PMC:5069600 / 13648-14427 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/5069600","sourcedb":"PMC","sourceid":"5069600","source_url":"https://www.ncbi.nlm.nih.gov/pmc/5069600","text":"Cognitive Assessment and Neuroimaging\nIn some patients, we performed brain magnetic resonance imaging (MRI) or computed tomography (CT), and a neuropsychological examination including the Mini–Mental State Examination (MMSE; 0–30 scale, normal \u003e24)24 and the Alzheimer's Disease Assessment Scale‐Cognitive Behavior Section (ADAS‐cog; 0–70 scale, normal \u003c10).25 We also evaluated patient 1 (P1) with amyloid positron emission tomography (PET) imaging with 11C‐PIB (Pittsburgh compound‐B). PET data were acquired on a Discovery PET/CT 710 (GE Healthcare, Tokyo, Japan) after the injection of 11C‐PiB (470 MBq). 11C‐PiB images were derived from dynamic summations of standard uptake values (SUVs) over 60 minutes and were normalized with the cerebellum as a reference region (SUVR).","divisions":[{"label":"Title","span":{"begin":0,"end":37}}],"tracks":[]}