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PMC:516044 / 30321-32272 JSONTXT

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Id Subject Object Predicate Lexical cue
T7745 1950-1951 . denotes .
T7744 1942-1950 NN denotes syndrome
T7743 1934-1941 NNP denotes Pendred
T7742 1929-1933 IN denotes from
T7741 1919-1928 VBG denotes suffering
T7740 1910-1918 NNS denotes patients
T7739 1906-1909 CC denotes and
T7738 1899-1900 SYM denotes -
T7737 1898-1899 HYPH denotes /
T7736 1897-1898 SYM denotes -
T7735 1901-1905 NNS denotes mice
T7734 1890-1897 NN denotes Slc26a4
T7733 1887-1889 IN denotes in
T7732 1878-1886 NN denotes deafness
T7731 1875-1877 IN denotes of
T7730 1862-1868 JJ denotes direct
T7729 1869-1874 NN denotes cause
T7728 1858-1861 DT denotes the
T7727 1849-1857 RB denotes probably
T7726 1844-1846 , denotes ,
T7725 1822-1834 JJ denotes endocochlear
T7724 1835-1844 NN denotes potential
T7723 1818-1821 DT denotes the
T7722 1815-1817 IN denotes of
T7721 1804-1814 NN denotes generation
T7720 1800-1803 DT denotes the
T7719 1796-1799 IN denotes for
T7718 1786-1795 JJ denotes essential
T7717 1783-1785 VBZ denotes is
T7716 1777-1782 WDT denotes which
T7715 1775-1777 , denotes ,
T7714 1757-1769 JJ denotes intermediate
T7713 1770-1775 NNS denotes cells
T7712 1750-1756 JJ denotes strial
T7711 1747-1749 IN denotes in
T7710 1737-1738 SYM denotes +
T7709 1736-1737 NN denotes K
T7708 1729-1735 NN denotes KCNJ10
T7707 1739-1746 NN denotes channel
T7706 1725-1728 DT denotes the
T7705 1722-1724 IN denotes of
T7704 1846-1848 VBZ denotes is
T7703 1710-1721 NN denotes Suppression
T7702 1709-1951 sentence denotes Suppression of the KCNJ10 K+ channel in strial intermediate cells, which is essential for the generation of the endocochlear potential, is probably the direct cause of deafness in Slc26a4-/- mice and patients suffering from Pendred syndrome.
T7701 1708-1709 . denotes .
T7700 1707-1708 -RRB- denotes ]
T7699 1705-1707 CD denotes 39
T7698 1704-1705 -LRB- denotes [
T7697 1699-1703 NN denotes cell
T7696 1695-1698 DT denotes the
T7695 1692-1694 IN denotes of
T7694 1676-1685 JJ denotes metabolic
T7693 1686-1691 NN denotes state
T7692 1672-1675 DT denotes the
T7691 1665-1671 VBP denotes encode
T7690 1659-1664 WDT denotes which
T7689 1657-1659 , denotes ,
T7688 1649-1657 NNS denotes radicals
T7687 1644-1648 JJ denotes free
T7686 1640-1643 CC denotes and
T7685 1627-1636 JJ denotes cytosolic
T7684 1637-1639 NN denotes pH
T7683 1623-1626 DT denotes the
T7682 1620-1622 IN denotes by
T7681 1606-1608 VB denotes be
T7680 1609-1619 VBN denotes controlled
T7679 1603-1605 TO denotes to
T7678 1592-1596 VBN denotes been
T7677 1588-1591 VBZ denotes has
T7676 1577-1578 SYM denotes +
T7675 1576-1577 NN denotes K
T7674 1579-1587 NNS denotes channels
T7673 1570-1575 JJ denotes other
T7672 1567-1569 IN denotes of
T7671 1556-1566 NN denotes expression
T7670 1552-1555 CC denotes and
T7669 1597-1602 VBN denotes shown
T7668 1543-1551 NN denotes Function
T7667 1542-1709 sentence denotes Function and expression of other K+ channels has been shown to be controlled by the cytosolic pH and free radicals, which encode the metabolic state of the cell [39].
T7666 1541-1542 . denotes .
T7665 1523-1535 JJ denotes intermediate
T7664 1536-1541 NNS denotes cells
T7663 1516-1522 JJ denotes strial
T7662 1513-1515 IN denotes in
T7661 1494-1501 NN denotes protein
T7660 1502-1512 NN denotes expression
T7659 1487-1493 NN denotes KCNJ10
T7658 1484-1486 IN denotes of
T7657 1479-1483 NN denotes loss
T7656 1475-1478 DT denotes the
T7655 1472-1474 IN denotes to
T7654 1463-1466 MD denotes may
T7653 1456-1462 NN denotes stress
T7652 1448-1455 NN denotes radical
T7651 1443-1447 JJ denotes free
T7650 1438-1442 IN denotes with
T7649 1426-1437 NN denotes conjunction
T7648 1423-1425 IN denotes in
T7647 1410-1419 JJ denotes cytosolic
T7646 1420-1422 NN denotes pH
T7645 1406-1409 DT denotes the
T7644 1403-1405 IN denotes in
T7643 1467-1471 VB denotes lead
T7642 1391-1402 NNS denotes Alterations
T7641 1390-1542 sentence denotes Alterations in the cytosolic pH in conjunction with free radical stress may lead to the loss of KCNJ10 protein expression in strial intermediate cells.
T7640 1389-1390 . denotes .
