488 npadvmod p75,null
R5374 T18488 T18484 conj null,null
R5375 T18489 T18481 compound mouse,embryos
R5376 T18490 T18491 punct (,E13
R5377 T18491 T18481 parataxis E13,embryos
R5378 T18492 T18491 punct ),E13
R5379 T18493 T18476 punct .,derived
R5380 T18495 T18496 prep For,dissected
R5381 T18497 T18498 compound collagen,matrix
R5382 T18498 T18499 compound matrix,assays
R5383 T18499 T18495 pobj assays,For
R5384 T18500 T18496 punct ", ",dissected
R5385 T18501 T18496 nsubjpass DRGs,dissected
R5386 T18502 T18496 auxpass were,dissected
R5387 T18503 T18496 prt out,dissected
R5388 T18504 T18496 prep under,dissected
R5389 T18505 T18506 det a,stereomicroscope
R5390 T18506 T18504 pobj stereomicroscope,under
R5391 T18507 T18496 advcl using,dissected
R5392 T18508 T18509 compound tungsten,needles
R5393 T18509 T18507 dobj needles,using
R5394 T18510 T18496 punct .,dissected
R5395 T18512 T18513 compound Collagen,matrix
R5396 T18513 T18514 nsubjpass matrix,prepared
R5397 T18515 T18514 auxpass was,prepared
R5398 T18516 T18514 prep with,prepared
R5399 T18517 T18518 nummod 430,μl
R5400 T18518 T18516 pobj μl,with
R5401 T18519 T18518 prep of,μl
R5402 T18520 T18519 pobj collagen,of
R5403 T18521 T18522 punct (,Sigma
R5404 T18522 T18518 parataxis Sigma,μl
R5405 T18523 T18524 nummod 3,mg
R5406 T18524 T18522 dep mg,Sigma
R5407 T18525 T18526 punct /,ml
R5408 T18526 T18524 prep ml,mg
R5409 T18527 T18524 acl dissolved,mg
R5410 T18528 T18527 prep in,dissolved
R5411 T18529 T18530 nummod 0.1,M
R5412 T18530 T18531 nmod M,acid
R5413 T18531 T18528 pobj acid,in
R5414 T18532 T18531 amod acetic,acid
R5415 T18533 T18522 punct ", ",Sigma
R5416 T18534 T18522 punct ),Sigma
R5417 T18535 T18518 punct ", ",μl
R5418 T18536 T18537 nummod 50,μl
R5419 T18537 T18518 conj μl,μl
R5420 T18538 T18537 prep of,μl
R5421 T18539 T18540 nummod 10,DMEM
R5422 T18540 T18542 compound DMEM,medium
R5423 T18541 T18540 compound X,DMEM
R5424 T18542 T18538 pobj medium,of
R5425 T18543 T18537 punct ", ",μl
R5426 T18544 T18537 cc and,μl
R5427 T18545 T18546 nummod 2.5,μl
R5428 T18546 T18537 conj μl,μl
R5429 T18547 T18546 prep of,μl
R5430 T18548 T18549 nummod 0.8,M
R5431 T18549 T18550 compound M,NaCa2
R5432 T18550 T18547 pobj NaCa2,of
R5433 T18551 T18514 punct ", ",prepared
R5434 T18552 T18514 cc and,prepared
R5435 T18553 T18554 det the,pH
R5436 T18554 T18555 nsubjpass pH,adjusted
R5437 T18555 T18514 conj adjusted,prepared
R5438 T18556 T18555 auxpass was,adjusted
R5439 T18557 T18555 prep to,adjusted
R5440 T18558 T18557 pobj 7.5,to
R5441 T18559 T18555 punct .,adjusted
R5442 T18561 T18562 amod Individual,explants
R5443 T18562 T18564 nsubjpass explants,placed
R5444 T18563 T18562 compound ganglion,explants
R5445 T18565 T18564 auxpass were,placed
R5446 T18566 T18564 prep in,placed
R5447 T18567 T18568 nummod 24,well
R5448 T18568 T18570 compound well,plates
R5449 T18569 T18568 punct -,well
R5450 T18570 T18566 pobj plates,in
R5451 T18571 T18564 cc and,placed
