PMC:5118444 / 15282-16067 JSONTXT

{"project":"2_test","denotations":[{"id":"27920798-24303503-33484683","span":{"begin":280,"end":284},"obj":"24303503"}],"text":"Putative CNVs across the population of 175 bulls were identified using the exome cn.MOPS software package (Supplementary Table 1B). We chose to use the cn.MOPS package since it has been shown to have a lower false-positive rate than other exome CNV detection methods (Guo et al., 2013). CNVs were then merged across samples into CNVRs. In this work, we aimed to study common coding sequence CNVs across the Bos taurus genome. In an attempt to filter out possible false-positive and rare CNVs, CNVRs were filtered out if they were not present in at least 3 samples (\u003e2% of the population). Note that the 2% threshold was chosen arbitrarily. A total of 74 CNVRs were filtered out in this step. The final set of CNVRs consisted of 57 CNVRs (48 on the autosomes and 9 on the X chromosome)."}

{"project":"MyTest","denotations":[{"id":"27920798-24303503-33484683","span":{"begin":280,"end":284},"obj":"24303503"}],"namespaces":[{"prefix":"_base","uri":"https://www.uniprot.org/uniprot/testbase"},{"prefix":"UniProtKB","uri":"https://www.uniprot.org/uniprot/"},{"prefix":"uniprot","uri":"https://www.uniprot.org/uniprotkb/"}],"text":"Putative CNVs across the population of 175 bulls were identified using the exome cn.MOPS software package (Supplementary Table 1B). We chose to use the cn.MOPS package since it has been shown to have a lower false-positive rate than other exome CNV detection methods (Guo et al., 2013). CNVs were then merged across samples into CNVRs. In this work, we aimed to study common coding sequence CNVs across the Bos taurus genome. In an attempt to filter out possible false-positive and rare CNVs, CNVRs were filtered out if they were not present in at least 3 samples (\u003e2% of the population). Note that the 2% threshold was chosen arbitrarily. A total of 74 CNVRs were filtered out in this step. The final set of CNVRs consisted of 57 CNVRs (48 on the autosomes and 9 on the X chromosome)."}