PMC:509282 / 7767-8329 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/509282","sourcedb":"PMC","sourceid":"509282","source_url":"https://www.ncbi.nlm.nih.gov/pmc/509282","text":"Insulin resistance with compensatory hyperinsulinemia is a prominent feature of metabolic syndrome. The most common reason for the development of hyperinsulinemia in insulin resistance is obesity. It stands as one of the major cardiovascular risk factors in patients with obesity. The present study on HFD rats demonstrated higher plasma insulin levels than control values. This marked hyperinsulinemia could be due to a combination of increased β-cell mass and decreased insulin clearance, as well as failure of insulin to suppress hepatic gluconeogenesis [14].","tracks":[{"project":"2_test","denotations":[{"id":"15287987-10949030-66505215","span":{"begin":558,"end":560},"obj":"10949030"}],"attributes":[{"subj":"15287987-10949030-66505215","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"2_test","color":"#b1ec93","default":true}]}]}}