R5452 T18572 T18564 conj covered,placed
R5453 T18573 T18572 prep with,covered
R5454 T18574 T18575 advmod freshly,prepared
R5455 T18575 T18576 amod prepared,collagen
R5456 T18576 T18573 pobj collagen,with
R5457 T18577 T18564 punct .,placed
R5458 T18579 T18580 compound Sepharose,beads
R5459 T18580 T18581 nsubjpass beads,used
R5460 T18582 T18580 prep with,beads
R5461 T18583 T18584 det an,diameter
R5462 T18584 T18582 pobj diameter,with
R5463 T18585 T18584 amod average,diameter
R5464 T18586 T18584 prep of,diameter
R5465 T18587 T18588 nummod 150,μm
R5466 T18588 T18586 pobj μm,of
R5467 T18589 T18581 auxpass were,used
R5468 T18590 T18581 punct .,used
R5469 T18592 T18593 nsubjpass Beads,washed
R5470 T18594 T18593 auxpass were,washed
R5471 T18595 T18593 advmod twice,washed
R5472 T18596 T18593 prep with,washed
R5473 T18597 T18596 pobj PBS,with
R5474 T18598 T18593 punct ", ",washed
R5475 T18599 T18600 dep air,dried
R5476 T18600 T18593 conj dried,washed
R5477 T18601 T18600 punct ", ",dried
R5478 T18602 T18600 cc and,dried
R5479 T18603 T18600 conj loaded,dried
R5480 T18604 T18603 prep with,loaded
R5481 T18605 T18606 nummod 10,ng
R5482 T18606 T18614 nmod ng,NT
R5483 T18607 T18605 punct ", ",10
R5484 T18608 T18605 conj 20,10
R5485 T18609 T18608 punct ", ",20
R5486 T18610 T18608 conj 50,20
R5487 T18611 T18610 punct ", ",50
R5488 T18612 T18610 cc or,50
R5489 T18613 T18610 conj 100,50
R5490 T18614 T18604 pobj NT,with
R5491 T18615 T18616 punct /,μl
R5492 T18616 T18606 prep μl,ng
R5493 T18617 T18614 punct -,NT
R5494 T18618 T18614 nummod 3,NT
R5495 T18619 T18620 punct (,Research
R5496 T18620 T18614 parataxis Research,NT
R5497 T18621 T18620 amod Collaborative,Research
R5498 T18622 T18620 punct ", ",Research
R5499 T18623 T18620 npadvmod Chemicon,Research
R5500 T18624 T18620 punct ),Research
R5501 T18625 T18603 prep at,loaded
R5502 T18626 T18627 nummod 4,°C
R5503 T18627 T18625 pobj °C,at
R5504 T18628 T18603 advmod overnight,loaded
R5505 T18629 T18603 prep with,loaded
R5506 T18630 T18631 amod constant,shaking
R5507 T18631 T18629 pobj shaking,with
R5508 T18632 T18593 punct .,washed
R5509 T18634 T18635 prep For,loaded
R5510 T18636 T18637 amod negative,control
R5511 T18637 T18634 pobj control,For
R5512 T18638 T18635 punct ", ",loaded
R5513 T18639 T18635 nsubjpass beads,loaded
R5514 T18640 T18635 auxpass were,loaded
R5515 T18641 T18635 prep with,loaded
R5516 T18642 T18641 pobj BSA,with
R5517 T18643 T18644 punct (,ng
R5518 T18644 T18642 parataxis ng,BSA
R5519 T18645 T18646 compound 10,100
R5520 T18646 T18644 nummod 100,ng
R5521 T18647 T18646 punct –,100
R5522 T18648 T18649 punct /,μl
R5523 T18649 T18644 prep μl,ng
R5524 T18650 T18644 punct ),ng
R5525 T18651 T18642 cc or,BSA
R5526 T18652 T18642 conj PBS,BSA
R5527 T18653 T18635 punct .,loaded
R5528 T18655 T18656 preconj Either,bead
R5529 T18656 T18662 nsubjpass bead,implanted
R5530 T18657 T18656 det a,bead
R5531 T18658 T18656 amod single,bead
