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PMC:523229 / 7038-8470 JSONTXT

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craft-sa-dev

Id Subject Object Predicate Lexical cue
T1953 0-1 DT denotes A
T1954 10-16 NN denotes system
T1955 2-9 JJ denotes genetic
T1956 90-92 VB denotes be
T1957 17-20 IN denotes for
T1958 21-31 VBG denotes activating
T1959 32-34 CC denotes or
T1960 35-47 VBG denotes inactivating
T1961 48-53 NNS denotes genes
T1962 54-66 RB denotes specifically
T1963 67-69 IN denotes in
T1964 70-75 NN denotes joint
T1965 76-83 NNS denotes tissues
T1966 84-89 MD denotes would
T1967 93-105 RB denotes particularly
T1968 106-112 JJ denotes useful
T1969 113-116 IN denotes for
T1970 117-124 JJ denotes further
T1971 125-132 NNS denotes studies
T1972 133-135 IN denotes of
T1973 136-141 NN denotes joint
T1974 142-151 NN denotes formation
T1975 152-155 CC denotes and
T1976 156-167 NN denotes maintenance
T1977 167-168 . denotes .
T1978 168-370 sentence denotes Here we take advantage of the tissue-specific expression pattern of the Gdf5 gene to engineer a Cre/loxP system (Nagy 2000), Gdf5-Cre, that can be used to remove or ectopically express genes in joints.
T1979 169-173 RB denotes Here
T1980 177-181 VBP denotes take
T1981 174-176 PRP denotes we
T1982 182-191 NN denotes advantage
T1983 192-194 IN denotes of
T1984 195-198 DT denotes the
T1985 226-233 NN denotes pattern
T1986 199-205 NN denotes tissue
T1987 206-214 JJ denotes specific
T1988 205-206 HYPH denotes -
T1989 215-225 NN denotes expression
T1990 234-236 IN denotes of
T1991 237-240 DT denotes the
T1992 246-250 NN denotes gene
T1993 241-245 NN denotes Gdf5
T1994 251-253 TO denotes to
T1995 254-262 VB denotes engineer
T1996 263-264 DT denotes a
T1997 274-280 NN denotes system
T1998 265-268 NN denotes Cre
T1999 269-273 NN denotes loxP
T2000 268-269 HYPH denotes /
T2001 281-282 -LRB- denotes (
T2002 282-286 NNP denotes Nagy
T2003 287-291 CD denotes 2000
T2004 291-292 -RRB- denotes )
T2005 292-294 , denotes ,
T2006 294-298 NN denotes Gdf5
T2007 299-302 NN denotes Cre
T2008 298-299 HYPH denotes -
T2009 302-304 , denotes ,
T2010 304-308 WDT denotes that
T2011 316-320 VBN denotes used
T2012 309-312 MD denotes can
T2013 313-315 VB denotes be
T2014 321-323 TO denotes to
T2015 324-330 VB denotes remove
T2016 331-333 CC denotes or
T2017 334-345 RB denotes ectopically
T2018 346-353 VB denotes express
T2019 354-359 NNS denotes genes
T2020 360-362 IN denotes in
T2021 363-369 NNS denotes joints
T2022 369-370 . denotes .
T2023 370-600 sentence denotes Tests with reporter mice show that this system is capable of modifying genes in all of the structures of the mature synovial joint, including the ligaments of the joint capsule, the synovial membrane, and the articular cartilage.
T2024 371-376 NNS denotes Tests
T2025 396-400 VBP denotes show
T2026 377-381 IN denotes with
T2027 382-390 NN denotes reporter
T2028 391-395 NNS denotes mice
T2029 401-405 IN denotes that
T2030 418-420 VBZ denotes is
T2031 406-410 DT denotes this
T2032 411-417 NN denotes system
T2033 421-428 JJ denotes capable
T2034 429-431 IN denotes of
T2035 432-441 VBG denotes modifying
T2036 442-447 NNS denotes genes
T2037 448-450 IN denotes in
T2038 451-454 DT denotes all
T2039 455-457 IN denotes of
T2040 458-461 DT denotes the
T2041 462-472 NNS denotes structures
T2042 473-475 IN denotes of
T2043 476-479 DT denotes the
T2044 496-501 NN denotes joint
T2045 480-486 JJ denotes mature
T2046 487-495 JJ denotes synovial
T2047 501-503 , denotes ,
T2048 503-512 VBG denotes including
T2049 513-516 DT denotes the
T2050 517-526 NNS denotes ligaments
T2051 527-529 IN denotes of
T2052 530-533 DT denotes the
T2053 540-547 NN denotes capsule
T2054 534-539 NN denotes joint
T2055 547-549 , denotes ,
T2056 549-552 DT denotes the
T2057 562-570 NN denotes membrane
T2058 553-561 JJ denotes synovial
T2059 570-572 , denotes ,
T2060 572-575 CC denotes and
T2061 576-579 DT denotes the
T2062 590-599 NN denotes cartilage
T2063 580-589 JJ denotes articular
T2064 599-600 . denotes .
