PMC:521203 / 11143-11939 JSONTXT

{"target":"http://pubannotation.org/docs/sourcedb/PMC/sourceid/521203","sourcedb":"PMC","sourceid":"521203","source_url":"https://www.ncbi.nlm.nih.gov/pmc/521203","text":"The ability of donor cells to be reprogrammed was assessed by the development of cloned embryos in vitro and by the birth of cloned calves following embryo transfer. As shown in Tables 2 and 3, although no differences were detected in the cleavage rates of embryos from three different cell types, cumulus cells produced the highest rate of blastocyst development in this study and resulted in 6 full-term cloned calves. Furthermore, four out of the six calves derived from cumulus cells survived and were still healthy at nearly 4 years of age (Table 3). In contrast, the poorest in vitro development, and no full-term survival, was obtained with mammary epithelial cells. Skin fibroblast cells resulted in an intermediate rate of in vitro development and gave rise to 4 full-term cloned calves.","tracks":[]}