R5532 T18659 T18660 npadvmod neurotrophin,loaded
R5533 T18660 T18656 amod loaded,bead
R5534 T18661 T18660 punct -,loaded
R5535 T18663 T18656 cc or,bead
R5536 T18664 T18665 det a,bead
R5537 T18665 T18656 conj bead,bead
R5538 T18666 T18665 amod single,bead
R5539 T18667 T18668 npadvmod BSA,loaded
R5540 T18668 T18665 amod loaded,bead
R5541 T18669 T18667 punct (,BSA
R5542 T18670 T18667 cc or,BSA
R5543 T18671 T18667 conj PBS,BSA
R5544 T18672 T18671 punct ),PBS
R5545 T18673 T18668 punct –,loaded
R5546 T18674 T18662 auxpass was,implanted
R5547 T18675 T18676 quantmod about,"1,200"
R5548 T18676 T18679 nummod "1,200",μm
R5549 T18677 T18676 compound 200,"1,200"
R5550 T18678 T18676 punct –,"1,200"
R5551 T18679 T18680 npadvmod μm,away
R5552 T18680 T18662 advmod away,implanted
R5553 T18681 T18680 prep from,away
R5554 T18682 T18683 det the,explant
R5555 T18683 T18681 pobj explant,from
R5556 T18684 T18683 compound ganglion,explant
R5557 T18685 T18662 punct .,implanted
R5558 T18687 T18688 npadvmod Collagen,embedded
R5559 T18688 T18690 amod embedded,cultures
R5560 T18689 T18688 punct -,embedded
R5561 T18690 T18691 nsubjpass cultures,placed
R5562 T18692 T18691 auxpass were,placed
R5563 T18693 T18691 advmod then,placed
R5564 T18694 T18691 prep at,placed
R5565 T18695 T18696 nummod 33,°C
R5566 T18696 T18694 pobj °C,at
R5567 T18697 T18691 prep for,placed
R5568 T18698 T18699 nummod 15,min
R5569 T18699 T18697 pobj min,for
R5570 T18700 T18701 mark for,harden
R5571 T18701 T18691 advcl harden,placed
R5572 T18702 T18703 det the,matrix
R5573 T18703 T18701 nsubj matrix,harden
R5574 T18704 T18701 aux to,harden
R5575 T18705 T18691 punct .,placed
R5576 T18707 T18708 npadvmod Serum,free
R5577 T18708 T18710 amod free,medium
R5578 T18709 T18708 punct -,free
R5579 T18710 T18712 nsubjpass medium,added
R5580 T18711 T18710 compound culture,medium
R5581 T18713 T18712 auxpass was,added
R5582 T18714 T18712 advmod then,added
R5583 T18715 T18712 prep to,added
R5584 T18716 T18717 det each,well
R5585 T18717 T18715 pobj well,to
R5586 T18718 T18712 punct .,added
R5587 T18720 T18721 prep In,added
R5588 T18722 T18720 pobj cultures,In
R5589 T18723 T18722 prep with,cultures
R5590 T18724 T18725 compound WT,DRG
R5591 T18725 T18723 pobj DRG,with
R5592 T18726 T18725 cc and,DRG
R5593 T18727 T18728 compound control,beads
R5594 T18728 T18725 conj beads,DRG
R5595 T18729 T18721 punct ", ",added
R5596 T18730 T18731 nummod 10,%
R5597 T18731 T18732 compound %,serum
R5598 T18732 T18721 nsubjpass serum,added
R5599 T18733 T18721 auxpass was,added
R5600 T18734 T18735 aux to,ensure
R5601 T18735 T18721 advcl ensure,added
R5602 T18736 T18735 dobj viability,ensure
R5603 T18737 T18736 prep of,viability
R5604 T18738 T18739 det the,explants
R5605 T18739 T18737 pobj explants,of
R5606 T18740 T18721 punct .,added
R5607 T18742 T18743 compound TrkC,Fc
R5608 T18743 T18745 nsubjpass Fc,added
R5609 T18744 T18743 punct -,Fc
R5610 T18746 T18747 punct (,Pharmaceuticals