T2065 600-847 sentence denotes Gdf5-Cre recombination bypasses the early embryonic lethality of null mutations in Bmpr1a, and shows that this receptor is required for early joint formation at some locations and for initiation of programmed cell death in webbing between digits.
T2066 601-605 NN denotes Gdf5
T2067 606-609 NN denotes Cre
T2068 605-606 HYPH denotes -
T2069 610-623 NN denotes recombination
T2070 624-632 VBZ denotes bypasses
T2071 633-636 DT denotes the
T2072 653-662 NN denotes lethality
T2073 637-642 JJ denotes early
T2074 643-652 JJ denotes embryonic
T2075 663-665 IN denotes of
T2076 666-670 JJ denotes null
T2077 671-680 NNS denotes mutations
T2078 681-683 IN denotes in
T2079 684-690 NN denotes Bmpr1a
T2080 690-692 , denotes ,
T2081 692-695 CC denotes and
T2082 696-701 VBZ denotes shows
T2083 702-706 IN denotes that
T2084 724-732 VBN denotes required
T2085 707-711 DT denotes this
T2086 712-720 NN denotes receptor
T2087 721-723 VBZ denotes is
T2088 733-736 IN denotes for
T2089 737-742 JJ denotes early
T2090 749-758 NN denotes formation
T2091 743-748 NN denotes joint
T2092 759-761 IN denotes at
T2093 762-766 DT denotes some
T2094 767-776 NNS denotes locations
T2095 777-780 CC denotes and
T2096 781-784 IN denotes for
T2097 785-795 NN denotes initiation
T2098 796-798 IN denotes of
T2099 799-809 VBN denotes programmed
T2100 815-820 NN denotes death
T2101 810-814 NN denotes cell
T2102 821-823 IN denotes in
T2103 824-831 VBG denotes webbing
T2104 832-839 IN denotes between
T2105 840-846 NNS denotes digits
T2106 846-847 . denotes .
T2107 847-968 sentence denotes Interestingly, Bmpr1a is also required for postnatal maintenance of articular cartilage throughout most of the skeleton.
T2108 848-861 RB denotes Interestingly
T2109 870-872 VBZ denotes is
T2110 861-863 , denotes ,
T2111 863-869 NN denotes Bmpr1a
T2112 873-877 RB denotes also
T2113 878-886 VBN denotes required
T2114 887-890 IN denotes for
T2115 891-900 JJ denotes postnatal
T2116 901-912 NN denotes maintenance
T2117 913-915 IN denotes of
T2118 916-925 JJ denotes articular
T2119 926-935 NN denotes cartilage
T2120 936-946 IN denotes throughout
T2121 947-951 JJS denotes most
T2122 952-954 IN denotes of
T2123 955-958 DT denotes the
T2124 959-967 NN denotes skeleton
T2125 967-968 . denotes .
T2126 968-1124 sentence denotes In Gdf5-Cre/Bmpr1afloxP mice, articular cartilage initially forms normally, but subsequently loses expression of several key cartilage markers after birth.
T2127 969-971 IN denotes In
T2128 1029-1034 VBZ denotes forms
T2129 972-976 NN denotes Gdf5
T2130 977-980 NN denotes Cre
T2131 976-977 HYPH denotes -
T2132 993-997 NNS denotes mice
T2133 980-981 HYPH denotes /
T2134 981-992 NN denotes Bmpr1afloxP
T2135 997-999 , denotes ,
T2136 999-1008 JJ denotes articular
T2137 1009-1018 NN denotes cartilage
T2138 1019-1028 RB denotes initially
T2139 1035-1043 RB denotes normally
T2140 1043-1045 , denotes ,
T2141 1045-1048 CC denotes but
T2142 1049-1061 RB denotes subsequently
T2143 1062-1067 VBZ denotes loses
T2144 1068-1078 NN denotes expression
T2145 1079-1081 IN denotes of
T2146 1082-1089 JJ denotes several
T2147 1104-1111 NNS denotes markers
T2148 1090-1093 JJ denotes key
T2149 1094-1103 NN denotes cartilage
T2150 1112-1117 IN denotes after
T2151 1118-1123 NN denotes birth
T2152 1123-1124 . denotes .
