PMC:5157985 / 33159-33709 JSONTXT

{"project":"PubTator4TogoVar","denotations":[{"id":"9554","span":{"begin":11,"end":20},"obj":"SNP"},{"id":"9555","span":{"begin":370,"end":379},"obj":"SNP"}],"attributes":[{"id":"A9554","pred":"resolved_to","subj":"9554","obj":"tmVar:rs3783118;VariantGroup:0;CorrespondingGene:84945;RS#:3783118;CorrespondingSpecies:9606"},{"id":"A9555","pred":"resolved_to","subj":"9555","obj":"tmVar:rs3783118;VariantGroup:0;CorrespondingGene:84945;RS#:3783118;CorrespondingSpecies:9606"}],"text":"The ABHD13 rs3783118 A/C, located in the Ascaris susceptibility locus (Cr. 13q33.3), was under-represented in the group of high responders to Ascaris under the dominant model. Quantile regression confirmed this finding showing significant association with lower IgE levels (padj = 0.00001). In the CGA dataset we found that, as occurred with the Ascaris extract, ABHD13 rs3783118 was associated with lower levels of IgE to D. pteronyssinus under dominant model. This effect was driven by one or two copies of the minor allele C (padj = 0.03), Fig 3B."}

{"project":"PubTatorOnTogoVar","denotations":[{"id":"9554","span":{"begin":11,"end":20},"obj":"SNP"},{"id":"9555","span":{"begin":370,"end":379},"obj":"SNP"},{"id":"T1","span":{"begin":11,"end":20},"obj":"SNP"},{"id":"T2","span":{"begin":370,"end":379},"obj":"SNP"}],"attributes":[{"id":"A9554","pred":"resolved_to","subj":"9554","obj":"tmVar:rs3783118;VariantGroup:0;CorrespondingGene:84945;RS#:3783118;CorrespondingSpecies:9606"},{"id":"A9555","pred":"resolved_to","subj":"9555","obj":"tmVar:rs3783118;VariantGroup:0;CorrespondingGene:84945;RS#:3783118;CorrespondingSpecies:9606"}],"text":"The ABHD13 rs3783118 A/C, located in the Ascaris susceptibility locus (Cr. 13q33.3), was under-represented in the group of high responders to Ascaris under the dominant model. Quantile regression confirmed this finding showing significant association with lower IgE levels (padj = 0.00001). In the CGA dataset we found that, as occurred with the Ascaris extract, ABHD13 rs3783118 was associated with lower levels of IgE to D. pteronyssinus under dominant model. This effect was driven by one or two copies of the minor allele C (padj = 0.03), Fig 3B."}