R5611 T18747 T18743 parataxis Pharmaceuticals,Fc
R5612 T18748 T18747 compound Regeneron,Pharmaceuticals
R5613 T18749 T18747 punct ", ",Pharmaceuticals
R5614 T18750 T18747 npadvmod Tarrytown,Pharmaceuticals
R5615 T18751 T18747 punct ", ",Pharmaceuticals
R5616 T18752 T18753 compound New,York
R5617 T18753 T18747 npadvmod York,Pharmaceuticals
R5618 T18754 T18747 punct ", ",Pharmaceuticals
R5619 T18755 T18756 compound United,States
R5620 T18756 T18747 npadvmod States,Pharmaceuticals
R5621 T18757 T18747 punct ),Pharmaceuticals
R5622 T18758 T18745 auxpass was,added
R5623 T18759 T18760 punct (,μg
R5624 T18760 T18745 parataxis μg,added
R5625 T18761 T18760 nummod 20,μg
R5626 T18762 T18763 punct /,ml
R5627 T18763 T18760 prep ml,μg
R5628 T18764 T18760 punct ),μg
R5629 T18765 T18745 prep into,added
R5630 T18766 T18767 det the,medium
R5631 T18767 T18765 pobj medium,into
R5632 T18768 T18767 compound culture,medium
R5633 T18769 T18745 punct .,added
R5634 T19117 T19118 compound Explant,co-cultures
R5635 T19120 T19121 amod Spinal,cords
R5636 T19121 T19122 nsubjpass cords,dissected
R5637 T19123 T19121 prep with,cords
R5638 T19124 T19125 amod attached,DRGs
R5639 T19125 T19123 pobj DRGs,with
R5640 T19126 T19122 auxpass were,dissected
R5641 T19127 T19122 prt out,dissected
R5642 T19128 T19122 prep from,dissected
R5643 T19129 T19130 compound Swiss,Webster
R5644 T19130 T19131 compound Webster,embryos
R5645 T19131 T19128 pobj embryos,from
R5646 T19132 T19131 compound mouse,embryos
R5647 T19133 T19131 prep at,embryos
R5648 T19134 T19133 pobj E13,at
R5649 T19135 T19122 punct ", ",dissected
R5650 T19136 T19122 cc and,dissected
R5651 T19137 T19122 conj sectioned,dissected
R5652 T19138 T19137 prep into,sectioned
R5653 T19139 T19140 nummod 300,μm
R5654 T19140 T19142 npadvmod μm,thick
R5655 T19141 T19140 punct -,μm
R5656 T19142 T19144 amod thick,slices
R5657 T19143 T19142 punct -,thick
R5658 T19144 T19138 pobj slices,into
R5659 T19145 T19122 punct .,dissected
R5660 T19147 T19148 compound Tissue,slices
R5661 T19148 T19149 nsubjpass slices,placed
R5662 T19150 T19149 auxpass were,placed
R5663 T19151 T19149 prep on,placed
R5664 T19152 T19153 compound Millicell,Inserts
R5665 T19153 T19151 pobj Inserts,on
R5666 T19154 T19155 compound Tissue,Culture
R5667 T19155 T19153 compound Culture,Inserts
R5668 T19156 T19157 punct (,Millipore
R5669 T19157 T19153 parataxis Millipore,Inserts
R5670 T19158 T19157 punct ", ",Millipore
R5671 T19159 T19157 npadvmod Billrica,Millipore
R5672 T19160 T19157 punct ", ",Millipore
R5673 T19161 T19157 npadvmod Massachusetts,Millipore
R5674 T19162 T19157 punct ", ",Millipore
R5675 T19163 T19164 compound United,States
R5676 T19164 T19157 npadvmod States,Millipore
R5677 T19165 T19157 punct ),Millipore
R5678 T19166 T19149 punct .,placed
R5679 T19168 T19169 npadvmod NT,loaded
R5680 T19169 T19173 amod loaded,beads
R5681 T19170 T19168 punct -,NT
R5682 T19171 T19168 nummod 3,NT