T7639 1388-1389 -RRB- denotes ]
T7638 1386-1388 CD denotes 37
T7637 1385-1386 -LRB- denotes [
T7636 1378-1384 NN denotes trauma
T7635 1369-1377 JJ denotes acoustic
T7634 1366-1368 IN denotes as
T7633 1361-1365 JJ denotes such
T7632 1359-1361 , denotes ,
T7631 1353-1359 NN denotes stress
T7630 1345-1352 NN denotes radical
T7629 1340-1344 JJ denotes free
T7628 1335-1339 IN denotes with
T7627 1320-1323 VBP denotes are
T7626 1324-1334 VBN denotes associated
T7625 1315-1319 WDT denotes that
T7624 1304-1314 NNS denotes conditions
T7623 1298-1303 JJ denotes other
T7622 1295-1297 IN denotes in
T7621 1281-1285 VBN denotes been
T7620 1276-1280 RB denotes also
T7619 1272-1275 VBZ denotes has
T7618 1286-1294 VBN denotes observed
T7617 1254-1271 NN denotes hyperpigmentation
T7616 1247-1253 JJ denotes Strial
T7615 1246-1390 sentence denotes Strial hyperpigmentation has also been observed in other conditions that are associated with free radical stress, such as acoustic trauma [37].
T7614 1245-1246 . denotes .
T7613 1238-1245 NN denotes pendrin
T7612 1230-1237 VBG denotes lacking
T7611 1225-1229 NNS denotes mice
T7610 1222-1224 IN denotes in
T7609 1195-1203 VBN denotes observed
T7608 1204-1221 NN denotes hyperpigmentation
T7607 1191-1194 DT denotes the
T7606 1186-1190 IN denotes from
T7605 1165-1172 NN denotes radical
T7604 1160-1164 JJ denotes free
T7603 1173-1179 NN denotes stress
T7602 1151-1159 VBN denotes enhanced
T7601 1148-1150 IN denotes of
T7600 1137-1147 NN denotes hypothesis
T7599 1133-1136 DT denotes the
T7598 1129-1132 IN denotes for
T7597 1180-1185 VBZ denotes comes
T7596 1121-1128 NN denotes Support
T7595 1120-1246 sentence denotes Support for the hypothesis of enhanced free radical stress comes from the observed hyperpigmentation in mice lacking pendrin.
T7594 1119-1120 . denotes .
T7593 1118-1119 -RRB- denotes ]
T7592 1116-1118 CD denotes 38
T7591 1115-1116 -LRB- denotes [
T7590 1092-1102 JJ denotes protective
T7589 1103-1114 NN denotes glutathione
T7588 1088-1091 DT denotes the
T7587 1085-1087 IN denotes of
T7586 1074-1084 NN denotes production
T7585 1068-1073 VB denotes limit
T7584 1060-1067 RB denotes thereby
T7583 1056-1059 CC denotes and
T7582 1047-1055 NN denotes cysteine
T7581 1044-1046 IN denotes of
T7580 1037-1043 NN denotes uptake
T7579 1033-1036 DT denotes the
T7578 1021-1024 MD denotes may
T7577 1018-1020 PRP denotes it
T7576 1025-1032 VB denotes inhibit
T7575 1012-1017 IN denotes since
T7574 1010-1012 , denotes ,
T7573 1004-1010 NN denotes stress
T7572 996-1003 NN denotes radical
T7571 991-995 JJ denotes free
T7570 979-982 MD denotes may
T7569 983-990 VB denotes enhance
T7568 950-963 JJ denotes extracellular
T7567 964-978 NN denotes alkalinization
T7566 945-949 DT denotes This
T7565 944-1120 sentence denotes This extracellular alkalinization may enhance free radical stress, since it may inhibit the uptake of cysteine and thereby limit production of the protective glutathione [38].
T7564 943-944 . denotes .
T7563 925-936 JJ denotes intrastrial
T7562 937-943 NNS denotes spaces
T7561 921-924 DT denotes the
T7560 918-920 IN denotes of
T7559 903-917 NN denotes alkalinization
T7558 900-902 DT denotes an
T7557 896-899 CC denotes and
T7556 894-895 SYM denotes -
T7555 889-893 NN denotes HCO3
T7554 886-888 IN denotes of
T7553 873-885 NN denotes accumulation
T7552 870-872 DT denotes an
T7551 867-869 IN denotes in
T7550 857-859 , denotes ,
T7549 848-857 NN denotes endolymph
T7548 843-847 IN denotes into
T7547 841-842 SYM denotes -
T7546 836-840 NN denotes HCO3
T7545 824-827 MD denotes may
T7544 828-835 VB denotes secrete
T7543 818-823 WDT denotes which
T7542 816-818 , denotes ,
T7541 809-816 NN denotes pendrin
T7540 806-808 IN denotes of
T7539 801-805 NN denotes loss
T7538 859-866 VBZ denotes results
T7537 796-800 IN denotes that
T7536 784-795 JJ denotes conceivable
T7535 781-783 VBZ denotes is
T7534 778-780 PRP denotes It
T7533 777-944 sentence denotes It is conceivable that loss of pendrin, which may secrete HCO3 - into endolymph, results in an accumulation of HCO3 - and an alkalinization of the intrastrial spaces.
T7532 776-777 . denotes .
T7531 775-776 -RRB- denotes ]
T7530 773-775 CD denotes 37
T7529 772-773 SYM denotes -
T7528 770-772 CD denotes 34
T7527 769-770 -LRB- denotes [
T7526 761-768 NN denotes pigment
T7525 753-760 NN denotes melanin
T7524 749-752 CC denotes and
T7523 737-748 NN denotes glutathione
T7522 722-727 NNS denotes cells
T7521 709-721 JJ denotes intermediate
T7520 707-709 , denotes ,
T7519 693-700 NN denotes radical
T7518 701-707 NN denotes damage
T7517 688-692 JJ denotes free
T7516 683-687 IN denotes from
T7515 672-682 PRP denotes themselves
T7514 728-736 VBP denotes generate
T7513 664-671 VB denotes protect
T7512 661-663 TO denotes To
T7511 660-777 sentence denotes To protect themselves from free radical damage, intermediate cells generate glutathione and melanin pigment [34-37].