T2153 1124-1224 sentence denotes It ultimately fibrillates and degenerates, resulting in severe osteoarthritis and loss of mobility.
T2154 1125-1127 PRP denotes It
T2155 1139-1150 VBZ denotes fibrillates
T2156 1128-1138 RB denotes ultimately
T2157 1151-1154 CC denotes and
T2158 1155-1166 VBZ denotes degenerates
T2159 1166-1168 , denotes ,
T2160 1168-1177 VBG denotes resulting
T2161 1178-1180 IN denotes in
T2162 1181-1187 JJ denotes severe
T2163 1188-1202 NN denotes osteoarthritis
T2164 1203-1206 CC denotes and
T2165 1207-1211 NN denotes loss
T2166 1212-1214 IN denotes of
T2167 1215-1223 NN denotes mobility
T2168 1223-1224 . denotes .
T2169 1224-1432 sentence denotes These experiments suggest that BMP signaling is required for normal maintenance of postnatal articular cartilage, and that modulation of the BMP signaling pathway may play an important role in joint disease.
T2170 1225-1230 DT denotes These
T2171 1231-1242 NNS denotes experiments
T2172 1243-1250 VBP denotes suggest
T2173 1251-1255 IN denotes that
T2174 1273-1281 VBN denotes required
T2175 1256-1259 NN denotes BMP
T2176 1260-1269 NN denotes signaling
T2177 1270-1272 VBZ denotes is
T2178 1282-1285 IN denotes for
T2179 1286-1292 JJ denotes normal
T2180 1293-1304 NN denotes maintenance
T2181 1305-1307 IN denotes of
T2182 1308-1317 JJ denotes postnatal
T2183 1328-1337 NN denotes cartilage
T2184 1318-1327 JJ denotes articular
T2185 1337-1339 , denotes ,
T2186 1339-1342 CC denotes and
T2187 1343-1347 IN denotes that
T2188 1392-1396 VB denotes play
T2189 1348-1358 NN denotes modulation
T2190 1359-1361 IN denotes of
T2191 1362-1365 DT denotes the
T2192 1380-1387 NN denotes pathway
T2193 1366-1369 NN denotes BMP
T2194 1370-1379 NN denotes signaling
T2195 1388-1391 MD denotes may
T2196 1397-1399 DT denotes an
T2197 1410-1414 NN denotes role
T2198 1400-1409 JJ denotes important
T2199 1415-1417 IN denotes in
T2200 1418-1423 NN denotes joint
T2201 1424-1431 NN denotes disease
T2202 1431-1432 . denotes .
R1140 T2014 T2015 aux to,remove
R1141 T2015 T2011 advcl remove,used
R1143 T2016 T2015 cc or,remove
R1144 T2017 T2018 advmod ectopically,express
R1145 T2018 T2015 conj express,remove
R1147 T2019 T2018 dobj genes,express
R1148 T2020 T2019 prep in,genes
R1150 T2021 T2020 pobj joints,in
R1151 T2022 T1980 punct .,take
R1153 T2024 T2025 nsubj Tests,show
R1155 T2026 T2024 prep with,Tests
R1156 T2027 T2028 compound reporter,mice
R1157 T2028 T2026 pobj mice,with
R1159 T2029 T2030 mark that,is
R1160 T2030 T2025 ccomp is,show
R1161 T2031 T2032 det this,system
R1163 T2032 T2030 nsubj system,is
R1164 T2033 T2030 acomp capable,is
R1165 T2034 T2033 prep of,capable
R1166 T2035 T2034 pcomp modifying,of
R1167 T2036 T2035 dobj genes,modifying
R1169 T2037 T2035 prep in,modifying
R1170 T2038 T2037 pobj all,in
R1172 T2039 T2038 prep of,all
R1173 T2040 T2041 det the,structures
R1174 T2041 T2039 pobj structures,of
R1176 T2042 T2041 prep of,structures
R1177 T2043 T2044 det the,joint
R1178 T2044 T2042 pobj joint,of
R1180 T2045 T2044 amod mature,joint
R1181 T2046 T2044 amod synovial,joint
R1183 T2047 T2038 punct ", ",all
R1185 T2048 T2038 prep including,all