R5683 T19172 T19169 punct -,loaded
R5684 T19173 T19189 nsubjpass beads,prepared
R5685 T19174 T19175 punct (,15
R5686 T19175 T19169 parataxis 15,loaded
R5687 T19176 T19175 nsubj n,15
R5688 T19177 T19175 punct =,15
R5689 T19178 T19175 punct ),15
R5690 T19179 T19169 cc or,loaded
R5691 T19180 T19181 npadvmod PBS,loaded
R5692 T19181 T19169 conj loaded,loaded
R5693 T19182 T19181 punct -,loaded
R5694 T19183 T19184 punct (,6
R5695 T19184 T19181 parataxis 6,loaded
R5696 T19185 T19184 nsubj n,6
R5697 T19186 T19184 punct =,6
R5698 T19187 T19184 punct ),6
R5699 T19188 T19173 compound sepharose,beads
R5700 T19190 T19189 auxpass were,prepared
R5701 T19191 T19192 mark as,described
R5702 T19192 T19189 advcl described,prepared
R5703 T19193 T19192 advmod above,described
R5704 T19194 T19189 punct ", ",prepared
R5705 T19195 T19189 cc and,prepared
R5706 T19196 T19189 conj placed,prepared
R5707 T19197 T19196 prep in,placed
R5708 T19198 T19199 det the,midline
R5709 T19199 T19197 pobj midline,in
R5710 T19200 T19196 prep at,placed
R5711 T19201 T19202 amod mid-spinal,cord
R5712 T19202 T19203 compound cord,level
R5713 T19203 T19200 pobj level,at
R5714 T19204 T19189 punct .,prepared
R5715 T19206 T19207 nsubjpass Inserts,placed
R5716 T19208 T19207 auxpass were,placed
R5717 T19209 T19207 prep in,placed
R5718 T19210 T19211 nummod six,well
R5719 T19211 T19213 compound well,plates
R5720 T19212 T19211 punct -,well
R5721 T19213 T19209 pobj plates,in
R5722 T19214 T19207 prep with,placed
R5723 T19215 T19216 npadvmod serum,free
R5724 T19216 T19218 amod free,medium
R5725 T19217 T19216 punct -,free
R5726 T19218 T19214 pobj medium,with
R5727 T19219 T19218 prep at,medium
R5728 T19220 T19221 det the,bottom
R5729 T19221 T19219 pobj bottom,at
R5730 T19222 T19221 prep of,bottom
R5731 T19223 T19224 det the,wells
R5732 T19224 T19222 pobj wells,of
R5733 T19225 T19207 punct ", ",placed
R5734 T19226 T19207 cc and,placed
R5735 T19227 T19207 conj kept,placed
R5736 T19228 T19227 prep at,kept
R5737 T19229 T19230 nummod 33,°C
R5738 T19230 T19228 pobj °C,at
R5739 T19231 T19227 prep for,kept
R5740 T19232 T19233 nummod 3,d
R5741 T19233 T19231 pobj d,for
R5742 T19234 T19227 prep in,kept
R5743 T19235 T19236 det the,presence
R5744 T19236 T19234 pobj presence,in
R5745 T19237 T19236 prep of,presence
R5746 T19238 T19239 nummod 5,%
R5747 T19239 T19240 compound %,CO2
R5748 T19240 T19237 pobj CO2,of
R5749 T19241 T19207 punct .,placed
R5750 T19243 T19244 nsubjpass Cultures,fixed
R5751 T19245 T19244 auxpass were,fixed
R5752 T19246 T19244 advmod then,fixed
R5753 T19247 T19244 prep with,fixed
R5754 T19248 T19249 nummod 4,%
R5755 T19249 T19250 compound %,paraformaldehyde
R5756 T19250 T19247 pobj paraformaldehyde,with
R5757 T19251 T19244 prep in,fixed
R5758 T19252 T19251 pobj PBS,in
R5759 T19253 T19244 punct ", ",fixed
R5760 T19254 T19244 cc and,fixed
R5761 T19255 T19256 amod small,crystals
R5762 T19256 T19257 nsubjpass crystals,placed