T7510 659-660 . denotes .
T7509 651-659 NNS denotes radicals
T7508 646-650 JJ denotes free
T7507 637-645 VB denotes detoxify
T7506 634-636 TO denotes to
T7505 625-633 NN denotes catalase
T7504 621-624 CC denotes and
T7503 619-620 -RRB- denotes ]
T7502 616-617 , denotes ,
T7501 614-616 CD denotes 18
T7500 617-619 CD denotes 19
T7499 613-614 -LRB- denotes [
T7498 611-612 SYM denotes -
T7497 606-610 NN denotes HCO3
T7496 603-605 IN denotes to
T7495 599-602 NN denotes CO2
T7494 591-598 VB denotes convert
T7493 588-590 TO denotes to
T7492 578-587 NN denotes anhydrase
T7491 569-577 JJ denotes carbonic
T7490 562-568 VBP denotes employ
T7489 556-561 NNS denotes cells
T7488 543-555 JJ denotes Intermediate
T7487 542-660 sentence denotes Intermediate cells employ carbonic anhydrase to convert CO2 to HCO3 - [18,19] and catalase to detoxify free radicals.
T7486 541-542 . denotes .
T7485 527-535 JJ denotes marginal
T7484 520-526 JJ denotes strial
T7483 506-512 RB denotes highly
T7482 513-519 JJ denotes active
T7481 492-505 RB denotes metabolically
T7480 536-541 NNS denotes cells
T7479 488-491 DT denotes the
T7478 485-487 IN denotes in
T7477 472-484 NNS denotes mitochondria
T7476 469-471 IN denotes of
T7475 455-460 JJ denotes large
T7474 461-468 NNS denotes numbers
T7473 451-454 DT denotes the
T7472 448-450 IN denotes by
T7471 434-437 VBP denotes are
T7470 425-433 NNS denotes radicals
T7469 420-424 JJ denotes free
T7468 416-419 CC denotes and
T7467 438-447 VBN denotes generated
T7466 412-415 NN denotes CO2
T7465 411-542 sentence denotes CO2 and free radicals are generated by the large numbers of mitochondria in the metabolically highly active strial marginal cells.
T7464 410-411 . denotes .
T7463 409-410 -RRB- denotes )
T7462 408-409 CD denotes 9
T7461 403-407 NN denotes Fig.
T7460 402-403 -LRB- denotes (
T7459 393-401 NNS denotes radicals
T7458 388-392 JJ denotes free
T7457 376-387 VBG denotes detoxifying
T7456 373-375 IN denotes by
T7455 369-372 CC denotes and
T7454 367-368 SYM denotes -
T7453 362-366 NN denotes HCO3
T7452 359-361 IN denotes to
T7451 355-358 NN denotes CO2
T7450 344-354 VBG denotes converting
T7449 341-343 IN denotes by
T7448 330-340 NN denotes vascularis
T7447 324-329 NN denotes stria
T7446 316-323 VBP denotes protect
T7445 310-315 NNS denotes cells
T7444 297-309 JJ denotes Intermediate
T7443 296-411 sentence denotes Intermediate cells protect stria vascularis by converting CO2 to HCO3 - and by detoxifying free radicals (Fig. 9).
T7442 295-296 . denotes .
T7441 288-295 NN denotes protein
T7440 281-287 NN denotes KCNJ10
T7439 269-272 RB denotes not
T7438 266-268 VBP denotes do
T7437 261-265 PRP denotes they
T7436 273-280 VB denotes express
T7435 253-260 IN denotes because
T7434 230-242 JJ denotes endocochlear
T7433 243-252 NN denotes potential
T7432 226-229 DT denotes the
T7431 214-215 SYM denotes -
T7430 213-214 HYPH denotes /
T7429 212-213 SYM denotes -
T7428 216-220 NNS denotes mice
T7427 205-212 NN denotes Slc26a4
T7426 221-225 VBP denotes lack
T7425 200-204 IN denotes that
T7424 194-199 VBD denotes found
T7423 191-193 PRP denotes We
T7422 190-296 sentence denotes We found that Slc26a4-/- mice lack the endocochlear potential because they do not express KCNJ10 protein.
T7421 189-190 . denotes .
