PMC:5118444 / 1368-2288 JSONTXT

{"target":"http://pubannotation.org/docs/sourcedb/PMC/sourceid/5118444","sourcedb":"PMC","sourceid":"5118444","source_url":"https://www.ncbi.nlm.nih.gov/pmc/5118444","text":"Copy number variations (CNVs) are gains and losses of large regions of genomic sequence between individuals of a species (Mills et al., 2011). CNVs have been well-studied and linked to various phenotypic traits and diseases in humans and rodents (Cook and Scherer, 2008; Almal and Padh, 2012; Girirajan et al., 2013). Initial CNV studies have been performed in a number of domesticated animals: dog (Nicholas et al., 2011; Alvarez and Akey, 2012; Berglund et al., 2012), sheep (Fontanesi et al., 2011; Liu et al., 2013), pig (Fadista et al., 2008; Ramayo-Caldas et al., 2010; Chen et al., 2012; Paudel et al., 2013, 2015), chicken (Crooijmans et al., 2013; Yi et al., 2014), and goat (Fontanesi et al., 2010). These studies have linked many phenotypic traits to CNV, including chicken pea-comb phenotype (Wright et al., 2009) and white coat color in pigs and sheep (Johansson Moller et al., 1996; Norris and Whan, 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