R5763 T19257 T19244 conj placed,fixed
R5764 T19258 T19256 prep of,crystals
R5765 T19259 T19258 pobj DiI,of
R5766 T19260 T19257 auxpass were,placed
R5767 T19261 T19257 prep into,placed
R5768 T19262 T19263 det the,DRGs
R5769 T19263 T19261 pobj DRGs,into
R5770 T19264 T19257 punct .,placed
R5771 T19266 T19267 nsubjpass Samples,incubated
R5772 T19268 T19267 auxpass were,incubated
R5773 T19269 T19267 prep in,incubated
R5774 T19270 T19271 det a,incubator
R5775 T19271 T19269 pobj incubator,in
R5776 T19272 T19273 nummod 37,°C
R5777 T19273 T19271 compound °C,incubator
R5778 T19274 T19273 punct -,°C
R5779 T19275 T19267 punct ", ",incubated
R5780 T19276 T19267 advcl allowing,incubated
R5781 T19277 T19278 det the,dye
R5782 T19278 T19279 nsubj dye,diffuse
R5783 T19279 T19276 ccomp diffuse,allowing
R5784 T19280 T19279 aux to,diffuse
R5785 T19281 T19267 punct ", ",incubated
R5786 T19282 T19267 cc and,incubated
R5787 T19283 T19267 conj photographed,incubated
R5788 T19284 T19283 prep under,photographed
R5789 T19285 T19286 det a,microscope
R5790 T19286 T19284 pobj microscope,under
R5791 T19287 T19286 nmod Nikon,microscope
R5792 T19288 T19289 punct (,Tokyo
R5793 T19289 T19287 parataxis Tokyo,Nikon
R5794 T19290 T19289 punct ", ",Tokyo
R5795 T19291 T19289 npadvmod Japan,Tokyo
R5796 T19292 T19289 punct ),Tokyo
R5797 T19293 T19294 amod inverted,epifluoresence
R5798 T19294 T19286 compound epifluoresence,microscope
R5799 T19295 T19267 punct .,incubated
R95 T512 T502 conj enter,are
R202 T1221 T1216 appos receptor,NT
R287 T1308 T1306 pobj cord,in
R293 T1314 T1312 pobj buds,in
R326 T1348 T1351 advcl contact,induce
R341 T1364 T1360 dobj endings,forming
R415 T1442 T1440 pobj arc,of
R479 T2363 T2366 ccomp require,used
R508 T2395 T2393 dobj heterozygote,bred
R598 T2491 T2489 pobj KOs,in
R654 T2551 T2554 compound KO,animals
R696 T2595 T2598 amod immunopositive,cells
R741 T2642 T2645 amod null,DRGs
R774 T2677 T2675 pobj marker,of
R1215 T4427 T4424 pobj KOs,In
R2870 T13747 T13745 pobj promoter,by
R3042 T13925 T13923 ccomp is,appears
R3221 T14127 T14120 aux has,noted
R3222 T14128 T14120 auxpass been,noted
R3224 T14130 T14131 mark that,are
R3599 T14523 T14486 punct .,reported
R3706 T14640 T14635 amod double,KO
R3968 T14914 T14913 neg not,is
R3969 T14915 T14913 acomp definitive,is
R3970 T14916 T14917 mark that,expressed
R4325 T15292 T15293 nsubj Slit2,cause

2_test

Id Subject Object Predicate Lexical cue
15550985-7991545-84929433 6380-6384 7991545 denotes 1994
15550985-3902852-84929434 9848-9852 3902852 denotes 1985
15550985-10448156-84929414 1221-1225 10448156 denotes 1999
15550985-12593987-84929415 1239-1243 12593987 denotes 2003
15550985-7514502-84929416 1535-1539 7514502 denotes 1994
15550985-8145824-84929417 1554-1558 8145824 denotes 1994
15550985-7991545-84929418 1578-1582 7991545 denotes 1994
15550985-8982156-84929419 1599-1603 8982156 denotes 1996
15550985-9364058-84929420 1618-1622 9364058 denotes 1997