T7420 172-177 NN denotes fluid
T7419 178-189 NN denotes compartment
T7418 167-171 DT denotes this
T7417 164-166 IN denotes of
T7416 152-163 NN denotes enlargement
T7415 149-151 DT denotes an
T7414 146-148 IN denotes of
T7413 140-145 NN denotes spite
T7412 137-139 IN denotes in
T7411 120-121 SYM denotes +
T7410 119-120 NN denotes K
T7409 105-118 JJ denotes endolymphatic
T7408 122-136 NNS denotes concentrations
T7407 98-104 JJ denotes normal
T7406 89-97 VBD denotes detected
T7405 85-88 CC denotes and
T7404 75-84 NN denotes labyrinth
T7403 64-74 JJ denotes vestibular
T7402 60-63 CC denotes and
T7401 52-59 NN denotes cochlea
T7400 48-51 DT denotes the
T7399 45-47 IN denotes in
T7398 34-44 NN denotes expression
T7397 26-33 NN denotes pendrin
T7396 23-25 IN denotes of
T7395 13-22 NNS denotes locations
T7394 3-12 VBD denotes described
T7393 0-2 PRP denotes We
R4510 T7393 T7394 nsubj We,described
R4511 T7395 T7394 dobj locations,described
R4512 T7396 T7395 prep of,locations
R4513 T7397 T7398 compound pendrin,expression
R4514 T7398 T7396 pobj expression,of
R4515 T7399 T7395 prep in,locations
R4516 T7400 T7401 det the,cochlea
R4517 T7401 T7399 pobj cochlea,in
R4518 T7402 T7401 cc and,cochlea
R4519 T7403 T7404 amod vestibular,labyrinth
R4520 T7404 T7401 conj labyrinth,cochlea
R4521 T7405 T7394 cc and,described
R4522 T7406 T7394 conj detected,described
R4523 T7407 T7408 amod normal,concentrations
R4524 T7408 T7406 dobj concentrations,detected
R4525 T7409 T7408 amod endolymphatic,concentrations
R4526 T7410 T7408 nmod K,concentrations
R4527 T7411 T7410 punct +,K
R4528 T7412 T7406 prep in,detected
R4529 T7413 T7412 pobj spite,in
R4530 T7414 T7413 prep of,spite
R4531 T7415 T7416 det an,enlargement
R4532 T7416 T7414 pobj enlargement,of
R4533 T7417 T7416 prep of,enlargement
R4534 T7418 T7419 det this,compartment
R4535 T7419 T7417 pobj compartment,of
R4536 T7420 T7419 compound fluid,compartment
R4537 T7421 T7394 punct .,described
R4538 T7423 T7424 nsubj We,found
R4539 T7425 T7426 mark that,lack
R4540 T7426 T7424 ccomp lack,found
R4541 T7427 T7428 nmod Slc26a4,mice
R4542 T7428 T7426 nsubj mice,lack
R4543 T7429 T7427 punct -,Slc26a4
R4544 T7430 T7427 punct /,Slc26a4
R4545 T7431 T7427 punct -,Slc26a4
R4546 T7432 T7433 det the,potential
R4547 T7433 T7426 dobj potential,lack
R4548 T7434 T7433 amod endocochlear,potential
R4549 T7435 T7436 mark because,express
R4550 T7436 T7426 advcl express,lack
R4551 T7437 T7436 nsubj they,express
R4552 T7438 T7436 aux do,express
R4553 T7439 T7436 neg not,express
R4554 T7440 T7441 compound KCNJ10,protein
R4555 T7441 T7436 dobj protein,express
R4556 T7442 T7424 punct .,found
R4557 T7444 T7445 amod Intermediate,cells
R4558 T7445 T7446 nsubj cells,protect
R4559 T7447 T7448 compound stria,vascularis
R4560 T7448 T7446 dobj vascularis,protect
R4561 T7449 T7446 prep by,protect
R4562 T7450 T7449 pcomp converting,by
R4563 T7451 T7450 dobj CO2,converting
R4564 T7452 T7450 prep to,converting
R4565 T7453 T7452 pobj HCO3,to
R4566 T7454 T7453 punct -,HCO3
R4567 T7455 T7449 cc and,by
R4568 T7456 T7449 conj by,by
R4569 T7457 T7456 pcomp detoxifying,by
R4570 T7458 T7459 amod free,radicals
R4571 T7459 T7457 dobj radicals,detoxifying
R4572 T7460 T7461 punct (,Fig.
R4573 T7461 T7446 parataxis Fig.,protect
R4574 T7462 T7461 nummod 9,Fig.
R4575 T7463 T7461 punct ),Fig.
R4576 T7464 T7446 punct .,protect
R4577 T7466 T7467 nsubjpass CO2,generated
R4578 T7468 T7466 cc and,CO2
R4579 T7469 T7470 amod free,radicals
R4580 T7470 T7466 conj radicals,CO2
R4581 T7471 T7467 auxpass are,generated
R4582 T7472 T7467 agent by,generated
R4583 T7473 T7474 det the,numbers
R4584 T7474 T7472 pobj numbers,by
R4585 T7475 T7474 amod large,numbers
R4586 T7476 T7474 prep of,numbers
R4587 T7477 T7476 pobj mitochondria,of
R4588 T7478 T7474 prep in,numbers
R4589 T7479 T7480 det the,cells
R4590 T7480 T7478 pobj cells,in
R4591 T7481 T7482 advmod metabolically,active
R4592 T7482 T7480 amod active,cells
R4593 T7483 T7482 advmod highly,active
R4594 T7484 T7485 amod strial,marginal
R4595 T7485 T7480 amod marginal,cells
R4596 T7486 T7467 punct .,generated
R4597 T7488 T7489 amod Intermediate,cells
R4598 T7489 T7490 nsubj cells,employ
