PMC:4996403 / 9241-10087 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/4996403","sourcedb":"PMC","sourceid":"4996403","source_url":"https://www.ncbi.nlm.nih.gov/pmc/4996403","text":"3.6. Long-Noncoding RNA (LncRNA) Array\nMore recently, lncRNAs, generally defined as short RNAs greater than 200 nt in length, have risen to prominence with important roles in a broad range of biological processes [60]. LncRNAs regulate gene expression at the level of post-transcriptional processing such as protein synthesis, RNA maturation, transport, cell differentiation, immune responses, and activity and localization of protein coding genes [61,62]. They also exert their effects in transcriptional gene silencing through the regulation of chromatin structure [60,63]. Dysregulation of lncRNAs is associated with many human diseases, including various types of cancers [64]. Many studies have used lncRNA microarrays to demonstrate lncRNA gene expression profiles and the prognostic potential of lncRNA profiles in various cancers [65,66].","divisions":[{"label":"Title","span":{"begin":0,"end":38}}],"tracks":[{"project":"2_test","denotations":[{"id":"27600234-9634850-69479932","span":{"begin":214,"end":216},"obj":"9634850"},{"id":"27600234-9865919-69479933","span":{"begin":449,"end":451},"obj":"9865919"},{"id":"27600234-10348345-69479934","span":{"begin":452,"end":454},"obj":"10348345"},{"id":"27600234-9634850-69479935","span":{"begin":568,"end":570},"obj":"9634850"},{"id":"27600234-10729832-69479936","span":{"begin":571,"end":573},"obj":"10729832"},{"id":"27600234-9988266-69479937","span":{"begin":677,"end":679},"obj":"9988266"},{"id":"27600234-11309270-69479938","span":{"begin":839,"end":841},"obj":"11309270"},{"id":"27600234-11731411-69479939","span":{"begin":842,"end":844},"obj":"11731411"}],"attributes":[{"subj":"27600234-9634850-69479932","pred":"source","obj":"2_test"},{"subj":"27600234-9865919-69479933","pred":"source","obj":"2_test"},{"subj":"27600234-10348345-69479934","pred":"source","obj":"2_test"},{"subj":"27600234-9634850-69479935","pred":"source","obj":"2_test"},{"subj":"27600234-10729832-69479936","pred":"source","obj":"2_test"},{"subj":"27600234-9988266-69479937","pred":"source","obj":"2_test"},{"subj":"27600234-11309270-69479938","pred":"source","obj":"2_test"},{"subj":"27600234-11731411-69479939","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"2_test","color":"#ec93c1","default":true}]}]}}