15550985-12352981-84929421 1637-1641 12352981 denotes 2002
15550985-12093746-84929422 1658-1662 12093746 denotes 2002
15550985-8982156-84929423 1850-1854 8982156 denotes 1996
15550985-8834404-84929424 1868-1872 8834404 denotes 1996
15550985-7789265-84929425 2208-2212 7789265 denotes 1995
15550985-9151743-84929426 2214-2218 9151743 denotes 1997
15550985-9454852-84929427 2850-2854 9454852 denotes 1998
15550985-10719890-84929428 2869-2873 10719890 denotes 2000
15550985-7991545-84929429 3156-3160 7991545 denotes 1994
15550985-10207144-84929430 3228-3232 10207144 denotes 1999
15550985-9100133-84929431 5406-5410 9100133 denotes 1997
15550985-7514502-84929432 6356-6360 7514502 denotes 1994
15550985-7514502-84929435 9941-9945 7514502 denotes 1994
15550985-9331344-84929436 10108-10112 9331344 denotes 1997
15550985-3762707-84929437 18528-18532 3762707 denotes 1986
15550985-10677035-84929438 18622-18626 10677035 denotes 1999
15550985-11135642-84929439 18654-18658 11135642 denotes 2001
15550985-9217002-84929440 19242-19246 9217002 denotes 1997
15550985-7789265-84929441 19585-19589 7789265 denotes 1995
15550985-7789265-84929442 19832-19836 7789265 denotes 1995
15550985-9217002-84929443 19857-19861 9217002 denotes 1997
15550985-9822165-84929444 20542-20546 9822165 denotes 1998
15550985-10583476-84929445 20564-20568 10583476 denotes 1999
15550985-10082829-84929446 20584-20588 10082829 denotes 1999
15550985-11860276-84929447 20603-20607 11860276 denotes 2002
15550985-12598631-84929448 20704-20708 12598631 denotes 2003
15550985-9331344-84929449 21132-21136 9331344 denotes 1997
15550985-10448156-84929450 21518-21522 10448156 denotes 1999
15550985-12741988-84929451 21654-21658 12741988 denotes 2003
15550985-9217002-84929452 22375-22379 9217002 denotes 1997
15550985-10719890-84929453 22394-22398 10719890 denotes 2000
15550985-7514427-84929454 22740-22744 7514427 denotes 1994
15550985-12741988-84929455 23318-23322 12741988 denotes 2003
15550985-12741988-84929456 24417-24421 12741988 denotes 2003
15550985-12741988-84929457 24632-24636 12741988 denotes 2003
15550985-12741988-84929458 25347-25351 12741988 denotes 2003
15550985-11395002-84929459 25988-25992 11395002 denotes 2001
15550985-11988168-84929460 26005-26009 11988168 denotes 2002
15550985-8032912-84929461 26324-26328 8032912 denotes 1994
15550985-10213469-84929462 26345-26349 10213469 denotes 1999
15550985-10602090-84929463 26363-26367 10602090 denotes 2000
15550985-9217002-84929464 26511-26515 9217002 denotes 1997
15550985-9217002-84929465 26990-26994 9217002 denotes 1997
15550985-11135642-84929466 27010-27014 11135642 denotes 2001
15550985-10954840-84929467 27379-27383 10954840 denotes 2000
15550985-11559894-84929468 27408-27412 11559894 denotes 2001
15550985-12354395-84929469 27581-27585 12354395 denotes 2002
15550985-10102266-84929470 27672-27676 10102266 denotes 1999
15550985-11404413-84929471 27744-27748 11404413 denotes 2001