R1187 T2049 T2050 det the,ligaments
R1188 T2050 T2048 pobj ligaments,including
R1189 T2051 T2050 prep of,ligaments
R1190 T2052 T2053 det the,capsule
R1193 T2053 T2051 pobj capsule,of
R1194 T2054 T2053 compound joint,capsule
R1196 T2055 T2050 punct ", ",ligaments
R1197 T2056 T2057 det the,membrane
R1199 T2057 T2050 conj membrane,ligaments
R1200 T2058 T2057 amod synovial,membrane
R1202 T2059 T2057 punct ", ",membrane
R1203 T2060 T2057 cc and,membrane
R1204 T2061 T2062 det the,cartilage
R1206 T2062 T2057 conj cartilage,membrane
R1207 T2063 T2062 amod articular,cartilage
R1209 T2064 T2025 punct .,show
R1210 T2066 T2067 compound Gdf5,Cre
R1212 T2067 T2069 compound Cre,recombination
R1213 T2068 T2067 punct -,Cre
R1214 T2069 T2070 nsubj recombination,bypasses
R1216 T2071 T2072 det the,lethality
R1218 T2072 T2070 dobj lethality,bypasses
R1219 T2073 T2074 amod early,embryonic
R1220 T2074 T2072 amod embryonic,lethality
R1222 T2075 T2072 prep of,lethality
R1223 T2076 T2077 amod null,mutations
R1225 T2077 T2075 pobj mutations,of
R1226 T2078 T2070 prep in,bypasses
R1227 T2079 T2078 pobj Bmpr1a,in
R1229 T2080 T2070 punct ", ",bypasses
R1230 T2081 T2070 cc and,bypasses
R1231 T2082 T2070 conj shows,bypasses
R1233 T2083 T2084 mark that,required
R1234 T2084 T2082 ccomp required,shows
R1236 T2085 T2086 det this,receptor
R1237 T2086 T2084 nsubjpass receptor,required
R1238 T2087 T2084 auxpass is,required
R1240 T2088 T2084 prep for,required
R1241 T2089 T2090 amod early,formation
R1242 T2090 T2088 pobj formation,for
R1243 T2091 T2090 compound joint,formation
R1244 T2092 T2090 prep at,formation
R1245 T2093 T2094 det some,locations
R1247 T2094 T2092 pobj locations,at
R1248 T2095 T2088 cc and,for
R1249 T2096 T2088 conj for,for
R1251 T2097 T2096 pobj initiation,for
R1252 T2098 T2097 prep of,initiation
R1253 T2099 T2100 amod programmed,death
R1254 T2100 T2098 pobj death,of
R1256 T2101 T2100 compound cell,death
R1257 T2102 T2100 prep in,death
R1259 T2103 T2102 pobj webbing,in
R1261 T2104 T2103 prep between,webbing
R1262 T2105 T2104 pobj digits,between
R1263 T2106 T2070 punct .,bypasses
R1265 T2108 T2109 advmod Interestingly,is
R1267 T2110 T2109 punct ", ",is
R1268 T2111 T2109 nsubj Bmpr1a,is
R1269 T2112 T2109 advmod also,is
R1271 T2113 T2109 acomp required,is
R1272 T2114 T2109 prep for,is
R1273 T2115 T2116 amod postnatal,maintenance
R1274 T1953 T1954 det A,system
R1275 T2116 T2114 pobj maintenance,for
R1276 T2117 T2116 prep of,maintenance
R1277 T2118 T2119 amod articular,cartilage
R1278 T2119 T2117 pobj cartilage,of
R1279 T1954 T1956 nsubj system,be
R1280 T2120 T2109 prep throughout,is
R1281 T1955 T1954 amod genetic,system
R1282 T1957 T1954 prep for,system
R1283 T2121 T2120 pobj most,throughout
R1284 T1958 T1957 pcomp activating,for
R1285 T2122 T2121 prep of,most
R1286 T2123 T2124 det the,skeleton
R1287 T2124 T2122 pobj skeleton,of
R1288 T1959 T1958 cc or,activating
R1289 T2125 T2109 punct .,is
R1290 T2127 T2128 prep In,forms
R1291 T1960 T1958 conj inactivating,activating
R1292 T2129 T2130 nmod Gdf5,Cre
R1293 T2130 T2132 nmod Cre,mice
R1294 T2131 T2130 punct -,Cre
R1295 T2132 T2127 pobj mice,In
R1296 T2133 T2130 punct /,Cre