R4599 T7491 T7492 amod carbonic,anhydrase
R4600 T7492 T7490 dobj anhydrase,employ
R4601 T7493 T7494 aux to,convert
R4602 T7494 T7490 advcl convert,employ
R4603 T7495 T7494 dobj CO2,convert
R4604 T7496 T7494 prep to,convert
R4605 T7497 T7496 pobj HCO3,to
R4606 T7498 T7497 punct -,HCO3
R4607 T7499 T7500 punct [,19
R4608 T7500 T7494 parataxis 19,convert
R4609 T7501 T7500 nummod 18,19
R4610 T7502 T7500 punct ",",19
R4611 T7503 T7500 punct ],19
R4612 T7504 T7490 cc and,employ
R4613 T7505 T7490 conj catalase,employ
R4614 T7506 T7507 aux to,detoxify
R4615 T7507 T7505 advcl detoxify,catalase
R4616 T7508 T7509 amod free,radicals
R4617 T7509 T7507 dobj radicals,detoxify
R4618 T7510 T7490 punct .,employ
R4619 T7512 T7513 aux To,protect
R4620 T7513 T7514 advcl protect,generate
R4621 T7515 T7513 dobj themselves,protect
R4622 T7516 T7513 prep from,protect
R4623 T7517 T7518 amod free,damage
R4624 T7518 T7516 pobj damage,from
R4625 T7519 T7518 compound radical,damage
R4626 T7520 T7514 punct ", ",generate
R4627 T7521 T7522 amod intermediate,cells
R4628 T7522 T7514 nsubj cells,generate
R4629 T7523 T7514 dobj glutathione,generate
R4630 T7524 T7523 cc and,glutathione
R4631 T7525 T7526 compound melanin,pigment
R4632 T7526 T7523 conj pigment,glutathione
R4633 T7527 T7528 punct [,34
R4634 T7528 T7514 parataxis 34,generate
R4635 T7529 T7530 punct -,37
R4636 T7530 T7528 prep 37,34
R4637 T7531 T7528 punct ],34
R4638 T7532 T7514 punct .,generate
R4639 T7534 T7535 nsubj It,is
R4640 T7536 T7535 acomp conceivable,is
R4641 T7537 T7538 mark that,results
R4642 T7538 T7535 ccomp results,is
R4643 T7539 T7538 nsubj loss,results
R4644 T7540 T7539 prep of,loss
R4645 T7541 T7540 pobj pendrin,of
R4646 T7542 T7541 punct ", ",pendrin
R4647 T7543 T7544 dep which,secrete
R4648 T7544 T7541 relcl secrete,pendrin
R4649 T7545 T7544 aux may,secrete
R4650 T7546 T7544 dobj HCO3,secrete
R4651 T7547 T7546 punct -,HCO3
R4652 T7548 T7544 prep into,secrete
R4653 T7549 T7548 pobj endolymph,into
R4654 T7550 T7538 punct ", ",results
R4655 T7551 T7538 prep in,results
R4656 T7552 T7553 det an,accumulation
R4657 T7553 T7551 pobj accumulation,in
R4658 T7554 T7553 prep of,accumulation
R4659 T7555 T7554 pobj HCO3,of
R4660 T7556 T7555 punct -,HCO3
R4661 T7557 T7553 cc and,accumulation
R4662 T7558 T7559 det an,alkalinization
R4663 T7559 T7553 conj alkalinization,accumulation
R4664 T7560 T7559 prep of,alkalinization
R4665 T7561 T7562 det the,spaces
R4666 T7562 T7560 pobj spaces,of
R4667 T7563 T7562 amod intrastrial,spaces
R4668 T7564 T7535 punct .,is
R4669 T7566 T7567 det This,alkalinization
R4670 T7567 T7569 nsubj alkalinization,enhance
R4671 T7568 T7567 amod extracellular,alkalinization
R4672 T7570 T7569 aux may,enhance
R4673 T7571 T7572 amod free,radical
R4674 T7572 T7573 compound radical,stress
R4675 T7573 T7569 dobj stress,enhance
R4676 T7574 T7569 punct ", ",enhance
R4677 T7575 T7576 mark since,inhibit
R4678 T7576 T7569 advcl inhibit,enhance
R4679 T7577 T7576 nsubj it,inhibit
R4680 T7578 T7576 aux may,inhibit
R4681 T7579 T7580 det the,uptake
R4682 T7580 T7576 dobj uptake,inhibit
R4683 T7581 T7580 prep of,uptake
R4684 T7582 T7581 pobj cysteine,of
R4685 T7583 T7576 cc and,inhibit
R4686 T7584 T7585 advmod thereby,limit
R4687 T7585 T7576 conj limit,inhibit
R4688 T7586 T7585 dobj production,limit
R4689 T7587 T7586 prep of,production
R4690 T7588 T7589 det the,glutathione
R4691 T7589 T7587 pobj glutathione,of
R4692 T7590 T7589 amod protective,glutathione
R4693 T7591 T7592 punct [,38
R4694 T7592 T7569 parataxis 38,enhance
R4695 T7593 T7592 punct ],38
R4696 T7594 T7569 punct .,enhance
R4697 T7596 T7597 nsubj Support,comes
R4698 T7598 T7596 prep for,Support
R4699 T7599 T7600 det the,hypothesis
R4700 T7600 T7598 pobj hypothesis,for
R4701 T7601 T7600 prep of,hypothesis
R4702 T7602 T7603 amod enhanced,stress
R4703 T7603 T7601 pobj stress,of
R4704 T7604 T7605 amod free,radical
R4705 T7605 T7603 compound radical,stress
R4706 T7606 T7597 prep from,comes
R4707 T7607 T7608 det the,hyperpigmentation
R4708 T7608 T7606 pobj hyperpigmentation,from
R4709 T7609 T7608 amod observed,hyperpigmentation
R4710 T7610 T7608 prep in,hyperpigmentation
