PMC:509282 / 7132-7766 JSONTXT

{"project":"2_test","denotations":[{"id":"15287987-8621018-66505212","span":{"begin":281,"end":283},"obj":"8621018"},{"id":"15287987-13990765-66505213","span":{"begin":428,"end":430},"obj":"13990765"},{"id":"15287987-10408254-66505214","span":{"begin":630,"end":632},"obj":"10408254"}],"text":"Hyperglycemia is observed in insulin resistance where glucose utilization is reduced. We saw significant elevations in blood glucose levels. Intraperitoneal glucose tolerance tests confirm severe glucose intolerance. Oversupply of dietary lipids causes insulin resistance in rats [11]. Randle glucose fatty acid cycle suggested that the body prefers excess lipid stores to glucose for metabolic oxidation in insulin resistance [12]. Our HFD model also exhibited high plasma triglyceride levels. Hence studies on our experimental model in compliance with Randle et al findings suggested that HFD feeding causes insulin resistance [13]."}