15550985-12040061-84929472 27773-27777 12040061 denotes 2002
15550985-10102266-84929473 27927-27931 10102266 denotes 1999
15550985-11404413-84929474 28029-28033 11404413 denotes 2001
15550985-12040061-84929475 28143-28147 12040061 denotes 2002
15550985-9950767-84929476 28769-28773 9950767 denotes 1999
15550985-10207144-84929477 31200-31204 10207144 denotes 1999
T22118 1221-1225 10448156 denotes 1999
T49168 1239-1243 12593987 denotes 2003
T95946 1535-1539 7514502 denotes 1994
T87502 1554-1558 8145824 denotes 1994
T43163 1578-1582 7991545 denotes 1994
T14955 1599-1603 8982156 denotes 1996
T85814 1618-1622 9364058 denotes 1997
T98231 1637-1641 12352981 denotes 2002
T68047 1658-1662 12093746 denotes 2002
T4730 1850-1854 8982156 denotes 1996
T12331 1868-1872 8834404 denotes 1996
T55774 2208-2212 7789265 denotes 1995
T805 2214-2218 9151743 denotes 1997
T52362 2850-2854 9454852 denotes 1998
T83346 2869-2873 10719890 denotes 2000
T6809 3156-3160 7991545 denotes 1994
T58749 3228-3232 10207144 denotes 1999
T20136 5406-5410 9100133 denotes 1997
T48100 6356-6360 7514502 denotes 1994
T88681 6380-6384 7991545 denotes 1994
T37682 9848-9852 3902852 denotes 1985
T57993 9941-9945 7514502 denotes 1994
T5248 10108-10112 9331344 denotes 1997
T85777 18528-18532 3762707 denotes 1986
T74000 18622-18626 10677035 denotes 1999
T54626 18654-18658 11135642 denotes 2001
T54981 19242-19246 9217002 denotes 1997
T19681 19585-19589 7789265 denotes 1995
T23136 19832-19836 7789265 denotes 1995
T54863 19857-19861 9217002 denotes 1997
T40743 20542-20546 9822165 denotes 1998
T46942 20564-20568 10583476 denotes 1999
T18741 20584-20588 10082829 denotes 1999
T82518 20603-20607 11860276 denotes 2002
T21645 20704-20708 12598631 denotes 2003
T30257 21132-21136 9331344 denotes 1997
T61237 21518-21522 10448156 denotes 1999
T33718 21654-21658 12741988 denotes 2003
T17318 22375-22379 9217002 denotes 1997
T54115 22394-22398 10719890 denotes 2000
T57414 22740-22744 7514427 denotes 1994
T79188 23318-23322 12741988 denotes 2003
T55770 24417-24421 12741988 denotes 2003
T58025 24632-24636 12741988 denotes 2003
T86483 25347-25351 12741988 denotes 2003
T90002 25988-25992 11395002 denotes 2001
T65300 26005-26009 11988168 denotes 2002
T39998 26324-26328 8032912 denotes 1994
T31818 26345-26349 10213469 denotes 1999
T15189 26363-26367 10602090 denotes 2000
T92402 26511-26515 9217002 denotes 1997
T16881 26990-26994 9217002 denotes 1997
T54426 27010-27014 11135642 denotes 2001
T62789 27379-27383 10954840 denotes 2000
T57909 27408-27412 11559894 denotes 2001
T90791 27581-27585 12354395 denotes 2002
T68099 27672-27676 10102266 denotes 1999
T48384 27744-27748 11404413 denotes 2001
T67931 27773-27777 12040061 denotes 2002
T16246 27927-27931 10102266 denotes 1999
T40995 28029-28033 11404413 denotes 2001
T57729 28143-28147 12040061 denotes 2002
T57842 28769-28773 9950767 denotes 1999
T84153 31200-31204 10207144 denotes 1999