R4711 T7611 T7610 pobj mice,in
R4712 T7612 T7611 acl lacking,mice
R4713 T7613 T7612 dobj pendrin,lacking
R4714 T7614 T7597 punct .,comes
R4715 T7616 T7617 amod Strial,hyperpigmentation
R4716 T7617 T7618 nsubjpass hyperpigmentation,observed
R4717 T7619 T7618 aux has,observed
R4718 T7620 T7618 advmod also,observed
R4719 T7621 T7618 auxpass been,observed
R4720 T7622 T7618 prep in,observed
R4721 T7623 T7624 amod other,conditions
R4722 T7624 T7622 pobj conditions,in
R4723 T7625 T7626 dep that,associated
R4724 T7626 T7624 relcl associated,conditions
R4725 T7627 T7626 auxpass are,associated
R4726 T7628 T7626 prep with,associated
R4727 T7629 T7630 amod free,radical
R4728 T7630 T7631 compound radical,stress
R4729 T7631 T7628 pobj stress,with
R4730 T7632 T7624 punct ", ",conditions
R4731 T7633 T7634 amod such,as
R4732 T7634 T7624 prep as,conditions
R4733 T7635 T7636 amod acoustic,trauma
R4734 T7636 T7634 pobj trauma,as
R4735 T7637 T7638 punct [,37
R4736 T7638 T7618 parataxis 37,observed
R4737 T7639 T7638 punct ],37
R4738 T7640 T7618 punct .,observed
R4739 T7642 T7643 nsubj Alterations,lead
R4740 T7644 T7642 prep in,Alterations
R4741 T7645 T7646 det the,pH
R4742 T7646 T7644 pobj pH,in
R4743 T7647 T7646 amod cytosolic,pH
R4744 T7648 T7642 prep in,Alterations
R4745 T7649 T7648 pobj conjunction,in
R4746 T7650 T7649 prep with,conjunction
R4747 T7651 T7652 amod free,radical
R4748 T7652 T7653 compound radical,stress
R4749 T7653 T7650 pobj stress,with
R4750 T7654 T7643 aux may,lead
R4751 T7655 T7643 prep to,lead
R4752 T7656 T7657 det the,loss
R4753 T7657 T7655 pobj loss,to
R4754 T7658 T7657 prep of,loss
R4755 T7659 T7660 compound KCNJ10,expression
R4756 T7660 T7658 pobj expression,of
R4757 T7661 T7660 compound protein,expression
R4758 T7662 T7643 prep in,lead
R4759 T7663 T7664 amod strial,cells
R4760 T7664 T7662 pobj cells,in
R4761 T7665 T7664 amod intermediate,cells
R4762 T7666 T7643 punct .,lead
R4763 T7668 T7669 nsubjpass Function,shown
R4764 T7670 T7668 cc and,Function
R4765 T7671 T7668 conj expression,Function
R4766 T7672 T7668 prep of,Function
R4767 T7673 T7674 amod other,channels
R4768 T7674 T7672 pobj channels,of
R4769 T7675 T7674 nmod K,channels
R4770 T7676 T7675 punct +,K
R4771 T7677 T7669 aux has,shown
R4772 T7678 T7669 auxpass been,shown
R4773 T7679 T7680 aux to,controlled
R4774 T7680 T7669 xcomp controlled,shown
R4775 T7681 T7680 auxpass be,controlled
R4776 T7682 T7680 agent by,controlled
R4777 T7683 T7684 det the,pH
R4778 T7684 T7682 pobj pH,by
R4779 T7685 T7684 amod cytosolic,pH
R4780 T7686 T7684 cc and,pH
R4781 T7687 T7688 amod free,radicals
R4782 T7688 T7684 conj radicals,pH
R4783 T7689 T7684 punct ", ",pH
R4784 T7690 T7691 dep which,encode
R4785 T7691 T7684 relcl encode,pH
R4786 T7692 T7693 det the,state
R4787 T7693 T7691 dobj state,encode
R4788 T7694 T7693 amod metabolic,state
R4789 T7695 T7693 prep of,state
R4790 T7696 T7697 det the,cell
R4791 T7697 T7695 pobj cell,of
R4792 T7698 T7699 punct [,39
R4793 T7699 T7669 parataxis 39,shown
R4794 T7700 T7699 punct ],39
R4795 T7701 T7669 punct .,shown
R4796 T7703 T7704 nsubj Suppression,is
R4797 T7705 T7703 prep of,Suppression
R4798 T7706 T7707 det the,channel
R4799 T7707 T7705 pobj channel,of
R4800 T7708 T7707 nmod KCNJ10,channel
R4801 T7709 T7707 nmod K,channel
R4802 T7710 T7709 punct +,K
R4803 T7711 T7703 prep in,Suppression
R4804 T7712 T7713 amod strial,cells
R4805 T7713 T7711 pobj cells,in
R4806 T7714 T7713 amod intermediate,cells
R4807 T7715 T7703 punct ", ",Suppression
R4808 T7716 T7717 dep which,is
R4809 T7717 T7703 relcl is,Suppression
R4810 T7718 T7717 acomp essential,is
R4811 T7719 T7718 prep for,essential
R4812 T7720 T7721 det the,generation
R4813 T7721 T7719 pobj generation,for
R4814 T7722 T7721 prep of,generation
R4815 T7723 T7724 det the,potential
R4816 T7724 T7722 pobj potential,of
R4817 T7725 T7724 amod endocochlear,potential
R4818 T7726 T7704 punct ", ",is
R4819 T7727 T7704 advmod probably,is
R4820 T7728 T7729 det the,cause
R4821 T7729 T7704 attr cause,is
R4822 T7730 T7729 amod direct,cause
R4823 T7731 T7729 prep of,cause
R4824 T7732 T7731 pobj deafness,of
R4825 T7733 T7729 prep in,cause
R4826 T7734 T7735 nmod Slc26a4,mice