R1297 T1961 T1960 dobj genes,inactivating
R1298 T2134 T2130 appos Bmpr1afloxP,Cre
R1299 T1962 T1963 advmod specifically,in
R1300 T2135 T2128 punct ", ",forms
R1301 T2136 T2137 amod articular,cartilage
R1302 T1963 T1960 prep in,inactivating
R1303 T2137 T2128 nsubj cartilage,forms
R1304 T2138 T2128 advmod initially,forms
R1305 T2139 T2128 advmod normally,forms
R1306 T1964 T1965 compound joint,tissues
R1307 T2140 T2128 punct ", ",forms
R1308 T2141 T2128 cc but,forms
R1309 T1965 T1963 pobj tissues,in
R1310 T2142 T2143 advmod subsequently,loses
R1311 T2143 T2128 conj loses,forms
R1312 T1966 T1956 aux would,be
R1313 T2144 T2143 dobj expression,loses
R1314 T2145 T2144 prep of,expression
R1315 T2146 T2147 amod several,markers
R1316 T1967 T1968 advmod particularly,useful
R1317 T2147 T2145 pobj markers,of
R1318 T2148 T2147 amod key,markers
R1319 T1968 T1956 acomp useful,be
R1320 T2149 T2147 compound cartilage,markers
R1321 T2150 T2143 prep after,loses
R1322 T2151 T2150 pobj birth,after
R1323 T1969 T1968 prep for,useful
R1324 T2152 T2128 punct .,forms
R1325 T1970 T1971 amod further,studies
R1326 T2154 T2155 nsubj It,fibrillates
R1327 T1971 T1969 pobj studies,for
R1328 T2156 T2155 advmod ultimately,fibrillates
R1329 T2157 T2155 cc and,fibrillates
R1330 T2158 T2155 conj degenerates,fibrillates
R1331 T1972 T1971 prep of,studies
R1332 T2159 T2158 punct ", ",degenerates
R1333 T2160 T2158 conj resulting,degenerates
R1334 T2161 T2160 prep in,resulting
R1335 T1973 T1974 compound joint,formation
R1336 T2162 T2163 amod severe,osteoarthritis
R1337 T2163 T2161 pobj osteoarthritis,in
R1338 T2164 T2163 cc and,osteoarthritis
R1339 T1974 T1972 pobj formation,of
R1340 T2165 T2163 conj loss,osteoarthritis
R1341 T2166 T2165 prep of,loss
R1342 T1975 T1974 cc and,formation
R1343 T2167 T2166 pobj mobility,of
R1344 T2168 T2155 punct .,fibrillates
R1345 T2170 T2171 det These,experiments
R1346 T2171 T2172 nsubj experiments,suggest
R1347 T1976 T1974 conj maintenance,formation
R1348 T2173 T2174 mark that,required
R1349 T2174 T2172 advcl required,suggest
R1350 T1977 T1956 punct .,be
R1351 T2175 T2176 compound BMP,signaling
R1352 T2176 T2174 nsubjpass signaling,required
R1353 T2177 T2174 auxpass is,required
R1354 T1979 T1980 advmod Here,take
R1355 T2178 T2174 prep for,required
R1356 T2179 T2180 amod normal,maintenance
R1357 T2180 T2178 pobj maintenance,for
R1358 T2181 T2180 prep of,maintenance
R1359 T1981 T1980 nsubj we,take
R1360 T2182 T2183 amod postnatal,cartilage
R1361 T2183 T2181 pobj cartilage,of
R1362 T2184 T2183 amod articular,cartilage
R1363 T1982 T1980 dobj advantage,take
R1364 T2185 T2174 punct ", ",required
R1365 T2186 T2174 cc and,required
R1366 T2187 T2188 mark that,play
R1367 T1983 T1980 prep of,take
R1368 T2188 T2174 conj play,required
R1369 T2189 T2188 nsubj modulation,play
R1370 T1984 T1985 det the,pattern
R1371 T2190 T2189 prep of,modulation
R1372 T2191 T2192 det the,pathway
R1373 T2192 T2190 pobj pathway,of
R1374 T1985 T1983 pobj pattern,of
R1375 T2193 T2194 compound BMP,signaling
R1376 T2194 T2192 compound signaling,pathway
R1377 T2195 T2188 aux may,play
R1378 T1986 T1987 npadvmod tissue,specific
R1379 T2196 T2197 det an,role
