PMC:5118444 / 34398-35165 JSONTXT

{"project":"2_test","denotations":[{"id":"27920798-27005566-33484712","span":{"begin":404,"end":408},"obj":"27005566"}],"text":"It should be noted that the tissues used in this analysis were downloaded from the NCBI database and did not originate from the same samples in which our CNV were detected. This is a major limitation in our tissue specificity analysis. As mentioned before, concordance between individual cattle CNV studies tends to be quite low. Cattle CNVs have also been shown to be lineage-differentiated (Xu et al., 2016). Therefore, it is quite possible that CNVs in the samples used for RNA sequencing could be quite different from those identified in this study. Hence, the tissue-specific expression patterns of CNV genes warrants further investigation using a dataset that includes whole-genome sequence as well RNA sequence from multiple tissues in the same set of samples."}

{"project":"MyTest","denotations":[{"id":"27920798-27005566-33484712","span":{"begin":404,"end":408},"obj":"27005566"}],"namespaces":[{"prefix":"_base","uri":"https://www.uniprot.org/uniprot/testbase"},{"prefix":"UniProtKB","uri":"https://www.uniprot.org/uniprot/"},{"prefix":"uniprot","uri":"https://www.uniprot.org/uniprotkb/"}],"text":"It should be noted that the tissues used in this analysis were downloaded from the NCBI database and did not originate from the same samples in which our CNV were detected. This is a major limitation in our tissue specificity analysis. As mentioned before, concordance between individual cattle CNV studies tends to be quite low. Cattle CNVs have also been shown to be lineage-differentiated (Xu et al., 2016). Therefore, it is quite possible that CNVs in the samples used for RNA sequencing could be quite different from those identified in this study. Hence, the tissue-specific expression patterns of CNV genes warrants further investigation using a dataset that includes whole-genome sequence as well RNA sequence from multiple tissues in the same set of samples."}