R4827 T7735 T7733 pobj mice,in
R4828 T7736 T7734 punct -,Slc26a4
R4829 T7737 T7734 punct /,Slc26a4
R4830 T7738 T7734 punct -,Slc26a4
R4831 T7739 T7735 cc and,mice
R4832 T7740 T7735 conj patients,mice
R4833 T7741 T7740 acl suffering,patients
R4834 T7742 T7741 prep from,suffering
R4835 T7743 T7744 compound Pendred,syndrome
R4836 T7744 T7742 pobj syndrome,from
R4837 T7745 T7704 punct .,is

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T7392 1901-1905 NCBITaxon:10088 denotes mice
T7391 1899-1900 SO_EXT:sequence_nullness_or_absence denotes -
T7390 1897-1898 SO_EXT:sequence_nullness_or_absence denotes -
T7389 1890-1897 PR_EXT:000015039 denotes Slc26a4
T7388 1770-1775 CL_GO_EXT:cell denotes cells
T7387 1750-1775 CL:0002486 denotes strial intermediate cells
T7386 1750-1756 UBERON:0002282 denotes strial
T7385 1736-1746 GO_EXT:0005267 denotes K+ channel
T7384 1736-1738 CHEBI:29103 denotes K+
T7383 1729-1735 PR_EXT:000001979 denotes KCNJ10
T7382 1699-1703 CL_GO_EXT:cell denotes cell
T7381 1676-1685 GO:0008152 denotes metabolic
T7380 1644-1657 CHEBI:26519 denotes free radicals
T7379 1627-1636 GO:0005829 denotes cytosolic
T7378 1609-1619 GO:0065007 denotes controlled
T7377 1576-1587 GO_EXT:0005267 denotes K+ channels
T7376 1576-1578 CHEBI:29103 denotes K+
T7375 1556-1566 GO:0010467 denotes expression
T7374 1536-1541 CL_GO_EXT:cell denotes cells
T7373 1516-1541 CL:0002486 denotes strial intermediate cells
T7372 1516-1522 UBERON:0002282 denotes strial
T7371 1502-1512 GO:0010467 denotes expression
T7370 1494-1501 CHEBI_PR_EXT:protein denotes protein
T7369 1487-1493 PR_EXT:000001979 denotes KCNJ10
T7368 1443-1455 CHEBI:26519 denotes free radical
T7367 1410-1419 GO:0005829 denotes cytosolic
T7366 1340-1352 CHEBI:26519 denotes free radical
T7365 1259-1271 GO_PATO_EXT:biological_pigmentation_process_or_quality denotes pigmentation
T7364 1238-1245 PR_EXT:000015039 denotes pendrin
T7363 1225-1229 NCBITaxon:10088 denotes mice
T7362 1209-1221 GO_PATO_EXT:biological_pigmentation_process_or_quality denotes pigmentation
T7361 1160-1172 CHEBI:26519 denotes free radical
T7360 1103-1114 CHEBI:16856 denotes glutathione
T7359 1103-1114 GO:0006750 denotes glutathione
T7358 1074-1087 _FRAGMENT denotes production of
T7357 1047-1055 CHEBI_SO_EXT:cysteine denotes cysteine
T7356 991-1003 CHEBI:26519 denotes free radical
T7355 955-963 CL_GO_EXT:cell denotes cellular
T7354 950-963 GO:0005576 denotes extracellular
T7353 930-936 UBERON:0002282 denotes strial
T7352 889-895 CHEBI:17544 denotes HCO3 -
T7351 848-857 UBERON:0001852 denotes endolymph
T7350 836-842 CHEBI:17544 denotes HCO3 -
T7349 828-835 GO:0046903 denotes secrete
T7348 809-816 PR_EXT:000015039 denotes pendrin
T7347 761-768 CHEBI_EXT:26130 denotes pigment
T7346 753-760 CHEBI:25179 denotes melanin
T7345 737-748 CHEBI:16856 denotes glutathione
T7344 722-727 CL_GO_EXT:cell denotes cells
T7343 709-727 CL:0002486 denotes intermediate cells
T7342 688-700 CHEBI:26519 denotes free radical
T7341 646-659 CHEBI:26519 denotes free radicals
T7340 637-645 GO:0098754 denotes detoxify
T7339 625-633 GO_PR_EXT:catalase denotes catalase
T7338 606-612 CHEBI:17544 denotes HCO3 -
T7337 599-602 CHEBI:16526 denotes CO2
T7336 569-587 GO_EXT:0004089 denotes carbonic anhydrase
T7335 556-561 CL_GO_EXT:cell denotes cells
T7334 543-561 CL:0002486 denotes Intermediate cells
T7333 536-541 CL_GO_EXT:cell denotes cells
T7332 520-541 CL:0002492 denotes strial marginal cells
T7331 520-526 UBERON:0002282 denotes strial
T7330 492-505 GO:0008152 denotes metabolically
T7329 472-484 GO:0005739 denotes mitochondria
T7328 420-433 CHEBI:26519 denotes free radicals
T7327 412-415 CHEBI:16526 denotes CO2
T7326 388-401 CHEBI:26519 denotes free radicals
T7325 376-387 GO:0098754 denotes detoxifying
T7324 362-368 CHEBI:17544 denotes HCO3 -
T7323 355-358 CHEBI:16526 denotes CO2
T7322 324-340 UBERON:0002282 denotes stria vascularis
T7321 310-315 CL_GO_EXT:cell denotes cells
T7320 297-315 CL:0002486 denotes Intermediate cells
T7319 281-287 PR_EXT:000001979 denotes KCNJ10
T7318 273-280 GO:0010467 denotes express
T7317 216-220 NCBITaxon:10088 denotes mice
T7316 214-215 SO_EXT:sequence_nullness_or_absence denotes -