R1380 T2197 T2188 dobj role,play
R1381 T2198 T2197 amod important,role
R1382 T2199 T2188 prep in,play
R1383 T1987 T1985 amod specific,pattern
R1384 T2200 T2201 compound joint,disease
R1385 T2201 T2199 pobj disease,in
R1386 T1988 T1987 punct -,specific
R1387 T2202 T2172 punct .,suggest
R1388 T1989 T1985 compound expression,pattern
R1389 T1990 T1985 prep of,pattern
R1390 T1991 T1992 det the,gene
R1391 T1992 T1990 pobj gene,of
R1392 T1993 T1992 compound Gdf5,gene
R1393 T1994 T1995 aux to,engineer
R1394 T1995 T1980 advcl engineer,take
R1395 T1996 T1997 det a,system
R1396 T1997 T1995 dobj system,engineer
R1397 T1998 T1999 compound Cre,loxP
R1398 T1999 T1997 compound loxP,system
R1399 T2000 T1999 punct /,loxP
R1400 T2001 T2002 punct (,Nagy
R1401 T2002 T1997 meta Nagy,system
R1402 T2003 T2002 nummod 2000,Nagy
R1403 T2004 T2002 punct ),Nagy
R1404 T2005 T1997 punct ", ",system
R1405 T2006 T2007 compound Gdf5,Cre
R1406 T2007 T1997 appos Cre,system
R1407 T2008 T2007 punct -,Cre
R1408 T2009 T1997 punct ", ",system
R1409 T2010 T2011 dep that,used
R1410 T2011 T1997 relcl used,system
R1411 T2012 T2011 aux can,used
R1412 T2013 T2011 auxpass be,used

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T1028 2-9 SO_EXT:0000704 denotes genetic
T1029 48-53 SO_EXT:0000704 denotes genes
T1030 70-75 UBERON:0004905 denotes joint
T1031 76-83 UBERON:0000479 denotes tissues
T1032 136-141 UBERON:0004905 denotes joint
T1033 199-205 UBERON:0000479 denotes tissue
T1034 215-225 GO:0010467 denotes expression
T1035 241-245 PR_EXT:000000281 denotes Gdf5
T1036 246-250 SO_EXT:0000704 denotes gene
T1037 269-273 SO_EXT:0000346 denotes loxP
T1038 294-298 PR_EXT:000000281 denotes Gdf5
T1039 346-353 GO:0010467 denotes express
T1040 354-359 SO_EXT:0000704 denotes genes
T1041 363-369 UBERON:0004905 denotes joints
T1042 391-395 NCBITaxon:10088 denotes mice
T1043 432-441 SO_EXT:sequence_alteration_process denotes modifying
T1044 442-447 SO_EXT:0000704 denotes genes
T1045 487-501 UBERON:0002217 denotes synovial joint
T1046 517-526 UBERON:0000211 denotes ligaments
T1047 534-547 UBERON:0001484 denotes joint capsule
T1048 553-570 UBERON_EXT:synovial_membrane denotes synovial membrane
T1049 580-599 UBERON:0010996 denotes articular cartilage
T1050 601-605 PR_EXT:000000281 denotes Gdf5
T1051 610-623 GO_SO_EXT:sequence_rearrangement_process denotes recombination
T1052 637-652 UBERON:0019248 denotes early embryonic
T1053 653-662 GO_EXT:fatality_or_lethality denotes lethality
T1054 666-670 SO_EXT:sequence_nullness denotes null
T1055 671-680 SO_EXT:sequence_alteration_entity_or_process denotes mutations
T1056 684-690 PR_EXT:000000035 denotes Bmpr1a
T1057 712-720 GO_EXT:0004872 denotes receptor
T1058 743-748 UBERON:0004905 denotes joint
T1059 799-820 GO:0012501 denotes programmed cell death
T1060 810-814 CL_GO_EXT:cell denotes cell
T1061 824-846 UBERON:0006015 denotes webbing between digits
T1062 863-869 PR_EXT:000000035 denotes Bmpr1a
T1063 895-900 GO:0007567 denotes natal
T1064 916-935 UBERON:0010996 denotes articular cartilage
T1065 959-967 UBERON:0004288 denotes skeleton
T1066 972-976 PR_EXT:000000281 denotes Gdf5
