PMC:5118429 / 38009-39008 JSONTXT

{"project":"2_test","denotations":[{"id":"27920797-21525308-33226493","span":{"begin":427,"end":431},"obj":"21525308"},{"id":"27920797-23967015-33226494","span":{"begin":695,"end":699},"obj":"23967015"},{"id":"27920797-21525308-33226495","span":{"begin":854,"end":858},"obj":"21525308"}],"text":"A number of genes detected by wssGWAS analysis within windows responsible for 1.0% or greater of the trait variance have been identified in mammalian systems as significant for muscle development, particularly with respect to the maintenance of hyperplastic capacity. Rainbow trout exhibit indeterminate growth potential as they have the ability increase both body length and muscle mass throughout adulthood (Johnston et al., 2011). A physiological mechanism unique to indeterminate growers is the ability to maintain a population of myogenic precursor cells with proliferative capacity that then differentiate into myotubes or contribute to nuclear accretion (Mommsen, 2001; Froehlich et al., 2013). Therefore, the continued ability for hyperplasia and hypertrophy in skeletal muscle contributes to the indeterminate growth phenotype (Johnston et al., 2011). In this regard, SNPs affecting genes related to myogenic and cell proliferation mechanisms are expected to affect growth and fillet yield."}

{"project":"MyTest","denotations":[{"id":"27920797-21525308-33226493","span":{"begin":427,"end":431},"obj":"21525308"},{"id":"27920797-23967015-33226494","span":{"begin":695,"end":699},"obj":"23967015"},{"id":"27920797-21525308-33226495","span":{"begin":854,"end":858},"obj":"21525308"}],"namespaces":[{"prefix":"_base","uri":"https://www.uniprot.org/uniprot/testbase"},{"prefix":"UniProtKB","uri":"https://www.uniprot.org/uniprot/"},{"prefix":"uniprot","uri":"https://www.uniprot.org/uniprotkb/"}],"text":"A number of genes detected by wssGWAS analysis within windows responsible for 1.0% or greater of the trait variance have been identified in mammalian systems as significant for muscle development, particularly with respect to the maintenance of hyperplastic capacity. Rainbow trout exhibit indeterminate growth potential as they have the ability increase both body length and muscle mass throughout adulthood (Johnston et al., 2011). A physiological mechanism unique to indeterminate growers is the ability to maintain a population of myogenic precursor cells with proliferative capacity that then differentiate into myotubes or contribute to nuclear accretion (Mommsen, 2001; Froehlich et al., 2013). Therefore, the continued ability for hyperplasia and hypertrophy in skeletal muscle contributes to the indeterminate growth phenotype (Johnston et al., 2011). In this regard, SNPs affecting genes related to myogenic and cell proliferation mechanisms are expected to affect growth and fillet yield."}