T7315 212-213 SO_EXT:sequence_nullness_or_absence denotes -
T7314 205-212 PR_EXT:000015039 denotes Slc26a4
T7313 119-121 CHEBI:29103 denotes K+
T7312 105-118 UBERON:0001852 denotes endolymphatic
T7311 64-84 UBERON:0001862 denotes vestibular labyrinth
T7310 52-59 UBERON:0001844 denotes cochlea
T7309 34-44 GO:0010467 denotes expression
T7308 26-33 PR_EXT:000015039 denotes pendrin
T7307 288-295 CHEBI_PR_EXT:protein denotes protein
R4509 T7359 T7358 _lexicallyChainedTo glutathione,production of

craft-ca-core-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T7306 1901-1905 NCBITaxon:10088 denotes mice
T7305 1890-1897 PR:000015039 denotes Slc26a4
T7304 1750-1775 CL:0002486 denotes strial intermediate cells
T7303 1750-1756 UBERON:0002282 denotes strial
T7302 1736-1738 CHEBI:29103 denotes K+
T7301 1729-1735 PR:000001979 denotes KCNJ10
T7300 1676-1685 GO:0008152 denotes metabolic
T7299 1644-1657 CHEBI:26519 denotes free radicals
T7298 1627-1636 GO:0005829 denotes cytosolic
T7297 1609-1619 GO:0065007 denotes controlled
T7296 1576-1578 CHEBI:29103 denotes K+
T7295 1556-1566 GO:0010467 denotes expression
T7294 1516-1541 CL:0002486 denotes strial intermediate cells
T7293 1516-1522 UBERON:0002282 denotes strial
T7292 1502-1512 GO:0010467 denotes expression
T7291 1487-1493 PR:000001979 denotes KCNJ10
T7290 1443-1455 CHEBI:26519 denotes free radical
T7289 1410-1419 GO:0005829 denotes cytosolic
T7288 1340-1352 CHEBI:26519 denotes free radical
T7287 1238-1245 PR:000015039 denotes pendrin
T7286 1225-1229 NCBITaxon:10088 denotes mice
T7285 1160-1172 CHEBI:26519 denotes free radical
T7284 1103-1114 CHEBI:16856 denotes glutathione
T7283 1103-1114 GO:0006750 denotes glutathione
T7282 1074-1087 _FRAGMENT denotes production of
T7281 991-1003 CHEBI:26519 denotes free radical
T7280 950-963 GO:0005576 denotes extracellular
T7279 930-936 UBERON:0002282 denotes strial
T7278 889-895 CHEBI:17544 denotes HCO3 -
T7277 848-857 UBERON:0001852 denotes endolymph
T7276 836-842 CHEBI:17544 denotes HCO3 -
T7275 828-835 GO:0046903 denotes secrete
T7274 809-816 PR:000015039 denotes pendrin
T7273 761-768 CHEBI:26130 denotes pigment
T7272 753-760 CHEBI:25179 denotes melanin
T7271 737-748 CHEBI:16856 denotes glutathione
T7270 709-727 CL:0002486 denotes intermediate cells
T7269 688-700 CHEBI:26519 denotes free radical
T7268 646-659 CHEBI:26519 denotes free radicals
T7267 637-645 GO:0098754 denotes detoxify
T7266 606-612 CHEBI:17544 denotes HCO3 -
T7265 599-602 CHEBI:16526 denotes CO2
T7264 543-561 CL:0002486 denotes Intermediate cells
T7263 520-541 CL:0002492 denotes strial marginal cells
T7262 520-526 UBERON:0002282 denotes strial
T7261 492-505 GO:0008152 denotes metabolically
T7260 472-484 GO:0005739 denotes mitochondria
T7259 420-433 CHEBI:26519 denotes free radicals
T7258 412-415 CHEBI:16526 denotes CO2
T7257 388-401 CHEBI:26519 denotes free radicals
T7256 376-387 GO:0098754 denotes detoxifying
T7255 362-368 CHEBI:17544 denotes HCO3 -
T7254 355-358 CHEBI:16526 denotes CO2
T7253 324-340 UBERON:0002282 denotes stria vascularis
T7252 297-315 CL:0002486 denotes Intermediate cells
T7251 281-287 PR:000001979 denotes KCNJ10
T7250 273-280 GO:0010467 denotes express
T7249 216-220 NCBITaxon:10088 denotes mice
T7248 205-212 PR:000015039 denotes Slc26a4
T7247 119-121 CHEBI:29103 denotes K+
T7246 105-118 UBERON:0001852 denotes endolymphatic
T7245 64-84 UBERON:0001862 denotes vestibular labyrinth
T7244 52-59 UBERON:0001844 denotes cochlea
T7243 34-44 GO:0010467 denotes expression
T7242 26-33 PR:000015039 denotes pendrin
R4508 T7283 T7282 _lexicallyChainedTo glutathione,production of

2_test

Id Subject Object Predicate Lexical cue
15320950-8911971-12070989 614-616 8911971 denotes 18
15320950-6424489-12070990 617-619 6424489 denotes 19
15320950-87995-12070991 770-772 87995 denotes 34
15320950-11388439-12070991 770-772 11388439 denotes 34
15320950-9017265-12070991 770-772 9017265 denotes 34
15320950-1631019-12070991 770-772 1631019 denotes 34
15320950-10686597-12070992 1116-1118 10686597 denotes 38
15320950-1631019-12070993 1386-1388 1631019 denotes 37
15320950-14977399-12070994 1705-1707 14977399 denotes 39