T1067 981-987 PR_EXT:000000035 denotes Bmpr1a
T1068 987-992 SO:0000359 denotes floxP
T1069 993-997 NCBITaxon:10088 denotes mice
T1070 999-1018 UBERON:0010996 denotes articular cartilage
T1071 1068-1078 GO:0010467 denotes expression
T1072 1094-1103 UBERON_EXT:cartilage_element_or_tissue denotes cartilage
T1073 1104-1111 CHEBI_SO_EXT:molecular_indicator_or_label_or_marker_or_tag denotes markers
T1074 1118-1123 GO:0007567 denotes birth
T1075 1256-1259 PR_EXT:000000034 denotes BMP
T1076 1256-1269 GO:0030509 denotes BMP signaling
T1077 1312-1317 GO:0007567 denotes natal
T1078 1318-1337 UBERON:0010996 denotes articular cartilage
T1079 1348-1361 _FRAGMENT denotes modulation of
T1080 1366-1387 GO:0030510 denotes BMP signaling pathway
T1081 1366-1369 PR_EXT:000000034 denotes BMP
T1082 1418-1423 UBERON:0004905 denotes joint
R359 T1080 T1079 _lexicallyChainedTo BMP signaling pathway,modulation of

craft-ca-core-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T827 2-9 SO:0000704 denotes genetic
T828 48-53 SO:0000704 denotes genes
T829 70-75 UBERON:0004905 denotes joint
T830 76-83 UBERON:0000479 denotes tissues
T831 136-141 UBERON:0004905 denotes joint
T832 199-205 UBERON:0000479 denotes tissue
T833 215-225 GO:0010467 denotes expression
T834 241-245 PR:000000281 denotes Gdf5
T835 246-250 SO:0000704 denotes gene
T836 269-273 SO:0000346 denotes loxP
T837 294-298 PR:000000281 denotes Gdf5
T838 346-353 GO:0010467 denotes express
T839 354-359 SO:0000704 denotes genes
T840 363-369 UBERON:0004905 denotes joints
T841 391-395 NCBITaxon:10088 denotes mice
T842 442-447 SO:0000704 denotes genes
T843 487-501 UBERON:0002217 denotes synovial joint
T844 517-526 UBERON:0000211 denotes ligaments
T845 534-547 UBERON:0001484 denotes joint capsule
T846 580-599 UBERON:0010996 denotes articular cartilage
T847 601-605 PR:000000281 denotes Gdf5
T848 637-652 UBERON:0019248 denotes early embryonic
T849 684-690 PR:000000035 denotes Bmpr1a
T850 743-748 UBERON:0004905 denotes joint
T851 799-820 GO:0012501 denotes programmed cell death
T852 824-846 UBERON:0006015 denotes webbing between digits
T853 863-869 PR:000000035 denotes Bmpr1a
T854 895-900 GO:0007567 denotes natal
T855 916-935 UBERON:0010996 denotes articular cartilage
T856 959-967 UBERON:0004288 denotes skeleton
T857 972-976 PR:000000281 denotes Gdf5
T858 981-987 PR:000000035 denotes Bmpr1a
T859 987-992 SO:0000359 denotes floxP
T860 993-997 NCBITaxon:10088 denotes mice
T861 999-1018 UBERON:0010996 denotes articular cartilage
T862 1068-1078 GO:0010467 denotes expression
T863 1118-1123 GO:0007567 denotes birth
T864 1256-1259 PR:000000034 denotes BMP
T865 1256-1269 GO:0030509 denotes BMP signaling
T866 1312-1317 GO:0007567 denotes natal
T867 1318-1337 UBERON:0010996 denotes articular cartilage
T868 1348-1361 _FRAGMENT denotes modulation of
T869 1366-1387 GO:0030510 denotes BMP signaling pathway
T870 1366-1369 PR:000000034 denotes BMP
T871 1418-1423 UBERON:0004905 denotes joint
R355 T869 T868 _lexicallyChainedTo BMP signaling pathway,modulation of

2_test

Id Subject Object Predicate Lexical cue
15492776-10686599-84887300 287-291 10686599 denotes 2000
T37516 287-291 10686599 denotes 2000